I! Handle with EXTREME CARE This volume is BRITTLE Photocopy only if n.;::"?.'- PRINCIPLES FORENSIC MEDICINE, I -^^\j-J(^'J>£ ^/6'APJS/J:r2i^.-4 PRINCIPLES /a.€yfitfem' .^ of Forensic Medicine, in which the several subject^ 'should he arranged in the same order, and treated in thelisftnle way, as in his lectures. This object has been kept in view in preparing the second edition for the press. The no less important object of condensation has been attained by the abbreviation or omission of the greater number of the illustrative cases quoted in the first edition, and of some of the tables, on which much labour had been expended. The references have also been curtailed, and authors' names have been occasionally substituted for a more exact reference to their works. The space thus gained has allowed of the introduction into this edition of several new subjects, and of a considerable y\ PREFACE. number of illustrative woodcuts, by which, it is believed, the value of the work has been much enhanced. In introducing this new feature, the author has merely given greater development to a practice now becoming com- mon, of illustrating medico-legal papers, and especially those on Toxicology, by wood-cuts. A page of engravings illus- trative of chemical apparatus has always formed a part of Dr. Christison's work on Poisons ; wood engravings are very largely used in the works on Materia Medica of Pereira and Royle ; and Casper's * Handbuch der Gerichtlichen Medicin ' has an atlas of coloured prints. The wood engravings, with the exception of those which show th^ appearance of the subhmates of arsenic, have been done expressly for this work ; and the greater number of them are not to be met with in any shape elsewhere. They were drawn and engraved under the author's direction, chiefly from coloured drawings, preparations, and microscopic spe- cimens in his own possession. The anatomical and patho-' logical subjects, some of the crystals, some of the roots and most of the seeds, were drawn by Dr. Westmacott, the re- mainder by Mr. Hart, by whom all the engravings were executed. As a general rule the more important subjects, such as Infanticide and Unsoundness of Mind in the first part, and Poisoning by Arsenic, Opium, and Strychnia in the third jiart, are the most fully treated and most largely illustrated ; but the space devoted to each subject has been determined PREFACE. less by its importance than by the length of the descriptions and discussions necessary to render it intelligible. It may be well to add that, while the entire work has been revised, and most parts of it condensed, many portions of it have been wholly rewritten. It is in the third part of the work, or that which treats of Toxicology, that the largest additions and alterations have been made ; so that the 165 pages devoted to this subject in the first edition have been extended to 237 in the present one. It is in this part, too, that the wood engravings will be found most numerous. In treating this important group of subjects, an attempt has been made to render the tests for the poisons more easy of comprehension, and to impress them more eflfectually on the memory, by distinguishing between the properties of the several poisons and their tests, and by arranging the tests, as much as possible, in the order in which they would be ap- plied, on the supposition that the substance submitted to analysis was unknown, the most characteristic reactions being added. Some of the properties and tests of the alkaloids and other active principles of the animal and vegetable kingdoms are stated as results of an inquiry still in progress. The portion of the work relating to the properties and tests of arsenic and arsenious acid has been remodelled in con- sequence of the unexpected discovery of the globular form of metallic arsenic, as deposited from its vapour. In the case of some of the more important poisons, the value of individual Vlll PREFACE. symptoms, and the duration of the poisoning, have been de- duced from an extensive and careful analysis of cases. In the preface to the first edition the author had to ac- knowledge his obligations, in a special manner, to Beck's learned and elaborate Elements of Medical Jurisprudence; to Ray's Medical Jurisprudence of Insanity ; to Dr. Gavin's work on Feigned Diseases; to the Elements of Medical Jurisprudence of Dr. A. Taylor; to Watson's Medico- legal Treatise on Homicide ; and to the standard work on Poisons of Dr. Christison ; as well as to several foreign monographs and systematic works. To this list must be added, as works of constant and neces- sary reference, the learned treatises on Medical Jurisprudence and on Poisons, as well as the valuable toxicological Essays of Dr. Taylor, the Elements of Materia Medica of Dr. Pereira, and the Elements of Chemistry of Dr. Miller. The author has also much pleasure in recording his obligations to his friend Dr. John Harley, Medical Tutor of King's College, for his assistance in revising the press, as well as for his faithful drawings of some microscopic objects, and his useful and valuable suggestions. 26 Gordon Street, January, 18GI. CONTENTS. Page Introduction (including the subject of Medical evidence) . xv PART I. CHAPTER I. Personal Identity — Age — Sex ...... 1 CHAPTER II. Impotence — Rape — Pregnancy —Delivery, . . . .24 CHAPTER III. Foeticide — Infanticide — Legitimacy , . . . .63 CHAPTER IV. Life-assurance — Feigned Diseases 129 CHAPTER V. Unsoundness of Mind ........ 149 CONTENTS. PART II. CHAPTER I. Page Persons found dead — Real and Apparent Death — Sudden Death — Survivorship 202 CHAPTER II. Drowning — Hanging — Strangulation — Suffocation . . . 230 CHAPTER III. Wounds and Mechanical Injuries » 255 CHAPTER IV. Death by Fire — Spontaneous Combustion — Death by Lightning — By Cold— By Starvation 285 PART III. Toxicology. CHAPTER I. On Poisons in General 293 CHAPTER II. Irritant Poisons 316 CHAPTER HI. Mineral Acids — Sulphuric Acid — Nitric Acid — Hydrochloric Acid 325 CHAPTER IV. The Alkalis and their Carbonates — Potash — Soda — Ammonia — and their Carbonates 340 CHAPTER V. The. Vegetable Acids — Oxalic Acid, and Binoxalate of Potash — Tartaric Acid, and Bitartrate of Potash — Citric Acid . . 344 CONTENTS. XI CHAPTER VI. Page Salts of the Alkalis and Earths — The Nitrate and Sulphate of Potash — the Sulphate of Alumina and Potash — the Sulphuret of Potassium — the Chloride of Sodium — the Chlorides of Lime, Soda, and Potash — and the Salts of Baryta .... 351 CHAPTER VII. Vegetable Irritants — Purgative Medicines — Savin — Yew — Meze- reon — Arum — Colchicum — Veratrum album — Helleborus niger — and Diseased and Decayed Vegetable Matters . . 355 CHAPTER Vni. Animal Irritants — Cantharides — Poisonous Fish — and Diseased and Decayed Animal Matters . . . . . ,360 CHAPTER IX. Irritant Gases — Nitrous Acid Gas — Sulphurous Acid Gas — Hydro- chloric Acid Gas — Chlorine — and Ammonia . . .363 CHAPTER X. Specific Irritans — Phosphorus — Iodine — and Iodide of Potassium 364 CHAPTER XI. Arsenic and its Preparations — Antimony and its Preparations — Mercury and its Preparations — Lead and its Preparations — Copper and its Preparations — Zinc, Tin, Silver, Iron, Bismuth, Chrome, and their Preparations 367 CHAPTER Xn. Narcotic Poisons 435 CHAPTER XIII. Opium and its Preparations — Morphia and its Salts . . . 439 CHAPTER XIV. Hydrocyanic Acid — and the Cyanides — Oil of Bitter Almonds — Laurel Water . . . . . . . . . 450 CHAPTER XV. Poisoning by Alcohol, ^Ether, and Chloroform .... 469 Xll CONTENTS. CHAPTER XVI. Page Poisoning by Narcotic Gases — Carbonic Acid — Sulphuretted Hy- drogen— and Carburetted Hydrogen 475 CHAPTER XVn. Narcotico-acrid Poisons 485 CHAPTER XVni. Nux Vomica — Strychnia — Brucia 488 CHAPTER XIX. Belladonna — Hyoscyamus — Stramonium— Camphor — (Enanthe Crocata — Cocculus Indicus — Lolium temulentuni — Poisonous Mushrooms ......... 502 CHAPTER XX. Aconite — Digitalis — Tobacco — Lobelia Inflata — Conium . .512 CHAPTER XXI. Ergot of Rye — Cicuta Virosa — Phellandrium Aquaticum — /Ethusa Cynapium — Cytisus Laburnum — Solanum Nigrum . 526 CHAPTER XXII. Oil of Turpentine— on of Tar — Kreasote— Oil of Dippel . .529 LIST OF WOOD ENGRAVINGS. Fig. Page 1. The jaw-bone in old age 16 2. Male and female pelvis . . . . . . .21 3. Spermatozoa 41 4. Trichomonas vagince ....... 42 5. Developed air-cells ....... 79 6. Air-cells and air vesicles in foetal lungs . . . .80 7. Diagram of foetal circulation 98 8. Foramen ovale ........ 99 9. Human blood-corpuscles ....... 264 10. Crystals of hsemine ....... 266 11. Blood-corpuscles in man and animals .... 268 12 & 13. The gullet in poisoning by hydrochloric acid . . 338 14. The stomach in poisoning by hydrochloric acid . . . 338 15. Seeds of colchicum 357 15*. Globules of metallic arsenic ...... 369 16. Reduction tube 371 17. Reduction tube (new form) 372 18&19. The regular octahedron 372 20. Appearances of the opaque octahedron .... 373 21. Appearances of the transparent octahedron . . . 373 22. The lengthened octahedron 373 23. Trefoil-variety of the octahedron 374 24. The half octahedron 374 25. Appearances of the half octahedron 374 26. Twin crystals 374 27. Group of crystals of arsenious acid sublimed . . . 375 28. Reduction tube with arsenical crust 375 29 & 30. Mixed crusts of arsenic and arsenious acid by reflected light 377 31. Mixed crust of arsenic and arsenious acid (by transmitted light), showing globules of the metal .... 377 32. Crust of pure metallic arsenic, showing globules . , 377 33. Apparatus for transferring stains of arsenic from an opaque to a transparent surface . . . . . .378 34. Capillary reduction tube 378 35. Capillary tube mounted for the microscope , . , 379 36. Drop bottle . . : 380 Xiv LIST OF WOOD ENGRAVINGS. Fig. Page 37 it 38. Original forms of Marsh's apparatus . . . 382 39. Modern form of the same 382 40. Crust of arsenic in horizontal tubt» 384 41. Crust of antimony in horizontal tube .... 384 42. Form of apparatus for reducing arsenic by electrolysis . 387 43 & 44. The tetrahedron 401 • 45. Cube with the edges replaced by planes . . . .401 46. Microscopic forms of crystals of tartar emetic . . . 401 47 & 48. Crystals of corrosive sublimate (sublimed) . . 409 49. Globules of mercury 410 50. Globules of mercury and arsenic 411 49*. Lead tree 421 50*. Tin tree 433 51. Silver tree 433 52. Seeds of papaver somniferum 440 53. Form of crystals of morphia ...... 441 54. 55, & 56. Seed of the nux vomica 489 57. Microscopic appearance of the powder of nux vomica . . 490 58. Form of crystals of strychnia ...... 491 59 & 60. Microscopic crystals of strychnia . . . .491 61. Microscopic crystals of strychnia from its solution in chloro- form 494 62. Crystals of strychnia with acetic acid, carbazotic acid, and corrosive sublimate ....... 494 63. Seeds of belladonna 503 64. Seeds of hyoscyamus ....... 506 65. Seeds of stramonium ....... 508 66. Seeds of cocculus indicus 512 67 &; 68. Seeds of aconitum napellus 513 69 & 70. Roots of aconitum napellus 514 71. Root of the horse-radish ....... 514 72. Seeds of digitalis 518 73. Seeds of lobelia inflata 523 74 & 75. Seeds of conium maculatum .... 523-4 PRINCIPLES OF FORENSIC MEDICINE. INTRODUCTION. The state avails itself of the knowledge, experience, and skill of the medical man for three distinct purposes : — 1 . For the care and treat- ment of soldiers and sailors, prisoners, convicts, paupers, and lunatics, and other classes of persons for whose safety governments make them- selves responsible ; 2. As officers of health ; and 3. As skilled wit- nesses in courts of law. The duties which the medical man is called upon to perform in the first of these three capacities do not differ materially from those which devolve upon him in the ordinary practice of his profession, except that he is expected to give at least as much attention to the prevention as to the cui-e of disease, and to add to his medical and surgical skill a fair share of administrative talent. But as officers of health, and as witnesses iu courts of law, medical men are required to perform important and responsible duties for which the ordinary practice of their profession affords no adequate preparation, medical education, till of late years, no proper training, and medical literature no sufficient guidance. A consciousness of the distinctness, importance, and difficulty of the duties required of the medical man in these two capacities led at length to the establishment of a new and distinct science, taught in separate courses of lectures, treated of in separate works, and engaging the attention of many distinguished men more or less completely sepa- rated and set apart for the practice of the corresponding art. This new science and art was either made to embrace the whole of the duties which the medical man may be called upon to perform on behalf of the state, in which case it received the name of Political Medicine, or State-Medicine ; or it was divided into two sciences, the one under the title of Hygiene or Public Health, the other known indifferently as Forensic Medicine, Juridical Medicine, Legal Medicine, or Medical Jurisprudence. XVI INTRODUCTION. As the term Forensic Medicine expresses at least as clearly as any of the other terms the application of medical knowledge to legal purposes, it is employed in the title of this work. It is scarcely necessary to add that the term medico-legal is in common use, as in the phi-ases " medico-legal knowledge," " medico-legal experience," " medico-legal skill." The history of the science of Forensic Medicine resembles closely that of most other sciences. Necessity or convenience first gives birth to an art practised by individuals more or less skilful without any guidance from general principles ; the impoi-tance of the art, and the responsibility attached to the practice of it, soon create a demand for instruction, oral and wiitten, which instruction gradually assumes a systematic form ; and that which was so lately an art is universally recognized as a science. Thus the science of astronomy sprang from a rude art of navigation, and the science of medicine from an empirical art of healing. The science of Forensic Medicine, in like manner, took its rise in the necessity of bringing medical knowledge to bear on legal inquiries relating to personal injuries or loss of life ; the medical witness being at first without guide or instruction in the per- formance of his duty, and so continuing till a growing sense of the importance of his evidence, to society on the one hand, and to his own reputation on the other, created a demand for instruction which could not fail of being supplied. Cases were accordingly collected, arranged, and commented upon, illustrative facts were sought after, special experi- ments were devised and performed, till at length the medical witness received in books and lectures the same distinct instruction as the physician or surgeon at the bed-side had already derived from written or oral teaching in the theory and piactice of medicine, or of surgery. But the importance of medical testimony received an earlier recog- nition from some of the continental governments than from the public or the medical profession j for the appearance of the first medico-legal treatise (1597) was anticipated by nearly a century by the earliest state recognition (1507) of the necessity of medical evidence, and was followed within a few years by the appointment of medical men for the performance of medico-legal duties.* The history of Forensic Medicine as a science in England is of com- paratively recent date. It cannot be carried further back than the publication, in 1788, of Dr. Samuel Farr's Elements of Medical • The following dates have an historical interest. 'I'he penal code of tlie Bishop of Bamberg, proclaimed 1507. A uniform penal code adopted by tl>e Diet of Katisbon, 1532. The Covstitutio Crimmalis Carolina, publislied 1553. Presentation by Henry IV. of France of letters patent to his first physician, em- powering him to appoint two surgeons in every city and large town to ex- amine and report upon wounded or murdered persons, 1603. Publication at Frankfort of tlie Meihodus Testificandi of Condronchus, 1597, and of the works of Fortunatus Fidelis and Paul Zacchias in 1598 and 1621. First course of lectures on Forensic Medicine given by Micliaelis at Leipzig, about 1650. For a learned history of legal medicine, see Traill's Outlines of Medical Jurisprudence. IKTEODUCTION. XVll Juvisprudence ; and the science was first taught in lectures at the University of Edinburgh, in 1801, by Dr. Duncan, sen., the first pro- fessorship having been conferred by government on his sou in 1803. Since that date the science has made great and rapid progress; its importance is fully recognized by most of the examining bodies ; it is taught in all our medical schools ; its principles are being constantly applied in our courts of law ; and England is contributing her fair share of practiavl observation and original research towards its exten- sion and improvement. The application of the principles of the science to actual practice, or, in other words, the practice of Forensic Medicine as an art, devolves, for the most part, on the great body of medical practitioners. It is only in comparatively rare instances that those who have devoted special attention to the entire subject, or to important constituent paiis of it, such as Toxicology, or who have attained to eminence in special, branches of medical practice, such as midwifeiy and the treatment of the insane, are summoned to give evidence. in our courts of law. There are many reasons why the medical man should approach the performance of this class of duties with apprehension. He is conscious of the importance which attaches to his evidence ; he is wanting in that confidence which a more frequent appearance in the character of a witness would impart ; he is painfully alive to the unstable founda- tion upon which many medical opinions rest ; he knows that it is not easy in practice to observe the rules of evidence with which in theory he may have made himself acquainted ; and, above all, he shrinks from that publicity which attends all our legal proceedings, and from the unreasonable license allowed to counsel engaged not to discover truth but to achieve a victory for a client. Sympathizing in these reason- able apprehensions of the medical witness, some medical writers of eminence and most authors on Forensic Medicine have endeavoured to prepare him for the performance of his duties by setting forth the precautions he should observe both prior to and during his attendance in court. Information respecting the best mode of conducting pre- liminary medico-legal inquiries is generally to be found under the heads of " Post-mortem inspection," " General evidence of poisoning,' " Unsoundness of mind," or other subject to which the inquiry specially refers : the precautions to be observed, when he makes his appearance in the witness-box, are commonly treated of in a distinct Chapter under the title of Medical Evidence. This distinction is observed in these pages. Before proceeding to treat of the duties of the medical witness, it may be well to give some idea of the number of cases occurring year by year in England and Wales of a class to give rise to inedico-legal inquiries. Taking the year 1856 as the year concerning v/hich we have the most recent exact information, the Nineteenth Annual Repoit of the Kegistrar-General records the following figures : — XVin INTRODUCTION. Sudden deaths (causes unascertained) . . 3,474 Intemperance, privation, neglect, and cold . . ],123 Poison 432 External violence 13,352 Alalforinations, premature birth and debility, and atrophy 32,709 Totol . . . 51,095 The mixed class of deaths by external violence comprises 6,438 deaths by fractures and contusions, wounds, and other violence; 2,919 by burns and scalds; 2,681 by drowning (exclusive of deaths at sea) ; and 1,314 by hanging and sutibcation. The number of inquests to which these premature, sudden, and violent deatlis occurring in 1856 gave rise, was 21,801: and as the number of qualified practitioners in England and Wales falls far short of this number, it follows that, if the duty of attending at inquests were distributed equally, each member of the profession would attend at least one inquest every year. The committals for trial arising out of these 2 1 ,801 inquests amounted to 476, of which 205 were for murder, and 271 for manslaughter; and of this number 265 took their trial. In 1314 instances the death was returned as suicidal. The total number of cases requiring medical evidence in our higher courts of law may be judged of approximatively fi-om the printed returns of commitments for trial for offences against the person. In the year 1854 these commitments amounted to 1,849, and comprised 76 commitments for murder and attempts to murder attended with dangerous bodily injury ; various attempts to maim and injure, 159 ; assaults, and inflicting bodily harm, 276 ; manslaughter, 231; attempts to procure abortion, 5; concealment of birth, 61 ; rape, assaults with intent, &c., 268; unnatural offences, and assault with intent, 107. If we add 1 5 other cases of injury to the person not comprised in the printed returns under the head of " Offences against the Person," we have a total of nearly 1,200 cases on which it is highly probable that the evidence of medical men was required. If we add to these cases nearly 22,000 inquests, the civil cases in uhich skilled medical evidence is requiied, and proceedings in respect of lunatics, the occasions on which medical men are summoned to the service of the state will appear very consideiable — certainly numerous enough, and important enough in themselves to justify all the attempts which have been made to construct a science of Forensic Medicine, to teach it systematically in books and lectures, and to draw up a code of instructions for the guid- ance of the medical witness in the performance of his duties. INTROLUCTIOX. MEDICAL EVIDENCE. The duties which the medical man may be required to perform when summoned as a witness are twofold. He may have to state facts, and l>e may have to interpret them ; in other words, he may be, in the language of jurisprudence, both a common witness and a skilled witness. In some cases he is a common witness, in others a skilled witness ; and in others, again (and these are the majority of cases), he acts in both capacities. As a common witness, his duty is to state facts ; as a s^jtV^c? witness, to express his opinions. If he is examined as to facts which he has himself witnessed, he is also questioned as to his interpretation of them, and then he performs the double duty of a common and a skilled wit- ness ; but if summoned to state his opinion of the bearing and value of facts deposed to by others, he acts the part merely of a skilled witness. This distinction, between the duties of a common witness and of a skilled witness, has not always been recognized; and some medical men have fallen into the error of supposing that they were not required to express opinions, but merely to state facts. The law on this point is, however, quite plain. " The general rule is, that a witness must not be examined as to his opinion, for his testimony must be confined to evidence of facts. But in questions of skill and judgment, men of science or experience are allowed to give evidence of their opinion." " In criminal cases, the opinions of medical men of science are very frequently employed as evidence. A physician who has not seen the patient, may, after hearing the evidence of others, be called to prove, on his oath, the general eflect of the disease described by them, and its probable consequences in the particular case. So in prosecutions for murder medical men have constantly been allowed to state their opinion, whether the wounds described by witnesses were likely to be the cause of death."* In stating facts, and in drawing inferences from them, or from the evidence of other witnesses, there are certain precautions which the witness ought to observe, and certain legal requirements of which hb should not be ignorant. In the first place, he should approach the performance of his duties in a proper frame of mind. He should " use his best endeavours that his mind be clear and collected, unawed by fear, and uninfluenced by favour or enmity." (Percival.) The witness will find it difficult lo maintain this impartial frame of mind when the crime alleged is one of unusual enormity, when popular feeling runs high either for or against an accused person, or in times of public agitation, when a popular movement may seem to be endangered by evidence given in favour of an individual,' or when he is engaged distinctly for the prosecution or for the defence. In this latter case, he must not deem himself free * Burn's Justice, Title, Evidence. XX INTRODUCTION. from the risk of partiality, even though, after hearing all the facts upon which his opinion must be formed, and making i)roper personal inquiries, he feels that he can conscientiously give his evidence in favour of the party for whom he is retained. The medical witness requires to be specially cautioned against ex- pressing an opinion on the general merits of the case under inquiry, thus offending against an admitted principle of English law, that " when scientiHc men are called as witnesses, they are not entitled to give their opinion as to the merits of the ccise, but only as to the facts proved on the trial." Against this rule many eminent members of the medical profession have offended, and been reprimanded accordingly. A special caution is also required against a feeling of misplaced humanity, or an equally misplaced condemnation of the law on the score of undue severity. It was under the influence of both these feel- ings that the late Mr. Abernethy,* when speaking of the necessity for examining the lungs in all cases of suspected infanticide, gave express- si on to the unsound sentiment — " It is your duty, I think, to try to weaken the effect of your testimony on this point." This was a great error; for if there is one thing more essential for the medical witness to remember than another, it is, that he has nothing whatever to do with the consequences to which his opinions may lead, provided always that they are the result of cautious inquiry and due reflection. " The dread of innocent blood being brought upon us by explicit and honest testimony, is one of those superstitions which the nurse has taught, and which a liberal education ought to purge from the mind; and if, in the performance of our duty, innocence should unfortunately be involved in the punishment of guilt, we shall assuredly stand acquitted before God and our own consciences." (Percival.) The medical witness approaching his duties with a mind thus free from bias, requires some instruction as to the mode in which his evi- dence should be given. Bearing in mind the distinction already laid down between the duties of a common witness and of a skilled witness, he should be cautious not to obtrude his opinions when facts only are required of him, nor dogmatically to assert as facts things which are merely matters of opinion. He should answer the questions put to him, whether by the counsel, the court, or the jury, clearly and concisely, and if none of these elicit the whole truth, it is his duty to supply what is wanting. Such additions are always gratefully received by the court. The statements which the witness has to make, and the opinions he expresses, should be couched in the plainest and simplest language ; and he should avoid as much as possible all technical terms, and when it is absolutely necessary to use them, explain them in the clearest and simplest way. It is scarcely necessary to add, that he should care- fully avoid all figurative and metaphorical expressions. * Lectures, ' Lancet,' vol. xii. p. 227. INTRODUCTION. XXI The medical witness ought also to understand that he is not allowed to quote authorities in support of his opinions. The rejection of such appeals to authority has been unjustly stigmatized as " a compromise of the rights and dignity of the profession,"* and the rule of exclu- sion has not always been rigidly acted on. There can be no doubt, however, that the common usage of our courts of law is to disallow these appeals to authority. This exclusion of all appeals to authority is not attended with any bad effect, inasmuch as the medical witness is supposed to have made himself master of the opinions of the most eminent writers on the subject-matter of his evidence, and to have employed these opinions as the basis of his own inquiries and experience, so as to embody in his own evidence the opinions of the lending authorities of his profession. But though the medical witness is precluded from citing authorities, he may be made the medium of bringing them into play ; for he may be asked whether A or B is an esteemed authority with his profession, and whether he (the witness) coincides with some opinion expressed in his works. If the witness answers in the affirmative, he becomes the exponent of the opinion to which he has thus given his assent. The suggestions now made as to the mode in which the medical man ought to give his evidence will be of little use to him, unless he have previously prepared himself with care for the duty which he is about to discharge. It will contribute greatly to the right performance of this duty if he avail himself of the assistance and advice of other members of the profession, more especially of such as have devoted some attention to medico-legal inquiries. It has been recommended, too, that the medical witnesses about to be examined should first meet together and agree on the opinions which they shall express. The foregoing observations relate chiefly to the mode in which the medical witness should give his evidence ; the precautions to be taken in order that his evidence may be admissible still remain to be con- sidered. These precautions may be treated under the heads of Notes, Confessions, and Death-bed declarations. Notes. — When observing any facts which, at a future time, may become the subject-matter for legal inquiry, the medical man should not trust to his memory, but commit the facts to writing. This should be done, either on the spot, or as soon as possible after the transaction to which they relate. If, as in performing a post-mortem examination, it is necessary to resort to dictation, the notes of the amanuensis should be immediately examined and corrected. These notes may afterwards be used by the witness in court to refresh h.\?, memory, but not to supply its place. If the facts were not committed to writing till some time after the events to which they refer, or if, having been made at the proper time, they have been entirely forgotten, the notes will be of no use to him. Confessions. — The medical man may receive confessions of guilt * Smith, 'Analysis of Medical Evidence,' p. 128. XXll INTRODUCTION. from those whom he is called upon to attend professionally, and it is important that he should know under what conditions these are admis- sible in a court of law. " A confession, in order to be admissible, must be free and volun- tary, that is, must not be extracted by any sort of threats or violence, nor obtained by any direct or implied promises, however slight, nor by the exertion of any improper influence." The duty of the medical man with regard to confessions is, therefore, clear. If called upon to receive a confession, he must take care not to hold out any sort of inducement to make it ; he must avoid suggesting matter for the confession by lead- ing questions ; he must receive what is said to him without comment, reduce it to writing as soon as possible, read it over to the person con- fessing, obtain his signature to it, and countersign it himself. The "medical man should also be careful to ascertain the state of bodily health and of the mind of the party making the confession. The necessity of this caution is well illustrated by cases quoted by Dr. Southwood Smith,* in which the mind was affected either by disease, or the chronic influence of hardships and exposure. To these examples might be added other confessions of murders never committed, and self-accusations of impossible crimes, such as witch- craft. Dying Declarations. — Dying declarations are admitted as evidence in cases of homicide, where the death of the deceased is the subject of the charge, and the circumstances of the death the subject of the declaration. They form an exception to the rule that all evidence in criminal cases must be given on oath ; and they are admitted on the principle that the party being at the point of death, and without hope of recovery, is induced to speak the truth by considerations as powerful as an oath administered in a court of justice. It follows, therefore, that a decla- ration, though proved to have been made by a person in a dying state, is not admissible unless it also appear that the deceased apprehended him- self to be in such a state as would oblige him soon to answer before his Maker for the truth or falsehood of his assertions. It is not necessary, however, that the deceased should express his apprehensions. His con- sciousness of approaching death may be inferred from the nature of the wound, or illness, or from other circumstances of the case. But if any hope whatever be entertained, whether spontaneously or on the sugges- tion of others, or even if it be inferred to exist, death-bed declarations cannot be leceived in evidence. " As the declarations of a dying man are admitted, on a supposition that in his awful situation, on the confines of a future world, he had no motives to misrepresent, but, on the contrary, the strongest motives to speak without disguise and without malice, it necessarily follows, that the party against whom they are produced as evidence may enter into the particulars of his state of mind and of his behaviour in his last moments, or may be allowed to show that the deceased was not • Lectures on Forensic Medicine, ' Med. Gazette,' vol. xxi. p. 628. INTRODUCTION. XXlll of such a character as was likely to be impressed by a religious sense of his approaching dissolution." Having thus stated the law respecting dying declaratic us, it will not be difficult to prescribe the course which the medical man ought to adopt when called upon to receive such declarations. As dying declara- tions are but confessions, made under a more solemn and binding sanc- tion, all that has been said on the subject of confessions is applicable here. The medical man should merely receive the declaration, with- out putting any leading questions, but confining himself to such inqui- ries as may be necessary to clear up any ambiguity in the dying man's statements. He should record the very words used, and, if there be time for it, he should commit the declaration to writing, read it to the dying man, and obtain his signature to it. If the declarant's death take place so suddenly that there is no time for this, he should make a memorandum of the conversation at once, while it is Iresh in his me- mory, and before the words used have escaped him. To this docu- ment the witness will be allowed to refer to refresh his memory when he gives his evidence. Another essential part of the medical man's duty is to ascertain the exact state of the declarant's mind, whether he is calm and collected, or otherwise, and whether he is under the infiuence of any particular bias, or undue feeling of resentment. It is scarcely necessary to remark that the medical witness may be examined as to conversations which may have taken place in the pre- sence of an accused party, with a view to ascertain his bearing and demeanour. When in attendance therefore on cases likely to become the subject of inquiry in a court of law, the medical man should be attentive to the words of speakers and the demeanour of listeners. It ought, however, to be understood that hearsay is not admissible as evidence unless it form pait of the res gesta. A medical witness, therefore, would not be allowed to cite a case of his own observing in support of his opinions if the case consisted in part, as it must needs do, of statements made by the patient, his friends, or attendants. It still remains to state the usage of our courts of law with regard to secrets confided to the medical man in the course of his professional attendance. " It was solemnly decided, in the case of the Duchess of Kingston, that in a court of justice medical men are bound to divulge these secrets when required to do so." " If a medical man," said Lord Mansfield on that occasion, *' was voluntarily to reveal these secrets, to be sure he would be guilty of a breach of honour and of great indiscretion ; but to give that information which by the law of the land he is bound to do, will never be imputed to him as any indis- cretion whatever." It may be necessary to wam the medical man against taking part in duels, even though his object in being present at them is to save iile, and not to destroy it. He should also understand that a witness is not obliged to give evidence which may tend to criminate himself. The following is a summary of the principal contents of this chapter. 1. As regards the state of the witness's mind. He should never XXIV INTRODUCTION. consider the general merits of the case, nor allow his mind to he swayed hy prejudice of any sort. He should guard most carefully against any biiis in favour of or against an accused party. 2. As to the mode of giving his evidence. He should not be forward to state facts or express opinions which are not actually called for; but, at the same time, he should withhold no statement which is essential to the information of the jury. He should use the plainest and the simplest language, avoiding, as much as possible, technical terms, and all metaphorical expressions. He should quote no authorities, bat merely state his own judgment. In cases of difficulty, he should, if practicable, provide the assistance of other medical men. 3. Circumstances affecting the admissibility of his evidence. In matters of importance, he should never trust to memory, but take notes ; at the time if possible, but if not, as soon as may be after the " facts or occurrences to which they refer. If he employs an amanu- ensis, he should examine and correct the notes at once. These notes may be used to refresh the memory, but not to supply its place. When called upon to receive a confession, he must take care to hold out no promise or threat of any sort. He must receive it without comm£7it, reduce it to wi'iting on the spot, read it over to the person making it, obtain his signature to it, and countersign it himself. In doing so, he must not omit to ascertain, to the best of his ability, the state of mind of the party making the confession. Similar rules apply to death-bed declarations. Such inquiries only should be made as are necessary to clear up any ambiguity in the dying man's statements. The very words used should be taken down ; and if there is time for it, they should be read to him, and his signature obtained. If the death take place so suddenly, that there is no time for this, a memorandum of the conversation should be made while the very words used by the dying man are fresh in the memory. In this case, as in that of con- fessions, every endeavour should be used to ascertain the state of the declarant's mind. The witness should also be attentive to the conver- sations held in cases likely to become the subject of judicial inquiry, and to the demeanour of the persons present at them or taking part in them. But he should bear in mind that Hearsay is only admissible as evidence when it forms part of the res gesta. 4. The medical man should further understand that he may be re- quired in a court of law to divulge the secrets confided to him by patients; that he may expose himself to a criminal prosecution for taking any part in duels ; and that he is not obliged to give evidence which would have the effect of criminating himself. Consult on the subject of this Chapter, Philips and Starkie on Evidence ; An Analysis of Medical Evidence, by John Gordon Smith, M.D. ; Amos's Lectures in the 7th Volume of the Medical Gazette ; Percival's Medical Ethics ; Archbold's Summary of the Law relative to Pleading and Evidence in Criminal Cases. Also Burn's Justice, by E. V. Williams, title Evidence. FOEENSIC MEDICINE. PART I. CHAPTER I. PERSONAL IDENTITY. AGE. SEX. TfiESE three subjects are thrown into one group, because they have u close connection with each other. Thus, the body or remains of some unknown person may be found, and it may be necessary to ascertain first the sex, then the age, and afterwards to identify the individual by means of peculiar and characteristic marks. In other instances these questions are raised separately. The three subjects are arranged in this Chapter in the order which appeared most convenient, the subject of sex occupying the last place, from its connection with the topics con- tained in tlie next Chapter. PERS6nAL IDENTITY. Questions of Identity are of frequent occurrence in our courts of law. A child claims an inheritance : is he the person he pretends to be? A man who has been robbed is required to identify the thief; and a witness may be examined as to the identity of a party with whom he is acquainted. There is one instance, also, in which a jury may be impannelled for the sole purpose of trying the question of identity, viz., where a prisoner after conviction makes his escape and is retaken. The question of identity may also be raised as to persons found dead ; and in coroners' inquests the very first step taken is to identify the body or any remains of it that may be found. The subject of personal identity, then, divides itself into 1, The Tdentity of the Living, and 2, The Identity of the Dead. B PERSONAL IDENTITY. 1. IDENTITY OF THE LIVING. In identifying living pereons the aid of a medical man is rarely required, unless in the case of deformities or injuries, the nature or effects of which he may be called upon to explain ; or where changes have l)een produced in the external appearance by the application of colouring ingredients to the skin or hair. But in order to give com- pleteness to the present subject, some questions will be briefly noticed which do not require medical evidence for their solution. In the case of parties claiming inheritance, much stress has been laid on family resemblance as a means of identification. Thus, in the celebrated Douglas case. Lord Mansfield said, " I have always considered likeness as an argument of a child's being the son of a parent. A man may survey ten thousand people before he sees two faces perfectly alike, and in an army of one hundred thousand men every one may be known from another. If there should be a likeness of feature, there may be a discriminancy of voice, a difference in the gestures, the smile, and various other things ; whereas, a family likeness runs generally through all these, for in everything there is a resemblance, as of features, size, attitude, and action." This case was decided in favour of the claimant, Archibald Douglas, in consequence of his proAX'd resemblance to Colonel Stewart, his father. The twin brother, Sholto, who died young, was proved to have equally resembled Mrs. Stewart, the mother. On the other hand, it ought not to be forgotten that persons having no connection by relationship or descent may bear the closest resemblance to each other, as in the following remarkable example. In the year 1772, one Mall, a barber's apprentice, was tried at the Old Bailey for robbing a Mrs. Ryan of Portland Street. The witnesses swore positively to the identity of the lad, and the whole court imagined him guilty. But he succeeded in proving his innocence by reference to the books of the court ; from which it appeared that on the day and hour when the robbery was committed the lad was on his trial at the bar where he then stood for another robbery, in which he was likewise unfortunate enough to be mistaken for the person who committed it. lu this same class of cases the question of identity may resolve itself into a consideration of the change which the lapse of time, coupled with fatigue, hardship, and privations, may produce in the personal appearance of the claimant. This question was raised in the case of Cassali, a noble Bolognese, who left his country at an early age, and was supposed to have lost his life in battle; but, after an absence of thirty years, returned and claimed his property, which his heirs had appropriated. The change in his appearance was so great that he was treiited as an impostor, and thrown into prison. The judges, being in doubt, consulted Zacchias, who in his consultation mentioned several causes which might produce such a change, as age, change of climate, diet, mode of life, and disease. IDENTITY OF THE LIVING. -3 Cassali had left home in the bloom of youth, had been exposed to the hardships of a military life, and if the claimant's account of himself might be believed, he had languished for years in prison. As the heirs could not prove the death of Cassali, the judges, influenced by the opinion of Zacchias, decreed that his estates should be restored to him. The question of identity assumes a more complicated form when some person more or less closely resembling the true claimant is brought forward, or presents himself, to contest the claimant's right. The reader will lind illustrations of both these frauds in the cases of Baronet and Martin Guerre, which, with that of Cassali already cited, and other leading cases from the ' Causes Celebres,' are quoted and criticised by Fodere in the second chapter of his ' Traite de Medecine Legale.' They will also be found in an English dress in Beck's ' jMedical Jurisprudence,' in the Chapter on Age and Identity. In many cases of disputed identity the difficulty has been solved by means of peculiar personal marks, upon which the medical man has been required to state his opinion. These marks are either nsevi materni, or moles, or defoi-mities, or the scars of foregone disease or injury. Even these personal marks, however, have been found, by a strange coinci- dence, to be present in two individuals otherwise closely resembling each other. Thus, Joseph Parker, who was tried at New York in 1804, on a charge of bigamy, not only closely resembled one Thomas Hoag, for whom he was mistaken, in general appeai-ance, but had in common with him a scar on the forehead, a small mark on the neck, and a lisp in his speech ; but, unlike Hoag, he had no scar on his foot. That he was Joseph Parker, and not Thomas Hoag, was also proved to the satisfaction of the jury by an alibi. (Beck, Chapter on Age and Identity.) In a Belgian case reported in one of the French Journals for 1847, a question of identity turned in some degree on the possibility of the removal of scars. The medical man, M. Vandelaei-, stated that scars might be removed by time or by artificial means, and the physicians of the pi-isons of Valvorde and Ghent confirmed this opinion by stating that prisoners are in the habit of effacing scars by applying a salted herring to them. MM. Lebeau and Limanges, on the other hand, contended that scars could not be removed. This latter opinion is doubtless the correct one ; though it must be admitted that scars grow less distinct with the lapse of time, and may also be rendered less dis- tinct by friction or the use of stimulants. The belief that they may entirely disappear is probably founded on the very slight marks often left by very extensive wounds when they heal by what is technically called the "first intention." Thus, in the case of a maniac who had completely removed the parts of generation, the situation of the wound was marked by so faint a white line that it might be overlooked by a casual observer ; and a severe flogging which has left the back quite raw at the time is traceable after an interval of some years only by 4 PERSONAL IDENTITY. very fine white lines upon the back and sides, and, where the knots had fiiUen, by little round pits resembling small white circles neatly cut out by a punch. In one case in which the author was consulted, the entire absence of both kinds of mark enabled him to state with confidence that the man coulil not have been, as it was alleged he had been, very severely flogged. The same remarks that apply to ordinary scars may be extended to the blue and red discolorations of the skin produced by the process of tattooing. They admit of removal only by the de- struction of the portion of skin in which they are seated, From what hcvs been just stated it will be infei-red that the exact shape and position of a s >0 i> >«:. «o •<* CO VO 7-H 02^ ss? i§ W (M I> (N CO l> CO ■s c ^ oi N .O C-1 IC i> ic vn VO vO vO •^ T-H rH f" o fS s§ Jr^ (M Tfi t> rH rji t- rH t}< II N .O (M !M t^ lO \o ^ ^ H a o ^t> C -1 Tt^ t> rH Ti^ 5i 2i " o g lO CO rH Ti^ c^ cc VO CM t> 1 sg ^ t* (N rf* O (M -^ t> C ^ 'o 1-1 CO lO ^ Oi VO C CO rH CO ^s 2^ ■^ o gCN O O >* O CO rjl VO 00 2 w5 £SS ^-'+1 !M CO lO 1-1 CO VO rH CO ^ ,c 2| NO T}< (M CO ■<*< (N CO '^ < a 0} S « « .2 i_l£ S £ 6 j_a_s S OS ^ .2 1 ^"1 LENGTH OF THE FOETUS AT DIFFERENT AGES. 67 B 9 wM Sf^ got>OS OOt- OOt- g CO T-i o o CO xo Si-ioo -^ o Oi ^t>-H W5 .5 35 as CO 00 CO c orft^ OO"^ I C OS C5 O O CO t> . O i - CO . Oi 05 tH ca5-^t>. t>»»OCO 05-^ oot- cot>T-i ooao a3coi> cococo ocoo .C CO '-' tH t> CO t:^ CO CCOCOiC COCOOl CO CO '-I g r> (M lO CD (M ■rt' C CO 1-1 tJ< CO CO ^ CO tH TiH CO - C O CO O r-' O -i< q t}< O ^ CO (M -^ .gooco cooco coo-H COCO^ l-lOlO 1-HC01> T-H tH -+OC^1 COCMTf CPOCO X rj c; ^ C CS s s s s s a f<^^.§ iS as -5 ■J- ■^ ^ll^ >'.f H'^^'S 03 t*- n ^•^::2 s^ •r:(N ® o "Opfl supe and tance tlyal] So 52 TO were made under the ributed by Dr. Geogehan) ete the number. One ins m the table, as being grea ^"1 ll •s^ 1! TS "3 Sl§-£ §S chm , CO tted •9^ c .S3 M^^ a oi ons, frcd , Ma thes or- P-^S^ S^.- S3 ;?■ O a ay r>.^z ds -4J O g-rfSo., .as g^ ^ o to.c o o t- M S 0) o 2 >-l « acn '. "O 2 S c2 -ES ^ £ ^ 68 F(ETICIDE. The weight of the foetus at full term has been made the subject of many investigations, and as this point is of importance in itself, and interesting as throwing light upon the probable limits of variation at earlier periods of utero-gestation, the results, as deduced from upwards of 20,000 observations, by Quetelet, Camus, Le'cieux, and Baudelocque, and by Drs. Macaulay and Clark, including the facts in the preceding table, are subjoined : — Gi'eatest weight .... 14 lbs. Least weight .... 2 lbs. 6 oz. Average weight .... 6 lbs. 11 oz. Instances are on record of weights greatly exceeding even the maximum now stated. Dr. Merriman records one exceeding 14 lbs. Sir Richard Croft one, and Dewees two, of 15 lbs., Dr. Kamsbotham senior, and Dr. Moore, of New York, instances of 16^ lbs,, and Mr. Owens, of Ludlow, one of 17 lbs. 12 oz. Even this great weight is said to have been exceeded. It is only necessary to add that, as a general rule, still-bom children are heavier than those born alive, males than females, single children, ceteris paribus, than twins, and twins than triplets. The length of the fa?tus at full term, as given by different English and French authors, is shown in the subjoined statement : — Greatest length . . . . 2fi inches. Least length . . . . 17 „ Average length . . . . 19 „ Cases are recorded in which the length has exceeded even this maxi- mum. Dewees, for instance, met with a length of 27 inches. The length, like the weight, is greater in males than in females, in still-born than in those born alive, and in single children than in twins, triplets, &c. The signs of maturity or immaturity will be gleaned from the history of the development of the foetus ; and they will be stated more at length under the head of legitimacy, on which question they have an important bearing. FCETICIDE, OR CRIMINAL ABORTION. The crime of abortion consists (see 1 Vic. cap. 85) in unlawfully administering to any woman, or causing to be taken by her, with intent to procure her miscarriage, any poison or other noxious thing, or in unlawfully using for the same purpose any instrument or other means whatsoever. If the words of the statute were taken literally it would not be necessary to prove that the woman to whom the poison or noxious thing had been given, or force in any way applied, with a view to pro- CAUSES OP ABOETION. 69 cure abortion, was really pregnant, or that abortion had followed the use of these means. The judges, however, have generally held the proof of pregnancy to be necessary. It will also be observed that the statute is silent as to the distinction between women quick and not quick with child. In trials for abortion, the first duty of the medical man will be to establish the fact of abortion by an examination of any substances which may have been discharged from the womb. Having ascer- tained that the substances submitted to his inspection are the products of conception, he may be required to determine wliether the abortion was due to natural causes, to the use of drugs, or to violence. For this purpose he will have to form an opinion as to the sufficiency of any means which may have been used to procure the miscarriage. In rare instances, also, he may have to examine the female to whom the corpus delicti is stated to belong, in order to determine whether or not she has been recently delivered. Three different examinations there- fore may be required. 1. An examination of substances expelled from the womb. 2. An inquiry intq the cause of the abortion : and 3. An examination of the female supposed to have miscarried. 1. Examination of Substances expelled from the Womb. — It is only in the early periods of gestation that this examination will offer any difficulty. When the embryo has attained a certain degree of develop- ment, it will be impossible to confound it with any other substance expelled from the uterus. The rule already laid down (p. 50), in speaking of moles and false membranes as signs of pregnancy, must be observed in cases of alleged abortion, viz. to admit no substance to be a product of conception in which distinct traces of an ovum cannot be recognized. To this rule hydatids form a solitary exception. Having ascertained that the substance submitted to our inspection is really a product of conception, we must next determine its age ; and this will be done by comparing it with the description already given of the growth and development of the embryo and foetus, p. 63, et seq. 2. Cause of the Abortion. — In considering the cause of an abortion attributed to the administration of drugs or the use of force, it is neces- sary to be armed with some preliminary knowledge respecting the occurrence of abortion from natural causes. This is known to be a very common event, especially in the early months of pregnancy, and it has been variously stated as occurring in 1 out of 12, or even (Dr. Granville) 1 in 3 of the total number of conceptions. Accoucheurs who have had to deal chiefly with women in more advanced periods of pregnancy have estimated the proportion much lower {e. g., 1 in 188, Madame La Chapelle). The causes which occasion this high proportion of mis- carriages will be conveniently coasidered under the title of Natural Causes of Abortion. — These are either (a) predisposing, or (6) exciting, a. The predisposing causes may affect either the female 70 F(ETICIDE. hereelf or the ovum. The females most liable to abortion are the plethoric, the irritable, the nervous, the lymphatic, the feeble, and the ailing. Excessive or irregular menstruation and leucorrhoea are also among the predisposing causes. Females attacked by syphilis, scurvy, asthma, and dropsy, and those affected with malignant diseases, are peculiarly liable to miscarry. Malformations of the pelvis, the small size of the pelvis in those who marry very early, tight lacing, and all diseases of the uterus or its appendages which tend to prevent the complete development of the organ, may be mentioned among the pre- disposing causes of abortion. To these may be added, a rigidity of the womb, as in those who are pregnant for the first time at a compara- tively advanced age, and a relaxed condition of the neck of that organ. Occasionally, abortion has been epidemic, depending upon some pecu- liar condition of atmosphere.* The predisposing causes of abortion dependent upon the condition of the ovum are very numerous, especially in the early months. Velpeau states that of upwards of 200 embryos expelled before the end of the third month, at least one half were diseased. The disease may exist in any part of the ovum — in the membranes, in the placenta, or in the foetus itself. The different forms of disease which may attack these several parts are too numerous to specify in this place ; suiKce it to observe, that where we can discover any marked disease of the foetus, or its annexes, we are justified in regarding such disease as affording a strong probability in favour of the abortion having been due to natural causes. A woman who has once miscarried is likely to miscarry again from the same cause, and at or about the same period of gestation ; and it is also usual to attribute a certain effect to the mere force of habit. In the woman, for instance, whom Heberden (' Commentaries,' p. 15), mentions as having miscarried 35 times, it is reasonable to attribute the later abortions in part to the force of habit. h. The occasional, or exciting causes of abortion, are not less numer- ous than the predisposing. Among them may be mentioned all strong and sudden actions of the muscles of the abdomen, in the stronger efforts of expiration, as in coughing, straining efforts to void the urine or faeces, &c. ; violent exercise, as in dancing ; profuse discharges from the bowels or from the womb itself; undue excitement of the genital organs ; blows, and various forms of mechanical injury. All these occasional or exciting causes will fail of producing abortion when the ovum is sound, and the female healthy ; while, on the other hand, the most careful abstinence from all the exciting causes will not prevent abortion when the predisposition from either cause is strong. The criminal means resorted to with a view of destroying the foetus are best divided into two classes, general and local ; the first acting * See references to these epidemics in Velpeau's ' Art des Accouchemens,' art. Avortement. CONSTITUTIONAL MEANS. VENiESECTION, ETC. 71 through the constitution of the mother; the second by immediate application to the abdomen or uterus. 1. Constitutional Means. VencBsection. — The confidence placed by the vulgar in this remedy comes, like many other popular fallacies, from high medical authority — that of Hippocrates. But it is merely a vulgar error. It is a notorious fact that pregnant women bear blood- letting well, and that it is often the best means of averting a threatened abortion. The assumption that blood-letting promotes abortion is moreover rebutted by facts adduced by several high authorities. Cases are recorded of women bled 48, 80, and 87 times in the course of their pregnancies, and yet without occasioning miscarriage ; and Dr. Rush, who bled very freely in the yellow fever of 1793, asserts that not one pregnant woman to whom he prescribed bleeding died or miscarried. The popular belief in the efficacy of the abstraction of blood from the foot seems to rest on no better foundation, nor does the removal of blood by leeches applied to the anus or vulva — a practice much less frequently resorted to in this country than in France — appear to pos- sess any peculiar efficacy. Emetics. — It is well known that during the early months of preg- nancy, and even in some instances throughout the entire duration of it, severe and distressing vomiting occurs, but without producing abor- tion. This fact affords some presumption against the efficacy of emetics — a presumption strengthened by the failure of several active irritant poisons productive of violent vomiting in bringing about miscarriage. In females strongly predisposed to abortion emetics would, however, be likely to occasion it. Cathartics. — These remedies, too, may be given repeatedly, and in very large doses, without producing abortion. Dr. Rush's experience in the yellow fever of 1793 is conclusive on this point.* But it is not to be doubted that hypercatharsis, but especially that resulting from remedies acting chiefly on the rectum, is not without danger to the life of the foetus, when there is a decided predisposition to abortion. Diuretics. — These remedies are mentioned as calculated to produce abortion, but without sufficient reason. Irritant poisons, which act in moderate doses as diuretics (e. g., nitre), may occasion abortion ; but not simply by their diuretic action. One of the iri'itant poisons which powerfully affects the urinary organs is specially deserving of notice in this place : namely, cantharides. This active substance combines the effect of a violent emetic, a strong purgative, and a most effective diuretic, and acts violently on the organs in the immediate neighbourhood of the uterus, viz., the bladder and the rectum, occasioning also intense fever and great debility ; and yet even this drug given in full doses may fail (as in a case related by Mr. Lucas, of Leeds) in producing abortion. The occasional and even frequent failure of such active poisons renders the efficacy of less * 'Med. Observations and Inquiries,' vol. iii. p. 249. 72 FffiTICIDE. powerful remedies extremely doubtful, unless there is in the female a very decided predisposition to miscarry. Emmenagogues. — Under this name avast number of active and inert remedies are classed, by far the majority of which have as little effect on the uterine system as they have on other parts of the body. The medicines which Beck notices under this head are savin, mercury, snakeroot, and pennyroyal. Snakeroot and pennyroyal do not appear to be very efficacious ; nor does mercury in the solid form, or in its preparations, even wheh given in very full doses, and to the extent of causing profuse salivation, appear to be attended with any risk of abortion ; but the Juniperus sabina has some pretensions to be considered a dangerous drug : for, in common with other irritant poisons, it has undoubtedly occasioned abortion in more than one instance, though it has failed in others, and in others, again, has sacrificed the life both of mother and child. Closely allied to the so-called emmenagogues is the secale cornutum, or ergot of rye, a medicine which possesses the remarkable property of exciting the muscular fibi-es of the uterus to contraction, and is in much too frequent use for that purpose. Concerning the efficacy of this remedy, much difference of opinion exists. Some authors have supposed that the power of the ergot is limited to the period of delivery, and to the state of full expansion and deve- lopment of the uterus. This opinion seems highly improbable, and cases are certainly recorded in which this active agent produced abor- tion at an earlier period of gestation ; and experiments on animals have shown that it is capable of producing abortion at any period. On the other hand, several cases are recorded both by l5r. Condie and by Dr. Beck, in which considerable doses of the ergot, often repeated, failed in producing abortion. The root of a plant called the Actea ramosa has the reputation of being nearly as active as the ergot. Digitalis has been named among the substances capable of producing abortion, on the authority of a case related by Dr. Campbell. The digitalis was given for dropsy; the child was still-born, and the mother died soon after, Mr. W. H. Dickinson (' Med, Chir. Trans.,' vol. xxxiv. p. 1) has shown that digitalis in such doses as from ^fs. to ^ifs. of the infusion, and TT\^xx. to TTT^xl. of the tincture, has a spe- cific action on the uterus ; and its power of producing abortion, though not proved, is to be inferred from the facts stated. It results from all these observations on the power of medicines to produce abortion : — That there is no one medicine which can be depended on as a means of procuring abortion in women not strongly pi-edisposed to miscarry ; that, if given in doses short of those which would risk the life of the mother, they would almost certainly fail of accomplishing their pui-pose ; that, where they do succeed, they place the life of the mother in jeopardy, and often sacrifice it ; and MECHANICAL MEANS. 73 that, for every case in which the mother escapes, there is prohably one at least in which the mother and her offspring both fall a sacrifice, and one in which the mother dies, the child remaining uninjured in the womb. The fact is, that none but poisons, or medicines administered in poisonous doses, can be expected to produce abortion in any case unless the predisposition to abortion is already very strong ; when such predisposition does not exist, the mother is much more likely to fall a sacrifice, whilst the child remains intact in the womb, or is even born alive, than the child to be expelled and the mother to survive ; in other cases both the mother and offspring will perish. Mechanical means. — These consist either of external violence applied to the abdomen or loins, or of instruments introduced into the riterus. External violence applied to the abdomen or loins is a sufficient cause of abortion, and cases enough are on record to prove that it is so. But it would appear that unless the degree of violence is such as to endanger the life of the mother, it is not likely to occasion abortion. "In 1811 a man was executed at Stafford for the murder of his wife. She was in the pregnant state, and he had attempted to induce abor- tion in the most violent manner, as by elbowing her in bed, rolling over her, &c., in which he succeeded — not only procuring abortion, but along with it the death of the unfortunate woman."' * "A female in the last month of her pregnancy was struck on the abdomen by her husband. An extensive detachment of the placenta caused the immediate death of the foetus, and that of the mother in fifty-one hours afterwards." f Severe injuries not directly inflicted on the abdomen often fail of occasioning abortion. Thus, Madame La Chapel le mentions the case of a young midwife, who was pregnant and had a narrow pelvis ; and who, with a view to procure abortion and avoid the Caesarian section, threw herself from a height. She died in consequence of her wounds, but she did not miscarry. Mauriceau also gives the case of a preg- nant female seven months gone, who to escape from a fire in her room slid down from the third story, but losing her hold from fright, fell upon the stones and fractured her forearm ; but there was no abortion. The same remarks apply to the introduction of instruments into the womb, as to the causes of abortion which have been already mentioned. In some instances abortion has been procured ; in others, though con- siderable injury has been inflicted, the child has been born alive ; and in all of them the mother's life has been endangered or sacrificed. In attempting to puncture the membranes, especially at the early periods of gestation, the uterus has generally been seriously, and often fatally, injured. Sulphuric acid^ in one extraordinary case, has been injected into the vagina with a view of producing abortion. The result was the most * Smith's ' Forensic Medicine,' p. 305. f Campbell, op. cit. p. 131. 74 FCETICIDE. violent inflammation of the parts, and adhesion of the os tincoe, with the formation of a dense membrane over it. After attempting delivery by incisions into the neck of the uterus, it was found necessary to per- form the Caesarian operation — and both the mother and the child died.* The following case which occurred in the practice of Dr. Wagner, of Berlin, illustrates so forcibly the difficulty of procuring abortion in women not predisposed to miscarry, whether by medicines or by mechanical means, that it will form a very fitting conclusion to this subject. •'A young woman, seven months with child, had employed savin and other drugs with a view to produce miscarriage. As these had not the desired effect, a strong leathern strap (the thong of a skate) was tightly bound round her body. This too aA-ailing nothing, her paramour (according to his own confession) knelt upon her, and com- pressed the abdomen with all his strength : yet neither did this effect the desired object. The man now trampled on the girl's person while she lay on her back ; and, as this also failed, he took a sharp-pointed pair of scissors, and proceeded to perfoi-ate the uterus thiough the vagina. Much pain and haemorrhage ensued, but did not last long. The woman's health did not suffer in the least ; and, pretty much about the regular time, a living child was brought into the world without any marks of external injury upon it." Examination of the Female. — In cases of abortion we may be re- quired to examine the person of the suspected female. We should be guided in such an examination by the signs already laid down at p. 59 ; bearing in mind that these signs will of course be less strongly developed in the early than in the later months. Before two months little dependence can be placed on these signs. If the female dies, we may be required to examine the body, and must be guided by the same signs that exist in delivery at the full period, but which are less distinct as the period of utero-gestation is earlier. The following is a summary of the chief points to be attended to in cases of abortion : The supposed product of conception must be sub- mitted to minute and careful examination. If a foetus has been ex- pelled, its age must be determined by the rules already laid down. The reputed mother, whether alive or dead, must then be examined ; - — if alive, we must endeavour to ascertain whether there was or was not such a predisposition to abortion as to account for its having taken place, without attributing any great efficacy to the means employed. With a view of determining whether or not such a predisposition exists, we must inquire into the general state of health of the mother before the abortion took place, and especially whether she has had previous abortions — and if so, whether they occurred at or about the same period of gestation. If the female died from the means employed, we * This case is given in the report of M. Guerin to the Academie Natiouale of Paris, and is cited in the ' Lancet/ voL viii. p. 38. SUMMARY. / O must use the same caro in examining the state of the uterus, and must observe the rules hereafter to be laid down for conducting post-mortem examinations. Some questions of medical ethics mix themselves up with the question of abortion, as Under what circumstances, and by what means, is it morally and legally proper to induce premature delivery % and what circumstances will justify the Ccesarian operation ? Such questions as these are easily ai^wered. The medical man is clearly justified in resorting to any measures which promise to pre- serve the life of mother and child when both are threatened ; and where one only can by any possibility be preserved, the female herself may use her right of self-preservation, and choose whether her own life or that of her child shall fall a sacrifice to the means recommended to be used. INFANTICIDE. There is no crime which meets with so much public sympathy as Infanticide, and this feeling has been largely shared by members both of the medical and legal profession. The medical man hcis conse- quently been led to take the part of an advocate where he should have been mei-ely the man of science ; while the lawyer has equally for- saken his proper sphere by setting himself up as a judge of matters with which he could have but a slender acquaintance. This misplaced humanity, added to learning equally misplaced, has encumbered with objections, and overlaid with refined subtleties, a subject necessarily complicated. The public sympathy for the child-murderer arose out of the ex- treme harshness and cruelty of a former statute (21 Jac. I. cap. 27), which virtually visited the concealment of shame with the punishment of murder. Dr. William Hunter, under the influence of that injus- tice, wrote, in 1783, his celebrated essay ' On the Uncertainty of the Signs of Murder in the Case of Bastard Children.' About a quarter of a century later (1803) an act was passed decreeing that women accused of infanticide should be tried by the same rules of evidence as obtain in other trials for murder ; but that the prisoner, if acquitted, may be put on her trial! for concealment of the birth, and, if found guilty, punished by imprisonment for a term not exceeding two years. The provisions of this statute were confirmed by an act passed in June, 1828 (9 Geo. IV. cap, 31), which act also provides that it shall not be necessary to prove whether the child died before, at, or after its birth ; but that if any woman tried for the murder of her child shall be acquitted, she may be tried for the concealment of the birth, and punished as if she had been originally put upon her trial for the con- cealment of the birth. Questions of infanticide are necessarily more complicated than those 76 INFANTICIDE. of homicide in general ; for, previous to the inquiry into the means by which a child has come by its death, it is necessary to show that it has been born alive. The medical man may, moreover, be required to examine the female suspected of being the mother of the child, in order to determine whether or not she has been recently delivered. Two classes of questions, then, may be raised in cases of infanticide ; the one relating to the child ; the other to the mother. QUESTIONS RELATING TO THE CHILD. These are the following : — 1. What is the degree of maturity of the child ? 2. Was the child bora alive ? 3. If born alive, how long did it survive its birth ? 4. How long has the child been dead ? 5. What was the cause of death ? 1. THE DEGREE OF MATURITY OF THE CHILD. This question will be answered by employing the data contained in the introduction to this Chapter, viz., the length and weight, the position of the centre of the body, the proportional development of the several parts, the growth of the hair and nails, the condition of the skin, the presence or absence of the membrana pupillaris ; in the male, the descent or non-descent of the testicles, &c.* 2. WAS THE CHILD BORN ALIVE? This question involves a great number of details, and depends on the determination of many difficult and delicate points. First, as to the legal meaning of the term bom alive. It has been decided in more than one case, that to constitute live-birth the child must be alive after the whole body has been brought into the world; that it must have an independent circulation ; but that to constitute such independent circulation, it is not necessaiy that the umbilical cord should be severed. In examining the body of a child with a view to determine whether or not it was born alive, the chief point to be attended to is the state of the lungs. If we can discover in these organs signs of respiration, we establish a probability in favour of live-birth ; but if there are no signs of respiration in the lungs, there is an equally strong probability that the child was still-born. But in the absence of all signs of respira- tion thei'e may still be sufficient proof that a child has or has not been born alive. Hence the present inquiry consists of two parts. 1. The evidence of live- birth, independent of, and prior to, respira- * See ante, p. 63 et seq. INTRA-UTERINE MACERATION. 77 tion. 2. The evidence of live-birth deduced from, and subsequent to, respiration. The evidence of live-birth prior to respiration is either negative or positive, — negative when we discover signs of previous death within the womb ; and positive when we discover injuries upon the body of the child which must have been inflicted while the blood was still cir- culating, and of such extent and severity that they could not have happened accidentally or been inflicted during the birth. Intra-uterine maceration. — The appearances presented by a child which has died in the womb, and has there undergone maceration, are the following : — The body is shrunken and flaccid in every part, the chest and abdomen flattened, the ribs distinctly visible through the skin, the ilia prominent, the extremities attenuated. The head is soft and yielding, so that it falls flat in whatever position it may be placed. The cuticle is more or less extensively detached, and is everywhere easily separated from the true skin. On the hands and feet the cuticle is white, thickened, and wrinkled, as if from the application of a poultice. The true skin itself is moi'e or less extensively discoloured. The abdomen, which is the first part to exhibit the change of colour, presents a mottled appearance, blending a rose and ash colour. Else- where the skin assumes a brownish red, without any admixture of green. The parts of generation have a deep-red coloui", as have also, in a less degree, the head and face. The umbilical cord is straight and flaccid. The entire surface of the skin is covered with a soapy fluid, so that the body, when handled, slips from the grasp. On cutting into the cellular membrane it is found to be infiltrated with serum reddened by the colouring matter of the blood, and to contain in parts, especially in the scalp, a substance which Oi-fila has aptly compared to gooseberry jelly. The periosteum is easily detached from the bones of the cranium, which are loosely united, and move easily the one upon the other. The several cavities are filled with an abundant sero-sanguinolent fluid ; and the viscera are tinged throughout of a reddish-brown colour, at the same time that their minute structure is very distinctly dis- played. These appearances are more or less strongly marked, as the child has lain a longer or shorter time dead within the womb. They are quite distinct from the effects of putrefaction, whether in air or water, and the odour of putrefaction is entirely wanting. When developed in a marked degree it is impossible to mistake them for those due to any other cause ; but if the death of the child took place only a short time before its expulsion from the womb they would not be present. In such a case the absence of all traces of respiration on the one hand, and of marks of violence accompanied with copious effusion of blood, on the other, would prove that the child was still-born. The single case in which, anterior to, and independent of, the es- tablishment of respiration, we may state that a child has been bora alive, is, when we find marks of violence on the body so severe that 78 INFANTICIDE. they could not have been inflicted during the birth, and attended with haemorrhage so considerable that it could only have occurred while the blood was still circulating. Thus Devergie relates a case of the mui-der of an infant that had not respired, which was proved by the existence of extensive wounds and marks of great violence on the head, with copious effusion of blood.* To justify a positive opinion in such a case, the loss of blood must be large ; for a severe wound in- flicted On a plethoric infant after the circulation had ceased, might be attended with considerable haemorrhage. There are two cases, then, in which, independent of, and anterior to, respiration, we may decide the question, ** was the child born alive?" in the one negatively when we find the marks of intra-uterine maceration, in the other affirmatively, when we discover injuries Avhich, from their extent and severity, must have been inflicted after the birth of the child, and while the blood was still circulating. But the cases in which we can obtain evidence of live-birth before respiration must be extremely rare, as few children in whom the blood is still circulating are born without respiring, at least im- perfectly. In the great majority of cases, therefore, the evidence of live-birth must be sought for in the lungs, proof of respiration being the first link in the chain of evidence that the child was born alive. In order to prove that a child was born alive we must first show that respiration has taken place ; and then that the child breathed after the birth. For in order to prove that the child has been horn alive, it will not suffice to prove that it has breathed, for it may have breathed during the birth and yet have perished before the delivery was complete. HAS RESPIRATION TAKEN PLACE ? The best evidence of respiration is the change which it produces in the external appearance of the lungs ; and, were it not that inflation gives rise to the same change, a mere inspection of the lungs would supersede all other tests. As it is, it serves to establish the alternative of respiration or inflation when all other means fail. Lungs which have neither respired nor been inflated, are of a uniform texture throughout, and resemble both in colour and con- sistence the adult liver. Their surface is marked by slight furrows, which obscurely denote the division of the lobules. When the lungs are full of blood, these slight furi-ows are scarcely, if at all, visible ; but when those organs are comparatively empty, the furrows are more distinct, and are still more strongly marked in the lungs of the foetus which has undergone intra-uterine maceration. The lungs are also sometimes found studded with small circular melanotic spots. The effect of respiration or inflation varies according to the degree of either. The smallest quantity of air serves to develop some of the • ' Annales d'Hygiene,' May, 1837. DEVELOPED AIR-CELLS. 79 air-cells on the surface of the lungs ; and these developed air-cells form the best proof of the admission of air in one of these two ways. The right lung, and especially the edges and concave surface of its upper lobe, admit the air most readily : it is here, therefoi-e, that the first effects of inflation or respiration must be looked for. The aii--cells thus developed present a highly characteristic appeai- ance. If the lungs are fresh and tilled with blood, their jjosition is marked by briUiant vermilion spots ; if the lungs contain less blood, or if they are examined some days after the death of the child, the spots are of a lighter colour ; and in children who have survived their birth some days, they have very nearly the colour of the healthy adult lung. The form and arrangement of the cells are not less characteristic than their colour: they are angular in shape, are not perceptibly raised above the surface, and are obviously situated in the substance, though near the surface, of the lung. The grouping of the cells is generally irregular, but occasionally, as Devergie Fig. 5. observes, they are found in groups of four, arranged in a perfectly regular and symmetrical manner. The ordinary appearance and grouping of the cells is represented in the annexed wood-cut taken from a coloured drawing of foetal lungs in which respiration had been imperfectly set up. Another appearance which I have once seen the air-cells pi esent, is that of a group of small globules, like millet seeds, arranged closely side by side, and on the same level. The only appearances on the surface of the lungs with which these developed air-cells might by possibility be confounded, are, 1, the small circular melanotic spots already mentioned ; 2, small round spots "of blood thrown out upon the surface ; and, 3, air-bubbles, the product of putrefaction. The first two appearances may be at once distin- guished by the perfect roundness of the spots, the entire absence in them of anything resembling a developed texture, and their character- istic colour, the melanotic spots being black, and the spots of blood deviating very slightly in colour from that of the surrounding portions of lung. These spots, therefore, can occasion no difficulty. The appearance of the air-bubbles produced by putrefaction is, if possible, still more characteristic. The air collects on the surface, and between the lobes of the lungs, either in detached globules, the size of peas, rising above the level of the surrounding lung, or as a string of minute vesicles not unlike a fine mercurial injection beneath tissue- paper. The air is evidently contained in the cellular membrane con- necting the pleura with the surface of the lung, and its true situation is often pointed out by a small globule seated upon a larger one. If these appearances were not sufficient to distinguish air, the product of putrefaction, from air contained within the air-cells, it would suffice to pass the finger over the surface of the lung. The air follows the 80 INFANTICIDE. pressure of tlie finger, and is dispersed, and a little stronger pressure effaces the bubbles, and will even break down the larger globules. No amount of pressure so applied will force the air out of the air-cells, or in any way alter their appearance. Some authors, as will be presently more fully stated, have spoken of an emphysema of the foetal lungs, as giving rise to some difficulty in applying the hydrostatic test ; but it will be shown that this so-called emphysema is merely an incipient process of putrefaction, giving rise to precisely the same appearances, and admitting of the same ready pjg_ Q discrimination, as the more ordinary results of putre- faction. The subjoined engraving is as faithful a representation as it is possible to give, without colour, of the several appearances described in the text. With the exception of the large air-bubbles, which are taken from another subject, all the appearances were present on the same limited space of the surface of the lungs. The air-cells are recognized by their peculiar shape and grouping; the round dark spots are melanotic, the fainter spots are effused blood ; the string of small light round dots, and the two large circular spots, are air-bubbles. It can scarcely be necessary to offer a caution against confounding with the developed air-cells that change of colour which takes place on the surface of fresh foetal lungs from the contact of air. The change of colour is the same in both cases, but the mere contact of air with the surface of the lungs does not alter the texture of the organ in any way. The appeai-ance of the developed air-cells is, therefore, quite charac- teristic. It furnishes undeniable proof either of respiration or of inflation, and is the only lung-test to which no serious objection can be offered. Considered as a test, or sign, of the admission of air into the lungs in one of these two ways, it is also as delicate as it is simple ; for it detects the smallest possible quantity of air introduced into the lungs, a quantity much too small to have any appreciable effect on the specific gravity either of the entire lung, or of the portion of the lung into which it has been introduced. I have repeatedly detected at a glance the existence, in the superficial air-cells, of a quantity of air which was insufficient to render the smallest fragment of the lung buoyant ; and I have never found these signs of respiration absent in any case in which a child was stated to have breathed, though for the shortest space of time. In one case in which it was reported that the child had given only three distinct gasps, the effect of respiration was obvious, at the first glance, in the bright vermilion-coloured groups of developed air-cells scattered over the surface of the right lung. This sign, there- fore, succeeds where the hydrostatic test fails. If a different appearance were produced in the air-cells by respira- tion and inflation respectively, and we could infallibly distinguish the DEVELOPED AIB-CELLS. 81 one from the other, there would be no need of any other lung-test ; and if it could be made to appear that all the other tests which have been proposed fail in effecting this most desirable object, then all those tests would cease to have any claims upon our attention. Devergie,* after stating, correctly enough, that an attentive examina- tion of the bodies of several infants had enabled him to distinguish, d priori, and without any other research, lungs belonging to a still- born infant from those of an infant which had breathed ; and also to determine whether the air had dilated all parts of the lungs, or merely certain portions of those organs, adds, that " in many cases he could determine whether the distension of the lungs with air was the effect of respiration or of insufflation." In the case of air introduced by respiration, Devergie states that there is a minute injection of capillary vessels on the surface of the air-cells, which injection does not take place in the case of inflation. This distinction may be well founded, but it deals with parts so extremely minute, and, according to the author's own statement, is to be relied on only in ma7iy, but not in all cases, that it may be fairly set down as unfit for medico-legal use. I have not myself observed such, a difference between the effects of in- flation and respiration as to pretend to be able in this way to distinguish the one from the other. Developed air-cells, then, form the best, and the only necessary proof, of the admission of air into the lungs ; and they are to be found in every case of respiration or inflation, however limited in extent, or slight in degree. t The number of the air-cells, and the degree to which they are developed, is, moreover, a measure of the extent to which these processes have been carried. When respiration is complete, the lungs present the spongy, crepitant character of adult lungs, and differ from them only in having a more rosy colour. Before proceeding to the consideration of the other lung-tests, it is necessary to premise that respiration is not a sudden, but a gradual process ; that it is rarely, perhaps never, completed in a few respira- tions; that it very often remains incomplete and partial after many hours, days, or even weeks ; and that in some grown-up persons portions of the lungs are even believed to remain permanently in their fcetal state. In by far the majority of cases of infanticide, therefore, we shall have to deal with lungs in which the process of respiration has been very incompletely set up. This fact increases the importance of a sign which stands us in stead where, as will be presently shown, every other test may fail. But the admission of air into the air-cells of the lungs is not the only efl'ect of respiration. As a general rule, this change is accom- * ' Medecine Legale,' vol. i. art. Infanticide. t It is strange that this simple sign of respiration should have been so often overlooked. Cruveilhier, in his ' i^Jorbid Anatomy/ depicts the bright ver- milion air-cells as a disease of the foetal lungs. G 82 INFANTICIDE. panied by an increased afBux of blood, leading, as a natui-al conse- quence, to an increase of weight in the lungs themselves, and an in- crease in their weight as compared with that of the body. This increase of weight, absolute and relative, has been made the basis of two lung-tests. The absolute Weight of the Lungs. — This test of respiration rests upon the supposition that " the arteries and veins of the lungs of a foetus, which have not respired, are empty, and in a state of collapse," whilst after respiration they become more or less filled with blood. This erroneous statement of Fodere has been corrected by Orfila and Devergie. That it is a gross mistake, I have had many opportuni- ties of proving ; for I have examined lungs which had breathed, and found them almost destitute of blood ; and have repeatedly met with lungs that have never admitted air, or which presented only a few groups of developed air-cells, but yet were gorged with blood in eveiy part. The received estimates of the weight ot the lungs before and after respiration were in accordance with these erroneous assumptions. The lungs of mature children before respiration were stated to weigh one ounce, or 480 grains, and after respiration two ounces, or 960 grains. How remote these estimates were from the truth, the following averages, founded upon upwards of 400 observations on mature children, will serve to show : — Still-born, 874 grains ; children who had survived their birth one month or less, 1072 grains. The observed weight, therefore, in still-born children is nearly double the rude estimate of authors, and the increase after respiration, instead of being equal to the original weight, is less than one-fourth. These averages differ too little from each other to admit of practical application in a court of law : the extreme figures are still more conclusive, as the comparison instituted in the following table will show.* Before After Before After Respiration. Respiration. Respiration. Respiration 510 510 694 — 520 — 703 — 550 546 713 726 562 744 746 586 590 — 774 630 (two) — — 861 632 — 920 640 — 1054 1000 647 — — 1173 658 — — 1189 666 — — 1203 683 675 1480 687 — 1950t — * For the particulars of these observations, which are all taken from English sources, see ' Lancet,' Oct. 1, 1842. The case marked f has been subsequently added. It is given on the authority of Dr. A. Taylor. r STATIC TESTS. ABSOLUTE WEIGHT OF TH] Before After Eespiration. Respiration. Maximum . 1950 1203 Minimum 510 510 Mean . 769 820 83 This table speaks for itself: it shows in a striking manner the limited application of the absolute weight of the lungs as a test; for, out of 34 cases, there is not a single one in which we could have stated, by means of this test alone, that respiration had, or had not, taken place ; while, in two instances, the great weight of the lungs would have led us to infer respiration, though the children were still-born. As in the great majority of cases of alleged infanticide the lungs of the child, if it has breathed at all, are found to contain but little air, it is important to determine the effect of imperfect respiration in in- creasing the weight of the lungs. The following is the average result of a considerable number of facts : — Still-born, 874 grains ; imperfect respiration, 988 grains; perfect respiration, 1195 grains. The effect of imperfect respiration, then, is to increase the weight of the lungs by about 100 grains, or one-eighth of their original weight. The mean weight of the lungs after different durations of respiration is as follows : — Still-born, 874 grains; less than one hour, 918 grains ; twelve hours, 853 grains; one day, 1000 grains ; one month and less, 1072 grains. Hence the duration of lespiration for one hour adds less than 50 grains to the weight of the lungs, which is increased by only 126 grains when respiration has lasted one day. If additional evidence were required of the uselessness of this test, it might be found in a comparison of the weight of the lungs in two children born alive in whom the weight of the body was the same. In the one case the lungs weighed 1544 grains, and in the other 494, the one being more than three times as great as the other. It appears, then, that the difference between the absolute weight of the lungs before and after respiration, and especially after imperfect respi- ration, or respiration lasting only for a short time, is much too slight to be used as a test ; and that the inference drawn from a comparison of average weights is fully confirmed by a comparison of the extremes. This test, moreover, is rendered unnecessary by the mere inspection of the lungs ; unless, indeed, it could be shown that the absolute weight of the lungs promises to assist us in distinguishing respiration from inflation. This, though it has been recommended for that purpose, it does not do; for as it fails in distinguishing the lungs of the still-born from those which have respired, it must also fail in distinguishing lungs that have breathed from those that have been inflated: for inflated lungs are, as to the blood which they contain, in the condition of foetal lungs. Ploiccquet's Test, or the ratio of the weight of the lungs to that of the body. — Before entering upon an examination of this test it is ne- 84 INFANTICIDE. cessary to premise, that the bodies of still-born children are heavier by about one-third than the bodies of children born alive ; that the body of the male is heavier than that of the female ; that the proportion which the weight of the lungs bears to that of the body decreases as the weight of the body increases ; and that the weight of the lungs is subject to much greater variation than that of the body. This test is a good example of the futility of all conclusions drawn from a small number of facts. Ploucquet himself making use of three facts, only two of which were strictly comparable, obtained the propor- tion before respiration, of 1 to 70 ; after respiration, of 1 to 35. The moie numerous facts collected by subsequent observers have gi-eatly modified these proportions, and the following statements will, it may be hoped, serve to consign the test to oblivion. The averages drawn from more than 400 observations on mature children are as follow : — Still-born 1:57, instead of 1:70 ; children who have lived one month or less 1:38 instead of 1:35. The extremes, which, as before observed, are the values really required for practical purposes, are shown in the following table. Before After Before After espiration. Respiration . Eespiration. Respiration. 1:91 — 1:54 1:55 1:82 — 1:51 (two) 1:52 1:74 — 1:49 1:49 1:71 (two) — — 1:48 1:70 — — 1:46 1:67 1:65 1:45 1:45 1:61 1:61 — 1:44 (two) 1:60 — — 1:41 1:59 1:59 — 1:39 1:57 (three) 1:56 1:21 Before After Eespiration . Respiration Maximum . 1:21 1:39 Minimum . 1:91 1:65 Mean . 1 :60 1:50 The results of this table differ somewhat from those already obtained in the case of the absolute weight of the lungs; for iii 7 cases out of 33 there is certainly a probability, derived from the low ratio obtained, that respiration had not taken place ; but, on the other hand, there is one case in which, relying upon this test, we should have mistaken a still-born child for one that had breathed. The value of our conclusion must, moreover, depend, as in the case of the absolute weight of the lungs, upon an assumption that we have found the true limits both before and after respiration. HYDROSTATIC TEST. 85 The following are the mean proportions after different durations of respiration: — ytill-born, 1:57; less than one hour, 1:51; 12 hours, 1:53; 1 day, 1:48 ; 1 month, or less, 1:38. The difference between the several proportions is here extremely- small ; certainly much too small to justify the employment of the test in cases of imperfect respiration, in which alone such a test can be required. If further proof were required of the futility of this test, it might be found by comparing the ratio of the lungs to the body in two cases in which the weight of the body was precisely the same. Thus, to take only one instance : the weight of the body being in each of two children born alive 32,436 grains, the lungs bore to the body in the one case the proportion of 1 to 21, in the other of 1 to 66 ; the one ratio being more tlian three times as great as the other. Precisely the same re- marks, too, apply to this test as to the absolute weight of the lungs. Simple inspection would render it superfluous even if it were useful ; and it cannot serve to distinguish inflation from respiration. Both the static lung-tests should, therefore, be allowed to fall into disuse as alike unsafe and unnecessary. The Hydrostatic Test. — This is without exception the most interest- ing and important test ever proposed for the determination of a medico- legal question ; interesting from the many controversies to which it has given rise, and important on account of the purpose to which it is applied, and the high value formerly assigned to it. That this test may be understood, it must be premised, that though, when first proposed, it was erroneously considered a test of live or still- birth, it is merely a test of respiration; the question, when or where did respiration take place, being consequent on the determination of the fact of respiration. It is necessary further to premise that the Hydrostatic Test has undergone several modifications since it was first proposed towards the end of the seventeenth century. Originally, and till a comparatively recent period, it consisted in placing the lungs, with or without the heart attached, entire in a vessel of pure water of the temperature of about 60°. This rough test was first modified to the extent of dividing the lungs into several pieces and experimenting with those pieces as with the entire lungs. The test, as now performed, consists in first immersing the several portions of the lungs in water, and then applying to them the subsidiary test of pressure. It will be presently seen that the objections urged against the hydrostatic test apply chiefly to the test as originally performed ; and that this addi- tional test of pressure removes at least one objection, though it leaA'es others in full force, and opens an important inquiry as to the distinction between the effects of respiration and inflation. In examining the hydrostatic test, it will be convenient to consider, in the first place, the value of the test as originally performed, in- cluding the addition subsequently made of dividing the lungs into several portions, but without submitting them to pressure ; and with 86 INFANTICIDE. the distinct understanding that it can in no case be a test of live-birth, but only of respiration. A supporter of the hydrostatic test would assert on its belialf, that, if the lungs, whether entire or divided into portions, when placed in a vessel of water sink to the bottom, respira- tion lias not taken place. To this assertion there are two objections. 1. That respiration may have taken place, and yet the entire limgs, as well as the several parts into which they have been divided, may sink in consequence of disease. 2. That respiration may have taken place, but to so limited an extent, or in so imperfect a manner, that both the entire lungs and every portion of them, though perfectly healthy, containing only the ordinary quantity of blood, and presenting no unusual appearance, may nevertheless sink. Now, in examining the first objection, it must be borne in mind that disease may exist before respiration or supervene after it. If a disease existing before biith affect the whole of both lungs, it is obvious that respiration cannot take place ; but if it affect only certain parts of the lungs, there is nothing to prevent the healthy portions from receiving air, and those portions of the lungs would float, pro- vided the quantity of air admitted into them were sufficient to render them buoyant, if, on the other hand, the disease supervene after respiration, it is not probable that it would proceed to such an extent as to consolidate the whole of both lungs. Hence some portions would be found to float. On either of the foregoing suppositions, that is to say, whether the disease occurred before respiration or supervened upon it, the cases must be extremely rare in which the objection on the score of disease would be valid. Without having recourse to authorities, it may be safely stated, that disease occurring after respiration rarely, if ever, affects the whole of both lungs ; certain portions, therefore, will remain free from disease, and, provided respiration has been completely performed in those portions, they will, by their buoyancy, at once remove the objection. It will not, perhaps, be safe to deny the possibility of the lungs being so extensively affected by pneumonia as that no part of them shall remain buoyant ; but the event must be of extremely rare occurrence, and the objection will almost never find place. When the disease is partial, whether it occur before birth or after respiration, the objection can hold good only in those cases in which respiration has been so imperfectly established in the healthy portions of the lung as not to render any one of those portions buoyant. In such cases the first objection merges in the second ; for if lungs healthy in all their parts may respire without becoming buoyant, it follows that lungs which have only certain parts of their structure in a sound state may receive air into those parts in a quantity too small to cause them to float. If it can be shown that lungs healthy in all their parts may, in spite of respiration, sink when placed in water, it will follow that lungs which are only,' partially healthy may also sink, though HYDROSTATIC TEST. OBJECTIONS. 87 respiration have taken place. This leads to the second objection, viz. : — That respiration may have taken place, but to so limited an extent, or in so imperfect a manner, that neither the entire lungs, nor any portion of them, though perfectly healthy, containing only the usual quantity of blood, and presenting no unusual appearance, shall float. A single case, reported by Dr. Alfred Taylor,* will suffice to prove the validity of this objection. The child was a female twin, weighing little short of five pounds and probably nearly mature. " The substance of the lungs was healthy, of a deep Modena-red colour, with here and there patches of a somewhat lighter hue. There was no crepitation under the knife, nor was there any mai-k of congestion ; for no more blood followed the incisions than is ordinarily witnessed in dividing the lungs of the foetus." " The lungs were separately placed in water ; but they both sank with equal rapidity. Each lung was then cut into fifteen pieces." " The pieces of the two lungs having been kept apart, were placed in water separately ; and it was remarked that every portion sank rapidly to the bottom : and on com- pression below the surface of water, no bubbles of air escaped." This child had survived its birth twenty-four hours. This single case is sufficient to establish the validity of the objection now under consideration ; but it is by no means unique^ for similar instances have been reported by Bernt, Remer, Orfila, Daniel, Schenk, and Osiander, which cases are quoted in the Essay from which the foregoing fact is taken. Billard meeting with some of these cases was led into the strange error of supposing, that children may survive their birth for hours, and even days, without breathing. f I have myself repeatedly examined lungs in which the process of respiration had been very imperfectly set up in several portions of one or both lungs, and yet only one or two of the several parts into which the lungs were divided floated when placed in water ; but I have not met with any instance in which every portion of both lungs sank. The objection, then, to the statement that the sinking of the lungs, whether entire or divided into several portions, is a proof that respira- tion has not taken place, is a sound and valid objection to the hydrostatic test in its original form ; and the objection of course applies equally to lungs healthy in all their parts, and to those which have only some portions of their structure fi-ee from disease. Let it now be supposed that the entire lungs, or any one of the several portions into which they have been divided, float when placed in water ; and that this buoyancy of the whole lung, or of its parts, is asserted to be a proof that respiration has taken place. This assertion would be met by three distinct objections. The buoyancy may be due, not to respiration, but 1. to Emphysema ; 2. to Putrefaction ; or, 3. to Inflation. The first objection, that the lungs may float in con- * ' Guy's Hospital Reports,' No. v. case 4. ■f • Maladies des Enfans,' title Viabilite'. 88 INFANTICIDE. sequence of emphysema is easily disposed of. The term emphysema, in its usual acceptation, means an enlargement or rupture of the air- cells, which enlargement or rupture can only be produced by air in- troduced through the air-tubes in the process of respiration, or by inflation. Now, air so introduced into the lungs will expand the air-cells so as to furnish, independent of the emphysema itself, distinct proof that the child has breathed. On the other hand, if the emphy- sema were caused by inflation, the first objection would become identical with the third. But the emphysema spoken of as an objec- tion to the hydrostatic test, is an emphysema of a different kind, and is alleged to be caused by air generated in the lung by some peculiar action of its tissues. Dr. Cummin* says : " It sometimes happens that infants sufler violence in the birth ; the labour, perhaps, being tedious, and the mother malformed. The sides of the chest may be so pressed against the substance of the lungs as to do those organs injury ; they become inflamed and puffy, containing air in large vesicles on their surface, and this is what some authors call emphysema." Lecieux also states that in extracting an infant by the feet, he often found that a part of the lungs floated, though the child had certainly not breathed, and even died in the course of the delivery. He could not attribute this accidental buoyancy of the lungs to putrefaction, because the infant did not present the characters of putrefaction, and he examined the body a short time after the extraction ; but as we sometimes see a wound or a bruise, especially on the head, accompanied by an emphy- sematous swelling, it appeared to him that in this case, during the extraction of the foetus, the lungs suffered a sort of contusion ; that an effusion of blood took place into their tissue, which by undergoing a change gave rise to the formation of some bubbles of air, and in this way produced the buoyancy of a part of the lungs. This e?:planation appeared to him the more probable, inasmuch as the lungs had a brownish violet tint.f That it is not necessary to I'esort to this explanation of the forma- tion of gas in the lungs, the following fact will suffice to prove. Duinng the winter of 1840, I examined the body of a mature still-born foetus, within forty-eight hours after its extraction by instruments. There was not the slightest trace of putrefaction in the lungs or in any other part of the body ; there was no change of colour, no softening of tissues, no putrefactive odour, and, with the exception of a vesicle the size of a pea on the surface of one of the lungs, no formation of gas. The lungs, which were gorged with blood, were extracted, put into a gallipot, and carried in the pocket about two hours ; at the end of which time their entire surface was found studded with vesicles, some of them as large as a pea, and others smaller than a pin's head. Here, then, in the course of two hours a very large quantity of gas * • The Proofs of Infanticide Considered,' by William Cummin, M,D. p. 61. f Lecieux, ' Considerations Medico-l^gales sur I'Jnianticide.' HYDROSTATIC TEST. OBJECTIONS. 89 was developed, though the lungs had certainly undergone no injury in the birth, and no single sign of putrefaction could be detected. This incipient process of putrefaction, for it is nothing less, is not limited to the lungs, but may occur in effusions of blood on the brain (of which I have seen two examples) and in other parts of the body, especially in parts containing an unusual quantity of blood. When it occurs in the lungs they are usually congested, or the seat of pulmonary apoplexy which is apt to occur in children delivered after tedious labours, or extracted by instruments. The considerations now advanced seem, therefore, to justify the opinion that this so-called emphysema is nothing more than' an incipient process of putrefaction. Hence the first objection to the floating of the lungs as a test of respiration merges in the second ; and instead of three objections we have only two ; the formation of air in the cellular tissue inconsequence of incipient or advanced putrefac- tion ; and Inflation. 1. Of the formation of air in the cellular tissue of the lungs in con- sequence of putrefaction. The possibility of the lungs floating in water in consequence of putrefaction has been called in question ; but there is no sufficient reason to doubt that the lungs may become buoyant from this cause. Some experiments which I made during the winter of 1839, will serve to illustrate the origin of the opinion that putrefaction will not cause the lungs to float. In some instances the lungs of still-born children, when placed in water, as soon as they began to give out a putrefactive odour, gradually rose to the surface, where they remained for many days, and then slowly sank to the bottom. In other in- stances, large air-vesicles were formed on the surface of the lungs, but not in sufficient number to render them buoyant ; whilst in others, again, though the lungs gave out a strong putrefactive odour, there was no development of air-vesicles, and no tendency to rise to the surface; nor did they ever become buoyant either in the water in which they had stood, or in clear water. This remarkable difference may perhaps be explained by the quantity of blood contained in the lungs, putrefaction being more readily set up when the quantity is considerable. There is no longer, therefore, any room to doubt that gases de- veloped in the various stages of the putrefactive process may cause lungs which have not breathed to float. This objection to the hydro- static test, as originally performed, is, therefore, a valid objection. 2. Of Inflation. The objection that the lungs may be rendered buoyant by inflation, is also valid, as the possibility of inflation being effectually performed to the extent of causing the lungs to float is universally admitted. From what has been stated, it follows that to the Hydrostatic Test, as originally and till a comparatively recent period performed, and used merely as a test of respiration, there are four valid objections, 90 INFANTICIDE that is to say, two to the sinking of the lungs as a sign that respiration has not taken place, and two to the floating of the lungs as a proof that it has. To the sinking of the lungs as a proof of still-birth there are the objections of disease and imperfect respiration, and to the floating of the lungs as a proof of respiration there are the objections of putrefaction (in its several degrees and stages) and inflation. Such is the value of the hydrostiitic test, in the sense in which that term was used up to the pei'iod of the introduction of pressure as an auxiliary test. The Hydrostatic Test as modified by the addition of Pressure. — The mode of applying pressure is not very material, provided it be not carried to the extent of destroying the texture of the lung. For some purposes the pressure of the finger and thumb under water is sufficient ; but if stronger pressure be required it is best effected by placing the fragment of lung in a clean cloth, and, by the aid of an assistant, twisting the two ends of the cloth opposite ways. It can rarely be necessary to carry the pressure beyond this point, though in some experiments to which allusion will presently be made, the frag- ments of the lungs were submitted to strong ])ressure by treading the cloth which contained them under foot.* A supporter of the hydrostatic test, in this its modern signification, would assert, on its behalf, that if the lungs, both entire and divided into several portions, when placed in water, sink, both before and after being submitted to pressure, fyL respiration has not taken place. The objections to this assertion are the same which apply to the earlier test, viz., disease and imperfect respiration, with this difference, how- ever, that portions of lung containing a large quantity of blood and too little air to render them buoyant, might possibly become buoyant in consequence of a portion of the blood being forced out by the pressure. Hence the sinking of the lungs after the application of pressure affords a stronger reason for supposing that respiration has not taken place. On the other hand, supposing the several portions into which the lungs have been divided, to float both before and after being sub- mitted to pressure, and it is asserted that this buoyancy of the lung is a proof of respiration, do the two objections urged with success against the earlier test, viz., putrefaction and inflation, hold good here also ? The objection on the score of putrefaction falls at once to the ground ; for very moderate pressure of the fingers will expel the air generated by putrefaction, and cause the lungs to sink. It only remains, therefore, to consider the force of the objection, that inflation may cause the lungs to float. * Mr. Jennings of Leamington, after applying pressure in the manner now recommended, and subsequently by means of weights, kneaded the several portions of lung in the palm of the left hand with the thumb of the right. • Transactions of the Provincial Medical and Surgical Association, 1834.' HYDROSTATIC TEST. PRESSURE. 91 That air artificially introduced into the lungs will render them buoyant, there can be no doubt ; but whether the application of pi-essure will serve to distinguish the buoyancy which is due to respiration from that due to inflation is a question that demands very careful consideration. The addition of pressure to the old form of hydrostatic test was first proposed by Beclard, and was introduced into practice in this country by Dr. Alfred Taylor,* and Mr. Jennings,t both of whom employed it as a diagnostic mark. The former concludes from re- peated experiments, " that air, introduced by artificial inflation, may, under all circumstances, be expelled by compression, if the experiment be pz'operly performed, and the pressure continued a sufficient length of time. "I Mr. Jennings states, that " air introduced into the lungs, by artificial inflation, may be expelled by pressure, so that the lungs will sink in water," and on the other hand, that " after respiration, the air cannot be expelled from the lungs without completely breaking down the structure of every part of the organ. Any part, however small, not thus broken down, will continue to float." The A^alue of this test can be decided only by an appeal to facts. Now it is admitted by Dr. Taylor, on the authority of Case III. in the J]ssay already cited,§ " that air, from respiration," (imperfect respiration,) "may, by very moderate pressure, be forced out from divided portions of the organs ;" and, on the authority of Case II., " that there are no satisfactory means of distinguishing artificial inflation from feeble respiration." Schmitt also reports a case in which the middle lobe of the right lung alone floated, and that imperfectly, but it sank again when forcibly compressed. The child had lived twenty-four hours, and artificial inflation had not been used.|| This test of pressure, then, does not distinguish imperfect respira- tion from imperfect inflation. On the other hand, some experiments which I made in the year 1841 prove that lungs completely dis- tended by inflation cannot be made to sink by a degree of pressure short of that which destroys the texture of the lung ; and that lungs so distended with air differ from those which have breathed completely only by requiring somewhat more pressure to make them sink. As this statement is important, an account of one of these experi- ments, in the very words in which it was described from notes made at the time, is subjoined. " I took the lungs of a chfld two months old who had died of marasmus, and the lungs of a foetus, still-born, at eight months. I inflated the foetal lungs completely, and in doing so ruptured the air-cells, and produced emphysema over the entire surface, so that * • London Med. and Phys. Journal,' Nov. 1832, and Jan. and May, 1833. t ' Trans, of Prov. Med. and Surg. Association for 1833.' j 'Guy's Hospital Reports,' No. V, $ The child survived six hours, and breathed very imperfectly. II Schmitt, ' Neue Versuche,' &c. 93rd observation, p. 21t. 92 INFANTICIDE. when I ceased to inflate them the lungs rapidly collapsed. I then took one lobe from the lung of either body, and, placing them together in a cloth, submitted them, by means of an assistant, to strong pressui-e. Both portions still retained their buoyancy. I next stood with my whole weight on the cloth which contained them, and repeatedly stamped upon them, but still both floated though their structure was almost destroyed. I then took a portion from the lungs of both children, distinguishing the lung which had breathed by the darker colour of its central portion, placed them both together in the same cloth, and proceeded as before. After applying pressure by twisting the cloth strongly, both pieces continued to float; they retained their buoyancy even after they were trodden upon, and it was not till they were pounded with the heel, and their structure thoroughly broken up, that the inflated portion sank: the portion of the lungs which had breathed still floated, though imperfectly. On pounding this portion of lung a second time, this likewise sank to the bottom. A second and a third experiment led to the same result, the inflated portion of lung sinking after a less degi'ee of pressure than the portion which had breathed, but the structure being in both portions broken up before their buoyancy was de- stroyed." Another series of experiments was attended with the same result. If, in these experiments, it had happened that a degree of pressure, short of that required to break down the structure of the lung, had caused the inflated portions to sink, while it was necessary to destroy the structui-e of the portions which had breathed before they could be made to sink, we could understand how pressure might become a means of diagnosis : but as the only difference is the degi-ee in which the structure of the lung is broken up, and as, in any given case, we shall have to examine a portion of lung separately, and not side by side with one which we can take as a standard of comparison, it is obvious that this test of pressure is not applicable to medico-legal purposes. It has been objected to these experiments that, having been made upon lungs inflated out of the body, their results do not admit of application to lungs inflated within the body. This objection, of which it is difficult to see the force or validity, has happily been obviated by experiments upon lungs successfully inflated within the body. Two such cases, of which one was reported in the ' Medical Times,' November 30, 1844, were communicated to the author by Dr. Henry Browne, of Manchester, and two similar cases by Dr. F. J. Hensley, were published in the ' Medical Times,' February 8, 1845. In all these cases the children were still-born, and the lungs were extensively inflated ; but they could not be made to sink by pressure till their structure was broken up. The report of Dr. Hensley's cases is enriched by some valuable practical comments by Dr. Arthur Farre, with directions for inflating the lungs of still-born children. HYDROSTATIC TEST. PRESSURE. OTHER TESTS. 93 The only objections, then, to the value of the hydrostatic test as perfected by the addition of pressure, are three : — 1. The lungs may sink, and yet the child to whom they belong have breathed, inasmuch as respiration may have been too imperfect to render any portion of the lungs buoyant. 2. The lungs may sink though respiration have taken place, inasmuch as disease may have rendered them specifically heavier than water. 3. The lungs may float, and yet the child may not have breathed, inasmuch as inflation may render them buoyant, and pressure may fail to distinguish this effect of inflation from that of respiration. In addition to the static and hydrostatic lung-tests, the following tests of respiration have been proposed. Changes in the Size and Shape of the Chest. — The chest- before respiration is stated to be small, narrow, and flattened ; after respira- tion larger, and rounder. This test is not wanted in cases of com- plete respiration, while in imperfect respiration the presumed changes do not occur. It is unnecessary in the one case and useless in the other. C/iange in the Position of Diaphragm. — The diaphragm, before respiration, is stated to be arched and to rise high in the chest ; after respiration, to be flattened and depressed. This sign is open to the same objection as the foregoing. Changes in the Volume of the Lungs. — The lungs are stated to be larger after respiration than before ; this increase of size being de- pendent partly on afflux of blood, and partly on the admission of air. The uselessness of this test will be inferred from what has been already said of the static lung-tests. It also is not wanted when respiration is perfect or extensive, and it is useless in that imperfect respiration by which, as has been already shown, the lungs are not materially increased in size either by the afflux of blood or the admission of air. Changes in the Position of the Lungs. — Before respiration the lungs lie far back in the chest, leaving the thymus and pericardium un- covei'ed, and presenting sharp edges ; after respiration they project forwards, seeming to fill the chest, nearly covering the thymus and pericardium, and having their edges rounded. This is a description of foetal lungs and of those which have fully respired ; but the descrip- tion is not applicable to cases of imperfect respiration ; for, in all the points now specified, foetal lungs closely resemble those that have breathed imperfectly. Changes in the Consistency of the Lungs. — Before respiration the lungs are as dense as liver ; after respiration, spongy and crepitous. When the lungs are found spongy and crepitous, the}'- have, of course, received air; but that air may have been either inflated or respirefl. In cases of extremely imperfect respiration, there is no change in the lungs in this respect beyond the limits of the developed* air-cells. 94 IXFANTICIDE. Weight of the Liver compared with the Weight of the Body. — After respiration a part of the blood which liad circulated through the liver is diverted to the lungs. The liver, therefore, loses weight. Professor Berat, of Vienna, availed himself of this fact to encumber the subject of infanticide with another useless test. All the objections already advanced against the static lung-tests, and all that might be urged against any test whatever, apply to this. Orfila took the pains to submit the value of the test to experiment, and found that the ratio of the liver to the body before respiration was 1 to 19 ; after im- perfect respiration, when alone, if ever, such a test is wanted, 1 to 19| ; after complete respiration 1 to 17§. To all the foregoing tests, then, there is one simple objection, — when respiration is complete they are unnecessary, and, when re- spiration is imperfect, useless ; and they do not distinguish inflation from respiration, which is the only distinction really required beyond that obtained by the first glance at the surface of the lungs. The refinements which some German authors have endeavoured to introduce into the hydrostatic test, by means of balances and graduated jars, like the tests now mentioned, may be safely consigned to oblivion. A careful examination of the lungs themselves is the best, and only necessary means of determining whether or not the lungs have received air through the air-passages. If the air-cells aie found developed we have certain proof of respiration or inflation, and the number of cells so developed is the best measure of the extent to which those processes have been carried. The eye will detect these signs of the admission of air into the lungs where the quan- tity admitted is too small to render any portion of their texture buoyant. This sign, therefore, succeeds when the hydrostatic test fails. The practical directions necessary for determining the question of respiration are, therefore, very simple. Proceed at once to extract the lungs, taking care merely not to injure their texture, or that of the surrounding organs : examine carefully the surface of the lungs, and if that surface is found of a uniform colour, and the substance of a uniform firm texture like that of the adult liver, respiration has not taken place ; but if the surface is found mottled with spots of a bright vermilion, or of a rose colour, and these spots contain developed air- cells, then respiration or inflation has taken place. It appears, then, that the only real difficulty which we encounter in ascertaining whether a new-born child has, or has not, breathed arises out of the resemblance of the effects of inflation to those of respiration. This difficulty, though it cannot be overcome by the use of any lung- test, may be materially lessened by some very obvious considerations. It is now^ generally admitted that the lungs of an infant may be inflated through the mouth, without having recourse to any instru- ment. All that is necessary is to secure the nostrils, te force the DISTINCTION BETWEEN RESPIRATION AND INFLATION. 95 larynx back upon the oesophagus, and to imitate the movements of respiration by the alternate compression and non-compression of the chest. Four instances of such successful inflation are referred to at p. 92 of this work. Schmitt succeeded in more than one instance * in completely inflating the lungs in this way : in two cases so perfectly, " that not even a single point was to be found in either lung into which the air had not penetrated." f Such a complete inflation of the lungs is not readily effected even out of the body ; for I have re- peatedly removed the lungs, and inflated them by the blowpipe, and in no case have I been able to expand the entire texture of the lung without rupturing some of the superficial air-cells, and producing emphysema. There is reason, therefore, to believe that it is not easy, even for an instructed and skilful person, to effect a complete expansion of the lungs by inflation ; and it may be safely affirmed that such com- plete inflation could not be practised by an unskilful person. If, then, it were urged on a trial for infanticide, that the mother had resorted to inflation with a view of preserving the life of her child (for the sup- position that it might be put in practice by a malicious person with a view of criminating the mother is too absurd to be seriously entei'- tained), and it appeared in evidence that the lungs were completely expanded with air, the objection must fall to the ground. But even if the lungs were found very imperfectly distended with air, it would admit of grave doubt whether even this slight degree of distension could be effected by an uninstructed and unpractised female recently delivered of a child. This is a case, too, in which circumstantial evidence would come to our aid ; for to render the plea of inflation by the mother at all feasi- ble, she must have shown in other ways her anxiety to preserve the life of her offspring. She must have made some preparations for her delivery, and must have prepared clothes for her child. In by far the majority of cases of alleged infanticide, no such preparations have been made ; and when they have been omitted, it is not likely that the plea of inflation would make any impression on the jury. It would be still less effectual in that large class of cases in which there is not merely no evidence of due preparation, but the body of the child bears marks of violence. Authors have laid down more than one distinction between the effects of inflation and respiration. Metzger, indeed, gives no less than four diagnostic marks. He states that inflation is distinguished by incomplete distension of the lungs, by flatness of the chest, by the want of crepitation when incisions are made into the lungs, but chiefly by the bloodless condition of the lungs, such bloodless condition not being accounted for by previous haemorrhage. All these distinctions are unfounded ; respiration also produces incomplete distension of the lungs, accompanied by perfect flatness of the chest, absence of crepita- * Op. cit. Experiments, Ixxx. and xcviii,, also x. xliii. and xlix. t Page 189. 96 INFANTICIDE. tion, and a comparatively bloodless state of the lungs. The static lung-tests have also been employed as a means of diagnosis, on the well-founded assumption that inflation does not affect the weight of the lungs. Now as the static lung-tests do not serve to distinguish respiration from non-respiration, and the inflated lungs are, as far as the blood they contain is concerned, in the condition of lungs which have not breathed, it follows that the static lung- tests cannot dis- tinguish respiration from inflation. There is fortunately one available distinction on which but little stress has been laid. In all unskilful attempts to inflate the lungs of a child through the mouth, air is introduced in considerable quantity into the stomach. The absence of air, therefore, from the stomach would go far to prove that inflation had not been practised. Assuming that, by a careful inspection of the lungs, we have con- vinced ourselves that either respiration has taken place or inflation been practised ; and further, that the body of the infant has marks of violence upon it, that the stomach does not contain air, and that the circumstantial evidence, strengthened by the general considerations respecting the difficulty of inflating the lungs, convince us that the alternative of inflation is untenable ; but that the infant must have breathed, a further inquiry is still needed before we can determine the question of live-birth, in the sense which the law attaches to that term. The question still to be answered is : — Did respiration occur before, during, or after birth ? Respiration may take place before complete delivery, a. in the passages ; 6. in the womb ; and c. after the delivery of the head of the child, the body still remaining in the passages. a. Respiration may take place in the womb in cases of face-presenta- tion. Such an event, however, must be extremely rare, for face pre- sentations occur once only in 280 deliveries, (1 in 279f, Churchill). In this position, too, respiration would probably be extremely im- perfect, so that the complete expansion of the lungs would at once negative the supposition of the child having breathed within the womb, and perished before complete delivery. h. Respiration may also occur during the passage of the child through the vagina ; and it is of frequent occurrence during the intro- duction of the hand to facilitate tedious labour, or to effect a change in the position of the child. It must also be admitted to be possible in cases where no manual assistance is given, provided the parts of the mother are capacious. In this class of cases, too, it is probable that respiration would be very imperfectly established, so that the complete distension of the lungs would negative the supposition of respiration having occurred only in the vagina. c. Respiration after the delivery of the head of the child, and before the complete separation of the body from the parts of the mother, is a common event. In such a case no serious impediment is likely to be offered to the complete deliveiy of the child. Schmitt relates no less CONTENTS OF THE STOMACH AND INTESTINES. 97 than nine cases of this kind which occurred in his own practice, and in all of them the child was safely delivered. On the other hand, a few cases are recorded in which children, having breathed in this situation, perished before the completion of the labour ; and the same fatal result may happen to children who have breathed in the womb or in the passages. The possibility of respiration taking place before the complete sepa- ration of the child from the mother is thus placed beyond a doubt ; and it must be evident that the mere inspection of the lungs will not enable the medical man to assert positively that respiration took place before, during, or after the birth. If respiration has taken place to a very limited extent, it may have occurred before birth ; but if the lungs are found fully distended with air we should be justified in assuming that the child was born alive. The examination of the lungs, with a view to ascertain whether respiration has or has not taken place, is not the only means we possess of solving the question of live-birth. We may succeed in obtaining better evidence than the state of the lungs can afford that a child has been born alive, by a careful examination of other parts of the body : — of the stomach, intestines, and bladder ; and of the organs of circula- tion, the umbilical cord, and the skin. The changes in the organs of circulation, in the umbilical cord, and in the skin, at the same time that they are proofs of live-birth, are also means of determining how long a child has survived its birth. The more minute examination of these points will, therefore, be re- served till the indications to be derived from the state of the internal viscera have been considered. The stomach may contain milk, or farinaceous food, proving that the child was born alive, and had survived its birth long enough to have been fed. Milk is readily identified by its physical characters, and by Trommer's test, as used for detecting the presence of sugar in urine.* The farinaceous food may be identified by means of the starch it contains, which strikes with iodine-water a characteristic blue colour ; and by means of the sugar which it contains, if it have been sweetened, the sugar yielding characteristic results when treated by Trommer's test. The presence of blood in the stomach also affords a probability of live-birth, for it is more likely to have been swallowed than to have been poured out as the result of disease. The examination of the intestines may sometimes throw light on the question under consideration. In mature still-born children, the large intestines are found filled with meconium ; and although this may be * Trommer's test. Add to the liquid to be examined a few drops of a weak solution of sulphate of copper, and an 'excess of caustic potass, and apply the heat of a spirit-lamp. The liquid assumes a deep violet tint, and on being heated lets fall a deposit of the red sub-oxide of copper. This test gives cha- racteristic results with the whey and curd of milk, as well as with liquids containing sugar. II 98 INFANTICIDE. partially expelled during labour, a considerable quantity of it will remain in the large intestines in all cases of still-birth. The complete expul- sion of the meconium, therefore, will furnish a strong probability that a child has survived its birth. But, on the other hand, the pre- sence of a considerable quantity of meconium in the intestines must not be taken to prove that the child was not born alive, as its expul- sion is sometimes delayed for some hours or days. Some stress has been laid on the state of the bladder as a sign of live- birth. As this viscus is commonly emptied of its contents soon after birth, its being found empty has been regarded as a pioof that the child was born alive. This sign is not to be depended ui>on, as there is no doubt that the bladder may be emptied of its contents during labour. 3. HOW LONG DID THE CHILD SURVIVE ITS BIRTH? Our means of answering this question are less precise than could be desired. The extent to which res])iration has taken place cannot be depended upon for this purpose ; and recent observations have tended HOW LOXG DID THE CHILD SURVIVE ITS BIRTH? greatly to impair the value of at least one of the three signs just referred to, namely— a. The changes in the organs of circulation; b. The state of the umbilical cord ; and c. The state of the skin. a. Changes in the Organs of Circulation. — There exist in the fcetus certain temporary additions to those organs of circulation which are destined for extra-uterine life. These additions consist of the umbi- lical arteries (a a), which return the blood of the foetus to the mother ; the umbilical vein (6), which conveys the blood of the mother, through the intervention of the placenta, to the fcetus ; the ductus venosus, (c), which conveys part of the mother's blood direct to (/j), the ascending cava ; the ductus arteriosus, (d), which conveys the blood destined after birth to circulate through the pulmonary arteries {kk), direct into (/) the descending aorta ; and the foramen ovale (a Fig. 8), situated at (e), which, by establishing a commu- nication between the right and lett auricle, makes the double heart of the future breathing animal, a single one during the hfe in the womb. All these parts, being unnecessary to extra- uterine life, are closed after birth.* The Umbilical Arteries and Vein. — The obliteration of the arteries takes place much more speedily than that of the vein. At the end of the tirst twenty-four hours they present a marked diminution in their calibre, and an increase in the thickness of their coats near the umbi- licus. At the end of two days the contraction extends through a great part of their length, and at the end of the thii'd day reaches nearly to their termination in the ilie^. The changes which occur in the umbilical vein and in the ductus venosus take place much more slowly. During the first three days a slight contraction only takes place ; on the fourth day this contraction is more marked, and on the fifth it is, with few exceptions, complete. The changes that take place in the ductus arteriosus have been minutely described by Bernt of Vienna, and constitute the Vienna test. This vessel is about an inch in length, imiformly cylindrical, and about the size of the pulmonary artery. After a few respirations the vessel contracts towards the aorta ; but after some hours or days, it resumes its cylindrical shape by becoming uniformly contracted throughout. At the end of a week it has diminished from the size of a goose-quill to that of a crow-quill. On the eighth day the duct is obliterated in half the children, and about the ninth or tenth in all of them. * In the diagram referred to in the text, g g represent the iliac arteries, i the descending cava, and I the vessels of the portal system, derived from the um- bilical vein. 100 INFANTICIDE. The period of obliteration of the foramen ovale is extremely variable. Thus Billard found the foramen ovale obliterated in 1 out of 18 infants of a day old ; in 4 out of 22 children of two days old ; in 8 out of 22 children of three days old ; and 2 in 27 of four days old. De- vergie confiims these observations as to the uncertain period at which the foramen ovale is closed. No precise period can, indeed, be fixed for the obliteration of this aperture ; it often continues open even in the adult, and, in some cases, without producing any dangerous conse- quences. Bernt enters into some minute details respecting the situation of the opening of the fossa ovalis at different intervals after birth ; but these details have no practical value. Indeed, the confidence formerly placed in the closure of the several foetal vessels and of the foramen ovale, as signs of live-birth, and in the order and progress of the pro- cess of obliteration in those parts respectively, as means of determin- ing, with some approach to accuracy, how long a child had survived its birth, has been lately rudely shaken ; for it has been shown that, on the one hand, all the vessels and the foramen ovale may remain open in children who have survived their birth several days; and, on the other hand, that the two parts on the obliteration of which the greatest reliance has been placed (the ductus arteriosus and the fora- men ovale) may be closed within a few minutes after birth, or even, in rare instances, previous to the birth. Of the patency of the foetal vessels after live-birth a good example is given by Mr. Henry Lee, in his ' Pathological and Surgical Observa- "tions,' p. 116. The umbilical vein, the ductus venosus, the ductus arteriosus, and the left umbilical artery, were all open ; the right umbilical artery being closed only near the umbilicus, and yet the child from which the preparation was taken died from umbilical haemor- rhage when a fortnight old, and six days after the separation of the funis. Similar cases have been reported by Jorg and others. That the foramen ovale may remain open at very advanced periods of life is a fact too generally admitted to require proof. On the other hand, the little importance to be attached to the closure of the foetal vessels and foramen ovale is shown by a cafe reported by Dr. Norman Chevers, and illustrated by a preparation exhibited at the Pathological Society, January, 1847. The child had survived its birth only fifteen minutes, and yet the ductus arteriosus was found unilbnnly contracted and so nearly closed as only to admit the shank of a large pin, while its coats exceeded in thickness those of any other of the large vessels. Dr. Chevers was of opinion that in this case the contraction of the vessel took place before birth ; but it is scarcely necessary to resort to this supposition, though the anomalies occasionally met with, and among others the absence of the duct, certainly give some counte- nance to this opinion. Of the very early closure of the foramen ovale, a remarkable case was reported by Mr. Smith, at a later meet- ing of the Pathological Society (December 7, 1847). The child lived sixteen hours and died comatose. Upon examining the body, CHANGES IN THE UMBILICAL CORD. 101 the foramen ovale was found closed bv a strong reticulated membrane firmly attached to its distinct annulus, impervious, and pouched. Dr. Chevers was inclined to the opinion that in this case, also, the closure had taken place before birth. It appears, then, that the fact of the foetal vessels and foramen OA'ale being open is no proof that the child was still-born ; and, on the other hand, that the contraction of the ductus arteriosus and closure of the foramen ovale are quite consistent with a verv short peiiod of survivor- ship. The medico-legal value, therefore, of these tests of live-birth and survivorship is nearly on a par with the static lung-tests. The open state of the vessels will furnish merely a probability of still-birth, and the contraction or closure of one or more of the vessels merely a probability of live-birth. The length of time that the child has sur- vived its birth could certainly not be safely inferred from an examina- tion of the foetal vessels. 6. Changes in the Umbilical Cord. — In a new-born child the umbi- lical cord is fresh, firm, round, and of a bluish colour ; its vessels still contain blood, and its size varies according to the quantity of gelatinous fluid which it contains. The shrinking or withering of the cord is the first change that takes place: it commences at the ligature, and gra- dually extends to the umbilicus. In some cases it begins directly after birth ; in others, not till some hours have elapsed ; it is rarely delayed longer than thirty hours or two days, and never longer than three. The cord is now flabby, and sometimes a distinct redness is perceptible around the umbilical ring. The second change which takes place is the desiccation of the cord. It first assumes a reddish- brown colour, and becomes semi-transparent ; it is then flattened and shrivelled ; and when the process is still more advanced it becomes quite transparent, and of the colour of parchment. The umbilical vessels are distinctly seen contracted, and containing clotted blood, and are sometimps completely obliterated. The commencement of this process of desiccation dates from one or two to four days after birth. The period at which the process is complete varies from one to five days, but the most usual period is three days. The next stage of the process is the falling off of the cord ; this usually happens on the fifth day. Cicatrization of the umbilicus is the last change which occurs, and this takes place about the tenth to the twelfth day. This description is based on the observations of Billard. The changes which take place in the cord of a child born dead, are merely the common consequences of putrefaction. The phenomena of desiccation do not show themselves in the cord of a dead child till after the latest period at which desiccation takes place in the cord of a living child ; and the cord of a dead child does not separate, though the cuticle can be readily peeled off. c. Change in the Skin. — This consists in an exfoliation of the epider- mis, beginning on the abdomen, and extending successively to the chest, groins, axillae, interscapular space and limbs, and, lastly, to the 102 INFANTICIDE. hands and feet. Sometimes the skin comes off in layers or scales, and sometimes in the form of a dust. This process of exfoliation, or des- quamation, of the cuticle, sometimes begins when the child is a day old, sometimes it is delayed till the third or fourth day. It lasts, also, a variable period, — sometimes of thirty days, and sometimes of two months. It continues longest in feeble and delicate children. This, too, is a vital process differing essentially from that separation of the cuticle which takes place in consequence of putrefaction. Al- though the pei-iod of its occurrence is variable, its existence will aflford ciear proof that the child has survived its birth.* The following table, based upon the observations of Billard, pre- sent, at one view, the principal changes just described, with the pro- bable date of their occurrence, and the proportion of cases in which the foramen ovale and ductus arteriosus have been observed to re- main open. Table combining the Changes which take place in the Umbilical Coi-d, with the date of the Obliteration of the several Openings. Days. Umbilical Cord. Foramen Ovale. Ductus Arteri- osus. Umbilical Arteries. Umbilical Vein. Ductus Venosus. 1 Withering. Open per cent. 74 Open per cent. 68 Open. Open. Open. 2 68 59 Obliteration advanced. Open. Open. 3 Desiccating. 64 68 Obliterated. Open. Open. 4 Beginning to separate. , 63 63 Contracted. Contracted. 5 Separation usually complete. 45 52 • • Obliterated. Obliterated. 8 Separation complete. 25 15 10 Cicatrization to commencing. 12 Cicatrization complete. Mucous Exudation. Assuming the two questions — •!. Was the child born alive ? afad, 2. If born alive, how long has it survived its birth ? to have been answered in the affirmative, we may have next to inquire, * Billard, ' Maladies des Enfans,' pp. 13-24. WHAT WAS THE CAUSE OF DEATH? 103 HOW LONG HAS THE CHILD BEEN DEAD? The process of putrefaction differs in no material respect in the adult and in the infant. The same changes occur in the same order. The animal heat is first extinguished, rigidity then comes on, and putre- faction follows. The body of the new-born infant parts with its heat very quickly ; the rigidity is as great, and lasts as long in the infant as in the adult ; and putrefaction, according to Devergie, goes on more rapidly. These facts must be borne in mind when we are deciding the question before us. With the exception of the time required, the principles that will guide us in our decision will be the same at all ages. These will be the subject of a future cha{>ter. The effects of intra-uterine maceration, described at p. 77, must not be confounded with those of putrefaction. The absence of the putrefactive odour will supply a sufficient diagnostic mark. WHAT WAS THE CAUSE OF DEATH .'' There are several ways in which the life of a child which has been born alive may be sacrificed, within a short period of its birth, without any violence being used on the part of the mother, a. It may be so immature or so feeble as to be unable to maintain an independent existence ; h. it may encounter accidental obstacles to the continuance of the respiration ; or, c. it may labour under a congenital disease which will effectually prevent the establishment or continuance of the several vital functions. a. The death of an infant after a few respirations, in spite of the most skilful and persevering attempts to restore animation, is an event too well known to every accoucheur to require proof or illustration in this place ; and such an event must be of more common occurrence in the case of children born under circumstances which preclude any effectual assistance. Among the more common causes of the early death of the infant may be mentioned a long and tedious labour, haemorrhage, and continued interruption to the circulation through the cord; to which may be added the immaturity or feebleness of the infant itself. It ought also to be understood that the same causes which occasion still-birth promote the early death of children bom alive. Thus large children more frequently perish in the birth, or die soon afterwards, than small ones, and male children (as being laiger) more frequently than female children. Again, the danger to the child is greater in a first pregnancy than in subsequent ones. It is probable, too, that in the absence of violence, or even of intentional neglect on the part of the mother, many more illegitimate children would be still-born or die soon after birth than legitimate children. The reports of obstetric practitioners have shown that, while the mor- tahty of legitimate children is about 1 in 20, that of the illegitimate is 104 INFANTICIDE. about 1 in 10 ; while the deaths of males are to those of females as about 7 to 5. b. Among the accidental obstacles to the continuance of respiration may be mentioned, such a position of the infant as shall cause the mouth to be applied to some soft and yielding object, or to be im- mersed in blood, in the discharges, or in water ; and the accumulation of mucus in the mouth, nostrils, and air-passages. It may also be added that there are cases in which respiration is altogethei- prevented, as when the child is born in the membranes. c. The congenital diseases which may prevent the establishment of the several vital processes, or render their continuance for any length of time impossible, have their seat in the three organs most essential to life ; — the heart, the lungs, and the brain. Diseases of the heart and large vessels. — These diseases are rare in infancy ; but malformations accompanied by contraction or early closure of the foetal vessels have an important medico-legal bearing, as affording a presumption in favour of death from natural causes. The diseases of the lungs are more important in relation to the pre- sent question. They are six in number, — 1. Hepatization (red and grey), the consequence of pneumonia occurring before birth. 2. Pul- monary apoplexy. 3. Pulmonary tubercles. 4. (Edema. 5. A disease described by Devergie, under the name of osdema lardaciforme, which seems to be quite as nearly allied to schirrus as to oedema. It affects the thymus as well as the lungs. And, 6. A condition of lung known as atelectasis pulmonum. These diseases of the lungs may affect either their entire structure or a part only. Where the whole lung is involved, it is clear that respiration cannot be perfectly established, and the child cannot long survive its birth ; where, however, the disease is partial, the medical man must state, to the best of his judgment, whether it is extensive enough to prevent the continuance of life. The condition of the lungs to which Dr. Jorg of Leipsig has given the name of atelectasis pulmonum, or imperfect expansion of the lungs, is not, strictly speaking, a disease, but merely an absence of respiration and a persistence of the foetal condition, which is found in by far the majority of new-born children, and may even continue for days or weeks. The substance of the lungs in the unexpanded parts is perfectly healthy, the want of expansion depending probably upon some defect of innervation. The chief diseases which affect the brain and spinal marrow are apoplexy, and accumulations of fluid and morbid softening. The apoplexy of the foetus and new-born infant differ in no respect from the apoplexy of the adult. M. Lasserre (Banking's * Retrospect,' vol. iii. p. 342) gives a case of meningeal apoplexy, a second of effusion of blood into the ventricles, and a third into the posterior part of the left hemisphere. When serum exists to a limited extent either between the membranes or in the ventricles of the brain, life is I DEATH FROM VIOLENCE. 105 not necessarily compromised, at least not within a short period of birth; when, however, the accumulation ot' serum is considerable, it may materially interfere with the functions of" life, and would afford a sufficient explanation of the premature death of the child. The same remark applies to morbid softening of the brain and spinal cord. It must be borne in mind, however, that the brain of the foetus is natu- rally softer and much more vascular than that of the adult. The same remark applies to all the diseases just specified, viz. that they are not of frequent occurrence ; and that when they are present, it is rarely to such a degree as to account for the speedy death of the child, or to have any important bearing on the question of infanticide. It is only when proofs of respiration are present that these signs of death from natural causes have any value ; and in the case of children who have survived their birth but a short time, it may be laid down as a general rule, that the absence of marks of violence affords a fair presumption that death has been due to natural causes. It is true that, in such a case, the child may have been the victim of intentional neglect, and may have died from the want of those simple aids by which the lives of children in more favourable circumstances are pre- served ; or it may have been prevented from continuing to breathe by simply closing the mouth and nostrils ; but the medical man has no means of detecting these causes of death, and the accused must have the benefit of the doubt which attaches to the case. Was the Death due to Violence. — In answering this question we shall have to consider whether the injury which the child has sustained might have been the result of accident. In some cases the traces of injury are so marked and of so undoubted a character, that we may decide without hesitation that they are due to murderous violence. Punctured wounds of the fontanelles, orbits, heart, or spinal marrow, dislocation of the neck, separation of the head from the body, extensive fracture of the bones of the head and face, suffocation by plugging the fauces, or strangulation effected with unusual force, tell their own tale. But there are cases in which the nature and cause of the injury are- only to be determined by reference to obstetric experience and medico- legal experiments, illustrating the mechanical injuries which the child may sustain during and immediately after the birth. Suffocation. — Respiration, as has been already stated, is sometimes prevented or arrested by purely accidental causes which leave no mark of injury on the child ; so that the medical witness has no means of stating whether the child fell into the position of danger, or was intentionally placed in it, or was allowed to remain in it when it might have been rescued from it. This difficulty presents itself in a case of not uncommon occurrence. A child is found in a privy, and the question arises whether it was suffocated by being thrown into it, or expelled while the mother was there for a natural purpose. In such a case, if respiration is found to have taken place extensively or 106 INFANTICIDE. completely there would be a strong presumption against accident. On the other hand, very imperfect respiration would affbid an equally strong probability the other way, provided it can be shown that such sudden and unexpected deliveries do take place. Many cases of sudden parturition in such situations are on record, Thus, J org relates the case of a pregnant woman who " on account of a de.sii-e to evacuate the bowels, went to the night-stool, and brought forth sitting on this, without any pain or bearing down, a large boy, who first struck the edge of the night-stool with his head, and then fell on the ground."* 'I'here was in this case an extravasa- tion of blood on the left parietal bone. Mr. Tatham also mentions the case of a married lady delivered of twins on the night-stool. Jt was not her first labour, but probably her second. Both the children died.t JSuch cases of sudden parturition, though not of very uncommon occurrence, are rare in women who have not previously borne children. It must be admitted, then, as possible, that a foetus found dead in a privy may have been discharged in the course of a sudden delivery, and have died suffocated. Sometimes the child so expelled falls into water instead of into night-soil. In this case, and generally where the body of an infant is found in water, a question will arise whether the child died by drowning, or was placed in the water to conceal some other mode of death. Suffocation by the introduction of foreign substances, such as mud, straw, feathers, wool, and wet linen into the mouth is not an un- common cause of death. In such cases the question arises whether the foreign substcince could have been drawn into the mouth by the act of inspiration, or whether it must have been forcibly and intentionally introduced. No general rules can be laid down for the decision of this question. When a plug of wet linen or other similar material is employed, the mucous membrane is stated to be congested anterior to the situation of the plug, and pale where the greatest pressure has been exerted. Another mode of effecting suffocation is by rolling the tongue back into the throat. As the tongue would probably lesume its original situation, it is not likely that this cause of death would be detected. Strangulation. — A child may be strangled by the application of a cord, and yet no marks of violence appear on the neck. But even where marks of violence do show themselves by a discoloured depres- sion round the neck ; — is it certain that this has been done by the mother ? Might not this appearance aiise from the twisting of the cord around the neck, or by the pressure of the neck of the womb ? Klein, an eminent German authority, has examined this point with great care. He says : " I have never met with an instance of marks of injury of the kind supposed — ecchymoses or suggillations — produced * 'Die GeburtshUmiche Exploration,' p. 116. t * London Medical Repository,' vol. i. part iv. New Series. DEATH FROM VIOLENCE. 107 by the orifice of the uterus, or by the umbilical cord, although I have known a great number of cases in which the neck of the infant had been strongly girded by the funis once or twice twisted round it, strangulation having been either actually produced, or rendered most palpably imminent." He then goes on to speak quite as decidedly regarding the pressure of the neck of the uterus ; not a bruise, as he tells us, nor mark of any kind being left on the infant which has perished in this way. A case mentioned by Jorg shows that the ex- perience of Klein is not to be implicitly trusted : — " The navel string had been twisted five times round the neck, and had left five tolerably deep red impressions." Taufflieb also has reported cases of the same kind,* and there are several English cases on record to the same effect. The presumption in favour of strangulation by the umbilical cord admits of being rebutted in those cases in which the cord is unusually short. It may be stated in this place that the length of the cord is subject to great variety. Though its most common length is 18 inches, it may be as short as 4J inches and as long as 69 inches* (Churchill's 'Midwifery,' 3rd edition, p. 108.) Marks of pressure on the neck, therefore, cannot always be attri- buted to intentional violence ; but as, in most instances, a murderer uses more force than is necessary, it will often happen, in cases of in- fanticide, that the marks are too distinct to be accounted for by the accidental twisting of the umbilical cord round the neck. Moreover, if respiration is found to have been completely established, there will be the strongest presumption against the strangulation having been produced by a cause acting during the birth. On the other hand, the absence from the lungs of all signs of respiration will afford a pre- sumption in favour of the constriction having been due to the um- bilical cord. Strangulation may also be effected by the pressure of the fingers on the throat, in which case ecchymoses may be found corresponding with the cause. Drowning. — The signs of this form of death are the same in the infant and in the adult. These signs will be described in a future chapter. " Fracture of the Skull. — This may happen in three ways: — 1.- In the course of labour. 2. By falls on tihe floor. 3. By intentional violence. 1. The possibility of fracture of the bones of the skull being pro- duced during labour, is proved by more than one well-authenticated fact. Siobold relates a case in which a female with a very narrow pelvis was delivered, by the efforts of nature alone, of a well-formed still-born female child. On examining the head, a great quantity of blood was found extravasated upon the surface of the cranium, and there were three fissures in the left parietal bone, and one in the left * ' Annales d'Hygiene,' vol. xiv. p. 340. 108 INFANTICIDE. frontal bone. INIichaelis of Keil also reports the case of a woman with a well-formed pelvis, who was delivered of her first child after a natural labour. The child breathed both during and immediately after birth, but then died. The head was much disfigured; and on examination, the right parietal bone, which during birth had been directed under the promontoiy of the sacrum, was covered anteriorly and above with effused blood, and on the leraoval of the periosteum was found fractured in five places. The whole of this bone was uncommonly thin. On opening the skull there was found no extravasation beneath the fissures, but the longitudinal sinus was ruptured, and there was an extensive coagulum on the cerebrum on both sides, under the dura mater, and on the tentorium.* These two cases will show the great amount of injury which the head may sustain during birth. Seeing, then, that fracture of the skull during labour is possible, what is the difference between fiactures thus produced, and those the result of intentional violence ? There is no essential difference between the two foi-ms of injury, except in those cases in which unusual violence has been used, the fracture being minutely comminuted and accom- panied by depression ; or the fracture not being limited, as it commonly is when caused by pressure of the womb, to the parietil and frontal bones, but extending to other bones of the skull, and even to the bones of the face. 2. On the subject of fractures of the skull caused by falls on the floor, Chaussier has made some intei'esting experiments. Fifteen still-born children were allowed to fall perpendicularly, and head foremost, from a height of 18 inches on a stone floor. In 12 of them one or other of the parietal bones was broken. When the height was 3 feet and upwards the fractures were proportionably greater. Fractures were also produced by strong pressm-e and by blows.f But Dr. Klein has adduced facts which seem to render it doubtful whether fracture ever occurs in sudden labours from falls on the floor. He availed himself of the opportunities he possessed, by his official station in the kingdom of Wiirtemberg, to procure returns of all such labours occuiTing within his jurisdiction. The result was 183 well-authenticated cases, in 150 of which the mothers were suddenly delivered standing ; yet there was not a single case of death among them, nor of fracture of the skull, or other mischief happening to the infant ; though some of the children had fallen on bare boards, and some on the pavement. The reason of the difference between the ex- periments and those cases occurring naturally is supposed to be that, in the latter, the direction in which the body of the infant is projected is oblique, and the fall is not so instantaneous as in the experimental essay. The truth would appear to lie between these experiments of • These cases are quoted by Eeck, Art. Infanticide. t ' Conside'rations Mddico-l^gales sur 1' Infanticide,' par Lecieux. DEATH FKOM VIOLENCE. 109 Chaussier and the facts collected by Klein ; for Dr. Cohen von Baren has succeeded in bringing together several instances of fracture of the skull from falls in cases of sudden delivery. Out of 50 cases reported by him, 30 children were boi-n while the mother was standing, 17 while stooping or sitting, and 3 while kneeling. Of the 50, 32 were first-born, and 42 were at full term. Of the 19 infants born while the mother was standing, one only had fracture of the skull, and the cause of this was doubtful. But it appears that out of 25 cases in which the cord was ruptured, 5 presented fractui-es of the skull. These fractures of the skull occasioned by falls can also be distinguished from those due to intentional violence only by the comparatively slight injuries sustained in the one case contrasted with the extensive injury commonly inflicted in the other. In cases of fracture of the skull due to a fall during sudden delivery, the umbilical cord is liable to be torn through, especially if it does not exceed, or falls short of, the usual length. The seat of the rupture is usually within one or two inches of the navel. If the umbilical cord, instead of being torn, should be found divided by a cutting instrument, it might be inferred that the injuries to the head were due to accident. In any case, the state of the cord ought to be ascertained. Fracture and Dislocation of the Neck. — These injuries are never present before birth ; and as they are not caused by falls on the floor, they may be taken as sure signs of criminal violence. Contusions. — In examining bruises on the head it is necessary to bear in mind, that tumours commonly result from compression of this part during labour : a mere swelling on the head must not, therefore, be taken for a mark of criminal violence. Incised and Punctured Wounds. — There is nothing peculiar in these wounds as inflicted on the new-born infant. For the distinction between these and other wounds inflicted during life and after death, the reader is referred to the subject of Wounds. Poisoning. — The rules for the examination of the stomach and in- testines, and of the substances contained within them, are the same for the infant and the adult; they will therefore be treated of under the general head of Poisoning. This form of death is rare in the ci\^(i of the new-born child ; but several cases of poisoning by the mineral acids characterized by the same appearances on the body of the infant and on the clothes as mark the action of those acids on the adult, have lately occurred. In all these instances the crime was committed at a considerable interval after the birth of the child. In determining whether an infant has fallen a victim to poison, it should be borne in mind that the alimentary canal, in common with other important oi'gans of the economy, is subject to disease. Sometimes the lining mem- brane of the oesophagus presents a marked injection, in the form of spots, longitudinal lines, or ramifications. These may happen to be arranged transversely and may be mistaken for the effects of a ligature applied to the neck. The stomach, moreover, may be the seat of 110 INFANTICIDE. ulcerations with a sanguinolent, dark-coloured discharge ; and the same changes may be found in the rest of the alimentary canal. Infanticide by Omission. — The omission to tie the umbilical cord sometimes proves fatal ; and there can be no doubt that that omission is in some instances a criminal one. Some authors have doubted the correctness of the general opinion of the necessity for tying the cord, and have adduced arguments in favour of their own view of tlie case. There are, however, facts enough on record to show that such an omission may be attended with danger. Fodere' relates one case in which the child perished in consequence of the ligature becoming loose;* and Dr. Campbell two fatal cases, one from the accidental, the other from the intentional, removal of the cord.f It is probable that fatal haemorrhage would very rarely follow a rupture of the cord, and this probability is strengthened by the testi- mony of Klein. Such a rupture of the cord is not necessarily the act of the mother, for it may occur in cases of sudden delivery taking place in the erect posture. The signs of death from haemorrhage are the paleness of eveiy part of the body, and the small quantity of blood contained in the heart and large vessels. In the absence of wounds to account for the haemorrhage, such a bloodless state of the body may be regarded as in all probability the effect of haemorrhage from the cord. The child may perish by other acts of omission. The mother may have failed to provide proper clothing or food, to remove it from a position of danger, to clear the mouth of mucus, or other accidental impediments to breathing. Supposing it to have been previously shown that the child had survived its birth for some days, death from want of food would betray itself by the great emaciation of the whole frame, and the empty state of the alimentary canal. In these cases the child is at the same time often exposed to the action of cold, which form of death is characterized by pallor of the surfiice, with congestion of the internal parts. Such cases of infanticide by omission being difficult of proof are never punished with death, but the mother is convicted of the lesser crime of concealing tne birth ; and even when marks of violence are found on the body, the inquiry generally assumes so complicated a shape, that the jury cannot be induced to return a verdict of wilful murder. EXAMINATION OF THE MOTHER. The fii"st inquiry with reference to the female suspected of having given birth to the child is, — Whether she has been recently delivei(;d. and if so, whether the period of her delivery corresponds with the • Vol. iv. p. 515 • vol. IV. p. 515. f 'Introduction to the Study and Tractico of Midwifery,' p. 151. DIRECTIONS FOR MEDICO-LEGAL EXAMINATION. Ill time at which the child is supposed to have been born. This part of the inquiry belongs to the subject of delivery (p. 59). Another inquiry may be necessary in certain cases ; and that is into the state of the mother's mind. Puerperal insanity is by no means a rare disease, and there is no doubt that it sometimes takes the form of homicidal mania, threatening the life of the child. An interesting case of this kind is quoted by Paris and Fonblanque.* It was that of a married woman, of good reputation, who being delivered of a child, and not having slept many nights, fell into a temporary frenzy, and whilst alone killed her infant; but company coming in, she told them that she had killed it, and there it lay. The good reputation which the woman had previously borne, the long want of sleep, and the entire absence of the usual motives to the commission of such a crime, added to " many circumstances of insanity appearing," led to her acquittal. Dr. Paris observes, in reference to this case, that " had this woman been of doubtful character, though innocent, she might have been executed for want of medical evidence to prove the nature and frequency of puerperal insanity." A question of some importance in its bearing on infanticide, and having reference to the mother, relates to the strength which a female recently delivered possesses. There is no doubt, that, as a general rule, a woman recently delivered possesses the strength requisite for the destruction of her child's life. Thus, Fodere relates the case of a French widow, who being seized with labour pains while receiving a visit from eight of her neighbours, complained of colic, and seating herself on a bucket in bed, as soon as the child's head passed the vagina, squeezed it flat by compressing it with her thighs. That a woman has strength enough to move about and exert herself after her delivery, is proved by the successful concealment of the fact of de- livery and of the dead infant in the large majority of cases brought to trial, as well as by well-authenticated instances of females walking several miles, or resuming laborious occupations on the very day of their delivery. This subject of infanticide will be best brought to a conclusion by the following summary of the chief points to be attended to in cases of infanticide. 1. Examine the body of the child in order to determine its degree of maturity ; for this purpose, weigh and measure it, ascertain the position of the centre of the body, and attend to the several points comprised in the description of the growth and development of the foetus (p. 63). Note also any malformation which may be present. 2. Note the several circumstances by which the time that has elapsed since the death of the child may be determined, such as the presence or absence of animal heat and rigidity, the existence or non- existence of putrefaction, and, if putrefaction be present, the degree to which it has advanced. * ' Medical Jurisprudence,' vol. iii. p. 129. 112 INFANTICIDE. 3. Examine the entire surface of the body with a view to ascertain the presence of marks of violence, and, if any be present, determine whether they might have been produced during birth, or by accidental causes acting after birth. Examine the mouth for foreign bodies intro- duced into it, and the fontanelles, orbits, heart, and nucha?, in search of wounds inflicted by pointed instruments. Note the state of the umbilical cord, measure it, and ascert'iin whether it has been torn or cut ; and observe the condition of the skin. 4. Open the chest, and remove the heart, lungs, and thymus gland. Separate the lungs, and carefully inspect their surface. Observe whether they are of a uniform liver-colour and compact consistence throughout, or uniformly spongy like the adult lung, or mottled with developed air-cells, as in imperfect respiration. If there are any parts of a lighter colour than the rest, observe whether the structure of the lung itself is developed in those parts, and distinguish the developed air-cells from air contained beneath the pleura, the result of incipient or advanced putrefaction, by applying gentle pressure with the finger. In lungs which are free from putrefaction, the hydrostatic test may be resorted to, to ascertain the degree of buoyancy of the lungs, as a measure of the quantity of air which they contain. o. Examine the heart and blood-vessels ; the foramen ovale, the ductus arteriosus, the ductus venosus, and the umbilical arteries and vein. Observe whether these several parts are contracted or obli- terated, and to what extent and degree ; and whether they contain much or little blood. 6. Examine the stomach to ascertain whether the child has been fed, using for this purpose the tests for sugar, milk, and starch ; if there is any appearance of inflammation in the alimentary canal, test its contents with a view to the discovery of poison. Note whether the intestines contain meconium and in what quantity, and whether the urinary bladder contains urine. 7. Examine the bones of the skull both at the vertex and base, in search of fractures. Inspect the brain and its membranes, and note any effusion of blood or serum. Examine the spine and spinal cord with a view to the discovery of dislocation or fracture of the' vertebrae. 8. Examine the suspected female in order to ascertain whether she has been recently delivered, and how long. It may be necessaiy, also, in certain cases, to inquire into the state of the woman's mind. It is notorious that the law, as it now stands, is altogether in- operative, and that the only punishment really awarded to the child- murderer is the two years' imprisonment with which it visits the concealment of the birth. This impunity is due to the unnece!>sary refinement of the law, which requires at the hands of the medical man a distinction that, in most cases, it is out of his power to make. The child must be bom alive, and unless the medical witness can prove that it has been bom alive, it may bear on its body the SUGGESTIONS. 113 clearest marks of murderous violence, and yet the murderer may escape unpunished. In most instances, the crime of infanticide is committed so soon after the birth of the child, that the only proof of its having been born alive is that furnished by the presence of the signs of respira- tion. But it has been already shown that respiration may take place before and during the birth, as well as after it ; and, in by far the majority of cases, all that the medical man can succeed in proving is, tliat the child has or has not breathed. It is not in the nature of things possible that he should say whether respiration, if it have taken place, occurred before or after the birth. Now, it may be fairly asked. Why require proof of live-birth at all ? for it is notorious that this question does not lead to the punishment, but to the escape, of guilty persons. The suggestion which we would make is this: Let the law be so framed as to exclude as much as possible all appeal to scientific authority. If the child-murderer is to be punished, all question as to the child being horn alive must be done away with ; and whenever there are found on the body of an infant marks of violence sufficient to account for its death, which marks of violence could not be pro- duced in the natural progress of the labour, or by any accident occurring afterwards, let the female be punished as guilty of murder. Medical evidence would thus be restricted to the question of the true cause of the injuries found on the child. There would be no injustice in such an enactment, for the same injuries which would destroy the life of a child that had already breathed, would effec- tually cut off all chance of the preservation of a child in whom the act of respiration had not yet taken place ; and it is in the highest degree improbable that a female would inflict such injuries on a child that did not show some signs of life. On the other hand, as, in the absence of all external injury, it is impossible to prove that a child has been murdered ; and yet it may be easy to show that the female has been guilty of criminal neg- ligence ; let that criminal negligence be punished according to its degree. The law, as it now stands, contemplates only one degree of criminal negligence, viz., the concealment of the birth ; and the concealment of the birth, except in as far as the life and well-being of the child are thereby affected, is but the concealment of shame. The concealment of the birth is criminal, inasmuch as such con- cealment presupposes the want of that assistance which all women know to be necessary to the well-being of the new-born child. Let the concealment of the birth, then, be punished as now, by imprisonment for such a time as the law sees fit. Another omission, — that of providing proper clothing and shelter for the child — at present escapes punishment altogether, and certainly demands a separate enactment. 114 LEGITIMACY. LEGITIMACY. The law always supposes that a child born in wedlock has the mother's husband for its father ; but this presumption may be rebutted by evidence of non-access on the part of the husband, or impotence, or any other cause which makes it impossible that the reputed should be the real father. There are several circumstances out of which the question of leo-itimacy may spring. A woman may bear a child after her husband has been absent from her more than nine calendar months ; nnd in this case the question arises. Does the period of utero -gestation admit of being extended beyond this the usitatum tempus pariendii On the other hand, a woman within an unusually short period of her marriage may bring forth a child capable of being reared, and here the question may arise, what is the earliest period at which a viable child may be born. Again, a woman before the expiration of the full terra of nine calendar months from the date of her marriage, say in the 7th or 8th month, may be delivered of a child having the size and general appearance of one at full term ; and it may become a question whether a child of such a size, and apparently so mature, could have been of the supposed age. Here an accurate knowledge of the growth and development of the foetus will be necessary. Lastly, a woman may give birth to a child during the life-time, or after the death, of her husband, he having been at the time of the conception of the child in such a state of feebleness or disease, or imperfect convalescence from some severe malady, as to give rise to the question whether he could have been the father of the child. A question of paternity may also arise, where there is no doubt of the legitimacy of the child, in consequence of the marriage of the mother to a second husband immediately after the death of the first. Some cases of disputed legitimacy turn on the alleged impotence of the husband. (See the Chapter on Impotence.) The questions which fall to be examined in this place are chiefly — 1. The Duration of Preg- nancy, and 2. The Viability of Children. 1. DURATION OF PREGNANCY. This is a question to be decided by medical evidence ; for, though the practice of our courts of law is to consider forty weeks as the more usual time, medical men are allowed to give evidence as to the possibility of that period being extended. The general belief among medical men, as well as among the vulgar, is, that the period of utero-gestation in the human subject is 9 calendar months, 10 lunar months, 40 weeks, or 280 days ; and we often meet v,rith the less definite expression " 9 months, or 40 weeks." Now, it is important to understand that there is a material difference between 9 calendar months on the one hand, and 10 lunar months, 40 weeks, DURATION OP PREGNANCY. 115 or 280 days, on the other ; for nine calendar months may consist either of 273, 274, 275, or 276 days, falling short of 280 by from 4 to 7 days. This want of precision in estimating the duration of pregnancy arises in part from the inadequacy of the means we possess of deter- mining the duration of pregnancy in particular cases. These means are four in number. 1. Peculiar Sensations at or about the time of conception. 2. Ces- sation of the Catamenia. 3. The Period of Quickening : and 4. A single Coitus. 1. Peculiar Sensations felt at, or soon after, Conception. — This mode of reckoning is inaccurate, inasmuch as these sensations are not defined so as to be recognized by those who conceive for the first time; they are not constant in their occurrence in the same female ; and they do not take place at any particular period. 2. The Cessation of the Catamenia. — There are also great objections to this mode of reckoning, for the catamenia may cease from causes other than conception. Hence the following case is a possible one : a woman, from some cause quite independent of conception, ceases to menstruate, and immediately before or after the next suppressed period she conceives, but she dates the conception from the first suppressed period. As the cases of protracted gestation are not very numerous, a part of them may perhaps be explained in this way. On the other hand, a female may menstruate once, or more than once, after conception, in which cases her reckoning will fall short of the real duration of pregnancy. But, eyen allowing the cessation of the catamenia to be a sound starting-point, it can give only an approximative result; for as in most women 28 days (according to the best authorities) intervene be- tween the commencement of one menstrual period and the commence- ment of another, there may be an interval between the termination of one menstrual period and the beginning of the next of nearly 28 days; say 25 days. If conception be assumed to take place on the first day after the cessation of thti. menstrual discharge, and we reckon from the first suppressed period, the calculated duration of pregnancy would fall short of the real duration by 25 days. If, on the other hand, we assume conception to take place on the day preceding the suppression, and we calculate from the last appearance of the menses, the calcu- lated duration of pregnancy would exceed the real duration by the same period of 25 days. To avoid this possible error of 25 days, accoucheurs have adopted the expedient of dividing the interval between the two periods into two parts, and reckoning from the division. In this way the possible error is reduced to twelve or thirteen days. Our estimates would differ less widely from the truth in those cases in which the interval is greatly contracted, either by the menses continuing for several days or recurring more frequently than usual, 116 LEGITIMACY. as every three weeks, or every fortnight : they would, on the other hand, be more remote from the truth in those instances in which the interval is prolonged to five or six weeks, or even two months. 3. The Period of Quickening. — The inadequacy of this event as a starting-point from which to reckon the duration of pregnancy will be inferred from what has been already stated in speaking of the signs of Pregnancy, viz. that quickening, where it is perceived, occurs at very variable periods, having a range, according to the best authorities, of six weeks (from the 12th to the 18th), and, if we combine the state- ments of several authors, of sixteen weeks, namely, from the 10th to the 26th week. 4. A single Coitus. — This is the only accurate mode of reckoning ; and a sufficient number of well-attested facts of this class have now been collected to prove that the duration of pregnancy is subject to considerable variation, as well as to a marked excess above 280 days. The following table embodies the results of 14 cases in which the duration of pregnancy was determined by a single coitus. Aveiage of the 14 cases . . . 284 days. Minimum . . ♦^ . . . 270 „ Maximum . . ... 293 „ Range 23 „ Excess above 280 days . , . . 13 „ Excess above 9 calendar months . 17 to 20 „ The inferences to be drawn from cases in which the duration of pregnancy was fixed by a single coitus, admit of being strengthened by cases of an analogous kind, in which the sudden death of a husband, or the date of his separation from his wife, is used to determine not the exact duration of pregnancy, but its minimum duration, for in using this mode of reckoning it is commonly assumed that the pregnancy dated from the very day of death or departure. The following table gives the results of 27 cases in which the exact duration of pregnancy, or the mininum duration, was determined either by a single coitus, or by the sudden death of the husband, or by his separation from his wife.* Average of the 27 cases . 284 days Minimum . . 260 „ Maximum . . 308 „ Range . 48 „ Excess above 280 days . . 28 „ Excess above 9 calendar months 32 to 35 „ The results of these cases, then, furnish the strongest possible reason for regarding the period of utero-gestation as variable and not fixed, * The author is indebted for the case of 308 days to Mr. Hewitt, a former pupil of King's College. The duration was ascertained by the sudden death of the husband. Cases of less than 260 days are excluded. DURATION OF PREGNANCY IN ANIMALS. 117 and as so great an amount of variation is shown to exist in so small a number of cases, we may fairly expect a still greater difference from the collection of a greater number of similar facts. The inference drawn from these facts derives the strongest conlirma- tion from the analogy of animals. Formerly the period of gestation in animals, like that in the human species, was held to be a fixed period. For instance, the duration of pregnancy in the mare was fixed at 11 months, and in the cow at 9 calendar months. Subsequent observations have shown that, in those animals, the period is far from being a fixed one, and has thus fur- nished a strong argument to the advocates of a variable period in the human species. The well-known observations of M. Tessier, which extended to 102 mares and 160 cows, give the following striking results: — In the Mare. In the Cow Shortest period . , . 311 days. 241 days. Longest period . . . 394 J) 308 j» Range , . 83 „ 67 „ Excess above the stated period 57 or 60 ?> 32 or 35 ,, Average period . 11 mths. 10 „ 9mtl IS. 10 3' The difference observed in the case of both these animals is very remarkable, and certainly much greater than might have been antici- pated. The excess above the assumed period is also very great in both instances. Earl Spencer has made a still more extensive series of observations on the period of gestation in the cow.* His lordship's observations were made on 764 cows, and the results may be briefly stated thus : — Shortest pei'iod of gestation, a live calf I ^^. , being produced j ^^' Shortest period of gestation, when the calf ^ ^ ,^ was reared / " Longest period of gestation . . . 313 „ Range (greatest) , . . . . 93 „ Range in the case of a viable calf . . 71 ,, Excess beyond 260 days, before which period t his lordship considers a calf decidedly > 53 „ immature ) Excess above 9 calendar months . 37 or 40 „ Excess above 10 lunar months . . 33 „ Average duration . . , 284 or 285 „ It appears also to be well made out, from his lordship's observations, that by far the majority of instances of gestation protracted beyond * See the 'British and Foreign Medical Review' for Jan. 1841. 118 LEGITIMACY. the average period, occurred in the case of bull-calves, the numbers being, of cow-calves 90, of bull-calves, 152. These observations of Lord Spencer, added to those of M. Tessier, establish beyond a doubt the fact, that the period of utero-gostation in the cow and horse, which, like that of the human subject, was for- merly regarded as fixed, is not only variable, but that the extremes are widely separated from each other, and the longest period in excess by considerably more than a calendar month of the average duration. The case in favour of a vaiiable period in the human subject admits of being strengthened by other arguments. All the functions of the human body which have been carefully examined, such as the pulse, the respiration, the secretion of urine, and the cutting of the teeth, are found not only to be variable, but to vary within wide limits. So also with those functions which have a close connection with pregnancy : for instance, the catamenia. They make their first appearance at any age, from 9 years up to 23 or 24- (and even earlier and later than those ages), and they continue up to any age from 35 to 55, or even later. In some women they recur at intervals of a month, in others of six weeks, in others of a fortnight, and each period may comprise a variable number of days. Then, again, the period of quickening varies from the 10th or 12th to the 18th or 20th week, or even later; and child-bearing, which in the majority of cases ceases at 45, may occur as late as 54, and possibly at a still more advanced age. Another argument of no slight force in favour of a variable period, and of the possible extension of pregnancy beyond the usually assigned limit, is to be found in the fact that the advocates of a fixed period are by no means agreed among themselves as to what that fixed period is to be. Thus of the seventeen medical men examined in the Gardner Peerage case, five advocated a fixed period, and were opposed to the idea of protracted gestation, but all of them stated the duration of pregnancy differently, and, with the exception of Sir Charles Clarke, who fixed it at 40 weeks or 280 days, were forced to admit a greater or less deviation from an absolutely fixed period. Dr. Gooch, for instance, stated it at from a day or two before to a day or two after 9 calendar months, and Dr, Davis at a day or two under 9 calendar months ; while Dr. Blegborough allowed an interval of from 39 to 40 weeks; and Mr. Pennington of from 37 to 40 weeks. If the advocates of a fixed period, all of them men of acknowledged eminence and experience, could differ thus widely in their estimates, they might differ as widely from nature herself. Bnt while five of the seventeen medical men examined in the Gardner Peerage case thus supported the opinion that the period of gestation was fixed, or nearly so, twelve believed that it might be protracted to 9^, 10, or 11 calendar months, or (288—290) (304—306) (334—337) days. THE GARDNER PEERAGE CASE. 119 The balance of authority, both ancient and modern, may be also adduced in support of the theory of a variable period and of possible extension of pregnancy beyond the usual period of about 280 days. Among modern authors of note may be citwl the names of Hunter, P'odere, Gardien, Velpeau, Capuron, Desormeaux, Richerand, Dewees, Hamilton, Burns, Denman, and Montgomery.* To the foregoing arguments may be added the fiict, that legal decisions in this country have been favourable to protracted gestation, and that the same may be said of the decisions and even of the laws of other countries. Thus, the law of France does not allow the legitimacy of a child born after a gestation of 300 days to be disputed, and admits evidence as to more lengthened gestation. The arguments in favour of a variable period and the possible pro- traction of gestation, then, are 1. The strong analogy of animals, whose period of gestation, like that of the human female, was originally supposed to be fixed, but which is now proved, by careful and extensive observation, to be subject to great variety, and to be much protracted beyond the assumed limit, 2. The analogy of other functions of the human body, and especially of menstruation and child-bearing, all of which present wide limits of variation in time and degree. 3. The absence of any exact conformity in the statements of those who advocate a fixed period, and deny the possibility of its extension. 4. The balance of authority, both ancient and modern, in favour of its possible extension. 5. The legal decisions and laws of our own and other countries. 6. (and this is the most conclusive). The facts founded on accurate observation in cases of a single coitus, or of sudden death, or separa- tion. These arguments must be admitted to have far greater weight than the general impression in favour of a fixed period. But, though they render it in the highest degree probable that the period of utero-ges- tation may fall shoit of, and extend beyond, 280 days, the degree to which it may be lengthened out must still remain a subject of dis- cussion; This question, of the extent to which the period of utero-gestation may be protracted, assumed a definite shape in the celebrated Gardner Peerage Case, of which the following is a brief outline. In the month of March 1796, Alan Hide Gardner, afterwards Lord Gardner, then a captain in the navy, was married to Miss Adderley. They cohabited together as man and wife from the time of their mar- riage until the month of January J 802 (except during the occasional * For the precise statements of these authorities, see the article Succession, by Dr. Montgomery, himself a firm believer in protracted gestation, in the •Cyclopaedia of Practical Medicine ;' and for the opinions of older authorities, see Beck's ' Medical Jurisprudence,' article Legitimacy. 120 LEGITIMACY. absence of the husband). On or about the 30th of January, Alan Hide Gardner took leave of his wife, and sailed a few days afterwards for the West Indies, and did not return to England until the 10th day of July in the same year, his wife remaining in England during the whole of that period. Towards the end of the year 1801, when Alan Hide Gardner was absent on his Majesty's service, his wife entered into an adulterous conversation with Henry Jadis, Esq., which Alan Hide Gardner did not discover until the month of June 1803; after which time he did not live or cohabit or have any intercourse whatever with his said wife. On the 8th of December, 1802, she was, without the knowledge of Alan Hide Gardner, delivered of a male child, which was afterwards baptized by the name of Henry Fen ton Gardner. In Easter Term, 1804, Alan Hide Gardner brought his action in the Court of King's Bench against Henry Jadis, for criminal intercourse with Maria Elizabeth Gardner, and in that action obtained a verdict against Henry Jadis for 1000^. damages. He also obtained a sentence of divorce in the Conssistory Court, and the marriage was subsequently dissolved by Act of Parliament. Alan Gardner, Baron Gardner, died on the 30th of December, 1808, leaving Alan Hide Gardner his eldest son and heir, who thereupon succeeded to the barony, and became the second Baron Gardner. On the 10th of April, 1809, Alan Hide, Lord Gardner, was married to the Honourable Charlotte Smith, daughter of the Right Honourable Robert Lord Carrington, and by her had issue Alan Legge Gardner, his only son, who was born on the 29th of January, 1810, and one daughter. Alan Hide Lord Gardner died on the 22nd of December, 1815, leaving Alan Legge Gardner his only surviving son, who succeeded to the title. Henry Fenton Gardner attained the age of twenty-one years in the month of December, 1823. Alan Legge Gardner, being an infant of the age of fourteen years or thereabouts, petitioned his Majesty for a recognition of his right to the title by letters patent, or by ordering his name to be entered on the Parliament Roll as a minor peer.* It was proved on the trial that there was a possibility of access on the 30th of January, from that date to the 7th of February, and on or after the 11th of July. Hence the three questions proposed to the medical witnesses : — 1. Could a child born on the 8th of December have been the result of sexual intercourse either on the 30th of January, or anterior to it, being 311 days? 2. Could a child born on the 8th of December have been the result of sexual intercourse on the 7th of February, or anterior to it, being 304 days ? 3. Could a child born on the 8th of December, and living to man- hood, have been the result of sexual intercourse on or after the 11th * This account is taken, with alterations, from Le Marchant's history of the case. CASE OF THE REV. FERGUS JARDINE. 121 of July, a period of 150 days, or two or three days short of five calendar months ? The first two of these questions may be reduced to one, and we shall have the following alternative : — if the child were legitimate, he must have been either a five months' child, or, to speak more correctly, a 150 days* child, or a 304 or 311 days' child (one calendar month and two or nine days beyond the usitatum tempus pariendi). The latter alternative, viz., gestation protracted to the 304 or 311 days, was the one chiefly insisted upon in this celebrated trial. Of the medical witnesses who were examined, the majority gave their evidence in favour of protracted gestation ; a small number of influential names was ranged on the side of a fixed period. As the opinions of these latter authors have been already stated, and the sub- ject of protracted gestation has been discussed at as great length as is consistent with the limits of this work, the reader is referred for fur- ther particulars to Dr. Lyall's pamphlet.* The decision of the case did not turn upon the medical evidence, but upon the adultery of the mother of Henry Fenton Jadis. The claim of the petitioner, Alan Legge Gardner, was allowed. 2. VIABILITY OF CHILDREN. The question, What is the shortest period of gestation at which a viable child may be born ? was raised in the Jardine case, which, though less known than the Gardner Peerage case, is equally interest- ing, as no less than 14 medical men, and a still greater number of non-professional witnesses gave their evidence. In this case, too, there was great difference of opinion among the medical witnesses. The evidence of Drs. Alison and Christison was admitted, simply because as Lecturers on Forensic Medicine, their attention had been directed to the question involved ; and it may be safely affirmed, that the evidence of the last-named witness. Dr. Christison, threw more light upon the case than 1;hat of all the other witnesses put together. The following is a short abstract of this case : — The defendant was married on the 3rd of March, 1835 ; and on the 24th of August following, his wife was delivered of a girl. Supposing this child to have been the ffuit of sexual intercourse on the day of the marriage, it was only 174 days, or five calendar months and twenty- one days old. The infant, which was undoubtedly immature, though the degree of immaturity could not be ascertained or determined, died on the 20th of March, 1836, having survived, as nearly as possible, seven months. The libel charged the defendant with having committed fornication * ' Medical Evidence relative to the Duration of Human Pregnancy, as given on the Gardner Peerage Case.' 122 LEGITIMACY. with his wife before mairiage. A great many witnesses were called, some to estiiblish the possibility of sexual intercourse before marriage others to show that the child, though small and feeble, was not immature, or at least not so immature as the date of the marriage, would make it ; and others to speak to the impossibility or improba- bility of a child surviving at that early period. The extent to which the allegations of the libel were made good, and the vague nature of the evidence adtluced in their support, will be best seen by the follow- ing extract from the decision of the Presbytery, November 7, 1838: " That the testimony of the several witnesses, both with respect to matters of fact, viz., the appearance of the child at birth, &c., and also with respect to the opinions of medical men regarding the viability of such a premature child as the child in question is said to be, is of such an opposite and contradictory nature, that the Presbytery, with their present light, have great difficulty in coming to any decision on these points. The Presbytery, therefore, agreeably to a common maxim of law, Satius est impunitum reliiiqui f acinus nocentis quam innocentem damnan, find the libel not proven." * The principal points established by the general and medical evidence in relatiou to Mrs. Jardine and her infant were, that she had men- struated as usual the week previous to her marriage; that she was, both before and after her marriage, in a very weak state of health ; that she was herself a seven months' child ; that she had a second child, a daughter, which she believed to have been born "just about the commencement of the eighth month of her pi'egnancy," and that she had not provided baby-linen for this child. As regards the infant, the evidence, though contradictory on many points, showed that it was small (it weighed three pounds when born), very feeble, and decidedly immature, though no data were adduced to show the degree of the immaturity. It required to be nursed with care, but none of those precautions for preserving the child's warmth, such as wrapping it in wool, causing an adult female constantly to sleep with it, or to keep it in her arms, were taken, which seem to have been absolutely necessary in the cases of Drs. Rodman and Outrepont, presently to be described. The special question raised in the Jardine case was this — Could a child born 174 days, or five calendar months and twenty-one days after marriage, be reared to the age of seven months ? and the more general question which the case suggests is — What is"^the earliest period of gestation at which a viable child may be born ? or, in other words, what is the earliest period of gestation at which a child has been born, and has survived its birth so long as to prove that there was no physical obstacle to its attaining the adult age? * ' Record of the Proceedings in the reference by the Synod of Fife, to the Venerable the Greneral Assembly of the Church of Scotland, in May, 1839, of the Case of Mr. Thomas Barclay, Town Clerk, and Nine of the Parishioners of Kinghorn, against the Reverend Fergus Jardine.' Edinburgh, 1839. QUESTION OF EARLY VIABILITY. 123 Now it is universally admitted that a child may he born and reared to manhood at the seventh and eighth, as well as at the ninth month. All authorities are agreed as to the possibility of a child of seven calendar months living to manhood ; it is only, therefore, with regard to periods anterior to this that any doubt exists. On the other hand, in spite of the case of Fortunio Liceti, said to be born at four and a half months, and to have lived to 80, we may pretty safely affirm that a viable child cannot be born before five calendar months, or 150 days. Our attention, then, will have to be directed to the periods of five and six months, and it may be useful, in this place, to give a short tabular summary of the leading particulars of the cases which are best attested, and most worthy of confidence. In the cases of Outrepont and Belloc, the age stated is that at which the children were last seen alive by the reporters. Table showing the Lengths and Weights of Children reported to have been born during the 5th and 6th Months of Gestation, with the assumed Age and the probable Age, according to the Estimates and Observations given at pages 66, 67. Author. Length. Weight. Survived its Birth. lb. oz. 1 13 1 yr. 9 m. U 0 8 years. •• 17 years. U 0 2 days. 2 0 Ai days. 1 5 8 days. 1 1 Si hours. 1 8i 3i hours. Asserted Age. Age according to Estimates and Observations, Rodman Outrepont Belloc . Bucholtz* Koppf . Fleischmann + Christison J Mr. Thomson I Inches. 13 at 3 weeks. 13* 121 14 12i lU 13 I2i Days. 133 175 or 189 6 months. 189 days. 182 168 167 5 months. Possibly 5 months. 6 months. Possibly 5 months. 6 months. 6 months. Possibly 5 months. Possibly 5 months. 5 months. This table is certainly confirmatory of the views of the reporters of the several cases : there is not one of the cases in which the asserted age does not correspond pretty closely with the estimates and measures * Beitrage, ii. 104. f Jahrbuch, iii. 128. J Henke's ' Zeitschrift,' vi. $ Evidence in the Jardine case. II Of Alva, Stirlingshire, quoted by Beck, p. 212. . 124 LEGITIMACY. already given, and, in some cases, the observed weights and measures might have belonged to an earlier period of gestation. if now we revert to the Jardine case, we find a weight of 3 lbs. stated to belong to a child born at 174 days, or before the completion of the 6th month, which weight is a pound in excess of any of the weights given in the table. It also exceeds the weights given at p. GG, with the exception of the very doubtful instance of 3 lbs. 13 oz. Though the lengths and weights contained in the above table afford a strong probability that the estimated periods of gestation in some, at least, of the cases is the true one, that probability requires to be con- firmed, by contrasting the other particulars of their histories with the acknowledged signs of immaturity. The following are the signs of maturity and immaturity, according to Fodere and Capuron. The signs of maturity are the following : The ability to cry as soon as the child reaches the atmospheric air, or shortly thereafter, and also to move its limbs with facility and more or less strength ; the body being of a clear red colour ; the mouth, nostrils, eyelids, and ears perfectly open ; the bones of the cranium possessing some solidity, and the fontanelles not far apart ; the hair, eyebrows, and nails perfectly developed ; the free discharge of the urine and meconium, a few hours after birth ; and, finally, the power of swallowing and digesting, indicated by its seizing the nipple, or a finger placed in its mouth. The signs of immaturity, on the other hand, are the following: The length and volume of the infant much less than those of an infant at full term ; it does not move its members, and makes only feeble motions ; it seems unable to suck, and has to be fed artifi- cially; its skin is of an intense red colour, and traversed by numerous bluish vessels ; the head is covered with a down, and the nails are not formed ; the bones of the head are soft, and the fontanelles widely separated ; the eyelids, mouth, and nostrils closed ; it sleeps continually, and must be preserved by artificial heat ; and, lastly, it discharges its urine and meconium imperfectly, and often after a long interval. The presence of the membrana pupillaris, the high position of the centre of the body, the non-descent of the testicles, the large size of the head as compared with the body, the great prominence and deep red colour of the parts of generation, and the absence or scanty deposit of sebaceous matter on the skin, may be mentioned as additional signs of immaturity. By comparing this description with some of the more remarkable recorded cases, it will be seen what degiee of probability attaches to the estimates of authors. Only two of these cases are here selected for consideration, viz., those related by Dr. Rodman of Paisley, and Dr. Outrepont. Dr. Rodman's case is as follows : DR. Rodman's case. 125 After describing the mother as " more cautious in her decisions, accurate in her observations, and steady in her deportment, than what is usually met with in society," and stating that she had borne five children, and " was confident that the period of her gestation was less than nineteen weeks," Dr. Rodman says, that premature labour came on in consequence of fatiguing exertions, and she was delivered of a living male infant. " Not daring to allow the washing of the infant's body, he was speedily wiped and wrapped in flannel, with only an opening in the dress around his mouth for the admission of air ; and by the time the dressing was over, the mother was ready to take him into the warm bed with herself. It is common, if there be much apparent weak- ness, to feed a child the first twelve hours after birth very frequently, yet, in this instance, although the child was weak, no feeding was attempted till beyond that time ; the nourishing heat with the mother in bed was relied on. On ihe following day, the head, body, and extremities of the child were surrounded with fine cotton-wool, pressed to appear like cloth, to the thickness of two or three folds, and over that the flannel as before ; and again the child was given to the mother in bed. His vital energy was so deficient, that even with this dress, of himself he was unable to support the degree of warmth which was necessary to his existence. The heat of a fire was evi- dently injurious, as he soon became weaker when exposed to it, whilst the warmth of the mother in bed enlivened and strengthened him. Too much heat induced a sickly paleness of his face, with an obvious expression of uneasiness in his countenance ; and the abstrac- tion of heat, even by tardily undressing his head, brought on a nervous affection, or starting of the muscles all over his body. From seeing how these morbid affections were induced, the child was kej)t regularly and comfortably warm, by the mother and two other females alternately lying in bed with him for more than two mouths. After this he could be left alone from time to time, but was still undressed very cautiously and only partially at any one time. It was not till the child was three weeks old that the length, or weight of the body could be ascertained. The length was found to be 13 inches, the weight 1 lb. 13 oz. avoirdupois. It was extremely difficult to get the child to swallow nourishment the first week ; the yellow gum soon came on, and the thrush seized him severely on the eighth day, and was not cured till the end of the third week. During the first week he was fed with toasted loaf bread boiled with water, sweetened and strained through fine linen ; in the second week twenty drops of beef-tea were added to the two or three teaspoonfuls which he took of this nourish- ment, and small doses of castor-oil were administered. At the end of three weeks he began to swallow teaspoonfuls of his mother's milk, and in two days afterwards he made exertions to suck. His mother's milk was gradually substituted, at least in part for the panada, though this was still continued occasionally with a few drops of port wine. 126 LEGirraACY. Under this careful management he attained the age of four months, at which time his health and excretory functions were peculiarly regular." Five months after this, as we find from a second paper by Dr. Rodman,* this little child was still doing well. In this paper he confirms what he had stated in the first : he describes the mother as tall, robust, and healthy, and states that she had a peculiarly accurate knowledge of the time of her previous gestations, and does not hesitate still to aflfirm, that the period in this instance was rather under nineteen weeks. f Dr. James Hamilton, in his evidence given in the Jardine case, states that this infant lived a year and nine months, and consequently was a viable infant ; but that from the facts of the case, and some circum- stances communicated in a correspondence with Dr. Rodman and himself, he had always been impressed with the belief that theie was some mistake in the woman's reckoning, and that the infant was a dwarf. Dr. Hamilton adds that the infant was considerably smaller than those puny infants born within the six months, whom he had seen drag on a miserable existence for four or five days. It must be admitted at once that, in this instance, an extremely feeble and immature child was reared by very judicious treatment. It cannot be denied, too, that the estimate of the child's age, formed by the mother, was at least as likely to be correct as such estimates ever can be, and the degree of doubt which attaches to the case is only such as attaches to a mother's estimate of the age of a child. The length and weight of the child, too, are in keeping with the other lengths and weights given in the table at p. 123, and they will be found to coincide with the extreme weight and length of the tables at pp. 66, 67. The absence of any description of the appearances presented by the child prevents us from determining, with any approach to accuracy, its degree of immaturity. It might have been a' five months' child, but there is no ground for supposing it to have been born before the com- pletion of the fifth month. The case related by Dr. Outrepont, of Bamberg, is a very valuable one, for it is the only quite unequivocal instance hitherto published, of the rearing of a six months' child. The particulars are given so fully, and with such precision, that even Hencke, who previously denied the possibility of such an incident, has candidly admitted that Outrepont's case is an unequivocal example. J The evidence is as complete as it is possible to be in any case of the kind. It is complete both as derived from the date of the mother's impregnation, and as drawn from the structure and history of the child. The mother, a * 'Ed. Med. and Surg. Journal,' vol. xii. f Case of a child born between the fourth and fifth month, and brought up. By John Rodman, M.D., Paisley, 'Ed. Med. and Surg. Journal/ vol. xi. p. 445^ The facts of this case were attested by Mr. White of Paisley. X ' Zeitschrif t,' vi. 27. outrepont's case. 127 young woman, whose catamenia had always been perfectly regular, menstruated as usual ten days after her marriage, and subsequently to this time was repeatedly connected with her husband. About a fortnight after this menstruation, she underwent a general change in appearance, and began to have frequent attacks of vomit- ing and fainting, symptoms which she never had in her life before. These symptoms continuing the catamenia did not return : and about twenty weeks after their last appearance, she felt the first movements of the child. Five weeks after this, and twenty-seven weeks (twenty -five?) after the last appearance of the catamenia, she was seized with labour-pains, and uterine hsemorrhage ; upon which Dr. Outrepont having discovered that the hemorrhage proceeded from the placenta being attached over the os uteri, encouraged the labour, and brought it forthwith to a prosperous conclusion. Here the evi- dence of the child being not more than twenty-five weeks old, is as strong as in the nature of things it is reasonable to expect. The state of the child at birth is still more unequivocal. It was a boy, and breathed immediately on being born. It measured thirteen and a half inches, and weighed one pound and a half. Its skin was covered with smooth lank down, and was much wrinkled. The whole extremities were extremely small in proportion to the trunk, and were kept constantly bent over the body, as during the existence of the foetus in the womb. The nails of the fingers and toes were like mere white folds of skin, the testicles were still within the belly, and the pupillary membrane was entire. The child whined, but could not cry— slept almost constantly — awoke only once a day — seldom opened its eyelids, and was obviously insensible both to light and sound. The first excretion of urine took place on the seventh day, and the first evacuation of the bowels on the ninth. Subsequently the urine was voided once in forty-eight hours, and the faeces every two or three days. It was placed in a basket filled with wool, kept in a uniform temperature, and moved with great care. For some time it was fed with the spoon on diluted milk and sugar. In four weeks the down began to drop off from the skin. In fifteen weeks it had made very little progress in any respect. The wiinkles had disap- peared, however, from the skin, and the length was increased an inch and three quarters. But from this time, which corresponded with the fortieth or forty-second week after impregnation, — that is with the full period of utero-gestation, — it made rapid advances; sleeping less, eating more, crying strongly, and becoming evidently sensible to sound, and pleased with the light. When fourteen months old, it was of the weight and stature of a child born at full term. In the eighteenth month, the testicles descended into the scrotum, without causing him any annoyance. In like manner, the teeth began to appear early in his third year. He did not begin to walk till half a year later ; and at that time differed from other children of the same age, not only in littleness, but likewise in the singularly old 128 LEGITIMACY. expression of his countenance. When Dr. Outrepont saw him in 1816, he was eleven years of age, was as big as a boy of seven or eight, and had just begun to read and write.* The length and weight in this case are also in keeping with the lengths and weights in the table at p. 123, and are much within the extremes given in the tables at pp. 66, 67. The signs of immaturity are also so well marked and so minutely described as to be decisive of the possibility of rearing a child born at the end of the sixth solar month, or about twenty-six weeks. Having discussed at length the two great questions connected with the subject of legitimacy, it will be necessary to say only a few words on some questions of less interest and importance. The question of paternity, as has been already stated, may arise where a woman, soon after the death of her husband, marries a second time. Sometimes this question assumes the shape of the one last dis- cussed. A child is born within five months, or thereabouts, of the death of the first husband, and the question of paternity becomes one of viability. Where the child is of such an age as that it might have had either husband for its father, the question of paternity must be decided by a reference to the state of health of the deceased husband dt the presumed time of conception. Another class of questions, of little importance and rare occurrence in this country, may arise in slave-holding states, where the reputed parents of a child are of different colours, and the offspring differs in appearance from the majority of children of mixed marriages. Some discussion has taken place as to the kind and degree of evidence of live-birth which may be necessary to establish a right of inheritance under the tenure known as ' tenancy by the curtesy.' '' When a man marries a woman seised of an estate of inheritance, and has by her issue born alive, which was capable of inheriting her estate. In this case he shall, on the death of his wife, hold the lands for his life, as tenant by the curtesy of England." It appears that the meaning of the expression born alice, is not the same in this case as in cases of infanticide. It has been decided that in questions of tenancy by the curtesy, any kind of motion is evidence of live-birth. Thus, in the case of Fish v. Palmer, tried in 1806, " a twitching and tremulous motion of the lips" was held to be sufficient evidence of live-birth. The question, how far monsters are capable of inheriting, has been raised, and answered by Blackstone, who states that " a monster which hath not the shape of mankind," " hath no inheritable blood ;" but if, in spite of deformity, " it hath human shape it may be an heir." * This case is taken from Dr. Christison's evidence on the Jardine case, with alterations and additions suggested by the perusal of the case in the 'Zeitschrilt, liir die Staatsarz,' vi. 19. It may be well to state that Dr. Christison admitted the possibility of a child bom after 174 days being reared. 129 CHAPTER IV. LIFE-ASSURANCE. FEIGNED DISEASES. LIFE-ASSURANCE. The medical man performs many important functions in relation to life-assurance. With the exception of the simple facts which the actuary obtains from mortuary registers as his materials for cal- culating common average risks, almost all his information respecting special risks, and the influence of particular diseases on the duration of human life must be drawn from medical sources. Every well-conducted assurance office, moreover, employs a medical man to examine and report upon the state of health of all persons making personal application to the office, and, in other cases, intrusts the duty to some medical man chosen for the purpose. The ordinary medical attendant of the applicant is also consulted respecting his state of health and the diseases from which he may have sxiffered. The services of the medical man are still more indispensable in the case of those offices which undertake the insurance of unsound lives. He is also employed by benefit societies to ascertain the state of health of persons applying for admission into them. Similar services to these have also to be occasionally performed in examining emigrants and recruits. The insurance offices generally provide the medical examiner with a printed list of questions, prepared under medical advice, or suggested by their own experience, relating to the state of health of the applicant, his family and personal history, his occupation and habits, the diseases which he has suffered, and such other particulars as are presumed to afi^ect the probable duration of his life. Similar questions are drawn up for the guidance of the medical referee. From this brief statement it will be seen that the duty of the medical examiner resolves itself into a work of inquiry and a work of personal inspection and examination, respecting both of which a few practical suggestions may be offered with advantage. The inquiries which the medical examiner is expected to make relate partly to the family history and partly to the personal history of the applicant. The importance of the first class of inquiries rests upon the ascertained prevalence of hereditary predisposition whether of a favour- able or unfavourable character. As a general rule, the children of those who have died at an advanced age themselves live to be old, while, on the contrary, the children of parents who have died young are likely to be short lived. Moreover, a considerable number of dis- eases which sensibly affect the duration of human life are transmitted * K 130 LIFE-ASSURANCE. from parent to oflsi)ring, or, passing over one generation, fi-om grand- sire to grandson. The medical examiner should, therefore, begin by ascei-taining whether the parents of the applicant are living or dead ; and, if living, what age they have attained, if dead, at what age they died. This inquiry should be extendefl to the brothers and sisters, and in some instances to the uncles and aunts of the applicant. As a general rule it will not be necessary to extend the inquiry beyond the father and mother and the brothers and sisters of the applicant, if the answers respecting them prove favourable ; but if these near relations have died early, or if they appear to be subject to some hereditary malady seriously affecting the duration of life, it may be necessary to include in the inquiiy a larger circle of relationship. Having ascer- tained the ages of the living and deceased members of the applicant's family, the medical examiner should next inquire into the causes of death in the case of those deceased members of the family who have not died of old age. If one or more should be found to have died of pulmonary consumption, asthma, insanity, gout, or disease of the heart ; or of apoplexy or dropsy at an early age ; the fact would have to be noted as more or less seriously affecting the value of the life under examination ; and similar importance would attach to the ascertained prevalence of any of these diseases among the living members of the applicant's family. From the family history of the applicant the examiner would pass to his personal history, which would comprise his age, his social relation (whether mamed or single), his occupation, place of residence, and habits of life, and the diseases to which he has been subject, not for- getting to ascertain whether he has had small-pox, or been vaccinated. Among the diseases or symptoms of disease to which the gi-eatest im- portance attaches may be mentioned spitting of blood (as affording a strong probability of consumption) ; gout, acute rheumatism, and asthma (as both liable to recur and as laying a foundation for serious organic changes) ; dropsy (as a common result and indication of severe organic mischief); inffammation of the lungs (as leaving behind it some unfavourable change in those organs, or as being the direct consequence of tubercular deposit) ; fits (as betraying serious lesion of the nei-vous system); rupture (as involving danger of strangula- tion) ; and calculous disorder (as obviously tending to shorten life). The personal examination will have to be conducted with gi-eater or less care and minuteness as the family and personal history have proved favourable or otherwise. A favourable personal and family history will justify a cursory inspection and examination. If the person is well formed ; the complexion healthy ; the pulse regular and equal, of fair force, and not exceeding 70 or 75, or falling much below 60 (in the female not more than 80) ; and if the breathing is free and tranquil, further inquiry will be unnecessary. If, on the contraiy, the family or personal history is unsatisfactory; if the person is ill formed or disproportioned, if the pulse is ii-equent or EFFECT OF LOCALITY AND CLIMATE. 131 otherwise abnormal, and the respiration unnatural, and especially if the applicant has been attacked by any serious disease, a more minute examination directed to the condition of the nervous system, of the lungs, or of the heart, will be required. In the examination of the chest, percussion and auscultation should be employed, and in exa- mining the lungs the spirometer of Dr. Hutchinson may be used with advantage.* To these general observations on the duties of the medical examiner such short statements as are consistent with the narrow limits of this work respecting the influence on longevity of place of residence, change of climate, occupation, and habits of life, of peculiarity of constitution, of hereditary predispositions, and of pre-existing disease, may be added with advantage. Place of Residence. — The principal facts which have been ascer- tained respecting the place of residence of persons living within the limits of their native country are the following : — That the inhabitants of the rural districts are longer lived than the inhabitants of towns. 2. That large cities are more fatal to life than small ones. 3. That marshes, and the low-lying districts on the banks of rivers, are less healthy than more elevated spots. 4. That of two districts of equal elevation that which has a sandy or gravelly soil is healthier than that which consists of clay or rich alluvium. 5. That close, damp, and ill-drained houses are peculiarly fatal to life. Such considera- tions as these ought, in extreme cases, to influence the medical examiner in selecting lives for assurance. It is obvious that the inhabitant of Glasgow or Liverpool has not so good an expectation of life as the inhabitant of London, and a much worse expectation than a resident in the country ; that a residence in London on the south side of the Thames entails greater risks than a residence on the north side ;t and that the tenant of a close, damp house is not so good a life for assurance as a man who occupies a spacious, dry, and well-built residence. Change of Climate. — The removal from a temperate or a cold climate to a hot one, or the reverse, affects the duration of life much more seriously than any change of residence from one part of a man's native country to another. Our insurance offices, accordingly, either lefuse to insure lives at all in extreme cases, or demand additions to the usual rate of premium, varying with the ascertained or esti- mated increase of risk. The most precise information Vhich we possess in reference to this subject is drawn from the reports of the mortality of our troops and seamen employed in different parts of the world ; from which it appears that while the difference between low * For a description of this instrument, with directions for Its use, tables of reference, and the indications which it affords, the reader may be referred to Hoopers ' Physician's Vade Mecum,' 5th edition, p. 162. t The deaths in London per million inhabitants, on an average of fifteen years, have been as follows :— West districts, 3,676 ; Central Districts, 4,402 ; Xorth districts, 4,670; East districts, 5,435 ; South districts, 6,535. 132 Line- ASSURANCE. and damp situations and dry and elevated ones prevails in every part of the world, the risk to life increases with the temperature, attaining its maximum within the tropics, and falling to the standard of Eng- land, or even below it, in cold or temperate regions. Some assurance offices, acting upon this general principle, allow the assured to reside without extra charge in any part of the woild lying beyond thirty degrees from the equator, requiring from those who take up their abode within these limits an extra payment roughly proportioned to the additional risk. Occupation. — The occupations which have been pioved to affect injuriously the duration of human life are those which lead to ex- cessive indulgence in spirituous liquors, those which combine sedentary habits, or a minimum of exertion, with exposure to a close and heated atmosphere, those which entail undue exposure to the weather with hardships and privations, those which require long hours of work, and a sacrifice of natural rest, those which are carried on in clouds of dust, and those which bring men in constant contact with poisonous sub- stances. The employments which demand special mention, as belong- ing to these several heads, are licensed victuallers, potboys, and brewers' draymen ; compositors, tailors, and drapers' assistants ; soldiers and sailors during active warfare; bakers; knife and needle grinders; house-painters, manufacturers of cards enamelled with lead, and men who work with mercury, phosphorus, or the salts of arsenic. One occupation not easily brought under any of these heads has been shown to shorten life without causing an undue amount of sickness, namely, the employment of the butcher. The most important of the above employments, in its bearing on life-assurance, is that of the licensed victualler, whose life is very generally looked upon with suspicion, and even deemed uninsurable in the absence of very distinct proof of temperate habits. Habits of Life. — Luxury, sloth, dissipation, and intemperance, are all of them very fatal to human life ; but the last is the only one of which it is easy to obtain distinct proof. When the fact of intempe- rance is clearly established it aflbi ds groi'.nd for fhe peremptory rejec- tion of the life. It is also well ascertained that unusual risk attends the assurance of the lives of persons living in a continual state of pecu- niary difficulty and embarrassment. Peculiarity of Constitution. — Under this head it will suffice to notice the scrofulous constitution ; the long neck and narrow chest so common in consumptive patients; and the short neck, florid complexion, large chest, and tendency to corpulency of the victims of apoplexy. Hereditary Predisposition. — 'The most important of hereditary pre- dispositions in relation to life-assurance is pulmouaiy consumption, a disease which destroys one in seven of the entire English population, and more than one in four of the adult population of the metropolis, being peculiarly fatal to men following sedentaiy occupations, and to persons of dissipated and intemperate habits. The inquiries of the PEE-EXISTING DISEASE. 133 medical examiner should be especially directed to discover traces of this disease in the family history, and great importance should be attached to the occurrence of several deaths from this cause among the nearest relatives. Insanity, gout, asthma, urinary calculus, disease of the heart, dropsy, and apoplexy, especially when they appear to have caused the death of more than one member of the family at a comparatively .early age, are also deserving of the serious attention of the examiner. Pre-existing Disease. — The medical examiner will have to form his own estimate of the influence which previous attacks of disease may have had upon the health of the applicant and the value of his life. As a general rule, it may be stated that the febrile exanthemata which make their attacks chiefly in childhood, and the typhus or typhoid fever of the adult, do not permanently affect the value of life. Attacks of erysipelas must be viewed differently, as this is a disease very apt to recur. The same remark applies to attacks of gout, acute iheu- matism, and asthma, and in a very peculiar manner to attacks of pul- monary consumption, a disease which often proves fatal after several distinct attacks. The importance of the symptom of spitting of blood, as affording a probability of a previous attack of consumption, has been already insisted upon. But the medical examiner ought to bear in mind that vomiting of blood from the stomach may have been confounded with spitting of blood from the lungs ; and that even where there is no room to doubt that the blood was brought up by an effort of coughing, it may have come from the throat, or from some slight abrasion of the lining membrane of the windpipe. Even when the blood is shown to have come from the lungs it may have been the result of some great exertion immediately preceding it, or, in the absence of such explanation, it may have accompanied the formation of bronchial polypus, or resulted from the discharge of an aneurism into the air-passages. In this latter case, the symptom would be still more formidable than if it had resulted from tubercular disease of the lung itself. The quantity and colour of the blood alleged to have been discharged by coughing are points of the utmost importance. The expectoration of a considerable quantity of vermilion-coloured blood would always constitute a sufficient ground for the rejection of a life ; but a scanty expectoration of blood, whether light or dark coloured, should always lead to a minute and careful examination of the chest. If inflammation of the lungs, or other severe disease of those organs, or repeated attacks of bronchitis, figure in the previous history of the applicant, there would be the same reason for submitting the chest to careful examination ; for these diseases are not only im- portant in themselves, but may be the result of tubercular deposit, on the one hand, or may lay the foundation for mortal diseases of the heart on the other. Repeated attacks of bronchitis, for instance, may be expected to occasion emphysema, and to be followed by hypertrophy of the heart. 134 LIFE-ASSURANCE. If the medical examination into the applicant's family and personal history, and into his existing state of health, should prove favourable, his life would naturally be recommended for assurance on ordinary terms ; but if unfavourable, the somewhat difficult question arises whether the life should be altogether rejected or accepted on condition of a more or less considerable addition to the ordinary premium, or (what amounts to the same thing) on payment of the premium re- quired for a healthy person of a more advanced age. Such adjustments can only be safely made by a medical man of sound experience and large medical knowledge ; and it would be useless to attempt to lay down for the guidance of the examiner in this matter any rules, how- ever general. But the medical examiner may not only be required to give his advice in cases of insurance for the whole of life, he may also be required to determine the propriety of insurances on unsound lives for short periods, and to suggest the teims upon which they ought to be effected. Cases are of common occurrence in which it is of the utmost importance to effect an insurance for a short term, as of one or two years, upon a life which must be rejected if offered for the whole of life. A young person, for instance, who has already had symptoms of pulmonary consumption, and whose chest has been ascertained to be unsound, may desire to effect an insurance on his life for one year, and the medical examiner may have to report on the expediency of under- taking the risk. The considerations which would guide him in his decision are obvious. Pulmonary consumption may prove fatal in any one of a considerable series of years, and the chances against an attack of the disease falling in any particular year are considerable ; and even on the assumption of its occurring in the year covered by the assurance, there is the favourable chance of its commencing its attack at a late period of the year, and either not proving fatal in that attack, or (as the disease in its fatal attack has an average duration of nearly two years) not having a fatal issue till long after the period covered by the assurance has run out. Similar reasonings apply to other severe dis- eases, and, with little modification, to the assurance of unsound lives. On this branch of the subject, too, it is not possible to lay down any precise rules. For forming a right decision upon this class of cases large professional knowledge must be combined with sound judgment. On the purely legal bearings of the subject of life assurance little need be said. It is obvious that the contract entered into in a policy of insurance may be rendered Void by any intentional concealment or omission of such particulars of the previous health or habits of the applicant as, if known, must have caused the life to be rejected, or ac- cepted only on more onerous terms : also by omitting to name the medical men who have attended him in any serious illnesses. But even where there has been no fraudulent concealment, questions have been raised as to the tendency of particular diseases, such as indigestion, gout, or mental unsoundness, of accidental injuries, such as fractuies, and of FEIGNED DISEASES. 135 particular habits, such as smolving and opium-eating, to shorten life. On all such questions there i-; much room for difference of opinion among even well-informed medical men. The definite questions now commonly prepared for the guidance of the medical examiner, and the experience of insurance offices of the difficulty of obtaining a verdict in their favour, except in cases of undoubted fraud, tend greatly to limit the number of actions at law, and to deprive this subject of some of the legal interest which it for- merly possessed. But the importance of the subject in every other point of view, and the value of the services of the medical examiner and referee, is on the increase as the value of the assurance of life and health becomes more fully appreciated, and the practice of insurance proportionally extended. FEIGNED DISEASES. Though feigned diseases are not of very great importance in a legal point of view, and though cases of imposition rarely occupy the atten- tion of our higher courts of law, the subject is one which very pro- perly finds a place in a medico-legal treatise. Diseases and disabilities are feigned from a great variety of motives. The soldier or sailor pretends to be ill to escape from duty, or to ob- tain his discharge from the service, and the mendicant to avoid labour. Sickness is often feigned to obtain parochial relief, or to impose on private benevolence ; to defraud benefit societies ; to procure the comforts of an hospital ; to obtain compensation for some pretended injury; to procure a release from confinement, or exemption from punishment : and there are many persons, particularly young and un- married females, who, without hope of gain, feign diseases in order to excite public interest and curiosity, or private sympathy. The persons most prone to feign diseases are those who congregate most ; as soldiers, sailors, prisoners, beggars, and school boys and girls. But the best school for feigned diseases is the army, especially in countries where the conscription is in force. Thus Fodere, speaking of the time when the conscription was in full force in France, says that malingering " was brought to such perfection, as to render it as difficult to detect a feigned disease, as to cure a real one." In treating the subject of feigned diseases a classified list will first be given of the principal diseases and defects which have been feigned; and this will be followed by rules for their detection. Classified List of Feigned Diseases and Defects, It is difficult to form any classification of feigned diseases which shall be free from many objections. The most natural is into, 1. Dis- seases obvious to the senses; 2. Diseases and defects of a simple kind, not obvious to the senses, but depending upon the description of the impostor ; and, 3. Diseases of a more complicated nature. 136 FEIGNED DISEASES. 1. Diseases obvious to the Senses, This class contains the following subdivisions. a. Increased and diminished size of parts. 6. Malformations, c. Wounds, ulcers, and superficial inflammations, d. Discharges, e. Spasmodic affections. /. Paralytic affections. a. Increased and diminished Size of Farts. — Tumours. A fa- vourite mode of producing tumours is by injecting air beneath the cellular membrane — beneath the skin of the abdomen to imitate ascites, into that of the scrotum to imitate hydrocele and hernia, under the scalp to give the appearance of hydrocephalus, into various parts of the limbs, with the assistance of ligatures, to imitate local swellings. This imposition may be detected by the touch, and by uncovering the tumour and searching for the aperture through which the air has l»een introduced, which aperture is generally found covered by a small piece of plaster. Tumours are also produced by pressure. Swellings on various parts of the limbs, anasarca, varicose veins, and an appearance resembling elephantiasis, have been produced by ligatures ; and oedema of the upper extremity by hanging the limb over the back of a chair previous to the medical visits. In such cases marks of the pressure will be discovered on careful search. Tympanites has been imitated by swallowing air, or drinking large quantities of chalk and vinegar. In such cases, a solution of Glauber's salts with weak tobacco-water has proved very efficacious in the hands of Dr. O'Hara. The appear- ance of an abdominal tumour has also been produced by forcibly elevating the spine at the loins whilst lying on the back. Tumours have also been imitated by the use of substances extraneous to the body, as polypus of the nose, by means of the testes of a cock, or the kidneys of a rabbit retained in the nostril, and sometimes impregnated with foetid juices. Strong sternutatories will assist us in unmasking these cases. Hcem^rrhoids have been imitated by the bladders of rats or small fish partly introduced into the rectum ; Prolapsus ani by the gut of an ox or of a sheep, or by the everted anal extremity of the bowel of a colt or hog. In one case mentioned by Percy and Laurent, prolapsus ani was actually produced by passing into the anus the bladder of a sheep, distending it with air, and forcibly retracting it. Prolapsus uteri has been imitated by similar means ; Hydatids of the uterus by vesicles prepared from the intestines of a pig ; malignant tumours by a sponge soaked in various colouring matters ; and Hernia has been feigned by the injection of air, or by the forcible retraction of the testicles towards the rings. Cancer has been imitated by a cow's spleen, and by a sponge moistened with milk, and fixed under the armpit. Swellings of tlie Joints, intended to represent white swellings, have been produced by various acrid plants, as the ranunculus acris and ranunculus sceleratus, applied to the part. Enlargement of the abdomen in the female has been simulated by a pad. Partial Atrophy may be produced by pressure. DISEASES OBVIOUS TO THE SENSES. 137 The frauds contained under this head only require, for their detection, a careful examination of the part itself, by the eye and by the touch. b. Malformations. — Lateral curvature of the spine has been imi- tated. This simulated deformity is always in the dorso-lumbar region ; the curve always single ; the convex side not gibbous ; there are folds of skin, generally two in number, on the concave side ; and the haunch of that side is raised so as to give to the extremity the appearance of being shortened. In morbid deviations, on the contrary, the seat of curvature is variable ; there is more than one curvature ; the convex side is gibbous ; the folds of skin, if present, are very slightly marked, and there is little or no inclination of the trunk, or elevation of the haunch. Gibbosity, or elevation of the shoulders, wry neck, hip-disease, and various contractions of the limbs or joints, are imitated by obstinate and long-continued flexion of the part, aided by inaction and the use of tight bandages. Sometimes the contraction is attributed to a burn or previous injury, in which case a wound is made to bear out the assertion. More commonly these contractions are attributed to a previous attack of rheumatism. In these cases there is generally ground for suspicion when there is no cicatrix, and no atrophy of the limb, but on the contrary, tension, hai-dness, and swelling of the contracted muscles. Many means have been proposed for the detection of this class of impositions ; such as compressing by a tourniquet the nerves supplying the contracted muscles ; applying a wet bandage tightly round the limb, which, when dry, may so com- press the muscles as to prevent the continuance of their contraction ; endeavouring to move the limb during natural sleep, or during that produced by narcotics ; the examination of the limb during the sick- ness and weakness produced by an emetic, or by intoxication, or, better still, by chloroform ; the electric shock; gradual and repeated tension of the contracted limb by means of a pulley or weights ; making a sudden extension whilst the attention is engaged ; applying the actual cautery should that remedy be indicated in the real disease ; or recommending the warm climate of the coast of Africa as a cure. In some cases the most effectual method ©f all is to treat the deformity as a matter of no importance, not requiring surgical treatment. Dislocations may be effected intentionally. Those of the shoulder- joint and patella are the most easily accomplished. Fractures, when real, are often prevented from healing by frequent motion, leading to the formation of false joints. c. Wounds, Ulcers, and Superficial Inflammations. — Mutilation is a very common practice in the army, and especially in regiments sub- mitted to very strict and harassing duties. In countries in which the conscription is in force, the practice is carried to an extraordinary extent. This is the case in France, and to a still greater extent in Egypt, in which unhappy country, it is stated to be difficult to meet with a single unmutilated male adult. Wounds. — The distinction be- tween wounds self-inflicted and inflicted by others, or taking place 138 FEIGNED DISEASES. accidentally, will be considered under the head of wounds. Bruises have been imitated by colouring materials, but not being true to nature they are easily detected by the expeiienced eye. Ulcers are among the most common of feigned diseases, and when they exist naturally they are often intentionally increased. The means most commonly resorted to are corrosive acids and alkalies, caustics, corrosive subli- mate, arsenic and its sulphuret, copper wii'e, acetate of copper, blis- tering plaster, quicklime, the flame of burning bodies, the ashes and chewed leaves of tobacco, the vegetable acrids, especially the ranunculus acris and sceleratus, the mezereon or spurge-laurel, the euphorbium, the arum maculatum, and the juniper. Ulcers are also excited by mechanical means, as by pressure and friction — pressure by pieces of copper coin, and friction by sand. Occasionally in place of being produced or increased by the use of irritants, ulcers are imitated by gluing a portion of a spleen or the skin of a frog on the pai-t, the surface being kept moist by a sponge dipped in blood and water. The most common situation of these factitious ulcers is the lower extre- mities. Factitious ulcers may often be detected by simple inspection of the surface and dressings, or by a closer examination with the lens. The sudden increase of inflammation on and about the ulcer will naturally excite a suspicion of the use of irritants; and the healthy appearance of the impostor will often be found at variance with the extent of ulceration. In hospitals, when there is ground for suspicion that an ulcer is prevented from healing by the use of irritants, a wooden box completely enclosing the leg has been used with the best effect. Fistula in Ano and in Perineo have been imitated by a punctured wound into which a tent covered with some irritating substance, or made of the root of the milk thistle, or of white hellebore, is intro- duced. A variety of cutaneous diseases have been feigned, or inten- tionally produced, as lupus by the application of pounded garlic, and the juice of the euphorbium ; erysipelas by a short application of blisters ; urticaria, by eating shell-fish ; psoriasis and impetigo, by the use of strong rubefacients ; pompjiolyx, by blistering plaster ; scabieSf by punctures irritated with gunpowder; porrigo, by nitric acid dropped upon the hand, and by othe)- irritants ; as also by a paste composed of rancid butter, honey, sulphur, and a small quantity of the powder of cantharides ; baldness has been effected by the use of nitric acid. Variola in its eruptive stage has been imitated by punctures into which bay-salt and gunpowder were afterwards rubbed. The discolouration of the skin in jaundice has been imitated by a variety of colouring materials. To this division belong certain affections of the eyes, which are ob- vious to the senses. Ophthalmia has been purposely produced by gonorrhceal matter, nitric acid, corrosive sublimate, sulphate of copper, nitrate of silver, lime, pepper, snuff, the smoke and juice of tobacco, salt, alum, the powdered root of euphorbium, a blast of cold air, cantharides, friction, and the introduction of fragments of cloth or DISEASES OBVIOUS TO THE SENSES. DISCHARGES. 139 muslin. The counterfeit disease is generally confined to one eye, and that the right : its progress is veiy rapid, the swelling and inflamma- tion are chiefly in the conjunctiva, and cease when tlie vision becomes imperfect. The eye is rarely so much disorganized as in the real ophthalmia. Factitious ophthalmia, when it occurs in the army, is apt to attack only the privates and non-commissioned officers. The use of irritants in the form of powder can often be detected, as in the case of ulcers, by simple inspection. Ophthalmia tarsi has been simulated by the use of strong irritants, or by the extraction of the eyelashes. A healthy aspect of countenance would lead us to suspect the fraud which had been practised, as ophthalmia tarsi rarely occurs in any but the scrofulous and cachectic. Opacity of the cornea has been caused by dropping strong acid into the eye, or by introducing a fragment of lime or of some other strong irritant. Cataract, too, has been produced by the introduction of a fine needle through the cornea to the lens. d. Discharges. Vomiting is a frequent factitious symptom of disease. It is effected by pressing on the pit of the stomach, by swal- lowing air, by a strong and sudden action of the abdominal muscles assisted by tickling the fauces, and by the use of emetics. The matters rejected from the stomach are common water, urine, and even faeces, all of which had been previously swallowed. The larva of insects have also been mixed with substances stated to have been vomited. Factitious vomiting is generally unaccompanied by emaciation, and the fraud is often readily detected by the absence of the other concomitants of those diseases of which vomiting is a symptom. Diarrhoea and dysentery, too, are often feigned or produced at will ; feigned, by breaking down an ordinary evacuation and mixing it with urine ; produced, by a mixture of vinegar and burnt cork, by a solution of the sulphate of iron, by drastic purgatives, or by the introduction of irritating substances into the rectum. The evacuations are sometimes tinged with blood procured by puncture, laceration, or strong suction of the gums, or they are coloured of a dark red by logwood, green by senna, and black by deep-coloured wines. A careful examination of the evacuations, the use of a separate close-stool, the inspection of the linen, and a comparison of the symptoms present with those of the simulated disease, will assist in discovering the fraud. Ascarides have been clumsily imitated, as in an out-patient of King's College Hospital, by pieces of thread, one of which was red. A species of lizard was placed in the evacuations, in a case related by Dr. Spence. Alterations in the secretion of urine belong to this division. Alleged urinary concretions have been found to consist of sand, pebbles, and pieces of quartz and flint. Fragments of brick or slate, and small pebbles, have been introduced into the urethra to bear out the alleged existence of urinary calculus ; and calcined bricks, coals, and fragments of bone have been introduced into the vagina with the like intention.- Mere inspection assisted, in some cases, by chemical tests, will serve to 140 FEIGNED DISEASES. unmask such impositions. Hematuria has been simulated by the use of beet-voot, maddei", cochineal, the Indian fig, the fruit of the prickly pear, and logwood ; blood has also been injected into tlie bladder, or mixed with the urine after it has been passed, or it has been obtained from the mucous membrane of the urethra by scratching. Haematuria may also be caused by substances taken internally, as savin, cantharides, and turpentine. The urine may be tinged of dif- ferent colours by substances taken internally, such as madder, log- wood, indigo, rhubarb, black cherries, the whortle-berry, the pulp of cassia fistula, elder rob, and ferrocyanate of potass, or of iron. Milk has been added to the urine to give it a white colour. In all suspicious cases, the patient should be made to pass urine in the presence of the medical man. The absence of the local and constitutional symptoms attending the more severe affections of the kidney and bladder would naturally excite suspicion, and assist the diagnosis. Gonorrhoea has been imitated by the use of caustics ; the menstrual discharge by staining the linen with bullock's blood ; and Epistaxis has been pro- duced by incisions. Hcemoptysis is a favourite factitious disease. It is imitated by holding in the mouth a sponge filled with blood, by incisions on the inside of the mouth or back of the throat, by pricking the gums, or by blood sucked from other parts of the body ; or pastilles coloured with carmine, Armenian bole, brickdust, or vermilion, have been used for the same purpose. In suspicious cases, the mouth should be carefully examined, and rinsed out with water, the rejected fluid inspected, and, if necessary, analyzed : the chest also should be examined. Hoematernesis is simulated by swallowing the blood of some animal. OtorrJicea is simulated by honey, pus, rancid tallow^ asafoetida, or old cheese, introduced into the meatus : it has been excited by cantharides, or by irritating liquids. Ozoena has been imitated and excited by similar means. Foetid breath and perspiration have been produced by oil of dippel, asafoetida, old cheese, putrifying fish, and the rancid oil from a cart wheel. Emetics in the one case, and ablutions in the other, with careful watching, will serve to detect the imposture. e. Spasmodic affections. This class of diseases is frequently and successfully feigned. Epilepsy is the disease generally chosen for imitation, as it has the peculiar recommendation of being assumed at such times as suit the impostor's convenience. In addition to the violent struggles which form the prominent feature of the true disease, impostors have contrived to inflict bruises upon different parts of their persons as evidence of former attacks, to vomit blood previously swallowed, to imitate the foam at the mouth by chewing soap, and to discharge the urine as if involuntarily. As in the true epileptic seizure there is an entire absence of sensibility, the feigned disease is readily detected by any harmless infliction of pain, or by the use of some powerful stimulant. The stimulants commonly recommended for this purpose are, the vapours of hartshorn, or of sulphur, snuff, pepper, or asafoetida, applied to the nostril ; a few drops of alcohol SPASMODIC AFFECTIONS. 141 or tui'pentine poured into the eye ; a solution of aloes and salt, mustard, or common salt, placed in the mouth ; hot water, or actual flame applied to the slvin. Sharp-pointed instruments have sometimes been introduced into the flesh, but without detecting the imposition. The mechanical stimulus least objectionable, and most likely to be effectual, is the flecking of the naked feet with a wet towel or hand- kerchief. Other diagnostic marks between the true and the fictitious epileptic seizure might be mentioned; but they are of little value in comparison with these direct tests. Convulsions. These irregular actions of the muscles have been rife in all ages, partly as the i-esult of involuntary imitation, and partly as the consequence of imposition. They are most frequent in females ; but are by no means confined to that sex. The chief difference between real and feigned convulsions is that the real may be continued for a long time with comparatively little exhaustion, while the factitious soon occasion fatigue. To discover the fraud "it is sufficient to act with force on the antagonist muscles." (Orfila.) The impostor may also be tired out by long watching. Two cases of pretended local convulsive movements have come under the notice of the author. In one case the muscles of the abdomen were the seat of the contortions; in the other the muscles of the shoulders. Chorea. This, like other forms of convulsion, has often been the offspring of fanaticism, of involuntary imitation, and of voluntary deception. It is more easily feigned than epilepsy. When skilfully imitated the diagnosis is not easy, and many of the distinctions laid down in books are without foundation. Cold affusions and electricity, which may be used with propriety in true chorea, are not pleasant remedies for im- postors, and are therefore greatly to be commended. Hysteria. It is of little consequence whether an attack of hysteria be feigned or not : cold affusion, which is the best remedy for the real disease, is not a pleasant application in feigned attacks. Whether it cures the real disease or leads to the fictitious one being laid aside is a matter of little moment. Catalepsy is a very rare disease, and its existence, especially in a male, may fairly justify some degree of suspicion. Powerful stimulants, the proposal of the actual cautery while the finger is on the pulse, appending a weight to the extended limb and cutting the string suddenly, have been recommended and practised with effect in feigned cases. Attempts have been made to feign te- tanus and hydrophobia but they were unsuccessful. The fingers have been forcibly contracted, and the nails driven into the palm of the hand. By wearying the muscles with a conical piece of wood the imposition is readily detected. Stammering is often feigned. The best distinction is founded on the fact, that true stammerers hesitate little or not at all in repeating what they know by heart, and in singing. Strabismus, Nictitation, and Blepharospasmus are unimportant and easily pre- tended. Dysphagia, when feigned, may be cured by the persevering use of the probang. , The suspected person should be narrowly watched. Stricture of the urethra has been feigned, but as the treat- 142 FEIGNED DISEASES. ment of the real disease is not agreeable, the imposition is not likely to be persevered in. /. Paralytic Affections (Hemiplegia, Paraplegia, and Local Para- lysis). In true paralysis, the parts affected are relaxed and emaciated, and their tempeiature is lowered. In paraplegia, the urine generally undergoes a maiked change. These characters are not piesent in the fictitious malady. Every form of partial paralysis has been feigned. In paralysis of the fore-arm and hand, and more rarely of the entire upper or lower extremity, the discovery of a blue line on the gums would give good grounds for believing the paralysis real. Paralysis agitaiis. In attempting to imitate this disease the impostor generally overdoes his part. It is considered characteristic of the real disease that the patient in attempting to walk "is impelled unwillingly to adopt a running pace." The pretender, on the other hand, is apt to hesitate in his movements and to advance with difficulty. It happens fortunately in this, as in most diseases of this class, that the remedies proper for the disease are not agreeable ones ; and where there is a good ground for suspicion, low diet will be found a useful auxiliary. Ptosis. The impostor generally makes attempts to prevent the raising of the eyelid, and this leads to detection. Insensibility, when feigned, may be detected by the use of stimulants, and the imposition will often be discovered by inconsistent statements as to the cause. Coma and Lethargy have been very successfully feigned, and in one or two instances the impostor has resisted every stimulant that could be thought of: in one case the operation of trephining caused merely a single groan. The treatment which we should be justified in resorting to if the complaint were real would prove a trying discipline to most impostors. Syncope. This scarcely admits of being feigned, for if the impostor can contrive to grow pale, he can scarcely control the action of the heart and arteries. More than one case, howeA''ei-, of a voluntary control over the circulation is on record, of which the best authenticated — that of Colonel Townshend — will be found in the chapter on Real and Apparent Death. Death itself has been feigned, and in one or two cases with such success as to deceive the common observer ; and, in the solitary case of Colonel Townshend, so as to deceive medical men themselves. Poisoning has been feigned in some instances and imputed in others. The same rules apply to the detec- tion of the first class of cases as to the detection of a feigned disease. We must compare the symptoms present with the known symptoms of poisoning generally, or of special poisons. Cases will also be given, under the heads of hanging and drowning, of the fraudulent disposal of a dead body so as that death may appear to have been due to those causes. Among prisoners unreal attempts at suicide by suspension or strangulation are very common. The attempt is usually made when assistance is known to be at hand. The feigned' insensibility which follows is best unmasked by the electric shock. DIMINISHED SENSATION. 148 2. Diseases and defects of a simple kind not obvious to the senses, but depending chiefly upon the description of the impostor. The principal diseases belonging to this class consist in, a, increased and b, diminished sensation. a. Increased Sensation. — Pain. This common symptom of disease is easy to assume and difficult to detect. External pain, such as tic- douloureux, often occurs in persons other wise, to all appearance, healthy ; and there are many pains of a severe character, of which the cause is extremely obscure. Many cases are also on record in which severe pain has arisen from a cause that has escaped observation, and the sufferers have been treated as if the pain were pretended. The nature of the pain, the appearance of the patient, the presence of the symptoms of disease with which it is ordinarily associated, and the consistent ac- count given of its origin and progress, will assist us in distinguishing real from pretended suffering. But great caution and patience are necessary. Remarkable cases are recorded of submission to the most severe and trying remedies, and even to the removal of the breasts and limbs for simulated neuralgic affections. Fain in the head, and the giddiness which often accompanies it, are also easily feigned, and not easily proved to be so. No certain rules of diagnosis can be laid down in this class of cases ; and in the case of pains in the head, as in pains in other parts of the body, real sufferings have been mistaken for pretended ones. Rheumatic pains in various parts of the body, es- pecially in the loins and thighs, are often feigned ; and, as they are not accompanied by any change in the parts affected, or by any well-marked constitutional symptom, with success. In many works on feigned dis- eases, long rules are given for detecting feigned pain, and the symptoms of almost every disease accompanied by pain are detailed with a minute- ness as unnecessary as it is useless ; for it may be stated as a general rule that feigned diseases of the more obscure class can be detected only by those who have extensive experience of real ones. 6. Diminished Sensation. — A diminution or entire absence of sensa- tion is frequently pietended. Amaurosis is a favourite feigned disease, and is often produced intentionally. The substances employed for this purpose are the juice or extract of belladonna or hyoscyamus, the dis- tilled water of the spurge laurel, and snuff moistened with a decoction of belladonna. The amaurosis produced by these means is not at first distinguishable from the real ; but it disappears if the impostor be carefully isolated and watched. Of the perseverance with which the pretence of blindness is sometimes carried out, a case related by Mahon affords a good illustration. A recruit feigned blindness, and, after all other means had been tried without success, he was placed on the bank of a river, and ordered to walk forward, which he did. He afterwards confessed the imposture. Myopia. — Short-sightedness being a disability in the army is often feigned. It may be detected by placing an open 144 FEIGNED DI8EASE8. book close to the face, or by requiring the suspected person to read print at some distance by the aid of glasses for the near-sighted. If the individual cannot read the book when thus placed, or when such glasses are used, we may be sure that the defect is feigned. Presbyopia is i-arely feigned. The mode of detection is the converse of the pre- ceding. ' Ambli/opia, or weakness of sight, is also rarely pretended. In the army, the surest way to put a stop to these pretended defects, is to employ the subjects of them in some service for which the real defect would"^ not unfit them. Nyctalopia. — Night-blindness. This disease is peculiar to warm climates, in which the sun's rays have great power. There are no satisfactoi7 means of distinguishing the true from the feigned disease, as opposite states of pupil may exist in different cases. Here, too, it is useful to find for the real or pretended nyctalope some employment for which the affection, if real, does not incapacitate him. Ifemeralopia, or day-blindness. This disease is not of much imjx)rt- ance. It sometimes ocdurs for a short time as a symptom of worms, or of other intestinal irritation. The diagnosis will depend upon our knowledge of the disease of which it is 3 symptom. Deafness. — As this may occur without any change in the appearance of the external ear, it is a favourite imposition, the modes of detecting it are obvious. A watch should be set on the suspected person day and night, and things calculated to excite interest or apprehension should be said in his pre- sence, and the effect be carefully watched. It has been recommended to place the hand on the pulse while any bad news, or threat of punish- ment, is being uttered. He should be called sharply or unexpectedly by name, or in a whisper, or he should be roused from sleep and spoken to, or a piece of money should be let fall close to him. All these, and similar tests, have often been applied in vain ; sometimes, too, the loudest noises have not produced any apparent effect. In one case, related by Dunlop, a pistol was fired off close to the ear without efl'ect ; but upon the man bemg sent to sleep by opium, the imposition was detected on the repetition of the firing. Dumbness. — This is sometimes assumed with great perseverance. As a general rule it may be stated, that if a man not deaf can move his tongue he is not dumb. Nothing but complete paralysis can account for his being dumb. Some mutes add to pretended dumbness a feigned mutilation of the organ, which they effect by rolling the tongue back into the throat, and scratching it so as to make it bleed. A relative of the author's detected such an imposition in the case of a man who, by means of a written paper describing his captivity among the Algerines and his mutilation by them, had excited great commiseration. Pretending to give entire credence to the man's tale, and taking a half-crown out of his pocket, he requested the man to show him his tongue once more, upon which he thrust his finger suddenly against the root, and the tongue rolled out. Dcaf-dii.mbness. — The combination of deafness and dumbness, though never occurring in a person previously in possession of both these faculties, is sometimes obstinately pretended. The impostor is FEVER. 145 best made to lay aside his imposture by solitary confinement and low diet. In one or two remarkable instances, men who have pretended that they were born deaf and dumb, have resisted every test, and have been discovered only by those having personal experience of the really deaf and dumb. 3. Diseases of a more complicated kind. In the two foregoing divisions those impositions have been considered which consist of a single appearance or outward manifestation, tangible or visible to the senses ; or of a single alleged symptom or defect, not necessarily combined with other symptoms, or which, if sometimes forming part of a disease, deserve separate consideration. It now re- mains to speak of instances in which whole trains of symptoms proper to certain diseases have been assumed, with more or less success. This division consists of two classes : a. Diseases of the body. 6. Diseases of the mind. a. Diseases of the Body. — Fever may be either feigned or purposely excited. Fodere states, that he has often seen impostors produce an extraordinary frequency of pulse, accompanied with chattering of the teeth and profound sighs. Febrile symptoms may be excited by strong stimulants, such as wine, brandy, cantharides ; and by the internal use of tobacco, which drug has a remarkable effect on the pulse ; also by the introduction of a clove of garlic into the rectum. Violent exercise, or strong contraction of the limbs, or a heap of blankets, has been resorted to as a means of imitating fever. The tongue has been whitened by chalk, pipeclay, soap, flour, or whiting ; and tinged brown by tobacco, brick-dust, liquorice, or gingerbread. Pallor of the skin has been imitated by the use of emetics, by smoking, by digitalis, or by drinking an infusion of cumin seeds. A flush, on the other hand, is produced by friction. The detection of cases of simulated fever is easy. The effects are always ephemeral, and all that is necessary is to have the patient watched for a few hours. Ague is often feigned, but not with much success. The effort necessary to imitate the rigors throws the impostor into a perspiration, which leads to detection. The shivering fit is not followed by the other stages. Bheumatism. — The acute form is not easily feigned ; but the chronic form consisting chiefly in pain, and having no strongly-marked accompanying symptoms, has often been, as already stated, imitated with success. Various affections of the chest are assumed by impostors. Pneumonia. — In one instance mentioned by Dr. Gavin this disease was assumed, but not very successfully. The stethoscope would serve at once to prove its non- existence. Phthisis. — It would be diflicult to deceive a careful ob- server, or one skilled in the use of the stethoscope ; but many symp- toms of the disease have been successfully assumed. Heemoptysis and mucous expectoration have been imitated in the manner already de- scribed. Emaciation may be produced by abstinence, by drinking L 146 FEIGNED DISEASES. vinegar, or by sucking a copper coin ; febrile symptoms by the means just pointed out. Asthma, also, has been imitated, but here the stethoscope will assist in the detection of the imposition. Apoplexy cannot be successfully feigned. The fraud is easily detected by ster- nutatories, or by strong stimulants. Dyspepsia. — This disease is often feigned, and sometimes with success. Vomiting, gastralgia, pyrosis, and in fact all the symptoms of dyspepsia have been assumed, and the imposition has been detected only by careful watching. Gas- tritis, or acute dyspepsia, has also been assumed, but it is difficult to imitate it with success. Constant vomiting is not easily feigned, nor is the bright-red tongue, often present in acute gastritis. Peritonitis, too, has been imitated, but rarely with much success. In one case in which there was a pretence of great pain increased by pressure, a dose of opium was given, and the man bore very strong pressure without being roused from sleep. Hepatitis in its chronic form is a favourite feigned disease, as it is very prevalent in hot climates, and is supposed to be of very frequent occurrence in this coimtry. The dull heavy pain in the right side is easily assumed, and the pain in the shoulder, but the discoloured eye and skin, the unhealthy aspect of the counte- nance, and the mental depression and listlessness not so readily. Jaundice has been imitated by staining the skin with an infusion of the root of curcuma longa, or of saffron, with tincture of rhubarb, the bruised seeds of the broom, or the stamens of the iris. Clay-coloured stools have been produced by taking a small quantity of muriatic acid, and the colour of the urine has been heightened by rhubarb. Attempts have also been made to pass off pebbles for gall-stones. It is notreasy to tinge the conjunctiva yellow, nor to produce at one and the same time the yellow skin, the pale stools, and the highrcoloured urine. It must be borne in mind, however, that in the real disease the fseces are not always pale, but that occasionally they contain an excess of bile. Scurvy. — One prominent symptom of this affection is often imitated, viz., the spongy and bleeding gums. For this purpose, various irri- tating substances are used, or the gums are punctured previously to the visit. As this is but one symptom, and the otheis are not easily feigned, this imposition will present but little difficulty. Nephritis. — The pain which accompanies this disease has been assumed, and the assertion has been borae out by the exhibition of pebbles or fragments of brick. It is scarcely necessary to state that it is almost impossible for an impostor to assume all the symptoms of nephritis. Much more might be said on this division of feigned diseases, and minute rules for diagnosis might be laid down : but want of space, and the assurance that it is not by descriptions of diseases, but by actual experience of them, that the true are to be distinguished from the false, has led to the subject being thus briefly handled. Those who are familiar with treatises on this subject will know how much of false diagnosis they contain. In doubtful cases, a reference to the best description of the disease supposed to be assumed is strongly recom- RULES FOR THEIR DETECTION. 147 mended, but it must be borne in mind that symptoms commonly con- sidered as of high diagnostic value may be absent in the real affection, and may lead to unjust suspicions. h. Mental Disorders. — Feigned insanity is of so much importance that it will be treated in the next chapter under the head of unsound- ness of mind. The following general rules may render some assistance in distin- guishing a feigned disease from a real one. RULES FOR THE DETECTION OF FEIGNED AND FACTITIOUS DISEASES. 1. Inquire, in all cases, into the existence of motives for deception. Will the suspected person, by imposition, gain anything he desires, or escape anything he dreads ? It should, however, be borne in mind that both men and women feign diseases from other motives than those of gain ; and occasionally there is so complete an absence of all discoverable motive, that we are forced to believe in the existence of a moral insanity displaying itself in this way. 2. Inquire into the previous history of the patient, and the character he bears among his comrades or companions. It often happens that the impostor has been previously noted for dishonesty, and for prac- tices similar to those of which he is suspected. But, in other instances, men of the best character, who have for years conducted themselves with propriety, have been convicted of malingering. 3. In the case of external diseases obvious to the senses, make a minute and careful inspection of the part itself, and examine it by the eye and by the touch. When there is a suspicion of the use of irri- tating substances, inspect the part narrowly with the aid of the lens, and search the pockets, boxes, or bed of the suspected party, and if necessary isolate him so as to deprive him of the assistance of others, and of his means of deception. Use equal care in inspecting substances alleged to have been discharged, and examine them, if necessary, by the microscope or by chemical tests. In cases of rigidity, anchylosis, or deformity, examine the suspected person when under the influence of chloroform. 4. When some defect, or disability not obvious to the senses, but depending entirely upon the assertion of the person himself, as pain, deafness, &c., is supposed to be assumed, we must endeavour to take him by surprise. In the case of pretended deafness, for instance, we must try to discover the imposition by sudden and unexpected noises, by speaking to the suspected person immediately on his being roused from sleep, or when his power of self-control has been impaired by opium or chloroform. 5. In cases of feigned diseases, properly so called, we must examine minutely into the history and alleged causes of the disease ; compare the age, temperament, and mode of life of the suspected person with 148 FEIGNED DISEASES. the symptoms present ; watch narrowly the course of the symptoms, and contrast it with the known march of the disease itself. 6. The suspected peison should be visited at all hours of the day, and at times at which he does not expect to be seen ; and he should be watched by those whom he is not likely to suspect. 7. The questions addressed to a suspected person should be of a nature to mislead him : they should be so framed as to lead him into the assumption of symptoms foreign to the malady which he is simu- lating. By concealing the suspicions really entertained, and foretelling, in the hearing of the suspected person, the advent of symptoms which do not belong to the assumed disease, the malingerer may often be made to betray himself. 8. Observe whether the suspected person is willing to make use of the medicines and measures prescribed for his relief. The impostor is generally less disposed to resort to the necessary means than he who is really ill. 9. Great caution is necessary in the treatment of suspicious cases. As a general rule, no measures ought to be employed which would not be justifiable on the supposition of the disease being real. But when thei e seems to be strong ground for suspicion, low diet, isolation, and nauseous medicines may be fairly resorted to. When the disease sup- posed to be assumed is one which does not affect life (such as spasmodic twitchings of the muscles), it will often suffice to treat it with indif- ference, and to dissuade the suspected person from having recourse to medical treatment. Persons who wantonly abstain from food will generally desist if allusion is made in their hearing to cases of pro- longed abstinence; and those who refuse to take exercise may be influenced by being placed on a lower diet. Closely connected with the subject of feigned diseases is that of disqualifying diseases. It is chiefly interesting to military and naval surgeons; but cases occasionally occur in civil life in which the medical man is required to state his opinion.. He may be directed to ascertain whether an individual is fit to serve on a jury ; whether he is able to attend as a witness ; whether he is competent to take on him certain offices or duties ; or whether he can bear hard labour, or other severe punishment, which he may be sentenced to undergo. The medical man may also be called upon to ascertain the state of health of persons wishing to effect insurances upon their lives, and of children presenting themselves for admission into some of our public schools. The subject of exemption on the gi-ound of disquali- fication in civil and criminal cases scarcely requires, or admits of, any precise rules ; and disqualification for military service is a subject of too great extent to be treated of usefully in this place. There is the less necessity for its introduction here, inasmuch as the military surgeon is required to possess some work on his recruiting duties. The foregoing obsei-vations on feigned and factitious maladies apply equally to malin- gerers in the army and skulkers in the navy as to impostors in civil life. 149 CHAPTER V. UNSOUNDNESS OF MIND. The occasions on which the medical man may be required to give evidence as to the condition of the mind are very numerous. A man makes a will, and his relations dispute its validity : was the testator, at the time of making the will, in full possession of his faculties ? A man squanders his property, or is accused of so doing : is he competent to manage his affairs? A man or woman contracts an unsuitable marriage : was the party possessed of such an amount of intellect, or in such a state of mind, as to give a valid consent to the contract ? A criminal, or a person under accusation, makes a confession: was he in a sound state of mind when he made it ? An act of great atrocity is committed : is the man who committed it in such a state of mind as to make him responsible for his act ? A criminal is supposed to feign insanity in order to escape from the consequences of his crime : is he really of unsound mind ? That these questions are of frequent occur- rence may be inferred from the fact that the ascertained number of persons of unsound mind in England and Wales does not fall much short of 35,000. The medical man may be summoned to give evidence on the state of a person's mind before any of our courts of law, civil, criminal, or ecclesiastical ; before commissions technically designated de lunaticQ inquirendo ; and in the case of pauper lunatics, before the magistrate. He may also be called upon to sign certificates of unsound- ness, at the instance of private persons, with a view to provide for the safe custody of those who are either unable to take care of themselves, or so afflicted as to be dangerous to society. All inquiries into the state of the mind are surrounded by peculiar difficulties — difficulties partly inherent in the subject itself, partly due to the requirements of the law. The difficulties inherent in the subject itself arise, in part, out of the great original differences between mind and mind, the various degrees of development which they derive from education, and the equally various degrees of restraint to which they are subject in each period of life. Other sources of difficulty are to be found in the purely inferential character of our knowledge of the human mind, in the inapplicability to it of the method of experiment, in the want of any recognized standard of sanity, and in the necessity under which we are all placed of erecting our own mental experience into^, standard to which to refer the operation of other minds. Minds thus different in original power, and in acquired habits, are known to be variously afi'ected by the same physical and moral causes, and to be 150 UNSOUNDNESS OF MIND. subject to many distinct forms of disease displaying themselves in lan- guage and acts of the most vaiious character. J^ome part of the difficulty which surrounds this subject is also to be attributed to the undue importance formerly given, in works on the human mind, to one or two of its higher faculties. The reason and the imagination were put so prominently forward, and the emotions and passions were made to play so subordinate a part, that soundness and unsoundness of mind came to be regarded as almost synonymous with a sound or erring reason ; imagination had to bear all the blame of misleading the judg- ment ; and delusion became the favourite test of insanity. A more simple and practical theory of the human mind, recognizing the existence of several distinct faculties, has now taken the place of the narrow speculations of the older metaphysicians ; and this theory of separate faculties, originally of different power in dilTerent persons, more or less improved by education and habit, under greater or less restraint fiom without or within, subject to different degrees of excite- ment ; from causes acting within the body itself or from without, som'^times alone and sometimes in combination, is the theory which best agrees with reason and experience, offers the readiest explanation of the almost infinite variety of character, the endless diversities of opinion, and the strange eccentricities of conduct prevailing among mankind, and is most in harmony with what we know of the unsound mind. The difficulties due to the requirements of the law originate in part from the lawyer's necessary ignorance of the unsound mind, the narrow views which have been handed down to him upon the subject, and the arbitrary selection of tests difficult, if not impossible, of application. The medical witness is accordingly often asked to define that which is properly a subject of description, and is tortured with questions which if he ventures to answer according to his belief, he lays himself open to the charge of presumption, if not of impiety. In discussing the subject of unsoundness of mind, it is important to premise that it is not possible to frame a single definition of that state, nor to present a just view of it in a single description. For mental unsoundness assumes many shapes, and admits of many divisions and subdivisions, with a coi'responding nomenclature. In searching after a just classification and an appropriate nomenclature, it is desirable to adopt, as far as practicable, the divisions and names sanctioned by legal usage. Wherever, then, the law defines with precision the meaning of the terms it uses, those terms will be preferred ; and where no fitting word has been provided characteristic of a given state of the unsound mind, that will be employed which is in most common use by the best medical authorities. In searching for a term proper to designate all departures from the more usual state of the mind, we necessaiily encounter the woids *' mad" and " insane," descriptive of the person affected, " madness" and " insanity," descriptive of the state of the sufferer. These terms ITS VARIETIES. 151 might be adopted at once if they were commonly employed as the exact opposites, respectively, of the words " sane" and " sanity." But they are generally used in a restricted sense, as applied chiefly to those deviations from the healthy condition of the mind which consist in excessive and disproportioned activity, and are rarely, if ever, applied to those states of mind characterized by deficient energy of action, whether original or acquired. It is necessary, therefore, to make choice of terms which, being in less common use, may be more easily restricted in their meaning. Such are the terms " Unsoundness of mind" applied to the condition of the mind itself, and " Non compos mentis" applied to the person whose mind is affected. But even these two terms are not free from objection, for the term "Unsoundness of mind" has not been always employed by legal authorities in a strict and limited sense. In the Portsmouth case, for instance. Lord Eldon spoke of unsoundness of mind as a state re- quiring to be distinguished both from idiocy and lunacy, and in many statutes it is found associated with the words Idiot and Lunatic. The term " Unsoundness of mind," then, which seemed so simple and intelligible, is open to serious objection : but as it is to be preferred to the term Insanity, or to any other in common use, it has been placed at the head of this chapter. The other term, " Non compos mentis," applied to persons who are of unsound mind, has been used by legal authorities with much greater consistency, and should be employed in preference to all others. Having thus made choice of a term comprehensive enough to include all deviations from a sound condition of the mind, we have next to inquire what the law includes under this term, non compos mentis, what forms of unsoundness it recognizes, and how far it may be con- sistent with our knowledge as medical men to adopt a subdivision in accordance with the legal terms in most common use. The common law of England originally included under this term only two forms of unsoundness, viz.. Idiocy and Lunacy, but the highest legal authorities have acknowledged the necessity of more minute subdivisions. Thus Lord Coke recognizes four sorts of non compos mentis. — " 1. Idiota, which from his nativitv by a perpetual infirmity is non compos mentis. 2. He that by sickness, grief, or other accident wholly loseth his memory and understanding. 3. A lunatic that hath sometime his understanding, and sometime not, aliquando gaudet lucidis intervallis, and therefore he is called non compos mentis, so long as he hath not understanding. Lastly, he that by his own vicious act for a time depriveth himself of his memory and under- standing, as he that is drunken." We have here distinctly recognized three forms of unsoundness of mind, Idiocy, Dementia, and Lunacy, of which the first two alone are sufficiently well defined and understood to admit of being employed both by lawyers and physicians as part of a classification of the forms of mental unsoundness. The term lunacy is objectionable, inasmuch 152 UNSOUNDNESS OP MIND. -g I'd s •- ^ :s ^^^§-55 3 «-2'5s= g sz: % 3 OT l« C '-4- Jj g O) C <1) o -^ = ?l sill 1^1 £ ^'p »■ ^ ^ .s g >, s fS ^ •g I § S .^ S ^ 2 o S •. 8 » „ c: j,.^^ o ^ « « « ^- § -^ -3 ■£ g -^ g - -g 5 II i'^ 1111111 1 i i 1 c .§ is" « « 2 1 = a .2 s pH - s t^^ ^ -r 1^1 a ||.>|§ 'A pi ^ 0, S fl rt a;^ 53 - -►^ _ 'i: bfj^ ^ r r-. >^^ Q^ C3 CO O O 2 "3 ^ .i; S £ -^ -S -c g . ^:3 9 bc-g S ■= o Qj^ c= « -w - ^ C ^ '^ c "^ I' 3^ 5 "■ o o) ~ -c 'TS 3 =^ a § o >.2 .- ..Kill SPECTRAL ILLUSIONS. 153 As the subject of unsoundness of mind is one of vast extent, and embraces a great amount of details, a methodical arrangement of it is absolutely requisite. It is proposed to treat it under the following heads: — 1st. Of certain unusual conditions of the mind not included under the general term mental unsoundness, and of the phenomena of dreaming. 2. Of certain condftions of tlie mind allied to mental unsoundness, but produced by temporary causes, viz. delirium, de- lirium tremens, drunkenness, and the effects of certain poisons. 3. Of the several forms of unsound mind, treated in the order in which they stand in the foregoing table. 4. Of some of the more important chai-acters of the unsound mind, and of the medical and legal tests of that unsoundness. 5. Of feigned unsoundness of mind. And, lastly. Rules for the examination of persons supposed to be of unsound mind. 1. OP CERTAIN UNUSUAL CONDITIONS OF THE MIND NOT IN- CLUDED UNDER THE GENERAL TERM MENTAL UNSOUNDNESS. The subjects included under this head have a close connection with, and direct bearing upon, unsoundness of mind. Dreaming is very generally recognized as an analogue of insanity. Spectral and other illusions exist in most forms of mental unsoundness ; and the acts of the somnambulist are occasionally such as to originate questions of a medico-legal nature. Spectnil illusions. — Some individuals have possessed the power of recalling at will impressions made on the senses, so as to place the objects before them afresh ; others have enjoyed a still more enviable power of converting thoughts into sensations, if such an expression may be allowed ; and others again, in moments of intense excitement, or under the influence of slight derangements of their health, have seemed to see or hear things which had no real existence.* Spectral illusions, as has been just stated, are of common occurrence in some fonns of mental unsoundness, and their presence serves to explain, at least in part, the obstinate belief by which the mind, in such cases, is possessed. Thus the author of a curious and interesting autobiography, f which receives strong confirmation from the state- ments of persons who have been similarly afflicted, says in reference to one of his many spectral illusions : '* I imagined I was really present to them ; and that my not acknowledging it was a delusion, an obstinate resistance of the Divine will on my part. That of the two, the appearance of the bed, walls, and furniture, was false, not my preter- natural impressions."! * For examples, see Sir David Brewster's ' Letters on Natural Magic,' Sir Walter Scott's ' Demoriology and Witchcraft,' and Brierre de Boismont ' On Hal- lucinatioiis.' f ' A Narrative of the Treatment experienced by a Gentlemen during a state of Mental Derangement,' page 63. 154 UNSOUNDNESS OF MIND. Spectral illusions, then, are common to men of sound and of unsound mind, the diH'erence being, that the former do not believe in their reality, the latter do. The sane man corrects these false impressions by the use of the other senses, or by some effort of comparison, while the man of unsound mind neglects these simple means of undeceiving himself, or cannot use them ; or if he is led to entertain any doubt, he dispels it by the help of his delusion. Thus, the author of the auto- biography, whose unsoundness of mind took a strong religious turn, thought it impious to doubt. The subject of illusions of the senses came into discussion in the recent case of Buranelli, and questions were put to the medical witnesses as to the proper definition of the terms illusion and delusion. The difference between them is best shown by the addition of three words to each : — an illusion of the senses, a delusion of the mind. It may be well to add that an illusion of the senses, if believed to be a reality, becomes a delusion of the mind. The term spectral illusicm is synonymous with the word phantasm. The term hallucination might be dispensed with altogether. It is not needed ; and as it means an erroi-, blunder, or mistake, it has no proper place in descriptions of mental unsoundness. An illusion means a mockery, false show, or counterfeit appearance ; and a delusion a chimerical thought. The word illusion may be applied, with equal propriety, to a sensation without corresponding object, to a transformed appearance of a real object, or to an internal sensation exaggerated or misinterpreted. But M. Brierre de Boismont uses the term hallucination to designate an unreal sensation wholly due to the action of the brain, and illusion to designate a real sensation exaggerated or distorted by the same opera- tion. The single term illusion ought to suffice for both purposes. Dreaming. — The phenomena of dreaming have a striking analogy to those of some forms of unsound mind. The external world being shut out, and the higher faculties of the mind being in a state of com- parative inaction, illusions have all the vivid impress of reality, and the thoughts which pass through the mind produce the same impression as in our waking state. They also follow each other according to asso- ciations over which we have no control. Many dreams are directly traceable to bodily conditions which are recognized in the waking state as productive of pain or uneasiness, such as an oppression at the stomach, a distension of the bladder, or an inflammation or irritation of the skin. Sometimes this uneasy sensation is distinctly perceived by the sleeper, but attributed to a wrong cause, and associated with imaginary events. Thus Dr, Reid relates of himself, that "the dressing applied after .a blister on his head, having become ruffled so as to produce considerable uneasiness, he dreamt of falling into the hands of savages, and being scalped by them." In other instances, the uneasy sensation gives rise to a dream which has no other relation to the sensation itself than that of being painful PHENOMENA OF DREAMING. 155 or disagreeable. The most distressing dreams of this class are known as nightmares. In another class of cases, the bodily uneasiness seems to have no other effect than that of bringing the mind into a condition favourable to the blending together of disconnected occurrences, sometimes recent sometimes remote, having nothing in common but the feeling of annoyance or discomfort. We hear, perhaps, of a distressing accident; we have received some unpleasant news of an absent friend ; and we have been concerned in some business which gave rise to anxiety : a dieam takes place in which all these are combined together; we are ourselves connected with the accident; the absent friend is in our company; and the person with whom the business is transacted also appears on the scene.* A curious fact has been observed with regard to dreams excited by one class of bodily sensations, viz., that the same sound which awakes the sleeper, occasions a dream that appears to occupy a considerable time. Thus, " a gentleman dreamed that he had enlisted as a soldier, joined his regiment, deserted, was apprehended, carried back, tried, condemned to be shot, and at last led out for execution. After all the usual preparations, a gun was fired ; he awoke with the report, and found that a noise in an adjoining room had both produced the dream and awakened him." The strong analogy which exists between the phenomena of dream- ing, and of certain forms of unsound mind, is shown in the examples cited at p. 181. The remarkable analogy between dreaming and insanity, and the way in which the one may pass into the other, is well illustrated by the case of a maniac, mentioned by Dr. Gregory, who for a week after his recovery was harassed, during his dreams, by the same rapid and tumultuous thoughts, and the same violent passions, by which he had been agitated during his insanity. The case of M'N'aughton may perhaps be cited as bearing a close resemblance to one class of dreams. The refusal of his father to take him into partnership originated in his mind a sense of hardship and injury : the Roman Catholics, the Police, and the Tories, being successively the theme of newspaper abuse, and being also represented as guilty of acts of injustice, impressed his mind with the same feeling. Hence the long dream of years, in which the sense of public injury was transferred to himself, till he became the fancied object of political persecution. The difference between dreaming and insanity is, that in the one, the senses are closed to outward objects ; in the other, the evidence of * ' Inquiries concerning the Intellectual Powers, and the Investigation of Truth.' By John Abercrombie, M.l>. The reader is referred to this work for many instructive anecdotes referring to this subject; and for more full informa- tion on the physiology of the human mind, to the chapter on Mental Physio- logy and Pathology in the author's edition of. Hooper's ' Physician" s Vade 156 UNSOUNDNESS OF MIND. sense is disregarded, or the senses merely suggest trains of wild and fanciful association, objects truly perceived being perverted and mis- interpreted by the help of the prevailing delusion. In dreaming, as soon as the pei-son is roused from sleep, and the external world is again brought before him, all his illusions and delusions vanish; but the madman is in a waking dream, from which he is not to be roused. Legal relations of Dreaming. — A question of criminal responsibility arises in those rare cases in which a man suddenly aroused from sleep kills another. Such was the case of Bernard Schedmaizig, who suddenly awaking at midnight thought he saw a frightful phantom, and receiving no answer to his challenge twice repeated, but imagining that the phantom was advancing upon him, and having altogether lost his self-possession, raised a hatchet which was beside him and attacked the spectre. It was found that he had murdered his wife. Kay also relates the case of two men, who being out over night in a place infested with robbers, engaged that one should watch while the other slept ; but the former failing asleep, and dreaming of being pursued, shot his friend through the heart. A pedlar, who was rudely aroused from sleep by a passer-by, ran him through the body with the sword of a sword stick. He was found guilty.* In all such cases, the con- fused state of the mind on being suddenly aroused from sleep ought certainly to be considered'as a mitigating circumstance. Somnambulism. — This is a form of dreaming in which the senses and voluntary muscles participate ; the one exercised with extraordi- nary acuteness on the subject-matter of the dream, the other obeying the mandates of the sleeper's will with unwonted precision. The somnambulist's mind during the dream is so concentrated upon one object, that his reason or fancy will accomplish that to which it was unequal during his waking hours. It is this complete attention to one object, too, which probably accounts for that extraordinary acute- ness of the senses, that precision of movement, and that total absence of fear which marks the most astonishing feats of the somnambulist ; such as walking on the edge of a precipice, swimming a rapid stream, or riding at full gallop. Sometimes the sleep-walker performs, at each recurrence of the fit, with all the precision of his waking hours, some routine duty. Objects of sense presented to the sleep-walker, either produce no effect, or they are mixed up indistinctly with the dream which he is acting. In some cases, so complete is the mind's abstraction, that the loudest noises are unheeded ; in others, those things only are attended to which haimonize with the existing train of thought. The somnam- bulist is either unconscious of what has occurred, or he remembers it as a dream. In some cases, that which has transpired in one fit of • The first ami last of these cases are quoted by Dr. Forbes Winslow in his • Plea of insanity in Criminal Cases,' the first from Dr. Pagan, the last from the • British and Foreign Medical Review.' SOMNAMBULISM. 157 sleep-walking is distinctly remembered in subsequent ones, but quite forijotten in the intervals. The analogy already pointed out as existing between dreaming and insanity may be extended so as to embrace some cases, at least, of som- nambulism; for in certain forms of both these ali'ections there is a remarkable increase of talent ; in both there may be a complete change of character ; and it would not be incorrect to state, that there is an intellectual and moral somnambulism, as there is an intellectual and moral insanity. The following cases may be adduced in support of this view. A Carthusian monk who, while awake, was remarkable for his simplicity, candour, and probity, walked almost every night in his sleep, and was a thief, and a plunderer of the dead. A pious clergyman, in his fits of somnambulism, would steal and secrete whatever he could lay his hands upon, and on one occasion he even plundered his own church. In one case the somnambulism took the form of suicidal mania. The paroxysms occurred every night, and watchers were required, as if for a patient labouring under an acute disease. He always attempted to escape ; and one night having succeeded, he was found suspended by the feet, from the limb of a high tree.* The following case of homicidal somnambulism is quoted by Georget from an anonymous work. A monk late one evening entered the foom of the prior of the convent, his eyes open but fixed, his features contracted into a frown, and with a knife in his hand. He walked straight up to the bed, as if to ascertain if the prior were there, and then gave three stabs, which penetrated the bed-clothes and a mat, which served the purpose of a mattress. He then returned with his features relaxed, and an air of satisfaction on his countenance. The next day, on being questioned, he confessed, that having dreamed that his mother had been murdered by the prior, and that her spirit had appeared to him and cried for vengeance, he was transported with fury at the sight, and ran directly to Stab her assassin. Shortly after he awoke, covered with perspiration, and rejoiced to find that it was only a dream. f Legal Relations of Somnambulism. — A question has been raised as to the responsibility of the somnambulist for acts committed during the paroxysm, and it has been attempted to be shown that, as that which is done during the fit is often only the accomplishment of a project formed while the party was awake, he ought to be held responsible. If this improbable assumption were true, the somnambulist would not be responsibile unless it could be shown that he was voluntarily accom- plishing in the fit that which he had previously thought about ; in other words, that he became a sleep-walker at will, which is an absurd sup- position. If the question of responsibility should arise it should be shown that the sleep-walking was real and not feigned, and also that the accused was subject to these fits. * • A Treatise on the Medical Jurisprudence of Insanity.' By J. Ray, M.D. f Georget, 'Des Maladies Mentales,' p. 127. 158 UNSOUNDNESS OF MIND. Ecstasis, or cataleptic sotnnambulism, which is nearly allied to hys- teria, and almost invariably occui"s in females, may be noticed in this place. For some interesting cases of it, the reader is referred to Dr. Abercrombie's work on the Intellectual Powers. 2. OF CERTAIN CONDITIONS OF THE MIND, ALLIED TO MENTAL UNSOUNDNESS, AND CAUSED BY DISEASE, OR BY THE OPERA- TION OF CERTAIN POISONS: NAMELY, DELIRIUM, DELIRIUM TREMENS, AND DRUNKENNESS. Delirium. — This state of noind supervenes in the course of almost all severe febrile and inflammatory diseases, and especially of those which attack the internal viscera. It is a common sequence of severe acci- dents, and of surgical operations ; and it often ushers in the fatal termination of chronic disorders. The delirium of fever is generally preceded by pain and throbbing in the head, heat of the scalp, and flushing of the cheeks ; but it some- times makes its attack suddenly, without previous warning. In the first class of cases delii-ium is often preceded by dreaming. The patient talks in his sleep, and wakes up confused and forgetful ; but when fully roused, he is collected, and so remains till the next slumber. By degrees this disturbed sleep passes into waking delirium. The patient lies on his back, dull and listless, with eyes half open, mutter- ing to himself, unconscious of persons or things around him, and when roused scarcely recognizing them. As the disorder inci'eases and the strength fails, the voice becomes more indistinct, the fingers are con- stantly picking at the bed-clothes, the evacuations are passed uncon- sciously, and the patient can no longer be roused to any effort of attention. If delirium occurs at an earlier stage of the disease, or before the strength of the patient has been much impaired, the symptoms are somewhat modified. The eyes are bloodshot, and intently fixed as if on some object really present. The patient talks loudly and earnestly, tosses restlessly about in bed, and makes repeated attempts to leave it, sometimes escaping from the custody of attendants, displaying gi-eat strength and activity, and even committing acts of fatal violence. In some cases, during attacks of delirium, the memory of things long past becomes wonderfully active, and languages which were quite forgotten are recollected and spoken with perfect fluency. In fatal cases, delirium usually passes into coma, but occasionally it disappears some hours or days before death, and leaves the patient in full possession of his faculties. Delirium is a leading and almost constant symptom of poisoning by belladonna, henbane, and stramonium; a frequent result of poisoning by other members of the class of narcotico-acrids ; an occasional one in poisoning by the pure narcotics, and it may even occur from the opera- tion of poisons belonging to the class of irritants. Delirium bears a close resemblance to that form of unsound mind DELIRIUM TREMENS. 159 which goes by the name of incoherence ; and the distinction between the two is not always easily made, without some inquiry into the history of the case. Delirium, when not caused by poison, is a symp- tom of some well-marked bodily disease, while unsoundness of mind is rarely accompanied by bodily disorder, till it has lasted so long as to become associated with paralysis. Legal Relations of Delirium. — Civil acts performed during an access of delirium are necessarily void, and criminal acts entail no responsi- bility. In determining the validity of wills made by patients labour- ing under diseases attended with delirium, the law has regard less to the proved existence of a lucid interval, than to the character of the will itself. If it be in keeping with the patient's known character, and in harmony with intentions expressed or instructions given when he was sound in mind and body ; if the several parts of the will are consistent with each other ; if no improper influence was brought to bear upon him ; the will would be declared valid, even though the medical evi- dence threw doubts on the testator's capacity. On the other hand, in the absence of these conditions, the will would generally be declared invalid, in spite of the strongest evidence of the testator's capacity. It is important to distinguish delirium, with intervals of perfect con- sciousness, from the calmness of demeanour sometimes assumed by patients labouring under strange delusions, the result of unsoundness of mind showing itself in the first stage of convalescence from fever or other acute disease ; or as part of delirium tremens brought on by drinking. The distinction is et\sily made, when it is borne in mind that in the one case (delirium) the mind wanders during sleep, in the other case while the patient is evidently wide awake. Delirium Tremens. — The delirium of drunkards is easily recognized by the peculiar foi-m which the mental unsoundness assumes, and by the equally characteristic bodily symptoms, aided by the previous history of the patient ; and, in most cases, by the prompt cure effected by the proper remedies — stimulants and opiates. A patient suffering from delirium tremens is restless, sleepless, timid, suspicious, and cunning. He is subject to illusions of the senses, and fancies himself surrounded by hideous and loathsome objects, such as toads, serpents, and scorpions, and that he is persecuted by strange sounds and threatening voices; or he thinks that thieves or evil spirits are breaking into the house. When under treatment, he is suspicious of the persons in attendance, and is constantly endeavouiing to make his escape ; and, if not properly watched, may do violence to himself or others. Some patients display a painful eagerness to go somewhere, or do something upon which their minds are bent. The bodily symptoms consist of the tremor from which the disease derives its name, with a pale, cold, clammy skin, a moist, white, tremulous tongue, and a small weak pulse. The history of the case is that of a course of intemperance terminated by a short supply of spirituous liquor, or by some exhaust- ing disease or surgical injury. 160 UNSOUNDNESS OF MIND. In the milder forms of the affection, the patient goes about as usual, answers questions collectedly, and converses rationally ; but when left to himself, he is as one in a waking dream, speaking of things calcu- lated strongly to excite the feelings and passions with a manner per- fectly free from excitement. Some cases of delirium tremens, however, are accompanied by strong excitement, so as to present the closest resemblance to cases of moral mania, the patient being impelled to acts of violence against himself and others by the most unfounded delusions. This class of cases is most commonly brought about by a few days or weeks of continuous hard drinking ; or they occur, as the result of a single debauch in men who have had previous attacks of mania, or of inflammation of the brain, or who have suffered from severe falls or blows on the head. Such cases as these while they last are not to be distinguished from cases of mania. Prolonged abstinence, too close attention to study or business, and solitary confinement, sometimes bring on a state of mind closely allied to delirium tremens, and characterized like it by illusions of the senses of sight and hearing. Legal Relations of Delirium Tremens. — As delirium tremens is a temporary form of unsoundness of mind produced by a peculiar exciting cause, its legal relations must be those of insanity, unless the nature of the exciting cause constitutes it an exception to the general rule. This it does not appear to do ; for, though drunkenness has little effect on civil or criminal acts, delirium tremens is allowed to have the same eflfect as insanity itself. Drunkenness. — The excitement which, in persons of sound mind, attends the indulgence in alcoholic liquors, is converted, in persons of unsound mind, into maniacal incoherence, not to be distinguished from mania arising from other causes, except by the history of the case and the evidence of the sense of smell. A craving after spirituous liquors constitutes, in some persons, a form of unsoundness of mind (dipso- mania) ; while in other persons it is merely one of the leading symp- toms of an existing mental unsoundness. In some cases the craving after alcoholic liquors assumes an intermittent character, showing itself only at intervals. Legal Relations of Dnmkenness. — Drunkenness has no legal effect on any offence to which it leads. It neither increases nor mitigates the penalties which attach to it. Drunkenness has even been deemed an aggravation of the offence. A drunkard's acts are therefore valid, luiless it can be shown that the drunkenness was procured by another person with a view to an unfair advantage. The question of the responsibility of persons suffering from the disease now recognized as dipsomania must be decided by the same tests as are applicable in other forms of unsoundness of mind. AMENTIA. 161 3. OF THE SEVERAL FORMS OF UNSOUND MIND. On referring to the table at p. 152, it will be seen that the several forms of unsound mind resolve themselves into three leading classes — Amentia, Dementia, and Mania. This form of unsoundness of mind comprises the two species, idiocy and imbecility, as well as those cases of originally defective intellect which are traceable to local causes and are known as cretinism. Idiocy. — The best legal and medical writers agree in defining idiocy as a congenital malady, and the idiot as one " who from his nativity by a perpetual infirmity is non compos mentis" But some writers of both professions have used the term with less precision, evidently con- founding the idiot with the victim of dementia, or even of mania. The time for such confusion of terms is now past, and there is a clear under- standing that idiocy is a congenital absence or serious defect of all the faculties of the mind ; but a state admitting of degrees, and, like other forms of unsoundness of mind, not allowing of strict definition. Idiocy, in its lowest form, combines the extreme of bodily deformity with an existence purely vegetative. Such idiots seem devoid even of sensation, and would perish if not closely attended to. In a somewhat higher form there are sensations of heat and cold, of hunger and thirst, and just intelligence enough to indicate the commonest wants by signs. But these are equally helpless with the first class. A still higher class consists of those idiots who have sensation and consciousness, recognize familiar persons and objects, are susceptible of attachment, can move from place to place, are able to make known their wants by gestures and sounds, or even by words imperfectly articulated, can be made to acquire habits of decency, can learn to hum or sing, or even to perform the simpler operations of arithmetic, and are susceptible of a certain limited improvement of their bodily and mental condition under careful, assiduous, and skilful teachers. As a general rule, idiots are deformed in body as well as stunted in intellect. They have small and misshapen heads, squinting eyes, large gaping mouths with thick lips, and other features ill formed and dis- torted. The limbs and trunk are also imperfectly developed, and their gait is awkward and unsteady. Their complexion is generally sallow and unhealthy. Some of their senses are altogether wanting, and others very imperfect. In a few exceptional cases, the head is of ordinary size and well formed, and the body is not distorted, but the expression of the face is that of complete vacuity. Idiots who reach the age of puberty often display the sexual passion by offensive gestures and disgusting habits, and they are also subject to violent fits of passion, and sometimes commit acts of atrocious cruelty. 162 UNSOUKDNESS OF MIND. Tlie Legal Relations of Idiocy, in the restricted sense here assigned to the term, are very obvious. The persons now described labour under complete civil disability, and are irresponsible. Im^jecility. — This term is here used to designate unsoundness of mind occurring in early childhood, as contradistinguished from that which is congenital. This distinction is in accordance with the legal definition of idiocy ; and it has the advantage of separating the idiot who has no use of speech, in consequence of his brain at birth being so defective a.s to prevent him from being taught even to this limited extent, from those who, being born with a better conformation of brain, are able to acquire the use of speech. A distinguished writer on Mental Unsoundness, M. Georget, recognizing this distinction, describes the imbecile as persons who have some use of speech, and who display some indications of mind, of intellectual faculties, and of feelings and affec- tions. In strict propriety of language, perhaps, idiocy and imbecility should be equally characterized as congenital defects, of which the more marked (idiocy) makes itself soonest known, while imbecility is not recognized till the faculties have been tested by education and found wanting. It is also obvious that it is not possible to draw a sharp line of distinction between the idiot and the imbecile. The fainter shades of imbecility pass into the lighter tints of idiocy. But the possession or otherwise of the faculty of speech is the best distinction of which the nature of the case adm.its. The majoi'ity of imbeciles exhibit intellectual as well as moral deficiency. They cannot acquire or retain knowledge ; they cannot understand or appreciate the customs of society and laws human and divine; they cannot bring their emotions and passions under control, as men of sound mind are able to do. But there is a small exceptional class which exhibits intellectual deficiency without seriously offending against morality, and a larger class which combines the highest intel- lectual endowments with utter incapacity in the conduct of life. There is, therefore, an intellectual, a moral, and a general imbecility, as there is an intellectual, moral, and general mania. The form of imbecility which is most common and most important in a medico-legal point of view is that which aflfects the intellect, the morals, and the prudential conduct of life. Persons who exhibit this threefold deficiency profit by education, so as to foi-m and express simple ideas ; to read, write, and count ; and to become musicians, draughtsmen, or mechanics. They may even attain to proficiency in some one branch of knowledge, or some one accomplishment. But they do not profit by the opportunities afforded them in the same degree as their neighbours. They present great varieties of character. Some are fickle and changeable, and incapable of fixing their attention ; others are methodical and persevering. Some of them are found fit only for the coarsest and rudest labours, while others are equal, with the assistance and guidance of otbei-s, to the conduct of business and IMBECILITY. 163 tlie management of pi-operty. Others know the value of money, and can give infoiination on the matters with which they are conversant, but they are unequal to emergencies, and unable to sustain close conver- sation or argument. They are thoughtless, improvident, uneasy, and restless, and generally incapable of strong and steady attachment. Imbeciles are very common among the lower orders of society. They are found following occupations requiring little sense or skill. Their neighbours look upon them as weak and singular persons, and tease and torment them accordingly. Many of them become lazy, drunken, and dissipated; and some, under slight temptation, and very in- iidequate motives, break out into fits of ungovernable passion, and commit acts of theft, arson, rape, or murder. " They steal adroitly, and hence are considered as very intelligent : they recommence their offences the moment they are released from confinement, and thus are believed to be obstinately perverse." " They have no idea, or a very imperfect one, of society, laws, morality, courts, and trials ; and though they may have the idea of property, they have no conception of the con- sequences of theft. They may have been taught to refrain from injuring others, but they are ignorant of what would be done to them if guilty of incendiarism or murder." " Their conduct is actuated solely by the fear of punishment, when capable of experiencing that sentiment, and by their own desires. Others have some notions of property, but neither a sense of morality, nor a fear of punishment furnishes motives sufiiciently powerful to prevent them from stealing." Georget, from whose work, ' Sur la Folic,' these passages are quoted, says that " these beings of limited capacity furnish to the courts of justice, to prisons and scaffolds, moi'e subjects than is generally supposed." Imbecility, as has been already pointed out, is not necessarily of this general character, displaying itself at the same time in the intellect, morals, and conduct. It is sometimes partial, affecting only or chiefly either the intellectual or the moral character. There may be, on the one hand, an inability to acquire and apply knowledge in persons who have a due sense of right, act with integrity, and perform every social duty ; and, on the other hand, an unusual power of acquiring know- ledge, with judgment, fancy, and refined taste, but combined with feebleness of purpose, want of self control, inaptitude for business, disregard of duty, and want of common honesty. Such persons are known in society as weak, soft, easy, good-natured, well-meaning, good sort of people, and if possessed of brilliant talents, as having every sense but common sense. They are too easy to be just ; too thought- less to be honest. They have an instinctive horror of business, an aversion to their regular occupations, and a distaste for everything that wears the shape of a duty. They are utterly ignorant of the value of money, and the last use they make of it is to pay their debts. Each man among them has his own favourite form of extravagance, and his own mode of ruining himself. One calls an architect to his assistance ; another an upholsterer ; a third collects useful things which he never 164 UNSOUNDNESS OF MIND. uses, or displays a curious taste in worthless trifles. They aie always forming acquaintances with unworthy persons, who find it worth their while to know and to flatter them. With all their easiness of dis- position they have much warmth of temper and strength of passion. They are bad children, husbands, and fathers, because in these relations of life they have duties to perform. Throughout life they are weak, wavering, fickle, and self-willed, as children ; the soun^e of constant anxiety and misery to their families ; the prey of designing knaves ; the expected inmates of gaols, workhouses, and lunatic asylums. These moral imbeciles remain at large, because the intellect being unaffected, they have no distinct delusions, and there is nothing appa- rently to prevent them fiom becoming, at any moment, useful members of society. As weakness of intellect is a necessary ingredient in the legal idea of imbecility, the attempt to prove such persons of unsound mind, in a court of law, must necessarily fail. That absence of moral sense, and corresponding want of self-control which is the essence of their mental malady, is to be proved only by the history of their daily life. Imbeciles are sometimes as much under the dominion of childish fancies as maniacs are of delusions. A few years since a commission of lunacy was granted in the case of a young gentleman, aged 20, who was the slave of a childish fancy for windmills, with an aversion equally strong to watermills. Having been jjlaced under control in a place where there were no windmills, he cut the calves of a child's legs through to the bone, and stated that he should have taken away its life, that he might be tried for his act, and removed from a place where there were no windmills. He had always been violent when thwarted in his fancy, had threatened his keeper and members of his family, and had more than once made preparations for committing murder. ^In this instance, childishness of fancy, insufficiency of motive, absurdity of act, and ignorance of legal consequences were strikingly combined. Legal Relations of Imbecility. — In respect to this foi-m of mental unsoundness, two distinct orders of questions may arise — questions of competency, and questions of responsibility. • The competency of imbeciles to form contracts, and the validity of them when formed, has, in more than one instance, engaged the atten- tion of our courts of law. Persons of weak mind have been brought by improper influence to ally themselves in marriage, and the validity of such marriages has been successfully disputed, as in the case of Portsmouth v. Portsmouth, in which, as in other instances that might be cited, the proof of imbecility was not drawn from a few isolated facts, but from an investigation of the whole life, conduct, and cha- racter of the party. The competency of imbeciles to manage themselves and their affairs is often called in question. As the conduct of life is partly dependent on a knowledge of such simple mattei-s as the value of money, and IMBECILITY. 165 partly on judgment and discretion, inquiries of this class sometimes assume a very simple, and at other times a very complicated shape. la rare instances men have been pronounced incapable of managing their affairs, on the ground not so much of general weakness of in- tellect, as of a defective knowledge of numbers and of the value of money. Two such cases are related by Dr. Abercrorabie, in one of which the most prominent character was a " total inability to perform the most simple process of arithmetic," and in the other *' a total want of the power of tracing relations both as to time and numbers." In the face of evidence showing that they had made much progress in their education, both were pronounced incapable of managing their affairs. In a case of imbecility on which the author was called to give evi- dence, the patient did not know how many pence there were in sixpence or a shilling, or how many shillings in a sovereign ; could not perform the most ordinary operation of arithmetic ; was ignorant of the date, the month, and the year ; did not know the name of the reigning monarch ; could not recognize persons whom he had seen and conversed with only four days previously. His attention was aroused with the utmost difficulty, and could not be fixed to any one subject. His look was vacant, his dress peculiar, his gait awkward, his motions grotesque, his speech slow and hesitating. He used the same words and expressions again and again, repeated imperfectly the tasks and prayers of his childhood, and imitated the contortions of persons, like himself, subject to fits. Such a case could present no difticulty either to the medical witness or to the jury. The more complicated and difficult class of cases arise in respect of persons who though they display many marks of imbecility, in childish ways, eccentric habits, violent passions, and cruel dispositions, are yet able to perform the simple operations of arithmetic, know the value of money, and can comprehend such statements and suggestions with respect to their affaii's as may be submitted to them. In some of these cases, a successful appeal has been made to the efficient manner in which the party has actually conducted his own affairs. The proof of imbecility, combined with undue influence, has, in numerous instances, been held to invalidate a will ; but, in the absence of such influence, all that is required to establish the wills of people of weak understanding is, that they should have been capable of compre- hending their nature and effect. The question of responsibility for crimes, such as arson and murder, can also only be answered by an appeal to all the circumstances of the act, the motives by which it was instigated, and the whole life and character of the accused. This subject of responsibility in criminal cases will be more fully considered when all the forms of unsound mind have been passed in review. Several interesting and instructive cases of imbeciles concerning whom the two questions of competency and responsibility have been raised. It'G UNSOUNDNESS OF MIND. are given in detail, and made the subject of judicious commentary in Dr. Kay's * Treatise on the Medical Jurisprudence of Insanity.' Cretinism. — In many parts of the continent of Europe, especially in valleys lying among hills, but occasionally in unhealthy rural and urban districts in every part of the world, a disease prevails which combines the extreme of bodily deformity and degeneracy with deficiency of in- tellect. In Switzerland and Savoy persons so afflicted are called cretins, and in France cagots. The morbid feature by which they are chiefly distinguished is the enlargement of the throat, known as goitre or bron- chocele ; but to this several bodily defects and deformities are super- added. The stature is dwarfed, the belly large, the legs small, the head conical, the arch of the palate high and narrow, the teeth irregular, the mouth large, the lips thick, the complexion sallow, the voice harsh and shrill, the speech thick and indistinct, the eyes squinting, the gait feeble and unsteady, the sexual power weak, or wanting. The best authorities agree in representing this physical degeneracy, with the coexisting mental deficiency, as commonly dating from a period subsequent to birth. About the fifth or sixth month, the healthy bodily development seems to be checked. The child looks unhealthy and seems weak ; the head is large, and the bones widely separated ; the belly swells and the limbs shrink ; teething goes on very slowly, and the child cannot stand or speak till its fifth or sixth year. Some cases are complicated with spinal distortion, some with hydro- cephalus. In rare instances the physical and mental deficiency dates from birth. It is usual to divide the victims of this singular affection into three classes — cretins, semi-cretins, and the cretinous, or cretins of the third degree. The first class answer to the description of idiocy already given, with the addition of the peculiar deformity of the throat. Their life is automatic; they have no trace of intelligence; their senses are dull, or wholly wanting ; they are unable to speak ; their time is spent in basking in the sun or sitting by the fire ; and nothing but the most urgent calls of nature rouses their attention. They do not possess the power of reproduction. The next class, or semi-cretins, show a higher degree of intelligence. They may be taught to read and to repeat prayers, but without under- standing what they leam ; they have no idea of numbers ; they note what passes aroimd them, and use language to express their wants ; they remember common events, understand what is said to them, and speak intelligibly on common subjects. Cretins of the third degree show glimpses of a higher nature, and are capable of attaining a certain degree of proficiency in mechanical em- ployments and contrivances, in drawing, painting, and music; but arithmetic is a very rare acquirement. They are said to be acutely alive to their own interest, extremely litigious, unable to manage themselves or their affairs, but obstinate and unwilling to be advised. Cretins of the second and third degrees, if remeved from the place of DEMENTIA. 167 their birth and placed under judicious superintendence early in life, are cjipable of considerable improvement both of body and mind, and may be made useful members of society. DEMENTIA. This form of mental unsoundness is to be carefully distinguished from the two forms of amentia just described. In idiocy the deficiency is congenital ; in imbecility it shows itself in early life ; in dementia, on the contrary, it supervenes slowly or suddenly in a mind already fully developed. Dementia differs from mania, on the other hand, inasmuch as the one arises out of the exhaustion and torpor of the faculties, the other from their iindue excitement. The state of the mind in dementia is best described by the word incoherence. There is also a form of mania equally well described by the same word ; but the incoherence of dementia is marked by languor, that of mania by excitement. It must, however, be understood that patients suffering from dementia are liable to maniacal paroxysms, and maniacs to remissions of comparatively tranquil incoherence. Dementia is divided into acute and chronic, of which the first form is rare, and consists in a condition of profound melancholy or stupor ; tlie second of very common occurrence, and characterized by inco- herence. There are also degrees or stages of dementia, which Prichard indi- cated by the words forgetfulne.ss, irrationality, incomprehension, and inappetency. A patient suffering from dementia, and passing from bad to worse, would first exhibit want of memory, then loss of reasoning power, then inability to compi'ehend, and, lastly, an abolition of the common instincts and of volition. Dementia may occur at any period of life after the development of the mental faculties — in childhood, manhood, or old age. When it occurs in aged persons it is known as senile dementia. The chaKicters of dementia differ with its cause and mode of com- mencement. That form of it which arises from sudden mental shocks often presents a distinct and very peculiar feature. — The mind is, as it were, arrested and fixed for the remainder of life in sad abstraction on the one event which had occasioned it. In other instances, the shock destroys the power of the mind, and reduces it to a state of imbecility or idiocy. During the earthquake panic of 1843, the author had an opportunity of seeing a case of dementia in a lad of twelve years of age, brought on by the conversation of a knot of Irishmen in the dusk of the evening, concerning the expected visitation. The poor boy seemed deprived of all his faculties, was dull and listless, and answered every inquiry by a vacant smile. He occasionally had an access of terror and excitement, but soon relapsed into his state of stupor. The prolonged action of apprehension or grief is another cause of dementia. Dementia also follows upon severe attacks of fever, and 168 UNSOUNDNESS OF MIND. upon mania, melancholia, apoplexy, paralysis, or repeated attacks of epilepsy. In all these cases it may depend on softening or other chronic disease of the brain. Senile Dementia, or that which is jncidental to persons in advanced age, is the most simple and well-marked form of that variety of de- mentia which arises from causes acting slowly and gradually. The first symptom of approaching senile dementia is loss of the memory of recent events, with dulness of perception and apprehension, and an inability to fix the attention, or to follow any train of thought. The things which were heard five minutes since, are forgotten, and the same question is repeated over and over again. Hence, the transaction of business requii-ing sustained attention becomes impossible. The power of attention, and the control of the will over the thoughts, becoming more and more enfeebled, the reasoning powers suffer ; for scarcely are the premisses laid down before they are forgotten, so that the act of comparison by which the conclusion is arrived at cannot be performed. Hence, after pursuing the same topic of conversation through part of a sentence, some accidental suggestion turns the ideas aside. Persons so aiFected know their attendants and recognize their friends, but they seldom display signs of emotion on seeing them ; and they can still employ themselves mechanically, — men in writing, and women in knitting and sewing. The next phase of the malady is one of complete incomprehension. Memory, reason, and the power of at- tention are entirely lost ; but the muscular force remains intact, and displays itself in perpetual activity, in jumping or running to and fro, or walking round in a circle, or rocking backwards and forwards in a chair, dancing, singing, and shouting, or in talking or muttering in- cessantly. Many, however, sit silent and tranquil, or with a vacant unmeaning stare, for weeks, months, or even years. A few remain crouched in one uneasy posture, or they stand erect with the neck rigidly fixed at right angles to the body. In the last stage of all, even the animal instincts are lost ; there is neither sensation, nor memory, nor thought, nor reason, but bare physical existence ; with occasionally, at distant intervals, a short resuscitation of some of the mental powers. Paralysis of the limbs, more or less extensive and complete, is also a common occurrence in this advanced stage of the malady. Legal Relations of Dementia. — The questions most commonly raised respecting this form of unsoundness of mind relate to the validity of wills made or altered by aged persons £tlleged to be suffering from senile dementia. The inquiry is generally one of considerable difficulty ; inasmuch as patients suffering from senile dementia vary greatly from day to day, and present themselves to different pei-sons in different lights. Accordingly there is room for very conflicting testimony, and wide divergences of opinion, both among unskilled and skilled wit- nesses; and the legal decision ultimately turns much more on the character of the will itself and its consonancy, or otherwise, with the MANIA. 169 known intentions and views of the testator at an earlier period of his life, and with the natural feelings of persons of sound intellect, than on the medical or other evidence respecting his mental condition. MANIA. This term includes all those forms of unsoundness of mind which are characterized by undue excitement of the faculties. It differs therefore in a marked manner from those already described, both in its legal relations, and in the tests by which its existence is ascer- tained. There is no legal term in common use which properly charac- terizes this state ; and one of its most important forms, moral insanity, is as yet unrecognized by the law. The only legal term employed in a sense analogous to that of mania is lunacy, which, as has been remarked, is objectionable from being founded on a variable feature of the disease. Mania is divided in the table at p. 152 into three classes: General, Intellectual, and Moral ; and each of these latter into two subdivisions — General and Partial. General Mania. — There is a form of mania which affects both the intellect and the passions, and throws the whole mind into a state of mingled excitement and confusion. It is the counterpart of the inco- herent stage of dementia, and the form which, in some cases, mania assumes from the very first. It would be correctly designated by the phrase " raging incoherence." There is another form of mania which is apt to be confounded with the foregoing variety, on the one hand, and with monomania on the other, but which, when carefully examined, will be found to be a general unsoundness, accompanied with undue excitement of the mind, the predominant feeUng or passion merely taking the lead in the unsound, as it had previously done in the sound mind. Both of these forms will be treated under the general term, Mania. Mania, under whatever form it may appear, except when it is the immediate consequence of injuries, moral shocks, intoxication, poison- ing, or acute disease, is preceded by important bodily and mental changes. The period during which these changes are taking place is termed the period of incubation, which sometimes embraces a pei'iod of fifteen to twenty years. It is described by Georget in terms of which the following is an abbreviation : — Sometimes the cause acts strongly and rapidly; at other times, slowly and with less force. In the first case, madness breaks out at the end of some hours or days after a state of anxiety and uneasiness, with headache, sleeplessness, excitement, or depression. The patient begins to babble, cry, and sing, becomes wild and agitated, and has the appearance of a person in a state of intoxication. In the second case, the mind is affected gradually and often very slowly. The patient is generally conscious of some disorder in his intellectual faculties ; he is 170 UNSOUNDNESS OF MIND. beset by new and odd notions, and bj' unusual inclinations ; he feels himself changing in his affections; but, at the same time, he preserves a consciousness of his condition, is vexed at it, and tries to conceal it ; he continues his occupations as much as he can ; and like a man in the first stage of intoxication, he makes every effort to appear reasonable. Meantime his health gives way. He either sleeps less or not at all ; his appetite is impaired or lost ; he suffers from indigestion and consti- pation ; he grows thin, and the features alter. (In females the monthly discharge becomes irregular and scanty, and at last is altogether sus- pended.) At the same time a great change takes place in the tastes, habits, affections, and character of the patient, and in his aptitude for business ; if he was gay, communicative, and social, he becomes sad, morose, and averse to society; if he was open and candid, he becomes suspicious and jealous ; if he was moderate in his political and religious opinions, he passes to an extreme exaggeration in both ; if he was affec- tionately attached to wife, children, or relations, he regards them with indifl^erence or dislike ; tears and laughter succeed each other without apparent cause ; if he was orderly and economical, he becomes confused and prodigal ; if he has been coiTect in his conversation, he indulges in violent and obscene language ; if he had long abstained from the plea- sures of love, he becomes the victim of insatiable desires, and either seeks to associate with the other sex, or has recourse to disgraceful practices. If this is the first attack, the persons by whom he is surrounded do not suspect the nature of the ailment which torments him ; they put questions to him which lead to no result, except that of fatiguing and giving him pain ; or they indulge in offensive insinuations, and charge him with frivolous accusations ; and when, at length, he breaks out into furious mania, the attack is attributed to some slight contradiction or some cause equally inadequate to produce it. When the period of incubation has passed, and the disease is fully established, the mental and physical phenomena undergo a change. The disorder of the cerebral functions assumes a more positive cha- racter, the patient believes in the reality of his delusions, and instead of concealing his thoughts, openly and strenuously avows them, except when induced by powerful motives to pursue a contrary course. When thwarted and opposed he makes use of the most violent and insulting language, and often gives utterance to the most obscene expressions. In many cases, too, his violence does not spend itself in words, but he tears his clothes and bedding to pieces, and inflicts bodily injury on himself and those about him. The physical derangement displays itself in febrile excitement, an accelerated pulse, and a wild and sparkling eye, pain, weight and giddiness in the head, ringing in the ears, and restlessness and sleeplessness. The patient is also singularly insensible to cold and heat, and he either abstains from food and drink for long in* tervals of time, or eats voraciously. The muscular power is inordinately developed, and the patient sustains for a long time, without sleep, a INTELLECTUAL MANIA, GENERAL AND PARTIAL. 171 succession of efforts which would soon utterly exhaust a healthy pei'son. The habits of the patient are often most disgusting and offensive. General Intellectual Mania. — The opinion is gaining ground that mania is in all cases primarily an emotional disease, and that the alfection of the intellect is only secondary. But there is certainly a class of cases in which the disease appears to be almost limited to the intellectual faculties, which are in a highly excited state, while the moral faculties are little if at all affected. But it would probably be more correct to say that, in certain cases, some strong emotion or passion, such as pride, vanity, or ambition, displays itself chiefly by its effect upon the intellect. Thus Dr. Keid, in his work on Insanity, tells us of a vain young medical student, who, in the expectation of realizing a fortune by attaining academical honours, entered himself at Cambridge, and so injured his health by fruitless application to study, as at length to fall into a state of decided de- rangement. This young man stated that he was the Farnese Her- cules; that he had written Dr. Clarke's Travels in Russia; that he had composed the ^neid of Virgil ; had painted one of the master- pieces of Kaffaelle ; and that he knew everything. Dr. Henry Johnson, in his work on the arrangement and nomen- clature of Mental Disorders, also gives the highly characteristic letter of an ambitious patient who contrived to confer upon himself the some- what incongruous titles of champion and king of England, and heir presumptive to the crown, and at the same time to monopolize all the principal offices of state. A highly instructive autobiography of a gentleman who had re- covered from an attack of mania, shows how general was the dis- turbance of the whole intellectual and moral being, though the pre- dominant emotion was of a religious character, and it would have been quite possible to describe the case as one of religious monomania. General intellectual mania is, therefore, in very many cases, to be regarded as the violent disturbance of all the intellectual faculties brought about by the over-excitement of some leading emotion or passion. Partial Intellectual Mania. — This was formerly called melancholia, from the mistaken notion that such partial affections of the intellect are always of a gloomy character. Esquirol showed that this view of the case was incorrect, inasmuch as the ideas of such persons are not always gloomy, but, on the contrary, oftentimes extremely gay and pleasant; and he substituted the term monomania, which is now generally received. The most simple form of this disorder is that in which the patient takes up some single notion opposed to common sense, and pei'sonal experience ; such as, that he is secretary to the moon, the Crystal Palace, a grain of wheat, a goose-pie, a pitcher of oil, a wolf, a dog, or a cat. In many cases, this single delusive idea relates to, or is occasioned 172 UNSOUNDNESS OF MIND. by, some bodily sensation or disease, which the monomaniac, like the dreamer, associates with imaginary accompaniments, and interprets by the aid of his delusion. Thus, Esquirol tells us of a woman suffering from hydatids in the womb, who insisted that she was pregnant with the devil ; of another, whQ having adhesions of the intestines from chronic peritonitis, imagined that a regiment of soldiers lay concealed in her belly, and that she could feel them struggling and fighting with each other ; and of a third, who, sufl'eiing from the same morbid con- dition, believed that the apostles and evangelists had taken up their abode in her bowels, and were occasionally visited by the pope and the patriarchs of the Old Testament. But such delusions as these, though perhaps originally founded upon real sensations, may continue after the sensations themselves have passed away, as is proved by the cures that have been effected by a very laudable species of deception. Thus, a patient, after thinking himself cured of a serpent in his bowels by means of a pretended surgical operation, suddenly took up the idea, that the creature had left its ova behind, ready to be hatched into a brood of young ones ; but was reassured by the dexterous reply, that the snake was a male. It must not be supposed that such cases of partial intellectual mania comprise all the cases designated as monomania. In most instances the affection of the mind doubtless goes beyond a single insane idea, and influences more or less extensively the thoughts and the conduct, being marked by other intellectual and moral inconsistencies: and there is reason to believe, that many cases of so-called monomania are examples of general mania, characterized by the immoderate activity of some one faculty. Moral Mania. — It was Pinel who first directed the attention of the profession to moral insanity. Previous to his time, insanity was generally considered as either exclusively, or chiefly, a malady of the reasoning faculties. Participating in the common belief of the suffi- ciency of a few faculties to explain all the phenomena of the sound and unsound mind, and doubtless influenced by the prevalent metaphysical doctrines of his time, he found, to his great sui-prise, that there were at the Bicetre many maniacs " who betrayed no lesion whatever of the understanding, but were under the dominion of instinctive and ab- stract fury, as if the affective faculties alone had sustained injury.'' He called this fonn of mental disorder manie sans delire. Since his time the reality and great importance of this distinction between intellectual and moral mania have been recognized by practical ob- servers, amongst whom are to be found the well-known names of Esquirol, Georget, Gall, Rush, Keil, Heinroth, Hoffbauer, Cox, Andrew Combe, Abercrombie, ConoUy, Pri^chard, and Ray. Pn\ chard, who has treated this subject with great ability, and has clearly made out that moral generally precedes intellectual insanity, defines moral mania as " consisting in a morbid perversion of the natural feel- ings, affections, inclinations, temper, habits, and moral dispositions, GENERAL MORAL MANIA. 173 Without any notable lesion of the intellect, or knowing and reasoning faculties, and particularly without any maniacal hallucination." Moral mania, like intellectual mania, admits of being distinguished as general and partial. General Moral Mania. — Pn\chard observes that there are many individuals living at large in society, who are reputed persons of a singular, waywai'd, and eccentric character. An attentive observer will often recognize something remarkable in their manners and habits, which may lead him to entertain doubts as to their sanity ; and on inquiry his suspicions are often strengthened by finding that an hereditary tendency to madness has existed in the family, that several of the relations have laboured under other diseases of the brain, or that the individual himself, in a former pei'iod of his life, has had a decided attack of madness. His temper and disposition are found to have undergone a change ; to be not what they were previously to a certain time ; he has become an altered man, and the difference has perhaps been noted from the period when he sustained some reverse of fortune, which deeply affected him, or the loss of some beloved relative, or some severe shock to his constitution, — some febrile or inflammatory dis- order affecting the brain, a slight attack of paralysis, or a fit of epilepsy. In some cases, the alteration in temper and habits has been gradual and imperceptible, and seems to have consisted only in an exaltation or in- crease of peculiarities which were always more or less natural and habitual. Persons labouring under this disorder are capable of reason- ing, or supporting an argument, upon any subject within their sphere of knowledge, and they often display great ingenuity in giving reasons for the eccentricities of their conduct, and in accounting for and justify- ing their existing state of moral feeling. In one sense, indeed, their intellectual faculties may be termed unsound ; they think and act under the influence of strongly-excited feelings, and persons accounted sane are under such circumstances proverbially liable to error both in judg- ment and conduct. Hoffbauer, who has written very ably on the subject of insanity, re- cognizes this form of mental unsoundness. *' It is clear," he says, " that mania may exist uncomplicated with' mental delusion ; it is, in fact, only a kind of mental exaltation {toll- heit), a state in which the reason has lost its empire over the passions and the actions by which they are manifested, to such a degree, that the individual can neither repi-ess the former, nor abstain from the lattex". It does not follow that he may not be in possession of his senses, and even of his usual intelligence, since, in order to resist the impulses of the passions, it is not sufficient that the reason should impart its counsels, — we must have the necessary power to obey them. The maniac may judge correctly of his actions without being in a con- dition to repress his passions, and to abstain from the acts of violence to which they impel him." He subsequently observes, that when mania proceeds from inordinate passions, " its more immediate cause 174: UNSOUNDNESS OF MIND. lies in the physical temperament, or in certain moral affections which induce frequent occasions of anger. In every other respect, the maniac may be master of his propensities, and the actions to which they lead ; he may judge and act rationally. He is irrational only in his paroxysms of fury, and then his errors of judgment are rather the effect than the cause of his furious transports." This form of mental unsoundness is illustrated in the works of Pi'r^chard and Pay, by a large number of cases, which may be con- sulted with advantage. Of these, the most remarkable is that of Frederick William of Prussia, father of Frederick the Great, a drink- ing and smoking hypochondriac, and the strange, waywai-d, and cruel tyrant of his family and household. His religious austerities, his disgusting and brutal behaviour to his children, his unfounded hatred of his own son, and repeated attempts upon his life, his solitary attempt upon his own life, his course of steady and unswerving per- secution of the innocent objects of his suspicion and dislike, without any delusion beyond that which might fairly be regarded as the offspring of his hate — present a striking picture of general moral mania. Partial Moral Mania. — This consists in an exorbitant activity of some one passion or propensity, and its predominance or complete mastery over every other. The persons thus affected are generally perfectly conscious of their condition, and they either evince the utmost horror at the enormity of the conduct to which their ruling passion would impel them, and with difficulty restrain themselves, or they give way, as if in desperation, to the impulse which urges them on. There is not one of the stronger impulses of our nature that may not be thus placed, by morbid excitement, beyond the restraint of reason and conscience. The following varieties are now generally recognized, and described under distinct names : — Kleptomania, Eroto- mania, Pyroraania, Dipsomania, Suicidal Mania, Homicidal Mania. In addition to these forms of partial moral mania, which are of special interest to the public and the legislature, there are many other distinct vaiieties, some marked by extreme depression, and others by great excitement, which have been classed under the two heads of Melancholia and Exaltation, of which the first comprises the three species, hypo- chondriasis, nostalgia, and religious despair ; and the second excessive pride, vanity, or ambition. Cleptomania, or propensity to theft. — This form of partial moral mania is of very common occurrence in persons of both sexes, placed by their wealth beyond the reach of vulgar temptation. It is more common in women than in men. A propensity to theft is also a common feature of imbecility and of mania, and has been known to accompany maniacal paroxysms. Pri)|chard mentions the curious case of a lunatic who would never eat his food unless he had pre- viously stolen it. SUICIDAL MONOMANIA. 175 Erotomania, or amorous madness. — This disease is otherwise known as Satyriasis when it attacks men, and Nymphomania when it occurs in women. It sometimes attacks virtuous females, who view their excited passions with horror and remorse. Pyromania, or propensity to incendiarism. — This propensity, in common with Kleptomania, is more common in women than in men. It occurs most frequently in young women subject to menstrual sup- pression or disturbance, and in imbeciles of the other sex. Dipsomania. — A propensity to excessive indulgence in spirituous liquors is a well-recognized form of unsoundness of mind. In some persons the desire for drink is continuous ; in others intermittent. In some the desire is but part of a more general unsoundness ; in others it is the true source of all the manifestations of unsoundness which the patient makes. In other words, he is perfectly rational when not under the influence of drink. Suicidal Monomania. — Much difference of opinion has existed as to the real state of mind of self-murderers. The fact of suicide having been generally practised and sanctioned by philosophers and lawgivers of past times, and of its still being in common use in nations which have attained in many respects a high civilization, such as China and Japan, has led some to the belief that it is not always the result of an insane impulse. The calm and deliberate manner in which the crime is often perpetrated, and the apparent soundness of the reasons alleged in its favour, have been somewhat strangely used as arguments against the opinion of those who attribute suicide in all cases to insanity. A better reason for believing it to be, occasionally at least, altogether in- dependent of insanity is, that in France two persons often combine for the purpose of self-destruction ; such union of purpose being extremely rare in the case of the insane. The argument drawn from national usage in ancient and modern times cannot be allowed much weight, for who would hesitate to cha- racterize an English widow who should burn herself on the death of her husband, as insane? and yet such self-sacrifice was until recently both a virtue and a custom in India. Some savage nations, again, eat human flesh ; but in a case of infanticide which occurred in France, the fact that the mother cooked a portion of her child, and ate of it, and then offered the dish to her husband, was justly regarded as a strong evidence of insanity. A careful consideration of recorded cases of suicide cannot but lead to the conclusion, that a considerable number are the result of insane impulse ; and this conclusion is strengthened by the frequent attempts at self-destruction made by the acknowledgedly insane. The extraor- dinary modes of death sometimes selected might also be urged as an additional argument in favour of the insane origin of suicide. It may be added, that some of our highest authorities, as Fodere and Esquirol, have strongly maintained the necessary dependence of suicide on in- sanity. 176 UNSOUNDNESS OF MIND. Homicidal Mania. — The most distinguished authors, botli at lionie and abroad, have recoc;nized this form of mental unsoundness, as having an existence independent of delusion. The cases on record are now very numerous, and comprise instances of successful resistance to the impulse in some instances, of voluntary submission to restraint in others, and examples of failure in a third class. Women seem to have been more frequently than men the victims of this propensity to destroy, and sometimes this excited feeling has led to the commission of infanticide (see p. 111). Females suffering from grief, or anxiety, from habitual discharges, at the menstrual period, at the change of life, and soon after delivery, are thrown into a peculiar nervous state, known as mimosis inqnieta, which is sometimes accom- panied by a strong impulse to crime, with an overwhelming fear of giving way to it. Cases of this kind frequently present themselves among the out-patients of our hospitals. Melancholia. — There are, as has just been stated, three principal forms of melancholia, all of which are characterized by profound sadness. The first, hi/pochondriasis, consists in a melancholy and desponding view of the condition of the body and of the health, often, but not always, based upon uneasy bodily sensations and disorders of the organs of digestion: the second, nostalgia, consists in an intense longing for country and home in those who are exiled : the third, religious despair. Exaltation. — This is a state of mind the opposite of melancholia, which prevails in those who exult in the belief that they are possessed of great personal attrjiction, great power, great dignity, great inven- tive faculties, or great projects of benevolence. It would also be quite possible to select cases from all large col- lections of insane persons, which would warrant the use of a larger vocabulary of terms — cases, for instance, in which a lying or begging propensity is quite as clearly marked as a thieving propensity in those designated as Cleptomaniacs. Nor is it possible to omit the remarkable cases of lycanthrophy which are on record, and one of which Cthat of the soldier Bertrand) has, within a few years of this time, occurred in France. In this instance, the violation of the grave was an intermittent insane passion, which no sense of personal danger was allowed to disappoint. Of Mania with Lucid intervals. -^'Mdima., in a considerable number of cases, assumes a recurrent or intermittent form, the patient in the interval being in his right mind. The proportion which such cases bear to those of complete recovery has been variously stated at from one in six to one in ten. The interval is various. Esquirol has seen cases assume the quotidian, tertian, and quartan type ; or the interval has been that of a month, or it has recurred with the same season of the year. More frequently the attacks occur at uncertain intervals, and are of uncertain duration. This recurrent mania, with intervals of complete sanity, must not be confounded with those periods of CHARACTERS OF AMENTIA AND DEMENTIA. 177 comparative tranquillity which, like lulls in a storm, occur in most cases of mania. With regard to such intervals of comparative repose, Haslam remarks that, " as a constant observer of this disease for more than twenty-five years, he cannot affirm that the lunatics, with whom he had daily intercourse, have manifested alternations of in- sanity and reason. They may at intervals become more tranquil, and less disposed to obtrude their distempered fancies into notice. For a time their minds may be less active, and the succession of their thoughts consequently more deliberate ; they may endeavour to effect some desirable purpose, and artfully c mceal their real opinions ; but they have not abandoned or renounced their distempered notions." The legal relations of mania with lucid intervals are important. The law generally views civil acts done in lucid intervals as if they were performed by a person in a permanently sound state of mind ; it admits the validity of wills made during such intervals, and has on more than one occasion admitted the I'easonableness of the will as proof of a lucid interval. With regard to criminal acts, it makes a reasonable distinction ; for it justly regards the condition of unsound- ness as one readily reproduced by provocation or excitement. The legal relations of the other forms of mania will be considered in the following division. 4. OF SOME OF THE MORE IMPORTANT CHARACTERS OF THE UN- SOUND MIND, AND OF THE LEGAL AND MEDICAL TESTS OF THAT UNSOUNDNESS. A knowledge of the individual characters of mental unsoundness is of the first importance both to the lawyer and to the ])hysician. Without a resume' of its characteristics, a mere description of its several forms would present but an imperfect view of the subject. It is proposed, therefore, to establish, by appeal to facts, some, of the more remarkable phenomena of mental unsoundness, as a preliminary to the discussion of the chief legal questions which arise out of that state, and to prescribe, for the guidance of the medical witness, such rules as these phenomena shall be found to suggest for recognizing it, and for distinguishing it from its counterfeit. Of the Characters of Unsoundness of Mind from Defective Development or Diminished Activity of the Faculties. There is a simplicity about this division of the subject which does not belong to the other, and the principal characters are more easily deduced from the foregoing descriptions. The law, in reference to this form of unsoundness, moreovei', is more simple and more in ac- cordance with medical experience ; and its decisions have been more uniform. 178 UNSOUNDNESS OF MIND. The appearance of the idiot or imbecile is in itself almost decisive, and scarcely requires confirmation from an actual inquiry into his mental condition. Difficulty of arousing and fixing the attention ; slowness and weakness of comprehension ; forgetfulness of recent oc- currences ; ignorance of social relations ; unconsciousness of familiar things, even of such as immediately concern a man's self, as his age, the place in which he lives, and the mode in which he passes his time, the year, the month, and date of the month ; ignorance of those public persons and events which are the most frequent topics of conversation, and most familiar to those who take an interest in the common affairs of life, as the name of the reigning monarch, of the prime minister, &c. ; a scanty knowledge of arithmetic and of the value of money ; an imperfect knowledge of right and wrong, and of the state of the law in regard to the most common and familiar crimes ; — may be mentioned among the characters of the several forms of un- soundness from defective development. In ordinary and extreme cases of imbecility there can be no diffi- culty in forming a decision as to the competency of the iq^dividual to take care of himself and his affairs, to form contracts, to devise i)ro- perty, &c. ; but where the imbecility exists in a less degree, the question is by no means of this simple nature, and cases have occurred in which there has been room for much difference of opinion. In this class of cases it generally happens that the individual in question has for some part of his life been at liberty, and entrusted with the management of his affairs. Hence an invaluable tost is provided in a comparison of his existing with his former state of mind. This simple and obvious test seems to have been strangely overlooked by medical men, till the interesting case of Mr. Edward Davies gave Dr. Gooch the opportunity of pointing it out, and insisting upon its importance. (See ' Quarterly Review,' 1830, and the fiist edition of this work.) The tests of capacity usually recommended in the case of imbeciles are obviously insufficient to determine whether or not a man is (^- pable of managing his own property. The arithmetical test, on which authors have laid so much stress, is merely a test of knowledge, not of power. A man may be the best accountant in the world, but he may labour under a moral imbecility, and have so mean a sense of right, so childish a fancy, and so weak a will, that from infancy to age he may yield to every impulse, and gratify every whim without once counting the cost. In a case that lately came under the author's notice, the individual owed pence as a child, and pounds as a boy, and added debt to debt with each year that passed over his head, till at length a severe disappointment brought on a distinct attack of mania, of which a benevolent but extravagant mission, violent outbursts of passion, and fierce hatreds, arrangements to spend a year's income in a week, and the unfounded expectation of an immense fortune on the morrow, were constituent parts. He became the inmate of an asylum. CHARACTERS OF MANIA. 179 with delusions enough to furnish a dozen madmen, settling down at last into the conviction that he was the Saviour of mankind, in which conviction he died. In this case, there was the cultivated and refined intellect of a man with more than the weakness of a child ; but no test could have served to prove him incapable of managing himself and his affiiirs, save only the history of his life. The criminal acts of persons of weak intellect are as strongly marked by folly as their daily words and actions. They have no other characters, and consequently we have no better test. In the case of imbeciles, as in that of maniacs, the law lays down the test of a knowledge of right and wrong. This is as insufficient a test in criminal, as the arithmetical test in civil cases. It is a test of know- ledge, and not of power ; and the knowledge of right, and the power to act right, are as distinct as science and art. This subject will be pre- sently examined more at length. Of the Characters of Unsoundness of Mind from Excessive Activity of the Faculties. In tracing some of the more prominent characters of this division, or, in other words, of mania, it is proposed to use the term in its most extended sense as applied to those cases (and they are the great majority) in which the intellect, the affections, and the passions, are jointly implicated, whether there be a single delusion or several de- lusions, or merely some one excited emotion or passion, the source of a thousand changing fancies. This inquiry will prepare the way for an examination ol" the plea of insanity in criminal cases — a subject of great interest and importance. 1. In Mania, consciousness, memory, and reason may remain intact, and that even in the midst of the most violent paroxysms. The opinion, to which reference has just been made, that mania is in all cases primarily an emotional disease is quite consistent with this pro- position. It is quite conceivable that the emotions and passions may be under constant or intermittent excitement of the most violent cha- racter, and yet that there shall be a perfect consciousness on the part of the patient of all the relations in which he stands towards others, a fi'ee use of reason, and a perfect recollection of every occurrence in which he has borne a part. It is true that in the actual paroxysm of maniacal excitement, there may be neither time nor place for acts of comparison or processes of reasoning, and that even conscience may lose all restraining power ; but that memory does remain intact, even in the most violent maniacal outbursts, there is no room to doubt. The author was consulted in the case of a lady who had been suffer- ing from mania for a long term of years, and who was subject to paroxysms of extreme violence. In one of these paroxysms she had destroyed some valuable papers belonging to her husband ; and yet after the lapse of twenty years, during an interval of tranquillity, she 180 UNSOUNDNESS OF MIND. leverted to the occurrence, and expressed her regi'ot at what had happened. Similar evidence of accurate recollection is to be found in the autobiographies and viva-voce histories of persons who have re- covered from mania. Of the intact condition of the higher feculties of the mind in the maniac's more tranquil moments no medical evidence need be adduced. It will snlfice to quote the words of Mr. (afterwards Lord) Erskine, used at the trial of Hadfield for shooting at George III, in Drury Lane Theatre, in 1800. " In all the cases," he says, "which have filled Westminster Hall with the most complicated considerations, the luna- tics, and other insane persons who have been the subjects of them, have not only had memory in my sense of the expression, — they have not only had the most perfect knowledge and recollection of all the relations they stood in towards others, and of the acts and circumstances of their lives, but have, in general, been remarkable for subtlety and acuteness. Defects in their reasonings have seldom been traceable, — the disease consisting in the delusive sources of thought, — all their de- ductions, within the scope of their malady, being founded on the im- moveable assumptions of matters as realities, either without any foundation whatever, or so distorted and disfigured by fancy, as to be nearly the same thing as their creation." The madman, then, reasons like other men, with this difference, that his delusions being stronger than the imaginations of a sane man, and his passions more violent, reason is more readily made the advo- cate of the one and the slave of the other. The same observations which apply to the reason apply to the other faculties of the mind. The senses are most apt to rebel ; but even they are unsuccessful in their revolt- The delusion is too sti'ong even for them. 2. The senses are deceived and confsaughton, in the able exposition of the law by the lord chancellor before the House of Lords, by the law lords who spoke on that oc- casion, and, lastly, by all the judges to whom this grave question was referred. There can be no doubt, then, that the legal test at present received is the power of distinguishing right from wrong. But the difficulty of applying this test in practice is so great that judges ©ften, and juries always, prefer a more easy and reasonable mode of procedure. Thus, in the case of Hadfield, Lord Kenyon, with the concurrence of the rest of the judges of the Queen's Bench, inteiTupted the defence, and said that " with regard to the law, as it had been laid down, there could be no doubt whatever. If a man be in a deranged state of mind at the time of committing an act, he is not criminally answerable ; the material part of the case is whether, at the very time, his mind was sane. His insanity must be made out to the satisfaction of a moral man meeting the case with fortitude of mind, and knowing the anxious duty he has to discharge." Here, then, the distinction between right and wrong is altogether lost sight of, and the simple practical question of the insanity of the accused is made to take its place. As 188 UNSOUNDNESS OF MIND. a general rule, however, the theory and practice of the law have been so far consistent, that though the verdict of the jury has been couched in general terms, the test of right and wrong hiis been distinctly pro- pounded from the bench. In the case of M'Naughton, for instance, the jury brought in a verdict of " not guilty, on the ground of in- sanity," after Chief Justice Tindal had in his charge strongly and clearly laid down the distinction of right and wrong. The state of the law up to a recent date, and, indeed, up to the present time, may be inferred from the answers of the fifteen judges to the questions suggested by the trial of M'Naughton. These questions were submitted by the judges to the House of Lords, and the answers, in which the whole bench, with the exception of Mr. Justice Maule, concuiTed, were read to the house by Lord Chief Justice Tindal on the 19th June, 1843. From these questions and answers given in extenso at the foot of this page,* the present state of the law in respect of * Question I. What is the law respecting alleged crimes committed by persons afflicted with insane delusion, in respect of one or more particular 8ui> jects or persons : as, for instance, when at the time of the commission of ilie alleged crime the accused knew he was acting contrary to law, but did the act complained of wiih the view, under tlie influence of some insane delusion, of redressing or avenging some sujyposed grievance or injurj'-, or of producing some supposed public l)eneflt?- Answer. Tlie opinion of the judges was, that, not uithstav ding the party committed a icrong act, while labouring under the idea that fie was redressing a supposed grievance or injury, or under the im- pression of obtaining some public or private benefit, he was liable to punish- ment. Question IL What are the proper questions to be submitted to the jury, when a person alleged to be ahected with insane delusion, respecting one or more particular subjects or persons, is charged with the commission of a crime (murder, for example) and insanity is set up as a defence?— Answer. The jury ought in all cases to be told that every man should be considered of sane mind until the contraiy were clearly proved in evidence. That before a plea of in- sanity should be allowed, undoubted evidence ought to be adduced tliat the accused was of diseased mind, and that at the time he committed the act he vias not conscious of right and vyrovg. This opinion related to every case in which a party was charged with an illegal act, and a plea of insanity was set up. Every person was supposed to know what the lav) was, and therefore nothing could justify a wrong act except it was clearly pi-oied that the party did not know right from wrong. If that was not salistactoriiy proved, the accused was liable to punfthraent ; and it was the duty of the Judge so to tell the jury when summing up the evidence, accompanied by those remarks and observa- tions which the nature and peculiarities of each case might suggest and require. Question 111. In what terms ought the question to be left to the jury as to the prisoner's state of miud at the time when the act was conmiitted ? No answer. Question IV. If a person, under an insane delusion as to existing facts, com- mits an offence in consequence thereof, is he hereby excused ?— Answer. If the delusion were only partial, the party accused was equally liable with a person of sane mind. If the accused killed amther in self-defence, he would be en- titled to an acquittal ; but if the crime were committed for any supposed injury, he uould then be liable to the punishment awarded by the laws to his crime. Question V. Can a medical man, conversant with the disease of Insanity, who never saw the prisoner previously to the trial, but who was present during the whole trial and the examination of all the witnesses, be asked his opinion as to the state of the prisoner's miud at the time of the commission of the alleged yi.. .,:-./, PLEA OF INSANITY IN CRIMINAL CASES. 189 homicidal acts, committed by persons afflicted with mania accompanied by delusions, may be inferred to be as follows : — That a person who commits an act under the influence of an insane delusion, with a view of avenging some supposed injury, redressing some supposed grievance, or producing some supposed public benefit, is liable to punishment, if, at the time of committing the act, he knows that it is contraiy to law ; and that if the delusion is only partial, the respon- sibility incurred is equal to that attaching to a person of sound mind. It further appears that before the plea of insanity can be allowed, it must be proved in evidence that the accused was of diseased mind, and that at the time of committing the act he was not conscious of right and wrong. He is assumed to know what the law is, and is only held irresponsible for his act if his mind can be shown to be so unconscious of right and wrong that he is incapable of appreciating the law and its requirements. This is the only reasonable interpretation which can be given to the doctrine of the judges. " Every person was supposed to know what the law was, and therefore nothing could justify a wrong act, except it was clearly proved that the party did not know right from wrong." Four distinct questions are suggested by this brief summary of the decisions of the fifteen judges. 1. Are the class of maniacs now under consideration (namely, those who commit acts of violence under the influence of delusions, and with premeditation) cognizant of the law ? 2. Can they distinguish right from wrong ? 3. Do the answers to these questions apply to persons subject to partial delusions? 4. Are these legal and moral tests of any practical utility? 1 . Are maniacs, who commit premeditated acts of violence under the influence of delusions, cognizant of the law ? The answer to this question is easy. There is every reason to believe that these persons possess the intelligence and consciousness requisite to the knowledge and appreciation of the law. They have been shown to be as a class by no means wanting in memory, observation, or reasoning power. Some of them have committed murder that they might suffer the penalty of the law ; those who, from being placed under restraint, have grown conscious of their infirmity, know or believe that they are by that in- firmity rendered irresponsible, and it is in the last degree improbable crime, or his opinion whether the prisoner was conscious, at the time of doing the act, that he was acting contrary to law ? or whether he was labouring under any, and what delusion at the time ? — Answer. The question could not be put in the precise form stated above, for by doing so it would be assumed that the facts had been proved. When the facts were proved and admitted, then the question as one of science would be generally put to a witness under the circumstances stated in the interrogatory. Mr. Justice Maule dissented from the answer to this last question. In his opinion such questions might be at once put to medical men without reference to the facts proved ; and he considered that this had been done, and the legality of the practice thereby confirmed on the trial of M'Naughtou. 190 UNSOUNDNESS OF MIND. that monomaniacs whose intellects appear to be so little affected that they are allowed to mingle in society like other men, should be igno- rant of a law with which ft-om their earliest years they have been familiar, and of which we are all, unfortunately, too often reminded. The knowledge and consciousness of this law may be fairly expected to be the very last of which madness would deprive a man. 2. Can they distinguish right from wrong'? There is reason to believe that the class of maniacs now under consideration are conscious of the difference between right and wrong, and if asked whether murder is an offence against law, divine and human, would answer unhesitatingly in the affirmative. But there is equally reason to believe that if a maniac subject to delusions were to conceive the desire to commit murder, he would be as incapable of resisting that desire as he had already proved himself incapable of resisting his delusions. There is a fair and reasonable analogy between the insane thought and the insane wish. His delusions have already defied the evidence of his own senses, the efforts of his own reason, the tes- timony of his sane neighbouis, and the remonstiances of his friends ; and his impulses will ])robabIy prove as irresistible when confronted with his knowledge ot the distinction between right and wrong and the remonstrances of his conscience. 3. Of partial deltisions. It is natural to suppose that a maniac subject to a great number of delusions would be less able to control his irregular impulses than one who has but one or two delusions. A multitude of delusions naturally implies more confusion and more excitement. A single delusion may be supposed to be moie compatible with self-restraint. Single delusions are, however, of rare occurrence, and do not oft«n figure in couits of law. Partial delusions are much more common, but when they are closely examined they are found to be the offspring and natural expression of some one excited feeling or passion, which, having had strength enough to create illusions of the senses and delusions of the mind, may be expected to give rise to insane impulses of great power. The excited feelings or passions which, having first destroyed the integrity of the senses and mental faculties, proceed to instigate acts of violence and ciuelty, are religious excitement or despondency, and jealousy. Domestic anxieties exaggerated into fear of starvation, and discontent transformed into an insane belief in persecution, are also fruit- ful sources of illusions, delusions, and acts of violence. Now the acts of violence which ultimately flow from these excited feelings or passions, after they have given rise to a series of delusive ideas, ought to be judged by the same rules which apply to the delusions themselves. The acts are probably as little subject to resti-aint as the delusions to conection. If the four most common sources of homicidal acts — religious excite- ment or despondency, jealousy, domestic anxiety, and discontent — are submitted to further analysis, the objection to the plea of insanity will be found to be narrowed to a small number of cases. PLEA OF INSANITY IN CRIMINAL CASES. 191 Maniacs under the influence of religions excitement or despondency are subject to illusions and delusions of a very singular kind. They frequently transform the persons with whom they are associated into supernatural beings, endowed with authority or power not to be ques- tioned or resisted, and they convert common and familiar sounds into the articulate language of temptation or command. One religious maniac, therefore, kills a relative or a keeper, imagining him to be a beast, or a fiend ; another has an honest conviction that he is above the law. Perhaps he believes himself to be the Deity, or that he is commissioned by him to fulfil some mission of wrath or extirpation. In cases of religious mania, then, we can never confidently affirm that the criminal act was not the natural consequence of a delusion which placed the maniac, in his own sincere conviction, beyond and above the operation of human laws ; or of a command which he would deem it impious to resist. Of homicidal acts instigated by jealousy shaping itself into a distinct delusion it will suffice to observe that they are such acts as if com- mitted by sane men on the evidence of their senses, would be punished as manslaughter and not as murder. Of the infanticides committed by fathers and mothers under the pres- sure of domestic anxiety culminating in an insane dread of starvation, it may be observed that they are the acts of parents generally remarkable for their domestic virtues and devoted attachment to their victims, and that between them and ordinary murderers there is no single point of resemblance. Discontent, transformed into an insane belief in persecution, presents greater difficulties. The case against the insane believer in persecution is generally put in a form which seems to preclude a satisfactory answer. A maniac believes himself to have been injured by another, and he takes away his life. If the injury were real instead of imaginary, the murderer would be responsible for his act, and so, it is contended, ought the madman to be. This argument would be valid if all the concomitants in the two cases were the same ; but, in reality, they have nothing in common but the act itself. The imaginary offence has iraaginaiy accompaniments, and every thought connected with it is one of confusion. The supposition that the mind which can imagine an impossible offence is sound in all other respects is opposed to the strong conviction of all men of experience among the insane. They all with one consent repudiate the notion of a mind subject to such a delusion being sound, and free to act as it will, beyond tlie sphere of its influence. The more closely the subject of this partial delusion is observed, the more extensive is found to be the disorder of his intellect. Those actions which are not directly prompted by his delusion are more strange, and his passions are more excitable than those of other men. The theory of a single insane idea springing up in the mind, unaccom- panied by any other disordered action of the faculty from which it takes its rise» having no effect upon the remaining faculties, and showing 192 UNSOITNDNESS OF MIND. itself simply by prompting an action, which, when once suggested, is carried out with the complete consciousness of its real nature which exists in the mind of a sane man acting under the suggestion of a cor- responding reality, is too absurd to be for one moment entertained. Even in this case, therefore, the question of responsibility cannot be decided by the simple test of a knowledge of right and wrong. But there is another case allied to the one now under consideration which presents still greater difficulties. A man receives a real injury, and he avenges himself; but it is alleged that he was not of sound mind when he committed the act. The unsoundness of his mind is admitted, but he is deemed responsible as committing murder under the instigation of the common motive of revenge. On the other hand, it is reasonable to allege that the real injury has been by his insane mind magnified to an undue importance, and then acted upon just as if it had been altogether imaginary ; that he is therefore neither more nor less responsible for his act than the man whose motive was from the fust purely imaginative. In this case, too, an inquiry into the state of mind, extending much beyond the legal test, will be necessary, and cannot be refused ; and this very inquiry, once granted, must result in showing the insufficiency of the test. Even in those cases where the criminal act cannot be traced to any delusion of which it is the legitimate offspring, but it is simply alleged in defence that the party is of unsound mind, the very fact of the unsoundness becomes an irresistible plea in mitigation. It would be strange, indeed, if the case of the unhappy maniac under the accusation of crime were the only one in which such a plea is ignored and refused. 4. Are these legal arid moral tests of any practical utility ? If the utility of a test is to be measured by the facility of its application, this test of a knowledge of right or wrong Will certainly be condemned. It fails in the hands of the medical witness, it is often practically set aside by our judges, and it is never really applied by our juries, as the very form of their verdict shows. In most cases it is comparatively ]- easy to ascertain the fact of unsoundness of mind, but it is impossible to determine the precise effect of that unconsciousness upon the mad- man's acts. But it is eminently absurd to credit a mind which is already occupied by delusions with an otherwise efficient state of its faculties. It is in the highest degree improbable that a mind so pos- sessed is able, beyond the sphere of its delusions, to think, feel, and act with the clearness, force, and freedom of the sane. Some writers, under a strong sense of the failure of the legal test of a knowledge of right and wrong, have sought to set up in its place the power of control or restraint. The test has been thus transferred from the intellect to the will— from the knowledge of right to the power of acting aright. But this is a mere shifting of the difficulty. It is obviously quite as easy to ascertain a man's abstract knowledge of right and wrong, lawful and unlawful, as the exact amount of self- restraint which he possesses. PLEA OF INSANITY IN CRIMINAL CASES. 193 This test appears to have one advantage over the knowledge of right and wrong. Jt is thought that the mode of accomplishing the homicidal act will itself throw light on the amount of restraint or self-control which the maniac is able to exert. If he watches his opportunity, bides his time, prepares a fitting instrument, and uses it in the ordinary way, it is infeiTed that he possessed such an amount of self-control as ought to have prevented the murderous act. The objection to this test is obvious. It is drawn from the analogy of the madman's sensations and thoughts. If he could not prevent the senses from being the sport of illusions, and was unable to root out delusions from his mind, it is not to be supposed that he can control the irregular impulses and passions which are to the will what illusions are to the senses or delusions to the intellect. And if it is alleged that the skill evinced in planning the homicidal act, and the patience shown in wait- ing for a favourable opportunity, ought to be taken as evidence of adequate self-control, appeal may again be made to analogy. The acts of the maniac are in strict keeping with his thoughts. His delusions, even when they are most distinctly present to his mind, are quite compatible with the exercise of all his faculties. If they are attacked, he defends them acutely and justifies them plausibly. They have not destroyed his faculties, they have merely perverted them to a wrong use. So is it with his homicidal act. The impulse which seizes upon his unsound mind does not destroy his powers, it merely perverts them. Accordingly, if a maniac is under the delusion that his keeper is a fiend, or if he believes that the Deity has commissioned him to take away the keeper's life, he will load a pistol, watch his opportunity, and act in every respect as a sane criminal would do. And, if prevented on one occasion, he will wait for a more favourable opportunity. Nay, the merest imbecile knows that a knife or a pistol is a common instrument of death ; and weak as his mind may be, he conceals his weapon, not because he is conscious of guilt, but because he knows that, if it were openly displayed, the action he contemplates would be prevented. The fact is, that in proposing this test, as in the general discussion of this question, two distinct things have been confounded, —the act itself, which is the result of the delusion, and the mode of accomplishing it. It is the delusion which distinguishes the madman and not the mode in which the delusive impulse is carried into effect. This test, then, is open to the same objections which lie against the legal tests : it seems reasonable, but it is not practical. The difficulty of devising a test which shall not be open to the most serious objections has led some persons to devise an easy method of escape by depriving persons of unsound mind of what is called the privilege of insanity, or, in other words, refusing to entertain the ques- tion of the state of the mind at all. This suggestion may have the merit of simplicity, but it is open to the very serious objection that it could be acted upon only once. The spectacle of a madman on the o 194 UKSOUXDNESS OF MIKD. scaflFold would be simply intolerable. No jury conld be found to con- vict ; and the indiscriminating statute would prove as complete a dead letter as the statute which awards the punishment of flogging to assaults upon the Queen did, when it was to be applied to the person of poor Lieutenant Pate. The idea of hanging and flogging madmen is utterly repulsive, and must be given up. Anothei- theory entertained by some writers of eminence is, that as madmen are, like other men, influenced by fear, the punishment of death, as the consequence of murder, should be kept before their eyes. This theory may be said to have broken down in the case of Lieutenant Pate, just referred to. It is most probable that this poor imbecile was cognizant of the degrading punishment awarded by a recent statute to persons who should assault the sovereign ; but the thieat had no effiect upon him. By parity of reasoning, it seems most probable that the threatened punishment of death would prove equally ineffectual in every class of madmen. But, in reality, the restraining influence ot" the punishment of death is already brought to bear upon persons of unsound mind ; for it should be borne in mind that men who have not been certified as insane, and confined in lunatic asylums, do not believe themselves to be mad. They are, in their own sight, sane men. It is only after men have been taught, by confinement as madmen, that they are insane, or are believed to be so, that the terror of the gallows is replaced by the alternative terror of perpetual imprison- ment. Those who maintain the theory now under examination are apt to defend it by comparing persons of unsound mind with the lower animals, alleging that, as dogs can be weaned by punishment fi-om practices distasteful to their masters, so madmen can be deterred from crime by fear of death. In putting forward this argument from analogy two facts are overlooked — the fact that the animal has been punished, and has a distinct recollection of the pain inflicted upon him, while the madman has been merely threatened ; and the fact that there are many dogs who cannot be weaned from bad habits by the frequent repetition of the most severe chastisement. In the case, then, of the class of maniacs now under consideration, who, being subject to delusion, commit their acts of violence with pre- meditation, it is submitted that all the legal and moral tests are inapplicable and useless ; and that the law of England ought to be as- similated to that of France — " II n'y a ni crime ni de'lit lorsque le pre'venu e'tait en etat de demence au temps de Paction." It may be objected that under such a law, unless the most rigid proof of insanity were required, some men would escape who ought to suffer the punishment of death : but, on the other hand, none who did not deserve death would be executed; and it is a generally acknow- ledged principle, that it is better that many guilty persons should escape than that one innocent man should suffer. Moreover, a verdict of acquittal, on the giound of insanity, bi'ings with it, as a necessary PLEA OF INSANITY IN CRIMINAL CASES. 195 consequence, confinement for life, which, were it inflicted as a punish- ment, would hardly be second in severity even to death itself. Nor is there any good reason to fear that, ])y exempting the madman from the punishment of death, we shall weaken the hold which the law has on the man of sound mind ; for, in order that he may escape death, he must successfully feign insanity — a task of no ordinary difficulty — and, if he succeed, a perpetual sacrifice of liberty awaits him. It is not likely, therefore, that society will suffer any injury from the adoption of the course here advocated ; and we may peihaps find that it gains something by openly attributing to disease some of the most revolting crimes which degrade and debase our common nature. In respect to the responsibility of madmen, then, the law seems to be in this dilemma: — it must either insist upon a test which it is impossible to apply, or it must uniformly refuse or admit the plea of insanity. If it hold to a test, its decisions will want that uniformity which ought to belong to them, and their soundness will be constantly liable to be called in question ; if it reject the plea of insanity it ought forthwith to do away with all other pleas in mitigation. The foregoing observations apply to those cases only in which dis- tinct proof has been obtained of unsoundness of mind, existing pre- viously, as well as at the very time of the criminal act, and not to that instinctive madness which is altogether independent of the intellect, and consists merely in uncontrollable impulse. This form of madness is now generally recognized by medical men, and has on more than one occasion led to the acquittal of an accused party. The criminal acts committed under its influence have most or all of the following characters : — They are without discoverable motive, or in opposition to all known motives. A man kills his wife to whom he is tenderly attached, a brother his sister, a mother her infant ; or the victim is one whom the madman never saw before in the course of his life, and against whom it is impossible that he can bear any malice. After the commission of the act, he does not seek to escape ; he often publishes what he has done ; does not conceal the body from view, but openly exposes it ; delivers himself up to justice ; describes the state of mind which led to the act, and either remains stupid and indifferent, or is overwhelmed by remorse. He has no accomplices, has made no preparations, and takes nothing from his victim. Sometimes he has previously spoken of his strong temptation, and begged to be prevented from doing mischief. These homicidal acts are generally preceded by a striking change of conduct and character, and, on inquiry, the accused is often found to have an hereditary tendency to insanity, to have attempted suicide, to have expressed a wish for death, or to be executed as a criminal. In this class of cases it is most important that all the circumstances should be duly weighed, and that careful search should be made after those motives which most frequently actuate the criminal. It is in 196 UNSOUNDNESS OF MIND. such difficult cases, too, that a caution is especially necessary against basing a decision upon one or two alleged characteristics. All the cir- cumstances of the act ought to be duly weighed, in the spirit of the words of Lord Hale : " lest, on the one side, there be a kind of inhu- manity towards the defects of human nature, or, on the other side, too great an indulgence given to great crimes." This instinctive madness is no doubt sometimes associated with delusion, the criminal act itself being the result of strong excite- ment of the passions, while the delusion suggests the motive. To this class probably belong those cases of wholesale murder in which the father of a family destroys his wife and children, to prevent them from falling victims to stai^vation, and then puts an end to his own life : the idea that such an evil threatens them being insane, no less than the impulse which prompts such a mode of escape. In order to complete this inquiry into the plea of insanity in criminal cases, it would be necessary to enter into minute details respecting the different aspects given to criminal acts by tiie several varieties of unsound mind. The want of space for so full a discussion of the subject leads me to substitute the following brief summary : — An imbecile has a confused and imperfect notion of crimes, laws, and punishments ; and his acts are as foolish as his thoughts. The case referred to at p. 164 is a good example of crimes committed by this class. A monomaniac fancies himself an object of persecution, and he murders one of his imaginary tormentors. His act is as mad as his thought. He destroys one of his supposed enemies, and hopes thereby to rid himself -of all. Such was M'Naughton. Another having betrayed decided symptoms of madness, receives a real injury, and murders the person who has injured him. Such was Lord FeiTcrs. A third, oppressed with melancholy fears, kills those to whom he is most attached, to save them from some imaginary fate. Such was the female already referred to, who, under the fear of starvation arising out of temporary difficulties, murdered her child, cooked it, ate of it, and offered the dish to her husband. Lastly, we have the so-called instinctive madness, of which the case of William Brown, given at length in Kay's 'Medical Jurisprudence of Insanity,' affords a good example. FEIGNED UNSOUNDNESS OF MIND. Men feign insanity from the same motives which lead to the simu- lation of other diseases. Of this class of feigned diseases, too, as of those already noticed at greater length at p. 145, it may be stated that it is only by actual experience of the real disease that the counter- feit can be detected. Indeed, this remark is generally acknowledged to be peculiarly applicable to feigned insanity. • . Idiocy. — This form of mental unsoundness is rarely assumed, and, when feigned, is easy of detection. The idiot has almost always a FEIGNED MANIA. 197 peculiar form of head, accompanied in most instances by other de- formities ; and it must always be practicable to learn so much of an impostor's history as that he was not always in the condition which he has assumed. Imbecility. — In this case, too, the history, where it can be obtained, will assist in unmasking the imposition ; and where the previous history is unknown, the patient, by assigning his unsoundness to some inadequate cause, may assist us in our diagnosis. The peculiar cast of countenance of the imbecile is extremely dilficult to imitate. The dull, stupid, vacant, and wandering look, corresponding with the unsettled and uneasy manner, the disconnected and evanescent ideas, the variable temper and spirits, the sudden and transient gusts of passion, and the foolish acts utterly unsnited to bring about the objects he professes to have in view, are, collectively, very difficult to assume. In the less strongly-marked forms of real imbecility, folly and acuteness are dis- played indifferently on all subjects ; but the impostor is shrewd on those which involve his interest or the success of his scheme, and dis- plays his stupidity only in matters of indifference. This class of cases, however, piesents unusual difficulty of diagnosis, and gives rise to great differences of opinion among medical men. Several cases have come under the notice of the author of imbeciles certified as insane by the medical officers of prisons, and returned from the asylums as impostors ; and other cases in which, after long and careful observation under the most favourable circumstances, two equally competent observers have not been able to agree in their opinion. Unsettled habits, wandering and disconnected thoughts, sudden bursts of passion, unprovoked acts of violence, imsuccessful attempts at suicide, transient and half-formed delusions, short fits of industry, handywork displaying much skill and ingenuity, make up a combination which it would be in the power of a good actor to assume. But imbeciles of this order possess sufficient shrewdness and self-control to conceal and moderate their eccentricities when they have an object to accomplish. So that it is quite possible for a real imbecile in prison to seem an impostor in an asylum. Dementia. — This form of unsoundness is rarely imitated. That torpor of all the faculties which belongs to the true disease is not readily put on and sustained ; and we shall be much assisted in our diagnosis by bearing in mind the fact that dementia, where it is not the result of a sudden and severe mental shock, is the consequence of a disease of the brain, which, sooner or later, reveals itself in paralysis. Mania. — As it is more easy to assume the violence of mania than the more subdued characters of the foregoing forms of unsoundness, mania is more frequently feigned. The distinction between the fic- titious and the true disease, though occasionally requiring time and continued observation, is not difficult; but in this, as in other feigned diseases, the impostor often obstinately resists the efforts of the medical man to obtain a confession of his fraud. 198 UNSOUNDNESS OF MIND. The peculiar intense expression of the countenance, the marked al- teration of the features, and the wildness of the eye, which belong to real mania, can scarcely be successfully assumed. The vehement ex- citement, the loud shouts, the strong struggles, and violent convulsive movements of the paroxysms also scarcely admit of imitation, and cannot be supported for any length of time. 'i'he real maniac will continue without sleep for days, and even weeks, or, if he sleep at all, his rest will be disturbed and agitated; but the impostor can scarcely keep himself awake beyond one or two days, and a dose of opium, which would produce no effect whatever upon the madman, would infallibly send the impostor to sleep. The same remark applies to other remedies, such as emetics and purgatives. The madman will also go without food for days together with impunity, and with little loss of strength. Another character of true mania is insensibility to external impressions. The maniac will also bear the most intense cold, and gaze without being dazzled on the strong light of the sun. Other symptoms of less importance have been insisted on, such as the torpid state of the bowels, the moderate or low temperature of the trunk and limbs, a peculiar odour of the skin, and a frequent pulse.* To this account of the physical signs of mania it may be added that the impostor is apt to overact his part during such times as he is watched ; that instead of becoming more quiet and reserved on the approach of the physician, his violence increases ; that he assumes a want of intelligence instead of that perversion of reason which is so characteristic of the real affection ; that he obtrudes instead of conceal- ing his thoughts ; that he pretends a defect of memory and appre- hension which does not belong to real insanity, gives false answers to questions, and affects not to recognize persons whom he knows; that he does not recur constantly to the leading idea ; that he betrays hesi- tation in the midst of his assumed violence ; that he has not the steady gaze of the madman ; that his fits occur suddenly and at irregular and convenient intervals, instead of having the periodicity of intermittent attacks of mania. Il^may be added, that instead of having the long period of incubation so general in true mania, the first attack of his disorder is sudden. That perversion of the moral feelings which causes the madman to dislike every person to whom he was previously at- tached, being a symptom little known to the vulgar, is also not assumed by the impostor. Besides the diagnostic marks to be gleaned from the foi'egoing description, and the precautions already mentioned under the head of feigned diseases, some special tests have been recommended ; such as repeating to the suspected person a series of ideas recently uttered * In the first edition of this work I adduced facts to show that the value of the pulse as a diagnostic mark had probably been exaggerated. All, perhaps, that can be safely afHrmed is that an Infrequent pulse, which often exists in healthy persons, would scarcely be compatible with mania. FEIGNED MANIA. 199 when the real maniac will introduce new ideas, but the impostor will deem it expedient to repeat the same words. The use of the whirling chair is also recommended, as producing giddiness and nausea in the impostor. Partial Intellectual Mania. — Monomania . — Melancholia. — These partial forms of mania are less frequently feigned than general mania, and rarely with success. Many of the characters of mania already described are present in cases of intellectual mania springing out of some excited motion, sucli as pride or vanity. There is the same irritability of temper, the same violent prejudices, the same unfounded aversions and equally unfounded attachments, the same sleeplessness, the same insensibility to impressions, and to the operation of medicines. The pretended monomaniac makes a more open display of his assumed delusion than the real monomaniac, who rarely solicits attention. The true monomaniac is generally reserved, taciturn, and indifferent, but is easily excited and angered by opposition and argument. When hard- pressed men generally take refuge in violence and women in tears. The forms of intellectual insanity most commonly assumed, and most difficult to distinguish, are those which consist in the assumption of a single delusion, or of profound melancholy ; and it is obviously difficult to lay down any diagnostic mai'ks by which the real disease can be distinguished from the false. The difficulty of diagnosis is seriously enhanced when, as sometimes happens, the malingerer is a good actor, and makes a faithful copy of the words and acts of a madman with whom he has been brought in contact. Moral Mania, general and partial. — As the character of the act or acts committed is the chief ground for believing in the existence of this form of unsoundness, there is no certain means of distinguishing the real from the feigned disease. It is, however, so unlikely that n sane man would commit a murder, for which no motive could be dis- covered, with the certainty of being hanged if found sane, and im- prisoned for life if pronounced mad, that we may fairly assume a homicide, accompanied by all or many of the characters already pointed out, to have been the result of real moral insanity. The personal and family history of the accused would also afford some presumptions in favour of or against the theory of insanity. Of general moral Insanity it may suffice to state that the strange combination of foolish, obscene, and cruel acts which make up the history of the true disease, places a serious difficulty in the way of the impostor. Concealed Insanity. — The power of concealing his delusions, under the influence of a sufficiently strong motive, has already been shown to belong to the madman ; and long-continued observation, repeated interrogations, and careful inquiry into the patient's previous history may be necessary to bring the delusions to light. 200 RULES FOR THE EXAMINATION OF PERSONS RULES FOR THE EXAMINATION OF PERSONS SUPPOSED TO BE OF UNSOUND MIND. Under this head it is proposed to give a few simple directions as to the chief points to be attended to in the several examinations which the medical man may be required to institute. 1. Observe the general appearance of the individual, the shape of the head, the conformation of the body, the expression of the counte- nance, the gait and movements, and the speech. 2. Ascertain the state of the general health, and note whether the complexion is pale or florid, and the skin moist or dry. Inquire into the state of the digestion, whether the appetite is good, bad, or variable, an It is confined to the muscular system ; for so long as the muscles remain entire, the limbs continue inflexible, unless great force be used ; but when they are cut or torn, the rigidity ceases. It takes place in ail positions of the body, and whether the limbs be flexed or extended, and it does not change the positions which the several parts of the body had at the time of death. It shows itself first in the muscles of the trunk and neck, then in those of the upper extremity, then in those of the lower ; and it disappears nearly in the same order ; the muscles of the lower extremity often remaining rigid when those of the trunk and upper extremity have resumed their state of relaxation. It is entirely independent of the nervous system, for it makes its appear- ance after the nerves have ceased to be excited by the galvanic fluid. A division of the nerves, or even the removal of the entire brain, does not prevent its occurrence ; and in death from apoplexy or 212 REAL AND APPARENT DEATH. hemiplegia, the paralyzed limb is affected in the same way, and to the same extent, as the sound one. Cadaveric rigidity is strongly marked and persistent in muscular subjects, and, as a general rule, it lasts long wlien it sets in late. In death by lingering diseases, such as low fever, consumption, and scurvy, and the diseases of old age, the rigidity sets in very speedily, and disappears again in the course of one or two hours. On the other hand, in death by acute inflammation of the stomach or viscera, by irritant poisons, whether minei-al, vegetable, or aerial (provided they exert no specific influence on the contractile powers of the muscles), the rigidity is for the most part slow in making its appearance, strongly developed, and lasts for a considerable time. After death from spasmodic cholera it is said that rigidity has commenced very early, and has not ceased till after the lapse of four or five days. It is slow in showing itself in death from apoplexy, haemorrhage, wounds of the heart, decapitation, injuiy of the spinal marrow, and asphyxia. Its duration in poisoning by carbonic acid is very considerable, and in one case Nysten found that it continued seven daj'^s. On the other hand, in poisoning by sulphuretted hydrogen gas, rigidity does not occur. Cadaveric rigidity cannot be mistaken for any other condition of the dead body. The stiffness caused by intense cold would be readily distinguished fi om it by the ease with which the limbs are moved. The rigidity of the muscular system present during life in such diseases as catalepsy and tetanus does not need to be distinguished from cadaveric rigidity. If any distinction were necessary, it might be drawn from the effect of bending an extremity forcibly: if the rigidity were due to a vital contraction, the limb would be restored to its position, whicli would not happen in the rigidity of death. Rigidity, then, is a certain sign of death, and a state not to be con- founded with any existing in the living body, or in any form of apparent death. Supervening, too, as it does, after the extinction of muscular irritability, it is a sure indication of the hopelessness of our attempts at resuscitation. Putrefaction. — This, too, is an infallible sign of death, not re- quiring to be distinguished from any condition of the living body. As the march of the putrefactive process affords some means of judging of the period at which death took place, it will be necessary to describe the changes which it occasions in the body with some degree of minuteness. In the intei-val which elapses between the extinction of life and the commencement of the putrefactive process, the body falls more and more under the influence of physical laws. The skin loses its elasticity, and the flesh its firmness, and the blood, which was equally distributed through the body by the action of the heart and the elasticity of the arteries, now obeys the laws of gravity, and falls to the most depending parts of the corpse. Hence the paleness of some parts and the deep violet tint of others, the discolouration of the SIGNS OF DEATH. CADAVERIC LIVIDITY. 213 occiput and back, of the depending parts of the intestines, and of the posterior part of the lungs. As the body is usually placed on the back, this cadaveric lividity is found on the posterior parts of the body and of the internal organs ; but if the body be placed on the face, it will occupy the anterior part of the body and of the viscera. If again, after discolourations have formed on the back, the body be turned while still warm, and before the blood has coagulated, they will disappear. These discolour- ations are often very extensive, and, if the body is placed on a -smooth surface, uniform in tint ; but if the surface is uneven, the discolour- ations are interrupted and irregular. The pressure of the clothes produces the same effect ; so that a careless observer might mistake the marks of clothes ftistened round the neck for the effect of strangulation, or isolated patches for severe bruises. The extent and amount of discolouration are pi'oportioned to the quantity of the blood which the body contains ; the general prevalence, therefore, of cadaveric lividity through the whole body indicates a general fulness of the vascular system. On the other hand, its absence shows that a small quantity of blood exists in the body. Sudden death unattended by haemorrhage or effusion of blood, is characterized by ex- tensive lividity ; but after death preceded or caused by hajmorrhage, the skin is remarkably pale, and presents but faint traces of such dis- colouration. This subsidence of the blood explains a fact of some medico-legal importance, namely, the diminished intensity of colour in parts which had been the seat of the less severe and more diffuse forms of inflam- mation. But the appearance produced by such acute inflammation as follows burns and scalds, blisters, and strong friction on the surface, and the action of the more violent irritant poisons on the internal parts, are permanent, and quite distinct in the dead body. Cadaveric lividity is said to be distinguished from the effect of injuries inflicted during life by the seat of the discolouration being in the rete mucosum and vascular membrane which lie exterior to the true skin. The vessels of these parts are filled with dark blood, so that the cut surface presents a black line from which the blood may be expelled by pressure. The dermis or true skin is white. But in the discolourations of the skin produced by the afflux of blood daring life the tissue of the true skin is injected with blood, and exhibits when divided a number of bloody points. This discolouration of the tissues external to the true skin, is, however, not an invariable occurrence ; for on comparing a vertical section of the integument from a part of the back deeply discoloured by cadaveric lividity, with a similar section from a highly inflamed portion of skin, the first was found to be quite free from vascular injection, while the last presented a number of red spots of extravasated blood. The two sections were mounted side by side, treated in every way the same, and examined by the same power of the microscope. 214 REAL AND APPARENT DEATH. Besides these discolourations produced by the blood which follows the course of the vessels, there are others due to the transudation of the fluids. Thus the parts in immediate contact with the gall-bladder are deeply tinged with bile ; and the aqueous humours of the eye transuding, cause the dull and collapsed appearance of the cornea. The subsidence of the blood and the transudation of the fluids partly explain that relaxed and softened state of the tissues which is the first of the series of changes usually attributed to putrefaction. These fluids next undergo changes of colour, and tinge the several textures with brown, blue, or green discolourations, according to the degree of decomposition which they have undergone. The exudation of fluids is followed by the development of gases in the several cavities of the body, especially in the abdomen. This takes place sometimes so rapidly, and to such an extent, as to change the position of the body. In consequence of the resistance offered by the walls of the abdomen and chest, the internal viscera and their contents suffer displacement. The diaphragm is thrust upwards, the contents of the large vessels are forced towards the head and neck, the face swells, the eyes become prominent, and a mucous or bloody fluid flows from the mouth and nostrils. In rare instances the contents of the bowels are forced out. Blood also exudes from wounded or ruptured vessels, leading to post-mortem haemorrhages and extravasations. Of old, much importance was attached to this post-mortem bleeding of wounds, and if it happened to coincide with the touch of the criminal supposed to have inflicted them, he was summarily convicted of the murder. There is reason to believe that the development of gas (probably carbonic acid) in parts of the body filled with blood often precedes the other common signs of putrefaction. I have seen this early foi-mation of gas both in the lungs and beneath the membranes of the brain. (See Infanticide, p. 89.) As putrefaction advances, the cuticle becomes detached, the muscles grow viscid and pulpy, assume a dark- greenish colour, and exhale a highly offensive odour ; and at length the whole texture of the body becomes changed into a soft semi-fluid mass, which gradually parts with its moisture, dries up, and leaves a fibrous fatty residue, slowly lost in the soil. Sometimes these processes of putrefaction and decay go on very rapidly, and are soon completed ; at other times they are extended over many years, the rapidity with which they take place depending greatly upon the circumstances in which the body is placed. When the process of putrefaction is once established under favourable circum- stances it goes on rapidly, the parts already decomposed acting as a sort of leaven to the rest. The conditions which affect the progress of putrefaction, and enable us to form an opinion as to the time at which death took place, are Temperature, Moisture, and Access of air. Period, Place, and Mode of Interment, Age, Sex, Condition of the Body, and Cause of Death. SIGNS OF DEATH. PUTKEFACTION. 215 Temperature. — Putrefaction is arrested by a temperature of 212° and of 32° : in the former case the body is reduced to di-yness by the evaporation of the fluids ; in the latter the fluids are congealed. The most favourable temperature is one ranging from 70'-' to 100°. Putre- laction, therefore, takes place more rapidly in summer than in vyinter, and, other things being equal, varies with the temperature. Moisture. — This is an essential condition, and without it putrefac- tion cannot begin, or, having begun, cannot continue. The body contains, in all its parts, moisture enough to insure decomposition ; but those parts, such as the brain and eye, which contain the largest quantity of fluid are most prone to putrefaction, and dropsical subjects putrefy speedily. Putrefaction commences soon, and runs a rapid course, in inflamed parts, in bruises, and at the edges of wounds. Bodies which have remained for some time in the water, and are then exposed to the air, putrefy more rapidly than those which have not been immersed; but in bodies which remain in the water putrefac- tion goes on slowly, from the contact of air (another condition highly favourable to putrefaction) being prevented. On the other hand, dryness of the air retards or arrests putrefaction. Hence the preservation of the bodies of travellers on sandy deserts. A rapid current of air has the same effect as dry air, by causing rapid evaporation. On the other hand, a moist and stagnant atmo- sphere encourages putrefaction, by retarding evaporation no less than by supplying moisture. Access of Air. — That the presence of atmospheric air promotes putrefaction is shown by the slow development of gas which takes place when blood or flesh is introduced into a vessel through mercury, so as to exclude all the air which does not attach to the substance introduced : also, on the other hand, by the preservation of flesh in atmospheres not containing oxygen, such as hydrogen and nitrogen ; less completely in atmospheres in which oxygen is chemically combined with some other gas, as in carbonic acid and nitrous acid ; also in at- mospheres filled with vapours that absorb oxygen, such as turpentine. The well-known antiseptic quality of the contents of common sewers is explained partly by the exclusion of air, and partly by the presence of gases not containing oxygen. Oxygen, when taken separately, promotes putrefaction more than any other gas whatever, but when combined with nitrogen, as in atmosphei'ic air, its activity is greatly increased. It appears, then, that heat, moisture, and the free access of air, are the conditions most favourable to putrefaction. In judging, therefore, vOf the period at. which death took place, we should consider well what amount of influence each of these agents has brought to bear on the result. Period, Place, and Mode of Interment. — Period. — Bodies putrefy much more speedily in air than in the ground. Hence the longer in- 216 REAIi AND APPARENT DEATH. tennent is delayed, the greater the changes produced by putrefaction. Thus, Orfila observes, that if, during the summer, a body be kept exposed for five or six days, and then interred, it will be found, at the end of a month, to have undergone as much change as it would have . done at the end of seven months, if it had been interred at once. Site. — In dry elevated situations, putrefaction goes on slowly ; in low swampy grounds, rapidly. Soil. A dry absorbent soil retards, a moist one accelerates, putrefaction. In sand or gravel the change goes on slowly, and adipocere is rarely met with. In marl or clay, and in loose mould, especially that which is impregnated with animal or vegetable matter, moie quickly (except peat, which cleai'ly retards putrefaction). The deeper the grave, cocteris paribus^ the slower the putrefaction. The more completely the body is defended from the air by clothes or coffin, the more slowly does putrefaction go on. It is rapid where the body is exposed to the soil, but very slow where it is buried in a coffin hermetically sealed. The several media retard putrefaction in the following order : — 1. Water of common sewers and cesspools. 2. Common water. 3. The earth (in different degrees according to the character of the soil). 4. The air (in different degrees according to its temperature, moisture, &c.). Consult Orfila's * Traite des Exhumations Juridiques,' and De- vergie's ' Me'decine Legale,' which contains the marrow of Orfila's observations, with his own account of the changes produced by putre- faction in the water. The process of putrefaction as it occurs in water will have to be examined by itself Age. — Other things being equal, the bodies of children putrefy more speedily than those of adults and aged persons, and the bodies of old persons undergo this change more rapidly than those of the adult. Sex. — According to Orfila, putrefaction takes place more rapidly in females than in males. He attributes this to the greater quantity of adipose matter with which their cellular membrane is loaded. This explanation, though not quite satisfactory, agrees with the fact, that the bodies of fat persons undergo this change more readily than those of the lean and emaciated. Condition of the Body and Cause of Death. — Putrefaction takes place more or less speedily in proportion as the body is more or less filled with fluid. Accordingly, it is very rapid after sudden death, and after death from acute disease ; more slow after death from haemor- rhage, and from chronic disease, unless complicated with dropsy. After death from inhaling carbonic acid (judging from three cases mentioned by Devergie in the 17th vol. of the ' Annales d'Hygiene') putrefaction is also greatly retarded. The same observation applies to the parts of the body as to the entire frame; for those parts which are filled with fluids at the tinie of death, through inflammatign, congestion, or dropsy, or in consequence SIGNS OF DEATH. PUTREFACTION IN WATER. 217 of wounds or bruises, putrefy more rapidly than healthy and entire structures. It was formerly believed that the bodies of persons destroyed by poison putrefied very rapidly ; but it is now well known that arsenic, and the other mineral poisons, act as powerful antiseptics. Animal and vegetable poisons have probably no effect either way ; but persons poisoned by them putrefy rapidly, as in other cases of speedy death. There is reason to believe that putrefaction takes place with unusual rapidity in animals di'iven soon after a meal and dying suddenly ; as well as in men dying suddenly during violent exertion. Putrefaction in Water. — More dependence is to be placed on the criteria laid down for determining the period of death in those whose bodies have remained in the water, than in those who have been ex- posed to the air or interred, for the obvious reasons, that the tem- perature of the water is more uniform, and the body, unless when it rises to the surfece, is protected from the air. As Devergie, whose official position at the Paris Morgue has given him unusual means of observation, places much reliance on the signs by which the period of death is determined in the drowned, the following account based upon his description is subjoined. The bodies of the drowned are subject, like those who perish by other modes of death, to loss of heat and rigidity, and to putrefaction in a modified form, accompanied by the formation of adipocere. One of the first changes, which may be seen as early as the third or fourth day, consists in a bleaching of the skin of the hands. At the end of a week the body is found supple, and the skin of the palms of the hands very white. A week to twelve days of immersion bleaches the backs of the hands, and softens and bleaches the face. At the end of a fortnight the hands and feet are bleached and wrinkled, the face slightly swollen with spots of red, and the middle of the sternum has a greenish tint. At the end of a month, the hands and feet are completely bleached and wrinkled as if by a poultice, the eyelids and lips are green, the rest of the face reddish-brown, and the front of the chest presents a large patch of green with a reddish-brown spot in the centre. At the end of two months, the face is swollen and brown, and the hairs are but slightly adherent : much of the skin of the hands and feet is detached, but the nails have not separated. At two months and a half, the skin and nails of the hands are de- tached, and the skin of the feet, but the toe-nails are still adherent. In the female, reddish discolouration of the sub-cutaneous cellular tissue of the neck, of that which surrounds the trachea, and of the organs contained in the cavity of the chest ; partial saponification of the cheeks and chin ; superficial saponification of the mammae, the axillge, and the anterior part of the thighs. At three months and a half. The skin and nails of the hands and 218 SUDDEN DEATH. feet completely removed ; part of the hairy scalp, of the eyelids, and of the nose, and the skin of many parts of the body destroyed ; and the face and upper part of the neck and axillaj partially saponified. At four mouths and a half. Nearly total saponification of the fat of the face, of the neck, of the axillae, and of the anterior part of the thighs ; commencing earthy incrustation of the thighs ; incipient sa- ponification of the anterior pait of the brain ; opaline state of the greater part of the skin ; almost entire separation and destruction of the hairy scalp ; calvariura denuded and beginning to be very friable. As to the more remote periods no accurate approximations can be given ; but Devergie alleges that the above signs have been repeatedly applied with complete success to bodies that have remained in the water for periods unknown at the time of their examination. The foregoing description applies to bodies immersed during winter and spring. Bodies immersed in summer undergo the same changes much more rapidly. Thus, 5 to 8 hours of immersion in summer correspond to 3 to 5 days in winter ; 24 hours to 4 to 8 days ; 48 hours to 8 to 12 days ; 4 days to 15 days. Thus on the average the same changes in summer take place from three to five or six times as rapidly as in winter, or even more promptly than that. The changes in spring and autumn are intermediate between those of winter and summer. This account of the changes which take place in the bodies of the drowned would be incomplete without some further notice of that development of gas within the body which causes it to rise to the surface. This takes place slowly in winter, and the body rarely rises to the surface in less than six weeks or two months. But the same change takes place in summer from the 14th to the 16th day, or even earlier. In some instances the body is found to float at a much earlier period than either of those now indicated. Frequent mention has been made of adipocere. This substance derives its name from the resemblance it bears to a compound of wax and fat. It is formed by the union of the margaric and oleic acids, arising from the decomposition of the fat of the body, with the ammonia generated during decomposition. It is, therefore, a sort of animal soap. Adipocere is formed in bodies which remain for a long time in water, also in bodies buried in moist soils, and especially where a large number of bodies 'have been interred in one common grave. A body must remain about thi'ee years in the ground in order that it may be com- pletely transfoi-med, but the change takes place much more rapidly in water. In bodies which remain in the water the development of adipocere may commence as early as the third or fourth week. Adipocere is sometimes of a pure white colour, sometimes of a yellowish or brownish white. Bodies wholly converted into this substance have a ghastly bleached appearance, but retain their form, so as to admit of identification. Causes. 219 SUDDEN DEATH. Under this title it is intended to point out some of the common causes of sudden and speedy death, and to indicate those appearances in the dead body which tiirow iight on the true cause of death in the more obscure cases. That such cases are not of uncommon occurrence will be inferred from the fact that no less than from 3,500 to 4,000 sudden deaths occur year by year in England and Wales from causes not ascertained ; this number being over and above the 1 5,000 deaths returned as due to violent causes, of which the greater number also belong to the class of sudden or speedy deaths. A temporary suspension of the heart's action constitutes the chief sign and the essence of apparent death ; a total an-est of its contrac- tions is real death. Some of the vital endowments of the blood and muscles survive this cessation of the heart's action ; and the lingering imtability of the heart itself, and especially of the right auricle, forms our ground of hope in the use of means of resuscitation. This suspen- sion or total arrest of the heart's action, or, in other words, apparent or real death, may be brought about by different causes, of which some act directly on the heart, and others indirectly through the medium of the lungs. The causes of sudden death which act directly on the heart are either — I. Structural diseases of the heart itself, and of the large vessels, or 2, Nervous shocks paralyzing its muscles, or 3, Causes cutting ofiF the supply of blood to it, or 4, Causes destroying the stimulant property of the blood. 1. The structural diseases of the heart and large vessels, such as disease of the valves, hypertrophy, aneurism of the aorta, and ossifica- tion of the heart, aorta, or coronary arteries, are readily discovered on post-mortem examination. The only diseases of the heart which might escape observation are atrophy and fatty degeneration of the muscular tissue ; and there is reason to believe that both of these causes are occasionally overlooked. In some instances, as in two cases related by Mr. Paget, death really due to fatty degeneration was believed to have been caused by poison. 2. The nervous shocks of sufficient force to paralyze the heart, and to cause instant or speedy death, may be caused by strong and sudden emotions of fear and joy, by the lightning and sun-strokes, by heavy blows on the head or pit of the stomach, by violent exertion giving rise to sudden effusion of blood on the brain (of which one case has come under the notice of the author), by large drafts of cold water swallowed when the body is heated, and by a few of the more active poisons given in full doses. 3. The supply of blood necessary for the heart's action may be cut off by profuse haemorrhage. It may also be kept from the left side of the heart by the arrest of the circulation through the lungs in death by apnoea. But this belongs to the class of indirect causes. 220 SUDDEN DEATH. 4. The proper constitution of the blood may be destroyed by the mechanical admixture of air introduced into the veins during opera- tions on the neck, shoulder, or axilla ; or it may be chemically de- stroyed by poisons, directly introduced into the circulation. This contamination of the blood plays an important part in death by all the more active and deadly poisons, whether inhaled or swallowed. Of the causes of sudden or speedy death which act indirectly upon the heart, the most common is that an-est of the circulation through the lungs which attends the several forms of sufi'ocation. A similar arrest of the pulmonary circulation constitutes the intermediate link between the less severe shocks to the nervous system and the ultimate arrest of the heart's action. Seveial of the foregoing causes of sudden death are at once revealed by a careful inspection of the body ; but those causes of death which do not leave behind them any structural change may yet give rise to such marked changes in the distribution of the blood through the body, and in and about the heart, as to aid us very materially in our inquiries into the true cause of death. Thus, death from the rapid loss of blood would be indicated by pallor of the surface, and the empty and con- tracted state of all the cavities of the heart ; death from shock sud- denly arresting the circulation, by a distended state of all the cavities of the heart; and death from suffocation by violet patches on the surface of the body, and distension of the right side of the heart with dark blood. The causes of sudden death, and the post-mortem appearances by which they are indicated, may be more fully discussed by adopting the well-known classification of Bichat ; namely, death beginning at the head, death beginning at the heart, and death beginning at the lungs. Sudden Death commencing at the Heart. — Syncope. — The phe- nomena which attend this form of death are : — Pallor of the face and lips, cold sweats, dizziness, dimness of vision, dilated pupils, gasping and sighing respiration, a slow, weak, and irregular pulse ; to which are sometimes added nausea and vomiting, restlessness and tossing of the limbs, transient delirium and convulsions. On inspecting the body, the vessels generally are found to contain but little blood, and the heart to he nearly or quite empty, and contracted. This empty state of all the cavities of the heart contrasts strongly with their distended state in the rare cases of death originating in the brain, and acting directly upon the heart; and not less strongly with the distended condition of the right side of the heart, and empty state of the left, which occurs in death commencing in the lungs. Sudden Death commencing at the Head. — Injuries to the nervous centres may act directly upon the heart, and put a stop to its contrac- tions : or they may first afi'ect the fimction of respiration by paralyzing the respiratory muscles. When the heart is directly affected, the BEGINNING AT THE LUNGS. APN(EA. 221 circulation is, as it were, arrested and fixed in what may be termed its normal state, each side of the heart containing its due proportion of blood, and all the cavities being distended from the sudden loss of power in the heart to propel its contents. This mode of death has been designated asthenia. When, on the contrary, the muscles of respiration are paralyzed, the post-mortem appearances will be those presently to be described under the head of apnoea. Sudden Death commencing at the Lungs : Apnoea {Asphyxia^. — The sense now affixed to the term asphyxia departs strangely from the original derivation of the word, which means pulselessness. It is now understood to mean real or apparent death due to a suspension of the function of respiration, — a mode of death much more aptly designated by the term apnoea. Apnoea may be produced by a great variety of causes, of which the chief are : — 1. Cessation of the action of the muscles of Respiration, 2. Cessa- tion of the action of the Lungs themselves. 3. Exclusion of the atmo- spheric air from the Limgs. 1 . Cessation of the Action of the Muscles of Respiration may be due to inertia of the muscles themselves, in consequence of cold or debility ; to a loss of nervous influence supplied to the muscles, as fi'om division of the upper portion of the spinal marrow, or of the pneumogastric and phrenic nerves, from the lightning stroke and from apoplectic seizures ; to mechanical restraint, as by pressure on the chest or abdomen ; or to tonic spasm, as in death from Tetanus or Hydrophobia. 2. Cessation of the Action of the Lungs. — This may be due to a division of the eighth pair of nerves ; or to a mechanical obstacle, such as the admission of air into the pleura, or the entrance of the viscera of the abdomen through a wound in the diaphragm. 3. The partial or complete Exclusion of Atmospheric Air from the Lungs may be brouglit about by the entire absence of air, as in a vacuum ; or by its extreme rarefaction, as on the top of very lofty mountains. The air, again, may be mechanically excluded, as by a foreign body introduced into the larynx, by submersion, by suffocation, by strangulation, by suspension. Or lastly, the place of the atmo- spheric air may be taken by a gas, such as nitrogen or hydrogen, which cannot support respiration. Other gases seem to exercise a deleterious influence on the economy, independent of the mere exclusion of the air. Some of these are intensely irritating, as the sulphurous acid gas, chlorine, and ammonia ; others, though less irritating, are not less fatal in their effects, such as the carbonic acid, carbonic oxide, car- buretted hydrogen, nitrous acid, hydrosulphuric acid, hydrosulphate of ammonia, arseniuretted hydrogen, and the vapour of hydrocyanic acid. Some of these, as well as the more simply irritant gases, may act mechanically by producing a spasm of the glottis, and closing it against the admission of air. To this list of the causes of apnoea may be added certain diseases of 222 SUDDEN DEATH. the lungs, as hepatization, oedema, or tubercular infiltration, which prove fatal by filling the air-cells, and preventing the process of re- spiration from being duly performed. The symptoms of apnoea will be more or less strongly marked accord- ing as the asphyxiating cause acts suddenly or slowly. If the at- mospheric air is suddenly excluded from the lungs, as by mechanical compression of the trachea, complete submersion, or the inhalation of a gas which is so irritating as to cause spasmodic contraction of the glottis, the symptoms are strongly marked, and run a rapid course. The sufferer struggles violently for breath, and uses strong efforts to remove the obstruction. The face at first flushes, but soon grows turgid and livid ; the veins of the head and neck swell ; the eyeballs start from their sockets ; and the swollen tongue protrudes between the teeth. A short attack of giddiness, with bright spots before the eyes, and ringing sounds in the eais, is followed by loss of conscious-, ness, convulsive movements of the limbs, and relaxation of the sphincters, with expulsion of the urine and faeces and more generally of the prostatic fluid. In two or three minutes, if relief be not afforded, life is extinct. When the asphyxiating cause acts more slowly, the symptoms are somewhat modified, and succeed each other at longer intervals. There is a feeling of constriction in the chest, from which the sufferer strives to free himself by strong voluntary efforts to inspire air, or by the involuntary efforts of yawning or sighing. A dull heavy pain in the head, especially over the forehead, with giddiness, dimness of sight, and torpor of the intellectual faculties succeed, and gradual loss of sensation and voluntary motion. Still, the functions of re- spiration and circulation continue, as shown by almost imperceptible movements of the walls of the chest, and pulsations of the heart scarcely sensible to the hand. This imperfect state of respiration and circulation is followed by the entire cessation of those functions, and by complete loss of motion, voluntary and involuntary. At this point of time the fulness of the capillary system begins to show itself, by the injected state of the face, and by a deep violet discolouration of that part, which also extends to the hands and feet. Some portions of the trunk and extremities exhibit spots, more or less extensive, of the same colour. At length, the capillary circulation ceases, and the state of apnoea is complete. In some cases the asphyxiating cause, acting more slowly still, seems to induce a sleep which terminates, without suffering, in death ; in other instances, the sensations are even pleasurable, consisting of a display of beautiful colours or of pleasant landscapes before the eyes. There is still another class of cases in which the sufferer, suddenly roused from a state of torpor to a vivid and painful per- ception of his state, makes an effort to escape from the death which threatens him, but finds his muscular strength unequal to the accom- plishment of his purpose, and falls to the ground. THEORY OF APNCEA. 223 After death the body presents the following appearances : — Patches of rosy, bright red, or violet, discolouration are seen on the face or on other parts of the body, as much on the least as on the most depending parts. The eyes are usually prominent, firm, and brilliant. The mouth is sometimes expressive of calmness, at others of suffering. Cadaveric rigidity is very marked, and continues for a long time. The venous system of the brain is commonly full of blood, but its substance presents, when divided, but few bloody points. Sometimes the ventricles of the brain contain serum ; sometimes blood is effused at the base in the substance or on the surface of the organ. The base of the tongue is almost always injected, and its papillae strongly developed. The lining membrane of the epiglottis, larynx, and trachea, is of a deep red colour, and the colour increases in intensity as we approach the last ramifications of the air-tubes. The air-pas- sages often contain a frothy sanguinolent fluid. The lungs are so much distended and increased in size as to project over and conceal the pericardium. They are of a deep violet colour, and when cut into and compressed, large drops of black, thick, liquid blood exude. The liver, the spleen, and the kidneys, are also gorged with blood. The veins of the heart are distinctly traced upon its surface, its right cavities and the large venous trunks are gorged with black, thick, liquid blood ; but the left cavities of the heart are found nearly or quite empty. Such are the appearances present in death by apnoea when it occurs in its unmixed form : and they are those observed in the bodies of persons who have perished by inhaling carbonic acid. But all these appearances aie not present in every case, nor, if present, are they equally marked in all. Theory of Apnasa {Asphyxia). — When air is prevented from gaining access to the lungs, the blood does not undergo its usual change from venous to arterial, and venous blood does not minister to the support of the vital functions of the several organs so completely as the arterial blood does. Some, indeed, have supposed that venous blood is a positive poison ; and that it is much worse for an organ to be supplied exclusively with venous blood than to receive no blood at all. On this assumption, the cessation of the heart's action may be ex- plained in one of three ways. The heart may be paralyzed by the circulation of the venous blood through the coronary arteries in place of arterial blood ; or the venous blood may be unfitted to excite the left cavities of the heart to contraction ; or, again, the nervous in- fluence supplied to the heart from the nervous centres may be sust- pended by the circulation of venous blood through the nervous tissue. But the assumption that venous blood is directly poisonous, and worse than no blood at all, has been disproved, as far as it can be, by experiment. Kay has shown that the venous blood exercises no dele- terious influence on the muscles, by comparing the contractility of a 224 SUDDEN DEATH. limb from which the supply of arterial blood has been cut off with that of a limb supplied exclusively with venous blood ; and Edwards found that a cold-blooded animal placed in an asphyxiating medium lives longer than one whose heart and bulb of the aorta have b^en excised. Venous blood, therefore, is not positively, or to a great degree, in- jurious ; its circulation is merely a negative injury, and destructive of life by occupying the place of arterial blood and cutting off the supply of that fluid to the economy. As the absence of all circulation through the vessels of the heart, or through those of the brain, or through the nerves supplying the heart with vital stimulus, would certainly and speedily prove fatal to life, so would the mechanical exclusion of ar- terial blood from the vessels of those parts, whether by warm water or by venous blood. This theory of exclusion, then, is adequate to the explanation of death by apncea. It has been shown, however, by Dr. Kay, that neither this theory, nor the theory of poisoning by a deteriorated blood, is the true one ; but that the essential character of this form of death consists in the accumulation of blood in the lungs and right cavities of the heart, and a diminished supply of that fluid to its left cavities ; so that the quantity of blood sent out for the supply of the system constantly diminishes, till at length the circulation is altogether arrested. Hence in death by asphyxia the left ventricle is found contracted, and nearly or altogether empty. It is of little consequence to inquire into the proximate cause of this arrest of the circulation through the lungs ; the fact is all with which, as medical jurists, we have to do. On contrasting the post-mortem appearances proper to the thi-ee modes of death, syncope, asthenia, and apnrea (asphyxia), it will be seen, that in the flrst, all the cavities of the heart are empty or contain little blood ; in the second, all the cavities are full of blood ; and in the third, the right side is gorged with blood, while the left ventricle contains little or none. It is most important, however, that the medical jurist should bear in mind that the characteristic ai)pearances of sudden death, due pii- marily to the heart, the lungs, or the brain, are not always equally marked ; that they may be combined with each other in difierent pro- portions ; and that a cause usually productive of the one may, in certain circumstances, give rise to the other. Thus, a person may be threatened with suffocation (one of the causes of apnoea), and appre- hension may give rise to sudden syncope ; or a violent attempt to escape the threatened injury may burst a blood-vessel in the brain, and cause apoplexy. We must, therefore, bear m mind the possibility of such combinations as these, in order that we may be prepared to understand the different appearances presented by those who perish from a common cause. It may be useful to subjoin the following facts connected with sudden death. RELATIVE FREQUENCY OF ITS DIFFERENT FORMS. 225 From the 19th Annual Report of the Registrar-General, it appears that of 416,470 deaths from all causes, occurring in England and Wales, on the average of the five years 1852-56, 13,711, or about 1 in 30, were violent deaths, of which 3045 were due to various fonns of chemical injury, 3826 to apnoea (asphyxia), and the remaining 6840 to various mechanical injuries. Of the 13,711 violent deaths, 10,057 occurred in males, and 3654 in females. The sudden deaths, for the average of the same five years, are stated at 3843 or more than 1 per cent. (1 in 109). They are distributed between males and females in the proportion of about 3 to 2. The suicides on the average of the same five years amounted to 1083, of which 777 in men and 306 in women. Of 1044 due to ascertained causes, 642 were brought about by various forms of suffo- cation, 111 by poison, 1 by burning, and the remainder by mechanical injuries, among which 210 cut throats, 43 gun-shot wounds, 12 other wounds, and 20 falls. The suicides by poison by men and women respectively were as 6 to 5, by apncea as about 3 to 1, and by me- chanical injuries at about 4 to 1. The greatest number of suicides in both sexes occtfrred between the ages of 45 and 55. The relative fre- quency of the several forms of sudden death appears, from a work of Ferrario and Sormoni on sudden deaths occurring in Milan, to be as follows :■ — Head (including apoplexy, cerebral con- cussion, vertigo, and coma) . . 879 or about 4 in 5. Heart (including diseases of the heart, angina pectoris, aneurism, and haa- morrhage). .... 150 or about 1 in 7. Lungs (including asphyxia, suffocative catarrh, and pulmonary apoplexy) . 14 or about 1 in 75. Difficult labours .... 5 Total . . . 1048 The relative frequency of the different forms of sudden death classi- fied according to their proximate causes must, however, be understood to differ at different periods of life. The proportions just stated are ob- viously those which obtain chiefly among adults ; for sudden deaths in infancy and childhood, if classed according to their causes, would re- verse the order just stated. By ftir the most common cause of death in infancy and childhood is to be found in the lungs, and the least common in the brain, though the fact of convulsions being verv common in early life might lead a superficial observer to attribute the majority of sudden deaths to the brain and not to the lungs. The diseases of the lungs which give rise to sudden or speedy death in infants and young children are spasmodic croup or laryngismus stridulus, to which Dr. West attributes three out of four of the sudden Q 226 suiivivousHiP. deaths of children under one year old, imperfect expansion of the lungs at bii-th (atelectasis pulmonum), sudden collapse of the lung, consolida- tion from pneumonia, and sudden serous effusion into the pleura, to which ought to be added a disease not mentioned by Dr. West in the paper now referred to, pulmonary apoplexy. A not uncommon cause of sudden death among the children of the poor is suffocation, as a con- sequence of drinking hot water from the spout of the kettle. Next to diseases of the lungos, sudden death by exhaustion from insufficient food, or chronic diarrhoea, is most common, while fatal disorders of the brain are very rarely to be set down among the causes of sudden death in infancy and childhood. Of the sudden deaths entered in the tables of the Registrar- General upwards of one-third occur in infancy.* SURVIVORSHIP. When two or more persons die by the same accident, a question sometimes arises as to which died first ; for, in certain cases, the succes- sion to property would be secured on proof of survivorship even for an instant of time. Hitherto little has been done towards establishing broad general principles applicable to this class of inquiries : indeed, the materials for the establishment of such principles are wanting. Some of the more accurate results which have been attained will be found stated in the following pages under the following heads: — 1. Of the probabilities afforded by age and sex, irresi>ective of the mode of death. 2. Of the degree in which such probability is atTected by the peculiar mode of death. 1. Of the Probabilities afforded by Age and Sex. Age. — As the body attains its full growth and strength at about 27 years of age, or from 25 to 30, and, in healthy persons, continues strong and vigorous up to about 50, there will be no sufficient ground for inferring survivorship in the case of adults of the same sex, whose ages range between 25 and 45, or even betwe.en 20 and 50, provided the form of death is one in which mere strength of frame and power of endurance is concerned. Before and after the ages specified, the strength and power of endurance will be less, but still within the limits of puberty and old age (say 15 and 60 years) the difference will probably be inconsiderable. The probability of survivorship, in the case of a middle-aged adult perishing with one under puberty or above 60, will be in favour of the adult. In the case of one under 15 and one above 60 perishing together, the French law assumes that the former survived : when both are under 15, that the elder outlived the younger. According to the civil law of England, if parent and * See a Lecture by Dr. West, on Sudden Death in Infancy and Childhood in tlie 'Medical Times and Gazette/ Nov. 26, 1859. PROBABILITIES ESTABLISHED BY THE MODE OF DEATH. 227 child perish by a common death, the child shall be presumed to have survived if above puberty, and' to have died first if under puberty. In the case of a mother and child both dying in childbed, without assistance, the presumption is, that the mother survived, for there is a chance of still birth, and a further probability that the child, if bom alive, would die before the mother would be able to render the assist- ance necessary for its preservation. A large child would be still move likely to perish first, for it has been elsewhere stated (p. 84) that still- born children greatly exceed in size and weight those born alive. If the body of the child could be examined the presumption might be still further strengthened by the external marks of a difficult labour, or the absence of the signs of respiration. Legal decisions have not been always in conformity with the principle here laid down. Sex. — If one of either sex perish by a common accident, it may be inferred that the male, being the stronger, is the survivor ; but this rule applies only to modes of death in which strength and courage give the best chance of safety. On the other hand, females being subject to prolonged fainting in consequence of fright, may be, by that very circumstance, incapacited from those struggles which in so many foi-ms of death may be presumed to increase danger. When, then, there is safety in exertion, the probability of survivorship will be with the male ; where passive endurance or insensibility would tend to lessen the danger, with the female. 2. Of the Degree in which the foregoing Probabilities are affected by the Mode of Death. Under this head it is proposed -to specify some of the more common modes of death, and to endeavour to establish some general principles with respect to them, assuming, as before, that the parties about whom the question is raised are placed, as nearly as may be, in the same circumstances. Apncea {Asphyxia). — Women consume less oxygen than men ; the same quantity of air, therefore, will last them for a longer time. Hence, of adult males and females perishing together of apncea, the females may be presumed to have survived. In poisoning by carbonic acid gas, which is nearly allied to death by apnoea, the chances of survivorship are with the female. This statement rests on the authority of a large number of facts. In 19 out of 360 cases of poisoning by carbonic acid, which took place in Paris during 1834 and 1835, a man and woman were exposed to the fumes of charcoal together : of these three only were saved, and these three were females. In solitary cases of the same form of death the result is also favourable to the female ; for 1 8 out of 73 females were restored, and only 19 out of 83 males, so that the chances for the female and male respectively are nearly as 15 and 14 (instead of 5 and 4 as Devergie represents it). Single cases are in strict conformity 228 SURVIVORSHIP. with this result. Thus, in a case quoted by Beck from the 'Transyl- vania Journal/ a man and his wife were exposed in a small room to the gas from live coals. The man was found dead, rigid, and con- tracted, but the woman was still breathing and recovered. Again, in a case reported by M. Sardaillon, a man, his wife, and their child aged seven years were asphyxiated in a porter's lodge. The child died, the father was very ill and with difficulty restored to life, while the wife was well enough to call for help and to assist both husband and child. In these cases it would be necessary to take into account the position which the parties occupied in the room, whether on the bed or on the floor, near to or remote from an open window, &c. Drowning. — There are many complicated considerations connected with this mode of death. In shipwrecks men are more likely to be in a favom-able situation for saving themselves, as they are more on deck than women ; they also in many instances are able to swim , or to save themselves by clinging to portions of the wreck, and they are less encumbered by clothing. When the comparison is between men similarly exposed and capable of the same exertion, it may be necessaiy to inquire whether one was more exposed to cold by having the body half immersed, while the other was more under water. Search should also be made for severe injuries which may have prevented the swimmer from using his strength, or may have otherwise proved fatal. Apoplexy is stated by Devergie to be sooner fatal than apncea, while in death by syncope there is the best chance of recovery. Suffocation. — In all cases of suffocation depending upon an insuffi- cient quantity of air, or upon air rendered partially unfit for respira- tion, it may be presumed that those who require least air live the longest — women longer than men, children than adults. In suffocation from the falling of houses or earth, or by mechanical means in general, the stronger may be presumed to survive the weaker — men, women ; adults, children and old persons. Cold. — As young children bear cold worse than adults, the pro- bability of survivorship in exposure to the same degree of cold is in favour of the latter. Men bear cold better than women, adults better than the aged. It is necessary also to take into account the clothing of the persons exposed, and their state of health. Spirituous liquors in excess increase the effect of cold ; in moderation they give increased to- lerance of it. Heat. — The young and old, as they suffer more from cold, so do they bear heat better. " The relative tolerance of heat of the two sexes is not well ascertained. Fodere relates the case of an Englishman and his daughter aged seven years, who, in the year 1814, crossed the desert of Syria to the Persian Gulf. Both rode on camels, and were placed in precisely similar circumstances, but the father died, while the child arrived in safety at its journey's end. Hunger and Thirst. — Those who have not reached their full growth require more nourishment than adults, and adults more than aged HUNGER AND THIRST. 229 persons. The aged, then, if healthy and robust, may be presumed to survive both, and the adult to live longer than the child. Corpulent persons are thought to bear hunger better than the emaciated. In death from starvation, those who have the freest access to water may be presumed to live the longest. Those who use the greatest exertions will suffer earliest in this as in the foregoing modes of death. Those who possess most passive endurance may be expected to live the longest. Such are some of the principal forms of death, in which the circum- stances of the several victims are likely to be so similar as to admit of the application of general rules. In other modes of death, and in these under certain circumstances, there may be no points admitting of strict comparison, and many things which may exercise a marked influence on the result will have to be taken into the account. The reader will find several such cases quoted in Beck's ' Medical Juris- prudence ;' but as they throw little light upon the general question, and establish no fixed principles, it would be useless to quote them. It has been suggested by more than one writer, that a distinct enactment would be preferable to the present custom of deciding each case on its own merits. Such an enactment, extending to that large class of cases in which the circumstances of the death are but im- perfectly known, and to those in which it is in the very nature of things impossible to come to a correct decision, is certainly much to be de- sired. On many points, as it has been seen, the opinions of medical men can throw much light, and their researches lead to general princi- ples admitting of tolerably safe application. 230 CHAPTER II. DROWNING HANGING — STRANGULATION— SUFFOCATION. These modes of death are brought together in the same chapter, as they are all forms of apnoea, or sudden death beginning at the lungs. DEATH BY DROWNING. The medico-legal importance of this cause of death may be inferred from the fact, that on an average of the five years 1852-56, 2352 deaths were caused by drowning, of which 1847 in males and 505 in females. Of this number 164 (87 males and 77 females) were ascer- tained acts of suicide. Although death by drowning is commonly attributed to apnoea, it is not always due to that cause. Hence this subject is not so simple as at first sight it would appear to be. To make it intelligible it will be necessary to describe the various modes in which a man found in the water may liave come by his death, supposing him to have died in the water. When a man in perfect possession of all his faculties falls into the water, he sinks to a greater or less depth, but immediately rises to the surface again ; and, if he is a swimmer, makes efforts to save him- self, till at length he is reduced to the condition of one who cannot swim at all ; with this difference, that he has already exhausted the strength which the other has in reserve for the death-struggles common to both. These struggles consist of irregular movements of the arms and legs, and graspings of the hand at all objects within reach, whether floating in the water, fixed at the bottom of it, or gi-owingon the banks. In the course of these irregular movements he rises repeatedly to the surface, tries to breathe, and takes in air and water. The contact of the water with the windpipe causes a cougl^ by which part of the fluid is rejected, antl with it some of the air contained in the lungs. This occurs again and again, till the body no longer rises to the surface ; water alone is received in the vain efl'orts to respire, while forcible involuntary expirations continue to expel the air from the lungs. At length all these efforts cease, the body sinks to the bottom of the water, and bubbles of air are forced from the chest by the elastic reaction of its parietes. The greater part of the water which has been taken in finds its way iuto the stomach, and a smaller portion into the lungs ; and this portion, mixed with the DIFFERENT FORMS OF DEATH BY DROWNIKG. 231 secretions of the mouth and air-passages, and frothed by the air in- spired and expired, forms the foam so constantly met with in persons who have perished in this way. In cases belonging to the class just described, we may expect to find the a})pearances proper to death by apncea, coupled with those due to the medium in which the death takes place. In the case of the swim- mer death may take place from exhaustion, with only indistinct signs of death by suH'ccatiou. But death may take place in the water, and yet be caused neither by apnoea nor by exhaustion. There may be a complete loss of con- sciousness at the very moment of immersion. This may happen from fright, from drunkenness, from an attack of hysteria, or of catalepsy (of which latter the author has known one melancholy instance) ; and in this case the body falls to the bottom of the water, rises again to a certain height, and sinks without a struggle. In these cases death is due to shock, or to syncope, and not to suffocation. Again, a person may fall or throw himself into the water with the head foremost, and, striking against a rock or fragment of wood, or even against the surface of the water itself, perish by concussion ; or the body falling or thiown from a height may strike the water w\th the chest and pit of the stomach, so as to cause instant death from shock. In these cases, also, death is due to causes other than apnoea. Again, cold, excitement, or the first violent struggles, may occasion apoplexy, or sudden death from disease of the heart. These sudden deaths by diseases of the brain and heart are of occasional occurrence in persons bathing in cold shallow water. Death by drowning may also be of a mixed character. A man falls into the water in the full possession of all his faculties ; he preserves them for a time, till, struck with horror at the death which threatens him, he faints, and thus perishes. It appears, then, that death by drowning may be due to apnoea, to exhaustion, to shock or syncope, and to apoplexy ; and, further, that death may be brought about partly by apnoea and partly by one of the other causes now specified. The cases in which marks of apnoea more or less distinct are found in the body, either separately or blended with those proper to some other form of death, fo]-m the great majority, and cases in which the signs of apncea are wholly absent a small minority, while cases of pure and rmmixcd apnoea occupy an intermediate place. Devergie, whose opportunities of experience in this class of cases have been already alluded to, estimates the cases of unmixed apncea as one in four or two in eight of the whole, the cases in which no traces of apnoea exist as one in eight of the whole, and the mixed cases as five-eighths of the whole. The appearances present in the body of the drowned must of neces- sity vary with the manner and precise cause of death. In those cases in which death has been due to apnoea, the post- moitem appearances will be those proper to that mode of death 232 DEATH BY DROWNING. (see p. 223), but blended with those due to the medium in which the death happened, and modified by the time that the body has remained in the water, as well as by the period of exposure to the air after removal from the water. Supposing the death to have been due to apnoea, and the examina- tion of the body to be made soon after the death and removal from the water, it may be expected to present the following appearances : — The face and general surface of the body are either pale or slightly livid, with occasional patches of a deeper tint. The expression of the face is generally calm. The tongue is swollen, and closely applied to the teeth, rarely protruded between the closed jaws, and still more rarely wounded and bloody ; and there is a frothy foam at the mouth. The air-passages also contain a froth, which is sometimes tinged with blood ; and the trachea and larger bronchial tubes contain water which sometimes penetrates to their most minute ramifications. Some- times the water is in such quantity as to fill the whole of the air- passages, and it occasionally carries with it portions of slime or mud, or fragments of aquatic plants. The lining membrane of the air-passages is sometimes found con- gested ; the lungs contain a large quantity of black fluid blood ; the vena; cavai and right cavities of the heart are distended with dark blood, while the left cavities and aorta are comparatively empty. The stomach almost always contains water, of which the quantity is some- times very considerable. The intestines have a rosy colour ; the liver, spleen, and kidneys are gorged with blood ; and the bladder sometimes contains urine tinged with blood. The brain piesents the same ap- pearances as in other cases of death by apnoea. Sand or mud are often tound in the hollow of the nails, the fingers are sometimes abraded, and portions of plants growing in the water, or on the banks of the stream, are sometimes found grasped in the hands. Injuries received in falling into the water during the death-struggles, or through the violence of the stream, may also leave their marks upon the body. These will presently be more minutely described. In bodies which have remained in the water, or been exposed to the air for some time, the pallid, or slightly livid hue of the features just described may be exchanged for a bloated appearance, and large livid spots may show themselves on different parts of the body, as in other cases of death by apucea. In death by shock, syncope, or exhaustion, there is little or no water in the air-passages or in the stomach. The cavities of the heart and large vessels are equally distended with blood, or are nearly empty, and the brain and internal viscera are in their natural state. Death by concussion or by apoplexy, or by disease of the heart, will reveal itself by the usual post-mortem appearances. In mixed cases the post-moi-tem appearances due to apnoea will be less strongly marked. There will be less froth at the mouth, less water and froth in the air-passages, and in the stomach ; and less WAS DEATH CAUSED BY DROWNING? 233 congestion of the lungs, of the heart and great vessels, and of the internal viscera. Several medico-legal questions suggest theniselves in reference to a body found in the water, of which the first in order is the following : — Was death caused by drowning i In the case of a ' person found dead in the water, the death may obviously have happened from natural causes or from intentional violence prior to the immersion ; and in the latter case the death may have been due to some cause producing apncea, and giving rise to the characteristic appearances proper to that mode of death. In other words, a person may be strangled or suffocated, and then thrown into the water to conceal the true cause of death. In forming a decision on a question of so much difficulty, we shall have to consider the several post-mortem appearances alleged to be characteristic of death by drowning, and to determine whether they might have been occasioned by causes acting before immersion. We must also determine whether, in the case of bodies remaining in the water some time after death, the appearances usually attributed to the mode of death may not be explained by the peculiar circum- stances in which the body is placed. Of the post-mortem appearances present in bodies found in the water, some are common to death by drowning and to death by other forms of apnoea, while others are peculiar to death by drowning. To the first class belong the position and swollen state of the tongue ; the pallor with rosy or violet discolorations of certain parts of the skin ; the injected state of the brain ; the congestion of the internal viscera ; the fulness of the right cavities of the heart, and emptiness of the left ; the fluid state of the blood ; and the existence of bloody urine in the bladder. To the second class belong : — excoriations of the fingers, with sand or mud in the hollow of the nails ; fragments of plants grasped in the hand ; water in the stomach ; froth at the mouth and nostrils ; and froth, water, mud, or sand in the air-passages. Of the post-mortem appearances belonging to the first class, it will suffice to observe, that their presence in persons found dead in the water is consistent with the supposition of death by drowning, but that they might have been caused prior to immersion by any of the modes of death which act by occasioning apncea. If the body is free from marks of strangulation, death might still have been caused by suifocation produced by forcible closure of the mouth and nostrils. The post-mortem appearances alleged to be due to drowning, and to be characteristic of that mode of death, must now be briefly con- sidered. Excoriations of the Fingers are much more frequently absent than present ; but, when they exist, may be regarded as a probable, though not certain sign of death by drowning. They might be caused previous to forcible immersion, by the rubbing of the fingers against any hard and rough body ; and possibly after death in running streams. Sand or mud in the hollows of the nails, also, affords a probability 234 DEATH BY DROWNING. of immersion during life, inasmuch as it implies, like the excoriations of the fingers, that the drowning man grasps at the bed or banks. But if the body remained long in the water, mud or sand might be deposited in the hollow of the nails. If the hands were found clenched and grasping weeds growing in the stream or upon the banks, there would be the strongest probability in favour of death by drowning. Water in the Stomach. — The discoveiy of water in the stomach affords another strong presumption in favour of death by drowning ; especially if the water can be identified with that in which the body was found by its containing leaves of plants growing on the banks or at the bottom. Except in the cases presently to be mentioned, it presup- poses acts of deglutition during efforts to breathe. It must, however, be admitted to be possible, though very unlikely, that the water might have been swallowed a very short time before submersion. The quantity of water found in the stomach is very variable ; and depends partly upon the number of efforts at respiration made during the act of diowning, and partly on the depth of the water. In animals that have been stunned befoi'e immersion, as well as in animals kept under water from the first, and prevented from rising to the surface, the stomach contains no water ; while in animals allowed to rise to the surface, it is found to be in proportion to the number of times that the animals so rise. That the depth of the water also influences the quantity found in the stomach is proved by the experiments of Dr. A. Taylor. The stomach of a cat held two feet below the su?face of the Thames contained scarcely any water ; but that of a cat lowered to the depth of fifty-five feet con- tained a large quantity. The stomach of a third cat which was allowed to rise repeatedly to the surface of the water, was distended, but not so much as the one which had been lowered to the depth of fifty-five feet. The influence of the columnar pressure of the water is, therefore, considerable ; and it is probable, that where the water is very deep the pressure of the fluid may overcome the resistance offered by the collapse of the oesophagus, even though the animal died previously to submersion. It appeai-s, moreover, that water may enter the stomach in consequence of putrefaction producing a general relaxation of the tissues. From what has just been stated, it is obvious that the discovery of water in the stomach is not tn be considered as conclusive evidence of death by drowning, when the water is of great depth, or when the body is far advanced in putrefaction. It must also be admitted to be possible that the water might have been swallowed immediately pre- viously to immersion, and possible, also, though most improbable, that it might, as suggested by Orfila, be maliciously injected after death. But though the discovery of water in the stomach affords a pre- sumption of death by drowning, its absence must not be taken as evl- SIGNS OF DEATH BY DROWNING. 235 dence to the contrary ; for it is not present in cases of death by drown- ing due to causes other than apnoea, such as shock, syncope, concussion, or apoplexy. The tendency to swallow may also be voluntarily re- sisted ; or the body may be, in some way or other, prevented from rising to the surface. On the other hand, water may have entered the stomach, and yet not be found there after death ; for if the head be allowed to hang below the rest of the body, the water will flow from the stomach. This fact also has been proved by Dr. Taylor's experiments. If, more- over, the body is long exposed after its removal from the water, the fluid contained in the stomach may transude through its coats, and disappear. The absence of water from the stomach, therefore, is not conclusive against death by drowning, for it may have gained access to the stomach, and subsequently disappeared ; or it may never have entered the stomach at all. Froth, water, mud, or sand, in the Air-Passages. — Mucous froth. — The experiments of Piorry and Orfila have clearly shown that the presence of mucous froth in the air-passages is due to the body rising repeatedly to the surface for air, and that it does not exist in animals kept entirely under water. This froth is also absent when the body remains in the water a long time after death, or is subject to long exposure after its removal from the water, or when the head is placed below the level of the body. The value of this mucous froth as evidence of death by drowning is also impaired by the fact that it exists not only in the several forms of death by apnoea, but in death by apoplexy or epilepsy, and in catarrhal and other affections of the lungs. Water in the lungs. — That water generally enters the lungs in death by drowning has been abundantly proved by experiments on animals, and by cases in the human subject in which not water only, but sand and mud, have entered the air-passages. By drowning rats in chalk and water, with free access to the air, I have never failed to obtain effervescence by means of acids in every part of the lungs. But the value of this sign is impaired by the fact that water may enter the lungs of those who have been thrown into the water after death. Orfila and Piorry found, that the quantity which thus gained admission to the lungs, varied according to the position of the body. When it remained upright there vfas, a large quantity; less when horizontal. It has been suggested that water may be injected after death. This is most improbable. But water is not always present in the lungs of those who have died by drowning ; for, as in the case of the stomach, if the head is left depending, the water flows out. Long exposure, too, will cause it to transude and be lost. Froth at the Mouth and Nostrils. — This, too, is a sign of death by drowning ; but it is open to all the objections just stated in respect of 236 DEATH BY DROWNING. froth in the air-passages. It depends, indeed, very closely on the existence of froth in the air-passages, as well as on the development of the putrefactive process, and the consequent generation of gas forcing the froth in the larynx and trachea into the fauces. Hence it is more frequently present in summer than in winter. From this examination of the signs of death by drowning, it appears that there is no single sign on which entire reliance can be placed. When, however, several signs happen to coincide, the probability is greatly strengthened. Like the symptoms of disease, they may be of little value when taken separately, but when combined they enable us to form a safe diagnosis. Some authors, and Orfila among the number, have, indeed, thought that the question,^ Was death due to drowning? admits of no decision ; but from this o'pinion Devergie very properly dissents. It is important to bear in mind, that the appearances characteristic of death by drowning are not permanent. In winter they may con- tinue after the body has lain from fifteen to eighteen days in the water, while in summer they would disappear from the third to the sixth or eighth day of immersion. The exposure of the body to the air also causes them rapidly to disappear, and in che height of summer a few hours would suffice to dissipate them. When putre- faction has gone to any considerable extent, all the signs of death by drowning are of course completely removed. The time that the body has remained in the water will be deter- mined approximately by the signs laid down at page 217. The evidence derived from the signs of death by drowning already discussed admits of being confirmed or invalidated by the condition of the body in other respects, especially by the presence or absence of Marks of Violence. — With regard to injuries discovered on the bodies of persons found in the water, three questions arise : — 1 . Were they inflicted during life ? 2. If inflicted during life, are they of such a nature as to account for death before submersion ? 3. Were the injuries accidental, suicidal, or homicidal? The first question — whether the injuries were inflicted during life ? — and the third question — were the injuries accidental, suicidal, or homicidal ? are fully discussed under the head of wounds. The fact of the body having been immersed in water will influence the decision of this question, only in so far as the injuries are altered in appearance by the continuance of the body in the water. Are the Injuries of such a nature as to account for Death before Submersion ? There are five different ways in which a body taken from the water may come to exhibit marks of violence. 1. A man may be murdered, and, when dead, thrown into the water; 2. He may receive severe injury from the hands of others or himself, and may then be thrown (or throw himself) into the water while still alive. 3. The body may MARKS OF VIOLENCE. 237 be bruised by the struggles which the drowning man makes to save himself. 4. It may be borne by the violence of the stream against some obstacle. 5. The body may sustain severe injury in the very act of falling into the water. 1. On the supposition that a man has been murdered and thrown into the water quite dead, we should expect to find an absence of all the signs of death by drowning ; with the exception only of such as may be present under certain circumstances already mentioned, such as uncommon depth of water, or advanced states of putrefaction. 2. On the supposition, again, that a man found in the water had first been severely injured and then thrown in whilst still alive, we might ex])ect to find some at least of the signs ali-eady mentioned, and these might be sufficiently marked to enable us to come to a decision ; but this would, of course, depend on the strength still left to the drowning man, after the violence inflicted upon him. 3. The injuries which the body might sustain through the struggles of the drownmg man would not be such as to raise any question of the true cause of death. They would consist of bruises more or less ex- tensive and severe, but not so severe or extensive as to endanger life. 4. The injuries which may be inflicted on the body by the violence of the stream would also consist of bruises more or less extensive. It is very unlikely that such severe injuries as dislocations or fractures could originate in this way. 5. Falling into the Water. — There is no doubt that considerable injury may be inflicted if a person falls or throws himself from a con- siderable height upon a hard bank or pier of a bridge. Fracture of the skuii or limbs, extensive bruises, and severe lacerated wounds may be readily accounted for by this cause. Dislocation of the extremities is also a possible consequence of the mechanical obstacle presented by the water to the body falling from a great height. This accident happened many years since, as stated by Dr. Gordon Smith, to a man who was in the habit of jumping from the parapet of London Bridge into the Thames for a wager. He had previously performed this feat with impunity, but the last time he sank and was drowned. Both arms were found dislocated, in consequence, it is thought, of his having fallen with them in the horizontal posi- tion, instead of holding them close to his sides. Two cases ai'e also recorded (South's edition of Chelius's Surgery, vol. i. p, 532), the one of fracture of the body and arch of the fourth cervical vertebra, the other of fracture of the body of the fifth cervical vertebra, made in jumping into the water, due to the violent muscular effort to avert collision with the bottom, by drawing back the head. The medical man should, therefore, first ascertain whether the drowned man fell from a height into the water, whether the stream is rapid, and what obstacles present themselves ; and if on careful exami- nation he finds that there are no such causes as these to account for the violence which the party has sustained, he may fairly trace that vio- 238 DEATH BY DROWNING. lence to some cause preceding the immersion. In bodies found in shal- low still water, marks of violence afford strong presumption of homicide. Having convinced ourselves, after a careful examination, that death took place by drowning, another question arises — Was the drowning the result of Accident, Suicide, or Homicide? — This question is exceedingly difficult to answer. For if there are no marks of violence on the body, it is not possible to say whether the man fell in, or jumped in, or was pushed in. Again, in respect of bodies found in running streams, it may not be possible to ascertain at what point the body entered the water ; hence we are deprived of such information as rpight have been obtained from a close examination of the spot where the body is found. Nor if we find the hands of the drowned man full of leaves or grass, showing that he struggled hard whilst in the water, can we affirm that he was thrown or pushed in by others ; for, if he fell in, he would do precisely the same. Nor again, does the fact of a man being drowned in a shallow stream of water render the idea of homicide improbable ; for if a sti-ong man were to hold the head of a weak or infirm one in a basin of water, he might drown him just as effectually as in a deep stream. On the other hand, it should be borne in mind that cases of suicidal drowning in shallow water, or in very narrow spaces, such as small house-cisterns, are by no means rare. It is evident, from what has been stated, that where there are no marks of violence on the body, we have no means of determining whe- ther the drowning was the result of accident, suicide, or homicide. Nor does the discovery of external injuries throw any light upon the question, unless those injuries are of such a kind as that they could not have been inflicted by the person himself previous to immeision, or by the accidental striking of the body against an obstacle in entering the water, during the death struggle. There is one case which would at first sight seem conclusive as to homicide, and that is where a body is found in the water, tied hand and foot. Dr. Smith, however, relates the following case : — In July, 1816, the body of a gauging-instrument maker, who had been missing for some days from his home, was discovered floating down the Thames. On being taken out, his wrists were found tied together and made fast to his knees, which were in like manner secured to each other. He had been in a state of mental derangement for two years. The cord with which he had tied himself was recognised as one that had hung from the ceiling over his bed, and by which he used to raise himself up, as he had been confined to bed for some weeks. He was a good swimmer, and it was presumed he had taken the precaution to prevent himself from employing that power. The verdict in this case was, " Found drowned." Two other cases of a similar kind are on record, one by Fodere', in which the hands and fingers were tied together with a silk riband, in numerous folds: and another in the ninth ] MEANS OF RESTORATION. 239 volume of the ' Anuales d'Hygifene,' in which the feet, wrists, and neck were tied. Fodere' in the one case, and the medical examiners (Marc, Guichard, &c.) in the other, gave their opinion in favour of suicide. In such cases as these it would be necessary to determine whether the knots or folds admitted of being made with the teeth, or by any move- ments of the hands or limbs. Treatment of the Drowned. — Before describing the proper treatment of the drowned, it may be well to recall the fact that in the majority of deaths by drowning the cause of death is apncea, simple or mixed ; and that the means to be adopted are those which would be prescribed in other cases of suffocation, with certain modifications obviously sug- gested by the circumstance of the death having occurred in the water. The contact of the v/ater, for instance, will account for a lower temperature of the surface than would exist as a simple consequence of death from apnoea. Hence the necessity for more prompt and sustained attempts to restore the heat of the surface. Such provision as may not be inconsistent with the use of other means of restoration should also be made for relieving the lungs and stomach of the water which had entered those organs. The following rules for the treatment of the drowned are in accord- ance with the improved method of the late Dr. Marshall Hall. Strip the body, and carry it, resting on the belly with the face downwards, at once to a house close at hand, or to a convenient spot in the open air; and wipe the body and face dry. Raise the body into the sitting posture, and endeavour to excite respiration by the use of smelling- salts, by tickling the nostrils and throat with a feather, and by dashing warm water on the face and chest. If these means of exciting respira- tion happen to be at hand, use them promptly, and desist if they do not produce an immediate effect: if not at hand, proceed at once to replace the body on the face with the arms crossed under the forehead. Then turn it to the side and back again to the face about fifteen times in a minute. In the short intervals apply friction and pressure to the ribs, and along the spine, and carry the hands with a firm pressure along the extremities from below upwards. If warmed blankets can be procured place them under and round the body, and rub the body with hot towels. Persevere with this treatment, with the assistance of other persons, for several hours, or until some of the more certain signs of death have made their appearance. (See p, 208 et seq.) DEATH BY HANGING. Death by hanging is of common occurrence. In the five years 1852-56, 494 persons perished in this way, in England and Wales, of whom 384 were males and 110 females. Of the 494 deaths by hang- ing no fewer than 451 were ascertained suicidal acts, of which 349 were by men and 102 by women. Judicial executions account for 7 of the deaths, so that only 487 were voluntary acts, of which 451 were 240 DEATH BY HANGING. suicidal. In the whole five years only one death of a child under five yeare old was set down as an act of homicide. It is probable that all the other cases were suicidal. As the cause of death is the same in hanging, strangulation, and Buftbcation, it may be well to make a fev/ preliminary observations on these modes of death, before proceeding to examine them sepaiately. Though, in common language, death from any of these three causes is due to suffocation, the term suffocation has in medico-legal language a meaning quite distinct from that of the other two. Whenever death is produced by any impediment to the respiration, which does not act by compressing the larynx or trachea, it is said to be due to suffocation. Thus a man is said to be suffocated if his mouth and nostrils arc closed, or if the action of the muscles of respiration is prevented by mechanical pressure either on the chest or abdomen. Certain noxious gases, too, are said to destroy life by producing suffocation. The subject of suffocation, then, separates itself at once from those of suspension and strangulation, inasmuch as it includes all those cases of violent death in which the respiration is suspended, by causes other than pressure on the throat. Our attention, therefore, must be directed, in the first place, to death by suspension and strangulation, in both of which pressure is exercised on the air-tube and throat. This piessure may be applied to any part of the throat, and not only so, but it may be applied to the .same part in different ways and degrees. The most simple mode is by direct pressure on the trachea with the fingers. Here the cause of death is obvious ; it is the same as in many cases of drowning ; the same as in suffocation — viz. apnaa (asphyxia). Death takes place in consequence of the mechanical hindrance to the respiration. But the cause of death is not so clear when the entire circumference of the neck is subject to compression ; for in this case not only is the larynx or trachea subject to pressure but the blood-vessels also suflfer. In some instances both the air-tubes and the vessels are implicated ; in others the air-tubes suffer the chief compression and the vessels escape ; in otheis, again, the air-tubes escape and the vessels suflfer all the pressure. The respiration and circulation are most completely impeded when a cord is fixed round the lower part of the neck, so as to embrace the trachea, and the huge vessels at their enti-ance into and exit fi-om the chest ; t)r when the cord is applied, or drawn by the weight of the body, beneath the lower jaw. Both functions are less interfered with when the cord is fixed directly over the larynx, as the projections of the os hyoides and thyroid cartilage in some degree defend the air-passage and blood-vessels from pressure. Now this variation in the position of the ligature, and in the pressure which it exercises on the organs of respiration and circulation respec- tively, explains the difference in the length of time required to destroy life in all those cases in which death does not take place instantaneously from injuiy to the spinal cord. But the circumstance of the air-tubes and blood-vessels being, in all other cases, compressed simultaneously CAUSE OF DEATH. 241 gives rise to the question, whether the compression of the air-tube or of the blood-vessels is the immediate cause of death. Is death, in other words, produced by apnoea, or by apoplexy ? It was formerly the general belief that death was produced by apoplexy : and this opinion was not unreasonable ; for it is well known that mere pressure with the fingers on the carotid arteries will cause sleep, by checking the supply of blood to the brain, and apoplexy is often brought on, in persons predisposed to that disease, by the pressure of a cravat impeding the return of blood through the veins. The possibility, therefore, of apoplexy being brought about by pressure on the large blood-vessels is not to be doubted ; but the question still recurs — in those cases of suspension or strangulation in which the air-tube and blood-vessels are simultaneously compressed to which of the two pressures is death to be attributed ? Both causes doubt- less combine to produce the fatal result, but there is every reason to regard the stoppage of the respiration as the essential cause ; for death by apnoea would be much more speedily and certainly induced by a complete or partial stoppage of the breathing, than fatal apoplexy by the complete or partial arrest of the circulation. But an appeal may be made to actual experiment for the decision of this question. A dog was suspended by the neck with a cord, an opening having been previously made in the trachea below the place where the cord was applied. After hanging for about three quarters of an hour, during which time the circulation and the breathing went on as usual, the animal was cut down, and did not appear to have suffered materially. The cord was then shifted from above to below the opening into the trachea, so as to stop the ingress of air into the lungs ; and the animal being again suspended, was in a few minutes completely dead.* In this experiment the compression of the vessels was probably less than it would be in many cases of death from hanging in the human subject, in which the violence employed, the height of the fall, and the weight of the body combine to tighten the cord, and thus exercise the strongest pressure on the vessels as well as on the air-tube. A similar operation on the human subject is described by Smith (' Forensic Medicine,' Appendix, p. 561.) " A man of the name of Gordon was executed at Tyburn, in April, 1733. Mr, Chovet having, by frequent experiments on dogs, dis- covered that opening the windpipe would prevent the fatal conse- quences of the halter, undertook to save Gordon, and accordingly made an incision in his windpipe, the effect of which was, that when Gordon stopped his mouth, nostrils, and ears, for some time, air enough came through the opening to allow of the continuance of life. When hanged, he was observed to be alive after all the rest were dead; and when he had hung three quarters of an hour, being carried to a house in the Tyburn road, he opened his mouth several times and * ' CyclopEcdia of Practical Medicine,' Asphyxia. R 242 DEATH BY HANGING. groaned ; and a vein being opened he bled freely. No further attempts succeeded in eliciting any other signs of life. The want of success probably was to be attributed to the great weight of tlie man, by which the compression of the vessels of the neck must have become more effectual than in ordinary cases, and perhaps' at the same time the opening into the trachea was not sufficiently free." It is obvious that the same results would happen if for the compression of the neck brought about in suspension by the weight of the body, an equal pres- sure were exercised directly by strangulation. It appears, then, that when the windpipe as well as the large blood- vessels suffer compression, death may be attributed to apnoja ; when the respiration is free, or but slightly affected, pressure on the vessels may cause death by apoplexy, but more slowly ; and that when respi- ration and circulation are both impeded, both may contribute to the fatal result, though the stoppage of the respiration is the more efficient. It has been suggested that the immediate cause of death in hanging and strangulation is pressure on the nerves which are subordinate to the function of respiration ; but as such pressure does not prove fatal till the lapse of many hours, this explanation may be rejected. Having now examined the questions which are common to death by hanging and by strangulation, the subject of death by hanging may be resumed. Death takes place very suddenly in certain cases of suspension. This may arise from two causes : from fear producing syncope as in some cases of drowning ; and from injury to the spinal cord by luxation of the cervical vertebrae, fracture of the odontoid process, or rupture of the intervertebral substance. These injuries to the spine are caused either by the fall of the body from a great height, or from a rotatory motion given to the body at the moment of the fall. Death after hanging takes place, then, in different ways and different intervals of time. When it occurs most promptly it may be referred to injury sustained by the spinal marrow above the origin of the nerves of respiration, and more rarely to syncope from fright. Next in point of rapidity will be the death from apnoea^ and the least rapid that by apoplexy. We are not without information as to the sensations that accompany death by hanging. Suicides who have been saved from death, and philosophers who have instituted experiments on themselves, have both contributed something to our knowledge. It appears that these sen- sations are not always the same ; and the difi'erence probably depends on the various degrees in which the windpipe and blood-vessels are compressed. Some have retained no recollection of what happened to them ; others were conscious of sudden loss of sense and motion ; in others a deep sleep was ushered in by flashes of light, by a bluish flame, by brilliant circles of colours, or by oculai- illusions of a more THE MARK OF THE CORD. 243 definite kind, accompanied by hissing or singing in the ears. In other instances, again, the sensations are stated to have been extremely plea- surable, though of short duration. These sensations resemble those that occur in cases of disordered cea'ebral circulation, and those that precede the fits in some cases of epilepsy. But it is only in cases of suicidal hanging that these pleasurable sensations manifest themselves. In homicidal cases, when much vio- lence is used, the countenance expresses suffering; the eyes are bril- liant and staring, and seem to be bursting from their sockets ; and the eyelids open and injected; the tongue, swollen and livid, is forced against the teeth, or more or less protruded from the mouth, and compressed or torn by the contracted jaws ; the lips are swollen and the mouth distorted; and blood, or a bloody, froth, hangs about the mouth and nostrils ; the upper extremities are stiff, the hands livid, and the fingers so forcibly closed on the palm as to force the nails into the flesh ; and the convulsions are so violent as even to cause the expulsion of the contents of the bowels, and to produce erection of the penis, with expulsion of the urine, semen, or prostatic fluid. The cir- cumscribed rosy or violet discolourations on the trunk and extremities common to all cases of death by apnoea are strongly developed ; the course of the cord is distinctly indicated by some of the appearances presently to be described, but generally assumes the form of a well- marked bruise; and, on cutting through the skin, the muscles and ligaments of the windpipe are found stretched, bruised, or torn. The internal appearances are the same as in other forms of apnoea. The lungs are said to be sometimes distended with air, sometimes collapsed. The great difference in the two forms of hanging (suicidal and homi- cidal) is important ; for it explains the very different appearances dis- covered after death in the two cases respectively. Two principal medico-legal questions arise in regard to persons found hanged. 1 . Did the suspension take place during life, or after death ? and, 2, Was the hanging accidental, suicidal, or homicidal? 1 . Did the suspension take place during life, or after death ? The points most worthy of attention as bearing on the solution of this question are : — The mark of the cord ; The appearance of the countenance ; The position and state of the tongue ; The condition of the genital organs ; and the expulsion of the faeces. The Mark of the Cord. — It is now well ascertained that the ap- pearances on the neck due to suspension during life are by no means uniform. In homicidal cases attended by violence, and involving strong struggles, the neck sustains great injury, marked by the bruised appearance of the skin, and the torn state of the subjacent parts ; but in judicial and suicidal hanging much less injury is done both to the surface and to the deeper-seated parts„ In those cases (both judicial and suicidal), in which the position of 244 DEATH BY HANGING. the cord is mainly detentiined by the weight of the body, it follows jiretty closely the line of the jaw-bone, and there is an oblique indented mark, of the colour of a recent bruise, on the fore part of the neck, and yellowish brown, as if from a superficial burn, towards the angle of the jaw. Sometimes the bruise corresponds with the whole breadth of the ligature ; at others there is a deep gi-oove, bordered by two dis- coloured lines. The mark varies with the size of the cord and the materials of which it consists, being less distinct when a soft material, such as a handkerchief, is used, than when a hard ligature, such as a rope, is employed. When the material is hard and resisting, the ap- pearances on the neck indicate the number of times that the ligature has been passed round it, and even the material of which it consists. But in many cases of judicial and suicidal hanging, the mark of the rope consists at first of a simple depression without any change of colour, oblique if due to the weight of the body, horizontal if firmly fixed round the neck. After the lapse of several hours, the rope-mark assumes a light-brownish tint. If an incision be made into the skin the cellular membiane is found strongly compressed, so as to form a shining white band. Thfe appearances of a bruise are never developed at all. The countenance, as will be presently more fully stated, is at first pale and its expression natural, and it is not till several hours have elapsed that it assumes a livid tint, and still longer before it wears a bloated appearance. In a case of judicial hanging, in which the cord was removed soon after the body had been cut down, I observed merely a depressed circle on the fore part of the neck, and a slight excoriation, with a burnt appearance over the angle of the jaw. In a case of suicidal hanging with a small rope tied firnily round the neck, which was re- moved without delay, there was a white depressed line deeper at the back of the neck than in front and assuming a dusky hue after the lapse of several hours. The strands of the rope were distinctly marked, but there was no ecchymosis on any part of the neck. The appearances, then, produced by the cord in cases of hanging during life are not the same in all instances : in some cases there is the usual appearance of a bruise or ecchymosis ; in others there is merely an indentation of the skin, without discolouration, and a con- densed state of the subcutaneous tissues, resembling old parchment ; and these appearances may be combined at the angle of the jaw, or in other parts of the neck, with slight excoriations, or appearances like those produced by superficial burns. As the condensed, abraded, and burnt appearance of the skin may obviously be produced after death as well as during life, there remains only to consider as possible proof of death by hanging the value of the biniise or ecchymosis present in a certain proportion of the cases. The question, whether the appearances occasioned by the cord in an individual suspended during life, can be produced after death ? has been answered in the affirmative. In the chapter on Wounds and STATE OF COUNTENANCE, TONGUE, GENITAL ORGANS. 245 Mechanical Injuries, it will be shown, when speaking of the distinction between bruises inflicted during life and after death, that ecchymosis may be produced for some time after life is extinct. The rule which apphes to bruises in general will of course hold good with respect to this jmrticular form of bruise ; and accordingly Orfila proved, by experiments on the dead body, that, up to eighteen hours after death, precisely the same appearances may be produced as in suspension during life ; Devergie has produced the parchment-like condition of the skin and subjacent cellular tissue, as well as the ecchymosed appearance bounding the depression ; and Dr. Casper, of Berlin, succeeded up to two hours after death in producing ecchymosis resembling that occurring in hanging during life. It follows, then, that neither ecchymosis, nor the peculiar parchment-like condensation of the skin is a sure sign of suspension during life ; and that consequently the appearance of the neck, taken alone, is not conclusive as to the question under con- sideration. But a very considerable effusion of blood, a rupture of the trachea, a separation of its cartilages, a dislocation of the spine, a division of the coats of the vessels, or, indeed, any evidence of great violence would furnish a strong probability of suspension during life, or of suspension after strangulation, for it is highly improbable that much force would be used in suspending a body which had been pre- viously deprived of life by other means. State of the Countenance. — In death by hanging, whether judicial or suicidal, the countenance is usually pale, and the expression of the features natural. But this pallor of the face is followed, after a few hours, by a livid hue of the lips, eyelids, and face generally ; and, after a still longer interval, by a marked congestion of the countenance. There is nothing in the expression or colour of the face to show that suspension took place during life or after death ; but if the vessels of the head and face were found highly congested in a body recently cut down, it would furnish a probability in favour of suspension during life; for, suspension after death, though it might produce discolouration of the neck itself, could not cause turgescence of the vessels of the head and face. Position and State of the Tongue. — The same injected state of the base of the tongue, with swelling and protrusion of the organ, which occurs in other forms of death by apnoea, occurs also in death by hanging, and affords a strong probability of suspension during life. State of the Genital Organs.- — The genital organs of both sexes are affected in death by hanging. In the female, redness of the labia and discharge of blood have been occasionally noted, and in the male a more or less complete state of erection of the penis, with discharge of urine, of mucus, or of the prostatic fluid, is a frequent occuirence. It may be expected to be present in at least one case in three. But it must be borne in mind, that these appearances in the genital organs, when they do occur, are not characteristic of death by hanging or strangulation, for they have been observed in other forms of violent 246 DEATH BY HANGING. and sudden death, as in fatal gun-shot wounds of the brain, and of the large vessels, and in poisoning by prussic acid. It is probable that the fluid ejected from the urethra is not semen but mucus; for, in the report of the case of a criminal executed in America, (' American Journal of the Medical Sciences,' May 1840,) there was no priapism, but a fluid was discharged which is stated not to have con'' tained any seminal animalcules. This sign then, when present, is one of considerable importance, for it is strictly vital, and affords a sure proof of violent and sudden death ; and if combined with other exteraal signs of death by hanging, and characteristic internal appearances, would be nearly conclusive. On the other hand, the absence of erection and emission is no evidence that death was not due to this cause. Expulsion of the fwces. — The contents of the bowels are expelled in about one fourth of the cases of death by hanging ; but as this also happens in other forms of sudden or violent death, it is to be regarded as evidence of such mode of death, but not of death by hanging only. 2. Was the Hanging accidental, suicidal, or homicidal "? — Accidental hanging is of rare occurrence. One case is given by Dr. Smith : it was that of a girl who was swinging in a brewhouse, and near the rope used by her for that purpose was another for drawing up slaughtered sheep. In the course of the exercise her head got through a noose of this second rope, by which she was pulled out of the swing, and kept suspended at a considerable height, until she died. Dr. Taylor also relates a case communicated to him by one of his pupils. A boy ten years old had been amusing himself by fastening a piece of plaid gown to a loop in a cord, which was suspended from a beam in the room. In the act of swinging he raised himself, and gave himself a turn, when the loop of rope suddenly caught him under the chin, and suspended him until life was extinct. A playmate was witness of the occurrence. With the exception of a small number of cases of this class, in which the mode of death is obvious, the question under consideration is narrowed to this : Was the Hanging suicidal or homicidal ? The figures given from the returns of the Kegistrar General show that the probability is always strongly in favour of suicide ; and, for obvious reasons, hanging is a mode of death which a murderer is little likely to resort to. It presupposes a great disproportion of strength between the murderer and his victim, or a combination of two or three persons against one. In the figures just referred to, the solitary ascertained case of homicide in the five years 1852 to 1856, was committed on the person of an infant. There would be nothing in the appearance of the body itself, beyond the marks of a severe struggle, to distinguish the homicidal from the suicidal act ; but if a man were found suspended at a height from the ground which he could not by any possibility have reached,' and with DEATH BY STRANGULATION. 247 no object near on which he could have mounted, we might reasonably conclude that he was suspended by another. It was once supposed that a man found with the feet or some part of the body touching the ground was more likely to have been hanged by another than by himself; but careful observation has shown this to be an error, for suicides have been found in every imaginary position, and very many in such a posture that death must have been produced by strangulation, the suicide leaning forward so as to compress the windpipe. A great many cases, in which the bodies of suicides were found placed in every possible attitude, are given, illustrated by engravings, in an interesting paper in the fifth volume of the * Annales d'Hygiene.' As in most of the cases in which the body touches the ground the cord would not be so put on the stretch as to give it its usual oblique position, there would be no difference between such cases and cases of strangulation, except, perhaps, that in the latter the mark would be more distinct, and would embrace a greater portion of the neck. The marks of violent struggles on the clothes or person of the deceased, or of severe injuries, would justify a suspicion of homicide; but as severe and extensive injuries have been known to be produced by a suicide, and slighter injuries may take place accidentally, this criterion must be used with great caution. It appears, then, that in death by hanging, the presumption is always strongly in favour of suicide, but that we can rarely have the means of converting this presumption into certainty, or even of adding materially to its force. It may be well to add that cases are on record in which persons found suspended have been previously killed by strangulation or by other violence, as well as cases in which the true cause of death was poison. ^ DEATH BY STRANGULATION. This mode of death is rare compared with death by hanging. It accounts for fifty deaths in the year, of which thirty-seven in males and thirteen in females. Only half of these deaths were ascertained to be suicidal ; of which twenty in males and five in females. Homicide by strangulation, though much more common than by suspension, is of rare occurrence in grown-up persons, but common in infants. Death by strangulation differs from death by hanging only in the fact that the body is not suspended ; but some of the cases of suicidal hanging in which the body touches the ground might with equal propriety be set down to strangulation. Strangulation may be effected either by the uniform pressure of a ligature round the neck, or by direct pressure on the windpipe. In rare instances the two are combined, some object being introduced into the folds of the ligature, and placed immediately over the windpipe. 248 DEATH BY HANGING. From this distinction between death by hanging and death by strangulation, it follows that, as a general rule, the mark on the neck will differ in the two cases ; being oblique and high in the neck in death by hanging, circular and low down in death by strangulation. From this general rule, however, those cases of hanging must be ex- cepted in which tiie cord is firmly fixed round the ueck, and those in which the body is not completely suspended, but touches the ground ; and those rare cases of strangulation in which the ligature happens to be fixed somewhat obliquely. The mark in hanging, therefore, may happen to be circular, a;id that in strangulation more or less oblique. The introduction of a foreign body into the folds of the ligature would be indicated by the greater size and distinctness of the bruise over the windpipe. Another difference between strangulation and hanging is, that in strangulation much more force is used ; hence the mark on the neck will be more visible, and the injury to the subjacent parts more con- siderable; and this will be especially the case in homicidal strangu- lation, for the murderer generally uses more violence than is necessary to effect his purpose. The same questions arise in respect of strangulation, as of hanging — viz., 1. Was death caused by strangulation ? 2. Was the stran- gulation accidental, suicidal, or homicidal ? 1. Was Death caused by Strangulation'? — A cord applied a few hours after death would not produce that degree of ecchymosis which would result from the application of the cord during life ; and the turgesceuce of the countenance, as well as the characteristic post- mortem appearances, would be wanting. It is only, therefore, in suicidal cases, and in the scarcely conceivable case of slight forc6 being used by the murderer, or death taking place suddenly, from shock or syncope, that the appearances produced by a cord applied during life could resemble those due to its application after death. The same observations apply to direct pressure on the windpipe. As, moreover, hanging is known to be the more common suicidal gfct, the murderer is not likely to hide the real mode of death by simulated strangulation. It is much more probable that having strangled his victim, he should endeavour to conceal the real mode of death, by suspending the body or placing it in a position suggestive of suicide. In the well-known case of Bartholomew Pourpre, the deceased was first strangled and then suspended, and the mark of the cord was found at the lower part of the neck, while the teeth knocked in, and the bloody mouth, showed the foice which had been employed. The murderers of Sir Edmondbury Godfrey, after strangling him near Somerset House with a twisted handkerchief applied with great force, concealed the body for a time, and then carried it to Islington, where they threw it into a ditch, passed his own sword through him, and laid his gloves and other articles of dress on the bank, so as to excite the belief that he had committed suicide. WAS THE STRANGULATION SUICIDAL OR HOMICIDAL ? 249 The absence of blood from the wound, though tlie sword had passed through the heart, excited suspicion, which was fully confirmed by the discovery of a bruise, an inch broad, extending round the neck ; and a fracture of the cervical vertebrae, which rendered the neck so flexible that it could be turned from one shoulder to the other. The face which during life was remarkably pale, was livid and suffused, and the eyes bloodshot. 2. Was the Strangulation accidental, suicidal, or homicidal'? — That strangulation, like hanging, may take place accidentally, is proved by the following cases. An ingenious young man having nearly lost the use of his arms was in the habit of moving a heavy weight by means of a cord attached to it and passed round his neck. One morning, shortly after having retired to his own room, his sister discovered him sitting in a chair apparently lifeless. He was found to be quite dead, with the cord twisted round his neck. On cutting the cord, the weight fell on the floor. There was little doubt that the deceased had attempted to move the weight in the usual way, but that it had slipped behind, and had compressed the trachea so as to produce strangulation. (Dr. Smith.) In July, 1839, Elizabeth Kenchan, an extremely dissipated, drunken, and disorderly woman, went to bed intoxicated, with her bonnet on, and in the morning was found strangled in her bonnet strings. ' It appears that she fell out of bed, that her bonnet became fastened between the bedstead and the wall, and that she, being too drunk to loosen the strings, was consequently strangled. These rare cases of accident would be easily known to be such by the position of the body and the circumstances of the case. In a few cases, then, death by strangulation has been due to acci- dent; but if we have convinced ourselves that death did not take place in this way, the question is narrowed, and assumes this shape : — Was the Strangulation suicidal or homicidal i — Strangulation appears to be a suicidal act in about half the recorded cases. As it is difficult for a man to strangle himself by the pressure of his hands even with the aid of a ligature, some mechanical contrivance is usually resorted to. A case is related by Orfila, of a suicide who was found lying dead in his bed, with two cravats twisted several times round his neck. Dunlop relates the case of a Malay who used a small stick for the same purpose. In the year 1838 a Mr. Watson, aged 88, strangled himself by placing a poker through the tie of his hand- kerchief and twisting it round and round. In another instance, the handle of a pot was employed, and several similar examples have been put on record. Strangulation by pressure of the hand on the trachea may be safely assumed to be homicidal, as in the following case. A trial for murder by strangulation took place at the Chester assizes, in April, 1835. The prisoner, who was a robust man, upon some slight provocation, 250 DEATH BY HANGING. seized the deceased by the cravat, and pressed him firmly by the neck against a wall, until he was dead. On examining the body, the face was found to be livid and swollen, and the features distorted. There was also a considerable discolouration and depression on that part of the neck to which the pressure had been applied. The prisoner was seen to commit the crime, and the case was clearly proved against him, but he was acquitted on the ground of insanity. It has been alleged that fatal pressure with the fingers on the windpipe might occur accidentally ; but this may be safely pronounced to be impossible. An unsuccessful attempt to attribute death to this cause was made in the well-known case of Beddingfield. In 1763, a man named Beddingfield was found dead in his bed- room, and the charge was laid against his wife and man-servant. The medical testimony was very unsatisfactory, as no dissection had taken place, but it was pi-oved that there were marks about the neck resem- bling those of fingers. A contradictory account was, however, given of the number : one surgeon said a thumb and three fingers ; the other, a thumb and four fingers ; while another witness, who also saw the marks, at the inquest spoke of two only, " which looked as if the blood was set in the skin." The defence was, that the deceased had fallen out of bed, and was found lying on the floor on his face, with one hand round his neck. The discrepancies in the testimony, and the omission of dissection, might, however, have led to subsequent doubts, had not one of the condemned persons confessed that he had strangled Beddingfield in his sleep, by seizing his throat with his left hand ; and that though the deceased struggled violently and made some noise, yet he soon accomplished his purpose. The following is a case of homicidal strangulation by a foreign body introduced into the ligature. Dr. Clench, a London physician, was called out of bed by two persons on the night of the 4th of January, 1692, to visit a sick friend. He entered a hackney coach with them, and drove about several streets in the city for an hour and a quarter. The two persons then left the coach, and sent the driver on an errand. When the coachman returned, he found Dr. Clench sitting on the bottom of the coach, against the front seat, with his head on the cushion. Thinking him in liquor, he shook him, but obtained no answer. He then called the watch, and they found him strangled by a coal wrapped in a hand- kerchief, and applied directly over the windpipe. The coachman had heard no noise while driving the carnage. The appearances present in the body in cases of forcible strangulation may be inferred from the evidence of Mr. W. Wilson in the case of Hector M' Donald, tried and convicted of the culpable homicide of his wife, at Inverary, April 1857. There was an abrasion on each side of the windpipe, five abrasions on the left arm, three on the right arm: the skin on the front and sides of the neck, and on the upper part of the chest was blackened. On the throat there were the marks of a DEATH BY SUFFOCATION. 251 thumb and three fingers. The bruises were such as to justify the belief that the throat had been grasped by the left hand, of which the wrist was pressed upon the chest, and that the right hand had grasped the left arm of the victim. The internal appearances were highly characteristic of death by apnoea. The substance and membranes ot the brain were injected ; the right side of the heart contained a quantity of dark fluid blood : the left side was nearly empty. The lungs also contained a quantity of dark fluid blood. All the internal viscera were healthy. DEATH BY SUFFOCATION. Under this head are comprised all cases of apnoea, not produced by direct pressure on the windpipe, with the exception of drowning, which has already been treated separately. On an average of the five years 1852 to 1856, 708 deaths by suffo- cation occurred, of which 427 in males, and 281 in females. Of the whole number, 106 were infants killed by overlying, and about 180, also infants, were suffocated by bed-clothes. Fifty-seven, of whom the majority were young children, were suffocated by their food, 38 by gases, chiefly carbonic acid. Two suicides, five murders, and one manslaughter by suffocation are reported to have happened annually. Suffocation may take place in many ways. The mouth and nostrils may he stopped by accident or by force, A person in a state of helplessness, from whatever cause, may fall on the face and be suffocated by water or loose earth ; and new-born children by the discharges, by the bed-clothes, or by being overlaid in bed. Murderers have also sometimes despatched their victims by this means. Mechanical Pressure on the Chest. — This may occur from accident, as when a quantity of earth or rubbish falls upon a man ; or as a homicidal act, combined with strangulation ; the murderer pressing with his whole weight upon the body, and compressing the larynx or trachea with the hand. Sometimes suffocation is effected, as by Burke and Bishop, by compressing the chest and closing the mouth and nostrils at the same time. Suffocation by pressure on the chest was also resorted to in bar- barous times as a torture, and constituted part of the peine forte et dure of our ancient law. A risk of accidental suffocation from pressure on the chest has sometimes been incurred in taking casts with plaster of Paris. Persons have also been pressed to death in a crowd. On the 14th of June, 1837, no less than twenty-three persons lost their lives at the Champs de Mars in this way, death being due partly to suffocation and partly to severe injury to the chest. Closure of the glottis. — This also may occur accidentally, as in the 252 DEATH BY SUFFOCATION. 57 cases mentioned above as having been suffocated by food. When this happens in adults they are usually in a state of intoxication, or in a fit. Thus Paris and Fonblanque quote the case of a patient who was seized, after a heavy meal of pork, with an epileptic fit, during which he died ; when, upon opening the trachea, it was found to contain a quantity of animal matter, resembling the pork on which he had recently dined. Among familiar examples of accidental suffocation may be cited the death of Anacreon, attributed to a grape-seed ; and of Gilbert the poet from swallowing a piece of mutton. There is a case on recoid of suffocation caused by swallowing a bee in some honey ; another in which death was caused by slaked lime getting into the larynx, and producing violent inflammation there. Tumours in the glottis have led to the same result. Examples of suicidal suffocation are afforded by slaves who, both in ancient and modern times, are alleged to have swallowed their tongues. In other instances, some article of dress, such as a hand- kerchief has been swallowed, and one case of determined suicide was brought about by swallowing a cork bristling with sharp pins. The preparation is in the museum of King's College. ^ Suicidal suffocation by the vapours of charcoal «re not common in England but very frequent in France. Suffocation is not a mode of death frequently resorted to by mur- derers. When the victims are young and vigorous adults, the force required is such as to reveal the cause of death by external marks and internal appearances; but where the body is very weak from any cause, as in the new-born infant, the old man, or the intoxicated, suf- focation is not very difficult to effect, and, if unaccompanied by violence, might not betray itself by the state of the body externally or internally. The post-mortem appearances present in well-marked cases of death by suffocation may be deduced from the account given by Dr. Ollivier of Angers, of the persons suffocated in the Champs de Mars. In all the twenty-three persons, without exception, the skin of the face and neck was of a uniform violet tint, spotted with blackish ecchymoses. In nine there was infiltration of blood under the conjunctiva of the eye; in four, sero-sanguineous froth running from the mouth and nostrils ; in four, blood running from the nostrils ; in three, blood flowing from the ears ; in seven, fractures of the ribs ; in two, females, fracture of the sternum. In sixteen bodies that were opened, the blood was black, diffluent, and filling all the large veins at the right side of the heart. The pulmonary tissue was mostly of a reddish brown, and in three quarters of each lung, posteriorly, there was a considerable accumulation of black and liquid blood ; but there was no ecchymosis, either on the surface or in the substance of the lungs, except in one case. In all the cases in which there was infiltration of blood benea'th the conjunctiva, and in those in which blood flowed from THE VICTIMS OF BURKE AND BISHOP. 253 the ears, the vessels of the pia mater and substance of the brain were gorged with blood. In consequence of the comparatively slight injuries caused by suffo- cation, this mode of death was, previous to the passing of the Anatomy Act, selected by the murderers Burke and Bishop. Burke, with his female accomplice, Macdougall, was tried at Edinburgh in 1828, and Bishop, with Williams and May, in London, in 1831. Burke destroyed the deceased, Margery Campbell, by sitting on her body, covering her mouth and nostrils with one hand, and applying the other forcibly under the chin. Fifty-nine hours after death, the eyes were closed ; the features were found composed, as in deep sleep, red, and somewhat swollen ; the lips of a dark colour; and the conjunctivae of the eyes much injected with blood. There was a little fluid blood on the left cheek, apparently from the nostrils; the tongue was not protruded or torn by the teeth, but there was a slight laceration on the inside of the upper lip opposite the left eye-tooth ; the cuticle under the chin was much ruffled, and the surface of the true skin, when laid bare, was dry and biown ; but there was no ecchymosis. The integuments, except on the face, were per- fectly free from lividity. The joints were flaccid. There was no effusion of blood or laceration of the paits around the windpipe, and no injury of the cartilages, but the os hyoides and thyroid cartilage were further apart than usual, in consequence of the stretching of the interposed ligament. The following wei'e the internal appearances : The membrane of the windpipe healthy, with here and there some tough mucus, not frothy, and a few points of blood between it and the membrane. The organs within the chest were'perfectly natural ; the lungs remarkably so, and unusually free of infiltration. The blood throughout the body was black and fluid, and accumulated in the large veins, and in the right cavities of the heart. The abdominal viscera, with the exception of incipient disease of the liver, were healthy. The brain also was quite healthy, and presented a little more turgescence of vessels than usual ; and there were three extravasations of blood iij the scalp, but without corresponding external bruise. There were some marks of violence on the limbs, considerable effusions of blood among the muscles of the neck, back, and loins, and on the sheath of the spinal cord. The posterior ligamentous connections between the third and fourth cervical vertebrae were torn. These injuries to the back were shown to have been occasioned after death by the forcible doubling up of the body. It should be added that a ' handful ' of clotted blood was found near the body. In the case of Carlo Ferrari, the victim of Bisliop and Williams, the appearances from which suffocation might have been inferred were even less strongly marked. The face, it is true, was swollen and con- gested ; the eyes blood-shot, and the hps tumid ; but the lungs were quite healthy and not congested, the heart was contracted, and all its cavities quite empty. But these exceptional appearances were explained, 254 DEATH BY SUFFOCATION. by the fact, that the murderers, after stupefying their victim with liquor, lowered his body into a well with the head downwards, taking care to keep his mouth below the level of the water. In this case, too, there was some extravasated blood under the scalp, among the muscles of the neck, and on the spinal cord. The fresh state of the body, the appearance of the countenance, and a wound upon the left temple com- bined to excite suspicion, and led to the committal and conviction of the murderers. In both these cases death was certainly caused by suffocation, and yet the appearance of the bodies was not such as to lead at once to the conclusion that death had happened in this way. The medical exa- miners, in both cases, were inclined to ascribe the deaths to the injury done to the spine, which was afterwards proved to have been occasioned after death by the forcible doubling up of the bodies in packing them. In allusion to the opinion expressed by some medical men, that the signs of suffocation are so strongly marked as of themselves to arrest at- tention. Dr. Christison observes : — ** In the body of the woman Camp- bell, no person of skill, whose attention was pointedly excited by being told that from general circumstances murder was probable, but the mahner of death unknown, could have failed to remark signs that would raise a suspicion of suffocation. But if his attention had not been roused ; if, for example, he had examined it in the anatomical theatre of an hospital, without knowing that suspicions from general circumstances were entertained regarding it, he might have inspected it even mmutely, and yet neglected the appearances in question. Nay, a person of skill and experience would have been more likely to do so than another, because every one who is conversant with pathological anatomy must be familiar with such or similar appearances, as arising from various natural diseases." Dr. Christison then draws attention to the close resemblance between the appearances present in the body of Campbell and those observed in the body of a man who died of dysentery, adding that the ' vascularity of the conjunctivae, and the contusions on the legs made the only difference.' * * ' Cases and Observations in Medical Jurisprudence, Ed. Med, and Surg. Journal,' vol. xxxi, p. 243. (1829.) 255 CHAPTER III. WOUNDS AND MECHANICAL INJURIES. In this Chapter it is proposed to treat of all injuries inflicted on the body by mechanical means, excepting the several forms of death by suffocation treated of in previous chapters, and injuries by fire, and by lightning, which are reserved for separate examination in succeeding ones. All injuries, therefore, which one man inflicts upon another, whether by cutting or bruising instruments, by his own person, or by forcing him against an obstacle, will have to be considered under this head. Tor the punishment of all such injuries when maliciously inflicted, the statute law makes provision, no less than for stabbing, cutting, shoot- ing, drowning, strangling, and suffocating, by the insertion of the words " or shall by any means whatever cause to any person any bodily injury dangerous to life." In examining so large a subject as this of wounds, or mechanical injuries, methodical an-angement is especially necessary. The different kinds of mechanical injury will have to be separately considered, the questions common to all^ such injuries must be discussed, and the peculiar way in which th'ey affect the more important organs of the economy must receive due attention. Three kinds of mechanical injury will have to be separately exa- mined : — wounds in the common acceptation of the term, gunshot wounds, and mechanical injuries not usually designated as " wounds." The old surgical definition of a wound * makes it to consist in a solution of continuity. Mechanical injuries, therefore, may be con- veniently divided into such as are without solution of continuity and such as are with solution of continuity. The first will include, con- tusions, concussions, simple fractures, dislocations, and sprains. The second comprises incisions, punctures, and lacerations, compound frac- tures, and gun-shot wounds. The two classes of injuries, whatever the parts which they affect. * ' A wound is a solution of continuity in any part of the body suddenly made, by anything that cuts or tears, with a division of the skin.' ' By the word skin, I understand not only the external cutis, but also the inward mem- branes of the gullet, ventricle, guts, bladder, urethra, and womb, all of which are capable of wounds from sharp instruments, either swallowed or thrust into them.' — Richard Wiseman's ' Chirurgical Treatises,' book v., chap, i. 256 WOUNDS. have some points common to all the forms of violence included in the class. Thus, almost all injuries affecting the deeper-seated parts of the bodv are accompanied by external traces of the violence which pro- duced them, whether that violence caused a solution of continuity or not. Hence, in the greater number of cases we shall have traces of the injury on the surface, and on this account it will be neces- sary to examine minutely the subject of bruises and incisions involving the external parts of the body. The arrangement which it will be convenient to adopt has now been sufficiently indicated. The whole subject will be best examined under the following heads: — 1. The eharacters of contused wounds, and of injuries unaccompanied by solution of continuity. 2. The characters of incised wounds, and of those accompanied by a solution of con- tinuity. . 3. The characters of gun-shot wounds. 4. The detection of spots of blood on weapons and clothes. 5. The questions common to all forms of mechanical injury. 6. Wounds as they affect the several important organs of the economy. 1. THE CHARACTERS OF CONTUSED WOUNDS, AND OF INJURIES UNACCOMPANIED BY SOLUTION OF CONTINUITY. A blow with a blunt instrument gives rise to an appearance on the surface familiarly known as a bruise, and, in scientific language, as an ecchymosis. A bruise consists in a discolouration of the skin ])roduced by extra- vasation of blood into the cellular membrane. The blood may be thrown out in the superficial or in the deep-seated parts. When thrown out in the superficial parts, and especially in the lax and yielding portions of the skin, the colour makes its appearance at once. When the effusion is deeper seated, days may elapse before any dis- colouration of the skin takes place, and then it is not blue, as in super- ficial parts, but of a violet, greenish, or yellowish hue ; nor is it always immediately over the eff'usion of blood. The colour is not developed to its full extent at once ; but it con- tinues to'deepen for five or six hours. When blood ceases to flow from the broken vessels, serum is eff"used, and inflammation is set up, and in this manner the extent of the bruise is iucreased. The colour of the bruise also undergoes a change, and passes from deep blue through shades of green, yellow, and lemon colour. After a further inten^al, the effused fluids are absorbed, and the colours first fade and then wholly disappear. If the parts have received great injury, the inflammation runs on to suppuration, and an abscess forms if the injury is deep, an ulcer if superficial. The change of colour begins at the circumference of the bruise, where the eff'used fluids are small in quantity, and travels in- wards towards the centre, where the blood is in larger quantity, and where the deep blue colour often remains after the rest of the bruise CHARACTEKS OF CONTUSED WOUNDS. 257 has completely changed its appearance. In bruises of any extent, and in those parts which contain much blood, coagula are formed. The extent of the bruise, and the rapidity of the changes which it undergoes, will depend on a variety of circumstances, such as the force used, the size and character of the weapon, the age and constitution of the sufferei-, the full or empty state of the vessels, and the tension or laxity of the skin. As the form of a bruise is mainly determined by the shape of the weapon with which it is inflicted, it often furnishes of itself strong presumptive evidence against an accused party. Thus Starkie, in his * Law of Evidence,' instances an attempt at murder in which the prosecutor, in his own defence, struck the assassin violently in the face with the key of the house-door. The bruise which followed corresponded precisely in shape to the wards of the key, and it was chiefly through this very singukr and unexpected piece of evidence that the assassin was afterwards identified and brought to trial. The subjects of death by hanging, strangulation, and suffocation, furnish familiar examples of the correspondence of bruises with the cause that has produced them. Though the seat of the discolourations which constitute a bi'uise, is, as has been stated, the cellular membrane, it is not confined to this, but involves more or less the substance of the true skin. Bruises are thus distinguished from cadaveric lividity. (Seep. 213.) The amount of injury, and consequent extent of bruise inflicted by a blow, will also depend, as has just been stated, upon the condition of the parts involved in the injury. A boxer in training Avould scarcely be marked by a blow. which would disfigure a person in an ordinary state of health, and in severe cases of scurvy the slightest touch will occasion a bruise closely resembling that produced in healthy persons by greater degrees of violence. Blows, even when very severe, do not always produce marks of injury on the surface. Thus blows on the abdomen, severe enough to rupture the viscera, do not always bruise the skin, though they some- times lead to the effusion of blood between the muscles. In order that the appearance of a bruise may be produced, it is necessary that there should be comparatively hard and unyielding parts beneath the skin ; and, on the other hand, where we find severe injuries of the hard parts, such as fractures of bones, without any trace of bruises on the skin, we should be cautious how we attribute such injuries to the blows. Can the Appearance of a Bruise he 'produced after Death ? This question is answered by the experiments of Dr. Christison. from which it appears, that, up to two hours after death, and, in rare cases, after three hours and a quarter, appearances may be produced more or less closely resembling bruises inflicted during life ; blood is effused into the cellular membrane, on the surface of the cutis, and even into its substance ; and the blood thus effused is found to coagulate. 258 WOUNDS. Means of dtstmjuishing Bniises inflicted during Life from those inflicted after Death. — In certain cases this distinction is easy. If there is much swelling, if there is any change of colour, or any sign of inflammation, the bruise must have been inflicted during life. If on cutting into the bruise, the effusion of blood is found to be considerable, and the clots large, the presumption is strongly in favour of the bruise having been inflicted during life. So also if the cutis is discoloured from the effusion of blood into its texture. This is a valuable diagnostic mark, except in the case of bruises inflicted within a few minutes after death, when, judging from the analogy of incised wounds, we may expect the same appearances as in those produced during life. The same cff'usion of blood, which, on the surface of the body, gives rise to the appearance of a bruise, may occur in the internal parts as the result of violence, and yet leave very slight traces on the surface, or none at all ; and it is therefore important to ascertain whether such effusions of blood in deep-seated parts may take place after death as well as during life. This question may be safely answered in the affirmative. In the body of Margery Campbell, the victim of Burke, in addition to the signs of suffocation, described in the last chapter, there were marks of severe injury to the back, to which Dr. Christison was at first inclined to attribute her death. On examining the back, blood in a semi-fluid state was found under the trapezius muscle, near the inferior angle of the scapula, as also in the left lumbar region, but there was no corresponding bruise on the integuments. Blood was also found in the cervical and dorsal regions, especially in the former. The ligaments connecting the vertebraj posteriorly were ruptured, but there was no fracture. On the sheath of the spinal cord opposite to the rupture, there was a mass of semi-fluid black blood, about the thickness of a penny- piece, and one inch in diameter ; from this a thin layer of the same kind of blood extended along the posterior surface of the sheath, as far down as the lowest dorsal vertebrae. The spinal cord was uninjured, and there was no blood under its sheath. Dr. Chris- tison, by experiments on the dead body, was able to prove, that all these marks of violence might be produced as much as seventeen hours after death ; for he succeeded in producing them by bending the head forcibly down upon the chest in a subject which was cold, and in which all the joints were stiff. In the body of Carlo Ferrari, a similar effusion of blood was discovered. Coagulated blood to the amount of five or six ounces was found extravasated among the deep-seated muscles of the neck, from the occiput to the last cervical vertebra. A large quantity of fluid blood was also found both in the upper and lower part of the spinal canal, exterior to the sheath of the cord. There was no appearance of injury either to the vertebrae or their ligaments; there was no blood within the sheath, and the cord was healthy. The confession of the criminals themselves showed that these injuries to the spine were produced after death. (Kefer to pp. 253-4.) CHARACTERS OF INCISED WOUNDS. 259 The difficulty which in some cases exists in determining whether a bruise was inflicted during life or soon after death, will be greatly in- creased, it" the body we are called upon to examine is in a state of putre- faction. For the effect of putrefaction is to exaggerate the appearances of injury, and to produce alterations of consistence and colour, which would make it very difficult indeed to answer this question satisfactorily. It should also be borne in mind that when putrefaction sets in, the pres- sure of the gases evolved in the putrefactive process on the large veins of the body may cause copious outpourings of blood through ruptured vessels. This was well shown in the body of a man who had died of apoplexy. The veins of both arms had been opened, but no blood had flowed during life. After death, however, an abundant outpouring of blood took place from the wounded vessels. In a case, however, which occurred at Paris, the effusion of blood caused by strangulation was discovered as a black mass twenty years after death. But the cord was found round the neck, and removed all the difficulty which might otherwise have existed. In respect to fractures the same observations apply, and in nearly the same degree, as to contusions affecting the surface of the body. There is every reason to believe, that a fracture produced within a short period after death, and one produced during life, but speedily followed by death, would present very nearly the same appearances. A fracture produced some time before death would be readily distin- guished by the inflammation set up about it. Fractures, from the very nature of the parts injured, may be detected long after death. Thus, in the body of Clarke, the victim of Eugene Aram, the fracture and indentation of the temporal bone were plainly distinguished on the exhumation of the skeleton after it had been buried thirteen years. 2. CHARACTERS OP INCISED WOUNDS, AND THOSE ACCOMPANIED WITH A SOLUTION OF CONTINUITY, Under this head are comprised incised, punctured, and lacerated wovinds. Gun-shot wounds will be treated of separately. It is to in- cised wounds, as being of most frequent occurrence, that the following observations chiefly apply. The immediate and most obvious consequences of wounds with solu- tion of continuity are haemorrhage, and retraction of the edges of the wound: the more remote effect inflammation. In a recent incised wound, inflicted during life, there is copious haemorrhage, the cellular tissue is filled with blood, there are coagula between the lips of the wound, and the edges are everted. After the lapse of from eighteen to twenty-four hours there are the signs of inflammation, increased redness, swelling, and effusion of coagulable lymph. Copious haemorrhage affords of itself a strong presumption in favour of a wound having been inflicted during life, especially if the body is 260 WOUNDS. fresh. Scanty liaemorrhage, or the entire absence of it, as in the c^e of Sir Edmun'dbury Godfrey (p. 248), supplies an equally strong reason for attributing death to some other cause. Lacerated wounds, and severe gun-shot wounds, however, form an exception to this rule. In the well-known instance recorded by Cheselden of a man's arm torn off by a windmill, and in a case more recently reported by Mr. Bransby Cooper, there was little or no hemorrhage. On the other hand, a very considerable amount of haemorrhage may take place after death, and especially when putrefaction is set up, if any large vein happen to be wounded. In the case of incised, as of contused wounds, it is important to determine whether the same appearances that exist in Avounds inflicted during life may be produced after death. Characters of Wounds produced after Death. — The experiments of Orfila on the dog have shown, that the appearances proper to incised wounds inflicted during life may be produced immediately after death ; and the experiments of Dr. Alfred Taylor made on limbs recently removed by amputation, show to what degree the resemblance may be carried. After ten minutes there was immediate considerable retraction of the skin, with protrusion of the adipose substance, and the escape of a small quantity of blood ; and after the lapse of twenty-four hours, the edges were found red, bloody, and everted ; the skin somewhat flaccid ; a small quantity of blood escaped on separating the edges ; no coagula were found adhering to the muscles ; but at the bottom of the wound there were several loose coagula readily broken down by the finger. After the same interval of ten minutes a second experiment was perfonned. In this instance the edges of the wound were but very slightly evei'ted ; scarcely any blood escaped ; and twenty-four hours afterwards the edges of the incision were pale and perfectly collapsed, presenting none of the characters of a wound inflicted during life ; and at the bottom of the wound there were a few coagula of blood. Other experiments performed at a later period after the removal of the limbs gave rise to appearances less distinctly marked. When the wound was not made till two or three hours after the removal of the limb, a small quantity of liquid blood was effused, and no clots were found. The edges of an incised wound made twenty-four hours after death were yielding, inelastic, in close approximation, and free from any coagula of blood. Such are the characters of incised wounds inflicted after death. Lacerated wounds combine the characters of incised and contused wounds, being accompanied with a less amount of ha;morrhage than the foi-mer, and some degree of the discolouration attending the latter. For these reasons the distinction between such wounds inflicted during life and after death is less easily made. Punctured wounds are intermediate between incised and lacerated wounds, resembling the former when inflicted with a sharp instru- CHARACTERS OF GUN-SHOT WOUNDS. 261 ment, and being accompanied by profuse haemorrhage ; but when made with a blunt object, being more nearly allied to lacerated wounds, and productive of but little loss of blood. Sword -wounds, traversing the body, are marked by a large depressed orifice of entrance, and a small and raised orifice of exit. 3. CHARACTERS OF GUN-SHOT WOUNDS. Gun-shot wounds belong to the class of contused or lacerated wounds ; of contused wounds when the shot does not penetrate, of lacerated wounds when it enters or traverses the body. Such wounds, as Wiseman observes, are " the most complicate sort of wounds ;" they combine " contusion, attrition, and dilaceration " in a high degree ; they occasion "all sorts of fractures;" they introduce extraneous bodies ; and they give rise to haemorrhage, inflammation, erysipelas, gangrene, and sphacelus. The lips of a gun-shot wound are " livid or blackish ;" they become the seat of inflammation and swelling ; and " blisters frequently rise about them," containing " matter of a fcetid smell." Gun-shot wounds produced by discharges close to the person are " burnt by the flame," and they may contain particles of unconsumed powder. If covered by clothes, the clothes also may be blackened oi- burnt. As a general rule gun-shot wounds, unless they injure some large vessel, do not give rise to much haemorrhage ; but the destruction of parts occasioned by the sloughing and suppuration that follow upon them often occasions profuse and fatal discharges of blood. The bullet, shot, or wadding discharged from guns or pistols at short distances sometimes lodge in the body ; in other cases they traverse it. When they lodge in the body they often furnish very conclusive evidence. The bullet may prove to have been cast in a mould, or the wadding to be formed by printed paper or other ma- terial, in the possession of the person who fired the shot. It may even happen that the composition of the bullet, or the mode of making it, is peculiar. In medico-legal cases, therefore, the contents of a gun-shot wound should be carefully examined, and, if necessary, preserved. When bullets discharged from fire-arms traverse the body, the apertures of entrance and exit should be carefully examined. The aperture of entrance is round and clean, that of exit less regular in shape and jagged. On entering the body " the bullet forces the flesh in with it, and the place by which it enters presently contracts closer ; but its going out is more lax.'' The same difference of entrance and exit is seen in the clothes covering the wounded part. Bullets which strike the body obliquely produce a valvular wound. Bullets which lodge in the body are often found to have been turned out of their direct course by coming in contact with a bone, or other firm resisting structure. Thus (to give examples occurring in the practice of Richard Wiseman) a bullet which entered the cheek has 262 • wouKDS. been cut out from the back of the neck ; a second, which entered the outside of the small of the leg, was found on the inside of the thi^h above the knee ; and a third, which entered the outside of the arm, was cut out below the scapula. In some cases, the bullet has struck the head or abdomen, and after traversing the half-circumference of the part, has been found to be lodged, or to have passed out at, the opposite point. But a bullet may not only be turned from its straight course by encountering resistance, and being diverted into a less resisting channel, but it may be split into two or more fragments by striking a bone. These fragments may either traverse the body or lodge in it. If they lodge, they may be found to have taken the same eccentric course as the undivided bullet in the cases just cited : if they traverse the body they may occasion more than one wound of exit resembling in character wounds of exit caused by a single bullet. When the bullet takes a direct course through the body (that is to say, when it is not deflected) the character of the two apertures, coupled "with the direction of the line which joins them, may furnish important information as to the position of the body at the time the wound was received. So also when a bullet, after traversing an obstacle external to the body, such as wooden palings, or windows, strikes a wall beyond, the line of flight, and spot from which the shot was fired, may be readily determined. Small shot discharged quite close to the body, and striking it at right angles, may give rise to a round clean wound not easily distinguished from one caused by a bullet ; but at the distance of a foot or more the shot are found to scatter more or less, and to occasion an irregular wound. At the distance of three feet the shot are so much scattered that it is not possible to confound the injury with one caused by a bullet. In this class of wounds, we may always expect some of the shot to lodge in the body, and when fired close, or within a short dis- tance, there will be the same marks of burning on the skin and clothing. Fire-arms loaded with wadding, and fired quite close to the body, or within a few inches, may produce severe penetrating wounds, and destroy life, and even at the distance of a foot may give rise to severe and extensive superficial injuries. The unconsumed powder, when fire- arms loaded only with powder are discharged close to the body, may produce the same injuries as small shot. From what has been said above of the complicated character of gun-shot wounds, it is obvious that they are attended with great danger to life. They may prove fatal, immediately, or within a short interval, by shock or haemorrhage, and after a longer interval, by secondary haemorrhage, by erysipelas, by tetanus, or by the inflamma- tion and extensive suppuration following on the death of the injured parts. The usual medico-legal questions, such as the more or less danger- ous character of the wound, the effect of the treatment adopted, and of DETECTION OF SPOTS OF BLOOD. 268 the subsequent conduct of the wounded person, on the issue of the injury, and the amount of locomotion possible after the injury, arise in gun-shot as in other wounds. The question whether the wound was the result of accident, suicide, or homicide may also be raised respecting these in common with other wounds. As a general rule, accidental wounds, whether inflicted by the wounded person, in loading, or in the act of carrying a loaded piece, or by another person pointing at him a piece supposed not to be loaded, or walking or shooting in his company, have the characters of wounds caused by discharges near the person ; but these characters they have in common with suicidal wounds. But suicidal wounds have the character which accidental wounds often, and homicidal wounds, sometimes, lack of being inflicted in front on the head or region of the heart. To this rule, however, some suicidal gun-shot wounds form an exception, inasmuch as the weapon is directed to the back of the head. As a general rule, too, the suicide fires only one shot ; but to this rule, also, there are exceptions, for suicides have been known to fire two pistols, and even to resort to flie-arms after the failure of incised wounds. In some cases we are assisted by finding the suicide in a I'oom secured from within, with the weapon still grasped in the hand, and, when the priming was of powder, with the hand stained by it. Some advantage is occasionally derived from an examination of the gun or pi?tol. In all cases where the combustion of the gunpowder is imperfect, the finger introduced into the barrel is blackened by the unconsumed charcoal ; and on examining the residue it is found to consist of this unconsumed charcoal mixed with sulphuret of potassium. But where the combustion is perfect the finger is not blackened, for the residue is white and consists of the sulphate and carbonate of potash. After an interval of some days, varying with the more or less amount of moisture in the atmosphere, the mixed residue of charcoal and sul- phuret of potassium becomes converted into sulphate of potash, which after a still longer interval may be found blended with the rust of iron. 4. DETECTION OF SPOTS OF BLOOD. The medical jurist may be required to examine red spots supposed to be caused by blood on wearing apparel, on catting instruments, and on wooden floors or furniture ; also, in some cases, to examine solu- tions of blood in water. He may also be required to distinguish human blood from the blood of animals. Where spots of blood are recent, and the quantity of blood is con- siderable, the appearances which they present are highly characteristic, and there is no difficulty in obtaining a solution of a peculiar colour, readily distinguished from all other red fluids by its chemical and microscopical properties. But when the spots are not recent, and the quantity of blood is inconsiderable, the work of identification is less easy. ®0 264 WOUNDS. Blood is a compound fluid, consisting of fibrin, serum, and a colouring matter known as hcematosine, which colouring matter is contained in the circular discs or red corpuscles figured in the annexed woodcut, ^ The fibrin coagulates spontane- ously ; the serum is coagulated by heat or acids ; the red corpuscles are visible under the higher powers <^ of the microscope ; and the colour- [^^ ing matter has some peculiar and characteristic chemical reactions. Magnified 400 diameters. ^pj^e red corpuscles, or globules, of the blood are seen under the microscope as isolated discs, either a in plan, or b in profile ; or c aggre- gated like piles of coin ; or d variously contracted and crimped by the exudation of their contents. The colouring matter of blood-stains is more or less completely dis- solved out by cold water ; and the blood-solution thus obtained has a vei-milion red colour. This colour is discharged, and the solution changed to a dirty slate colour by boiling, at the same time that the serum is coagulated, and thrown down. This coagulum, if collected, dried, and boiled in liquor potasses is completely dissolved, forming a dark-green solution. The blood-solution has also the characteristic property of not being changed in colour by the addition of a small quantity of liquor ammonia; . With infusion or tincture of galls the blood-solution yields a red precipitate. These tests are quite chai"ac- teristic. No other red solution has the same reactions. Those ob-^ tained from flowers and roots and the juices of fruits are changed to green or violet by liquor ammoniae, and cochineal to crimson. The solution of sulpho-cyanide of iron yields a precipitate of oxide of iron, and is rendered colourless by zinc and sulphuric acid, and permanganate of potash is changed from pink to blue ; and none of these colouring matters are coagulated and changed by heat. Ked coloui-ing matters due to the presence of salts of iron yield a dark-blue precipitate with the infusion or tincture of galls. Blood-stains on articles of dress may be recognized by their con- sistence and colour, and more completely identified by microscopic examination. A spot of blood not disturbed by contact or friction feels like thick gum or starch. Small spots are circular, larger spots approach the circular form, and large and small alike have a defined and abrupt margin. Arterial blood has at first a rich red colour, and venous blood a purple hue. Venous blood first grows brighter by ex- posure to the air, but, after a time, in common with ai-terial blood, assumes a venous tint. After the lapse of a few hours, the blood, whether from an artery or vein, assumes a dusky blue colour, which it retains without change for years. Blood-stains on white calico up- wards of twenty years' old have undergone no perceptible change. BLOOD-STAINS ON ARTICLES OF DEESS. 265 The colouring matter of these stains may be procured for examina- tion in the following manner. The stained fragment of cloth is to be cut out, placed in a test-tube with a small quantity of cold distilled water, and shaken for a few minutes. A recent stain so treated may yield a red, or reddish-brown solution, of a sufficient depth of colour to give characteristic results with liq. ammouise and on boiling. But older stains give up their colour very slowly and imperfectly, whether suspended in distilled water, as usually recommended, or agitated with water in a test-tube ; and the process is not much hastened by separat- ing the fibres of the cloth. For these older stains, therefore, a different process is required. The stain is to be moistened with a few drops of distilled water, and scraped with a scalpel or sharp knife. To the small quantity of coloured liquid thus obtained a drop or two of glycerine or syrup is to be added. The resulting liquid, placed on a glass slide and covered with a piece of microscopic glass, will be found to contain the red corpuscles figured at p. 264, mixed with a few fibres from the cloth. Stains on white calico upwards of twenty years old have yielded highly characteristic results when treated m this way. Blood-stains on articles of linen or cotton may be shown to contain animal matter by placing them in a reduction-tube, applying the flame of a spirit-lamp, and exposing a moistened slip of turmeric paper to the gases which issue from the tube. The presence of ammonia is shown by the usual change of colour from yellow to brown. The colour and appearance of the stain, confirmed by this test, leave no room to doubt that the stain was^ caused by blood. This test is not applicable to silken or woollen textures. Another, and very ingenious, test for blood-stains has been suggested and practised by my friend and colleague Professor Bloxam. It is founded upon the well-known fact that coagulated albumen becomes soluble in water at about the temperature of boiling oil (350"-* Fahr.). The stain is introduced into a strong tube of green glass sealed at one end, moistened by from half a drachm to a drachm of distilled water, and secured by sealing the open end of the tube. The tube, so sealed at either end as to bear strong pressure from within, is now placed in a small iron saucepan containing oil, which is kept boiling for the space of an hour, at the end of which time, the contents of the tube will be found to have acquired a dirty slate colour, and the stain to have parted with some of its colouring matter to the distilled water. The dis- coloured water, on being tested with nitric acid, bichloride of mer- cury, and ferrocyanidu of potassium, will yield the white precipitates characteristic of the presence of albumen. There is still another test for blood-stains recommended by Virchow as " one of the surest tests " as. well as a most delicate one; and it is one of which he has practical experience in medico-legal cases. It is based on the production of minute crystals of Hcemine. The blood- stain is to be covered with dry, crystalline, powdered common salt, 266 WOUNDS. ^^r / moistened with glacial acetic acid, and evaporated at a boiling heat. 'I'he dry residue contains crystals of haemine in large numbers. By this method Virchow was able to pro- •^'^' ^^" duce innumerable microscopic crystals 1 z from a blood-spot a line in dia- I meter. These crystals are represented • 3^' in fig. 10. The larger ones (1) are \//^ after Virchow, the smaller ones (2) \ j) are copied from the result of an ex- periment on aminute recent clot of 300 diameters. 150 diameters, sheep's blood. With blood-stains of long standing this test fails, though the stain on the glass is of a veiy characteristic colour. Iron-moulds on linen have sometimes, as in a case lelated by Devergie, been mistaken for spots of blood ; but the distinction is easily made. Cold water dissolves out the colouring matter of blood more or less quickly and completely ; but it does not affect the ii on-mould. Hydro- chloric acid dissolves out the iron, which may be identified by its characteristic tests. Blood-stains on floors and furniture may be identified in the manner just recommended. The stained portion of wood should be cut out, moistened with distilled water and scraped ; or the small clot of blood may be carefully detached and placed in distilled water. Bloodstains on articles of steel and iron are readily identified when they present themselves in the forai of clots on a clean bright surface of metal. They are then of a clear red, or reddish-brown colour, are easily detached, and scale off when the metal is exposed to a moderate heat. The presence of animal matter in the spots is readily ascer- tained by heating them with the spirit lamp in a reduction-tube. Ammonia is given off, which is detected by its alkaline reaction on turmeric paper. A small particle of blood-crust is sufficient for this purpose. The crust placed in a iew drops of distilled water will, after a time, yield a reddish-brown solution with the reactions already described ; and if treated with syrup or glycerine, and placed under the microscope, will be found to contain blood-globules. If the blood is merely smeared upon the instrument it will not scale off when heated ; but it will be necessary to moisten the stain with dis- tilled water, and scrape it off carefully for examination by tests or the microscope. If the instrument has been for some time exposed to air and moisture, spots of rust will be mixed with those of blood. In this case, too, the stains are not detached by heat, and it will be necessary to scrape them off, place them in distilled water, and separate the insoluble par- ticles of rust by filtration. The resuUing coloured liquid will have the chemical and microscopic characters of the blood solution. Two other kinds of spots on articles of steel or irori have been pointed out as liable to be mistaken for spot* of blood, namely, spots of DIFFERENCE BETWEEN BLOOD OF MAN AND ANIMALS. 267 rust and spots produced by lemon-juice, vinegar, or other vegetable acid. Spots of Bust somewhat resemble blood-spots in colour, but they do not scale off on the application of heat, and they are not solable in water. If thick enough to be detached, they are readily separated by filtration, leaving the water quite clear, and not atfected by the tests for iron. A drop of hydrochloric acid placed on the spot of rust dis- solves it, and leaves the metal clean, and on diluting the solution with distilled v/ater, evidence of the existence of iron may be obtained by appropriate tests. Spots of Lemon-juice have b^n mistaken for those of blood. A man, as in a case related by Orfila, was suspected of having murdered another, and a knife, apparently covered with blood, was found in his possession ; but on submitting the knife to examination, it was found that the spots were due to citric acid. The instrument had been used some days before for cutting a lemon, and had been put by w^ithout being wiped. The thinner spots produced in this way have a reddish-yellow colour. The thicker spots have a reddish-brown colour, nearly re- sembling that of blood, and they separate, like blood-spots, on the application of a moderate heat. When heated in a tube they give off a volatile matter, which has an acid reaction — spots of blood have an alkaline reaction. The solution in distilled water is light yellow^- that of blood is red ; it sometimes has an acid reaction — that of blood is neutral, or faintly alkaline ; with infusion of galls it yields a black precipitate, a blue with ferrocyanate of potash, and a rich cherry red with the sulpho-cyanide of potassium. Blood yields a red precipitate with the first test, and is unaffected by the others. The oxide of iron is thrown down by alkalis. Supposing it to be clearly made out that the stain we have been examining is a blood-stain, two questions may arise: 1. Is it human blood, or that of an animal ? 2. From what part of the body does the blood flow ? 1. Difference between the blood of man and that of animals. — Two means of diagnosis have been proposed, the one microscopic, the other chemical. Diagnosis by the microscope. — The only means of distinction under the microscope is afforded by certain well-known differences in the shape and size of the blood-corpuscles. The human blood-corpuscle, depicted in fig. 9, p. 264, is a circular flattened disc ; and the blood corpuscle of mammals, with a single unimportant exception, has the same form. The only appreciable difference is in the size of the globules. In man they measure on an average gJg^ of an inch ; in animals the diameters vary from jJjjj to gj'gg. But these are only averages ; and the extreme measurements which in man may be stated at ^uVo ^nd ^'^j, lie, in some animals, still wider apart. When it is borne in mind that, in most instances, we have to examine a blood-solution obtained from 268 WOUNDS. dried blood, made to approximate to the average density of the blood by the addition of syrup, glycerine, or a saline solution'; that the size of the globules is materially affected by the density of the medium in which they are seen ; and that in the blood itself the diameter of one globule may be twice as great as that of ai\other, it is not to be ex- pected that the most skilful and practised person should be able to distinguish human blood from that of other mammals. But the blood-corpuscles of birds, reptiles, and fishes differ so widely in size and shape from those of man and animals, as to enable us to state positively that the blood in a given case is either that of a mammal, or belongs to one of the three classes of creatures just specified. The differences of size and shape in the human blood (1), the blood of the common fowl ; (2), the blood of the frog; (3), and the blood of a fish, (4), are shown in the annexed engraving. The corpuscles are mag- nified about four hundred diameters. Fig. 11. <^ (For some minute details of measurements in Mammalia, see 'Micro- graphic Dictionary,' Art. Blood; also Plate 40.) Chemical Diagnosis. — It was Barruel who first proposed to dis- tinguish the blood of different animals by the characteristic odour given off on the addition of sulphuric acid. If sulphuric acid, diluted with half its bulk of water, is added to the blood of an animal, an odour is instantly perceived which certainly bears a close resemblance to the perspiration of the animal itself; and it is probable that the majority of persons would recognize the odour if informed of its existence. But it is certain that the majority would be mistaken if asked to name the animal which had supplied the blood. I make this statement as the result of experiments made with fresh blood of different animals, in such quantity as one or two drac>.hms at a time, in the class-room for several years in succession. The majority have always been wrong in their guesses. At the same time it should be stated, that, on one occasion, a member of my class was uniformly right in his opinion of several specimens of blood, though the experi- ment was so devised as to preclude mere guessing. As a means of distinguishing spots of blood, or solutions obtained from them, this test of odour must certainly be disallowed. It has also utterly failed in the hands of very competent persons. Source of the blood. — la some cases the spots of blood submitted for QUESTIONS COMMON TO ALL WOUNDS. 269 examination are found blended with hair, skin, fragments of mucous membrane, or epithelial cells ; or with other matters adhering to the material upon which the blood has fallen. The discovery of such ad- mixtures may often supply very important medico-legal information ; but the subject is one of too great extent to be fully examined in this place. Such examinations as these should always be intrusted to persons having perfect knowledge of the microscope, and large experi- ence in the use of the instrument. 5. THE QUESTIONS COMMON TO ALL FORMS OF MECHANICAL INJURY. There are three questions common to all forms of mechanical injury ; namely, 1. Was the injury inflicted during life? 2. Was it the cause of death? and 3. Was it accidental, suicidal, or homicidal ? The first question has been already examined. The second and third questions still remain to be discussed. Was the Wound the cause of Death f — ^The answer to this question i-arely presents any difficulty when a man in the enjoyment of perfect health receives a severe injury, and dies soon after, before sufficient time has elapsed for disease to set in, or neglect, or unskilful treatment to prove injurious ; before, in fact, any event has supervened to com- plicate the original question proposed. But when a considerable interval elapses between the receipt of the injury and the fatal event, such com- plications may arise, and render the answer to the question difficult. The question — Was the wound the cause of death ? may have to be decided in cases in which the fatal result follows soon after the receipt of the injury, as well as in cases in which the death happens at ah in- terval so remote as to admit of the supervention of extianeous causes. To the first class of cases belong the abnormal formation of the parts injured (as in the instance cited by Paris and Fonblanque, of the death of a boy caught robbing an orchard, caused by a blow intended as a simple chastisement on a skull preternaturally thin), and their ab- normal situation (as in the familiar instances of an inguinal hernia, injured by a kick ; of fatal haemorrhage caused by a blow on the loins over the seat of a kidney containing a jagged calculus ; and of a large abscess behind the ear ruptured by the same means). To this class of cases also belong those sudden deaths which follow falls or blows too slight to account for the fatal result by the direct injury they occasion, death being really caused by the effusion of blood upon the brain, or the rupture of an aneurism ; in both which cases it is possible to atti-ibute the death to the excitement of the struggle as well as to the fall or blow. Also those cases of latent effusion on the brain or into the cavities of the chest which might prove suddenly fatal even in the absence of violence, but which might certainly cause death under the influence of excitement or shock. 270 WOUNDS. In such cases as these the injury is inflicted in ignorance of the existence of any cause by which that injuiy, though comparatively slight, might be rendered mortal. To all other cases, such as those of young, feeble, or aged persons, and pregnant women, the English law, as laid down by Lord Hale, will apply : *' It is sufficient to prove that the death of the party was accelerated by the malicious act of the prisoner, although the foimer laboured under a. mortal disease at the time of the accident." The second class of cases, or those in which an interval elapses before the wound proves mortal, comprises a greater number of special cases. Before treating of these cases in detail, it is necessary to premise that even when the interval between the injury and the fatal result is of considerable duration, it may be quite possible to attribute the death to the injury without any misgiving. The injury may be of such a kind that no strength of constitution, and no exercise of care and skill, could avert a fatal termination. In fractures or dislocations of the spine, for instance, and in gun-shot wounds when the bullet lodges in the body, however long the fatal result may be postponed, the death is fairly attributable to the injury alone. But though, in cases of this kind, no doubt can exist either respecting the true cause of death, or the guilt attaching to the act of violence, the lapse of time has, in most civilized countries, been taken into account, and by the common law of England, if the injured party survive one year and one day, the crime ceases to be murder, and English juries have sometimes shown a disposition to shorten this period very considerably. Within this long period of 366 days there is ample opportunity for some of the circumstances now to be specified to come into play. 1. A trifling wound or injury may prove fatal, from the injured part taking on an unhealthy character, such as scrofulous inflammation, due to peculiarity of constitution, or from the supervention of some disease not necessarily or usually resulting from it, such as eiysipelas. 2. To the same class of cases belong instances of fatal tetanus, or of delirium tremens from slight injuries, as well as rare instances of pyajmia from latent abscess brought into activity by a fall or blow, and instances of fatal diseases of internal organs springing up independent of the injury but soon after its occurrence. 3. Another circumstance bearing on the question, Was the wound the cause of death ? is the improper management of the wounded party, whether consisting in the neglect of medical assistance, or of medical instructions, or in the resort to ignorant and unqualified practitioners, or in irregularities, misgovemment, and reckless exposure to cold, fatigue, or fiesh injury, or to intoxication, on the part of the patient himself, or in mala praxis on the part of the medical attendant, being a qualified practitioner. Was the wound accidental, suicidal, or homicidal^ — Accidental death is a common occurrence in crowds, and in wrestlings and fights, when the deceased person falls, or is thrown or struck against, NATURE OF THE WOUND. 271 hard resisting objects, in which case an examination of the spot on which the party fell will help to determine the question. There is always a probability of accident when a body is found in a dangerous situation, as at the foot of a precipice, or in a river with steep banks ; and the probability is increased when the deceased person is proved to have been drinking previously. In all doubtful cases the character of the injuries found on the body will go far to detei'mine the class to which the death belongs. Bruises, fractures, and dislocations, for instance, are more consistent with the theory of death by accident than incised, punctured, or lacerated wounds. If we suppose the alternative of accident to be excluded by the nature of the case, the original question is narrowed to this, Was the injury suicidal or homicidal ? As suicides are much more common than homicides, there is always a primd-facie probability in favour of suicide, especially in middle- aged persons ; but this probability will be materially modified by such considerations as, the place in which the body is found ; the nature, situation, extent, and direction of the wound ; and the number of wounds. The Place where the Body is found. — If a corpse is found in a room with the windows and doors fastened on the inside, the circumstances are conclusive as to suicide. The absence of the instrument of death would be conclusive as to murder. So also, if the blood from a mortal wound has been washed from the body or floor, or the body itself has been placed in a position inconsistent with the mode of death, or covered, or buried. The Nature of the Wound. — Contused wounds are rarely suicidal, though attempts at self-destruction by knocking the head against the wall are not uncommon. Severe contusions, therefore, are most pro- bably homicidal, unless the body is lying near a height from which it might have fallen accidentally, or from which the deceased might have thrown himself. Incised wounds are as likely to be suicidal as homi- cidal, and it is not often that the peculiarity of the wound affords us any assistance in determining the class to which it ought to be re- ferred. The cleanness and evenness of an incised wound have, indeed, been mentioned as affording a probability in favour of homicide. It is generally asserted, that a self-inflicted wound is likely to be jagged and uneven ; but this assertion does not seem to be borne out by reason- ing or by fact ; for a suicide who has made up his mind is less likely to waver in his resolution than a man to remain still under the hands of a murderer; and some of the deepest and cleanest wounds of the throat are certainly suicidal. But in some few instances the shape of an incised wound does afford very important aid in determining the question of suicide or homicide, by pointing out the kind of instrument with which the wound was inflicted, and the occupation of the murderer. Thus, a man found with his throat cut from within to without, as butchers slaughter 272 WOUNDS. sheep, was found to have been murdered by a butcher. Orfila cites the case of a murder traced to a butcher by the fact of the body being found divided into two parts by a cutting instrument passed into the fibro-cartilage uniting the third and fourth himbar vertebrae, and dividing the articulating processes of the vertebraj transversely through, as butchers ai'e accustomed to cut through the spines of animals. The Situation of the Wound. — It may be laid down as a general rule, that if a wound is so situated that the instrument of death, when placed in the hand of the deceased, cannot be made to reach it, whether by the motion of the hand itself, or by that of the part injured, or by both jointly, it was not self-inflicted. Wounds inflicted on concealed y)arts of the person, as within the labia, and beneath the breast of the female, are in all probability homicidal. It must, however, be borne in mind that while murderers sometimes inflict injuries of a kind to appear suicidal, many suicides are moved by very eccentric impulses. The Extent of the Wound. — It has been thought that a suicide would not have courage or strength to inflict a very extensive wound upon himself; but eiq^erience is opposed to this view. Suicidal wounds of the throat, for instance, are usually deep and extensive ; and in newspaper accounts of cases of suicide nothing is more common than to read of the head being nearly sevei-ed from the body. Super- ficial wounds of the throat are, however, among the most common forms of pretended suicide. The Direction of the Wound. — Suicidal wounds generally pass from left to right, and from above to below, such being the most natural movement of the arm. In the case of left-handed persons, the direction would be from right to left. Wounds of the throat, whether suicidal or homicidal, are, however, generally transverse. When persons of different statures fight together, it is natural to suppose, that a wound inflicted by the taller man would pass from above downwards, and the reverse if given by the shorter, supposing both combatants to be in the erect posture. In wounds inflicted by a sword, or by fire-arms, it is always important to notice both the direction of the wound, and the orifices of entrance and exit. The Number of Wounds. — The coexistence of several mortal wounds affords a presumption against suicide, but only a presumption ; for after inflicting on themselves wounds necessarily mortal, suicides have retained strength and determination enough left to inflict others. Thus Orfila relates the case of a gentleman at Rouen who was found dead in his chamber, with two pistols lying in the room, one near the body . the other on the bed, at some distance from it. The deceased had shot himself in two places. One wound, apparently inflicted while he was lying on the bed, had completely traversed the left side of the chest, breaking a rib before and behind, perforating the lung through its middle portion, and passing near to the roots of the pulmonary veins. A very large quantity of blood was extravasated in the thorax. IS THE WOUND DANGEROUS TO LIFE? 273 After inflicting on himself this serious injury, the deceased must have risen from his bed, walked to a closet to procure another pistol, with which he produced a second wound that must have proved instantly mortal. Thi> ball had entered at the frontal bone, and, after tra- versing the left hemisphere of the brain, had become lodged against the OS occipitis. There was not the least doubt of this having been an act of deliberate suicide. Mr. Watson gives a case of suicide in which no less than ten wounds were inflicted on the throat. It is scarcely necessary to observe that most of the probabilities just established are liable to lead to error if too implicitly relied upon. In inquiring into the true manner of death in doubtful cases we have to guard against false inferences from circumstances purely accidental as well as from arrangements made to deceive us. Nor will it always be safe to assume that a severe injury, actually inflicted by another, is the real cause of death ; for as in a case related by Wildberg, a death occurring during a chastisement may, on examination, be found to have been due to poison. The circumstantial evidence in death by wounds is of the first im- portance. It has been already alluded to under the head of persons found dead. Thus Sellis, a servant of the Duke of Cumberland, after- wards King of Hanover, was found lying dead on his bed with his throat cut, while his master was .under the care of Sir Everard Home severely wounded in the head and hand. His Royal Highness stated that he was roused from sleep by a blow on the head, followed by several others, one of which caused an immense effusion of blood ; that he leaped out of bed, and followed his assailant, who repeatedly struck at ' him, and would doubtless have murdered him, but that the doors pro- tected his person from some of the blows. Every part of this statement was confirmed by the circumstantial evidence. The coloured drapery at the head of the duke's bed was sprinkled with blood ; there were traces of blood on the passages and staircase, and on the doors of all the state apartments ; and ISellis's coat was found hanging on a chair out of reach of blood from his bed, but the sleeve was sprinkled from the shoulder to the wrist " with blood, quite dry, and evidently from a wounded artery." When Lord William Russell, the victim of Courvoisier, was found lying dead in his bed with his throat cut, the facts that the instrument of death did not lie near the body, and that a napkin was placed over the face, were in themselves conclusive as to the question of suicide or homicide; and left no doubt whatever that he had been barbarously murdered. Again, when a woman of the name of Norkott was found dead in her bed with her throat cut, the fact that, on the left hand of the deceased, there was a bloody mark of a left hand was conclusive evidence of her having perished by the hand of another. In addition to the questions already examined there are others which may have to be considered. We may be asked whether a T 274 WOUNDS. given wound is dangerous to life, and of many wounds which was mortal. Sometimes, too, it may be important to know how long the wounded person survived the injury, and to fix the point of time at which a wound was inflicted. These questions will now be briefly discussed. Ts the Wound dangerous to Life? — This question is easily answered in the case of injuries to the large blood-vessels and important viscera of the body, but less easily in the case of injuries which affect life rather by their extent than by the importance ol the pai-ts implicated; for while, on the one hand, slight injuries to parts altogether imim- portant may, in peculiar states of constitution, prove fatal, on the other hand, recovery may take place from injuries the most severe and extensive, as was the case of Mr. Tipper, who was pinned against a stable-door by the shaft of a gig traversing his chest. The question of the danger attending wounds or injuries of the several important parts of the body will be found discussed under the next heading. Of many Wounds which was mortal'? — It is easy to understand how this question may become important in a medico-legal point of view. A mortal struggle may begin with blows and end with the use of a stabbing or cutting instrument, and the crime would have a A'ei y different aspect, according as the death was attributable to the blows or to the stabs or cuts. The question is of so general a nature that it must suffice to indicate its importance. How long did the wounded person survive'? — This question, too, may evidently assume importance in a court of law, especially in con- 'nexion with the amount of exertion possible after severe injuries. But the question, as one of detail, can be answered only as in the next division. ■ When was the Wound inflicted ? — This question may arise either during life or after death. During life the question must be answered, in the case of contused wounds, by the extent of the ecchymosis and the colours it assumes ; in the cases of incised and punctured wounds, by the state of the divided parts, whether they ai-e filled with exlravasated blood or not; and whether the edges are swollen, and the surrounding skin inflamed. After death the question either resolves itself into the simple in- quiry. How long has the deceased been dead ? or into the double question of the date of the death and the length of time that the deceased sur- vived the injury. The presence or absence of animal heat, of cadaveric i-igidity and of putrefaction, and the progress which putre- faction may have made, must be taken into account. These changes in the condition of the dead body take place, as has been already observed (p. 212), with very different degrees of rapidity in different subjects ; so a? to oblige us to speak of the time occupied by them with caution and reserve. WOUNDS OF THE HEAD. 275 6. OF WOUNDS AS THEY AFFECT THE SEVERAL PARTS OF THE BODY. Some of the questions which have been merely indicated as im- portant in the previous division, will he examined in detail in this. Wounds of the Head. — Injuries to the saalp are of more import- ance than those of the integuments of other parts of the body, partly on account of the peculiar tendency of the skin itself to take on the erysipelatous inflammation, partly from the quantity of loose areolar tissue which intervenes between the tendon of the occipito frontalis and the periosteum, and which is very liable to become the seat of diffuse inflammation ; and partly from the relation of the tendon to this lax tissue, preventing, as it does, the escape of the effused pro- ducts. Punctured wounds of the scalp are dangerous on account of the inflammation which they set up in this tissue, and the want of free exit for the discharges. Contused wounds are also dangerous for the same reasons. On the other hand, extensive lacerated wounds which do not involve the periosteum are rarely productive of serious consequences, inasmuch as they afford free passage to the products of inflammation. Fractures of the Skull are not more important than those of other bones, unless they are accompanied by injury to the brain or its mem- branes. But in this case, as in that of wounds of the scalp, a slight injury may lead to fatal consequences, while complete recovery may take place after very extensive injury. The force that occasions the fracture may, at the same time, produce concussion, or other injury to the brain. It is important also to understand, that a blow does not always fracture the bone on which it alights, but that it may produce a counter fracture at an opposite part of the skull. A severe blow on the vertex of the head, for instance, will often occasion a fracture at the base of the skull, especially when applied at once to a large surface, as in a fall from a height. ,> In forming an estimate of the danger attending fractures of the •skull, it is necessary to bear in mind the different thickness of its several parts. Thus, a blow on the temple would be productive of greater injury than one of equal force applied to other parts of the cranium. The orbitar plate is another part which by its extreme thinness exposes the brain to serious injury from thrusts with pointed instruments. The cribriform plate of the ethmoid bone again would be easily fractured, and the base of the brain be readily injured by a sharp-pointed instrument thrust up the nostril. Injuries of the Brain itself will have to be considered under the distinct heads of concussion, compression, wounds, and inflammation. Concussion of the Brain. — This is a common effect of severe blows or violent shocks. The symptoms often follow immediately on the accident, and death takes place without reaction, or any improvement 276 WOUNDS. from the usual remedial means. In other cases the sj'mptoms of con - cusslon and compression are combined, and in others, again, concussion is followed by compression or inflammation. Several cases of death by concussion are on record in which no lesion of the brain could be discovered. Thus, Mr. Tiavers, in his work on * Constitutional Irritation,' gives the case of a prize-fighter who was taken off the ground insensible, and apparently apoplectic, and died in eight hours ; yet no lesion or extravasation could be discovered on careful inspection of the brain. The interval which elapses between the receipt of this form of injuiy, and the fatal termination is veiy various. It may prove fatal, as in the case just quoted, in a few hours, or after the lapse of several days, weeks, or even months. Thus Richard Wiseman, in his chapter on Wounds of the Head, gives the case of a lady who received a blow on the head while riding under a pent-house. The blow stunned her, and she died after many months of suffering from the injury with symptoms pointing to abscess of the brain. It is a remarkable circumstance connected with this class of injuries, that the patient sometimes seems to suffer little or no immediate incon- venience ; but, after the lapse of some days, is seized with symptoms of compression or of inflammation of the brain. Thus, Mr. Pott gires the case of a woman who received an injury on the head, and remained well for twelve days. She then fell ill, and died with symptoms of compression of the brain. The ventricles were found to contain bloody serum, and a small coagulum of blood. And Abercrombie gives the case of a girl, aged thirteen, who fell from a swing, and struck her head violently against the ground. For six weeks after the accident she complained of headache, but was not otherwise ill. Feverish symptoms then came on, followed by slight delirium and <;oma, and she died two months alter the fall. The ventricles were found distended with serous fluid, without any other morbid appearance. Compression of the Brain. — This may be caused by depressed bone, or by the effusion of blood or serum. The symptoms come on suddenly or gradually, according to the nature of the compressing cause, and the fatal result follows in varying intervals of time. In cases of com- pression produced by depressed bone, the cause of death is obvious, and can give rise to little difficulty ; but when it arises from effusion of blood or serum following an injury, it is easy to allege that the effusion and consequent fatal result were due, not to the injury itself, but to some concomitant circumstance. Thus, if in the course of a struggle a man is thrown down or struck, and dies soon after, with symptoms of compression, and it appears that an effusion of blood has taken place, the effusion may be attributed to the excitement of the contest, and not to the injury itself; and the question will be even more difficult if the deceased was given to habits of intoxication, or was of a plethoric habit, and apoplectic make, or of an advanced age. WOUNDS OF THE BRAIN. 277 The inquiry will be still more difficult, if on dissection the vessels of the brain are found in a diseased state ; but as effusion of blood rarely takes place on the surface of the brain from disease, the difficulty will only attach to effusions of blood at the base, in the ventricles, or into the substance of the organ. Wounds of the Brain. — This class of injuries presents considerable difficulty in a medico-legal point of view — a difficulty which cannot be better set forth than in the words of Richard Wiseman. He says that " the greater symptoms that are usually said to attend the wounds of the brain do show themselves more uncertainly than a speculative chirurgeon would imagine ; and in cuts and wounds made by sharp weapons or sudden strong force, more uncertainly than in contusions, concussions, and depressions of the skull ; the highest of them, viz., vomiting, stupor, loss of spirits, with a paralysis of legs and arms, arising more suddenly in these latter cases than in the former." " Nay, we see many die suddenly from a box on the ear, and from small blows or wounds. In some whereof, upon opening the cranium, there hath been much blood extravasated : in others none at all, or aught else that may be thought to have killed the patient." " Others I have been called on to see opened, when there had pi eceded only a contusion of the calvaria, without any fissure, or more extravasated blood than is usually seen in every opening on taking off the cranium : yet the patient lay, as I am informed, under all those symptoms of delirium, coma, &c. Then, again, I have drest many that had been cut through the skull, the shivers of bones lying pasht with the flesh and hair upon the dura mater : yet the patient hath been without any symptoms of such a wound ; which I suppose happened by reason of the bones lying loose upon the membrane." Of severe symptoms speedily supervening from a slight injury the following is an example. A young man received a blow on the fore- head from a cudgel, soon took to his bed and became delirious : a sopor followed, and after some days he died. A small hair-like fissure was found running from the great canthus of the eye upward. On removing the skull and dura mater but little blood was found extra- vasated, and the pia mater little altered. Of comparatively slight symptoms following very severe injuries, the following is an example of the opposite kind from the same author : A soldier was shot in the face by a case-shot, and had *' his face, with his eyes, nose, mouth, and forepart of the jaws, with the chin shot away, and the remaining parts of them driven in. One part of the jaw hung down by his throat, and the other part pushed into it. I saw the brain working out underneath the lacerated scalp on both sides between his eyes and bix)ws." Yet this man, after being carried off as dead, was found next morning knocking against the door of the r;jom in which he had been placed, and was seen standing by the door. He was quite sensible, implored help by signs, and assisted himself to drink. His wounds were dressed, and he remained under Wiseman's care six or 278 WOUNDS. seven days, beincj left alive at the end of that time. An equally re- markable case, illustrating the power of locomotion that may remain after very severe iiij ii'ies of the brain, is related in the voyages of the great French surgeon, Ambrose Pare. ** A soldier in my presence gave to one of his fellows a stroke with an halbard upon the head, penetrating even to the left ventricle of the brain, without falling to the ground." After being dressed by Pare " he letumed all alone to his lodgings, which was at least 200 paces distant." The third day he came staggering to Pare"s tent to be dressed, but died under his hands in a convulsion. Pard says : " I have recited this history as a monstrous thing, that the soldier fell not to the ground when he had received this great stroke, and was in good senses even till ileath." Other remarkable cases of the same kind are to be found in the works both of Pare' and Wiseman. Many modern cases might also be cited, but the following will suffice. Thomas Fothergill was charged before Mr. Justice Willes at Newcastle with the wilful murder of John Smith. The prisoner struck the deceased on the head with a pickaxe. The blow knocked him down, and then the prisoner struck him again with the pickaxe on the body. The deceased was lifted up by a fellow- workman, and after a time was able to walk to his lodgings, from which he was conducted to the Newcastle Infirmary, where he died ten days afterwards of the injuries he had received. On examination it appeared that he had received a wound on the temporal bone, which had driven it in and had lacerated the brain ; and the spleen was also found to be torn by external injury. Either injury was sufficient to cause death. Inflammation of the Brain. — Inflammation of the brain may follow upon injuries, not only to the organ itself, but to the scalp, and the parts most nearly connected with the brain, such as the orbit and ear. The severity of the inflammation is not always proportioned to the injury received. A slight injury may give rise to very severe inflam- mation, a severe injury to very slight effects. The period at which inflammation sets in is also very variable. As a general rule, it does not follow directly upon the injury, but several hours, some days, or even weeks may elapse before it takes jjlace. Injuries of the head, then, have this peculiarity, that at first they often appear of little consequence, but after a considerable interval dangerous symptoms may arise and prove fatal. Railway accidents have more than once given rise to difficult questions relating to this class of injuries. The symptoms of injury to the nervous system have not shown themselves at once, but the following day, or after a still longer interval, and much difficulty has been experienced by the jury in awarding damages, in consequence of conflictiug medical opinions. In the interval which elapses between the receipt of the injury and the accession of dangerous symptoms, there is always room for neglect or mismanagement, on the part of the patient, his friends, or the medical WOUNDS OF THE THROAT. 279 attendant, which may materially affect the question, — Was the injury the cause of death ? This question, therefore, has a peculiar application to injuries of the head. Injuries to the Spinal Cord. — The spinal cord, like the brain itself, is subject to concussion ; to compression, from effusion of blood on its surface or in its substance ; and to wounds from fractured vertebra^. Concussion and compression may follow severe shocks, as in railway accidents ; the more severe injuries arise from falls or blows, or sudden twisting movements of the neck. Injuries to the substance of the cord generally prove fatal, the interval varying according to the degree of violence used and the part of the spine which has been Avounded. Serious injury to the upper part of the cord proves imme- diately or speedily fatal by paralyzing the muscles of respiration ; injuries to the cord opposite the lower cervical vertebrai (the fourth, fifth, sixth, and seventh) prove fatal in from four or five hours to as many weeks or months : in rare instances not till the lapse of years. In the case of John Carter of Coggeshill in Essex, displacement of the last three vertebrae with pressure on the cord opposite the seventh vertebra, did not prove fatal for fourteen years. When the cord is injured in the dorsal or lumbar region there is loss of power and sensation in the parts below the seat of injury with retention of urine and loss of power in the sphincter ani, requiiing constant medical aid and careful nursing. With these aids life may be prolonged for years. Many injuries to the brain principally affect its base, and by- causing pressure on the medulla oblongata impair the functions of the nerves supplying the muscles of respiration* Wounds of the Face. — These injuries obviously produce great dis- figurement, and, in consequence of the large distribution of important nerves over the face, still more grave inconvenience. From the near proximity of the principal features to the brain, there is also a risk of injury to that organ, as well as of inflammation extending from the seat of the wound. In this respect the wounds of the integuments of the face rank next in importance to those affecting the scalp. Wounds of the Throat. — These injuries are important from their frequency. They are the chosen mode of death with a gieat majority of suicides, and sometimes a murderer inflicts a wound on the same part in the hope that his victim will be supposed to have committed suicide. The degree of danger depends upon the position and the parts implicated. Wounds of the anterior part of the throat are less dan- gerous than those of the side of the neck ; those of the lower part of the throat, less so than those of the upper part. A division of the carotid artery is almost necessarily fatal, and that of the internal * For a group of cases of injury to the cervical portion of the spinal cord- consult 'lancet,' July 19, 1856, p. 85. See also 'On Concussion of the Spine,' a clinical lecture by Mr. Skey, ' Lancet,' Jan. 10, 1857. 280 WOUNDS. jugular vein is attended with great danger from haemorrhage, and from the introduction of air into the circulation as well as from the risk of phlebitis. Wounds of the larynx or trachea are attended with com- paratively little danger, and those of the trachea are less important than those of the larynx. The question, Was the woimd the cause of death ? is easily answered, but the question, Was the wound suicidal or homicidal? is less easy of solution. There is also a question of considerable interest relating to wounds of the throat, namely, What amount of voluntary motion is possible after the receipt of a severe wound ? The questions of suicide or homicide, and of the amount of voluntary motion possible after a severe wound in the throat, were raised in the case of Captain Wright, who shared the captivity of Sir Sidney Smith in France, and his celebrated escape from the Temple, and who had the misfortune to be taken a second time and imprisoned in the same place. He was found dead in his bed with his throat cut, and the razor closed in his right hand. There was an extensive transverse wound on the anterior and superior parts of the throat, above the bone of the windpipe, cutting through the skin, the muscles, the windpipe, the oesophagus, and the blood-vessels, and penetrating to the cervical vertebrae. The circumstances of the case are involved in so much mystery that it is impossible to determine by the evidence collected with great pains by Sir Sidney Smith, whether Wright really committed suicide or not. But it is easy to show that the mere fact of the deceased being found with the razor closed in his hand does not militate very strongly against the supposition of suicide ; for, in the case of the suicide of a military officer, which occurred in September, 1838, the head was found nearly severed from the body, and there was no room to doubt the fact of suicide, yet the razor did not fall from the hand, but was placed upon the dressing-table. In a more recent case, a madman, after in- flicting a severe wound on his throat had time to struggle with the maid-servant before he fell down dead. In October, 1833, a man cut his throat with a razor while walking along Oxford Street. He divided the carotid artery and several of its branches, the jugular vein of one side, and the trachea; yet after inflicting the wound he was seen to hold a handkerchief to his neck, and run forwards. He fell dead on the pavement, about four yards fiom the spot where he wouuded himself. The razor was found firmly grasped in his hand. In the remarkable case of Mary Green, who was murdered in 1832 by John Danks, the confession of the culprit, and the circumstantial evidence coincided to prove that, after a wound which divided the trunk of the carotid artery, and all the principal branches of the ex- terrial carotid, with the jugulars, the female must have risen from the ground, run a distance of twenty-three yards, and climbed over a low gate. Fjom actual trial it appeared that it must have taken at least WOUNDS OP THE LUNGS AND HEART. 281 from fifteea to twenty seconds to run from the spot on which the murder was committei to that on which the body was found.* Wounds of the Chest. — Incised wounds of the parietes of the chest are not attended with any peculiar danger, but severe contused wounds by causing fracture of the bones, and consequent injury of the internal parts, often prove fatal. The fatal result is due either to extensive rupture of the viscera, to haemorrhage, or to inflammation. Severe contusions of the chest may also terminate fatally by the shock which they occasion. This class ot' injuries is of common occurrence in prize- fights, in falls from great heights, and from heavy objects crushing the chest. Peneti-atiug wounds of the chest are dangerous, inasmuch as they can scarcely fail to injure some important organ, occasionmg thereby fatal haemorrhage or severe subsequent inflammation ; but cases are recorded of sword and gun-shot wounds traversing the chest, and yet occasioning no bad symptoms, and terminating favourably ; and the majority of cases of injury to the chest which were under Wise- man's care after the battle of Dunbar seem to have recovered. Wounds of the Lungs. — Haemorrhage is the immediate consequence of this class of injuries. The blood may be discharged by the wound, or by expectoration, or it may accumulate in the cavity of the pleura, causing great ditficulty of breathing. When the large vessels are wounded the haemorrhage is copious and speedily fatal. An injury to the substance of the lung itself is not necessarily fatal, for patients have recovered after removal of a portion of the lung, and, in rare instances, foreign bodies, such as bullets, have remained in the lung for years, and have been inclosed in a cyst. Inflammation is a common consequence of wounds of the lung, especially when a foreign substance has been forced into the wound, as happens in injuries with fire-arms. Cases of wounds of the lungs require careful management, and long-continued rest, as without it injuries which have been re- paired may be reproduced. Emphysema is a familiar effect of this class of wounds. When judiciously treated it does not materially increase the danger. Wounds of the Heart. — Penetrating wounds of the heart are neces- sarily speedily fatal from haemorrhage, unless they pass so obliquely through the parietes that the flap aces like a valve, or a foreign body happen to plug the oriflce. Death may be delayed, in these cases, for some hours, or even days. The rapidity with which death takes place will depend upon the situation of the wound. Thus wounds of the base will pi'ove more speedily fatal than those of the apex, and superficial wounds dividing the vessels of the heart less promptly than those which penetrate its cavities. John Bell gives the case of a soldier, in whom the apex of the heart was cut with the point of a very long and slender sword, and this soldier lived twelve hours, during which time, as appeared after his death, the heart had, at every stroke, * See the case more at length in Dr. Taylor's ' Elements of Medical Juris- prudence/ p. 442, 282 WOUNDS. been losing a small quantity of blood, till, in twelve hours, it entirely filled the chest, and the patient was suffocated and died. Another man was wounded with a sword, the point of which cut the coronary artery, which threw out its blood so slowly, that it was two hours before the pericardium filled with blood, and then, after gi-eat anxiety, the patient died.* In very rare instances, when the wound does not prove fatal by hemorrhage, complete recovery has taken place. A case, for instance, is related by Fournier, and authenticated by M. Mansen, chief surgeon to the hospital at Orleans, of a patient, who not only survived a wound of the heart, but may be said to have made a perfect recovery from it, inasmuch as he died at the distance of six years after the receipt of the injury, from disease unconnected with it, and the ball was found embedded in the heart. MM. Ollivier and Sanson have collected a number of cases of penetrating wounds of the heart, with a view of determining the probable period at which these injuries prove fatal. Out of twenty-nine cases of wounds of the cavities of the heart only two proved fatal within forty-eight hours. In the remaining cases, death took place in periods varying from four to twenty-eight days.f Wounds of the Aorta ayid Pulmonary Artery are necessarily fatal ; but patients have been known to live a few days after small punctured wounds even of the aorta. Wounds of the (Esophagus and Thoracic Duct. — Such injuries are necessarily rare from the great depth at which these parts lie. They would be dangerous from the extravasation of their contents. Orfila, however, mentions a case of recovery from a bayonet-wound of the oesophagus. Wounds of the Diaphragm. — Punctured wounds of the diaphragm itself do not appear to be attended with great danger, but they are rarely uncombined with injury to the parts above or below. Hernia of the stomach has sometimes followed these injuries, and proved fatal. Kupture of the diaphragm from severe blows or falls is not an un- common occurrence. In the majority of cases the rupture is attended by a fatal shock to the nervous system, and death is immediate. In other instances it takes place after a longer interval, from the protrusion of the viscera of the abdomen into the chest, and the consequent disturbance of the functions of the organs contained in one or both of those cavities. Wounds of the Abdomen. — Wounds of the panetes' of the abdomen may be attended with serious consequences. Death may take place in incised wounds from a division of the epigastric artery. As in the scalp, so here, there is additional danger from wounds of the tendons of the muscles, and the consequent accumulation of matter beneath them. Ventral hernia is a remote consequence of wounds of the parietes of the abdomen. Contusions of the abdomen are generally attended with * ' Principles of Surgery,' vol. i. p. 468. t ' Diet, des Sciences M^dicales," art. Cos rarex. WOUNDS OF THE VISCERA. 283 serious consequences. Sudden death from shock, haemorrhage from rupture of the viscera, and inflammation, are the chief causes of death. The liver and spleen are the organs most liable to suffer injury, and rupture of their substance is not uncommon. Wounds of the Liver. — Penetrating wounds of this organ, when they extend to any depth, are apt to prove fatal by dividing some of the large vessels. In other cases the danger arises from inflammation of the organ. Wounds of the gall-bladder prove fatal by causing effusion of bile, and consequent peritonaBal inflammation. Wounds of the Spleen. — Deep wounds are fatal by haemorrhage ; but recovery may take place from superficial wounds. Rupture of the spleen from blows on the belly are not uncommon. They prove fatal, according to the amount of injury in from a few hours to several days. In a convalescent patient, a kick over an enlarged and extremely soft spleen caused the effusion of several ounces of blood, and death in a few minutes. (Dr. Robert Williams, ' Elements of Medicine,' vol. ii. p. 470.) Wounds of the Stomach. — These prove fatal by the shock to the nervous system, by ha;morrhage, if the large vessels are divided, by the extravasation of the contents and consequent peritonaeal inflammation, and by inflammation of the viscus itself. Wounds of the stomach, however, are not necessarily fatal, and many cases of recovery are recorded, even when the wound was extensive, and the stomach dis- tended with food at the time of the injury. Wounds of the Intestines. — These injuries may prove fatal in the same way as those of the stomach, viz., by haemorrhage, by effusion of their contents, and consequent peritonaeal inflammation, or by inflammation of the part itself. The danger is greater in the small than in the large intestines, in consequence of tlie more fluid state of their contents, and the greater risk of extravasation. For the same reason, wounds of the duodenum are more dangerous than those of the other small intestines. In the absence of extravasation, there is a fair chance of recoveiy from wounds of the intestines by the effusion and organization of coagulable lymph about the edges of the incision. Wounds of the Kidneys. — The kidneys are chiefly exposed to injury from blows and stabs in the loins. Penetrating wounds of these organs may prove fatal, in consequence of haemorrhage, ex- travasation of urine, or inflammation. If means are taken to pre- vent the urine from being effused into the peritonaeal cavity, recovery may take place. Wounds of the Bladder are chiefly dangerous from extravasation of urine, which is, of couise, most apt to occur when the organ is distended. In the absence of effusion they may prove fatal by the inflammation to which they lead. Rupture of the bladder, though ultimately fatal, does not destroy life rapidly; and the accident 'does not immediately prevent the patient from walking about. 284 WOUNDS. Wounds of the Genital Organs. — A removal of the penis, if not fatal by haemorrhage, is not dangei'ous ; but an incised wound of the urethra entails the risk of extravasation of urine into the cellular membrane and fatal sloughing. The removal of the testicles is attended with less danger than a contusion. This latter injury sometimes proves fatal by the shock to the nervous system. Wounds of the spermatic cord occasion dangerous haemorrhage. The complete removal of all the parts of generation of the male has in many instances led to no bad result. Deep wounds of the labia of the female are dangerous from haemorrhage. Fatal injuries have been indicted on the uterus, bladder, or rectum, or on the large vessels of the pelvis, by instruments intro- duced into the vagina. Consult Mr. Watson's * Medico-legal Treatise on Homicide.' 285 CHAPTER IV. DEATH BY FIRE — SPONTANEOUS COMBUSTION — DEATH BY LIGHTNING — BY COLD — BY STARVATION. DEATH BY FIRE. On the average of the five years 1852-56, no less than 2,623 deaths in Englfind and Wales were attributed to the agency of heat. Of this number 483 were burns, of which 436 by clothes catching fire, 15 by conflagrations, 24 by gunpowder and fireworks, and 7 by explosive gases. 1,548 deaths from the same causes were less accurately de- fined, 46 deaths were caused by drinking hot water; and 541 death by scalding liquids. In the whole five years 2 suicides, 1 murder, and 4 manslaughters were attributed to burning, and 2 manslaughters to scalds. The medico-legal questions that arise in reference to death by fire are similar to those relating to other forms of external injury, except that the alternatives of suicide and homicide very rarely present themselves. The great majority of deaths by fire are accidental. In accidental cases, and in the few cases of suicide and murder, the burning would leave marks on the body showing that it was inflicted during life ; but as it is known that the burning of the body after death is sometimes resorted to by a murderer to conceal the real cause and mode of death, it may be of the utmost importance to distinguish burns inflicted during life from burns inflicted after death. Another medico-legal question may arise when a body is found with marks of injury by burning too extensive to be readily accounted for by the quantity of fuel consumed. It may become a question whether the body so injured was unusually combustible, or whether it might not even be the subject of " spontaneous combustion," This second question will be separately examined. The first question will be now considered. Distinction between burns inflicted during life and after death. — We owe the earliest experiments on this subject to Dr. Christison. But the results which he arrived at have been somewhat modified by sub- sequent experimental inquiries in France and Germany, but especially by those of Champouillon and Chambert. The last-named author seems to have exhausted the subject both by the number and accuracy of his experiments, and we shall therefore adopt the conclusions at 286 DEATH BY FIRE. which he has arrived, with some modifications suggested by the more (^rtain of the results of the earlier writeis. Bums inflicted during life by bodies not so highly heated as to char and destroy the tissues, produce two characteristic appearances — redness and vesication. The redness, more or less intense -according to the temperature and the length of its application, affects the surface and entire substance of the true skin, which is dotted by the deep led openings of the sudoriferous and sebaceous ducts ; and it also extends to the subcutaneous tissues. Blisters, more or less numeious and extensive, also make their appearance under a temperature below that of boiling water, and contain serum, which either coagulates in mass, or yields an enormous piecipitate of albumen when heated, or treated with nitric acid. The albumen is more abundant when wholly due to vital action than when the burn, being inflicted at the point of death, the vesicle forms after life is extinct. These appearances belong equally to burns made at the point of death and to those made twenty hours previously, but vesicles, though generally present, are sometimes absent in burns whatever the period at which they were inflicted. On the other hand, in burns inflicted after death, the surface and substance of the true skin are of a dull white colour, dotted with grey at the openings of the sudoriferous and sebaceous ducts, and the sub- cutaneous tissues are uninjected. No vesicles aie produced by a tem- perature below the boiling point ; and those occasioned by a higher temperature either contain no fluid, or one which, as it contains little albumen, merely becomes opaline or milky when treated by heat or nitric acid. Po.st-mortem vesicles are most readily produced in ana- sarcous suVvjects. The appearances just described as caused by burns inflicted during life, show themselves in all health^ subjects, and probably iu the large majority of sick persons ; but the case of a consumptive patient re- ported by M. Bouchut, shows that the application of heat to the skin of a dying man may produce as little effect upon it as upon a corpse.* It should be understood that the appearances just described as due to the application of heat to the living body are common to all the more intense inflammations of the skin, however produced ; to the application of cantharides and other strong stimulants, to pressure and friction, and even to idiopathic inflammations of the skin. I have seen, on the ankles of a young man who had died of acute phthisis, two patches of inflammation of a deep led colour not removable by pressure, and with well-defined margins, on one of which were large vesicles containing serum. In this case, I ascertained beyond doubt that the spots, which had been observed during life, were not caused by the application of any heated body. In all these cases of acute cutaneous inflammation, a thin vertical section of the inflamed skin and underlying tissues displays, even to the naked eye, distinct red patches, contrasting very * This case is quoted by Chambert in an elaborate paper in the ' Annales d' Hygiene,' April, 1859, to which the reader is referred. SPONTANEOUS COMBUSTION. 287 strikingly with similar sections of skin discoloured by the mere sub- sidence of the blood. It is scarcely necessary to add that redness follows instantly on the application of heat, and that vesicles show themselves after the interval of a few seconds. SPONTANEOUS COMBUSTION. The following case, which rests on the authority of Le Cat, a firm believer in the doctrine of spontaneous combustion, forms a fitting in- troduction to this subject. It is said to have taken place in 1725. A man of the name of Millet, living at Rheims, was charged with the murder of his wife. It appears that the body of the deceased was found lying in the kitchen of the house at a short distance from the hearth, entirely consumed. A part of the head only, with a portion of the lower extremities, and a few of the vertebrae, had escaped combustion. The floor beneath the body was partially burnt. The prisoner, in his defence, stated that he and his wife had retired to rest the pievious evening, — that his wife, not being able to sleep, got up and went into the kitchen, as he supposed to warm herself. He was awakened by the smell of fire, and going down into the kitchen, discovered the deceased lying near the hearth, in the manner stated. The prisoner was condemned to death for the murder, but, on appeal to a higher court, the sentence was revoked, and it was pro- nounced to have been a case of spontaneous human combustion. In this case the extent to which the body was consumed might lend some support to the opinion, that it was more combustible than human bodies in general, but it gives no countenance to the notion that the fire originated in the body itself. It was certainly in the most favour- able cii'cumstances for being set on fire ; and this is true of most of the reported cases of alleged spontaneous combustion which have occurred both in this country and abroad. Orfila testifies his belief in spontaneous human combustion by thus describing the phenomena which accompany it: — A light blue flame appears over the part which is about to be attacked : this flame is not readily extinguished by water, and indeed frequently the addition of this liquid only serves to increase its activity. Deep eschars now form in the part affected, accompanied by convulsions, delirium, vomit- ing, and diarrhoea, followed by a peculiar state of putrefaction, and death. The process is said to advance with extreme rapidity, but the body is never entirely consumed : some parts are only half burnt, while others are completely incinerated, a carbonaceous, fetid, unctuous ash remaining. The hands and feet commonly escape destruction, while the trunk is usually entirely dissipated. The wooden and other combustible ai-ticles of furniture situated near the individual are either uninjured, or but imperfectly consumed ; the clothes, however, cover- ing the body are commonly destroyed. The walls and furniture of 288 DEATH BY LIGHTKING. the apartment are covered with a thick greasy soot, and the air is itn- pregnated with an offensive empyreumatic odour. This phenomenon is stated to have been chiefly observed in corpulent females, advanced in life, and especially in those subjects who had been long addicted to the abuse of spirituous liquors. It is, perhaps, practically of little consequence whether the doctrine of spontaneous combustion be true or false. The cases on i-ecord may be fairly allowed to prove an unusual degree of combustibility of the human tody, occurring in rare instances and, for the most part, in corpulent spirit-drinking females, merely requiring to be set on fire, and needing no other fuel but their clothes, night-dress, or ordinary bed-furniture. Till we possess cases better authenticated, and more accurately reported, we must content ourselves with this amount of knowledge. The spontaneous combustion of inorganic substances is a subject of much interest and importance, but it has no medico-legal bearing. DEATH BY LIGHTNING. From the Reports of the Registrar-General for the five years 1852- 56, it appears that about 21 deaths by lightning occur, one year with another, in England and Wales; 18 in males and 3 in females. This mode of death rarely gives rise to questions of a medico-legal nature ; but inasmuch as the effects sometimes produced on the body, both externally and internally, resemble those inflicted by mechanical vio- lence, a question might possibly arise, whether a person found dead, under unknown circumstances, had perished from the effects of lightning, or had been murdered. In the majority of cases we shall have a clue to the cause of death, by knowing that a thunder-storm has taken place near the spot on which a body is found. This fact being ascertained, we shall next have to inquire what probability there was of the body having been struck by lightning. As a general rule it may be stated, that the electric fluid prefers and seeks out good conductors ; and as the human body is a very good con- ductor of electricity, it is as likely to be struck as any object similarly situated, unless, perhaps, that object be of metal. As a general rule, too, lofty objects are more likely to be struck than low ones ; but this rule is subject to many exceptions, for persons have been struck in the immediate neighbourhood of lofty trees which have been uninjured. The electric fluid is often conducted to the human body by lofty objects in its proximity, such as trees, masts and rigging of ships, and the moist strings of kites. The danger of remaining under a tree during a storm is proverbial. It has been thought that a person is tolerably safe m an open space far from any object which could attract the electric fluid ; but this is CAUSE OF DEATH. 289 an error. The human body may be, in these circumstances, the most prominent object, and, at the same time, the best conductor. It is now understood that death may be caused by an electric shock, other than the lightning stroke. This takes place when a cloud, in near proximity to the eartli, is negatively electrified, whilst the earth is positive. The human body is heie made the conductor, by means of which the equilibrium is restored. This is called the ascending or returning stroke. The violent effects produced by the electric discharge — the disruption of the several parts of a building, and their forcible removal to a dis- tance ; the separation of the good conductors from the bad ones; the fusion of metallic substances ; the ignition of inflammable ones ; the magnetic properties communicated to articles of iron and steel — are familiarly known. The Post-mortem appearances in the bodies of those who have been struck by lightning are very various. Sometimes no marks of vio- lence are found on the body, and this is said to occur most commonly in cases of death produced by the returning stroke. At other times the body presents marks of violence, such as contusion and laceration about the spot where the electric fluid has entered ; occasionally there is merely a small round hole at the point of exit ; at other times there is an extensive ecchymosis, and this is most commonly found on the back, the electric fluid appearing to prefer the track of the spinal marrow. Fracture of the bones is a rare occurrence. They may occur, as Ambrose Pare states, without external wound. One case of extensive fracture of the bones of the skull is related by Pouillet. Marks of burns are not fiequently met with, and probably never, except in cases where the clothes have been set on fire. The state of the blood, alleged by some authorities to be fluid, by others to be coagulated ; the state of the limbs, asserted by some authors not to grow rigid, but by other authors, with better reason, to be sub- ject to rigidity, and sometimes even to become quickly and excessively rigid ; and the putrefactive process, stated by Pare and others to be retarded, but by other authorities to be hastened, — are trivial signs, of little medico-legal importance. The state of the body in these respects is worthy of note ; but even should it be clearly made out that the blood is fluid, rigidity absent, and putrefaction hastened, these circum- stances could not be considered peculiar to death by lightning, for there is reason to believe that all of them may coincide in other modes of sudden death. In some cases the state of the objects found upon the person furnish very complete evidence of the cause of death. The clothes may be torn and burnt ; metallic bodies fused and forcibly carried to a distance from the body ; and articles of iron or steel, such as the steel of the stays, or the main-spring of a watch, rendered strongly magnetic. Cause of Death. — The power of the electric fluid shows itself chiefly through the nervous system. If death takes place, it is through the U 290 DEATH FROM COLD. shock sustained by it; or if a less degree of injury is inflicted, it is manifested on the brain, spinal marrow, or nerves, in loss of sight, sen- sation, or voluntary motion, temporax-y or permanent. DEATH FItOM COLD. Death from cold is an uncommon event in this country, though death by cold and inanition combined is not of very rare occurrence in severe winters. The first effect of intense cold is a sensation of numbness and stiff- ness in the muscles of the limbs and face. This is soon followed by torpor and profound sleep, passing into coma and death. The effects of cold are manifested partly on the general circulating system, and partly on the circulation through the brain. The effect on the circulating system generally is to drive the blood fi-om the surface to the interior of the body, so as to gorge the spleen, liver, lungs, and brain with blood. The genital oigans are similarly affected, priapism sometimes resulting from congestion of the vessels of the penis. The temperature of the blood itself is lowered ; the heart contracts slowly and feebly, and the pulse becomes small and thready. The congestion of the nervous centres occasions numbness, torpor, somnolency, giddiness, dimness of sight, tetanus, and paralysis ; and the congestion of the brain sometimes occasions a species of delirium as happened to Edward Jenner, or the appearance of intoxication, as wit- nessed by Captain Parry and others in the expeditions to the North Pole. The effect of cold varies in intensity in different persons according to their sex, age, and strength: the young, the aged, the infirm, persons worn out by disease or fatigue, and those addicted to the use of intoxi- cating liquors perish most promptly. It would appear, too, that, independent of these circumstances, some persons have a great advan- tage over others in their power of resisting cold — a fact frequently observed by voyagers and travellers in the Arctic regions. The circumstances which cause the impression of cold on the body to be severely felt, and which give rise to effects not indicated by the height at which the thermometer stands will be understood from the following considerations : — The body is cooled in three ways — by cutaneous exhalation ; by conduction from the direct contact of air ; and by radiation. The cutaneous exhalation is increased by dry and diminished by moist air. The body, therefore, parts with its heat more rapidly in a dry atmosphere. On the other hand the body is cooled by conduction, when the air is moist ; so that the body is cooled alike by dry cold air and by cold moist air. Cold humid winds lower the temperature of the body in a very striking degree. DEATH FEOM STARVATION. 291 A rapid renewal of the air, as in a brisk cold wind, lowers the temperature of the body by evaporation and by conduction at the same time. The effect of a slight breeze in increasing the feeling of cold was remarkably exhibited m the expeditions to the polar seas. Post-mortem Appearances. — The surface of the body is pallid, and the viscera of the head, chest, and abdomen are congested. There is congestion of the vessels of the brain, but extravasation does not appear to have been noticed, though the old opinion of the cause of death was in favour of apoplexy. In two cases reported by Dr. Kellie, of Leith, there was a large effusion of serum in the ventricles of the brain. The blood in the aorta and left cavities of the heart is stated by Dr. Paris, on the authority of Sir B. Brodie, to be florid. It will be seen that none of these appearances are so characteristic as to be in tliemselves conclusive as to the cause of death. DEATH PROM STARVATION. This is an extremely rare event ; but death from cold in persons in- sufficiently nourished is not infrequent. Cases of homicide by the deprivation of food, are of occasional occurrence, and insane persons, and those who seek to avoid some greater calamity, such as capital punishment, sometimes commit suicide by obstinately refusing to take sustenance. The Symptoms produced by protracted Abstinence are pain in the epigastrium, relieved by pressure ; emaciation, the eyes and cheeks sunken, the bones projecting, the face pale and ghastly, the eyes wild and glistening, the breath hot, the mouth dry and parched, intolerable thirst, delirium, extreme prostration of strength. After a longer interval the body exhales a fetid odour, the mucous membranes of the outlets become red and inflamed, and death takes place in a fit of maniacal delirium, or in horrible convulsions. The period required to produce fatal effects varies with the age, sex, and strength, and with the amount of exertion ; and it also depends in a great degree on the command of liquids, for the experiments of Redi have shown, that animals live more than twice as long when they have access to water as when they are kept without it. Cases are on record in which life has been prolonged tinder volun- tary starvation for a considerable period ; in one case (that of Viterbi), twenty-one days, and in a still more remarkable one, fifty-eight days. This, which occurred in the south of 'France, and was reported to the Academy of Medicine, is as follows : — GuillauEie Granet was a prisoner at Toulouse, and he resorted to starvation to avoid punishment. For the first seven days the symp- toms were not very remarkable ; his face was flushed, his b)eath foul, and his pulse small and feeble. After this period he was compelled to drink water occasionally, to relieve the excessive thirst which he suffered, but in spite of the close watch which was kept over him, he 292 DEATH FROM STARVATION. frequently drank his urine, or the water of the prison-kennel. His strength did not appear to fail him during the greater ])art of the time, and, with varying symptoms of constitutional distuibance and acute sufferings, he lingered till the fifty-eighth day, when he expired, after struggling for four hours in convulsions.* Post-mortem Appearances. — The body is much emaciated, and exhalea a fetid odour ; the eyes are red and open, the skin, mouth, and fauces dry, the stomach and intestines empty and contracted ; the gall- bladder is distended with bile ; the heart, lungs, and large vessels collapsed, and destitute of blood ; and putrefaction runs a rapid course. These appearances are not so characteristic as to be decisive of the mode of death; but in the absence of any disease productive of ex- treme emaciation, such a state of body will furnish a strong presump- tion of death by starvation. It must be recollected, that there are maladies such as stricture of the oesophagus, and organic disease of the stomach, which prove fatal by starvation. Search should, therefore, be m.ade for such causes of death. The time that a person may reraain without food, or may support life on a very scanty supply of it, may become a question of some im- portance, as will appear Irom the case of Elizabeth Canning, quoted by Dr. Cummin in his Lectures in the * Medical Gazette,' vol. xix. The question raised in this case was, whether a girl of eighteen could be confined, in the depth of winter, twenty-eight days, without fire, with about a gallon of water in a pitcher, and with no food but some pieces of bread, amounting altogether to about a quartern loaf, and a small minced pie which she happened to have in her pocket, and at the expi- ration of the period retain sufficient strength to break down a window- shutter fastened with nails, get out of the window on to a sort of pent-house, thence jump to the ground, nine or ten feet below ; and finish by walking from Enfield Wash to Aldermanbury. To this question we should be strongly inclined to return an answer in the negative. The cases which have been alluded to, and especially that of Guillaume Granet, give us good ground for believing, tiiat life might have been prolonged for twenty-eight days, or even more, on this scanty sup|)ly of nourishment ; but it is extremely improbable that, at the end of this time, she would have had strength enough left to effect her escape. This case is also curious in its bearing on the question of identity. The longest abstinence from food, with free access to water, of which J have experience among prisoners is ten days. In two men and one woman complete abstinence from food during this period was followed by no bad symptom, and the ordinary prison diet was resunCM without injury to health. The prisoners were weakened, but by no means exhausted. * Fodere', vol. ii. p. 276, 293 PAET III. TOXICOLOGY. The frequent occurrence of cases of real or supposed poisoning, and the complicated nature of the questions to which they give rise, render this the most important division of Forensic Medicine ; while the great number of recognized poisonous agents causes it to occupy no incon- siderable part of every medico-legal treatise. The first suspicion of poisoning usually assumes a somewhat inde- finite shape, and the question raised is not so much what poison has been taken as whether any poison has been taken. In seeking a solution of this question it is natural first to consider, to the operation of what class of poisons the symptoms which have suggested the suspicion bear the nearest I'esemblance ; and then to select from the members of that class the individual poison of which the effects cor- respond most closely with the symptoms in question. This, which is the natural order of inquiry, is also the most convenient one. Accord- ingly a distinct chapter will be devoted to the subject of Poisons in General ; including the definition of the term poison, the mode of action of poisons, the causes which modify their action, the evidence of poisoning, and the classification of poisons. This chapter will be followed by a series of chapters in which the individual poisons will be grouped according to their analogies, and separately examined. CHAPTER I. ON POISONS IN GENERAL. DEFINITION OF A POISON. The first question of a general nature which offers itself for solution relates to the meaning of the word Poison. The term poison does not admit of strict definition ; but the meaning which ought to attach to it may be ascertained by a simple process of exclusion. A substance which affects one person in consequence of 294 ON POISONS IN GENERAL. some peculiarity of constitution, but has no effect upon other persons, is not a poison : a substance which proves fatal in consequence of some temporary condition of system, as cold water swallowed by a person heated by exercise, is not a poison : substances which prove fatal through the mechanical irritation they set up in the internal parts, such as pins and needles, and particles of steel or glass, are not poisons: again, hot water may prove fatal when swallowed, but water being harmless in itself, and injurious only as a vehicle for conveying heat, is not a poison. Substances, therefore, which owe their fatal effects to some peculiarity of constitution, or to some unusual condition of the body ; as well as mechanical irritants, and substances naturally harm- less, but rendered injurious by extraneous causes, are not to be consi- dered as poisons. The mode in which a substance is applied to the body forms also no part of the definition of the term poison. It may be applied to the skin, or inhaled, or swallowed, or introduced into the anus or vagina, or into the ear, but it is still a poison. Again, the quantity of a given substance which may prove fatal, or the time during which it may continue to act before death takes place, cannot be allowed to enter into the definition ; for in both these respects un- doubted poisons differ widely from each other. These exclusions have narrowed the possible definition of a poison ; and although from the nature of things precision is impossible, the following may be adopted as the nearest approach to a definition : — A poison is any substance which, when applied to the body externally, or in any way introduced into the system, without acting mechanically, but by its own inherent qualities, is capable of destroying life. In by far the greater number of medico-legal cases poisons are swal- lowed. Hence the definition of a poison has been sometimes so framed as to exclude all other modes of application ; and the words " admi- nister," or '* cause to be taken by," which are used in the statute 1 Vict., cap. 85, would seem to imply this mode of introducing a poison into the system. The word poison is frequently qualified, in common conversation, by such tei-ms as " active" " virulent," " deadly," and the last of these terms is very generally used in indictments. A " deadly poison " may mean a substance which proves fatal in a small dose, or one which in a larger dose destroys life very rapidly, or one which, irrespective of the dose, is more likely to prove fatal, or more difficult to counteract, than others. Strychnia and oxalic acid, for instance, are both " deadly poisons ;" but while less than a grain of the one may destroy life, about half an ounce of the other is re- quired for the same purpose ; yet a full dose of oxalic acid may prove much more rapidly fatal than even a large dose of strychnia. On the other hand, Epsom salts or sulphate of potash, in order that they may destroy life, must be given in considerable quantity, and, even when so given, do not prove certainly or rapidly fatal : so that it would obviously be iucoiTect to designate these substances as ** deadly MODE OF ACTION OF POISONS. 295 poisons." Nor would the term be correctly applied to such a sub- stance as sulphate of zinc, which is often prescribed as an emetic in doses of a scruple or half a drachm, or to the non-corrosive prepara- tions of mercury, iron, or copper. In any case the term " deadly poison" is open to the objection of raising an unnecessary vei'bal question, and unless it is to be looked upon, when used in indictments, as mere " legal surplusage," in accordance with the opinion lately expressed by Mr. Justice Earle, it ought to be allowed to fall into disuse. " A destructive thing," is another phrase used in the statute just referred to, and open to question. A destructive thing, if not a poison, in the sense ordinarily attached to that term, must be some substance which destroys life by a mechanical action on the internal parts, or by some property not inherent in it, such as heat. Some substances, as sponge, or plaster of Paris, may destroy life by presenting an obstacle to the passage of the contents of the intestines ; others, as large particles of glass or steel, by irritating the Iming membrane of the alimentary canal ; and pins or needles, by wounding vital organs, or by setting up inflammation in the less important parts which they traverse. Such substances may be fairly regarded as " destructive things :" but whether they have caused death in any particular instance can be determined only by a post-mortem examination. Having defined the term poison with sufficient precision to indicate the class of substances which will have to be examined in the follow- ing pages, certain general questions relating to poisons must next be considered. These are, — Their mode of action, and The causes which modify their action. MODE OF ACTION OF POISONS. The action of poisons is twofold, local and remote. The local action of poisons may consist in con^osion, or chemical de- composition, as when a concentrated mineral or vegetable acid, a pure alkali, or a corrosive salt, is applied externally or taken internally : in irritation or inflammation, in various- degrees, and followed by the several terminations of adhesion, suppuration, ulceration, or gangrene, as from the application of arsenic, tartar-emetic, or cantharides : and, lastly, in an effect on the nerves of -sensation or motion ; as the numb- ness and tingling of the lips and tongue, occasioned by chewing the leaves, seeds, or root of monkshood, and the sharp pricking sensation in the same parts, caused by the arum maculatum ; the loss of sensation in the skin by the application of the vapour of prussic acid ; and the dilatation of the pupil from the application of belladonna, to the eye. The remote action of poisons is of two kinds, common and specific : the first resembling the effect of othe)' forms of severe injury inflicted on the same part, and varying in intensity with the amount of that injury ; the last being peculiar to the poison itself. Thus, arsenic 296 ON POISONS IN GENERAL. when swallowed, and applied to the raucous membrane of the ali- mentai7 canal, gives rise to those severe cramps in the extremities which are present in all acute inflammations of the lining membrane of the stomach and bowels, however produced ; but the same poison, inserted into a wound, applied to the skin, or inhaled by the lungs, excites inflammation of the mucous surfaces with which it does not come into immediate contact. This is its specific action. Again, oxalic acid acts on the mucous membrane of the stomach and bowels as a corrosive, and excites inflammation around the parts of the membrane which it has destroyed ; and this destruction and consequent inflamma- tion are attended with the same constitutional shock that accompanies all severe local injuries; but it has also a remote specific effect on the brain and spinal coi-d, and on the heart. The purest example of a remote constitutional effect of a common kind is afforded by the mineral acids, and by the pure alkalis and their carbonates, which, by the local destruction they occasion, give rise to the common symptoms of collapse — extreme debility, faintings, imperceptible pulse, cold ex- tremities, and death. The absence of remote specific effects in the case of these chemicals has led some authors to doubt the propriety of classing them among the poisons. The remote specific effects of poisons may also be distinguished as constitutional or local ; that is to say, as producing a general effect on the whole frame, or a partial effect on a particular organ. Tartar- emetic, for instance, has a peculiar depressing effect upon the system, and a peculiar local action on the lungs ; while arsenic acts as a stimu- lant to the system, and exerts a local action on the mucous surfaces. A knowledge of the specific remote action of poisons is of the first importance, as it often enables us to judge of the particular poison which has been taken, or of the class of poisons to which it belongs. Thus the narcotic poisons, as a class, occasion stupor, the narcotico- acrids, delirium. Nux vomica, and the several plants of which strychnia is the active principle, affect the spinal cord, producing violent attacks of tetanus ; conia, the active principle of hemlock, [paralyses the whole muscular system ; arsenic, even when applied externally, causes in- flammation of the mucous membrane of the alimentary canal ; mer- cury attacks the salivary glands and mouth ; cantharides the urinary system ; antimony the lungs ; manganese the liver (and this is an effect of copper) ; chromate of potash the conjunctiva of the eyes ; iodine the lymphatic glands ; lead the muscular system generally (and this, too, is an occasional effect of arsenic) ; and spurred rye produces gangrene of the limbs. Poisonous substances used in the arts also reveal their effects upon the system through their specific actions. Thus the dropped hand betrays the use of lead, paralysis agitans that of mercury, gangrene of the jaws that of phosphorus, and a peculiar rash, with the formation of small ulcers about the nostrils, ears, bends of the arms, and scrotum, the employment of the arsenite of copper. In the case of some of these poisons, one part or set of organs only is MODE OF ACTION OF POISONS. 297 affected, but others attack almost every impoi-tant organ of the economy. The most striking; example of this kind is arsenic, which, besides pro- ducing inflammation in the parts with which it comes in contact, affects all the mucous surfaces, as well as the organs of circulation, respiration, and innervation ; and all these effects may be exhibited in the same case. Oxalic acid and the salts of mercury produce similar complications. in producing these remote specific efiects, poisons must either be carried by the circulation to the parts affected, or their action on the nerves of the part to which they are applied, must be propagated to the nervous centres, and thence reflected to the organs remotely affected. Now there is abundant proof of the absorption of poisons, and their consequent circulation through the system. Experiments on animals have shown that this takes place in whatever manner the poison is applied to the body ; and the results of such experiments have been confirmed by the analysis of the blood and secretions, and even of the solid textures; the list of the poisons thus detected including almost every substance which can be recognized by its odour or colour, or which, not being decomposed by the animal fluids or textures, can be submitted to chemical reagents. Hence the bare fact of the ab- sorption of poisons is too generally known and admitted to require additional proof or illustration; but the questions arise — Is it in con- sequence of absorption that- poisons prove fatal ? Is their action arrested or postponed by the arrest of the ciiculation ? As the greater number of experiments which have been made in illustration of these questions have consisted in the introduction of poisons into wounds, it may be well to consider by themselves the arguments derived from this mode of introduction. In the first place, it has been satisfactorily shown, that poisons so introduced do not act directly on the nerves of sensation or volition, for their action is not impaired by the previous division of the nerves supplying the part into which the poison is introduced, and they continue to take eflect even when, as in Majendie's well-known experiment, the poisoned limb is con- nected with the body only by quills introduced into its large vessels. It is also clear that the great nervous trunks are not abJe to transmit the poisonous influence, for poisons inserted into a limb do not produce their effect when the limb is connected with the body by nerves only. Again, a division of the. spinal marrow does not prevent the action of those poisons which prove fatal by attacking that part, and the direct contact of poisons with the substance of the brain itself has been found to be unattended with their usual effect. This class of experiments, therefore, affords a very strong presumption in favour of the necessity of absorption to the action of poisons. But the introduction of poisons into wounds is only one way in which they may gain admission into the body. It is necessaiy to inquire how poisons which have been swallowed produce their effects. Is absorption necessary to their fatal action? An experiment per- formed by Mr. Blake proves this necessity as strongly as in the case ay» ON POISONS IN GENERAL. of poison inserted into wounds. Prussic acid was introduced into the stomach through an opening in its parietes ; it produced no effect, so long as the vessels entering the liver were secured by a ligature, but began to act within one minute after its removal.* It appears, then, that poisons, whether inserted into wounds or in- troduced into the stomach, produce their fatal effects in consequence of absorption, and that, where absorption is altogether f)revented, these effects do not occur. The question now arises — In what manner do poisons, introduced into the blood and circulated through the system, produce their fatal effects? On what part and on what tissue do they act ? It is plain that all poisons do not destroy life in the same way. Some paralyse the heart, others act directly upon the lungs, and give rise to asphyxia; a third class attack the brain; a fourth tlie spinal marrow ; and a fifth class appear to affect the entire capillary circula- tion. This difference of action is displa)ed in a marked manner when poisons are introduced, as in the ex})eriments of Mr. Blake, directly into the current of the circulation. So introduced, the salts of magnesia, lime, strontia, and baryta; of zinc, copper, lead, and silver; as well as oxalic acid and digitalis, affect the heart ; the salts of soda, hydro- cyanic acid, tobacco, and euphorbium attack the capillaries of the lungs ; opium and its alkaloid, morphia, affect the brain ; while the action of the salts of potash and ammonia seems to be limited to the general capillary circulation,! These different modes of death can only be accounted for in one of two ways, — the poison must be conveyed with the blood to the organ affected, or some powerful influence must be transferred to that organ from the nerves distributed to the coats of the blood-vessels themselves. The latter supposition seems, in the highest degree, improbable; for in a second experiment performed by Mr. Blake, blood poisoned with woorara continued to traverse both the arteries and veins of the abdominal viscera for several minutes before any effect manifested itself. This experiment, taken by itself, affords a sufficient refutation of the theory which the ingenious experi- ments of Morgan and Addison were intended to establish. Considerable and very important additions have been lately made to our knowledge of the action of poisons, and of the proximate cause of death in poison- ing, by M. Claude Bernard. He has shown by well-devised experiments on animals that the more active poisons attack paiticular tissues or organs essential to life — that woorara paralyses the motor nerves; that strychnia attacks the sensitive portion of the nervous system, and excites fatal reflex actions ; that digitalis, upas antiar, coiTowal, and wao, veratrine, and several other poisons, act on the muscular tissue throughout the body, and on the heart as a muscle.;}; * For minute particulars of this and of similar experiments see Mr. Blake's Essay in the ' Edln. Med. and Surg. Journal,' vol lill. p. 45. t ' Ed. Med. and Surg Journal.' vols. 11., llv., and Ivi. % See his lectures in the ' Medical Times and Gazette,' vol. ii. 1860, Nos. 532. 533, 535. MODE OF ACTION OF POISONS. 299 There remains, then, but one explanation of the action of poisons when once. introduced into the blood-vessels, namely, that they aie car- ried with the blood to the organs or tissues on which they act : some by the coronary arteries to the heart, which they paralyse ; others to the spinal marrow, exciting fatal tetanic spasms ; others to the brain, proving fatal by an indirect action on the respiration ; and others, again, to the lungs, causing an arrest of the capillary circulation, and consequent asphyxia. One difficulty which stood in the way of the reception of the theory of the necessity of absorption to the action of poisons, namely, the rapidity with which certain poisons, such as pr^issic acid, prove fatal, has been removed by the ingeniously-contrived and carefuUy-pei'formed experiments of Mr. Blake. Having provided a delicate measure of the condition of the circulating system, by inserting into the femoral ar- tery of the animal to be experimented on, the hsemadynamometer of Poiseuille, he proceeded to ascertain the time required for the circula- tion of poisons from one part of the system to the other. This he effected chiefly by introducing various substances, previously known to paralyse the heart, directly into the vessels, and, by means of the in- strument, noting the instant of time at which the first effects of the poison manifested themselves, and at which the heart ceased to beat. Without entering into a minute account of the experiments themselves, it may suffice to state, that, in the dog, the time required for a poison to pass from the jugular vein to the lungs was four seconds, or from four to six seconds ; from the jugular vein to the coronary arteries of the heart seven seconds ; from the jugular vein to the carotid artery five to seven seconds, and from the aoita to the capillaries, four se- ' conds. A poison introduced into the jugular vein was distributed through the whole body in nine seconds. In the horse, the time re- quired for the completion of the circulation was from twelve to twenty seconds, or somewhat less^ than the time (twenty-five seconds) deduced by Hering of Stuttgardt, from his experiment. These experiments are in harmony with the more recent ones of M. Claude Bei-nard. A saturated solution of sulphuretted hydrogen, introduced into the jugular vein of a dog, began to be eliminated from the lungs in three seconds ; and when injected into the femoral vein of the same dog, in six seconds. Assuming that the time required for the complete circulation of a poison through the body of a dog is nine seconds, it follows that if it can be shown, that poisons applied to the dog's tongue do not act in so short a space of time, absorption may take place, and the blood may be distributed to the organ on which it produces its fatal effects. Now, in Mr. Blake's experiments, strong hydrocyanic acid applied to the tongue of a dog did not begin to act till eleven seconds, and did not prove fatal till thirty-three seconds; and when a tube was previously introduced into the larynx, so as to prevent the vapour of the acid from entering the lungs, the first appearance of the symptoms was after 300 ON POISONS IN GENERAL. sixteen seconds, and death took place in forty-five seconds. In like manner, nicotina, the essential principle of tobacco, applied to the tongue of the same animal, did not prove fatal till twenty seconds. These experiments afford very strong confirmation to the theory of the necessity of absorption to the fktjil action of poisons, and must be admitted to prove that necessity, at least in the great majority of cases. Jf the theory of the fatal action of poisons by an effect produced on the nerves of the part to which they ai'e applied be tenable, it must be in those rare instances in which the fatal action of the poison is reported to have been liteially instantaneous, or much more prompt than in any of Mr. Blake's experii^ents. Such an experiment is reported by Dr. Christison, who states, that in one instance an animal was killed out- right by piussic acid in -four seconds ;* and cases are cited by the same author, and by Dr. Taylor, f in which the same poison destroyed life in three, and even in two, seconds ; and in the experiments of Sir Ben- jamin Brodie, alcohol and the essential oil of bitter almonds seem to have produced the same instantaneous effect.^ In the presence of these facts, and v^ith the knowledge we possess of the instantaneous impi-ession produced upon the system by sudden and extensive mechanical and chemical injuries, it would scarcely )je safe to deny the possibility of the more active poisons when taken in large doses pioving fatal by a sudden shock to the system. A fact i-eported by Sir B. Biodie renders it probable that poisons may act through continuity of tissue. A man was bitten in the hand by a rattlesnake. There was inflammation, sloughing, and suppura- tion of the cellular tissue of the arm, and copious and extensive extra- vasation of blood beneath the integuments of the chest and back, limited to the injured side of the body. The theory of absorption finds a p'-actical application in the use of ligatures and cupping-glasses for preventing the effects of poisons inserted into wounds. CAUSES WHICH MODIFY THE ACTION OF POISONS. There are three ways in which the action of poisons may be modi- fied. 1. By the quantity and form in which they are administered. 2. By the part of the body to which they are applied ; and 3. By the condition of the body itself. 1. Quantity and Form of the Poison. — Quantity. As a general rule, the larger the quantity of a poison introduced into the system the more prompt and the more severe its effects; but in the case of poisons which are swallowed, a large dose will sometimes be immediately and completely discharged by vomiting, while a smaller dose will remain * ' Treatise on Poisons,' p. T. t ' Medical Jurisprudence,' 5th Edition, p. 160. X Sir Benjamin Brodie's ' Pliysiological ilesearches,' p. J 39, CAUSES WHICH MODIFY THE ACTION OF POISONS. 301 on the stomach, and prove fatal. Again, small doses of a poison often repeated, will develop different symptoms from those caused by a single large dose. The operation of some poisons also varies remarkably in kind as well as in degree with the quantity taken. Thus oxalic acid in a large dose may destroy life almost instantly by shock ; in a smaller dose it may affect the heart in a less degree, but still prove fatal by its action on that oi'gan; in a yet smaller dose it affects chiefly the spinal cord ; and in a more minute dose still, the brain. Of the whole class of uarcotico-acrid poisons, it may be affirmed, that when given in large doses they act chiefly as narcotics, and in smaller doses chiefly as irri- tants. Form. — Under this head will have to be considered, — a. The State of Aggregation, b. The Chemical Comhination, and c. The Effect of Mixture. a. The State of Aggregation. — Poisons in solution act more ener- getically than when in a solid form, partly because they are more readily absorbed, and partly because they are brought into contact with a larger surface. For the same reason soluble poisons are much more active than those which are sparingly soluble, and the soluble salts of a poison more active than the less soluble base. Poisons also act when in a state of vapour, with great energy on the lungs and skin. But poisons are not merely rendered more active by solution: their effects are also modified by it. Of this oxalic acid is a remarkable example. 6. Chemical Combination. — As a general rule, substances which have a purely chemical action, as the mineral acids and the alkalis, lose their active properties when in combination. The resulting substance ob- tains new properties, and. is more or less active as it is more or less soluble. Acid poisons, in combining with bases, or basic poisons com- bining with acids, become more or less active as the resulting com- pounds are more or less soluble; and, as a general rule, those compounds retain in their soluble combinations the specific characters of their active ingredient. Thus all the soluble salts of morphia have the same action, and all the soluble compounds of oxalic acid affect the system in the same way. When two poisonous substances combine to form one chemical compound (as arsenious acid with copper, or hydrocyanic acid with mercury or silver), the resulting compound may give rise either to the symptoms of the more active element, or to the mixed effects of the two poisons ; or it may produce symptoms peculiar to itself. Lastly, some poisons insoluble in water, as arsenite of copper, and car- bonate of lead or baryta, may be rendered soluble anil active by the juices of the stomach, or by the acid of the perspiration. c. Mixture. — All admixtures which render a poison more soluble render it more active. All other admixtures have a contrary effect. Thus acids increase the activity of opium, and of the salts of coppei-, and water of arsenic. Mucilaginous substances, on the other hand, partly by protecting the coats of the stomach, and partly by involving the poison, if in substance or in powder, retard or prevent its action. Food taken before or with poison has the same effect. Hence the 302 ON POISONS IN GENERAL. frequent escape of those who have taken very large doses of arsenic or corrosive sublimate. Poison mixed with food is similarly affected by the character of the food. Thus arsenic given in a solid dumpling would manifest its effects much more slowly than if taken in porridge, and in this latter case than if mixed with tea, beer, or water. So also with the more deadly poisons when given in the form of medicine. Thus sti-ychnia given in a pill acts more slowly than the same poison administered in a draught or mixture. We avail ourselves of the pro- tecting effect of admixture with mucilaginous substances in the treat- ment of cases of poisoning, and we use substances possessed of little or no power as antidotes, because they possess the property of withdrawing and holding in suspension certain poisons. Powdered charcoal is the best example of this class ; but magnesia and the sesquioxide of iron given in poisoning by arsenic owe their repute chiefly to this power. 2. The Part to which the Poison is apj^lied. — The effect which the same poison has on different parts of the body is directly as the ab- sorbing power of those parts. Thus poisons act most promptly when injected into a vein ; next in degree when introduced into a wound ; the serous surfaces hold the next place ; then the stomach ; and, last of all, the unbroken skin. Poisons introduced into the lungs, whether in a fluid or a gaseous form, act with nearly as great rapidity as when introduced directly into the circulation. The corrosive poisons and stronger irritants produce an effect proportioned to the importance of the part to which they are applied. Thus, the mineral acids prove speedily fatal if they come into contact with the windpipe ; less speedily by acting on the gullet and stomach, and they are still less active when applied to the skin. It is a remarkable fact, that even those poisons which most strikingly affect the nervous system do not act when applied directly to the brain, spinal marrow, or trunks of the nerves. Many animal poisons, which, as a- class, are readily decomposed, have, as might be anticipated, no effect on the stomach, though the smallest quantity introduced into the skin proves cei-tainly fatal. Thus the poison of the viper or mad dog may be swallowed with impunity. 3. The Condition of the Body itself. — Under this head will have to be considered, — a. Habit, b. Idiosyncrasy, c. Disease. a. Habit. — It is not possible to lay down any bi-oad general rule in reference to the influence of habit on the effect of poisons. For while some poisons derived from the vegetable kingdom, and belonging to the class of narcotic or of narcotico-acrid poisons, as opium, alcohol, and tobacco, lose their effect by repetition, and may be taken at length in doses which would poison a man not accustomed to their use, other poisons belonging to the same classes, as digitalis and strychnia, have a cumulative effect. Again, though the less deadly mineral poisons, such as the common salts of zinc and iron, may be taken by healthy persons in continually increasing doses, the more active poisons, such as arsenic and meicury, seem to share with strychnia and digitalis a cumulative property ; and when gradually introduced into the system IDIOSYNCRASY. — DISEASE. 303 in their use in the arts, they certainly appear, like the carbonate of lead, to be the more dangerous the longer they are used. Nor does habit seem to render men who work with arsenite of copper more tolerant of the poison. The same effects appear to be reproduced at each resumption of their employment. The stomach may, however, become accustomed to the local action of poisons, and grow nearly in- sensible to them, as happens with the spirit-drinker ; and it is perhaps possible that the stomach may become tolerant of increasing doses of arsenic or corrosive sublimate. It must be borne in mind, however, that even those substances to the action of which the system most readily adapts itself, produce permanently injurious effects on the system. Thus, alcohol causes disease of the lungs, liver, kidneys, and brain; tobacco, however frequently repeated, still excites the circula- tion ; and opium injures the digestion, emaciates the body, and enfeebles the mind. h. Idiosyncrasy. — There are three ways in which individuals differ from each other, or from the majority of their fellows. 1. They are affected in a greater or less degree than is usual by a substance which produces the same effect in them as in other men. Thus, a few grains of mercury shall salivate one man, but as many drachms or ounces shall not affect another. The same remark applies to arsenic, A child, too, shall bear a larger quantity of mercury than an adult ; probably because his functions being more active, the substance is sooner removed from the system by the secretions. 2. A substance which, in the majority of persons, produces one given effect, shall in an individual act in a very different manner. Thus, common Epsom salts have been known to act like opium, and opium to have a purga- tive effect. Lastly, a simple article of diet, which has no more efliect on most men than any other food that they take, shall act like a poison on the stomach of a few individuals. Thus, certain kinds of fish and vegetables, and even common butcher's meat, act like irritimt poisons on some persons. Even mutton has been known to act invariably in this way. c. Disease. — The general effect of a state of disease is to render the body less susceptible of the action of poisons. Thus, persons in an advanced stage of typhus fever, or otherwise reduced to extreme weak- ness, are scarcely affected by stimulants which would overpower the strong ; and this is seen even in healthy persons in the increased tolerance of spirits towards the after-part of the day, when the body is comparatively weak. In continued fever and in yellow fever there is increased tolerance of mercury, but in paralytic affections, and in anaemic states of system, an opposite condition prevails : in anaemia, large doses of preparations of steel are readily borne ; in severe dysentery, cholera, and haemorrhage, of opium ; in all the moi-e severe affections of the nervous system, as tetanus, hydrophobia, delirium tremens, and mania, every remedy, but especially the narcotic poisons, may be given in greatly increased doses. Delirium tremens may be safely and sue- 304 ON POISONS IN GENEIIAL. cessfuUy treated by half-ounce doses of tincture of digitalis, and opium may be given in one form of mania in repeated doses of two scruples. The only exception to the general rule here laid down is in the case of poisons which tend to produce conditions of system similar to those actually existing. Thus, the irritants would increase gastritis, diar- rhoea, or dysentery; and the narcotics exasperate a determination of blood to the brain. Besides these three principal modifying causes, there is one condi- tion of system which deserves mention as tending to diminish the operation of poisons, viz. sleep. This is too obvious to require any comment, as in this state all the functions are carried on more slowly, and all effects on the system must of necessity be less severe. On the same principle, substances which produce sleep being administered with or before other poisons, must weaken or counteract their effects ; opium, for example, when given with arsenic not only masks the symptoms proper to that poison, but appears to retard its operation. EVIDENCE OF POISONING. Under this head it is proposed to examine very briefly the chief circumstances which would lead us to believe that an illness or death, accompanied or preceded by suspicious symptoms, was due to poison, using the term poison in a general sense. There are five such cir- cumstances. 1. The symptoms. 2. The post-mortem appearances. 3. The results of experiments on animals. 4. Chemical analysis. 5. The conduct of suspected persons. 1. The Symptoms. — In most cases of poisoning the symptoms appear suddenly, in a person in good health, soon after the taking of food, drink, or medicine, and they run a rapid course towards a fatal termi- nation. The sudden appearance of the symptoms affords a slight presumption in favour of poisoning, fo)*, when administered, as poisons commonly are in criminal cases, in huge doses, the symptoms soon show themselves. But, on the other hand, when given in small and repeated doses, the invasion of the symptoms is often gi-adual. It must also be recollected that many diseases set in suddenly. This is true of many cases in almost all severe epidemics, as in plague, cholera, and yellow fever ; typhus fever also, and the febrile exanthemata — small-pox, scarlatina, and measles — show themselves suddenly with severe symptoms of indis- position. Many diseases of the more important organs also set ia sud- denly ; such as perforation of the stomach or intestines, and rupture of other important viscera, organic diseases of the heart, and apoplexy. The occurrence of the symptoms in a person in good health, also affords only a slight presumption in favour of poisoning ; for, on the one hand, many acute diseases make their attack without any previous impairment of health ; and, on the other, it is not unusual to administer poison to a person already suffering from i lines?, or to give a deadly SYMPTOMS. ■ 305 poison to a person whose health has been previously undermined by the administration of a less-active substance {e g. acetate of morphi.a or strychnia after tartar-emetic, as in Cook, the victim of Palmer). The appearance of the symptoms soon after the taking of food, drink, or medicine, affords a somewhat stronger presumption ; for all the more active poisons when given in large doses, especially if the poison be very soluble, act with great promptitude. On the other hand, it must be borne in mind, that vomiting and other symptoms of indisposition often manifest themselves after a meal containing no unwholesome substance; that apoplexy may follow a full meal; that rupture of the stomach, when its coats are softened by previous dis- ease, would naturally take place while the organ was distended with food ; that English cholera is often c:aused by unripe fruits, putrid meat, or other unwholesome ingesta ; and that a large draught of cold water, swallowed while the body is heated, may produce instant death. The probability derived from the symptoms occurring soon after a meal would be greatly strengthened if other persons partaking of the same meal were similarly affected ; but, at the same time, too much importance should not be attached to the absence of such effects; for the person in whom the symptoms have manifested themselves may have partaken of some dish or part of a dish, or of some wine or drink which the others may not have tasted. The attack of several persons by severe symptoms at or about the same time, and soon after a meal of which all have partaken, may be considered as the strongest possible presumption of poisoning either by the food itself, or by some accidental or intentional admixture. If the symptoms are those of simple irritant poison, it will not be possible to determine by the symptoms alone which alternative is the true one ; but they may happen to be so characteristic as at once to point to the very poison which has been administered. The value of this coincidence will be felt to be very considerable if it is borne in mind that none but epidemic diseases of the more severe kind are likely to attack seA^eral persons at the same time. It may be doubted even whether Asiatic cholera, in any one instance, has seized two or more members of a family so nearly at the same time, and at the same interval after a meal of which they had all partaken, as to give rise to a suspicion of poisoning. The only other diseases which are known to occur simultaneously, or at about the same time in severel persons, are imitative convulsive disorders; and these are generally confined to females. The simultaneous fatal attack of several persons in the same place, or on the same mission, in the absence of any proof that they had par- taken of the same food, would furnish a strong presumption of poison- ing. Thus, the death in one night of four of the eight peers selected to represent the Scottish nation at the nuptials of Queen Mary with the Dauphin of France, in 1558 (Lord Fleming at Paris, Bishop Eeid, the Earl of Rothes, and the Earl of Cassilis at Dieppe) very naturally gave X 306 • EVIDENCE OF POISONING. rise to a suspicion of poisoning ; especially as the refusal of the Scottish deputies to grant the crown matrimonial to the bridegroom had given great offence to the French court.* A suspicion of poisoning is often successfully rebutted by reference to the fact, that neither food, drink, nor medicine has been taken for hours before the commencement of an illness, f It must not, how- ever, be too hastily assumed that, because no food or medicine w^as swallowed before the symptoms set in, those symptoms are not due to poison ; for poisons have been introduced into the anus or vagina, poured down the throat of a drunken or sleeping person, or inserted into the external ear. The rapid course of the symptoms towards a fatal termination is also an extremely fallacious evidence of poisoning ; for many cases of poisoning end fatally after a considerable interval, and many acute diseases lun a very quick course. All the characters now mentioned are, therefore, to be received with caution, and cai-efully weighed against each other. The joint occur- rence of two or more of them would strengthen the probability ; and the coincidence of all of them, though not decisive, would justify a strong suspicion. Thus, if a person in perfect health, soon after taking food, were attacked with severe and continued vomiting and purging, and died within twenty-four hours, a strong suspicion would naturally arise that the food had contained some poisonous substance ; and the suspicion would be greatly strengthened if other persons who had partaken of the same food were similarly affected. The poison might have been added to the food, or the food itself might have had poison- ous properties ; but the probability of poisoning in one of these two ways is very strong ; and the inference would be almost irresistible if it could be shown that the person affected had never suffered in the same way before, and that neither English nor Asiatic cholera was prevailing at the time. 2. The Post-mortem Appearances. — The evidence from post- mortem appearances is, as a general rule, even less decisive than that afforded by the symptoms. It is true that there are poisons which leave in the dead body unmistakeable signs of their action: such as the mineral acids which stain and corrode the parts with which they come into contact, and oxalic acid in strong solution which corrodes the lining membrane of the gullet and stomach. Very characteristic appearances are also sometimes produced by corrosive sublimate, which, being decomposed by the secretions and membrane of the stomach, leaves a slate-coloured deposit of finely divided mer- cury ; and by arsenious acid, which is changed into the yellow sulphide by contact with sulphuretted hydrogen, the product of putrefaction, or clings as a white patch to the mucous membrane, Orpiment, and Scheele's green, and the salts of copper, also leave characteristic stains. ♦ Sharpe's Peerage— Marquis of Allsa. f For Illustrations see Christison ' On Poison/ p. 53. POST-MOETEM APPEARANCES. " 307 Vegetable poisons are also sometimes identified by seeds, or fragments of leaves left in the alimentary canal. Other poisons, again, belonging both to the class of irritants and to that of the narcotico-acrids, excite so intense an inflammation in the mucous membrane of the stomach and intestines as to give rise to a strong suspicion ; such intense inflammation being of rare occurrence in disease. Less degrees of inflammation being of common occurrence in persons who have died a natural death, would not of themselves justify a suspicion of poisoning ; and the same remark applies to those appear- ances of congestion in the brain which often result from the action of the narcotics and narcotico-acrids, such congestion being of common occurrence in simple apoplexy, in ursemia, and in many forms of death not originating in the brain. The negative evidence from post-mortem appearances has the same force with the positive evidence. Thus the absence of corrosion in alleged cases of poisoning by corrosives would serve to disprove the charge ; the absence of inflammation, after the alleged administration of an irritant or narcotico-irritant poison, to render the charge highly improbable ; and the absence of congestion of the brain, in a case of imputed narcotic poisoning, would afford a lower presumption against the exhibition of such a poison. Formerly undue importance was attached to an unusual blackness or lividity of the skin as evidence of poisoning; and the same remark applies to the early occurrence of putrefaction. There is no reason to believe that either of these appearances is more common after death from poisoning than after other forms of sudden death ; and it is now well known that some of the mineral poisons, for instance arsenic and corrosive sublimate, preserve the parts with which they are in contact. The discovery of post-mortem appearances similar to those produced by poison, even thoug?i confirmed by the discovery of the poison itseltj would not prove that death has been caused by poison, for death might be produced by some other cause befoi'e the poison had had time to prove fatal. On the other hand, in several instances on record, a dead body has borne marks of severe external injury, or the internal organs have been found very extensively diseased, and yet the real cause of death was poison. This class of cases strongly enforces the caution insisted on at page 205, under the head of post-mortem inspection, viz., to submit every part of the body to careful examination. The absence of characteristic post-mortem appearances might be- come important in the very improbable event of poison being introduced into the body after death, with a view to inculpate an innocent person. The post-mortem appearances, then, do not furnish independent evidence in the case of any considerable number of poisons ; but they may serve to confirm, by their presence, the presumption drawn from symptoms or from moral evidence, or by their absence they may in- validate a charge prompted by malice. 308 EVIDENCE OF POISONIKG. 3. Experiments on animals. — There are many considerations which affect the value of the evidence derived from this source. Poisons are 'alleged not to produce the same effect upon animals as upon the human subject, and many examples of this difference have been put on record. They also require to be given in quantities altogether disprojiortionate to the difference of size. To this objection there is the obvious answer, that the animals generally selected for experiment, especially the dog and cat, have been proved to be similaily affected with man by all the poisons in common use. This observation obviously applies with equal force to that very numerous class of cases in which the domestic animals and poultry have partaken of poisoned food in common with man, or have eaten the matters rejected from the human stomach. It ought also to be borne in mind, that, in many instances of ex- periments on animals with substances supposed to contain poison, the speedy death of the animal, or its escape with impunity, affords suffi- cient evidence in the affirmative or negative, without minutely examin- ing the symptoms actually present. In the case of some poisons also, as, for instance, of strychnia, the effect is of that simple and marked kind, that it is likely to be present in all animals alike. In many cases again, both experimental and accidental, this objection has been obviated by the poison having produced similar fatal eflects upon more than one kind of animal, such as the dog, the cat, and the domestic fowl. Another objection to the evidence drawn from experiments on animals, applies to those cases in which the substance administered has been pre- viously rejected from the human stomach, or collected from the stomach and intestines after death. It is alleged that the animal secretions may be so vitiated as to prove poisonous, and the allegation is supported by the well-known experiment of Morgagni, made with bile taken from the stomach of a child who died in convulsions from tertian ague. The bile mixed with bread and given to a cock caused convulsions and death in a few minutes, and the same effect followed in two pigeons inoculated with this same substance. It is obvious that such an ex- periment as this made with the bile of a diseased subject can have no proper application to cases in which food rejected from the stomach of a healthy person under the influence of poison has been swallowed by animals and proved fatal. It is scarcely necessary to sta^ that experiments with substances re- jected from the stomach, or found there after death, may fail in con- sequence of the substances themselves not containing the poison, or from the poison having been decomposed, or previously rejected. In some cases of poisoning of animals by arsenic and by strychnia, good evidence of poisoning has been afforded by the fatal effect pro- duced on one animal by eating the flesh of another animal which had been poisoned. CHEMICAL ANALYSIS 309 When there is reason to believe that the quantity of poison contained in tlie matters to be submitted to experiment is small, small animals, such as rats or mice, should be chosen for the purpose ; and the frog has been lately recommended as particularly adapted to experiments with minute quantities of such poisons as strychnia. Leeches have also been pointed out as applicable to the same purpose. In experimenting on larger animals which vomit their food, it is ex- pedient to guard against the rejection of the poison from the stomach by securing the gullet with a ligature. In the case of the greater number of poisons the necessity of experi- ments on animals is altogether superseded by the much higher certainty which attaches to chemical analysis ; bat as the tests for some of the vegetable poisons are uncertain, such experiments, performed with care, are valuable, and have been admitted as evidence. Experiments on animals have also been resoi-ted to, in order to de- termine some physiological questions raised in cases of poisoning ; such as, the shortest time within which a dose of prussic acid may prove fatal^ or the possible absence of marks of inflammation in the stomach after poisoning by some substance, such as corrosive sublimate, which usually occasions well-marked post-mortem appearances. 4. Chemical Analysis. — This form of evidence, though not abso- lutely necessary when the symptoms, post-mortem appearances, and circumstantial evidence confirm each other, is always of the first im- portance. The poison may be discovered in the living person by tests applied to the urine, to the blood abstracted by bleeding, cupping, or leeches, or to the serum of a blistered surface ; or it may be detected in the dead body in the blood, flesh, viscera, and secretions. In both these cases the discovery of the poison affords conclusive evidence of its administration. The discovery of a poison in the substances rejected from the stomach or voided by the bowels, or in the contents of the stomach and bowels after death, or in articles of food or medicine of which the sufferer has partaken, is open to certain objections presently to be mentioned. Objections may be urged against the sufficiency of the evidence drawn from chemical analysis on each of the three suppositions, that poison has been detected, that it has not been detected, or that it has been found in very small quantity. On the supposition that a poison has been found in the matters dis- charged during life, or found in the alimentary canal after death, or in articles of food or medicine, there is the one objection, that it may have been accidentally mixed with it, or fraudulently, in order to inculpate an innocent party, in which case the evidence must be sup- ported by proof that this could not have happened. On the supposition that a poison has not been found in any of the substances submitted to analysis, it does not follow that a poison has not been taken ; for in the case of a meal actually containing poison, and being followed by symptoms of poisoning, the articles submitted to 310 EVIDENCE OF POISONING. analysis may not contain the poison, though some other portion of the meal may have been adulterated with it. The poison may even be so unequally distributed through a single dish that the part examined may not contain any poison, though other parts of it do. Thus, the poison may be in the gravy, and not in the meat itself, or it may be sprinkled only on the outside of the joint. Again, when we are seeking for a poison in the contents of the stomach and intestines, we may fail to detect it because it had been rejected, or evacuated, ab- sorbed, decomposed, or evaporated ; or because it belongs to that large class of vegetable poisons which we have not yet found the means of discovering with certainty. The poison is most likely to be rejected or evacuated when it belongs to the class of irritants, absorbed when it is in a fluid state or soluble, decomposed when it belongs to the animal or vegetable kingdom. Insoluble substances, or those that are sparingly soluble, such as arsenic, may often be detected in the stomach and intestines after repeated vomiting and pui'ging, for they adhere as powder to the mucous coat, and are enveloped by the tenacious secretion thrown out about them in consequence of the inflammation to which they give rise. In cases of disinterment, poison, though it may have been the cause of death, and may have existed in the body at the time of death, may exude through the textures, or be evaporated, or so completely decomposed, that no trace of it is to be found. This observation does not apply to the mineral poisons, in a solid form, for though they may undergo change in consequence of the decay of the textures, they are merely transformed but not destroyed. Thus arsenious acid may combine with the nascent sulphuretted hydrogen given off during the decomposition of the stomach, and be converted into the yellow sulphide of arsenic, and corrosive sublimate may by the mere contact of the mucous membrane be converted into calomel, or pure finely divided mercury. Among the animal poisons, cantharides, and, among vegetable poisons, opium, may be mentioned as undergoing little change from the decay of the textures. It is scarcely necessary to add that cases are by no means of rare occurrence in which malicious or mistaken imputations of poisoning are cleared up by the non-discovery of poison in the matters supposed to contain it. When poison has been discovered in very small quantity, the objec- tion is sure to be advanced that the quantity found was not suffi- cient to account for death. To this objection there is the obvious reply that the quantity of poison found must always fall short of the quantity actually taken : for it is only a part of the matters vomited or otherwise expelled from the body, of the contents of the alimentary canal after death, or of the blood tissues or viscera of the body which is submitted to analysis. The discovery, therefore, of a quantity of poison insufficient to destroy life is scarcely even a presumption that the substance was not administered in a poisonous dose ; but it is also QUANTITATIVE ANALYSIS. 311 consistent with the supposition that the poison was given in a medicinal dose or doses, for purely medical purposes. But the value of chemical analysis as an evidence of poisoning is not limited to the discovery of the poison in larger or smaller quantity in some single substance submitted to examination ; for by the comparison of one analysis with another, important light is sometimes thrown upon the manner of administration, and means are afforded of demon- strating the innocence or guilt of a suspected or accused party. An interesting case given by Christison on the authority of Dr. Alison will serve to illustrate this position. A bowl of porridge eaten by the deceased female tor breakfast was found to contain arsenic. The chemical analysis showed that the poison was not mixed with the store of meal, but only with the portion of meal used in making the porridge. As it appeared from other circumstances that the poison must have been mixed with the meal in the morning before any stranger entered the house, the husband (the only other inmate) was convicted of the murder. An instance of an opposite kind is quoteid by the same author from Barruel. The arsenic was found mixed with a large mass of flour, as well as with the part used in making bread. As the poison was not likely to have been mixed with a criminal intent, with so large a portion of the flour, the admixture was inferred to have been made with some innocent purpose. The wheat had probably been intended for seed, was mixed with arsenic to destroy insects, and had been sent, in mistake, to the mill.* In several cases of poisoning by the corrosive acids, the examination of the clothes of the suspected murderer conjointly with the body of his victim has led to a conviction. The cases just referred to are examples of qualitative analysis. The two following cases illustrate, in an equally striking manner, the use which may sometimes be made of two or more analyses directed to determine the quantity of poison present in the several substances sub- mitted to examination, Mr. Hodgson, a surgeon, was tried at Durham Autumn Assizes, in 1824, for attempting to poison his wife. It was proved that he had substituted corrosive sublimate for calomel and opium in pills pre- scribed by her physician. This he attributed to a mistake committed while he was intoxicated. It was further proved that a laudanum draught, also ordered by her physician, contained corrosive sublimate. This, too, the prisoner explained by alleging that he had mistaken for the water-bottle an injection of corrosive sublimate which he had previously prepared for a sailor. But on submitting the draught and the injec- tion to chemical analysis, the former was found to contain fourteen grains to the ounce, while the latter contained only five grains to the ounce. t * Christison ' Ou Poisons,' p. 15. t For a full report of this interesting case see the • Edin, Med, and Surg. Journal,' vol. xxii. p, 438, 312 RULES FOR MEDICO-LEGAL EXAMINATION. Samuel Whalley was indicted at York Spring Assizes, in 1321, for maliciously administering arsenic to Martha King, who was pregnant by him. But it appeared that of the tarts in which the arsenic was alleged to have been administered, the portions eaten could not have contained more than ten gi-ains, while the matters alleged to have been vomited, contained even after repeated attacks of vomiting, fifteen grains.* 5. The conduct of suspected persons. — Great importance is very properly attached, in trials for poisoning, to the conduct of the prisoner, before, during, and after the illness of the deceased. The prisoner is often proved to have become possessed, without adequate motive, of a knowledge of poisons and their properties ; to have purchased poison under false pretences ; to have compounded medicine, or prepared food for the deceased ; to have sought opportunities of administering medicine or food ; to have shown great haste in disposing of matters which might have been exaniined ; to have placed obstacles in the way of obtaining proper medical assistance ; to have made arrangements for keeping near relatives, and other inconvenient witnesses at a distance ; to have made huiTied arrangements for the funeral ; to have made opposition to an examination of the body ; perhaps to have tampered with the matters reserved for analysis. Such acts as these, some of which are likely to fall under the notice of a medical attendant, will have to be carefully weighed by the jury, together with such other items of general or circumstantial evidence as the existence of an obvious motive or inducement to the crime, and the previous state of mind of the deceased as affording a probability, or the reverse, of suicide. This part of the subject of death by poison may be usefully brought to a close by a summary of the leading precautions to be observed in conducting medico-legal examinations in cases of suspected poisoning. RULES FOR MEDICO-LEGAL EXAMINATION IN CASES OF POISONING. The chief points to be attended to in cases of suspected poisoning are the following : 1 . The state of the patient before the commencement of the symp- toms, whether in good health or suffering from illness — the time at which the symptoms began, and at what interval after a meal, or after taking food, drink, or medicine — the nature of the symptoms, their order and time of occurrence, and the period of the commencement of any new symptom or train of symptoms ; whether the symptoms increased steadily in severity, or alternated with intervals of ease, and whether the exacerbations corresponded with a repetition of the food or medicine, or followed the use of any new article of food or medicine — also the character of any substances which may have been rejected from * ' Edin, Med. and Surg. Journal,' vol. xxix. p. 19, CLASSIFICATION OP POISONS. 313 the stomach, or have passed from the bowels. If the case terminated fatally, the exact time of the death should be noted down, if the person is found dead, the time at which he was last seen alive should be ascertained. 2. When the symptoms of poisoning have shown themselves soon after a meal, minute inquiries should be made as to the manner in which the several dishes used at the meal have been prepared ; the vessels used in the preparation of the food should be inspected, and their contents, if necessary, be preserved ; suspicious powders or liquids found in the house should also be sealed and kept. If several persons have partaken of the same meal care should be taken to ascertain what articles were taken by those who suffered, and by those who escaped, and in what quantities, and whether the same articles of food had been pi'eviously taken without any bad effect by the persons attacked. 3. The vomited matters must be carefully collected, and removed from clothing, furniture, &c., on which they may have been rejected ; and portions of the dress, furniture, or flooring may, if necessary, be reserved for examination. 4. In performing a post-mortem inspection, a note should be kept of the time at which the inspection is made, and all the precautions insisted on (p. 205) should be carefully observed. The state of all the internal viscera must be noted, and especially of the mouth, tongue, and fauces, of the larynx, oesophagus, stomach, and intestines. In removing the viscera, care should be taken to place them on a clean surface, and to preserve them in clean vessels, and the same caution applies to the contents of the stomach and intestines. If the medical man has occasion to transmit the contents of the stomach and bowels, the blood, or other fluids of the body, or portions of the viscei-a, or other substance supposed to contain poison, to a chemist for analysis, it must be carefully sealed, so as to prevent the possibility of the substance being tampered with during its transit. 5. In performing a chemical analysis, measures should be taken to pi'eserve the identity of the substances submitted to examination. While the analysis is going forward they must not be let out of the sight and custody of the operator, and during his absence they should be preserved under lock and key. 6. In conducting correspondence in reference to pending medico- legal analyses, letters should be doubly secured first by wafer or gum, and then by seal; and letters should be posted, if possible, by the writer. CLASSIFICATION OF POISONS. There are only two principles of classification which commend them- selves to the judgment of the toxicologist, as logically correct and practically useful. The one arranges the several poisonous agents 314 CLASSIFICATION OF POISONS. according to the source whence they are obtained ; the other, in ac- cordance with their action on the system. When the first principle of classification is adopted, poisons are arranged in three principal classes — mineral, vegetable, and animal ; when the second is preferred, they are also arranged in three leading classes — irritants, narcotics, and narcotico-acrids. A classification based solely on the source from which the poison is obtained is open to the very obvious objection that though almost all the substances derived from the mineral and animal kingdoms are irritants, those derived from the vegetable king- dom comprise poisons belonging to each of the three classes, the ii-ritant, narcotic, and narcotico-acrid. On the other hand, a classifica- tion based on the mode in which poisons affect the system is subject to the inconvenience of separating, in the case of the considerable class of vegetable poisons, substances derived from the same kingdom of nature, and distributing them through the three classes of irritants, narcotics, and narcotico-acrids. As, then, these two modes of classification are open to nearly equal objection, on the ground of logical consistency, our choice will naturally be determined by considerations of utility ; and it is obvious that these greatly preponderate in favour of an arrangement which places side by side those poisonous substances which produce a similar effect upon the system. The most useful classification of poisons, therefore, is that founded on their mode of action, and this is the one now generally adopted. According to the received classification, poisons may be distributed into three principal classes — irritants, narcotics, and narcotico-irritants. The poisons belonging to the first class excite inflammation in the parts with which they come in contact, and give rise either to the constitutional disturbance which attends on high inflammatory action, or to the nervous symptoms attendant on severe and extensive injury to impoi-tant organs of the economy ; those belonging to the second class affect the nervous centres, producing coma, delirium, convulsions, and other allied symptoms ; and those of the third class combine, in varying degrees and proportions, the symptoms proper to the two classes. After a careful consideration of the many and conflicting difficulties which surround the attempt at a classification of poisons, I see no reason to depart from the division into irritants, narcotics, and nar- cotico-acrids. Distinct chapters will be devoted to these three leading classes, in which chapters the several poisons belonging to each class will be distributed into sub-classes, in accordance chiefly with their mode of action. The lelative importance of the three classes of poisons may be inferred from the number of cases in which, one year with another, they prove fatal. In the five years, 1852 — 56, the number of deaths by poison amounted, on an average, to 401, of which 133 were due to poisons not distinctly specified. Of the remaining 268, 90 were ORDER OF PRECEDENCE OF POISONS. 315 irritants, 175 narcotics, and 3 narcotico-acrids. 82 cases of suicidal poisoning were distributed as follows : — Irritaut poisons, 27 ; narcotic poisons, 54 ; narcotico-acrid poisons, 1. It appears, then, that two deaths by narcotic poisons occur for one death by the irritants, while deaths by narcotico-acrid poisons are of comparatively rare occurrence. The principal poisons, arranged in the order of the frequency with which they prove fatal, take rank as follows : — Laudanum, opium, morphia, and Godfrey's cordial, 141 ; prussic acid, essential oil of bitter almonds, and cyanide of potassium, 34 ; arsenic, 27 ; salts of lead, 23; mineral acids, 15; oxalic acid, 13; mercury, 10; strychnia and nux vomica, 2.* * ' Nineteenth Annual Report of the Registrar-General,' p. 164, 316 CHAPTER II. IRRITANT POISONS. Substances which inflame the parts to which they are applied are said to act as irritants to those parts ; and substances which, in traversing the alimentary canal, inflame the organs with which they (^ome in contact, are also termed irritants ; and, with the exception indicated when defining the term poison, of hot and cold water, and such articles as pins, needles, and powdered glass, may claim to be admitted into the list of irritant poisons, if they prove in any instance fatal to life, or productive of symptoms of great severity. The class of irritants comprises animal, vegetable, and mineral substances ; it contains a greater number of individual poisons than the two other classes of narcotics and narcotico-acrids put together ; and it also contributes largely to the list of cases of poisoning. It accounts for one-third (90 in 268) of the annual deaths from ascer- tained poisons; of which third more than two-thirds (61 in 90) were metallic irritants, one-third (27 in 90) mineral and vegetable acids (principally the sulphuric and oxalic), while all the remaining irritants i'ormed but an insignificant fraction of the whole. So considerable a class of poisons must needs comprise several sub- classes. Three groups, at least, admit of distinction and separation. There is the well-marked group of simple corrosive poisons, which destroy life by a direct destructive action on the mucous membrane of the alimentary canal ; the equally well-marked group which proves fatal by the irritation occasioned in the same parts ; and a third group which add to local destruction or irritation, peculiar remote effects not due to the local injury they inflict. To the first group belong the mineral acids, the caustic alkalis, and their carbonates, oxalic acid when given in strong solution, and the more soluble salts of the metallic poisons, mercury, antimony, zinc, and tin. To the second group belong the principal vegetable irritants, some of the alkaline salts used in medicine, and the less active metallic poisons. The third group comprises oxalic acid and the soluble oxalates ; the metallic irritants, arsenic, mercury, antimony, lead, and copper ; the metalloidal elements, phosphorus, and iodine; and, as a product of the animal kingdom, cantharides. Any classification based solely upon the mode of action of these poisons must recognize these three classes; but as great inconvenience would arise from separating oxalic acid from the other vegetable acids, SYMPTOMS. 317 or corrosive sublimate from the less soluble and non-corrosive salts of mercury, a mixed arrangement, recognizing mode of action, on the one hand, and similarity of composition and origin on the other, will best meet the practical requirements of the case. Such a mixed arrangement is given at the end of the present chapter. • The symptoms caused by irritant poisons, as a class, are buniing pain and constriction in the throat and gullet ; acute pain, increased by pressure, in the pit of the stomach ; intense thirst ; nausea and vomiting, followed by pain, tension and tenderness of the entire abdomen ; and purging attended with tenesmus, and frequently with dysuria. The constitutional symptoms vary with the intensity of the irritation, and the interval which has elapsed since the administration of the poison, being at one time those of collapse, at another of inflam- matory fever. The mode of death also varies. The patient does not rally from the first shock to the nervous system, or he dies in strong convulsions, or he is worn out by protracted suffering, or he is starved through the injury sustained by the gullet and stomach. These symptoms A^ary in severity, and in the period and order of< their occurrence, with the quantity of the poison, with its solubility, and with the full or empty state of the stomach ; but In a more marked manner, according as it is corrosive or simply irritant. When the poison is sparingly soluble, as in the case of arsenious acid, the pain in the several parts specified is not felt immediately on swallowing it, but after an interval more or less considerable, and, occasionally, the pain and sense of constriction in 'the throat and gullet are absent; or they follow the other symptoms instead of preceding them, in conse- quence partly of the frequent acts of vomiting, and partly of the repeated contact of the vomited matters with the upper portions of the tube ; but when the poison is corrosive, and very soluble, as is the case with the mineral acids, oxalic acid, the pure alkalis, corrosive sub- limate, and the chlorides of tin, zinc, and antimony, the pain is felt as soon as the poison comes in contact with the paiis affected, and occurs almost simultaneously in the throat, fauces, gullet, and stomach, whence it extends rapidly to the entire abdomen, and is soon followed by vomiting and purging. The action of the corrosive and more soluble irritant poisons is also followed by copious vomiting and purging of blood, which does not take place at all, or to a more limited extent, in the case of the simple irritants. In poisoning by the corrosives, also, the upper part of the windpipe is frequently attacked with inflammation, giving rise to hoarseness, wheezing respiration, and harassing cough, and often ending in suffocation. The Morbid Appearances caused by the irritants are those of corro- sion, followed by inflammation and its consequences, when the poison is a corrosive, and those of inflammation and its consequences when the poison is a simple irritant. The corrosions may be confined to small spots, or they may extend over a large surface ; they may be limited to a removal of portions, more or less considerable, of the lining mem- 318 IRRITANT POISONS. brane of the gullet and stomach, or all the coats of those organs may be destroyed. The parts injured may become the seat of perforations of greater or less extent, and considerable portions of the organs them- selves may even be discharged by vomiting or by stool. The simple irritants, and the corrosives beyond the corroded part, give rise to inflammation more or less severe, followed by its usual consequences. In some cases there is merely increased vascularity, in others deep redness ; the surfsice is covered with a tenacious secretion, and the cavity filled with a glairy mucus. The coats are found thick- ened with the intensity of the inflammation ; dark, as if gangrenous, from the extravasation of blood into the mucous membrane and beneath the submucous tissue ; softened; but occasionally hard and shrivelled. Vessels filled with dark blood are sometimes found ramifying minutely over the surface, which in other instances is studded with black points. Sometimes the mucous membrane is found ulcerated, and more rarely it is gangrenous. These appearances are not confined to the stomach, but are found in the fauces, and oesophagus, and in the duodenum. The appearances in the rest of the small intestines are those of acute inflammation, with ulceration and softening of the mucous membrane ; ulcers are also found in the large intestines, and excoriation of the anus. In some cases there are traces of inflammation in the mucous membrane of the larynx and air passages ; and the corrosive poisons often produce in the gullet a peculiar wrinkled and worm-eaten appearance, due to the contraction of the longitudinal and transverse fibres, and the removal of patches of epithelium. (See figures 12, 13, and 14, p. 338.) The treatment of poisoning by the irritants as a class consists (irrespective of the administration of the appropriate antidote) in the prompt use of the stomach-pump (if not contraindicated by extensive destruction of the soft parts), or of emetics of ipecacuanha, common salt, or mustard, assisted by copious draughts of warm water, and by tickling the fauces ; and, when the poison is discharged, by the free use of milk and water, or of oily and mucilaginous drinks. Castor-oil mixed with milk is the best aperient. The after-treatment must be determined by the state of the patient and the special symptoms present in each case. Bleeding, if indicated by the state of the patient, is to be commended as removing part of the poison absorbed into the blood. Several of these symptoms and post-mortem appearances are not peculiar to poisoning; and there are some common and familiar diseases, as English and Asiatic cholera, acute inflammation of the stomach or intestines, rupture of the stomach or intestines, or of other viscera of the abdomen, in which one or more of the symptoms of irritant poisoning are present in a marked form. They may also be produced by drinking hot or cold water ; and authors have been at some pains to show that simple distension of the stomach, vomiting and purging of blood, colic, strangulated hernia, and obstruction of the bowels, diarrhoea, and dysentery, have some symptoms in common with ordinaiy cases of irritant poisoning, and may still more nearly resemble certain excep- SIMILAR SYMPTOMS CAUSED BY DISEASE. 319 tional cases. Though the importance of the objections founded on this possible resemblance of disease to poisoning has certainly been exaggerated, it may be well to point out some of the leading features- in which the diseases in question differ from the usual effects of irri- tant poisons. In English cholera, the evacuations very rarely contain blood, and there is no pain and constriction in the throat, except occasionally as the result of constant efforts to vomit. The disease prevails chiefly in summer and autumn, and is rarely fatal. In Asiatic cholera, too, dis- charge of blood is a very rare occurrence, though the evacuations sometimes have a port- wine tint; and the pain and constriction of the throat are wanting. In both diseases the purging follows the vomiting much more rapidly than in cases of poisoning. The irritant of which the operation most nearly resembles these diseases is arsenic ; and during the prevalence of both forms of cholera the effects of arsenic have been mistaken for disease, without seriously affecting the reputation of the medical attendant. Acute inflammation of the stomach, except as the result of drinking hot or cold water, or as the effect of some irritant substance, is a very rare disease, and is not accompanied either by pain and constriction in the throat, or by diarrhea. Acute inflammation of the bowels affects their peritoneal covering, and is attended with constipation. Distension of the stomxxch, though an occasional cause of severe suffering and of sudden death, does not admit of being mistaken for the effect of a class of poisons of which vomiting is a leading symptom. A full stomach would, in itself, furnish a strong pi-esumption against irritant poisoning. Rup- ture of the stomach occurring, as it often does, during or directly after a meal, and through an effort to vomit, followed by sudden and violent pain, by collapse, and by death instantly, or in from four or five to less than twenty-four hours, might naturally raise a sus- picion of poisoning, which nothing short of a post-mortem examination can set at rest. The same observation applies to a rupture of the inner coat alone — a case of very rare occurrence — and to rupture of the intestines, and of the other viscera of the abdomen. All these acci- dents may be followed by vomiting, with excruciating pain, and extreme tenderness of the abdomen, cold skin, feeble pulse, and symptoms of collapse, with death within twenty-four hours. The effect of drink- ing hot water differs from that produced by the simple corrosives, chiefly in the absence of characteristic stains, and the negative result of an analysis. The drinking of cold liquids sometimes causes vomiting and purging, and other symptoms allied to those of irritant poisoning ; and, in the absence of a complete history of the case, it may be necessary to resort to the negative evidence afforded by the result of an analysis. Of vomiting and purging of blood it will be sufficient to remark that they ai'e not accompanied by urgent symptoms suggestive of the action of poison ; of diarrhcea and dysentery that, in by far the greater 320 IRRITANT rOISONS. number of cases of poisoning discharges from the bowels are asso- ciated with vomiting ; and of colic, strangulated hernia, and obstruc- tion of the bowels, that they are attended l)y constipation, and that the vomited matters are often feculent. The post-rnortem appearances in cases of irritant poisoning are not always characteristic ; and it is true of the more common appearances, as of some of the more usual symptoms, that they might have been occasioned by disease. The appearances in the stomach commonly specified as answering to this description are — Redness of the Mucous Membrane ; Gangrene and Lividity ; Softening ; Ulceration ; and Per- foration. Redness of the mucous membrane may be produced by colouring matter ; but when it is due to blood contained in the vessels, it may be traced to subsidence of the blood after death, or to the blood being driven into the small vessels by the contraction of the arteries, or to transudation through the peritoneal covering of the liver or spleen ; or to congestion in cases of sudden death, especially in the various forms of death from apnoea, when it often occurs in large bright patches ; or lastly, it may be the result of thj^t flow of blood to the mucous coat of the stomach which takes place during the process of digestion. Sometimes, too, a remarkable redness of the stomach is found after death without any symptoms occurring during life to account for it. Hence, mere redness of the mucous coat of the stomach, even when it does not occur on the most depending part, is not to be regarded as a proof of inflammation. But when the redness of the mucous membrane is combined with softening, putrefaction not having set in ; when the membrane itself is covered with a thick and tenacious mucus ; when it is opaque, so that dissected off and stretched over the finger, the finger is not visible ; the redness may be certainly attributed to inflammation, especially if it cannot be traced to mere subsidence of blood, and the larger veins are not injected. The same remarks apply also to the intestines. Gangrene and Lividity . — Gangrene of the mucous membrane is of very rare occurrence, except as the consequence of long-continued pressure in cases of hernia. Gangrene of the mucous membrane from acute inflammation has been described by authors of reputation ; but there is no doubt that a dark appearance due to infiltration of blood into its texture has been often confounded with it. This lividity of the mucous membrane presents itself in as many shapes as the redness just described ; in points, striae, ramifications, and patches of greater or less extent. In some instances the vessels, to their smallest branches, are filled with black blood ; in others, the mucous membiane is thickly studded with black points ; and in others, again, thick coagu- lated blood is poured out into the sub-mucous cellular membrane. These appearances, but especially the latter, are most common in poisoning by the mineral acids and by oxalic acid. There is reason to believe that these appearances (with the exception of the injection of ULCERATION. 321 the vessels with dark blood, which is sometimes seen in post-mortem softening) are never found in the stomach as the result of disease, but that they are always due to the action of violent irritants. They are, however, sometimes met with in the intestines in acute dysentery and enteritis. This livid colour of the mucous membrane is distinguished from melanosis by the latter being arranged in regular well-defined s[)0t5, without thickening of the mucous membrane, or signs of sur- I'ounding inflammation. Softening. — The mucous membrane is sometimes softened, some- times hardened by the action of poisons. When softened, it is either through the action of the con-osives, or it is the effect of inflammation without corrosion. Softening is also one result of disease during life, and of the action of the gastric juice after death. As the soft- ening fiom coiTOsion is attended with more complete destruction of surrounding parts, with characteristic changes of colour, and with signs of acute inflammation, and as the softening due to the action of the non-corrosive irritants is attended by mai'ks of acute inflammation, the softening due to these two causes will be readily recognized ; and the fact that the softening from disease is not preceded by any charac- teristic symptoms will sometimes assist the diagnosis. Ulceration. — Ulcers of the stomach may arise either from the action of poison, or from disease. Those due to disease are either the result of cancer of the stomach, which is readily recognized, or they occur in stomachs which, in other parts, present a healthy appearance. Open ulcers, or the scars of ulcers, are present in about one dead body in ten. In about one-fifth of the cases there is more than one ulcer. The ulcer is rarely much smaller than a fourpenny piece, or larger than a crown-piece, but it may attain a diameter of five or six inches. Its shape is usually round or oval ; and it presents the appearance of a shallow but level pit, with a sharp, smooth, vertical edge, as though it had been punched out ; and as the circular opening in the sub- mucous areolar tissue is smaller", and the aperture in the pe)-itoneum, if the ulcer perforates, still more minute, the ulcer has the appearance of a cone, with the base directed inwards. The mucous membrane and the areolar tissue are somewhat thickened by exudation of lymph ; and it is not unusual to find adhesions to surrounding parts. In some cases there is little or no appearance of inflammation in the parts sur- rounding the ulcer ; in most instances the edges are thickened and raised, and the thickening sometimes extends to a circle of half an inch or an inch ; and occasionally the surrounding parts are described as " a thick brawny mass," sometimes mistaken for cancer ; or they are stated to be blackened. In more than a third of the cases the ulcer occupies the posterior surface of the stomach, and more than three- fourths of the ulcers occur on the posterior surface, on the lesser curvature, or near the pylorus.* When due to poison the ulceration * See Dr. Brinton, ' On the Pathology, SjTuptoms, and Treatment of Ulcer of the Stomach,' p. 4. Y 322 IRRITANT POISONS. is the result of a more intense inflammation tlian that wliich attends the more chronic ulceration of disease ; and the ulcer is often found discoloured, as in the case of nitric acid and iodine, or covered with a white powder, as in the case of arsenic, or coated with a substance resulting from the decomposition of the poison, such as the black powder (minutely divided mercury), formed by the decomposition of corrosive sublimate, or the yellow sulphide of arsenic formed during the process of putrefaction after death. Those occasional appear- ances, added to the intensity of the inflammation, and the symp- toms during life, will render the distinction between idiopathic ulceration and that due to poisoning easy. Perforation of the Stomach mny arise, 1, from corrosion; 2, from inflammation, and consequent ulceration ; 3, from softening during life ; and 4, from the action of the gastric juice after deatli, 1. Perforation from Corrosion. — It is impossible to confound a per- foration due to the direct corrosive action of an irritant poison with any perforation arising from natural causes, acting either during life or after death. The state of the mouth, throat, and gullet, and often of the skin and clothes of the deceased will rentier the distinction easy. In many cases, too, the corrosive poison escaping into the cavity of the abdomen leaves traces of its action on the other viscera. 2. Perforation from Ulceration is of very rare occurrence. When caused by idiopathic inflammation, the surrounding mucous membrane is less highly inflamed, and neither stained nor covered with deposit, as in poisoning by the irritants. 3. Perforation from Softening of the coats of the stomach during life is not of rare occurrence. It most frequently happens in young females, from fifteen to twenty-five years of age, and often after slight symptoms of indisposition. The rupture generally takes place soon after a meal, more rarely as a consequence of strong sudden exertion, and is immediately followed by acute pain of the abdomen, and symp- toms of acute inflammation of the peritoneum. There is little vomit- ing, and no purging, but the patient dies in a state of collapse in from eighteen to thirty-six hours ; but in^some cases the fatal event is post- poned in consequence of the escape of the contents of the stomach being small in quantity, and the inflammation of the peritoneum limited in extent, or subacute in character. The aperture in the peritoneum is generally small, and the ulcer itself has the peculiar characters just described. In one-third of the causes the seat of the perforation has been the lesser curvature of the stomach ; in one-tenth, the pyloric extremity ; in about one-twentieth the posterior surface ; in the same number the cardiac extremity ; while in one-eighth of the cases there are two ulcers opposite to each other on the anterior and posterior surfaces of the organ, the first being the seat of the perforation.* The absence of marks of acute inflammation, and, in many cases, of * Consult Dr. Brinton's work just cited, and Dr. Taj'lor's essay in the ' Guy's Hospital Reports,' No. 8. CLASSIFICATION OF THE IRRITANT POISONS. 323 the discolourations characteristic of some of the irritant poisons ; the non-detection of poison in the stomach itself, or in the contents of the abdomen ; the sudden occurrence of pain ; the slight subsequent vomit- ing; the absence of diarrhoea; and the early occurrence of death, as compared with the period at which perforation following poison generally proves fatal, will make the distinction between this form of perforation and that due to poison easy. 4. Pei^foration from the action of the gastric juice after death has boen the subject of much controversy ; but the fact of its sometimes taking place has been placed beyond a doubt, by observations and experiments made both on men and animals. The seat of the opening is generally the posterior surface of the stomach, but it depends on the position of the body. The aperture may be of any size, from that of a shilling to that of the palm of the hand : and, in some instances, it has been found to occupy one-half of the stomach. It may assume any shape, and its edges are fringed, softened, and smeared with a dark pulpy mass, and the vessels of the stomach are sometimes found in- jected with dark blood. The viscera in contact with the opening sometimes undergo a» similar change. Occasionally there is more than one aperture. As there is no appearance of inflammation around the opening, it is impossible to confound this post-mortem change with the effect of an irritant poison. Perforation of the stomach due to the action of irritant poisons " would be attended by marks of acute inflammation, and by charac- teristic stains and deposits. Perforation of the intestines is of very rare occurrence in cases of poisoning, and perforation of the gullet still less common. Both are of occasional occurrence as the consequence of diseases not difficult to recognize after death. CLASSIFICATION OF THE IRRITANT POISONS. The following classification, which comprises all the more important divisions of irritant poisons, is in conformity with the principles already laid down in this chapter. It recognizes three leading classes, with numerous sub-classes — the leading classes being — 1. Simple Cor- rosives. 2. Simple Irritants. 3. Specific Irritants. 1. The class of Simple Corrosives comprises two sub-classes : — a. The mineral acids, h. The alkalis and their carbonates. These simple corrosive poisons are treated in two distinct chapters. 2. The class of Simple Irritants comprises : — a. The vegetable acids, of which the oxalic is the most important. This acid, though belonging to the class of specific irritants, is most conveniently included in the same chapter with the other vegetable acids, h. The salts of the alkalis and earths, c. Vegetable irritants in common use as purgatives, d. Other vegetable irritants not comprised in the fore- 324 CLASSIFICATION OF THE IIIUITANT TOISONS. going sub-classes ; among which savin is the most important, e. Pro- ducts of destructive distillation, such as dippels and fusel oil. /. Er- got of rye, and other diseased or decayed vegetable matters, g. Animal irritants, of which canthaiides is the most important, h. Irritant gases. 3. The class of Specific Irritants contains — a. Metalloidal poisons, iodine and its salts, and phosphorus, h. Metallic irritants, among which arsenic, mercury, antimony, lead, and copper, with their compounds and salts, are the most important. 25 CHAPTER III. MINERAL ACIDS. 1. Sulphuric acid, 2. Nitric acid. 3. Muriatic acid, 4. Mixtures and compounds of these acids. The mineral acids, as a sub-class of the large class of irritant poisons, are distinguished from most irritants by their strong corrosive proper- ties, and from all irritants except those of the next sub-class, alkalis and their carbonates, by their remote symptoms being due entirely to their energetic local action. They have no specific remote effects. In the years 1837 and 1838 one in fifteen of the fatal cases of poisoning were due to the mineral acids, pure or in a state of mixture. The whole number was 36, of which 32 were from sulphuric acid, 2 from nitric acid, mixed in one instance with laudanum, in another with aloes. The number of cases of poisoning by these acids has probably decreased both absolutely and by comparison with other poisons ; for in the five years 1852-1856, 77 cases only were registered, of which 73 were by sulphuric acid, 2 by nitric acid, and 2 by muriatic acid. Though poisoning by the mineral acids is, for obvious reasons, not likely to be a homicidal act, they are sometimes administered to adults in place of medicine, or poured down the throat while they are asleep or intoxicated : and more frequently to young children by their mothers or nurses. In mfants the act is most probably homicidal, in children either homicidal or accidental, in adults generally suicidal. The mineral acids have also been administered otherwise than by the mouth. One acid (the sulphuric) has been injected into the vagina, another (nitric acid) has been poured into the ear. The mineral acids, especially oil of vitriol, are also sometimes used to disfigure the person, or destroy the clothes, or to imitate the destructive action of moths. The Mineral Acids have the following familiar properties in com- mon:— they discolour, and, at the same time, corrode, or injure, the texture of black cloth; and they redden vegetable blues, and alter or discharge the colour of articles of dress. The symptoms common to the mineral acids are the following : — 326 MINERAL ACIDS. a burning pain in the mouth, throat, and gullet, occurring immediately after swallowing the acid; followed by excruciating pain in the stomach, eructations, constant retching, and vomiting of a brownish or blackish matter containing blood, coagulated mucus, flakes of epithelium, or portions of the mucous membrane of the stomach itself. The act of swallowing is painful, or even impossible, and there is intense thii'st. The bowels are costive, and the urine scanty or suppressed, and the patient is troubled with constant tenesmus and dysuria. The pulse is generally small and frequent, the respiration catching, and sometimes laborious, and the countenance expressive of intense anxiety. In some cases the acid passes into the windpipe, and causes a harassing cough, with croupy respiration, the accumulation of tenacious mucus dis- charged with difficulty, and a hoarse voice threatening instant suffoca- tion. The lips are shrivelled and blistered, or excoriated, or they present spots of the characteristic colour of the acid bordered with red, or there are discoloured streaks extending from the angles of the mouth to the chin. The inside of the mouth is white, shrivelled, and corroded, and the teeth loose and discoloured. The tongue is some- times white and polished, sometimes discoloured. The acid generally leaves distinct marks on the cheeks, neck, or fingers, as well as on the clothes; and the vomited matters, if rejected on a limestone pavement, cause effei-vescence. In fatal cases death is generally preceded by symptoms of collapse ; the intellectual faculties remaining clear to the last. Sometimes the patient dies convulsed, sometimes suffocated. Severe nervous symptoms, such as trismus, tetanus, epilepsy, and delirium are occasionally present, and rashes sometimes appear on the skin. The period at which death happens is very variable : it may take place as early as two hours, or at the end of days, weeks, or even months. When the patient survives for some days, the symptoms are somewhat modified. He is feverish ; has a dry skin and frequent pulse ; occasionally vomits his food and drink, mixed with flakes of tena- cious mucus, similar flakes being sometimes discharged from the bowels ; and suffers from salivation with fcetor of the breath. The belly is tense, the breathing short and difficult ; there are pains and spasms of the limbs ; digestion is impaired, all the functions of the body languish, the patient becomes extremely emaciated, and dies in a period varying from a fortnight to some months. Other patients recover imperfectly, to become dyspeptic, and valetu- dinarians for life. Rather less than half the number of cases recover completely. In some instances the poison does not reach the stomach, but affects the throat, gullet, and windpipe. In other cases the acid acts only on the windpipe, causing death by suffocation. The mineral acids have also proved fatal when introduced into the body otherwise than by the mouth ; as when injected into the bowels or womb, or poured into the ear. POST-MORTEM APPEARANCES. 327 The post-mortem appearances, common to the mineral acids, are the following : — The body externally has a healthy appearance. The lips, chin, and other parts of the body are marked by the action of the acid in the manner already described. The mucous membrane of the mouth is white, yellowish, or brownish, shrivelled and corroded ; and the same appeaiances extend into the throat. The epiglottis is sometimes contracted, sometimes swollen, the rima glottidis con- tracted, and the larynx inflamed. The gullet either presents the same appearance as the mouth and fauces, or it is highly inflamed, and lined with a coat of tenacious mucus, or its mucous coat is partially or wholly stripped off. (See fig. 13, p. 338.) Sometimes it presents the peculiar wrinkled and worm-eaten appearance shown in flg. 12. Occasionally the gullet entirely escapes. In rare cases it becomes the seat of ulceration, and is perforated. The stomach is usually distended with gas, and filled with a yellowish, brownish, or blackish glutinous secretion, which also extends into the oesophagus and commencement of the small intestines. The mucous membrane is highly inflamed, its vessels are minutely injected with black blood ; see fig. 14, p. 338, in which the black grumous matter and the black injected vessels are shown in a case of poisoning by hydrochloric acid, or the black blood is extravasated into its substance ; the rugae are softened, and extensive destruction of the coats of the stomach, ulcera- tion, and perforation, are of frequent occurrence. The pylorus is com- monly contracted. The duodenum presents similar appearances to those found in the stomach. When perforation takes place, the aper- tures are generally circular, situated at the posterior part of the organ, and surrounded by inflammation and black extravasation. The peri- toneal surface of the viscera, even when there is no perforation of the stomach, is highly inflamed and coated with coagulable lymph. When the contents of the stomach escape into the cavity of the abdomen they act upon the surface of the viscera, and impart to it a peculiar unctuous feel. The inflammation sometimes extends into the chest, so that the thoracic surface of the diaphragm has been found coated with lymph. The blood in the large vessels is often found firmly coagulated. The urinary bladder is generally emjjty and conti-acted. Exceptions to the general rule of the post-mortem appearances are numerous, partly arising from the strength and quantity of the acid, partly from the state of the stomach at the time, and partly from the part of the alimentary canal which the poison reaches. It may not pass beyond the mouth, it may not enter or pass the stomach, or its action may be limited to the upper part of the windpipe. The diagnosis of poisoning by the mineral acids is easy. The imme' diate commencement of the symptoms, the extensive disorganization produced in all the parts with which the acids come in contact, the absence of diarrhoea, the stains on the skin of different parts of the body and on the clothes, form a combination not attributable to any other cause. In the great majority of cases, the symptoms on the 328 MINERAL ACIDS. lx)st-raortem appearances are decisive of themselves, but when com- bined they leave no room for doubt. In almost every instance ad- ditional evidence is afforded by the chemical analysis. Treatment. — The best antidote is calcined magnesia, finely powdered and mixed with water, or milk and water. If this cannot be immedi- ately procured, carbonate of magnesia, chalk, or whiting may be sub- stituted ; and, if these should not happen to be at hand, oil or soap- suds. The plaster from the ceiling or wall of an apartment, beaten into a thin paste with water may be substituted. The pure alkalis and their carbonates, being themselves corrosive poisons, should be given only in weak solution. Previous to the preparation of the anti- dote, and subsequently to it, milk, and mucilaginous and oily drinks should be given frequently and in large quantity, and should be con- tinued for many days. The use of the stomach-pump is contra-indicated in the con-oded and softened state of the parts : indeed, it has often been found impos- sible to introduce it. U the patient is quite unable to swallow, a cautious attempt may be made to int)oduce the tube into the oesophagus beyond the obstruction. The subsequent treatment must depend on the nature and severity of the symptoms. Leeches to the pit of the stomach may be necessary, and sometimes blood will have to be taken from the arm. The bowels must be kept open at first by injections of thin giniel, and as soon as apeiients appear safe, by castor-oil, previously mixed with about twice its quantity of hot milk. Excoriations on the surface must be treated as burns. . 1. SULPHURIC ACID. {Oil of Vitriol.) Sulphuric acid was the cause of death in one-seventeenth of the fatal cases of poisoning in 1837-38. It was the poison administered in 32 out of the 36 cases of poisoning by the mineral acids; of which 32 cases, 21 were accidental, and 7 suicidal, and 4 of a doubtful cha- racter. In the five years 1852-56 it is ci edited with 73 deaths, and it takes the fifth rank among the poisons in order of frequency of use. The strong sulphuric acid is sold by druggists and oilmen as " oil of vitriol" to blacking-makers; and the dilute acid as "vitriol," "spirit of vitriol,'' or "essence of vitriol," for cleaning utensils of copper or brass, at the small charge of Id. for four ounces, or 2d, or Sd. the pound. In medicine, the strong acid is used in the cure of ringworm, and the- dilute acid is often prescribed as an internal remedy. In the arts the acid is largely used for vaiious purposes, and, among othei-s, for the manufacture of other chemicals ; and, as the impure specimens of the acid sometimes contain large quantities of arsenic, that poison is often found in drugs and chemicals as an impurity. SULPHURIC ACID. 329 For medico-legal purposes, we may have to examine, 1. The strong acid. 2: The dilute acid. 3. The acid in stains on cloth, 4. The acid in organic mixtures. 1. Strong Sulphuric Acid. This is an oily liquid, heavier than water, without odoui", not fuming, colourless when pure, but, as found in commei'ce, of a brown tint. It corrodes animal matters, and chars vegetable substances, and when added to water the mixture becomes hot. The charring pro- perty of the acid may be tested by a piece of paper or wood. 2. Dilute Sulphuric Acid. The liquid is known to contain an acid by reddening litmus : it is probable that it contains either free sulphuric acid or free hydrochloric acid, if it chars vegetable matters ;* and it is certain that it does so if, on adding a few drops of nitric acid, and then a solution of nitrate of baryta, a heavj- white precipitate (the sulphate of baryta) falls down. The sulphate of baryta collected, washed, and dried, being mixed with five times its weight of black flux, and heated on charcoal in the reducing flame of the blowpipe, is converted into a sulphide, which, on being placed in a test-tube, and moistened by dilute hydrochloric acid, gives off sulphuretted hydrogen, which may be readily detected by its odour, and by its effect on paper moistened with a solution of acetate of lead, and held over the mouth of the tube. By this three- fold process an acid liquid is proved to contain sulphuric acid ; but not necessarily as free acid. It may be as a constituent of a supersul- phate, such as alum; or the precipitate of sulphate of baryta may have been obtained from a neutral sulpliate, such as Epsom salts, and the acid reaction from some other free acid in excess. The presence of a saline ingredient, or of a neutral salt, will be proved by the result of evaporating the acid liquid ; and the volatile acids, such as the acetic and hydi'ochloric acids, may be separated by distillation, and identified by appropriate tests. 3. Stains on Cloth, The strong acid stains black cloth brown, and corrodes it. The stain continues moist for years, and has an unctuous feel. The dilute acid pi-oduces the same change of colour ; but it is less corrosive, and the spots are diy. * The charring property of sulphuric acid is so remarkable as to constitute a test. If a piece of filtering paper be dipped In a liquid formed by adding a single minim of the strong acid to 800 minims of distilled water, and then dried before a fire without scorching the dry portion of the paper, the part touched by the acid becomes black and brittle. Hydrochloric acid has the same pro- perty, though in a lower degree. 330 MINERAL ACIDS. To detect the acid, the stained fragment of cloth must be digested in a small quantity of warm distilled water for a few horns. The liquid must then be filtered, and treated as dilute sulphuric acid. The acid may be detected after the lapse of several years, Foi- medico- legal purposes, an unstained portion of the same cloth should be exa- mined in the same way. Clean linen and cotton fabrics corroded by the acid may be sub- mitted to destructive distillation in a reduction-tube, over the mouth of which a slip of filtering paper, moistened with a solution of starch, and sprinkled with iodic acid, is held. The sulphurous acid gas combines with the oxygen of the iodic acid, and releases the iodine, which reveals its presence by the bl ue iodide of farina. This process is not appHcable to woollen textures, which contain sulphates, and the results must, in any case, be compared with those of a parallel ex- periment with an unstained portion of the same material. The process is not applicable to the coats of the stomach, or to its contents. 4. Organic Mixtures. Liquids containing organic matter, such as tea and coffee, beer and porter, if thick or tui-bid, must first be boiled with distilled water ; if clear, they may be filtered at once. The coloured precipitate thrown down by nitric acid and nitrate of baryta is to be collected, and boiled in strong nitric acid, to destroy the organic matter, and converted into sulphide of barium, as above. The contents of the stomach, or the matters rejected by vomiting, will have a strong acid reaction if no antidote has been given ; but if the case has received medical treatment, or the patient has survived some time, they may be neutral, or even alkaline. a. If they have an acid reaction, it is probable that they contain a free acid, which may be sulphuric acid, or one of the two acids usually found in the stomach, the acetic and hydrochloric. These acids may be separated by distilling the filtered liquid by the chloride of calcium bath (see hydrochloric acid), till it attains the consistence of a thin syrup. If, on testing the result of the distillation for hydrochloric and acetic acids, neither is present, the liquid in the retort must be diluted, filtered, and tested for sulphuric acid. If, however, the fluid in the leceiver contain either acetic or hydrochloric acid, we dilute the liquid in the retort, and continue the distillation, adding fresh water as often as necessary, till all trace of these acids disappear. The fluid remain- ing in the retort is then to be tested for sulphuric acid. If the fluid has an acid reaction, and also leaves a saline deposit on evaporation ; and the result of distillation proves that the free acid is the sulphuric, we are dealing either with a supersulphate, such as alum, or with a sulphate, such as Epsom salts, in combination with free sulphuric acid. In the latter case, we may want to ascertain the quantity of the uncombined acid, which must be done by adding car- SULPHURIC ACID. 331 bonate of baryta till eflfervescence ceases. The quantity of free acid may be calculated from the weight of the resulting sulphate of baryta. b. If the organic matters have an alkaline reaction, or are neutral, they must be boiled in distilled water and filtered ; the tests being applied to the filtered liquid. If carbonate of lime has been given as an antidote, the resulting sulphate of lime must be dissolved by boiling with nitric acid. When the quantity of acid discovered by any of these processes is very small, there is no proof that it has been swallowed; for the secretions of the stomach always contain a small quantity of neutral sulphates. Nor does the discoveiy of a neutral sulphate, such as the sulphate of magnesia, prove the administration of free sulphuric acid, for the salt itself may have been given as an aperient. The discovery of sulphate of lime, however, by proving the admini- stration of sulphuric acid, and the subsequent use of chalk as an antidote, would be as conclusive as the finding of the free acid. But where the characteristic appearances of poisoning with sul- phuric acid are present, chemical analysis becomes superfluous, except in those rare cases in which the acid is taken in so dilute a form that its more marked post-mortem effects are absent. Sulphuric acid has been detected in parts of the body to which it must have been conveyed by the blood. It has been found in the contents of the peritoneum, pleura, heart, and bladder, and even in the liquor amnii, and body of the foetus. (' Med. Gaz.,' vol. i., p. 710.) The milk of nurses who were taking the acid has been found to produce disordered bowels and convulsions in children whom they were suckling ; and in one case (* Med. Gaz.,' vol. i., p. 756) the matters voided from the bowels of the child were found to corrode the napkin. Quantitative Analysis. — Use for this purpose the precipitated sul- phate of baryta, previously boiled in pure nitric acid, and then care- fully washed and dried. In 100 grains of the sulphate there are 41 ^ grains of the strong acid, SYMPTOMS, POST-MORTEM APPEARANCES, AND TREATMENT. Symptoms. — Those already described at p. 325 , but severe in pro- portion to the strength and corrosive properties of the acid. Seveie nervous symptoms are sometimes present, such as locked-jaw, rigid spasms of the extremities, epilepsy, and delirium. Diagnosis. — The dark-brown stains on the skin, and the moist bi'own corroded stains on black cloth, are characteristic of this acid. Post-mortem Appearances. — Those described at p. 327 ; but the degree of disorganization greater, and perforation more frequent (about two-thirds of the cases), than in poisoning by the other mineral acids. The colour of the epithelium and mucous membrane dark-brown or black, as if charred; while in cases of poisoning by nitric acid it is 332 MINERAL ACIDS. more commonly yellow or green. When thickly coated with mucus, the lining membrane of the mouth and of the sevei-al portions of the alimentary canal acted on by the acid, has the appearance of being coated with white paint. Dr. Chowne has shown that this is the effect of sulphuric acid on the secretions of the alimentary canal after death. On the mucous membrane itself after death, the local eil'ect of the acid, as shown by Orfila, is to render the membrane yellowish and brittle, to bleach the muscular and peritoneal coat, and to char the blood in the vessels. Smallest fatal dose. — In the adult, one drachm. A less quantity in the infant. In one instance, half a teaspoonful of the dilute acid proved fatal to an infant five weeks old. (' Med. Gaz.,' vol. xxii., p. 389.) Two ounces have been swallowed by adults without fatal conse- quences. Shortest fatal period. — Two hours. In fatal cases, life may be prolonged for several days, weeks, or even months. Average Duration. — In cases which prove fatal within 24 hours, about 10 hours. Mortality. — Almost all infants and young children. In adults, two-thirds of the cases.* Treatment. — That already described at p. 328. * The following are the general results of several cases reported in the English and Foreign Journals : — Of 36 cases (of which the majority occurred in females) — 26 were fatal (all the children and 18 adults), and 10 recovered (all adults). Of 31 cases — 20 were suicidal, 3 homicidal (all young children), and 8 acci- dental (2 of them children). Among adults, the recoveries were to the deaths, both in accidental and suicidal poisoning, as 1 to 2. Of the 26 fatal cases, 10 lasted a day or less ; 6 more than a day and less than a week ; 3 less than a fortnight ; 1 from a fortnight to three weeks ; 1 more than three weeks ; and 5 extended from live to forty-five weeks. The following were the precise periods of death — in 5 children, 1 in 3i hours, 2 in 4i hours, 1 in 12 hours, and 1 in 3 days." In 20 adults— 1 in 3i hours, ] in about 4 hours, 1 in 8 hours, and 1 in 12 hours; 2 in 1 day, 1 in 1^ day, 2 in 2 days, 1 in 4 days, 1 in 5 days, 1 in 8 days, 1 in 11, 15, 22, and 33 days respec- tively, and 2 in 60 days: 1 in 26 weeks, and 1 in 45 weeks. The average duration in all who survived a day or less was 10 hours— of all surviving a week or less 32 hours. The recoveries are stated to have taken place in 6, 7, 10, 11, 14, 18, and 23 days respectively. Perforation of the stomach took place in 8 cases out of 21 in which the post- mortem appearances are described. The reader is referred to the following cases reported in English Journals, or extracted from foreign publications : — Ed. Med. and Surg. Journal— "Vol. x. p. 527. Vol. xxii. Vol. xxvi. Vol. xxxvi. p. 99. Vol. liii. p. 406 et seq. (an interesting case by Dr. Craigie with many valuable cases from foreign sources), and Vol. Ivi. p. 537. — Lancet, 1834-5, 1. p. 266. 1836—7, i. p. 195. 1837—8, 11. p. 782.— Medical Gazette, Vol. i. p. 127. Vol. vii. p. 27. Vol. xxii. p. 76. Vol. xxv. p. 944. Vol. xxix. p. 147. Vol. XXX. p. 352, — Medical and Physical Journal, Vol. i. p. 500.— Medical Repositorj", Vol. xiv. p. ] 60.— Guy's Hospital Reports, Vol. iv. p. 297.— See also Dr. Roupell's Illustrations of the effects of poisons. NITKIC ACID. 333 Sulphuric acid has been introduced into the body in other ways than by the mouth. It has been injected into the vagina to procure abortion ; and into the rectum by mistake for a clyster ; and it is sometimes used to disfigure the face and injure the dress. The local treatment of parts thus injured will consist in the use of alkaline lotions to neutralize the acid, followed by that appropriate to burns. 2. NITKIC ACID. {Aqua Fortis, Eed Spirit of Nitre.) This acid is much less frequently used as a poison than sulphuric acid, but moi'e frequently than hydrochloric acid. It was the cause of four deaths in. 1837-38, two of which were from the unmixed acid; and of two deaths only in the five years 1852-56. The poison may present itself for analysis, 1, as the strong acid ; 2, as the dilute acid ; 3, in stains on cloth ; and, 4, in organic mixtures. 1. Strong Nitric Acid. This acid, as met with in commerce, varies in colour from a deep orange to a light yellow ; gives out orange-coloured acid fumes ; pro- duces dry yellow stains in black cloth, which it also coiTodes, though in a less degree than sulphuric acid, and causes similar stains in other articles of dress, and in the skin and other tissues of the body. These stains become brighter when touched with an alkali. When poured on coj^per, tin, lead, or mercury, ruddy, colourless fumes of binoxide of nitrogen are given off, which immediately become ruddy on admixture with air, a brisk effervescence takes place, and a greenish liquid remains. With morphia and its salts, the acid strikes a rich orange colour. 2. Dilute Nitric Acid. The liquid is proved to contain an acid by the effect on litmus paper. The addition of a few drops of pure nitric acid and nitrate of baryta, by the absence of precipitate, proves that sulphuric acid is not present. The absence of precipitate on adding a solution of nitrate of silver shows that it is not hydrochloric acid. If a mineral acid, therefore, it is nitric acid ; and as most of the vegetable acids give a precipitate with nitrate of silver, there is a strong presumption in favour of the liquid containing nitric acid. This presumption is con- verted into certainty by the following tests : — a. When boiled with copper filings, provided the acid be not very dilute, the characteristic orange fumes are given off. b. It' carbonate of potash is added to the liquid till effervescence ceases, and a piece of filtering paper is dipped into the liquid and dried, it burns like touch-paper, c. On slowly evapoi'ating the liquid, it yields crystals of nitrate of potash. The crystals of nitrate of potash obtained in this manner fromvthe solution, yield further corroborative proofs of the nature of the acid, by the following reactions: — a. The crystals are lengthened, fluted prisms, permanent in the air. b. When ignited on charcoal, they burn 334 MINERAL ACIDS. with deflagration, c. On the addition of strong sulphuric acid, a colourless vapour with the peculiar odour of nitric acid is given off'. (/. Place a fragment of the salt on a por<;elain slab, add one or two •Irops of distilled water, and then a drop of strong sulphuric acid ; in the resulting liquid place a fragment of morphia. The morphia will assume a rich orange colour, and gradually impart to the liquid a deep yellow tint. e. Substitute for the morphia a fragment of copper : the ruddy fumes of nitrous acid will be given off. /. Place on a porcelain slab a crystal of the salt, moisten it with distilled water, add a drop of concentrated sulphuric acid, apply the heat of a spirit lamp, and, as effervescence takes place, introduce into the liquid a crystal of the green sulphate of iron ; a dark green ring, changing to brown, will form round the crystal, g. Place a crystal of nitre on a porcelain slab, moisten with distilled water, add a drop of strong sulphuric acid, and one or two drops of strong hydrochloric acid : the resulting liquid dissolves gold leaf. 3. Stains on Cloth. Strong nitric acid injures the texture of black cloth, and produces a dry stain, which is at first yellow, or orange, but grows darker by the lapse of time. It is deepened in colour when touched by an alkali. The process of analysis is very simple. The fragment of cloth must be digested in a small quantity of warm distilled water. The presence of an acid will be indicated by test paper ; and the nature of the acid will be inferred from the appearance of the stain. The acid is then to be neutralized with carbonate of potash, and the solution filtered. The dry filter will burn like touch-paper. Evaporate the liquid, collect the crystals, and apply the morphia test on a surface of white porcelain ; and if possible apply the other tests in succession. As nitric acid is less permanent than sulphuric acid, it cannot be detected in stains on cloth after so long a period. But Dr. O'Shaughnessy obtained satisfactoiy evidence of its presence in a fragment of cloth from a coat which had been folded up " during the previous summer ntionths." — ('Lancet,' August 1830.) It may be necessary to distinguish stains produced by nitric acid from those caused by iodine or by bile. The stains from nitric acid are indelible, and when touched with a weak solution of caustic potash become orange yellow. Those caused by iodine immediately disappear ; the bile-stain undergoes no change. (Barruel.) 4. Organic Mixtures. If the liquid is viscid, dilute with distilled water, boil, and filter. If it has an acid reaction, neutralize with carbonate of potash, crys- tallize, and apply the tests already described. If antidotes, such as chalk or magnesia, have been given, the liquid, instead of having an acid reaction, may be neutral or feebly alkaline NITRIC ACID. 335 In this case, also, the filtered liquid is to be neutralized with carbonate of potash ; soluble nitrate of potash will be formed, and insoluble carbonate of lime or magnesia will be thrown down, which must be separated by fresh filtration. The filtered liquid is then to be evapo- rated, and the crystalline residue tested for nitrate of potash. When the quantity of acid in the organic liquid is very small, it has been recommended to filter the liquid from the vessel containing it by means of a rough syphon formed of filtering paper. (Christison.) Portions of mucous membrane acted upon by the acid may be treated in the same manner as fragments of cloth. In the case of nitric as of sulphuric acid, the post-mortem appear- ances are so characteristic as to render chemical analysis unnecessary. Quantitative analysis. — To the nitrate of potash add strong sul- phuric acid ; dissolve the sulphate, calcine it, wash with alcohol to remove free sulphuric acid, and evaporate to dryness. For one hun- dred grains of the dry sulphate allow about eighty-two grains of liquid nitric acid. SYMPTOMS, POST-MORTEM APPEARANCES, AND TREATMENT. Si/mptoms. — Those already described (p. 325). A miliary rash, attended with intolerable itching, was present in one case on the sixth day. Diagnosis. — The yellow stains on the skin, and the dry yellow corrosions on the dress, are characteristic of this acid ; and the dis- covery of these stains on the person and dress has often led to detection in homicidal cases. Post-mortem appearances.' — Those already described (p. 327). The colour of the mucous membrane yellow or green in parts of the stomach and intestines containing bile. The degree of corrosion less, and perforation of rarer occurrence, than in poisoning with sulphuric acid. Smallest fatal dose. — Two drachms. (Taylor.) In infants less. Recovery has taken place after half an ounce, or more. The shoi^test fatal period. — In the adult one hour and three quar- ters : in the infant a few minutes. Average duration. — In the majority of fatal cases death takes place within twenty-four hours ; but hfe may be prolonged to several days, weeks, or months. Treatment. — That pi'escribed for tlie mineral acids generally (p. 328). Nitric acid has been introduced into the body in other ways than by the mouth. In one case it was poured into the ear, and caused in succession sloughing, abundant haemorrhage, paralysis jactitans, ex- treme debility, and death in about thirteen weeks. (* Med. Gaz.' March, 1830.) The orange fumes given off when nitric acid is poured upon copper or mercury (and which are commonly known as nitrous acid gas) are 336 MINERAL ACIDS. produced in large quantity in some processes of the arts, such as water- gilding and brass-button making. They irritate the eyes and lungs, and give rise to a troublesome cough renewed by each repetition of the pro- cess ; and at length becoming habitual. In more than one instance it has proved fatal in periods vaiying from twenty-seven hours to two days. The sipnptoms are a burning heat in the throat; tightness at the chest and pit of the stomach ; extreme distension and acute pain of the abdomen ; nausea and vomiting ; purging of a yellow matter ; scanty secretion of urine and dysuria ; a cough at first dry, and then attended by scanty orange expectoration, with extreme dyspnoea, and feeling of impending suffocation ; transient delirium ; extreme debility ; and inexpressible anxiety; and death after convuiaions. The post- mortem appearances consist in signs of acute inflammation and its consequences in the air-passages and lungs, and in the alimentary canal, engorgement of the lungs and heart with black liquid blood, distension of the stomach and intestines with gas, and a yellow colour of the contents of the air-passages and alimentaiy canal. Manufac- turers who produce these irritating fumes ought to be required to conduct them into the nearest chimney. The binoxide or deutoxide of nitrogen which, when mixed with air, gives lise to these orange fumes, cannot be respired without producing them by combining with the atmospheric air in the lungs. Hence it cannot excite surprise that Sir H. Davy suffered very severely when he tried to inhale the binoxide. 3. MURIATIC ACID. {Ili/drochlortc acid. Spirit of Salt.) Though muriatic acid is somewhat largely employed in the art^, it is not often used as a poison. No case of poisoning by it was leported in the years 1837-38; only two cases in the five years 1852-56, and less than half a dozen cases have occurred since that time. The poison may have to be examined, 1. As the strong acid. 2. As the diluted acid. 3. In stains on cloth. 4. In organic mixtures. 1. Strong Muriatic Acid. The acid of commerce is of a yellow colour, fuming when highly concentrated, and yielding dense white fumes with the vapour of ammonia. It produces a green stain in black cloth, but does not corrode it ; or the stain is first red and then green ; and it reddens vegetable blues. It is distinguished from sulphuric acid by its colour, and from nitric acid by the absence of orange fumes when poured on metals. When boiled with black oxide of manganese, chlorine is given off, which is known by its colour, odour, and bleaching properties, 2. Dilute Muriatic Acid. Having ascertained that the liquid contains an acid by the use of litmus paper, we first test it by nitric acid and nitrate of baryta ; MURIATIC ACID. 337 if there is no precipitate it is probable that the acid is either nitric or muriatic. If on testing it with a solution of nitrate of silver we obtain a dense white precipitate, the probability is greatly strengthened ; and if the precipitate is insoluble in nitric acid, and in caustic potash, but very soluble in ammonia, and, when dried and heated fuses into a horny mass, which may be cut with a knife, the acid is certainly mm-iatic acid. As a chloride (such as common salt) with a free acid would have an acid reaction, and yield the same white precipitate with nitrate of silver, a portion of the liquid should be evaporated, when, if there is a crystalline residue, the acids should be distilled over and the crystal- line residue examined. 3. Stains on Cloth. Digest the stained cloth in warm distilled water, filter, test with nitrate of silver, and identify the precipitate as above. Examine, at the same time, an unstained portion of the same cloth. 4, Organic Mixtures. Most organic liquids contain muriatic acid free or combined, and most organic matters yield a precipitate with nitrate of silver. In the contents of the stomach, the acid may either exist in the free state, in which case the liquid will have a strong acid reaction, or it may be combined with an antidote, in which case the liquid may be neutral. If the liquid has a strong acid reaction, we submit it to distillation at a low temperature, by immersing the retort in a boiling solution of chloride of calcium (two parts of the salt to one of water), the distil- lation being repeated by adding distilled water to the dry residue. The liquid in the receiver may be ti-eated as pure diluted acid. If by this means we detect free muriatic acid in the contents of the stomach only in minute quantity, the proof of poisoning by this acid will be incomplete, for the gastric juice itself contains a minute pro- portion (one part in 1500) of free muriatic acid. But when the acid is found in considerable quantity in the stomach of a person in whom the symptoms during life and the post-mortem appearances were those due to the action of a mineral acid, the cause of death will be clearly proved. If the organic liquid is neutral, it may either contain no muriatic acid, or the acid may be combined with an antidote — magnesia, lime, soda, or potash. In this case we evaporate to dryness and calcine, dissolve the residue, and test the solution with nitrate of silver. If the residue consists of common salt, it may have resulted from the administration of carbonate of soda as an antidote, or the common salt may have formed a part of the food. Here, again, the result of the chemical analysis is worthless unless supported by the symptoms and post-mortem appearances, and the stains which we may discover on the clothes. z 338 MINERAL ACIDS. Quantitative Analysis. — Use for this purpose the dried precipitated chloride of silver, of which 100 grains are equivalent to 69 grains of liquid muriatic acid. Symptoms. — Those already described (p. 325). Post-mortem Appearances. — Those already described (p. 327). In a suicidal case, in which a large quantity of the strong acid was taken, and proved fatal in less than twenty-four hours, the epithelium of the throat and gullet was destroyed in patches, and the stomach contained a large quantity of black grumous matter, adhering to the surface so as to admit of being preserved. The preparation, with a drawing from the recent gullet and stomach, is in the Museum at King's College. As the appearances in this case, especially^he shrivelled and worm-eaten aspect of the gullet, bear a very near resemblance to those present in cases of poisoning by sulphuric acid (see Roupell's Plates) and to one case of poisoning by oxalic acid which came under my notice, I append three woodcuts which, even in the absence of colours, convey a very clear idea of the actual appearances. Fig. 12 shows the corrugated and worm-eaten appearance of the gullet ; fig. 13 a portion of the gullet from which a large patch of epithelium has been removed, and fig. 14 the appearance of the stomach with its black grumous contents and the vessels injected with black blood. The preparation was pre- sented to the Museum by Mr. Bowman FiR. 14. Fig. 12. FiK. 13. The mucous membrane of the stomach and intestines sometimes has a yellow tint, or it is green from the action of the acid on the bile. No case of perforation has yet been reported ; but in a case of poisoning by a large dose of the dilute acid reported by Puchelt of Heidelberg, the entire stomach is stated to have been destroyed, and rejected by vomiting. Smallest fatal dose. — One ounce. Shortest fatal period. — Five hours and a half. Average period. — About twenty-four hours. Treatment. — That of poisoning by the other mineral acids (p. 328). MIXED ACIDS USED IN THE ARTS. 339 Nitric acid mixed with sulphuric, under the name of aqua regince, and with muriatic acid, under the title of aqua regia, are used in the aits, the one to separate silver from plated articles and in the manu- facture of collodion, the other to dissolve gold and platinum. The mineral acids have also been taken in a state of mixture with other substances — nitric acid with laudanum, aloes, &c. ; and muriatic acid, in combination with tincture of iron and corrosive sublimate, is in common use for browning gun-bai-rels, and has been taken as a poison in one case (' Medical Gazette,' November, 1839). 340 CHAPTER IV. THE ALKALIS AND THEIR CARBONATES. 1. Potash and Carbonate of Potash. 2. Soda and Carbonate of Soda. 3. Ammonia and Carbonate of Amm^ia. The alkalis and their carbonates share with the preceding sub-class of initants, the mineral acids, the property of destroying the animal tissues by the violence of their action, at the same time that they give rise to no specific or peculiar remote efiiects. The corrosive property of these poisons belongs to them only when swallowed in substance, or in strong solution, as that of the mineral acids belongs to the concen- trated acids or their less dilute mixtures. The alkalis and their carbonates, in common with the alkaline earths, are distinguished from one class of the metals, commonly so called, by the negative eflect of sulphide of ammonium, from another class by the negative effect both of hydro-sulphuric acid and sulphide of ammonium. They resemble the alkaline earths in having an alka- line reaction ; but they differ from them by yielding no precipitate with carbonate of ammonia. Though the alkalis and their carbonates are in very common use for household purposes, or as medicines, they are very rarely administered, or taken by accident, as poisons. 1. POTASH AND CARBONATE OF POTASH. Caustic Potash, as used in the laboratory, is in the form of greyish masses, which present when broken an imperfect crystalline texture, are soapy to the touch, acrid to the taste, highly deliquescent, fusible by heat, rapidly absorbing carbonic acid from the air, and very soluble in water. When fused in small cylindrical ^moulds it is the potassa fusa of the shops. In solution (the liquor potassce of the shops and laboratory) it has a strong alkaline reaction ; changes the colour of black cloth to brown ; is not precipitated by carbonic or sulphuric acid, but yields with a solution of bichloride of platinum a yellow precipitate. The carbonate of potash, bicarbonate of potash, or salt of tartar, is sold by oilmen in two forms. 1. As a mottled deliquescent mass — yellow, grey, brown, and black — with a soapy feel, a urinous taste, and a strong alkaline reaction. In this form it is known as Potash or POTASH AND CARBONATE OF POTASH. 341 Potashes, and is used chiefly for cleaning oil lamps. 2. In small white grains, or as a white semi-crystalline mass, having similar de- tergent properties, and used for washing and other cleansing purposes. In this form it is known as Pearlash. We may have to examine and identify these salts. 1, In substance. 2. In solution. 3. In organic mixtures. 1. In Substance. Potash (or potashes) is readily recognized by the physical properties just described. The more pure form of carbonate of potash requires to be distinguished from carbonate of soda, and from other white powders. It has an alkaline reaction, effervesces and gives out carbonic acid when treated by acids, and imparts a violet tint to the deoxidizing flame of the blowpipe. It is very soluble, and has in a state of solution the properties now to be described. 2. In Solution. A solution of carbonate of potash when evaporated on platinum foil leaves a white deposit not dissipated by heat, and is thus distin- guished from the salts of ammonia : it has an alkaline reaction ; it yields a yellow precipitate with a solution of bichloride of platinum, in which respect it resembles the salts of ammonia, but differs from those of soda ; it gives a colourless precipitate of bitartrate of potash with a solution of tartaric acid, which precipitate is promoted by agitation and by friction with a glass rod. 3. In Organic Mixtures. If an organic liquid has a strong alkaline reaction, there is a pre- sumption in favour of one of the substances contained in this chapter. By diluting and filtering a small portion of the liquid, and applying trial tests, it will be easy to ascertain which of the three alkalis is present. The process for the carbonate of potash consists in evaporating the organic matter to dryness, incinerating the residue, treating the ash with distilled water, and applying to the solution the tests just enumerated. SVMPTOMS, POST-MORTEM APPEARANCES, AND TREATMENT. Symptoms. — When a strong solution of the poison is taken, an acrid burning taste is perceived in the act of swallowing, followed imin> diately by a burning sensation in the throat and gullet. This is soon followed by acute pain in the pit of the stomach, with great tenderness on pressure; frequent and violent vomiting of a tenacious bloody mucus, of a brown grumous matter, or of flakes of epithelium. Violent colic pains, with tension and tenderness of the abdomen, soon supervene, and there is purging of stringy mucus mixed with blood. 342 THE ALKALIS AND THEIU CARBONATES. Theie is much difficulty in swallowing, and sometimes hoai-seness of the voice, and cough. In fatal cases, death either takes place with symptoms of collapse, or after prolonged sufferings from increasing difficulty in swallowing, constant vomiting of blood, bloody stools, and tenesmus. In chronic cases the patient dies from starvation, through the long-continued stricture of the oesophagus. Post-mortem Appearances. — The lining membrane of the throat and gullet is softened and corroded ; the oesophagus, stomach, and intestines are inflamed, with abrasion and ulceration of the lining membrane, and dark spots or patches caused by the extravasation of blood. Sometimes the inflammation extends to the larynx. In chronic cases, large portions of epithelium and mucous membrane are found removed, and the gullet and stomach are contracted. Perforation has not taken place in any of the recorded cases. Smallest fatal quantity. — Half an ounce. Shortest Jatal period. — Three hours. Average fatal period.— In the majority of fatal cases death takes place within twenty-four hours. In chronic cases, the fatal event may be delayed for days, weeks, months, or tven years. Treatment. — As an antidote, vinegar largely diluted with water or lemon-juice and water. Acidulated demulcent drinks, and the juice of oranges and ripe fruits may then be freely administered, and almond or olive oil. Inflammatory symptoms must be combated with anti- phlogistics, pain by preparations of opium, and collapse, if present, by the usual stimulants. The stomach-pump should not be used. 2. SODA AND CARBONATE OF SODA. Caustic soda has no medico-legal interestj Carbonate of soda is sold by oilmen for cleansing purposes, in two forms, as soda and best soda — the soda in a dirty crystalline mass, the best soda in masses of a purer white. In common with potash, carbonate of soda may have to be identified in substance, in solution, and in organic mixtures. 1. In Substance. Carbonate of soda has an alkaline reaction ; it efiervesces and gives oqt carbonic acid when treated with an acid ; it readily crystallizes, and is efflorescent, and it imparts a yellow colour to the flame of the blowpipe. 2. In Solution. A solution of carbonate of soda dilTere from a solution of carbonate f>f potash by yielding no precipitate with the bichloride of platinum, or with tartaric acid ; while it gives with antimoniate of potash a white ciystalliue precipitate. Further distinctions might, if necessary, be founded on the form and character of the salts of the two alkalis ; but this is unnecessary. It will suffice to state that when converted into AMMONIA AND CARBONATE OF AMMONIA, 343 nitrates by adding dilute nitric acid, soda crystallizes as rhombic plates, and potash as prisms. 3. In Organic Mixtures. The process for organic liquids containing carbonate of soda is the same as for those containing carbonate of potash. SYMPTOMS, POST-MORTEM APPEARANCES, AND TREATMENT. Symptoms. — Those of poisoning by carbonate of potash, but of less severity. Post-mortem Appearances. — Those of poisoning by carbonate of potash, though less marked. Treatment. — That of poisoning by carbonate of potash. 3. AMMONIA AND CARBONATE OF AMMONIA. Ammonia in the form of gas, or dissolved in water, as the liquor ammonicB, or in combination with carbonic acid gas as the sesqui- carbonate of ammonia, is largely used in medicine and the arts, and is occasionally taken as a poison, generally by accident; but in rare instances it is taken or given v/ith intent to destroy life. The in- cautious use of the vapour of ammonia with a view to rouse patients from syncope, or asphyxia, or as an antidote to prussic acid, has also caused death by suffocation or inflammation of the air-passages. The vapour of ammonia is readily recognized by its pungent odour, and it is distinguished from the tixed alkalis by the change produced in vegetable colours being dissipated by heat. The sesquicarbonate (vulgarly known as hartshorn, volatile salt, or smelling salts) is recog- nized by its pungent odour, and distinguished from the carbonates of potash and soda by being completely dissipated when heated on pla- tinum foil. It is distinguished from liquid ammonia by effervescing with an acid, and yielding a white precipitate with the salts of lime. Ammonia is set free from its salts when they are heated with liquor potasssp in a test tube, the vapour of ammonia being identified by the odour, by its alkaline leaction on turmei'ic or reddened litmus paper, and by the dense fumes formed when brought into contact with hydro- chloric acid. Ammonia in organic mixtures must first be separated by distillation and then identified by its appiopriate tests. Symptoms. — These, as far as they are due to actual contact, are the same as those produced by potash and soda, and their carbonates ; but from its extreme volatility it gains access to the air-passages, and has thus proved fatal in so short a time as four minutes. Post-mortem Appearances. — Signs of violent inflammation in the alimentary canal with separation of the epithelium of the mouth, and inflammatory appearances in the air-passages. Trratment. — Vinegar and water as an antidote, and the after-treat- ment proper to the class of irritants. 344 CHAPTER V. THE VEGETABLE ACIDS. 1. Oxalic Acid (and the Binoxalate of Potash). 2. Tartaric Acid (and Bi tartrate of Potash). 1. OXALIC ACID {Acid of Sugar). This substance is largely used in the arts, under the common name of acid of sugar. It is in use among bookbinders, shoemakers, and workers in leather, among straw-bonnet makers and workers in straw ; and among workers in brass. It is also commonly employed to take ink-stains out of linen. It is sold both by druggists and by persons who supply the trades using it. Its cheapness (2d. per ounce), common employment, and known activity, commend it to the suicide ; its resemblance to Epsom salts leads to accidents ; while its strong acid taste unfits it for the purpose of the murderer, unless mixed with some strongly-flavoured liquoi', such as gin, brandy, or rum, or strong tea or coffee. Oxalic acid, for the reasons stated, is in common use as a poison, taking the sixth place among the ascertained poisons. In the five years, 1852-56, it was credited with 13 deaths per annum, or about 1 in 21 of the ascertained poisons. Of these 13 deaths, 4 occurred in men and 9 in women, and 10 of the 13 were suicidal cases. Of the 19 cases traced to oxalic acid in the two years, 1837-8, 13 were suicidal and 1 accidental ; while of 15 cases which I have collected from 'different sources, 8 were suicidal, 5 accidental, and 2 unascer- tained. Of the 15 cases 12 occurred in women and only 3 in men. Tests.— OxbWc acid may have to be examined in substance, in solu- tion, and in organic mixtures. 1. In- Substance. The crystals are transparent, colourless or nearly so, permanent in the air (unless containing nitric acid), very sour to the taste, soluble in about their own weight of hot water, and in from eight to twelve or fourteen times their weight of cold water. They are also soluble in alcohol. The crystals are four-sided prisms, with dihedral or tetrahedral summits ; and they bear such a resemblance to the crystals of sulphate of magnesia and sulphate of zinc, as to be occasionally confounded with them. The distinction, howerer, is easy. Oxalic acid has an intensely OXALIC ACID. 345 sour taste ; the other salts are bitter : the solution of oxalic acid has a strong acid reaction ; that of the sulphate of magnesia is neutral, and of the sulphate of zinc only slightly acid : oxalic acid is entirely dissi- dated by heat, or, if impure, leaves only a scanty saline residue ; the sulphates of magnesia and zinc are fixed : liquor potassaj added to a solution of oxalic acid produces no change ; but it precipitates the white oxides of the sulphates of magnesia and zinc ; oxalic acid effer- vesces with solutions of the alkaline carbonates, but yields no precipi- tate, while the sulphates of zinc and magnesia give a white precipitate, without effervescence. Oxalic acid discharges the colour of ink ; the other crystals produce no change in it.. Oxalic acid is sufficiently dis- tinguished from the citric and tartaric acids by the defined shape of its crystals. 2. In Solution. The liquid is known to contain an acid by its action on litmus, and a vegetable acid or acid salt if it yields crystals on evaporation. Long slender prismatic crystals, dissipated by heat, afford a strong pro- bability of the presence of oxalic acid. On the supposition that we are ignorant of the nature of the acid, we acidulate with a few drops of nitric acid and then add a solution of nitrate of baryta. The absence of precipitate shows that it is not sulphuric acid. We then add to another portion of the liquid a i%v{ drops of a solution of nitrate of silver ; a white precipitate is thrown down, which will be identified as oxalate of silver by the tests presently to be described. If we have reason to believe that the acid liquor contains oxalic acid, we may obtain more complete evidence by evaporating and obtaining crystals, or by the addition of ammonia, which, if the solution contain a large proportion of the acid, will produce a characteristic radiated crystallization of oxalate of ammonia. The characteristic tests by which the oxalic acid may be fully identified are the following : 1. Nitrate of Silver. — It throws down an abundant white precipitate of oxalate of silver, soluble in nitric acid and ammonia ; and which, when dried and heated on platinum foil, detonates, and is dispersed as a white vapour, leaving a residue of metallic silver. 2. Sulphate of Lime. — The salts of lime give with oxalic acid a white precipitate, the oxalate of lime, soluble in nitric and hydro- chloric acids, but insoluble in the vegetable acids. The solution of the sulphate of lime should be added in large quantity. A solution of sulphate of copper is often mentioned as a test for oxalic acid. It throws down a greenish-white precipitate of oxalate of copper. The soluble salts of lead also give a white precipitate — a fact of which we avail ourselves in the process for organic liquids. 3. In Organic Liquids. As oxalic acid is not altered by contact with the animal textures or with food, and it is not often that an antidote can be given, the process for the free acid is comparatively simple. 346 THE VEGETABLE ACIDS. The acid liquid if dilate may be filtered at once, but if not, we add distilled water, allow the liquid to stand for a time, filter it, and con- centrate by evaporation. To the resulting liquid we add acetate of lead till a precipitate ceases to be formed. This precipitate, the oxalate of lead, is then diffused through distilled water, and sulphuretted hy- drogen gas transmitted for two hours through the mixture. Black sulphuret of lead is thrown down, and oxalic acid is set free. The sulphuret having been separated by filtration, the oxalic acid remains in solution, and may be identified by the tests just described. If carbonate of lime or of magnesia had been employed as an anti- dote, we shall have to adopt a modified process by which the acid may be detached from the base. The fragments of solid matter must first be rubbed down, and the mixture must then be brought to the con- sistence of a thin syrup by the addition, if necessary, of distilled water. To this about a twentieth part of its bulk of cai'bonate of potash must be a dded, and it must then be boiled for two hours. The resulting liquid will contain soluble oxalate of potash, and insoluble carbonate of lime or of magnesia. The insoluble matters being now separated by filtration, the liquid which passes the filter will consist of oxalate of potash in solution. The alkali is now to be neutralized with pure nitric acid, and the solution of acetate of lead is to be added as long as any precipitate falls. Collect, as before, the oxalate of lead, suspend it in distilled water, separate the oxalic acid by sulphuretted hydrogen gas, and identify the oxalic acid by the tests already described. If the antidotes which have been administered have only partially neutralized the oxalic acid, and the sepai-ated liquid has an acid reac- tion, the process first described must be adopted for the liquid portion, and the second process for the solid matters. As oxalate of lime exists in large proportion, but in small absolute quantity in rhubarb, it is always possible to attribute its detection, when in small quantity, to rhubarb taken medicinally. The history of the case, with the previous symptoms and post-mortem appearances, will at once destroy this objection. A strong solution of oxalic acid stains black cloth of a deep-biown colour without corroding it, and reddens the vegetable blues. In consequence of its lemoving the colour of ink, it has been used to discharge writing. Quantitative Analysis. — Use for this purpose the oxalate of lead. Every hundred grains correspond to forty-two of the crystallized acid. Experiments on Animals. — Large doses (such as ^ss.) in strong solution cause symptoms of irritant poisoning, and death from collapse in fi'om two to twenty minutes. Alter death, black extravasated blood is found in the stomach,»and there are marks of acute inflammation, with hardening or softening of the lining membrane. The diluted acid in large doses kills by paralyzing the heart ; in lesser doses by tetanic spasm of the muscles of respiration, and in still smaller ones by coma. OXALIC ACID. 347 SYMPTOMS, POST-MORTEM APPEARANCES, AND TREATMENT. Symptoms. — The symptoms in man vary with the dose and the degree of concentration of the poison. When the dose is large, and the solution concentrated, the symptoms follow immediately on the swallowing of the poison. An intensely sour taste is speedily followed by a burning sensation in the pit of the stomach, increased by pressure, and pain and constriction of the throat. The pain is soon succeeded by vomiting, sometimes of blood, but generally of a greenish-brown or black grumous matter. If the patient survive several hours, there is purging of a similar matter, sometimes tinged with blood. The re- maining symptoms are those of collapse, — extreme debility, pale and anxious countenance, cold and clammy sliin, small and frequent pulse, and hurried respiration. There are also soreness of the mouth, inflam- mation and swelling of the tongue, constriction of the throat, painful deglutition, intense thirst, restlessness, difficulty of breathing, and harassing cough. Cramps and numbness of the legs and arms, acute pain in the head and back, delirium and convulsions, are among the nervous symptoms present in certain cases. These symptoms are subject to many anomalies and exceptions. Even pain and vomiting have been altogether absent, or vomiting did not occur till emetics were administered. An eruption has in one case appeared on the skin. From the speedy death of leeches applied to the epigastrium in a case of poisoning by oxalic acid, it is inferred that the blood is poisoned. Fost-mo7'tem Appearances. — The external appearance of the body is natural, and the countenance pale and composed. The lining mem- brane of the mouth and fauces is generally white, shrivelled, and easily detached ; and a similar appearance extends into the gullet, which is contracted into folds both longitudinally and transversely, while the epithelium is detached in small in-egular patches, leaving a brown surface beneath. The tube sometimes closely resembles a piece of worm-eaten wood. (See figures 12 and 13, p. 338.) The stomach contains a dark-brown, or greenish-brown, grumous matter, in appear- ance nearly resembling meconium, which also lines the oesophagus, and extends into the duodenum. The mucous membrane is sometimes quite pale, and free from rugae ; at others, the membrane is highly inflamed, and the rugae strongly marked. It is easily stripped off, and in some instances has been extensively detached. Its vessels are mi- nutely injected with black blood. (See fig. 14, p. 338.) Perforation is rare. In eases of some continuance, the small intestines present the same appearances as the stomach. The peritoneum has been found inflamed, and in one case the right pleura. The lungs are sometimes greatly congested, and in one instance there were some traces of inflam- mation in the brain. In rare instances, the most charactei'istic post-mortem appearances, like the symptoms during life, are absent. 348 THE VEGETABLE ACIDS. As a general rule it may be stated that both the symptoms and post-mortem appearances, in poisoning by oxalic acid, are highly cha- racteristic. Christisou justly observes, " If a person, immediately after swallowing a solution of a crystalline salt, which tasted purely and strongly acid, is attacked with burning in the throat, then with burning in the stomach, vomiting, particularly of bloody matter, im- perceptible pulse, and excessive languor, and dies in half an hour, or, still more, in twenty, fifteen, or ten minutes, I do not know any fallacy which can interfere with the conclusion, that oxalic acid was the cause of death. No parallel disease begins so abruptly, and ter- minates so soon ; and no other crystalline poison has the same eftects."* It may be added, that the post-mortem appearances, though not equally characteristic, afford a strong probability. The wrinkled and corroded gullet, the pale, shrivelled, and partially-detached mucous membrane of the stomach, the dark veins ramifying on its surface, and the dark-brown grumous matter which fills its cavity, point strongly to the action of a powerful corrosive poison, while the absence of the coloured spots on the skin would preclude the supposition of the etfect being due to either of the mineral acids. First appearance of the symptoms. — -When the quantity of the poison is considerable, and the solution concentrated, the symptoms begin immediately. If the quantity is small, and the solution weak, they may be delayed for some hours. Smallest fatal dose. — Less than Jtalf an cmnce has proved fatal ; but a smaller quantity has produced severe symptoms, and, on the other hand, recovery has taken place after the administration of two or three times as much. When active treatment is immediately adopted the patient often recovers. Shortest fatal period. — Death has taken place in ten minutes, the dose being one ounce. In one case, the subject of an inquest held by Mr. Wakley, it must have been nearly instantaneous. Death has taken place in one case at the end of twenty- three days, the dose having been half an ounce. Mortality. — The majority of cases prove fatal. A small number are recovered by prompt treatment. Treatment. — The proper antidote is chalk, suspended in water. Magnesia or its carbonate may also be used : in the absence of these the plaster of the apartment. Lime water and oil have been used * Of 11 cases of poisoning by oxalic acid reported in the Journals, 5 were accidental, and 6 suicidal. Of the accidental cases, 3 were by mistake for Epsom salts. Of 13 cases, 6 recovered and 7 died. 3 occurred in males and 10 in females. The duration of the fatal cases was as follows — 2 of a quarter of an liour, 1 of twenty minutes, 1 of less than half an hour, and 1 of eight days. The average duration of the first 4 cases was about twenty minutes. The reader is referred to the following cases : — Med. Gazette, i. T57 : v. 704: xxvii. 870: xxxi. 491. London Medical Reiwsltory, vi. 474: xi. 20; xil. 18. lancet, Dec. 15, 1827 : vol. ix. : x. 512 : xxxli. 748, xxxlii. 29. Guy's Hospital lieports, vil, 353. Edln. Med, and Surg. Journal, xxlv, 67, TARTARIC ACID. 349 with advantage ; but the alkalis are inadmissible. Warm water may- be given freely, after the use of the antidotes. If vomiting is not present, emetics of sulphate of zinc may be employed. The stomach- pump should either not be used, or it should be introduced with the greatest caution. BINOXALATE OF POTASH {Salt of Sorrel — Essential Salt of Lemons). This salt is a constituent of wood-sorrel and of other plants. Like oxalic acid itself, it is used for bleaching straw and removing ink- stains, for which purpose it, or a quadroxalate of potash, is sold under the name of " essential salt of lemons," for three halfpence the half ounce. As a poison it is scarcely inferior in activity to oxalic acid. It has been taken by mistake for the bitartrate of potash, or cream of tartar. Tests. — The salt is found in the form of colourless rhombic prisms. It has a sour taste, and strong acid reaction. It is much less soluble in water than oxalic acid, requiring 40 parts of water for its solution. It resembles oxalic acid in yielding a white precipitate with nitrate of silver and sulphate of lime, and it has the same reactions with sulphate of copper and the salts of lead. When the crystals are heated, they leave a white ash of carbonate of potash, which effervesces with nitric acid, forming nitrate of potash. Symptoms. — Those of poisoning by oxalic acid. In a case of re- covery from poisoning by a quarter of a tea-spoonful of this substance, lately reported by Dr. F. C. Webb, there was burning in the throat, a red tongue, intense thirst, no abdominal pain, vomiting after the lapse of two hours, severe pain in the loins, dysuria, great weakness of the legs, pain in the head, and cramps in the hands and legs. Fost-mortem, Appearances. — The same as in poisoning by oxalic acid. Treatment. — That of poisoning by oxalic acid. Smallest fatal dose. — Half an ounce. Shortest fatal period. — Eight minutes, in a lady recently de- livered. Mortality. — Like oxalic acid, it has proved fatal in the greater number of cases. 2. Tartaric Acid. This acid has been taken as a poison once in England and once in France. Tests. — This acid crystallizes in oblique rhombic prisms. It is colourless, and has a pleasant taste ; is soluble in five or six times its weight of water, and less soluble in alcohol. When heated, it first fuses, and then burns with a light red flame, giving out a peculiar 350 THE VEGETABLE ACIDS. odour, and leaving an abundant deposit of carbon. Carbon is also deposited when it is heated with strong sulphuric acid. The solution deposits feathery crystals; it yields no distinct pre- cipitate with nitrate of silver ; and it gives a white granular precipi- tate with the salts of potash. This precipitate (the bitartrate) is promoted in dilute solutions by friction of the sides of the vessel with a glass rod. Experiments on Animals. — These prove that tartaric acid is much less active than oxalic acid. In full doses it destroys life in less than an hour, with marks of great weakness, and palsy of the limbs. Symptoms. — In the large quantity of one ounce, dissolved in half a pint of warm water, the poison has proved fatal to a young male adult in nine days, with the ordinary symptoms of irritant poisoning. There are no specific symptoms. Post-mortem Appearances. — In the case just referred to, inflamma- tion of the greater part of the alimentary canal. Treatment. — By the same antidotes as oxalic acid, with the after- treatment proper to the class of irritants. The soluble salts of potash are not contra-indicated, as in poisoning by oxalic acid. Bitartrate of Potash {Cream of Tartar, Argol). — In large doses, such as two ounces and upwards, this salt is a decided poison. It has de- stroyed the life of an adult male in forty-eight hours, with the symptoms and post-mortem appearances of irritant poisoning. This substance is generally found as a white powder, sparingly soluble in water, and the solution has a feeble acid reaction. The powder when heated is con- verted into carbon and carbonate of potash, which latter effervesces with acids. The base may be identified by bichloride of platinum. It may be obtained as a sediment from organic liquids. The treatment is by copious demulcents, and by other remedies appropriate to the condition of the system. A dilute solution of the bicarbonate of potash may be given with advantage ; as it reduces the bitartrate to the con- dition of a harmless purgative salt — the neutral tartrate. 3, Citric Acid. Experiments on animals show that this acid is a more active poison than the tartaric acid. If a case of poisoning should occur by it, the treatment would be that of poisoning by oxalic or tartaric acid. 351 CHAPTER VI. SALTS OF THE ALKALIS AND EARTHS. The carbonates of potash, soda, and ammonia have been already exa- mined (see p. 340), the bitartrate of potash at p. 350, and the bin- oxalate of potash at p. 349 ; iodide of potassium will be treated of in Chapter X. The poisons, therefore, which remain to be examined in this chapter are : — 1. The Nitrate of Potash. 2. The Sulphate of Potash. 3. The Sulphate of Alumina and Potash. 4. The Sulphuret of Pot-assium. 5. The Chloride of Sodium. 6. The Chlorides of Lime, Soda, aud Potash. 7. The Salts of Baryta. The nitrate and sulphate of potash, the sulphate of alumina and potash, and the bitartrate of potash (p. 350), as also the chloride of sodium, resemble each other in being weak poisons, that is to say, in only acting as such in large doses. They are not generally considered poisons, and more than one of them has consequently been taken to discharge worms or to procure abortion. The sulphuret of potassium is a more active and fatal poison, and combines the irritant action of the base with the narcotic property of the sulphuretted hydrogen gas. NITRATE OF POTASH {Nitre, Saltpetre, Salprunelle). Poisoning with this substance is generally accidental, it being taken by mistake for sulphate of soda or sulphate of magnesia. Properties. — It is sold in two forms — in colourless or nearly colour- less crystals, or in crystalline masses ; and in white spherical or cir- cular cakes (salprunelle). It has a salt cool taste, and the familiar property of causing matters with which it is mixed to burn with de- flagration. Tests.— ^QQ nitric acid (p. 333). Symptoms. — It is only when given in large doses that nitre is in- jurious. I have repeatedly given it medicinally in doses of a scruple, and it has been administered in doses of two and three scruples, and even to the extent of half an ounce in a dose, without injurious effects. It has also been taken in doses of one or two ounces without pro- ducing any more severe effect than- a strong emetic or purgative. But several cases are on record in which doses of an ounce and upwards 352 SALTS OF TUE ALKALIS AND EARTHS. have produced very severe effects. In such doses the sym}>toms are those of acute irritant poisoning, with profuse discharges of blood by A'omiting and purging, and bloody urine. There is extreme prostration of strength, accompanied or followed in some instances by nervous symptoms, such as convulsions, slight trismus, tetanus, and stupor, loss of speech, sensation, and voluntary motion, and illusions of the senses, in one case there was chorea of two months' duration. Fatal Dose. — One ounce of the salt has proved fatal, and deatli has taken place in tlirec hours. In such cases the fatal event is due to collapse. Post-mortem Appearances. — Marks of violent'inflammation in the stomach and small intestines, with black patches in the stomach, re- sembling gangrene. In one case there was a small aperture in the stomach. Treatment. — As there is no antidote, the treatment is that of the irritants as a class (p. 318). Vomiting, if absent, should be promoted by emetics, followed by the abundant use of diluents, or the stomach- jmmp may be used. Antiphlogistic remedies may be required, to combat high inflammatory action, sedatives if nervous symptoms are present, and stimulants in case of collapse. SULPHATE OF POTASH {Sal (le duohus, Sal Folychrest). This salt has more than once proved fatal when administered in large doses. In a French case, ten drachms given, in divided doses, to a lady within a week of her confinement proved fatal in two hours, with the symptoms and post-mortem appearances of irritant poisoning. In a suicidal case, in which Dr. Letheby gave evidence, ^^iss of the poison gave rise to marked appearances of irritation in the stomach and small intestines. Tests. — The salt is readily identified by the nitrate of baryta, as a test for the acid, and the bichloride of platinum as a test for the base. Treatment. — That of irritant poisoning (p. 318). SULPHATE OF ALUMINA AND POTASH [Alum). This substance has been very rarely taken as a poison. Properties. — It is found in commoce as a colourless crystalline mass, or in the calcined state as a white mass or powder. It is also to be met with as iron-alum. It has a sour taste, and yields an acid solution, which is readily distinguished from dilute free acids by evaporation. If a drop of a solution of alum is placed on a slip of glass, it commonly leaves on evaporation a beautiful compound crystal, consisting of straight parallel columns crossed at right angles by short lines, and surrounded by rectangular crystalline forms. These compound crystals are blended w^ith right octahedra, more or less perfectly formed. From saturated or strong solutions of alum the CHLORIDES OF LIME, SODA, AND VOTASH. 353 crystals are deposited either as right octahedra or as cubes, and large masses of crystals, consisting of piles of octahedra, either colourless or coloured, are familiar objects in the shops. Tests. — The sulphuric acid may be detected by the solution of nitrate of baryta ; the alumina is thrown down by liq. potassae, as a white precipitate, soluble in an excess of the precipitant ; and the potash may be detected by the chloride of platinum. Si/mptoms. — Those of simple irritant poisoning (p. 317). Treatment. — That of simple irritant poisoning (p. 318). After emptying the stomach by the stomach-pump or by emetics, lime- water may be given with advantage. SULPHURET OF PQTASSiUM {Liver of Sulphur). The alkaline sulphurets are active poisons, containing an irritant base with a nai'cotic gaseous acid. Properties. — It is found in the shops in dirty green masses, or in powder of the same colour. It yields a yellow solution, and has a strong odour of sulphuretted hydrogen. Tests. — On the addition of an acid the gas is disengaged, and pro- duces its characteristic effect on paper moistened with acetate of lead. Symptoms. — Those of acute irritant poisoning, with the addition of convulsions, or of stupor. The breath, and the matters discharged from the stomach and bowels, have the odour of sulphuretted hydrogen. Death may occur in so short a time as a quarter of an hour. Post-mortem Appearances. — Redness of the stomach and duodenum, and deposit of sulphur on the mucous membrane. The surface of the body very livid. The lungs gorged with dark blood. Treatment. — Dilute solutions of chloride of soda or lime (bleaching liquids) should be immediately administered. The remainder of the treatment is that of irritant poisoning. CHLORIDE OF SODIUM [Common Salt). Properties and Tests. — The salt is soluble in water, and the solu- tion on evaporation yields cubic crystals. The acid is detected by the solution of nitrate of silver, which throws down the white chloride. The base may be detected by the negative reaction with the bichloride of platmum. Symptoms. — Those of irritant poisoning (p. 317). Treatment. — That of irritant poisoning (p. 318). CHLORIDES OF LIME, SODA, AND POTASH {Bleackinj Powders and Liquids). The chloride of lime, hypochlorite of lime, or common bleaching powder ; the chloride of soda, hypochlorite of soda (in solution), * 2 A 354 SALTS OF THE ALKALIS AND EARTHS. Labaraque's or Fincham's liquid ; and the chloride of potash, hypo- chlorite of potash, or Eau de Javelle, are all poisonous. Properties. — All these substances and solutions yield chlorine spon- taneously or on the addition of an acid, and they have a strong odour of the gas. The gas is readily identified both by its peculiar odour and by its bleaching propei-ties. The symptoms, post-mortem appearances, and treatment in poison- ing by these substances would be those proper to the class of irri- tants. SALTS OF BARYTA. The salts of baryta have been occasionally taken as poisons. The muriate and the carbonate have both proved fatal. The nitrate and acetate are also possessed of poisonous properties. Properties. — The chloride of barium is found in commerce irregu- larly crystallized in tables. It is permanent in the air and soluble in water, and has an acrid taste. The carbonate is commonly found in the shops as a fine white powder, insoluble in water, but soluble with effervescence in dilute acids. Though insoluble in water, it is readily decomposed by the free acids of the stomach. Tests. — Baryta is piecipitated from its solutions as a white car- bonate by carbonate of potash, and as an insoluble white sulphate by sulphuric acid or the alkaline sulphates. Oxalic acid does not precipi- tate baryta from dilute solutions. The acids in combination with the base are easily distinguished : the carbonic acid by effervescing on the addition of dilute mineral or vegetable acids ; the muriatic acid by nitrate of silver ; the nitric acid by precipitating the base with sulphate of potash, when nitrate of potash will remain in solution ; and acetic acid by the odour of the vapour disengaged on adding dilute sulphuric acid. Symptoms, — Those of irritant poisoning (p. 317), with the addition of nervous symptoms in a maiked form, such as violent cramps and convulsions, headache, excessive debility, dimness of sight and double vision, noises in the ears, and violent palpitation of the heart. The occurrence of such symptoms would justify the removal of this poison to the class of specific irritants. Post-mortem Appearances. — Those of irritant poisoning (p. 317). In one case, in which death took place in two hours, the stomach was found perforated. Treatment. — The free administration of the sulphate of soda or of- magnesia as an antidote, with the use of emetics and the stomach- pump. The after-treatment is that common to the whole class of irri- tants. (See p. 318.) 355 CHAPTER YU. VEGETABLE IRRITANTS. 1. Purgative medicines. 2. Juniperus sabina. 3. Taxiis baccata. 4. Daphne mezeveum. 5. Arum maculatum. 6. Colchicum autumnale. 7. Veratrum album (veratria). 8. Helleborus niger, 9. Diseased and decayed vegetable matters. This group consists, 1. Of substances belonging to the class of pur- gative medicines — Aloes, colocynth, gamboge, jalap, ^cammony, castor-oil seeds, and croton seeds and oil. 2. Of other vegetable irri- tants not commonly used as aperients — Savin, yew, mezereon, arum maculatum, colchicum, and hellebore. 3. Diseased and decayed vege- table matters. 1 . Of the first group, which comprises the more active purgatives, it will suffice to state that when given in large doses, or to a pei'son suffering from great debility, they may act as poisons. All those enumerated above, given alone or in combination, have proved fatal. They owe their poisonous property chiefly to the oily or resinous matters which they contain. Two of the poisons in the second group (colchicum and stavesacre) owe their irritant properties to alkaloids (colchicina and delphinia) ; and the poisonous eiTects of another vegetable irritant (hellebore) are said to be due to a neutral crystallizable principle (helleborine). The vegetable irritants are often identified in the contents of the alimentary canal by fragments of their leaves, fruits, or seeds. The symptoms produced by this class of poisons are those of irritation of the alimentary canal — vomiting and purging, with pain in the abdo- men, tenesmus, and strangury. The patient falls into a state of collapse, attended occasionally with drowsiness and slight nervous symptoms. The post-mortem appearances are those of inflammation of the ali- mentary canal in various degrees and stages — redness, ulceration, softening, and effusion of dark blood into the submucous tissue. The treatment proper to the whole class of vegetable acrids consists in the administration of emetics when vomiting is absent, followed by the free use of diluents ; in local or general blood-letting when inflam- matory symptoms run high, and in the use of stimulants or narcotics if collapse or nervous symptoms are present. 356 VEGETABLE lERlTANTS. 2. Savin (Juniperus sabina). — This is a small indigenous bushy shrub, yielding a round purple fruit about the size of a currant. It has a peculiar strong odour, and an acrid taste ; and owes its irritant properties chiefly to an essential oil readily obtained from the fresh tops of the plant by distillation with water. This oil, and an ointment made of the freshly-bruised plant, are in the London PhaiTnacopceia. The leaves of the plant, in powder or infusion, and the oil, are often given with a view to procure abortion ; but it has more frequently proved fatal to the mother than effectual in destroying the child. Savin in also in occasional use as a vermifuge. Symptoms. — Those of irritation of the alimentary canal. There is severe pain in the belly and vomiting, and sometimes strangury, but diarrhoea is rare. Salivation and insensibility are among th^ occasional symptoms. Fost-mortem Appearances.— Those of acute inflammation of the alimentary canal ; and the green powder is often found mixed with the contents of the stomach and bowels. On drying and rubbing this powder it gives out the peculiar odour of the plant, and the hard thick parts of the twigs exhibit under the microscope the ordinary charac- teristics of coniferous wood. Watery solutions of savin yield a deep- green colour with the permuriate of iion. The treatment of poisoning by savin is that proper to the whole class of irritants (p. 318). 3. Yew (Taxus baccata). — The leaves and ben-ies of this tree are poisonous. The leaves have proved fatal to animals, and the leaves and berries to man. The leaves, in substance or in infusion, are sometimes given as a vermifuge or abortive. Symptoms. — Those of irritant poisoning, with the addition of ner- vous symptoms, such as insensibility and convulsions, which may perhaps justify us in classing the yew among the narcotico-acrids. Death seems to take place from collapse, when it happens in a short time ; but if at a later period, the cause of death appears to be inflammation of the alimentary canal. The leaves have proved fatal to an adult in fourteen hours, and the berries to a girl five years old in four hours. Post-mortem Appearances. — Those of irritation of the alimen- tary canal. The leaves or berries are generally found in the stomach, and may be identified by their shape and appearance. The leaves are lancet-shaped ; and the berries, which are about the size of a pea, consist of a hard, brown, egg-shaped seed, surrounded by a colourless viscid juice, enclosed in a light red covering. The juice has an acid reaction and a nauseous taste. 4. Mezereon (Daphne mezereum). — This is a cultivated garden shrub, yielding a bright red berry, possessing highly irritating properties, and in large quantities acting as a poison. The berries, from their beautiful colour, attract the notice of children, and have been mistaken for currants. They contain a single ovate seed composed of two plano- convex cotyledons enclosed within the coat. Five or six of the berries ARUM. COLCHICUM. 357 are sufficient to produce serious effects. The bark of the root is an ingredient in the compound decoction of sarsaparilia. The sj/mptoms, post-mortem appearances, and treatment are those of irritant poisoning, 5. Arum (Arum maculatum, lords and ladies, cuckoo-pint). — The green spotted leaves of this plant, shaped like the head of an arrow, appear early in spring in hedge-rows, woods, and shaded spots, the green spathe, with its purple column enclosed, in May, and a cluster of bright-red berries alone, towards the end of summer. The root is tuberous and somewhat heart-shaped, and, in common with all other parts of the plant, is highly acrid and irritating. The juice applied to the tongue causes acute darting pain, as if it were pierced with sharp needles ; and in the case of three children who ate of the leaves of the plant, the tongues were so swollen as to render swallowing diffi- cult. Two of the children died in twelve and sixteen days respectively. The third recovered. The poisonous properties of the plant are wholly dissipated by heat ; and the roots, first steeped in water, and then baked and powdered, constitute the " Portland sago." The symptoms, post-mortem appearances, and treatment are those proper to irritant poisoning. 6, CoLCHiCUM (Colchicum autumnalc, Meadow saffron), — This plant grows in moist meadows in every part of Europe, It flowers in autumn, and throws out its leaves in spring; and it has a fibrous root attached to the underside of an underground stem or corm. The fruit, which ripens about midsummer, contains a number of round seeds. The corm and seeds are used in making several preparations of the Pharmacopoeia — the fresh corm for the extract, and acetic extract, the dried corm for the vinegar and wine, and the seeds for the simple and compound tinctures of colchicum. The corm has been taken by mistake for onions, and the seeds, wine, and tincture have also been taken in poisonous doses. The symptoms are sometimes slow in showing themselves, even when large doses of the wine or tincture are taken ; but in other cases they begin almost immediately, and death may take place in as short a time as seven hours. The symptoms are those pf irritation of the alimentary canal, with collapse. Nervous symptoms are of rare occurrence. The post'mortem appearances are those common to simple irritant poisoning; and the treatment is that proper to poison- ing by the irritants (p, 318), with the addition of the free use of stimulants to counteract the extreme debility. The seeds of colchicum are round in shape, brown Fig- 15. in colour, hard, and shrivelled on the surface. They are of the size figured in the annexed woodcut, and weigh eight, ten, or twelve to the grain, Colchicum owes its poisonous properties to an alka- loid, allied to veratria, and named colchicina, of which less than half a grain has proved fatal to an adult. 358 VEGETABLE IRRITANTS. Hellebore. — There are several species of hellebore — the Helleborus niger, viridis, and foetidiis, and the Veratrum album, or white helle- bore. Two of these, the Veratrum album, and the Helleborus niger, are of some importance as poisons. 7. Vkratrum album (White hellebore). — This plant is not indigenous. Its rootstork and radicles are employed in making the Vinum Veratri of the Pharmacopoeia. Every part of the plant is poisonous ; but the powder of the root, or an infusion made from it, is the preparation which has been most commonly taken as a poison. This powder, which somewhat resembles powdered jalap in colour, has an acrid, bitter taste, and strongly irritates the nostrils. It is, accordingly, sometimes used, mixed with starch, as an errhine ; but its principal use is to destroy vermin on the skin or hair. The symptoms, post-mortem appearances, and treatment are those proper to irritant poisoning (p. 317), with a tendency to death by collapse. As little as 20 grains of the powder has destroyed life in three hours. It owes its poisonous properties chiefly to the alkaloid veratria. Veratri A. — This alkaloid is contained in the seeds of the Asagraa officinalis (Cebadilla), as well as in the rootstock of the Veratrum album. It is prepared from the seeds of the Asagraa, and is in the London Pharmacopoeia. It violently irritates the nostrils and skin, and is applied externally iu small quantities, and given internally in doses of -y'.j grain. Even in this small quantity it requires to be used with caution. One-sixteenth of a grain is believed to have produced a state of dangerous collapse (Taylor). The alkaloid veratria is sold as a powder. It is not crystallizable. It burns away without residue, is nearly insoluble in cold, and sparingly soluble in hot water, spar- ingly soluble also in ethei-, but readily dissolved by alcohol. It has a slight alkaline reaction, forms soluble salts with the acids, and is slightly reddened by nitric acid, and changed to a deep crimson by sul- phuric acid. 8. Helleborus niger (Black hellebore, Christmas rose). — This plant derives its name from the dark or black colour of its root. Hence, also, the name " Melampodium" of the old Pharmacopoeias. It grows in shady woods, and flowers in January, as the * Christmas rose.' The leaves and roots are both poisonous ; and the powdered root is a brisk purgative, and, as well as the leaves, is a favourite but dangerous worm-medicine with the vulgar. The tincture of helle- bore is officinal. The symptoms, post-mortem appearances^ and treatment are those proper to irritant poisons generally (p 3 17), with violent action on the bowels, and marked symptoms of collapse. 9. Diseased ami decayed vegetable matters. — A few cases have occurred of poisoning by spoiled vegetables; and bread made of wheat, rye, or barley, when spoiled or mouldy, has been known to act as an irritant poison, causing flushed face, dry tongue, violent colic pains, SUPPLEMENTAL LIST. 359 urgent thirst and headache, vomiting and diarrhoea, exhaustion and drowsiness. The»e poisons are classed by Dr. Christison with the narcotico-acrids, to which class tlie ergot of rye certainly belongs. Besides the vegetable irritants briefly noticed in this chapter, there are others of less importance, of which it must suffice to append a list. Some of them have produced the effects of irritants in the human subject, and have proved fatal, while others are inferred to be poisonous from their effect upon animals, or from direct experiment. A minute description of these poisons and of their effects must be sought for in works on toxicology. Most of them will be found figured, with brief descriptions of their effects, in Johnson's ' British Poisonous Plants.' The following is the list in question : — Anemone pulsatilla, or pasque flower, (also the A. nemorosa, A. hortensis, and A. coro- naria, with other species,) ; Bryonia dioica, red-berried, common, or white bryony ; Tamus communis, or black bryony ; Caltha palustris, or marsh marigold ; Chelidonium majus, or celandine ; Daphne laureola, or spurge laurel ; Euphorbia lathyris, or caper spurge (also other species, as the E. peplus, and E. helioscopia) ; Helleborus viridis, or green hellebore ; Hyacinthus nonscriptus, or wild hyacinth ; Mercurialis perennis, or dog's mercury ; Narcissus poeticus, or nar- cissus; Kanunculus acris, bulbosus, sceleratus, and other species of the crowfoot, or buttercup ; and the Sambucus nigra, or elder. Besides the foregoing, which are indigenous plants, the Jatropha curcas, or physic nut of the West Indies; and the Hippomaue man- cinella, or manchineel, with other species of the same (as the H. figlandulosa, and H, spinosa), may be mentioned as possessed of highly irritating properties. (See Christison, chapter on Vegetable Acrids.) 360 CHAPTER VIII. ANIMAL IRRITANTS. 1. CANTHARIDES. 2. POISONOUS FISH. 3. DISEASED AND DECAYED ANIMAL MATTER. Among the poisonous substances derived from the animal kingdom some possess independent properties, others owe their poisonous effects to a change wrought by putrefaction. Of the first class cantharides is the principal member. Poisonous fish occupy a less important position. To the second class belong the several kinds of diseased and decayed animal matter. I. Cantharides. The Cantharis vesicatoria, Spanish fly, or blister beetle, distinguished by the shining golden green colour of the head, legs, and wing-cases, furnishes a very active irritant poison. It is the active ingredient of several preparations of the London Pharmacopoeia — of the tincture which is administered internally ; and of the acetum, ceratum, un- guentum, and emplastum cantharidis, which are applied externally. It is characterized by its energetic action on the urinary and generative organs. The powder and tincture are given to procure abortion, for lascivious purposes, or merely by way of a joke ; and both powder and plaster have been taken by mistake. It has also produced severe effects when applied externally. When it has been administered in powder, the blistering fly may be detected in the contents ot the stomach by the glistening golden or green colour of some of the particles, which may be readily seen by the lens or under the microscope ; or it may be dissolved in ether or chloroform, evaporated to the thickness of an extract, and applied to the skin, or to the lip. If a blister is raised, it gives convincing evi- dence of the presence of cantharides. By these two tests Barruel succeeded in detecting cantharides in some cakes of chocolate, of which a part had been maliciously given to several persons. The fly owes its poisonous property to an alkaloid, canthdradin, of which one giain is afforded by half an ounce of the powder; and the one-hundredth part of a grain will raise blisters on the lip. The chemical properties of this principle are not characteristic. Symptoms. — Soon after swallowing the poison, a burning pain and POISONOUS FISH. 361 constriction of the throat, speedily followed by a similar burning pain in the pit of the stomach, increased by pressure, and extending at length over the whole abdomen, accompanied by excessive pain in swallowing, dryness of the fauces, great thirst, copious discharge of blood or bloody mucus from the stomach, mixed with shining, green particles, and, in less quantity, from the bowels ; tenesmus, pain in the loins, distressing strangury, bloody stools and urine, priapism, with swelling, and inflammation of the genital organs. The patient is ex- tremely restless, the breathing laborious, the pulse quick and hard. Occasionally headache, delirium, and convulsions, and coma are super- added. Among the occasional symptoms recorded are blisters of the mouth, salivation, vomiting of tenacious mucus taking the shape of the gullet, or of the mucous membrane itself, redness of the eyes, and lachrymation, nausea, and an albuminous state of the urine. Wlien given as a medicine, in the form of tincture, small doses, such as four or five drops, produce a marked effect on the urinary organs, curing incontinence of urine, sometimes without causing pain. On the other hand, very large quantities, as six ounces of the tincture, or two drachms of the powder, have been taken without bad effect, a fact only to be accounted for by the badness of the preparation. The smallest quantity of the tincture which has proved fatal is one ounce, and two doses of the powder of twenty-four grains each, taken at an interval of a day, have destroyed life after producing abortion. Post-mortem Appearances. — These correspond with the symptoms just detailed. There are marks of inflammation in different degrees and stages in the whole length of the alimentary canal, and in the urinary and genital organs. The stomach is sometimes inflamed in patches, where the powder has adhered. The brain has been found gorged with blood. The powder may be found in the stomach for long periods after death. According to Orfila and Leseur, it may be found unchanged after an interment of nine months. Treatment. — There is no antidote to this poison. Vomiting must be excited and encouraged by emetics and warm liquids ; and the poison must be removed from the bowels by full doses of castor oil. The free use of diluents, with oily or demulcent injections into the rectum and bladder, and leeches or bleeding, if the inflammatory symptoms run high, constitute the remainder of the treatment, fiaudanum may be advantageously added to the injections, or supposi- tories of opium may be introduced into the rectum. 2. Poisonous Fish. Several kinds of fish belong to the class of irritant poisons. Some of these are constantly poisonous, others occasionally so, and others, again, act injuriously on certain persons only. The most important of these poisonous fish is the common mussel, which becomes poisonous in certain circumstances not yet well under 362 ANIMAL IRRITANTS. stood. The symjttoms generally come on after an interval of one or two hours, with swelling and itching of the eyelids, and watering of the eyes, and an eiiiption on the skin, in most cases closely resembling common nettle i-ash, and attended with intense heat and itching. Dyspnoea generally follows, but occasionally precedes these symptoms ; there is extreme weakness ; and in fatal cases delirium, convulsions, and coma have supervened. Symptoms of irritation of Ihe stomach are not always present, but in some instances there have been nausea, pain in the pit of the stomach, vomiting, and difficulty in swallowing. The treatment will consist in the free use of emetics, purgatives, and diluents. Ether may also be given with advantage. Instances are on record in which oysters, eels, and salmon have produced injurious effects. The richer fish also habitually disagree with some persons. When fish owe their poisonous properties to putrefaction, they belong to the next class of poisons. 3. Diseased and Decayed Animal Matter. There is a disease prevalent among cattle on the Continent, but less known in England, which consists in the formation of large boils upon different jmrts of the body. The flesh of animals which have died of this disease has often produced severe effects by contact with the skin, and when eaten has destroyed life either by producing violent cholera, or by creating a similar disease to that under which the animal laboured. The glanders communicated to man from the horse, and the diffuse inflammation excited by punctured wounds inflicted in dissection, or in preparing meat for the table, are familiar examples of the effect of diseased animal matter applied externally to the human body. Decayed Animal Matter is a common cause of severe and dangerous symptoms allied to those of irritant poisoning. The articles of food which have most frequently acted as poisons are sausages (especially those made of liver and blood), bacon and ham, cheese, and goose The symptoms raiely come on till the lapse of three or four hours. Jn some instances the irritation oi the alimentary canal is accompanied by symptoms of collapse, in others by narcotic symptoms, which would perhaps entitle these poisons to a place among the narcotico-acrids. It appears that the poisonous quality of the food is developed only in the first stages of putrefaction, but disappears when that process is far advanced. The milk of cattle fed in particular pastures, containing poisonous plants, is said to acquire poisonous properties, just as the honey of bees, which feed on certain poisonous flowers, produces delirium and symptoms of narcotic poisoning. The treatment of these cases, after the removal of the poison from tlie stomach, would be determined by the nature of the symptoms present. 363 CHAPTER IX. IRRITANT GASES. 1. Nitrous-acid Gas. (See p. 335.) 2. Sulphurous-acid Gas. 3. Hydrochloric-acid Gas. 4. Cihlorine. 5. Ammonia. (See p. 343.) The irritant gases have the common property of irritating and in- flaming the eyes, throat, and whole extent of the air-passages. In a concentrated form they may produce fatal spasm of the glottis. 2. Sulphurous-acid Gas. This gas^ possesses highly-irritating properties. It is one of the products of the combustion of common coal, and contributes to the fatal result when coal is burnt in close apartments. It is also the chief cause of the irritating gusts which issue from the baker's oven, and as such contributes to produce the diseases of the chest to which the London bakers are peculiarly liable. 3. Hydrochloric-acid Gas. From experiments made on plants by Drs. Turner and Christison,' and from experiments on small animals by Messrs. Rogerson (see chapter on Poisonous Gases in ' Christison on Poisons'), it is evident that this gas is possessed of highly-irritating properties, and that if inhaled by the human subject it would destroy life, as certainly as any other of the irritating gases. 4. Chlorine. This gas is largely used in bleaching, and, in the sick room, as a disinfectant. It has highly-irritant properties, and produces violent irritation in the eyes, nostrils, air-passages, and throat. In a case cited by Christison, great relief was obtained by the inhalation of a small quantity of sulphuretted hydrogen gas. From information collected by Christison, it appears that men who are in the habit of inhaling air impregnated with chlorine become gradually accustomed to its use, though they suffer from dyspeptic complaints and acidity, and lose flesh; but nevertheless many of them attain to an advanced age. 3G4 CHAPTER X. SPECIFIC IRRITANTS. This group comprises the metalloidal poisons and their compounds, and the preparations and compounds of most of the metallic poisons. The salts of some of the metals, such as zinc, appear to be simple irritants, and not to occasion any remote specific effects. But as they belong to the class of metallic poisons, it has not been thought expedient to separate them from the more important members of the same class. The leading poisons belonging to this class are treated in separate chapters. The metalloidal poisons, phosphorus and iodine, are treated in the present chapter. 1. PHOSPHORUS. Properties. — It is usually found in the shops as small cylinders, preserved in water. It has the consistence and appearance of wax, is insoluble in water, but soluble in oils, in alcohol, and in the ethers : also remarkably soluble in the bisulphide of carbon. It burns at a low temperature with yellow flame and dense white smoke, and is luminous in the dark. A paste, consisting of flour, sugar, and phosphorus, sometimes coloured with Prussian blue, is sold as a poison for rats. Phosphorus has been given medicinally in over-doses, and is often taken in France, and sometimes in England, as it exists on lucifer matches ; but its property of shining in the dark, which it does not lose by admixture with articles of food, and its peculiar odour and taste, unfit it for the service of the murderer. Symptoms. — Those of acute irritant poisoning (p. 317). The taste of the poison resembles that of garlic, and the breath has an odour of the same substance. The matters rejected from the stomach and bowels have the same odour, and they are sometimes distinctly luminous in the dark. In some cases the nervous system seems to be strongly affected ; and, in one instance, the symptoms resembled those of hydro- phobia. Irritation and excitement of the genital organs are among its occasional effects. Post-mortem Appearances. — Those of acute irritant poisoning, in- cluding extensive destruction of the coats of the stomach, with softeu- ing, ulceration, and perforation. The contents of the alimentary canal are phosphorescent, and the effluvia from a body advanced in putre- faction have been observed to have the same property. Poisonous Dose. — From one to three grains. Period of Death. — In acute cases, a few hours. In one instance, four hours. In chronic cases life may be prolonged for seveial days. Treatment. — After the stomach-pump or emetics, hydrate of mag- nesia suspended in mucilagino'is drinks, followed by aperients of the SPECIFIC IRRITANTS. 365 sulphate and carbonate of magnesia. The rest of the treatment is that of irritant poisoning (p. 318). In the chronic form of poisoning by phosphorus, the patient wastes away under prolonged dyspepsia and diarrhoea, with hectic fever. Ex- posure to the vapour of phosphorus, in the process of making lucifer matches, causes severe irritation of the lining membrane of the air- passages, and leads to caries of the teeth and necrosis of the jaw. The discovery of the important fact that red, amorphous, or allotropic phosphorus, though possessing the same chemical composition, is not poisonous, may lead to the disuse of common phosphorus for manu- facturing pui'poses. The substitution of chlorate of potash is, how- ever, to be pieferred. Phosphorus in Organic Mixtures. — Several methods for detecting the poison have been proposed. Mitscherlich adds to the organic matter water, and a small quantity of sulphuric acid, and distils it in the dark from a flask, through a tube kept cool by a stream of water. At each condensation of the vapours in the tube a luminous appear- ance is perceived. Another plan consists in converting the phosphorus into phosphoric acid, by boiling with nitric acid diluted with three parts of water. A third plan, suggested by Dr. Taylor, consists in digesting the organic matters in bisulphide of carbon, and allowing the solution to evaporate spontaneously. The phosphorus remains in the form of small globules, which sometimes take fire spontaneously. (' On Poisons,' 2nd edit., p. 350.) 2. IODINE. Properties. — This is a scaly substance, not unlike iron filings in appearance, of a peculiar and disagreeable odour, giving off irritating violet fumes when heated, striking a fine blue colour with a solution of starch, and staining the skin and lining membrane of the intestinal canal a yellowish brown, which stain is removed by liquor potassas. It is found in the shops in substance, as a tincture, and as a compound solution with iodide of potassium as a solvent. It is largely used in medicine as an external application, and internally in combination with potash, as iodide of potassium. Symptoms. — A disagreeable acrid taste, with a sensation of heat, dryness, and constriction in the thj-oat, in the act of swallowing, fol- lowed by the symptoms of acute irritant poisoning (p. 317). The discharges, of a deep yellow tint, are often mixed with blood. In chronic poisoning, produced by the prolonged employment of iodine or its preparations in medicinal doses, the symptoms, in addition to those of irritation of the alimentary canal, are tremors, palpitation, gradual absorption of the testicles, mamma;, and other glandular structures, ptyalism, increase of almost all the secretions, priapism, and enlargement and tenderness of the liver. These symptoms, which are not present in all cases of iodism, have been more than once pro- duced by small doses, administered for a few days at a time. 366 IODIDE OF POTASSIUM. Post-mortem Appearances. — Those of acute irritant poisoning (p. 317). Enlargement of the liver. Treatment. — That of irritant poisoning (p. 318), including the free use of a weak solution of carbonate of soda, and of diluents containing starch, such as arrow-root. 3. IODIDE OF POTASSIUM (Ilydriodate of Potash). Properties. — Iodide of potassium is a crystalline substance, having a peculiar faint odour. Its ciystalline form is a cube. The crystals, when pure, are white, permanent in the air, and very soluble in water and alcohol ; but when impure, of a yellowish colour, and deliquescent. Tests. — Strong nitric or sulphuric acid turns the crystals browu by liberating the iodine, which on the application of heat lises in violet vapours. In Solution it has the following reactions: — corrosive sublimate yields a fine carmine-red precipitate, the iodide of mercury ; acetate of lead, the yellow iodide of lead ; the subnitrate of mercury, the yellow subiodide of mercury, which gradually changes to a dirty brown; sulphuric and nitric acids change the solution to a brown ; and, on the addition of starch, to a characteristic blue. The base may be detected by the bichloride of platinum. In Organic Mixtures. — Transmit sulphuretted hydrogen through the mixture to convert free iodine into hydriodic acid. Drive off the excess of gas by a gentle heat, add potash in excess, filter, and evaporate to dryness. Place the residue in a covered crucible and char it at a low red heat ; reduce the charred mass to powder, treat it with distilled water, and filter. Concentrate the liquid by evaporation, and apply the test of starch and sulphuric acid. By this means very minute quantities of the poison ma)' be detected. Symptoms. — When given as a medicine, and in small doses, the hydriodate of potash sometimes acts injuriously, in consequence of peculiarity of constitution. Alai-ming symptoms have been produced by two or three doses of two or three grains, or a single dose of five grains ; but the medicine is being constantly given in five-grain doses three times a day to large numbers of patients, without producing any bad effects. The symptoms are vomiting and purging, severe griping pains in the abdomen, watering at the nose and eyes, swelling of the face, headache, dryness of the throat, intense thirst, difficulty of breathing, frequent pulse, and great prostration of strength. In less marked cases the symptoms resemble those of a severe cold. Ptyalism is an occasional symptom. In one case, in which I ascertained that no preparation of mercury had been given, all the characters of mercurial salivation were present. Treatment. — The poison should be promptly removed by the use of emetics, or by the stomach-pump. The after-trpatment is by diluents, with antiphlogistic remedies if necessary. 361 CHAPTER XI. 1. ARSENIC AND ITS PREPARATIONS. 2. ANTIMONY AND ITS PREPARATIONS. 3. MERCURY AND ITS PREPARATIONS. 4. LEAD AND ITS PREPARATIONS. 5. COPPER AND ITS PREPARATIONS. 6. ZINC, TIN, SILVER, IRON, BISMUTH, CHROME, AND THEIR PREPARATIONS. Aksenic is by far the most important of the metaUic poisons, whether we measure its importance by the extent to which it is diffused, the number and variety of its applications in medicine and the arts, or the frequency of its use as a poison. Arsenic and its compounds enter largely into the composition of the earth's crust. It is found as metallic arsenic, as arsenious acid, in the form of the two sulphides, realgar and orpiment, and as a con- stituent of several ores of iron, copper, silver, tin, zinc, nictkel, and cobalt. The greater part of the arsenious acid of commerce is pre- pared from an arsenical sulphide of iron, known as mispickel, or arsenical pyrites ; the remainder from the roasting of ores containing arsenic, especially those of copper and cobalt. The vapours of arsenious acid are diffused in the atmosphere, in large quantities, in the neighbourhood of some smelting furnaces. Arsenic has also been found in several soils, in plants grown upon them, and in some mineral waters and running streams. As the iron pyrites, or mundic, which is so largely employed in the manufacture of oil of vitriol, contains arsenic as an impurity, much of the sulphuric acid of commerce is tainted with arsenic ; and this being, in its turn, very largely used in the manufacture of nitric, hydrochloric, and other volatile acids, of sulphate of soda, as a pre- liminary to the making of the carbonate of soda, and for other pur- poses, many liquid and solid substances in common use in medicine and the arts are impregnated with arsenic. In the application of the tests presently to be described, the two metals, zinc and copper, the two acids, the sulphuric and the hydrochloric, and the sulphuret of iron have all been found to contain arsenic. Arsenic acid and the alkaline arseniates are in use as mordants, and in some dye-works to such an extent as to poison the waters of the streams into which they discharge their refuse ; and even to taint the water-supply of towns. Arsenious acid, the most important of the compounds of arsenic, is very largely employed in the arts. It is used in the manufacture of glass, to improve the quality of the " metal," and in the making of white enamel. Farmers use it to preserve grain for seed, and many 368 ARSENIC AND ITS PREPARATIONS. of the dipping compounds for sheep owe their efficacy to the large quantity of arsenious acid which they contain. Grooms give it to horses to improve their coats ; and there is no longer any doubt that some Styrian peasants habitually take arsenious acid in quantities exceeding the smallest poisonous dose,* Shipbuilders mix it with tar to protect timber from worms. It is largely employed to kill rats and vermin, flies, and moths. It has long been used in the manufac- ture of composition candles, and recently to prevent the furring of steam-boilers. The metal arsenic is mixed with lead in small shot. The preparations of arsenic have been mixed by accident, or in ignorance, with articles of confectionary : arsenious acid with lozenges, orpiment in Bath buns, and Scheele's green with blancmange. Scheele's green is also very largely used in the manufacture of green papei-s. Areenical preparations are administered internally, in Fowler's solution, and the liq. arsenici chloridi, for the cure of ague and inter- mittent disorders, and of obstinate skin diseases ; and white arsenic mixed with large quantities of calomel, or otherwise minutely sub- divided, is sometimes applied externally in lupus and cancer. The preparations of aisenic which ai-e of most interest in a medico- legal point of view are, the white oxide or arsenious acid, the yellow sulphui-et or orpiment, the green arsenite of copper or Scheele's green, and the arsenite of potash contained in Fowler's solution. Of these the arsenious acid is by far the most important ; and it will have to be examined, accordingly, with great care, and in much detail. As all our processes of analysis include the production of the metal arsenic as a means of identification, it will be expedient to preface the examination of the several preparations of arsenic by some account of the most important properties of the metal. The metal arsenic sublimes at the low temperature of 356° Fahr. When the sublimation is conducted in close vessels, it is deposited on cooler surfaces unchanged ; but when heated in contact with air it is deposited as the white oxide, or aisenious acid, or as a mixture of the acid with the metal. The metal is also deposited un- changed when it is sublimed in an atmosphere of carbonic acid. The metal in subliming gives out the odour of garlic. It shares with antimony the property of combining with nascent hydrogen, to, form the arseniuretted hydrogen gas, which gas, when heated or burned, gives up the pure metal to cool surfaces ; and it shares with several other metals the property of being reduced and deposited on copf)er boiled in an acid liquor containing any of its prepaiations. All these properties of metallic arsenic are displayed in operations on the small scale, in which we use the spirit-lamp and small reduction- * Dr. Roscoe, in a paper read to the Manchester Philosophical Society, Oct 2c, 1860, brings forward conclusive evidence in support of this siatenient, and adduces well-authenticated instances in which the poison was swallowed to the amount of 43 and 5^ grains at a time. AESEXIOUS ACID. 369 tube. The vapour of the metal has the garlic oJour : it is deposited on cooled surfaces as arsenious acid, when the tube contains atmo- spheric air ; and as pure metal when it is filled with carbonic acid gas : it forms a shining metallic crust or stain on a surface of porcelain when the burning jet of arseniuretted hydrogen is directed upon it from Marsh's apparatus ; it leaves a similar stain in the tube through which the gas is transmitted, when heated by the spirit lamp ; and it forms a metallic coating to copper foil when -^^S- 15. boiled in liquids containing it and acidulated with hydro- ^« chloric acid, according to Remsch's process. The vapour of ®^«*® the pure unmixed metal is deposited on cooled surfaces as ^ ••• minute globules, closely resembling those of mercury (fig. 9\ 9 15) ; but when air is present in such quantity as to oxidize part of the vapour, the globules of metal are blended with the white powder or transparent crystals of arsenious acid.* ARSEXious ACID (Oxide of Arsenic, Sesquioxide of Arsenic, White Oxide of Arsenic, White Arsenic, Arsenic'\). In the two years 1837 and 1838, arsenious acid was the ascertained cause of 185 deaths, being as many as those attributed to all the pre- parations of opium, and considerably more than those caused by all the other poisons. Of these 185 deaths, 112 were ascertained to have been suicidal, 21 accidental, and 12 homicidal ; but the homicidal deaths from this cause were probably much more numerous. Since the act of 1851 (14 Vict., cap. xiii.), which restricted the sale of arsenic, and prescribed its admixture with soot or indigo when sold in small quantities, it is probable that cases of poisoning by arsenious acid have become less numerous, both absolutely and re- latively to other poisons. In the two years 1837, 1838, it was, as has just been stated, the cause of 185 deaths. This was out of a total for those years of 543 deaths by poison. But in the five years 1852- 56, it gave rise to 27 only of the annual average of 268 deaths by ascertained poisons. In the first period, therefore, the proportion was 1 in 3, or 34 per cent., in the second period 1 in 10, or 10 per cent. In France arsenious acid takes still higher rank as a poison. The common use of arsenious acid as a poison will excite no sur- prise when it is borne in mind that it is as white as flour, that it is tasteless or nearly so, that it may be mixed with articles of food without undergoing or causing any change, that it is very cheap, and that it is in common use, as has just been stated, for a great variety of purposes. Arsenious acid is found in commerce as a solid cake, and as a white powder. The cake, when first sublimed, is nearly transparent, but * Refer to a paper by the author, ' On the Production and Identification of Crystals of Arsenious Acid and Crusts of Metallic Arsenic,' in Dr. Beale's ' Archives of Medicine,' No. Ill, 1858. t In some country places it is known as " Mercury " ! 2 B 370 ARSENIC AND ITS PREPARATIONS. becomes opaque by keeping, and resembles white enamel, interspersed with thin transparent striaj. It is the powder which is ordinai-ily used as a poison. Arsenious acid, in either of these forms, has well-marked physical properties, and may be readily identified by chemicjil tests. Properties. — I. Arsenious acid is sparingly soluble in water, hot or cold. 2. The solution has a very slight acid reaction. 3. In substance it is tasteless, but its solution or vapour has a very faint sweet taste. 4, The solution of the acid in boiling water, when slowly evaporated, deposits well-formed octahedral crystals. 5. It is very soluble in ammonia, in hydrochloric acid, and in carbonate of potash ; and it is deposited; from its solutions in ammonia and hydro- chloric acid, also as octahedra. 6. It combines with alkalis, forming soluble arsenites. Two of these properties, the solubility and the taste, require to be more minutely examined. Solubility of Arsenious Acid. — Cold water dissolves from half a grain to a grain to the ounce; boiling water poured on the poison re- tains on cooling one grain and a quarter to the ounce ; and water boiled for an hour on the powder retains on cooling 12 grains to the ounce. But the presence of organic matter renders the poison less soluble. (Taylor.) Taste of Arsenious Acid. — The poison was formerly described as having an acrid taste, but this statement is now acknowledged to be incorrect. The powder has scarcely any taste ; if any, a very faint sweet taste. This sweetness is more perceptible in solution, and still more so in vapour.* Tests. — We may have to identify arsenious acid, 1. In substance 2. In solution. 3. In organic liquids; and, 4. In the fluids and solids of the body. 1. Arsenious Acid in Substance. a. When heated by the spirit lamp on platinum foil, it sublimes unchanged, as a white vapour, b. When heated in a reduction-tube, it is deposited either as an amorphous powder or as octahedral crystals. c. When moistened by liquor potassas it undergoes no change of colour, d. When moistened by sulphide of ammonium, no immediate change of colour takes place ; but, after a time, when the excess of ammonia has evaporated, a canary-yellow sulphide of arsenic is formed. This change may be brought about directly by heat, or by the addition of acetic acid. e. When the arsenious acid is mixed with charcoal and heated, the metal is reduced and volatilized ; and if a reduction-tube be employed for this * Otto Tachenius, in his Hippocrates Chemicus, says, " that after many sub- limations of arsenic, on opening the vessel, he suclicd in so grateful and sweet a vapour, that he greatly admired it, having never experienced the like before." See Baker's ' Employment for the Microscope,' p. 133. The tastelessness of the powder is proved by the case of a lad who took from the mouth of a bottle as much arsenious acid as would cover a sixpence, and who told me that it tasted like flour. AR8ENI0US ACID. SUBLIMATION. 371 Fig, 16. purpose, the metal is deposited on the cooled sides of the tube as a shining metallic crust. /. The vapour has the characteristic garlic odour. Of these tests there are two which require to be more exactly de- scribed, and their results more minutely examined. These are the test of sublimation and the test of reduction. Sublimation. — It has just been stated that arsenious acid, when heated by the flame of a spirit-lamp in a glass tube, is converted into a white vapour ; and that this vapour is deposited on the sides of the tube either as an amorphous powder, or as octahedral crystals. But as it is the crystals which are characteristic of the poison, and not the white amorphous deposit, it is necessary to explain by what mode of manipulation the crystalline deposit may be obtained. Now experience has proved that in order to the development of characteristic crystals of arsenious acid the white vapour must be raceived on a heated surface. On a cool surface it deposits itself as an amorphous powder. The process of sublimation is usually performed in a reduction-tube of green glass of about the size and length shown in fig. 16, After drying the tube by passing it repeatedly through the flame of the spirit- lamp, the arsenious acid is to be conducted to the sealed end through a smaller glass tube, or by means of a gutter of paper, so as to avoid soiling the sides of the tube. The middle portion of the tube should then be heated and the flame of the lamp immediately transferred to the sealed end. The vapours as they rise will be deposited on the heated part of the tube as crystals, and on the cooler portion of the tube as an amorphous powder. One object contemplated by the pro- cess just described is so to intro- duce the arsenious acid as to keep the sides of the tube clean. For this pur- pose, as well as for obtaining well- formed crystals, the following modified process is to be commended : — Take two small tubes of glass (green or white), of which the one shall be large enough to inclose the other. Shape the larger into the reduction-tube, fig. 16, and the smaller into the shorter tube, shown in the same figure. Introduce the arsenious acid into the short tube, and drop it into the reduction-tube. Apply the flame of the spirit-lamp so as to envelope the lower third of the tube. By the time that the temperature of the inner tube is so raised as to sublime its contents, that of the outer tube will be favouiable to the deposit of the vapour in the form of distinct crystals. 372- ARSENIC AND ITS PREPARATIONS. Fig. 17. This method of sublimation, in common with all similar methods, is open to the serious objection that the crystals cannot be conveniently examined through the thick round sides of the tube by means of the lens or microscope ; and this objection applies with great force to minute crystals obtained from small quantities of the poison. To obviate this objection I have proposed the following method : — Take a small, clean, dry specimen-tube, a, of white glass, of about twice the length and size shown in fig. 17, drop it into a hole in a slab of porcelain or brass, b, and hold it in a verti- cal position. Let the arsenious acid fall to the bottom of the tube. Then hold a disc, c, of thin crown glass of the size of a crown-piece in the flame of the spirit-lamp till it is quite dry and hot : place it at once over the mouth of the tube, and imme- diately apply the point of the flame of the lamp steadily to the bottom of the tube, till the lower surface of the glass disc is covered with glittering crystals. As soon as the crystals are seen to form on the disc, withdraw the lamp. Repeat the operation with other discs. By this method crystals may be obtained from the smallest visible speck of arsenious acid, and, being upon a flat surface, may be con- veniently examined by the lens or microscope. Excellent results of extreme delicacy may also be obtained by a similar method 'of pro- cedure presently to be described. (See flg. 33.) The crystals of arsenious acid obtained by these methods of subli- mation are also procured by oxidation of the metal arsenic, as a constituent part of tests yet to be described ; and as the crystals, how- ever procured, always furnish a very important means of identification, their shape and characteristic properties ought to be well understood. Crystals of Arsenious Acid. — These crystals are remarkable for their brilliancy and permanence. ^'^- ^^- ^'g- 19- They are distinct and sepa- rate, except when superim- posed, very rarely foi-ming compound crystals of any definite shape. Their pre- vailing form is the regular oc- tahedron, consisting of eight equilateral triangles joined at their edges. A section passing through four and dividing the cryst:il into two equal parts gives a figure which is a perfect square. The crystal is shown in outline in fig. 18, and as it is occasionally seen under the microscope in fig. 19. But in every con- siderable group of crystals there are many modified and imperfectly- THE CRYSTALS OF AESENIOUS ACID. 373 formed octahedra, together with some prismatic and other forms, con- cerning which it is necessary to give a few words of explanation. The regular octahedron, it should be understood, presents itself to the lens and microscope under many different aspects, according as the crystal adheres by an angle, face, or edge, and according as the light traverses the crystal or is reflected from it. When the crystals are viewed by reflected light, or when the light passes through them so as to render them practically opaque, they present either two, three, or four sides, as in the annexed engraving (fig. 20), in which 1 repre- sents a crystal resting on a face with an angle of the face pointing for- ward ; 2, a crystal also resting on a face, but with the base of the triangle forward ; 3, a crystal placed as 1, but differently viewed, and 4, a crystal attached by an angle, and with the opposite angle pro- jecting forward. Fig. 20, But when the light is transmitted through the crystals these forms are modified and disguised by such shadows as those shown in fig. 21. Fig. 21. These shadows represent the remote inclined sides of the crystal, so that crystal 3 of the series displays four sides, crystal 6 five sides, and crystal 5 seven sides. It very rarely happens that the eight sides of the crystals are distinctly visible, as in fig. 19, in which the two equilateral tiiangles represent the parallel sides without shadow, and the three receding triangles and three dark triangular shadows com- plete the number. Sometifnes, in consequence of the indistinctness of the shadows of the receding sides, the crystal is seen as in 1, fig. 2.5, under the simple form of an equilateral triangle. Sometimes the octahedron, instead of being moulded on a square, is built upon an oblong, so as to assume the form shown in fig. 22. In all groups of well-developed crystals most of the forms just described and figured will be readily seen ; but it should be understood, as has just been stated, that the octahedron is not always perfect. The opposite angles Fig. 22. 374 ARSENIC AND ITS PREPARATIONS. are ofteu truncated, as in No. 4, fig. 21 ; sometimes one angle only ; sometimes all the angles. Again, the sides of the crystals are sometimes indented, and the angles rounded, as in fig. 23, Fig. 23. so as to resemble a trefoil, and the crystal is sometimes Vfi.\ed in such a position (2, fig. 21) as to be identified with difficulty. Sometimes, too, the crystals are not only truncated or disguised by curtailment of their angles, sides, or edges, but they are imperfectly built up, so as to present several forms different from any of those figured above, but of very common occurrence in all groups of crystals. One of the most common of these forms is a black square without any perceptible markings, which would result from a half crystal attached by an angle, or possibly from 4, fig. 20. Five or six other forms frequently met with would result from a half crystal divided by a plane parallel to two of its faces, as in fig. 24. This half crystal yields the forms depicted in fig. 25, namely, 1, a simple equilateral triangle ; 2, an equilateral triangle resting on half the adjoining triangle, as a base ; 3, a simple hexagon ; 4, a hexagon with thi-ee small equilateral triangles in shadow; 5, a truncated equilateral triangle; 6, a figure having the appearance of a triangular prism. Fig. 25. Fig. 24. The twin crystals or macles (fig. 26) resulting from the juxta- position of corresponding portions of the half ciystal, shown Fig. 26. in 6, fig. 25, are also not uncommonj and it is not unusual ^xTn. for these twin crystals to assume forms very easily mis- \^ ^y\ taken for cubes. In one instance I have seen the crystals built, up into a rectangular prism, with the ends shaped into a short four- sided pyramid, and the length divided into two unequal parts by a line at right angles to the axis. Sometimes when the heat of the surface on which the crystals are deposited is insufficient, all the crystals assume irregular and confused forms.* * Those who desire fully to understand, or clearly to explain, the microscopic appearances of the crystals of arsenious acid should study those appearances on the larger scale by means of octahedra of wood and glass, referring at the same time to the • Mineralogy and Crystallography ' of Tennant and Mitchell. ARSENIOUS ACID. REDUCTION. 375 Some of the many forms assumed by the crystals of arsenious acid, Fig. 27. as seen under the microscope by transmitted light, are shown in fig. 27, as well as in fig. 13, where they are mixed with scattered globules of metallic arsenic ; also in figures 29 and 30, where they are viewed by re- flected light in mixed crusts of arsenious acid and metallic arsenic. Reduction. — This process is commonly eflfected in the tube of green glass repre- sented in fig. 28. The arsenious acid, well mixed with about four times its bulk of finely powdered recently ignited charcoal, is introduced into the tube at a, with the precautions just described in speaking of the process of sublimation, with this difference only, that Fig. 28. it is not necessary to heat the middle portion of the tube. On applying the heat of the spirit- lamp steadily to the sealed end of the tube held at an angle of 45°, the metal rises in vapour, with the odour of garlic, and is deposited on the sides of the tube from a quaiter to half an inch above the mixture, as a dark brown or black ring, h. As the vapour of the metal rapidly attracts oxygen fiom the atmosphere, it is readily reconverted into arsenious acid. Hence the ring is always a mixture, in variable pro- portions, of metallic arsenic and aisenious acid. The lower portion of the ring consists chiefly of metal, and has the appearance of a mirror; the portion immediately above it contains a larger admixture of arsenious acid, and the highest portion may consist almost wholly of the acid. By cautiously applying the flame of the lamp to the lower portion cf the ring, it may be rendered more compact and more distinctly metallic ; and by driving the crust repeatedly up and down the tube, it may ba wholly converted into arsenious acid, in the form of octahedral crystals. When this process of reduction is performed with proper precautions (using a tube of green or German glass that the glimmer of lead reduced in the glass itself may not be confounded with the crust of metal ;* taking care that the mixture of arsenious acid and charcoal and the sealed end of the tube itself are free from moisture, so that the mixture may not be driven up into the tube ; taking equal care to * The objection formerly advanced that the arsenious acid sometimes used in the manufacture of glass might be reduced, so as to create a glimmer in the glass, is now abandoned. 376 ARSENIC AND ITS PREPARATIONS. introduce the mixture so as not to soil the tube ; and drying the tube itself after its introduction) very satisfactory results are obtained. The mixed crust thus procured cannot be mistaken for globules of mercury ; nor can it be confounded with the crust obtained by the same process from the white hydrated oxide of cadmium, as the anhydrous oxide of cadmium blended with the crust has a brown, green, or yellow colour. But as it may always be alleged that the metallic crust obtained by this process of reduction does not present of itself such distinct cha- racters as to justify a witness in affirming that it is due to arsenic and to nothing else, it is always deemed necessary to submit the crust to further manipulation. This is done in one of two ways. The sealed end of the tube containing the residue of the charcoal is drawn off, and the metallic crust driven up and down the tube till the metal is changed into the oxide, and deposited as octahedral crystals on the side of the tube ; or the sealed end of the tube, as well as the part of it containing no deposit, are filed off, and the part containing the crust being folded in paper, is broken into small fragments, which fragments are introduced with like precautions into a second reduction-tube, and the metal con- verted into arsenious acid by heat. In either of these ways the evidence afforded by the reduction of the metal is confirmed by the production of the characteristic crystals of arsenious acid. But this method of procuring crusts of metallic arsenic from arsenious acid and charcoal, and crystals of arsenious acid from the metal, is open to two classes of objections. The method itself is want- ing in delicacy, and encumbered by many precautions, and the results present themselves in a form so unfavourable for examination that the .more minute crusts and crystals cannot be identified with certainty. The use of the lens and microscope is in all cases rendered difficult, in some impossible. These consideiations have led me to recommend the same simple apparatus for the reduction of the metal as that already described for the sublimation of the oxide, and shown in fig. 17. The mixture of arsenious acid and charcoal is first dropped into the clean and dry specimen-tube (a) ; ' the disc of glass (c) is then held in the flame of the spirit-lamp till the moisture is driven off, and when cool is placed over the mouth of the tube. The point of the flame is then steadily applied to the bottom of the tube. The vapours of the metal when first disengaged from the mixture combine with the oxygen of the air contained in the tube, and arsenious acid is re-formed, which deposits itself on the under surface of the glass disc, as an amorphous powder, or in glittering crystals, according to the temperature. The after-deposit is in the metallic form. The crust in this case, then, as in the usual process of reduction, is a mixed crust of metallic arsenic and arsenious acid. This crust, when examined by the lens, or under the microscope by reflected light, has the appearance shown in fig. 29, where the sparkling triangular facettes of the octahedral crystals of arsenious acid are shown project- ing through a layer of metal ; or that depicted in fig. 30, where the MIXED CEUSTS OF ARSENIC AND ARSENIOUS ACID. 377 distinct octahedral crystals or masses of crystals are more or less thickly coated and obscured by a light brown or giay mefcillic deposit. Fig. 20. FiK 30 A third form assumed by some of the thumei crusts, md b} the cir- cumference of the thicker crusts, consists of cr^stds of arsenious acid interspersed with distinct globules of metallic arsenic, as in fig. 31. The thinnest crusts of all present an iridescent appearance, and may be resolved, under the higher powers of the microscope, into aggregates of small globules. Crusts of pure unmixed metal, presenting under the microscope the appearances shown in fig. 32, may be readily ob- Fig. 31. Fig. 32. tained by covering the mixture of arsenious acid and charcoal with a layer of dried bicarbonate of soda, so as to fill the tube with an atmo- sphere of carbonic acid gas. See also fig. 15, p. 369. The appearances presented by figures 29, 30, and 31, are quite decisive of the presence of arsenic. Those presented by the unmixed metal in fig. 32 are less conclusive, as the globules sometimes are not to be dis- tinguished by their appearance from those of mercury. Hence it may be necessary in the case of the purer crusts of arsenic, and expedient in other cases, to confirm the evidence afforded by the microscopic characters of the metallic or mixed crust, by converting the metal into arsenious acid. With this view the portion of the glass bearing the crust must be cut into narrow slips with a writing diamond. The slips must then be introduced into a specimen-tube (fig. 17), and treated in the manner just described. The glass disc will be covered with glittering crystals. 378 ARSENIC AND ITS PREPARATIONS. or with a mist which can be resolved, under the higher powers of the microscope, into gi-oups of well-formed octahedra. It may be well to state that the metals cadmium, selenium, and tellurium are, like the metal arsenic, sublimed by the heat of a spirit- lamp; that selenium is also deposited as globules, and tellurium some- times converted into crystle salt of lead are a burning and pricking pain in the throat and gullet, thirst, vomiting, colic pains, with tenderness of the belly, obstinate con- stipation, cramps in the extremities, cold sweats, and, in fatal cases, convulsions, and tetanic spasms. In one recorded cas^ the pulse fell to 40. The most important and interesting form of lead poisoning is that which is induced slowly by the long-contixlued use of preparations of 424 LEAD AND ITS PREPARATIONS. lead, whether as medicine, in the arts, or in consequence of the acci- dental impregnation of water or articles of food. The form in which the effects of the poison first show themselves is that of the painters' colic ; its more remote effects are known as the lead pais)', IVie Painters' Colic, or, as it is called from the place where it was first observed, Colica Pictonum, is marked by excruciating pain of the abdomen, especially in the pit of the stomach and around the navel. This pain is almost always relieved by pressui-e. The belly is hard, the muscles of the abdomen strongly contracted, and the navel drawn inwards. The bowels are either obstinately confiueil or scanty motions are passed with much suffering. Very rarely diarrhoea is present. The urine is small in quantity, and passed with difficulty. The countenance is dull and anxious, the skin bedewed with cold per- spiration, the pulse commonly of the natural fiequency, but sometimes accelerated, the breathing quick and catching. In rare instances febrile symptoms are present. The painters' colic sometimes comes on without previous symptoms of disease, at others after long-continued indigestion and disorder of the bowels. It may terminate either in complete recovery, or may pass into the second form of chronic poisoning — lead palsy. In rare in- stances it terminates in a species of apoplexy, which comes on with giddiness, extreme weakness, and toi-por. As these symptoms increase, the pains in the belly subside, and the patient at length dies convulsed and comatose. Lead Palsy. — This is sometimes the termination of a single attack of colic, but more commonly it supervenes after repeated seizures. In some cases, again, it comes on without any previous attacks of colic. The disease chiefly affects the upper extrerriities, especially the muscles of the hand and forearm, which Hrst lose their power and then gradu- ally waste away. The loss of power is chiefly in the extensor muscles, so that when the arm is raised, the hand falls by its own weight. Hence the expression, ' dropped hand.' The patient generally raises one hand by the aid of the opposite arm, which is very characteristic of the loss of power in the muscles of the forearm and hand. This affection is in all cases difficult of cure, and very apt to recur on the renewed application of its cause. The persons most subject to the action of lead are those employed at furnaces for smelting lead ore, manufacturers of litharge, and of red and white lead, house-painters, colour-makers, plumbers and workers in lead, glass-blowers, glaziers, potters, and manufacturers of glazed cards. It occurs occasionally in persons who make comparatively little use of lead, as in compositors from the handling of the types, in fishmongers from the use of lead counters covered with brine.* In other cases, where it cannot be traced to the use of lead in any way, it is attributable to the drinking of water contained in leaden pipes or cisterns, under the circumstances presently to be mentioned. * I have witnessed two or three cases among this class of tradesmen. TEEATMENT. 425 In the course of the several employments just mentioned, lead finds its way into the system either by the skin, the lungs, or the stomach. The" chief practical rule for the prevention of disease consists in the strict enforcement of cleanliness. A great amount of disease has been prevented by the substitution of moist for dry grinding. Animals are frequently poisoned by lead contained in the water they drink, and sometimes by the use of utensils containing some preparation of lead. There is one symptom which has been pointed out as characteristic of the action of lead on the system ; viz., a blue line on the gums round the margin of the teeth. This is a valuable indication, and one rarely absent where marked symptoms of lead poisoning are present. It exists in many cases where it is not possible to prove the intro- duction of lead into the system, and when it is necessary to assume that it finds its way into the body through the water which the patient drinks. Fost-rnortem Appearances. — In one case of acute poisoning by Goulard's extract, the morbid appearances were the following: — The lower end of the gullet, the whole stomach and duodenum, a part of the jejunum, and the ascending and transverse colon were greatly inflamed, and the villous coat of the stomach appeared as if it had been macerated. The stomach contained six ounces of a reddish- brown fluid which had a sweetish, styptic, metallic taste, exhaled the odour of vinegar while evaporating, and yielded globules of lead when the dry residue was subjected to the process of reduction. (Christison.) In colica pictonum there are no constant morbid appearances beyond an unusual constriction of the large intestines. In lead palsy the aftected muscles are found pale and flaccid, and when the disease has been of long continuance they resemble white fibrous tissue. Treatment. — The antidotes to the salts of lead are the soluble alkaline or earthy sulphates — the sulphates of soda or magnesia. These should be freely administered, dissolved, or suspended in water. If vomiting is absent, it may be excited by emetics of sulphate of zinc, and encouraged by copious draughts of warm water, or the stomach-pump may be used. Milk and white of eggs may be given with advantage. When the colic pains are severe, and the bowels costive, opium may be administered in combination with aperients, and copious injections of warm water may be given. The remainder of the treatment is that proper to the irritant poisons. In consequence of the extensive use of lead in pipes and cisterns for conveying and holding water, and the ill effects which sometimes re- sult from the action of the water upon it, it is important to examine the circumstances under which that action takes place. This subject has been carefully examined by Drs. Christison, Taylor, and Miller. The principal results of their inquiries may be briefly stated as follows : — The contact of air and water with the metal leads to the formation of an oxide of lead, which is dissolved in the water. The solution 426 LEAD AND ITS PREPARATIONS. absorbs carbonic acid from the air, and the resulting oxycarbonate is deposited in silky scales. A fresh portion of oxide is formed and dis- solved and a fresh crop of crystals deposited ; and in this way the metal is rapidly corroded. The free access of atmospheric air is essential to these changes, for distilled water deprived of its gases by boiling, and excluded from the air, has no action on lead. The action of air and water on lead is very rapid when the water is pure. Thus distilled water, or very soft water, or rain water collected in the open country left in contact with pure lead, with the free access of air, cause a very rapid corrosion of the metal ; but the rain water collected from the roofs of houses in large towns, in consequence of the impurities which it dissolves, has little or no action on lead. On the other hand, the action of water on lead is materially modified by the presence of various saline substances, even in the small quantity of three or four grains to the gallon. The chlorides and nitrates increase the corrosion ; but the sulphates, phosphates, and carbonates lessen it. Bicarbonate of lime is a very effectual preser- vative, and to the presence of this substance many springs owe their property of not acting on lead. Sulphate of lime also affords a very complete protection, so small a quantity as one part in 5000 effectually preventing the foranation of the carbonate. Some kinds of river water, as that of the Thames and the water used in Edinburgh, contain saline matters in sufficient proportion to render the use of lead perfectly safe. The same remark applies to most spring waters. But the waters of some rivers and springs are so destitute of saline matters as to act powerfully on lead. It must, moreover, never be forgotten that carbonic acid, if present in the water, will completely counteract the preservative effect of the salts above mentioned. It is better, therefore, to forego the use of lead for cisterns and water-pipes. Slate should be used for cisterns, and iron, earthenware, or glass for pipes. It may be stated, then, as a general result, that the action of water on lead, and the consequent danger of conveying and preserving it in pipes or cisterns made of that material varies directly as the purity of the water. It follows that we may render the use of lead for such purposes perfectly safe by the artificial admixture of saline matter with the purer kinds of water. Sulphuric acid by forming an inso- luble sulphate of lead is also an efficient protection. The use of lead is attended with most danger when it is employed to collect or pre- serve rain or snow-water, or spring water of unusual purity ; and the danger is increased by the use of leaden lids to cisterns, the pure water rising by a natural process of distillation, and collecting on the lid. There is one cause which greatly facilitates the action of water on lead, and which may act with sufficient energy to neutralize the pre- servative effects of saline matter, and be even increased by its presence, namely, the galvanic action excited by the contact of some other metal with the lead, or of the solder used for joining the sheets of lead. The vegetable acids and fatty substances have the property of dis- COPPER AND ITS PREPARATIONS. 427 solving lead ; hence the danger of keeping asceseent fruits, or liquors, or fatty matter, in vessels made of that material, or glazed with the oxide. Sour milk, cider, wine, and rum, have obtained poisonous properties in this way. Shot used for cleaning wine-bottles, and then carelessly left in them, have impregnated the wine with lead. The treatment which seems best suited to promote the elimination of lead from the system consists in the administration of iodide of potassium in doses of five or of ten grains three times a day. 5. COPPER AND IIS PREPARATIONS Poisoning with the salts of copper is of very rare occurrence. Among the 543 cases of poisoning occurring in England and Wales in 1837-8, not one was due to this caui-e, nor is the poison specified in the Registrar-General's list of the causes of violent death in the five years 1852-56. In consequence of the marked colour of all the salts of copper, they are not likely to be taken accidentally, and they are ill adapted to the purposes of the murderer. They are, however, occasionally used by the suicide. The use of copper utensils in cookery sometimes leads to the accidental admixture of poisonous salts of copper with food ; and the sulphate of copper has been improperly employed to promote the fermentation of dough, to decolourize sugar, and to give a green colour to pickles. The arsenite or aceto-arsenite of copper is also largely used in the arts. See Arsenic (p. 397). Metallic copper is not poisonous ; but in consequence of the readi- ness with which it oxidates and combines with acids, it cannot be swallowed with impunity. Very injurious consequences have been known to be produced by sucking copper coin ; and in a state of minute division, as used in the process of printing, it appears to act as a poison. Copper in the form of hydrated oxide, and in combination with acids, is in common use in the arts. It will be necessary to particularize the following : the hydrated peroxide, the carbonate, the sulphate, and the acetates. The Hydrated Peroxide. — Copper exists in this shape under the names of mineral green and verditer. Mineral green formerly con- sisted of arsenite of copper, but is now formed by a combination of the hydrated peroxide with pure lime or chalk, potash, and alumina. Verditer consists of the same materials in a different proportion. The anhydrous peroxide of copper is a brownish black powder, which is readily dissolved by nitric acid, the solution assuming, on the addition of ammonia in excess, a deep blue colour. The hydrated peroxide of copper may be procured by adding liquor potassae to a so- lution of any of the soluble salts of the metal. As none of the salts of copper assume the importance of arsenious acid or corrosive sublimate, it will suffice to consider the tests for copper generally, and then to describe and distinguish from each other those salts which are in common use. Tests for the Salts of Copper. — All the salts of copper are either 428 COPPEIl AND ITS PREPARATIONS. blue or green. Their colour, therefore, distinguishes them at once from most other substances. The salts of nickel and the sulphate of iron are also green, but the distinction between the green sails of copper and these substances will be readily made by comparing them in a state of solution. In very dilute solutions the colour of the salts of copper disappears, or is so masked as to afford no clue to the nature of the substance with which we have to deal : it will be necessary, therefore, to suppose that substance to be unknown to us. Acting on this supposition, we first test the liquid with sul- phuietted hydrogen, when we obtain a deep brown or blatk pre- cipitate. Sulphide of ammonium yields the same precipitate. On the addition of liquor ammonia; the hydrated pei oxide is first thrown down ; and this being dissolved, by the addition of ammonia in excess, the chai'actftristic deep blue coloured solution of the hydrated per- oxide is formed. The salts of copper in solution may be further identified by the following tests: 1. FeiTocyanide of potassium yields a fine hair-brown gelatinous precipitate ; 2. Polished iron (a knife or a needle suspended by a thread) placed in a solution of a salt of copper is speedily coated with a thin film of the metal ; 3. A drop of the solution placed on platinum foil, and slightly acidulated, when touched with a strip of zinc, yields a similar metallic deposit ; 4. If a minute fragment of zinc is placed in a drop of a solution of a salt of copper on a fiat surface of glass, the copper is deposited in an arborescent form ; and is sufficiently distinguished from other metals by its colour. Some of the salts of copper possess peculiar properties, and may have to be distinguished from each other. Carbonate of Copper (natural verdigris). — This is the gi'eenish coating formed on the surface of copper and its alloys by the action of air and water. It is readily distinguished from the other salts of copper by effervescing with acids. The reactions of the base are those of other salts of copper. Sulphate of Copper (blue vitriol, blue-stone, Roman vitriol). — The base is detected by the tests already described. The salt is further known by adding a few drops of liquor ammonias, and a solution of arsenious acid. Green arsenite of copper is thrown down. The sul- phuric acid in combination may be detected by the test of nitric acid and nitrate of baryta. Subacetate of Copper (artificial verdigris). — The term artificial ver- digris is sometimes applied to the unmixed subacetate, and sometimes to a combination of this with the neutral acetate and carbonate. Its colour accordingly varies, being sometimes blue and sometimes green. The subacetate is known by the effect of heat. When introduced into a test tube, and heated by the flame of a spirit lamp, a jiortion of acetic acid is given off; and another part being decomposed, leaves an ash of carbon, which deoxidizes the copper, so that a thin film of metal is left on the sides of the tube. COPPER IN ORGANIC LIQUIDS. 429 Acetic acid is also given off on boiling the salt with dilute sulphuric acid. Nitrate of Copper. — This is in the form of deliquescent blue crystals. The acid in combination may be detected by the absence of a precipitate with nitrate of baryta, and with nitrate of silver ; and by the ruddy furaes of nitrous acid gas evolved by boiling the crystals with tin filings in a few drops of distilled water. By adding liquor potassai to the solution, nitrate of potash is formed, which may be identified by appropriate tests (p. 333). Chloride of Copper. — There is a soluble chloride, and an insoluble subchloride of copper. The chloride is of a bright-green colour, the subchloride is white. An oxychloride is known in the shops as Brunswick Green. The chloride is deliquescent and very soluble in v/ater ; the sub- chloride is insoluble in water, but soluble in acids. The tests for the base are the same as for other salts of copper. The hydrochloric acid in combination may be detected, in the case of the soluble chloride, by the addition of nitrate of silver. The insoluble subchloride must be convei-ted into a soluble salt for the purposes of examination. Arsenite of Copper. — See the chapter on Arsenic (p. 397). The several salts of copper are found in the shops, mixed in various proportions and under different names, as pigments. Copper in Organic Liquids. — Solutions of copper are decomposed by several of the common contents of the stomach, — such as albumen, fibrin, milk, tea, coffee, &c., and by the mucous membrane of the stomach, the suboxide being thrown down. As the salt of copper is not always completely decomposed, it may often be obtained in sufficient quantity for analysis by simply boiling with distilled water and passing the solution through a filter. The insoluble substances must be reserved for further examination. The clear liquid which has passed the filter may be tested by the reagents just described. By slightly acidulating the liquid, and then passing through it a stream of sulphuretted hydro- gen, the brownish-black sulphuret of copper is thrown down. This must be carefully collected, and washed, and incinerated in a glass tube. It is thus freed from any adhering organic matter. The sul- phuret may now be converted into sulphate by treating it with a few drops of nitric acid. The solution will strike the usual deep blue' colour with an excess of ammonia. If copi^^)er is not by this means detected in the liquid which has passed the filter, the insoluble substances which remain on the filter, or ate contained in the stomach, must be dried and heated to redness in a crucible, till they ai'e completely charred. The residue contains metallic copper, and must be gently heated in equal parts of nitric acid and water. Nitrate of copper is thus formed, which may be identified by the usual tests. Copper has been detected in the solid organs of the body, but more rarely in the secretions, in cases of poisoning by its salts. 430 COPPER AND ITS PREPARATIONS. Copper has also been found in several vegetable substances used as food, and is asserted to exist as a natural constituent of the fluids and solids of the human body. The existence of copper in vegetable sub- stances has been confiiTned and explained by M. Boutigny, who has traced it to the manure used in laising those substances. Its presence as a natural constituent of the human body, has, however, been rendered doubtful by the negative results of experiments pei'formed by Chiistison and Chevreul. The quantity of copper existing naturally in animal and vegetable substances is so minute, not exceeding in any case one part in 120,000, and in some instances being so little as one in 1,500,000 parts, that it can give rise to no fallacy even where large portions of the solid contents of the stomach or of the body itself are submitted to analysis. Quantitative Analysis. — Use for this purpose the precipitated sul- phuret, digest it in nitric acid, and preci}>itate the oxide from the solution by potash. One hundred parts ot the black oxide correspond to 312 of the crystallized sulphate. SYMPTOMS, POST-MORTEM APPEARANCES, AND TREATMENT. Symptoms. — The symptoms set in from a quarter to half an hour after swallowing the poison, with pains in the abdomen resembling colic, with nausea, eructations, vomiting of matters of a bluish oi- gieen colour, purging and cramps in. the extremities. Kervous symptoms also supervene. Convulsions, palsy of the limbs, tetanus, and insensi- bility have been present in dilierent cases. As in the case of arsenic and mercury, the group of symptoms varies in each instance. One symptom of more frequent occurience in poisoning with the salts of copper than in poisoning with other irritants is jaundice. Post-mortem Appearances. — The mucous membrane of the stomach and intestines has been found inflamed, ulcerated, thickened, and of a green colour, and in parts apparently gangrenous. The salt of copper sometimes adheres to the surface of the membrane. The in- flammation and discolouration of the mucous membrane occasionally extend to the oesophagus. The skin is yellow. The other post-mortem appearances are not characteristic. in some instances the intestines have been found perforated. Treatment. — The antidotes to the salts of copper are albumen, and iron filings. The first is to be prefened. The treatment will consist in the free administration of the white of egg, followed by mucilaginous drinks. If vomiting is not present the sltomach-pump may be used. The remainder of the treatment will vary with the symptoms. Severe efl'ects have been produced by comparatively small doses of the salts of copper. In a case mentioned by Dr. Percival, convulsions were occasioned by two drachms of blue vitriol. Shortest Fatal Period. — The salts of copper have proved speedilv fatal. A girl aged sixteen months died mfour hours after swallowing ACCIDENTAL POISONINGS BY COPPER. 431 several fragments of blue stone (Taylor). In other instances death has taken place after longer intervals, such as 12, 13, 60, 72, and 78 hours. Accidental Poisoning by Copper. — Serious and even fatal accidents have occurred from the use of copper vessels in cooking. The inmates of a monastery suffered severely from obstinate and severe colic, retching, and bilious vomiting, costiveness, flatus, burning pain in the pit of the stomach, in the kidneys and extremities, and para- lytic weakness in the arms. These symptoms were traced by Gmelin to the fact, " that every vessel in the kitchen, the pots and pans, and even the milk pails and butter dishes for storing the butter, were made of copper." The principal facts established in reference to the impregnation of various fluids and articles of food with copper, in consequence of being prepared or kept in copper vessels, are the following. Distilled water kept in contact with clean copper is not impregnated with it. Solu- tions of several saline matters, as common salt, alum, nitre, and Epsom salts, when heated in copper vessels, are found to contain the poison. Acids, and fatty and oily matters, especially when rancid, act still more strongly on copper vessels. One general principle applies to all these substances, which is, that provided the vessels be clean, they may be boiled in them with comparative safety, but cannot be allowed to stand in them without danger. The contact of air with the moistened copper leads to the formation of the hydrated carbonate, which is dis- solved by any acid that the substance may happen to contain. As saline, acid, or oily matters act strongly on copper vessels, it would be well to avoid using such vessels in preparing articles of food containing any of these matters. 6. ZINC, TIN, SILVER, IRON, BISMUTH, CHROME, AND THEIR PREPARATIONS. There are two preparations of zinc which require notice — the sulphate and the chloride. Zing (sulphate of zinc, white vitriol, white copperas). — This sub- stance is in common use as an emetic, but as a poison it is unimportant. Sulphate of zinc is found in the form of colourless, or nearly colour- less, prismatic crystals, of a styptic taste, and very soluble in water. It resembles oxalic acid and sulj)hate of magnesia. From the former, it is distinguished by the tests described at p. 345, and from the latter by adding to their respe(;tive solutions sulphuretted hydrogen or sulphide of ammonium. The sulphate of zinc yields a white precipitate, but there is no precipitate with the sulphate of magnesia. Sulphate of zinc in solution possesses the following properties: 1. It is precipitated as a white sulphuret, by sulphuretted hydrogen and sulphide of ammonium, provided the solution does not contain an excess of acid. 2. Liquor ammonise and the sesquicarbonate of am- monia throw down a white precipitate soluble in an excess of the precipitant, 3. Ferrocyanide of potassium causes a white precipitate. 432 ZINC, TIN, ETC., AND THEIR PREPARATIONS. As sulphate of zinc often contains iron, the precipitates are apt to be tinged with the colours which ifon gives witli these reagents. In Organic Liquids. — Sulphate of zinc is decomposed by albumen and milk, which form with the oxide an insoluble compound, and also by substances containing tannin. The first step of the piocess for organic liquids consists in acidulating with acetic acid, by which any oxide thrown down in union with animal matters is dissolved. The mixture must then be filtered, and sulphide of ammonium added. A white sulphuret of zinc is thrown down, which must be washed, collected, dried, and heated to redness in a glass tube. The residue is then to be acted on by strong nitric acid, which dissolves the zinc ; and the acid solution, being neutralized by caibonate of ammonia, is ready for the application of the tests. The carbonate of zinc which results from this decomposition becomes yellow when heated, and resumes its white colour on cooling. It is also redissolved by an excess of the car- bonate of ammonia. Symptoms. — Sulphate of zinc is one of the simplest of the irritant poisons. It has a disagreeable bitter taste, and causes, in large doses, dryness of the throat, thirst, vomiting, purging, and pain of the abdo- men. In consequence of its strong emetic propei-ties, it is, in most cases, soon rejected from the stomach ; but in a case reported by Dr. Gibb, in which 67 grains, contained in a lotion, was swallowed by an adult female, there was no vomiting from the poison, and some diflB- culty in relieving the stomach by emetics. It has been administered medicinally in doses of two scruples three times a day for several weeks, without injurious consequences. (Dr. Babington.) The Post-mortem Appearances are those of simple inflammation of the mucous membrane of the stoma(;h and intestines. Treatment. — This consists in the use of a dilute solution of carbonate of potash as an antidote, followed by the free administration of milk, of the white of egg in large quantity, and of liquids containing tannin, such as tea, and decoctions of oak or Peruvian bark. The remainder of the treatment is that common to all the irritant poisons. Chloride of Zinc. — An aqueous solution of this substance is the dis- infectant known as *' Burnett's Fluid." It is a corrosive poison, and produces the symptoms and post-mortem appearances common to the class of coirosive poisons ; and it requires the same treatment. (See Irritant Poisons, p. 317.) Tin.— Chlorides of Tin. There are two chlorides of tin, the proto- chloride and the perchloride. A mixture of these two salts in solution is known by the name oi dyers' spirit. They also exist in the form of yellowish-white acicular crystals. These are the only preparations of tin which require notice. Tests. — The protochloride has the following properties: 1. Sul- phuretted hydrogen or sulphide of ammonium throws down a precipitate of a dark chocolate colour, soluble in an excess of sulphide of ammonium. 2. The bichloride of meicury gives a grey SILVER. 433 Fig 50. precipitate of finely divided mercury. 3. Chloride of gold gives a deep purple precipitate (the purple of Cassius). 4. A fragment of zinc placed in a drop of the solution throws down the metal in an arborescent form, characterized, though not distinguished, by the rectangular arrangements of the branches (fig. 50). One grain of the protochloride in two ounces of distilled water gives characteristic results. These are the tests for the base. The acid is detected by the white precipitate inso- luble in nitric acid, thrown down by nitrate of silver. The perchloride is precipitated yel- low by sulphuretted hydrogen, and sulphide of ammonium, the pre- cipitate being soluble in an excess of the sulphide. In colour, therefore, the precipitated sulphide resembles the sulphide of arsenic and the sul- phide of cadmium. It differs from the foi-mer in being insoluble in ammonia, and irom the latter in being insoluble in hydrochloric acid. Neither corrosive sublimate nor the chloride of gold gives any pre- cipitate with the perchloride. The acid of* the salt may be detected by the nitrate of silver. The salts of tin produce the common symptoms of irritant poison- ing, which muit be met by the free use of albumen or milk, and of diluents. Emetics, or the stomach-pump may be employed if necessary. Silver. — Nitrate of Silver — (Lunar Caustic). This substance is met with in the form of tabular crystals, or fused into small cylinders. It has the following properties : — It is veiy soluble in distilled water, its solution has an acid reaction, and a stiong styptic, metallic taste; is a very powerful corrosive ;. and, when mixed with organic matter, is blackened by light. The base is detected by the following tests : — 1. Sulphuretted hydrogen or sulphide of ammonium yields a black pre- cipitate. 2. Liquor ammoniac throws down the brown oxide, which is dissolved by the precipitant in excess. 3. Hydrochloric acid yields a white clotted precipitate, the chloride of silver, which is insoluble in nitric acid, and when heated on platinum foil fuses into a horny mass. 4. On adding to the solution liquor p,j^ ^^ ammonia;, until the brown oxide is re- dissolved, and then arsenious acid, the yellow arsenite of silver is thrown down. 5. A strip of copper introduced into the solution is speedily coated with silver. 6. If a minute fragment of zinc is placed in a drop of the solution the metallic silver is deposited in an arborescent form (fig. 51). This test is very delicate, a distinct tree (generally in the shape of the shaded figure) being 434 ZINC, TIN, ETC., AND THEIR PREPARATIONS. obtained from a grain of nitrate of silver in eight ounces of water. The acid is detected by adding to the filtered liquid, remaining after the application of the tests, carbonate of potash, when nitrate of potash is formed. No detailed cases of poisoning by nitrate of silver have been placed on record, but from experiments on animals, it appears that it acts as a simple corrosive and local iiTJtant. The treatment consists in changing the soluble nitrate of silver to the insoluble chloride, by the free use of a solution of common salt. Iron. — The sulphate of iron (green vitriol, copperas) and the chloilde, or muriate, of iron possess sufficiently active properties to entitle them to the name of poisons, but they are among the least active of the irritants. The base may be detected by the following tests : — 1. Sulphuretted hydrogen gives no precipitate, but the sul- phide of ammonium throws dov^n a black sulphide. 2. Infusion of galls also gives a black precipitate. 3. Ferrocyanide of potassium throws down a blue precipitate, which deepens by exposure to the air. 4. Sulphocyanide of potassium gives a deep blood-red precipitate. The acid in combination in the sulphate and muriate, respectively, may be detected by the nitrate of baryta and nitrate of silver. The sulphate of iron, arid the chloride in the form of tincture, have both proved fatal, and have in one or two other instances produced severe effects. The symptoms and post-mortem appearances in one case of poisoning by the tincture, recorded by Dr. Christison, were those of a strong irritant. The treatment would consist in the free use of emetics and diluents. Bismuth.^ Trisnitrate, subnitrate, or nitrate of Bismuth. — This substance has proved fatal in a large dose, with the symptoms and post-mortem appearances proper to irritant poisoning. It is found in the form of a white, insoluble powder, which is blackened by sul- phuretted hydrogen, and sulphide of ammonium. It is soluble in nitric acid, but it is again thrown down when the solution is largely diluted with water. The solution resembles that of the salts of lead in being precipitated white by liquor ammonite and liquor potassse, but differs from it inasmuch as it gives no precipitate with dilute sulphuric acid. It gives a deep-brown precipitate with iodide of potassium. Chrome. — The bichromate of potash is much used as a dye. It is found in the form of deep orange-red crystals, which yield a yellow solution. The solution has an acid reaction. With the salts of lead it gives a yellow, and with those of silver a deep-red precipitate. Little is known of the action of this substance on man, but experiments on animals have shown that it possesses the properties of an irritant poison. The treatment would not differ from that proper to the class of irritants. 435 CHAPTER XII. NARCOTIC POISONS. This class of poisons owes its importance less to the number of in dividual poisonous substances which it comprises (for they are few) than to the habitual use made of them by large classes of persons, their constant employment in the treatment of medical and surgical maladies, the many accidents to which they give rise, and the many occasions on which they are employed by the suicide or murderer. For all these reasons combined poisons belonging to this class are used twice as often as the whole class of irritants, and more than fifty times as often as the whole class of narcotico-acrids. The narcotic poisons are characterized by the disorder which they produce in the functions of the brain and spinal cord. In one leading division of the class, comprising opium and its preparations, symptoms of narcotism are the most prominent. In the other, which comprises prussic acid and the substances that contain it, narcotic symptoms are less conspicuous, and are subordinate to the effect produced on the functions of the heart and lungs. In examining this class of poisons we encounter difficulties which do not occur in the case of the class of irritants. The symptoms they produce are moie apt to simulate those of disease, and the post-mortem appearances are often very slight and indistinct. The chemical analysis, moreover, is, on the whole, less sure and satisfactory. The symptoms of narcotic poisoning are giddiness, headache, dimness of sight, noises in the ears, drowsiness and confusion of mind, passing into insensibility more or less complete. Delirium is i-are, and palsy, convnlsions, and tetanic spasms are only of occasional occurrence. The morbid appearances are often slightly marked. They consist in fulness of the veins and sinuses of the brain, with effusion of serum beneath the membranes, at the base, and into the ventricles ; and in some instances extravasation of blood. The treatment of cases of poisoning by the narcotics as a class does not admit of being laid down with precision. The use of the stomach- pump, or of emetics, to discharge the poison ; the cold affusion to rouse the patient ; forced exercise to prevent sleep ; stimulants to re- store the patient from collapse ; warmth and frictions in case of apncea ; and in extreme cases, artificial respiration, and the galvanic shock, are the items of treatment common to the whole class. The narcotic poisons as a class are distinguished from the narcotico- aorids as a class by the absence of irritation of the stomach and bowels. When irritation of any part of the alimentary canal exists, it assumes the form of nausea and vomiting, which occur, not at the commence- 436 KARCOTIC POISONS. mcnt, as in the case of the jrritants and narcotico-aerids, but when the patient begins to recover from tlie effects of the poison. Dianiioea is a raie incident in narcotic poisoning ; but the expulsion of the contents of the bowels often occurs in poisoning by prussic acid as in other violent and sudden deaths. Among the narcotic poisons it is possible to distinguish three classes: — n class, to which opium and its pre)).-! rations, and the narcotic gases belong, characterized by the production of narcotism either without a previous stage of excitement, or with that stage faintly maiked ; a class to which alcohol and the a-thers belong, characterized, though not always, yet often, by a preliminary stage of excitement ; and a class, of which prussic acid and the substances containing it are the only members, which, in fatal doses, kill by syncope or shock, and in smaller doses occasion narcotism and a state resembling apncea. There are several diseases affecting the brain and nervous system, which, in the symptoms they present during life, and the morbid ap- peai-ances they leave after death, resemble moie or less closely the operation of one or other of these three classes of narcotic poisons. Diseases of the heart and large vessels may destroy life suddenly or speedily with symptoms not unlike those of poisoning by a full dose of prussic acid ; and a person may die in an epileptic fit with some symptoms common to it and to poisoning by the same substance. On the other hand, all the poisons of this class which do not prove rapidly fatal, and prussic acid itself in smaller doses, develop symptoms of narcotism which are also present in attacks of apoplexy and of uraemia. Again, many chronic diseases of the brain and spinal cord, and many affections of the nervous system, terminate fatally after decided symptoms of narcotism. It must also be borne in mind that, in infancy and child- hood, convulsions from teething or fjom gastiic or intestinal irritation, as well as narcotism from the state of bi'ain preceding and accom- panying the effusion of serum, ai'e of very common occurrence. It may, therefore, sometimes happen that we are called upon to dis- tinguish certain diseases and their symptoms from the effects of narcotic poisons. This distinction between disease and narcotic poisoning must often present diflficulties in infants and yoiuig children, and occasionally in adults. But we are sometimes greatly assisted by detecting the peculiar odour of the poison, and, in the case of prussic acid and oil of bitter almonds, by finding the vessel from which the poison has been taken on the person or near the body. In other instances, the death is fully ex- plained on the examination of the dead body, by the discovery of organic disease of the heart and large vessels, or of the biain, or of some disease of the kidney capable of giving rise to the poisoned state of the blood known as uramiia. Among the diseases of the heart which may occasion sudden or speedy death it is important to include fatty dege- neration of the substance of the organ which is now admitted among the recognized causes of such deaths. Effusion of serum or of blood DIAGNOSIS. — EPILEPSY. 437 upon the brain or into any part of the cavity of the cranium would not be conclusive evidence of death by disease, as such appearances have been present in one or two cases of narcotic poisoning in healthy subjects. In some cases the interval which has elapsed between the presumed administration of poison. and the first appearance of the symptoms, is such as of itself to rebut the supposition of poisoning. But this means of distinction will be best considered when ti eating of the narcotic poisons individually. Among the fatal diseases to which reference has just been made, there are two of such common occurrence that it may be well to specify some of the best-ascertained facts respecting them for use in cases of difficult diagnosis. Apoplexy, — Apoplexy is sometimes preceded by marked premonitory symptoms of long continuance. It is rare under thirty years of age, while many cases of poisoning by narcotics occur in infants and young persons. Apoplexy sometimes "follows directly upon a full meal ; in other instances on sudden exertion or violent passion. The symptoms of apoplexy manifest themselves suddenly. In many cases of apoplexy there is rather a loss of power to move and to articulate than a loss of the intellectual faculties. In cases of narcotic poisoning, the mind is evidently more strongly affected; the stupor is more complete, but the loss of power much less marked. In the former case, the muscles are paralysed, in the latter, the will. When, however, the apoplectic patient is insensible, he is more difficult to rouse than one who has taken nai'cotic poison. Narcotic poisoris, when they prove fatal, destroy life much more rapidly than most apoplectic attacks. On the other hand, when apoplexy destroys life very rapidly, it does so sooner than any other poison of the narcotic class, except hydrocyanic acid or the nai'cotic gases. The post-mortem appearances in cases of apoplexy generally differ from those due to poison. Eflusion of blood on the surface, in the ventricles, in the substance, or at flie base, of the brain, is rare in poisoning, so that its presence affords a strong presumption in favour of sanguineous apoplexy. A copious effusion of serum in the same situation affords a less forcible presiunption in fiwour of serous apoplexy ; while a mere turgescence of the veins and sinuses of the brain furnishes in itself an equal presumption in favour of poisoning or of simple apoplexy. Epilepsy. — Epilepsy is one of the occasional symptoms of irritant poisoning, and of poisoning by the narcotico-acrids. It also resembles acute poisoning by prussic acid. When it is merely one of a group of symptoms due to poisoning, the concomitants will serve to distinguish it at once from a case of simple epilepsy. The points of distinction most insisted upon are the following: The epileptic fit almost always begins abruptly, and in most cases without any previous warning ; and the premonitory symptom , if present, is rarely such as to be con- 438 NARCOTIC POISONS. founded with the effects of a narcotic poison. The symptoms of narcotic poisoning, also, gradually increa.se in severity. In epilepsy the patient cannot be roused by external stimuli. The reverse obtains in most cases of narcotic poisoning. In fatal cases of epilepsy, death does not take place so rapidly as in poisoning by prussic acid, and gene- rally after a longer interval than in poisoning with opium. Epilepsy very rarely, if ever, proves fatal in the first paroxysm. Prussic acid, the poison which produces the symptoms most resem- bling epilepsy, would be at once detected by its odour. In fatal cases, the morbid appearances render little assistance to the diagnosis. There are no morbid appearances proper to epilepsy, but the brain is otten found extensively diseased. If that disease is of a very marked cha- racter, it renders the supposition of poisoning improbable ; but if it consist simply in congestion, or in a moderate effusion of serum, it is consistent with the supposition of poisoning, apoplexy, or epilepsy. If death take place with symptoms similar to those of narcotic poisoning within the time at which such poisons may prove fatal, lecourse must be had to the post-mortem appearances. These will often be of so marked a character as to explain the death without having recourse to the supposition of poisoning. But if the post-mortem appearances should happen to be such as are found in cases of poison- ing, recourse must be had to an analysis of the contents of the stomach, which may issue in rendering the previous exhibition of poison impro- bable, or in proving that this was the cause of death. The most important of the narcotic poisons are opium and hydro- cyanic acid. Alcohol, ether, and chloroform follow next in order, and a feeble narcotic poison, lactuca, completes the list of simple narcotics. The principal narcotic gases are, carbonic acid, carbonic oxide, and sulphuretted and carburetted hydrogen. Some poisons usually classed with the narcotics will be considered as narcotico-acrids. The relative importance of the two principal poisons of the narcotic class — opium and prussic acid — is shown by the fact that, on the average of the five years 1852 to 1856, opium and its preparations were administered in 141, and prussic acid and its preparations in 34, cases of poisoning, in which the nature of the poison was distinctly specified. 439 CHAPTER XIII. OPIUM AND ITS PREPAKATIONS. The importance of opium and its preparations as poisons will be understood from the statement, that of the 543 cases of poisoning brought under the notice of the Coroner's court in England and Wales, during 1837-38, no less than 200 were cases of poisoning by opium or its preparations, either alone or in union with other poisons. This number exceeds the total of cases (184) of poisoning by arsenic. Of these 200 cases, 42 were by solid opium, 133 by laudanum, 21 by other preparations containing opium, 2 by acetate of morphia, and 2 were cases of mixed poisoning (laudanum and prussic acid, and lau- danum and aquafortis). Of the 200 cases, 64 occurred in children, and the remainder in adults, and of these 64, 41, or a fifth of all the cases, were from over doses of cordials or medicines, administered to infants and young children by their mothers or nurses. Since the years 1837-38 great changes have taken place in the com- parative frequency with which the different poisons are employed. In consequence partly of the legal enactment restricting the sale of arsenic, and partly of the increased knowledge of the properties of other poisons, opium and its preparations, which in 1837-38 formed four in eleven of all the recorded poisons, constitute on the average of the five years 1852-56 more than one-half of the deaths by ascertained poisons. The total annual average of deaths by ascertained poisons being 268, no less than 141 were attributed to opium and its several preparations, while prussic acid and its compounds accounted for 34 deaths, and arsenic and its preparations for only 27 deaths. Opium itself caused, on the average of these five years, 34 deaths, laudanum 89, Godfrey's cordial 16, and morphia 2. The cases of poisoning by opium and its preparations, in the five years, 1852-56, in which the ages of the victims were ascertained, amounted to 377 ; of which number 170, or nearly half, occurred in infants under one year of age, and 203 in children under five years old. In adults the great majority of cases were suicidal. Only one murder and one manslaughter (by laudanum) are reported in the whole five years. Opium and its preparations, especially laudanum, are sometimes given to facilitate the commission of other ciimes, such as theft and rape. In such cases the taste and colour are generally concealed in brandy or coffee, and the poison is given after the sense of taste has been deadened by intoxicating liquoi's. The capsules of the Papaver somniferum (white, or garden poppy) 440 Ol'lUM AND ITS PltErAUATlONS. lumish several piopirations to the London Phannacopcoifi — a decoction for external use, a syrup given chiefly to infants, and an aqueous extract (otractum i)apavei'is), in addition to the inspissated juice known FJg. 52 ^s opium. A decoction of the capsules, or poppy heads, not authorized by the Pharniacopoeia, is sometimes given to infants with fatal effect. As the seeds from the capsule have been found in the stomach, and as the seeds taken by themselves have proved fatal in some instances abroad, the annexed wood-cut is given to show their size and microscopic character. They weigh about 230 ^to the grain. Some of the seeds are white, others grey. Opium, the inspissated juice of the unripe capsules, has the follow- ing familiar properties: It is of a reddish-brown colour, of a strong and peculiar odour, and a bitter and lather acrid taste. Different specimens of the drug vary in physical properties, and in activity, with the place of growth, the maturity of the capsule, the greater or less care bestowed on the manufacture, and the presence or absence of aduiteiation. The quantity of morphia may vary from 2 to 28 per cent, and the quantity of meconic acid bears no fixed proportion to the moii)hia which it holds dissolved. The average quantity of morphia in good Turkey opium is about 10 per cent., and the nipconic acid is usually stated at 6 per cent. The drug consists of a number of distinct principles combined with a peculiar acid, and mixed with resin, and extractive matter. These principles are dissolved by water at ordinary temperatures, by alcohol, and by mineral and vegetable acids. The preparations of opium in the London Pharmacopoeia are: — The tincture, or Laudanum, which contains one grain in thirteen drops ; the compound tincture of camphor, or Paregoric, which contains one grain in the half ounce ; the extract of opium, a preparation of some- what variable strength; the confection, which contains one grain in thirty-six; the compound ipecacuanha, or Dover's powder, which con- tains one grain in ten ; the compound opium and chalk powder, which contains one grain in forty ; and the compound kino powder, which contains one grain in twenty ; the compound soap pill and compound styrax pill, which contain one grain in five. The vinum opii, fre- quently dropped into the eye, the enema opii, consisting of thirty diops of the tincture in ^iv of starch, the emplastrum opii, the unguentum opii, and the unguentum Gallae compositum, complete the long list of phai-macopoeial preparations containing opium. The black drop said to contain two, three, or four times as much opium as the tincture, and Battley's liquor opii sedativus, of which twenty drops are said to be equal to thirty of laudanum, are also in common use. The first is made with verjuice and aromatics, the second is believed to be an aqueous solution. Godfiey's cordial, Dalby's car- minative, children's quietness, and several mixtures improperly given to children to procure sleep, contain laudanum as their chief ingredient TESTS FOR MORPHIA. 441 in combination with syrups, stomachics, and magnesia. The quantity of laudanum in these preparations is very variable. Opium contains several active principles. Morphia, narcotine, nar- ceine, meconine, thebain or paramorphia, codeia, papaverine, and me- conic acid, have been separated ; but the most important, indeed the only ones of any medico-legal importance, are morphia and meconic acid, wliich exist in combination in opium as a meconate of morphia. Opium may be recognized by the reactions of these two substances, as well as by its odour and other physical properties. The morphia and meconic acid are extracted and separated by the following process: The opium is infused in successive portions of cold water. This aqueous solution, which holds the active principles of the drug dis- solved, is boiled with magnesia, in combination with which the active principles are thrown down. The precipitate thus formed, after being washed and dried, is boiled with proof spirit, which dissolves the nar- cotine and the resin, leaving the morphia and a meconate of magnesia behind. To separate the morphia from the meconate of magnesia the preci- pitate is boiled in strong alcohol, which dissolves the morphia mixed with some resin. From this impure spirituous solution, the morphia may be obtained pui-e by crystallization or by digesting it with animal charcoal. To obtain the meconic acid, the impure meconate of magnesia is boiled in dilute sulphuric acid, and the mixture partially evaporated. The sediment which falls on cooling is dissolved in water, and acetate of lead is added to the solution. A meconate of lead is thus formed. This is washed and suspended in water, and a stream of sulphuretted hydrogen gas is transmitted through it. Sulphuret of lead is thrown down, and meconic acid left in solution ; and on evaporation, impure scaly crystals of meconic acid are obtained. TESTS FOR MORPHIA AND MECONIC ACID. Morphia. — Properties : — 1. It is sold as a white powder, or as crystals, which when quite pure are colourless; but they are generally more or less discoloured by resin. Their form Fig. 53. is the six-sided prism (tig. 53). Crystals, or ^^ , the fragments of crystals of this shape may he / '■; /-A recognized in good specimens of the alkaloid, i j ' ' 2. They have a bitter taste, but no odour. I /' "" 3. When heated, they first melt into a yellow ^^ oily liquid, then burn like a resin, leaving a carbonaceous deposit of a semi-crystalline appearance, and giving out ammonia. 4. They are very sparingly soluble in cold water, sparingly soluble in hot water, more soluble inaather, and still more so in alcohol. They are soluble in the caustic alkalis, and very soluble in the mineral and vegetable acids, in combination with which they are used in 442 OPIUM AND ITS PllEPARATIOKS. medicine. 5. In solution they have a slight alkaline reaction. 6. In common with other alkaloids, morphia is precipitated from its solutions by tann'c acid, biniodide of potassium, and corrosive sub- limate. Tests.~l. Nitric Acid, 2. The Permuriate of Iron, 3. Iodic Acid and Starch, 4. SulpJturic Acid, and Bichromate of Potash. When these tests are applied to moi-phia, or to its salts, in substance, a white surface of porcelain should be used, and the reagents applied in quantities proportioned to the substance tested. 1. Nitric Acid. — When morphia is treated with nitric acid, it becomes instantly orange-red, and is dissolved with efiervescence, nitrous acid fumes being given off. On standing, or on the addition of a larger quantity of acid, the colour of the solution changes to a bright yellow; and on heating it, it becomes of a straw colour. Nitric acid causes the same change of colour in moderately strong solutions of morphia. 2. Permuriate of Iron. — This test added to the ciystals, or to a solution of morphia, or to morphia suspended in water, strikes a rich indigo-blue colour, turning to green when added in excess. The test should be neutral. It should not be applied to a hot or acid solution. If the test, or the solution, has an acid reaction, it should be neutralized by caustic potash. 3. Iodic Acid and Starch. — Morphia, when added to iodic acid, combines with its oxygen, and sets the iodine free, which may be detected by its brown colour, and the deep blue which it strikes with starch. The iodic acid must not contain free iodine ; nor must it be applied to an acid or hot solution. This is a very characteristic and delicate test, but liable to be interfered with by slight causes, and requiring time for the complete development of its effect. 4. Sulphuric Acid and Bichromate of Potash. — Strong sulphuric acid added to morphia in substance either produces no effect, or gives it a straw-tiut ; but on adding a solution of bichromate of potash, the mixture assumes first a rich brown tint and then rapidly changes to a green colour, due to the formation of the oxide of chrome. When these four tests for morphia act characteristically on a white powder or colourless crystal, or on a colourless solution of a white powder or crystalline substance, there can be no doubt of the existence of morphia. Meconic Acid. — This acid assumes the form of scaly crystals, which when impure are dusky red, when pure of a pale yellow colour, when quite pure almost colourless. They are soluble in cold water, and more soluble in hot water, the resulting solution having a strong acid reaction. When heated in a glass tube the crystals are partly decom- posed and paHly sublimed, and the sublimate condenses on the sides of the tube in the form of filamentous ladiated crystals. Meconic acid is precipitated from its solutions by acetate of lead, as a meconate of lead, TESTS FOE MECONIC ACID. 443 which is insoluble in acetic acid. The only test of any value for meconic acid, whether in crystals or in solution, is one which has been just mentioned as a test for morphia, viz. : Permuriate of Iron. — This reagent strikes with meconic acid an in- tense cherry-red colour, which is discharged by a solution of the protochloride of tin, but not by the dilute mineral acids, or by the solutions of bichloride of mercury and chloride of gold. The test gives a similar reaction with the sulpho-cyanide of potas- sium, with the saliva which contains that salt, with common mustard in solution, and with the alkaline acetates ; but this fact does not con- stitute an objection to the test for meconic acid obtained from a solution of opium, or from an organic fluid by the process now to be described. If the tests for morphia and meconic acid act characteristically, the evidence of the existence of opium in the liquid from which they were obtained is conclusive. Opium in Organic Mixtures. — In consequence of the important corroboration which the detection of meconic acid affords to that of morphia the process for organic mixtures should be one which separates both the alkaloid and the acid. A solution of opium itself may be regarded as a suspension of its active principles in an organic mixture, for opium, in addition to those principles, contains 5 large amount of resin and extractive matters. The process for the detection of the morphia and meconic acid in the contents of the stomach is as follows : The solid mattei's, if any, must be cut into small fragments, and well mixed with the more liquid contents, distilled water being added if necessary. The mixture must then be slightly acidulated with acetic acid, and after being allowed to stand for several hours must be filtered, evaporated to the consistence of a syrup, and treated with a solution of acetate of lead, so long as any precipitate falls. The liquid must then be boiled and filtered. An impure meconate of lead remains on the filter, while the fluid part contains the morphia. This impure meconate of lead must now be suspended in distilled water, and sul- phuretted hydrogen must be transmitted through it. A sulphuret of lead is formed, and meconic acid remains in solution. This solution may be concentrated by evaporation, and the acid may be obtained in a state of greater purity by repeating the process. The fluid part which contains the morphia is next to be treated with sulphuretted hydrogen gas, by which any lead it may contain is thrown down as a sulphuret. The liquid must again be filtered, and on being reduced by evaporation to the consistence of a syrup, and treated with alcohol, the acetate of morphia is dissolved, and may be obtained in the form of crystal. The meconic acid and the morphia may be identified by their proper tests. Though other processes have been recommended, this process, which has the advantage of separating both the meconic acid and the morphia, is in skilful hands a satisfactory one. Christison states 444 OPIUM AND ITS PREPARATIONS. (p. 641), that by a process similar to the one just described, he has succeeded in obtaining distinct evidence of morphia and meconic acid by all the tests, in an infusion of ten grains of opium in four ounces of water. But on proceeding to apply the process to organic mixtures he found that when the soluble part of ten grains of opium was mixed with four ounces of porter or milk, he could detect no property of morphia, except its bitterness, and but faint indications of meconic acid by the permuriate of iron. The fact now stated would lead us to expect few or no traces of opium in the stomach in the majority of cases of poisoning by it and its preparations. Very laige quantities of the drug in its fluid pie- parations may be taken, and yet be detected neither by the odour, nor by the taste, nor by the several tests, even where death takes place most rapidly ; and it may be stated as a general rule that, in poisoning with opium, the medical jurist, by the best methods of analysis yet known, will often fail in procuring satisfactory evidence, and sometimes fail to obtain any evidence at all, of the existence of the poison in the contents of the stomach. Even the odour may be absent in the liquid removed within half an hour after an ounce and a half of laudanum has been taken on an empty stomach, and when present is so mixed up with other odours, that it cannot be detected with any certainty. (Bright's ' Reports of Medical Cases,' ii. 203). Fiom what has now been stated it will be inferred that we have no reason to expect the discovery of opium in the secretions or solids of the body by any process of analysis, though there is no reason to doubt that the poison is absorbed, circulated in the blood, and deposited in the tissues. For information on this point, and for a description of other modes of dealing with organic liquids see * Taylor on Poisons,' 2nd edit., p. 631. SYMPTOMS, POST-MORTEM APPEARANCES, AND TREATMENT. Symptoms. — There is so much difference between the symptoms present in different cases of poisoning by opium, and at different stages of the action of the drug, that it is quite impossible to give the his- tory of an average case of poisoning within the ordinary compass of a description. The symptoms due to a poisonous dose of opium, or its prepara- tions, are giddiness, drowsiness,' and listlessness, followed by stupor, passing by degrees into a state of complete insensibility. The patient lies as if in profound sleep, breathing slowly and almost impercep- tibly, with the eyes shut, the pupils contracted, the pulse either very iVeq'uent, or full and slow, the skin warm and moist, and the face flushed. At first the patient can be easily roused by loud noises, sudden movements, or slight blows ; but, in a more advanced stage, lie is kept awake with great difficulty, by violent shaking, loud speak- ing, tickling the nostrils, injecting water into the ear, or flecking the FIRST APPEARANCE OF THE SYMPTOMS. 445 hands and feet with a towel ; and at length falls into a state of com- plete coma, with stertor, slow and noisy respiration, a slow and full pulse, a pale countenance, and livid hands and lips. Nausea and vomiting are sometimes present from the first, but in other cases they are among the early signs of recovery. When the patient is kept roused, by being briskly moved about, he is subject to constant retch- ing, even though no emetic has been used. The bowels are generally confined. In fatal cases death takes place sometimes as in apoplexy, sometimes in a state of collapse, sometimes from apnoea, sometimes in convulsions, sometimes in a palsied state. In patients who recover, a long deep sleep with a remarkably slow breathing (I have counted it in a female as low as 6 in the minute, while the pulse was upwards of 80), is followed by a stage of painful nervous excitement, with head- ache, and distressing nausea. The recovery is ultimately complete. Occasional Symptoms. — Spontaneous Vomiting, Diarrhoea, Diuresis : Delirium, convulsions (most common in children), sometimes alter- nating with stupor, locked-jaw and tetanic spasms, paralysis, anae- sthesia, dilated pupils, or one pupil dilated the other contracted (Taylor), and the reflex function active, and easily excited, though the patient is otherwise quite insensible. The pulse sometimes nearly natural in frequency and force ; in other cases full and accelerated, but this happens chiefly in the first stage. In the stage of insensi- bility, while the patient can still be roused, the pulse is generally full and slow, but towards the fatal termination it becomes small, frequent, and iriegular. The respiiation is much more uniformly affected than the pulse. Itching and dryness of the skin are also among the occasional symptoms. Anomalous Cases. — An absence of the usual narcotic symptoms, with sudden death. A long postponement of the symptoms. Recovery for a time, with fatal relapse. Post-mortem Appearances. — These are neither constant nor well marked. The most usual are turgescence of the vessels of the brain, with or without serous effusion under the arachnoid, into the ventricles, at the base, and around the spinal cord, very rarely accom- panied by extravasation of blood. The stomach and intestines are generally healthy, Lividity of the skin, congestion of the lungs, a fluid state of the blood, and early putrefaction of the body are among the less constant appearances. First Appearance of the Symptoms. — The poison, when taken in large quantity, and in a fluid state, may begin to act within a few minutes, and coma may be fully formed within half an hour. Even when taken in the solid form, complete stupor has been present in as little as fifteen minutes. Sometimes, however, the action of the poison, even though a large dose has been taken, is postponed for half an hour, an hour, or an hour and a half; and cases are even on record in which large quantities of the poison have not produced any serious effect till the lapse of 3, 5, 9, 10, and even 18 hours. One of the 446 OPIUM AND ITS PREPAEATIONS. most recent of this curious cla«s of cases was published in the ' Lancet,' July 15, 1857, by Dr. Gibbs. Twelve drachms of laudanum were spontaneously lejected from the stomach at the end of 9 houre, without having given rise to any marked symptoms. The patient was a little exhausted, and the pupils were contracted. The action of the poison is more prompt when taken on an empty than on a full stomach ; when in a liquid state than when swallowed in the solid form ; when the patient remains still than when he takes exer- cise immediately after swallowing the poison ; and it is probable that the action is postponed and diminished by spirituous liquors. The shortest period within which opium or its preparations have proved fatal to adult persons is three quarters of an hour. Cases of death in two hours are reported by Beck and Taylor ; few cases are prolonged beyond twenty-four hours, and the average may be stated at from seven to twelve hours. When a patient survives twelve hoars there is good hope of his recovery. The smallest quantity of opiunj which has proved fatal in the adult is four and a half grains.* A quantity of the extract equivalent to four gi-ains of solid opium has also destroyed life. Enormous quanti- ties liave been taken with impunity. In one instance recovery took place after no less than eight ounces of solid opium. In very young children extremely small doses produce very marked effects, and have proved fatal. Cases are on record in which an eighth of a grain of opium, or its equivalent, has killed an infant two days old, a sixth of a grain an infant of four, and another of five days, a fifth of a grain an infant of three days old, a third of a grain an infant of nine months, and another a few weeks old, a fourth of a grain a child of fourteen months, less than half a grain a child of four years and a half. Two drops of laudanum killed an infant. Severe symptoms have been produced by a single grain of Dover's powder, containing a tenth of a grain of opium. A child of four months, and several infants, have suffered severely from quanities of laudanum equivalent to the sixth of a grain of opium. t Death has happened, in the instances referred to, in intervals of time varying from 7 to 18 hours. As in the adult, so in infants and young children, recovery has taken place after considerable doses of opium. In a case under my own observation a child of six months recovered from ten grains of Dover's powder. There are some persons on whom comparatively small dosets of opium and its preparations, in consequence of peculiarity of constitu- tion, produce unusually severe effects. On the other hand, the power of habit in lessening the effect of the poison must not be overlooked. Opium, like tobacco, may be taken in constantly increasing doses • This was mixed with nine grains of camphor. Case reported to Dr. Chrlsti- son by Mr. W. Brown. ' On Poisons,' p. 657 t Vov details of these cases, with the particular preparations given, see the works on Toxicology of Christison and Taylor. TREATMENT. 447 with impunity. Thirty grains of sohd opium, and even one hundred grains, are often taken in tlie day by opium eaters, and De Quincey, the English opium eater, brouglit himself to take nine ounces of laudanum, equivalent to 333 grains of solid opium in the day. There is scarcely a druggist in London who has not seen laudanum swallowed by the wine-glassfull ; and I am informed that the Lascar beggars purchase half an ounce of opium a day, from which they procure a watery extract which they smoke with tobacco. Opium, when thus taken habitually in large quantities, and for long periods, causes emaciation and loss of vigour, loss of appetite and con- stipation, loss of mental vigour, severe neuralgic pains, premature old age, and early death. Hobhouse describes the opium eaters of Con- stantinople as ' pale, emaciated, and rickety, sunk into a profound stupor, or agitaied by the grimaces of delirium.' Mr. Madden and Dr. Oppenheim confirm this account. The former adds, that a regular opium eater seldom lives beyond thirty years, if he commence the practice early ; and the latter tells us that those who begin the practice early seldom attain the age of 40. In the face of these explicit statements, and of the extreme impro- bability that a habit so unnatural should not affect the duration of life, it has been denied that the practice of opium-eating tends to shorten life. There is no doubt that many persons who indulge in it (but in a less degree than in the cases referred to by Hobhouse, Madden, and Oppenheim), live to a good age; but it is probably with opium as with spirits and tobacco, those who indulge in them and live long would attain a much greater age if their habits of life were other than tjiey are. At any rate, the facts hitherto collected are not sufficient to decide this question.* Opium applied to the skin, and especially to an abraded surface, or used in the form of injection, or introduced into the nostril or ear, may produce dangerous or fatal results. M. Tournon, of Bourdeaux, relates a case in which death was attributed to four grains of opium introduced into the external meatus of the ear. Treatment. — The treatment must begin with the use of the stomach- pump, and warm water should be freely injected and withdrawn till it is discharged without odour and colour. If the stomach-pump cannot be immediately applied, an emetic of sulphate of zinc should be given ; or, if this is not at hand, a table-spoonful of mustard, mixed with water. At the same time, vomiting should be encouraged by the free use of warm water, and by tickling the throat with a feather. If the pitient is comatose, cold water should be freely dashed over the face, head, and neck, till he is somewhat roused from the stupor, and he must then be kept awake by causing him to walk rapidly between two assistants, shaking him arid shouting to him. In small apartments, where it is inconvenient to move the patient about, the object of keeping the patient roused may be accomplished by flecking * For cases, see Christison on the case of the Earl of Mar, p. 661. 448 MOIIPHIA AND ITS SALTS. the hands and feet with a towel. When the patient is beginning to recover, strong coiVee should be freely administeied. If emetics ad- ministered by the mouth do not act, they may be injected into the bowels, and, in hopeless cases, a solution of tartar-emetic might be introduced into a vein. Galvanism and artificial respiration have been used in extieme cases. When the symptoms present are those of collapse, ammonia may be freely given internally and applied to the nostrils ; when those of apncea, warmth and friction to the surface are indicateil ; when those of cerebral congestion, the moderate ab- straction of blood by bleeding or leeches. In the stage of excitement which follows lecovery, as well as in the early stage of the poisoning, cold affusion has been practised with excellent effect. MORPHIA AND ITS SALTS. Of this alkaloid, which is found in opium in proportions varying from 2 to more than 10 per cent., there are three salts in use in medi- cine— the acetate, hydrochlorate, and sulphate, of which the first two supply officinal preparations, namely, the liquor morphia' acetatis and the liquor morphias hydrochloratis, which contain one grain of the salt in a drachm. The hydiochlorate of morphia is the preparation in most common use, and its ordinary dose for the adult is an eighth of a grain. The acetate of morphia is sold as a snow-white powder, or as imperfectly formed crystals, and the hydrochlorate either as a white powder, or in the form of silky acicular crystals. Both salt have the chemical reactions of moi-phia itself. Symptoms. — Those of opium and its preparations. The symptoms set in somewhat earlier, and contraction of the pupils, with great dim- ness of vision or actual blindness, is a very constant symptom. In- tense itching of the skin is also very common, and dysuria, tetanic spasmi, and strong convulsions are among the occasional symptoms. Anomalous Cases. — In one case reported by Dr. Shearman (' Med. Times and Gazette,' Maich 7, 1857), a grain and a half of the acetate of morphia in divided doses caused twitching of the limbs and face, with difficulty in swallowing, spasms of the muscles of the arms and legs, and of the muscles of the abdomen, partial o{>isthotonos, and great activity of the reflex function. Morphia was found in the urine. The patient recovered. A similar case of poisoning by twenty-two giains of the muriate of morphia, in which locked jaw, tension of the abdo- men, and occasional convulsions, were present, is related byOrfila, and cited by Christison (p. 725). In one case, also, delirium seems to have followed its application to a blistered surface. It is worthy of observation that Augustus Ballet, the ]>resumed victim of Castaing, had, in addition to vomiting and purging, con- vulsions, locked jaw, rigid spasms of the neck and abdomen, inability to swallow, loss of sensibility in the legs, contracted pupils and stertorous breathing : and that Castaing, who prescribed for Ballet, and gave him FATAL DOSE. TREATMENT, 449 food and medicine, was pioved to have recently purchased twelve grains of tartar emetic, and twenty-six grains of acetate of morphia. John Parsons Cook, the victim of William Palmer, took two pills containing half a grain of acetate of morphia on each of the two nights preceding his first attack ; and on the night of the attack itself two pills were given by Palmer, and again two pills on the occurrence of the tetanic symptoms. On the succeeding night, which was the night of his death, Cook also took two pills given him by Palmer, who had previously obtained the acetate of morphia pills from the medical attendant; and during the fatal attack two other pills, said to contain ammonia, were given. If all these pills contained acetate of morphia in the dose first prescribed, an aggregate of three grains would have been given within three days, of which quantity tvw grains were administered in little more than twenty-four hours. As the lady attended by Dr. Shearman was severely attacked with symptoms of tetanus from taking three doses of half a grain of acetate of morphia within seven hours, it is quite possible that the same drug in the same dose, and the aggregate of three grains in the space of seventy-two hours, may have proved fatal to a patient previously reduced by tartar emetic. Jt is not intended by these observations to raise any doubt of the guilt of Palmer, but merely to suggest the possibility of the death of Cook having been occasioned by acetate of morphia and not by strychnia. Fatal Dose. — In the case of this, as of most other active poisons, very large doses have been taken with impunity, and very small ones, in certain states of the system, have been followed by dangerous symp- toms. One case has been reported in which half a grain of the acetate of morphia given as a medicine to a female in ill health was supposed to have proved fatal (* Lancet,' Nov. 1838), and it is probable that less than a grain of morphia given in one dose would prove fatal to an adult. Treatment. — That proper to poisoning by opium and its prepara- tions. Finely-divided animal charcoal suspended in water might be administefed with advantage after the use of the stomach-pump. 2g 450 CHAPTER XIV. HYDROCYANIC ACID. Hydrocyanic, or prussic acid, with essential oil of bitter almonds, of which it is the active principle, and cyanide of potassium, one of its salts, form a gi-oup of poisons ranking next to opium and its prepara- tions in the frequency with which they are taken as poisons. In the two years 1837-8, twenty-seven cases of poisoning by prussic acid were brought under the notice of the coroner's court, of which eight (all cases of suicide) occurred in medical men and druggists. Four cases of poisoning by essential oil of almonds also occurred in those years, and one of poisoning by prussic acid mixed with arsenic. Prussic acid, with its preparations and compounds, caused, on the average of those years, sixteen deaths. But on the average of the five years 1852-56, they were credited with 34 out of the 268 deaths from ascer- tained poisons. The use of this poison is, therefore, on the increase. In the five years, 93 deaths were attributed to prussic acid, of which 83 in males and 10 in females ; 75 to the essential oil of almonds, of which 45 in males and 30 in females; and 2 to cyanide of potassium, of which one in a male the other in a female. The great majority were adults. One murder only was committed by any of these substances ; and that one was by the essential oil of almonds. The remainder of the deaths were suicidal or accidental ; and 75 by prussic acid, 51 by essential oil of almonds, and 1 by cyanide of potassium were ascertained suicidal acts. This poison is remai'kable for its quick and fatal effect, and this, coupled with the frequent use of the essential oil of almonds in cookery, and of the cyanide of potassium in the arts, renders it a favourite instrument of suicide. It has been only occjuiionally used as an instru- ment of murder. For medicinal purposes, the acid is formed by a complex chemical process, or by the decomposition of salts which con- tain it ; but it also exists in the leaves, Howers, and fruit-kernels of many plants belonging to the natural order Kosaceaj. The bitter almond, the cherry -laurel, the peach, the cluster cheny, and the mountain ash ; the kernels of peaches, plums, and cherries, and the pips of apples, contain it. The prussic acid obtained from these sources is mixed with an essential oil, and distils along with it. The cherry- laurel water was administered as a poison in the well-known case of Sir Theodosius Boughton; and a bitter almond water improperly kept in the shops of very variable strength, and incautiously prescribed, has also proved fatal. DILUTE HYDROCYANIC ACID. 451 The acid is met with under two forms ; as a pure anhydrous acid, and diluted with water. The pure anhydrous acid is limpid and colourless, has an acrid pun- gent taste, and a peculiar odour. It boils at 80°, freezes at 5°, and at ordinary temperatures readily freezes by its own evaporation. If left exposed to the light, it soon decomposes and turns brown. It is highly inflammable. The pure acid is not likely to come under notice in medico-legal cases : it is the dilute acid, as kept in the shops, that is commonly used as a poison. Dilute Hydrocyanic Acid. Properties. — The dilute acid has the same appearance, odour, and taste as the stx'ong acid, but provided it be kept from the light, is not so apt to decompose. Like the strong acid it is volatile, though in a less degree, and loses its activity by exposure. But the acid obtained by decomposing a solution of ferrocyanide of potassium by sulphuric acid is much more stable, and has been kept for years, even exposed to diffused light, without undergoing decomposition. The quantity of the sti'ong acid contained in the dilute acid employed in medicine differs with the mode of preparation, and the time that it has been kept. As found in the shops, the strength has been found to vary from 1'3 to 6*5 per cent. (Taylor.) This variation of strength in the same medicinal preparation is well illustrated by the case of a French physician re- ferred to by Christison, who swallowed a whole ounce of one sample of Scheele's acid, and a drachm of a stronger sample without injury ; but on trving some recently prepared by Vauquelin, he had a narrow escape of his life. The prussic acid of the London Pharmacopoeia should contain about 2 per cent., that of Vauquelin, 3-3 per cent., and that of Scheele about 5 per cent. The strength of the dilute acid employed in other coun- tries varies from 1 to 25, or even 50, per cent. Among the properties of prussic acid just described, there is one which is so characteristic and so delicate as to be justly regarded in the light of a test, namely — The odour. — This is peculiar, and generally perceptible even where the acid is present in very small quantity. As a test, it has the advantage of not being dependent on any chemical knowledge or skill on the part of the observer, and when perceived by more than one person, and especially when recognized by several persons at the same time, it is conclusive of the presence of the acid. It has, indeed, been alleged that the odour of prussic acid is not decisive ; because nitro- benzole, one of the products of coal-tar, and some other artificial products used as scents or flavours, have a like odour, and because the brain itself has an odour similar in kind though faint in degree. Of nitro-benzole it will suffice to observe that it is itself an active poison ; of the objection founded on the faint similar odour of the brain, that it 452 HYDROCYANIC ACID. has a very limited application in post-mortem inspections, and of both that they are very unlikely ever to constitute real objections. The odour of the acid, considered as a highly characteristic property and test, finds its application both during life and after death — during life, as indicating at once what poison has been taken, by the odour dif- fused through the air, or perceptible in the breath; in the dead body, as equally indicating the presence of the poison in the contents of the stomach or in the tissues. In patients under treatment, the odour of the acid may be disguised by that of other remedies, as in a case which fell under my observation, in which assafffitida had been administered in an injection. The odour, as perceived in the dead body, is generally recognizable soon after death, but it often disappears in less than twenty-four hours. In the case of Sarah Hart, the victim of Tawell, the odour was recog- nized by two only out of five witnesses, eighteen hours after death. In a case i-eported by Mr. Newham, of Bury St. Edmunds, it was perceived eleven hours after death in the stomach, heart, and brain ; and in an interesting case of double suicide (that of C. W. Duckett and Elizabeth Williams, reported by Dr. Letheby), it was perceived about the mouth twelve hours, and according to Mr. G. Davies, seventeen or eighteen hours after death. The odour of prussic acid is therefore to be regarded as a highly characteristic property, and even a valuable test of the presence of the poison. Tests. — There are four recognized tests for prussic acid, which may be briefly designated as the copper, silver, iron, and sulphur tests. These tests are equally applicable to the acid in solution and in vapour. 1. Copper Test. — A solution of sulphate of copper added to a liquid containing hydrocyanic acid gives characteristic results. The liquid is first rendered slightly alkaline by liquor potassaj; and on adding the solution of sulphate of copper, a greenish-white precipitate is thrown down, which, on the addition of a little hydrochloric acid, becomes nearly white, the blue oxide of copper which is mixed with the white cyanide being re-dissolved. Though this test was recommended by Lassaigne as a very delicate one, it is less characteristic than the three remaining tests. 2. Silver Test. — A solution of nitrate of silver gives with liquids containing hydrocyanic acid a white clotted precipitate, distinguished from the other white precipitates thrown down by nitrate of silver, by its insolubility in nitric acid at common temperatures, and its solubility at a boiling heat. If the precipitated cyanide of silver, after being well washed and dried, is introduced into a small tube closed at one end, and drawn out at the other into a fine point, and the precipitate is heated by the flame of a spirit-lamp, cyanogen gas is given off, which, on being lighted, burns with, a highly characteristic crimson flame, sur- rounded by a blue halo. 3. Iron Test. — Add to the suspected liquid a slight excess of liquor IRON AND SULPHUR TESTS. 453 potassse, then a few drops of a mixture of the proto-sulphate and per- sulphate of iron iu solution. A brownish-green precipitate is thrown down, which, on the addition of a little dilute hydrochloric acid, becomes Prussian blue. 4. Sulphur Test. (Liebig's Test.) — To the liquid containing the acid add a few drops of the sulphide of ammonium ; then heat the liquid gently till it becomes a pure white or colourless ; then evaporate slowly. A white amorphous sulpho-cyanide of ammonia remains, which assumes an intense cherry-red colour when touched with a solution of the perchloride of iron. This colour is^^discharged by a solution of corrosive sublimate. When these tests are applied to detect the acid by its vapour, the following method of procedure is to be observed : — Place the fluid or substance yielding the vapour iu a watch-glass; moisten a large flat disc of glass with the test; invert it over the watch- glass, with the moistened surface downwards, and allow it to remain for ten minutes or more, or till a distinct reaction is perceptible through the glass. Or, place the liquid or substance in a small wine-glass with a conical stem, moisten with the test two flat glass discs — a smaller and larger one — and insert them over the contents of the glass, so that the vapour which passes the first disc may act upon the second. In the case of the copper-test use a solution of sulphate of copper, of the strength of 1 gr. to the ounce. Moisten the disc of glass with a drop of this solution rendered slightly alkaline by dilute liquor potassa^ ; and after exposure add a drop of dilute hydiochloric acid. Compare the dried stain with the stain from a drop of the test-solution of sul- phate of copper. In the case of the silver-test, moisten the glass disc with a solution of nitrate of silver (gr. 1 to f^i). The colourless solution soon becomes opalescent, and when dry, leaves a white stain. Examine the stain under the microscope. Some parts of it will be found to consist of dis- tinct needles more or less thiclily interlaced. Compare the stain with that left by a drop of the test solution. It is faintly white, and shows under the microscope no distinct crystalline form. In the case of the iron-test, moisten the glass disc with a drop of liquor potassae, and after due exposure, add a drop 5f^ie fresh solution of the mixed sulphates of iron. Develop the PrussiaiTijkie by a drop of dilute hydrochloric acid. Compare with the Prussian blue the brown oxide of iron thrown down by the addition of liquor potassse to the test liquid. In the case of the sulphur-test, moisten the glass disc with the sul- phide of ammonium, allow the white stain of cyanide of ammonia to dry, and test with a drop of the perchloride of iron solution. Compare the cherry-red of the sulpho-cyanide with the yellow of the dry spot of perchloride of iron. To increase the contrast use a solution of the per- chloride diluted with distilled water so as to be nearly colourless. As the liquid in the watch-glass will have absorbed a portion of the vapour 454 HYDROCYANIC ACID. of the sulphide of ammonium, and changed to white, it should be eva- porated to dryness, and tested with the perchloride of iron. This test, as two vapours are in presence of each other, is always applicable both to the stain and to the liquid under examination. Of these four tests of prussic acid in vapour, I have found the nitrate of silver the most satisfactory. A single apple-pip bruised and moist- ened with distilled water, and placed in a watch-glass, yielded as many as twenty-two distinct reactions. The solution of nitrate of silver was rendered opalescent in every instance, and the dried stain was found to contain microscopic crystals of the cyanide of silver. The results ob- tained with the other tests in a comparative experiment, under exactly similar circumstances, were less satisfactory. Three apple-pips were bruised, moistened, and placed in three watch-glasses ; and the three tests were used in the manner already described for ten successive exposures of five minutes each. The nitrate of silver tests acted cha- racteristically in the ten experiments; the Prussian blue test succeeded in three ; and Liebig's test in one. But the liquid in the watch-glass used for this test was found to have been whitened by the sulphide of ammonium, and on being evaporated yielded a white stain, which gave a distinct and characteristic reaction with the per-salt of iron. Hydrocyanic Acid in Organic Mixtures. The acid being highly volatile, the examination of organic liquids supposed to contain it, should on no account be delayed ; and though the acid has been detected in the body after seA'eral days, the same pre- caution should be observed in reference to the post-mortem examination, and the analyses which may arise out of it. For the detection of hydrocyanic acid in compound mixtures, nitrate of silver cannot be immediately employed, as it throws down a white precipitate with hydrochloric acid, of which there is always some in the contents of the stomach, as well as with salts containing that acid, such as common salt. We must therefore resort to a process of dis- tillation. But previous to doing so, we may advantageously apply the four tests already described to the vapour given off by the organic substance. The process of distillation is to be conducted as follows : — The filtered liquid, if alkaline, is to be neutralized by sulphuric acid, which will fix any ammonia disengaged in the process of putrefaction. The mixture is then to be distilled from a water bath, at a tempera- ture of about 150°, till about an eighth part has passed over into the receiver. This distilled fluid is then to be tested by the reagents just described. It has been objected to this, and every other process in which heat is employed, that hydrocyanic acid may be formed during the distillation by the decomposition of animal matter. This is a mere conjecture, altogether unsupported by experiment. It has also been EXPERIMENTS ON ANIMALS. 455 objected that hydrocyanic acid may be formed by the processes of putrefaction and decay in various animal and vegetable matters, such as cheese and the ergot of rye. These objections are futile in all those cases in which persons are found dying or dead with the odour of prussic acid strong upon them ; and in many cases they are effectually removed by analyzing the fluid contents of other parts of the body, such as the serum contained in the brain. In a case which the author saw during his pupilage, hydrocyanic acid could be readily detected by the odour in all parts of the body, and was found in the brain by a delicate process of analysis performed by Mr. Everett. Quantitative Analysis. — Use for this purpose the precipitated cyanide of silver, every 100 grains of which correspond to 20*33 grains of the pure anhydrous acid, of which the prussic acid of the London Phar- macopoeia contains two per cent. EXPERIMENTS ON ANIMALS. Hydrocyanic acid is, in all its forms, a most active and energetic poison. Animals made to breathe air saturated with the vapour of the anhydrous acid, die instantaneously (Pereira), or in from one to ten seconds (M. Robert). In the fluid form the anhydrous acid is scarcely less rapid in its action. A single drop put into the throat of a dog killed the animal after two or three deep hurried respirations ; it caused death almost as quickly when dropped under the eyelid ; and when injected into the jugular vein, the animal fell dead at the very instant, as if struck with a cannon ball, or with lightning. (Majendie.) A single drop in the mouth of a rabbit began to act in sixty-three seconds, and killed it in eighty-three seconds ; three drops began to act on one cat in ten seconds, and on another in five seconds, killing the first in thirty seconds, and the second in forty seconds ; four drops began to act on a rabbit in twenty seconds, and killed it in thirty seconds ; and twenty-five grains, corresponding with an ounce and a half of medicinal acid, began to act on a rabbit as soon as it was poured into its mouth, and killed it outright in ten seconds at furthest. Three drops projected into the eye, acted on a cat in twenty seconds, and killed it in twenty more, and the same quantity dropped on a fresh wound in the loins, acted in forty -five seconds, and proved fatal in a hundred and five seconds. In the slower cases, there were fits of violent tetanus ; but in the very vapid cases the animals perished just as the fit began to show itself with retraction of the head. In rabbits the spine was bent back, in cats it was curved forwards. (Christison.) The concentrated acid, then, according to its quantity, and mode of administration, may begin to act on the animals usually submitted to experiment instantaneously, or in from five to sixty-three seconds, and may prove fatal in from ten to one hundred and five seconds ; when •456 HYDROCYANIC ACID. dropped into the mouth it may begin to act in from five to ten seconds, and prove fatal in from thirty to forty seconds. The effects of the dilute acid on animals have been reported by several observers ; among others by Mr. Nunneley of Leeds, to whom we are indebted for a very large an I carefully conducted series of experiments, mostly on dogs. It results from these experiments that a large dose of the dilute acid causes death as promptly as the con- centrated acid ; and that moderate dilution not only does not impair, but even somewhat enhances its effects. (Nunneley.) Large doses of the dilute acid destroy life in from two to fifteen minutes ; but life may be prolonged, after a fatal dose, for hours or even days. A dog poisoned by the dilute acid died after nineteen days of suffering. (Coullon.) When the dose is short of a fatal one, the animal is seized in one or two minutes with giddiness, weakness, salivation, and protrusion of the tongue, hurried and panting respiration, lividity of the face, and protrusion of the eyes ; with convulsions or tetanic spasms, passing into paralysis, and insensibility ; after lying in this state some time, the sensibility and power of motion are gradually restored, with slight convulsions and gasping respiration, and sometimes with powerful convulsions and loud bowlings. The animal then falls asleep, and wakes up recovered but feeble. This sleep is sometimes so profound as to resemble the effects of opium. The breath of the animal is said to smell of the poison. Several questions of obvious medico-legal importance relating to the symptoms of poisoning by prussic acid have been illustrated by experiments on animals. These will now be briefly indicated. Convulsions. — Some importance naturally attaches to the question whether convulsions are to be classed among the common symptoms of poisoning by prussic acid. This question has been answered in the affirmative. Convulsions are generally present. But there is no doubt that exceptions to the rule are not infrequent. They are re- corded by almost all who have experimented largely on animals, and large numbers of instances might easily be cited. The shriek or cry, — This too is a common, but not constant, symp- tom. It is described by Mr. Nunneley as " a peculiar cry, indicative of severe distress, different from anything heard in any other state," and as he believes " characteristic of the poison." This cry of distress has been frequently reported as absent, and in Mr. Nunneley 's nume- rous experiments on dogs was present in one half the cases. Expulsion of Fceces and Urine. — In Mr. Nunneley 's experiments, the faeces alone were passed in about a tenth of the cases ; in another tenth both faeces and urine ; in a far larger number of instances the urine alone ; and in about two fifths of the whole number neither faeces nor urine. Acts of Volition. — The dogs experimented on by Mr. Nunneley sometimes performed acts of volition before the poisonous effects showed SYMPTOMS. 457 themselves. One dog, after taking the poison, " went down three or four steps of some stairs, saw the door at the bottom was closed, and came back again ;" and another " went down, came up, and then went down again the whole flight of a steep winding staircase ;" and a third *' retained sufficient vigour to jump over one of the dogs, and then actually leaped completely across the open top of the staircase." The Post-mortem Appearances in the animals submitted to experi- ment were not well marked. The brain is generally natural in ap- pearance, though its vessels have been found turgid, and in one in- stance, in the horse, there was extravasation of blood between its external membranes. The heart and great A^essels differ in their condition and in their contents according as the death occurs quickly or slowly. In cases of sudden death, the left side of the heart is, in almost every case, perfectly empty and rigidly contracted, while the right side contains blood sometimes in large quantity. In chronic cases, both sides of the heart are distended with black blood. (Nun- ueley.) Sometimes the blood is found florid, and though usually fluid, it is sometimes found coagulated. According to Magendie the pure acid so completely destroys the irritability of the heart and voluntary muscles, that they are insensible even to the stimulus of galvanism. It appears, however, that this result was not met vvith by other ob- servers, and in Christison's experiments was not constant, occurring in some instances, but not in others. *' In eight experiments on cats and rabbits with the pure acid the heart contracted spontaneously, as well as under stimuli, for some time after death, except in the instance of the rabbit killed with twenty-five grains, and one of the cats killed by three drops applied to the tongue. In the last two the pulsation of the heart ceased with the short fit of tetanus which preceded death ; and in the rabbit, whose chest was laid open instantly after death, the heart was gorged, and its irritability utterly extinct." The lungs are sometimes empty, but more generally gorged with blood. The membrane to which the acid is applied is usually found congested. The corpse is generally very rigid. SYMPTOMS, MORBID APPEARANCES, AND TREATMENT. Symptoms. — The symptoms of poisoning by prussic acid in the human subject vary, as experiments on animals would lead us to expect, with the dose, and with the age, strength, and state of the patient. When a large dose is taken, the symptoms begin in a few seconds or minutes after the swallowing of the poison. There is probably, in all cases, a short interval of consciousness, and then a sudden access of gid- diness, rapidly followed by insensibility, deep catching respiration, and death in a short space of time. When the case is prolonged beyond a few seconds, or minutes, other symptoms are superadded. If the fatal cases and those of greater severity are thrown into one group, the symptoms may be thus briefly described : — There is insen- 458 HYDROCYANIC ACID. sibility, deep catching respiration, loud mucous rattle, cold and blue skin, dilated pupil, very rapid pulse and breathing, rigid contraction of the jaw, tetanic spasms or strong convulsions of the extremities, and, in some cases, discharges of urine and fazces. In protracted fatal cases, and in rare cases of recovery, the leading symptoms are dyspnoea, loud mucous rattle, slight convulsions, and salivation. In acute cases, the cause of death is shock, in chronic cases, suffocation. In rare instances narcotic symptoms are present as in poisoning by opium. The short interval of consciousness which, as has just been stated, probably occurs in all cases of poisoning by prussic acid, is sometimes tilled in by voluntary acts. A few persons, after swallowing large doses, have merely staggered a few steps, and sunk down without a groan, apparently lifeless, and died after a few convulsive expirations, in less than four minutes after swallowing the poison ; others have uttered expressions of fear, and then fallen as if struck by lightning. In many cases the patients were heard to fall without having uttered any sound previously. In smaller doses, the action of the poison occasions nausea, saliva- tion, followed sometimes by ulceration of the mouth, a rapid pulse, and weight and pain in the head, succeeded by a feeling of anxiety which does not pass off for several hours. Post-mortem Appearances. — The countenance is pale and composed, the eyes glistening, the venous system gorged with blood of a gUm- mering blue tint, the vessels of the brain charged with blood, with some effusion of serum into the ventricles. Traces of inflammation, or congestion, of the mucous membrane of the stomach, congestion of the lungs, and a deep blue colour of the bile, have been mentioned among the occasional post-mortem appearances. Putrefaction makes rapid progress as in most other forms of sudden death. The stomach and every part of the body exhale the odour of prussic acid. But this is not a constant phenomenon. It may be expected to be absent in cases of poisoning, where the patient survives long enough • to exhale it freely from the lungs, or where the body has been for some time exposed to the air under circumstances favourable to evaporation. It has been recognized in the stomach, and not in other parts of the body, and, on the other hand, it has been perceived in other parts of the body wheu there was no trace of it in the stomach. The odour is most conclusive when perceived in the blood or limbs ; for it has been asserted occasionally to exist in the stomach and intestines, and in the brain, where no substance containing prussic acid has been taken. Treatment : — Antidotes. Chlorine and the mixed oxides of iron are antidotes to prussic acid. The one acts by withdrawing the hydrogen of the poison, the other by forming with it the insoluble Prussian blue. But there are few cases in the human subject in which an antidote can be applied, and none in which the preparation of an antidote would not prove a loss of valuable time. In the great majority of cases the VOLUNTARY ACTS. 459 medical man is called to a suicide ali'eady dead, or m articulo mortis ; and when the patient is still alive, the jaw is so firmly closed as to render the introduction of an antidote very difficult, if not impossible. The treatment must therefore be independent of the use of antidotes. The first step to be taken is to administer the cold affusion as a shock. Water must be dashed into the face, or freely poured on the head and back. As soon as the patient is roused, though still insensible, and perhaps in convulsions, the face and trunk must be wiped dry, the clothes must be removed, and the patient be placed in bed. A sponge or rag sprinkled with ammonia, or with disinfecting fluid, may now be held to the nostrils, and the surface of the body must be kept warm by hot cloths or flannels, and by frictions with the hand or flesh-brush. As soon as the jaws can be opened, and the patient be made to swallow, an emetic of sulphate of zinc, of mustard, or of common salt should be given ; or the stomach-pump may be employed. Smallest fatal dose. — This may be stated for the adult at somewhat less than a grain of the pure acid or about 45 minims of the acid of the Pharmacopoeia. Very severe symptoms have been occasioned by about half a drachm of this acid, but recovery has taken place from doses of seventy or eighty drops. Commencement of the Symptoms. — The pei'iod at which the symptoms first show themselves is a point of considerable importance, and closely connected with the question' — What amount of voluntary motion is possible after swallowing a large dose of the poison ? There are no cases on record of that instantaneous action in the human subject which has been noted in experiments on animals. But when a large dose of the acid is taken the symptoms set in very soon, and death is very sudden. In a case reported by Hufeland a quantity of the poison equivalent to forty grains of the pure acid was taken. The man was seen to swallow the poison, was observed to stagger a few steps, and then to sink down without a groan apparently lifeless. It may be fairly assumed, then, that when the dose is very large, the symptoms manifest themselves almost instantaneously. But in the case of smaller fatal doses, or of doses productive of severe effects, a short interval elapses between the taking of the poison and the loss of sense and power. The voluntary acts which can be performed in this interval will be presently ascertained by an appeal to recorded cases. Fatal Period. — After a large dose of the poison, death appears to take place in from two to five minutes. But the poison may not prove fatal till the lapse of twenty minutes, half an hour, three quarters of an hour, or an hour. A patient of mine, to whose case allusion will presently be made, was in a very dangerous state for six hours ; and then began to recover. Voluntary Acts. — The question whether, after taking a large dose of prussic acid, the patient retains his consciousness for a time, and whether, during that interval, he is in a condition to perform certain 460 HYDROCYANIC ACID. Voluntary acts ? may become important in a medico-legal point of view. In favour ot the retention of consciousness I have the distinct statement of the patient whose case will be presently cited. That many voluntary acts may be performed in this conscious interval is proved by several recorded cases. The medico- legal import of the question will be understood from the following case. An apothecary's maid-servant at Leicester, who was pregnant by Freeman, her master's apprentice, was found dead in bed, poisoned with prussic acid. The apprentice was suspected of having been accessory to her death ; but, as it was proved that the deceased had made pre- parations for effecting a miscarriage, it was probable that she had taken the poison of her own accord. The question, whether the poisoning was suicidal or homicidal, could be answered only by a reference to the condition in which the body was found. It appealed, from the evidence, that the body lay at full length on the bed, with the head turned a little on one side, the arms crossed over the trunk, and the bed-clothes pulled smoothly up to the chin ; under the clothes, on her right side, lay a corked phial, wrapped in paper, and containing three drachms and a half of the poison. The leather and string which, had fastened the cork were found in the chamber- vessel* It was probable, therefore, that four and a half drachms of the poison had been swal- lowed ; and the question arose, Could the girl,' after swallowing this quantity of the poison, have corked the bottle, wrapped it up, and adjusted the bed-clothes? This question can be answered only by an appeal to fatal suicidal cases in which acts of volition have been performed ; or by comparing the time which such acts require for their performance, with ascertained intervals of consciousness in the human subject. The experiments on animals performed by some of the medical witnesses examined in this case, though useful as illustrations, are quite inconclusive. The following facts are recorded in illustration of the question raised in this case: — An apothecary's assistant in Germany took four ounces of the hydrocyanic acid of the Bavarian Pharmacopoeia, and was found dead in bed, with an empty two-ounce phial on each side of the bed, and the bed-covering pulled up as high as the breast, the right arm extended beneath it, and the left arm bent at the elbow. In a suicidal case reported by Mr. Newham of Bury St. Edmunds, the bed- clothes were smoothly drawn up to the shoulders ; and on a chair close to the back of the bed there was a phial with the cork in it. A third case of the same kind was communicated to Dr. A. Taylor by one of his pupils. A man found dead on the seat of a water-closet, had the bottle from which the poison was taken corked in his pocket. In a curious case of double suicide reported by Dr. Letheby, the bodies were found in positions which implied a succession of slight voluntary movements. These facts are sufficient to prove the possibility of some slight * See this case very fully reported, • Medical Gazette,' vol. viii. p. 759. VOLUNTARY ACTS. 461 voluntary efforts being made after swallowing a large dose of prussic acid ; and they must be held to justify, as far as this particular ques- tion is concerned, the verdict of acquittal pronounced in favour of Freeman. But the voluntary acts which may be performed after fatal or highly dangerous doses of this poison go much beyond those inferred from the position of the bodies in these instances. The voluntary acts may be more numerous and more considerable. In the suicidal case presently to be more minutely described a large dose of the poison was taken in bed ; but the lad was able to get out of bed, to walk round the foot of the bed to a chest of drawers at a distance of two or three yards, to place the stopper firmly in the phial, and to return to the side of the bed whence he fell senseless. In another class of cases the suicide, in addition to other movements implying volition, has been able to cry for help and even to converse. An apothecary's apprentice who had been sent from the shop to the cellar had only been a few minutes away when his companions heard him cry, in a voice of great alarm, " Hartshorn! hartshorn!" On instantly rushing down stairs, they found him lying on the lower step, grasping the lail ; and he had scarcely time to mutter, " Prussic acid !" when he expired not more than five minutes after leaving the shop. He had taken a drachm of the Bavarian acid, had tried to get at the ammonia, but had not strength to uncover the bottle. In two cases reported by Mr. Nunneley of Leeds, the patients not only moved about, but spoke and answered questions, after taking, the one a fatal, the other a large dose of the poison. The subject of the first case answered a question addressed to him some minutes after he had swallowed the poison, and the man who recovered retained the use of his speech till the jaws gradually closed. One of the most remark- able cases illustrating the power of locomotion and of speech after a fatal dose of the poison is recorded by Dr. S. C. Sewell of Montreal. A hypochondriac gentleman took seven drachms of prussic acid of the estimated strength of 3 per cent. Previous to swallowing the poison he locked himself in his room, but after about a minute unlocked the door, and cnVd out, " Come to me quick, I am dying," A servant immediately entered the room, and found him lying on his back on the sofa, with his legs crossed, insensible, and snoring. Dr. Sewell arrived in twenty minutes. He was then dead, and pre- sented the appearance of profound slumber; the legs crossed, his arms by his sides, and his eyelids firmly closed.* The effects of prussic acid when taken in a large, but not fatal, dose will be seen by the two cases which follow. The first case will be found described in the 'Revue Me'dicale ' for February 1845, the second came under my own observation in the previous year, * For more full details of some of the cases just cited, and for other cases of poisoning by hydrocyanic acid, refer to Ranking's half-yearly abstract of the Medical Science, vol. ii., p. 399. 462 HYDROCYANIC ACID. Dr. B , a physician at Rennes, having taken a teaspoonful of prussic acid, prepared by himself, in the morning, without inconve- nience, took another teaspoonful, prepared after Scheele's method, after dinner. These two doses produced no marked effect. He then took a third teaspoonful of a preparation purchased of M. Vauquelin, and after an interval of a few seconds, another teaspoonful. This new preparation tasted a little stronger than the former doses, but Dr. B remarked that " it had not hurt him." But on walking out of the shop in which he had made this last experiment, he felt an alarming kind of disturbance in his head, and on returning he uttered a few expressions of fear, and fell down as if he had been struck by lightning. The teeth were, at this time, firmly closed, there was con- tinually-increasing dyspnoea, with noisy and rattling respiration, cold- ness of the extremities, distortion of the mouth, redness and swelling of the face and neck, fixed and dilated pupil, and a pulse impercep- tible in the left, and very small in the right arm. The trismus con- tinued to inci'ease in intensity, a short and violent convulsion followed, and the abdomen, especially about the epigastrium, became rapidly distended. Attempts were now made to rouse the patient by stimu- lant frictions with ammonia and cantharides, and by stimulant appli- cations. Vomiting was also excited by tickling the throat with a feather, and some dark-coloured mucus was thrown off. After re- maining in this state for two hours and a half, he began to show signs of returning reason, and recognized those around him. The intellec- tual faculties were gradually restored, but considerable difficulty of breathing and very distinct rattle remained, with occasional expectora- tion of yellowish black mucus. During the whole of this time the breath smelt strongly of prussic acid. Dr. B was thirteen days before he could go out to see his patients, during which time the dyspnoea was frequently distressing, particularly when he turned in bed, and when he awoke in the morning. At last he quite recovered. During the first four days very little urine was passed. In the mouth of November 1844, I was called up at night to see a young gentleman who had swallowed prussic acid. The particulars of the case, as detailed by himself and his relatives, are as follows : — He is the son of a medical man, is about nineteen years of age, and studying the law. His disposition is naturally cheerful ; he has met with no disappointment, and never, until the present attempt, had contemplated suicide. His habits are temperate and industrious. On the afternoon of the day on which he swallowed the poison he dined in the Hall of one of the Inns of Court, and drank, according to his own account, half a bottle of wine— a quantity much exceeding that which he was in the habit of taking. On reaching home he was ob- served to be somewhat affected by liquor, and before going to bed went, under some pretence, into the surgery, from which he took a stoppered bottle containing, according to the estimate of his father and the apprentice, from one to two drachms of prussic acid of the Phar- CASE OF RECOVERY. 463 macoposial strength, but according to his own statement, about a mouthlul. Soon after he had gone to bed the family was startled by a noise in his room as of a heavy body falling, and a relative, who was passing at the time, was alarmed by a loud gurgling noise. His father was almost immediately on the spot, and seeing the bottle on the drawers, dashed several buckets of water over the face and chest of his son. This roused him. He was then taken into an adjoining room, and put to bed, the treatment consisting in holding ammonia to the nostrils, and applying heat to the spine and feet. An injection was also given, containing tincture of assafoetida. When I reached the house I found him in the following state, in which he had continued without alteration for three hours : — He lay on his back, drawing in his breath with great effort, each inspiration being accompanied by a loud gasping sound, and a distinct mucous rale. The pulse was upwards of 140 in a minute, and the respiration 36. The surface of the body was very cold ; the countenance was of a dull leaden hue ; the lips blue ; the pupil extremely dilated, and the jaws rigid, in which state they had remained for the whole period, so that it had been impossible to administer any antidote. The treatment fiom this time forward consisted in holding ammonia under the nostrils, assiduous frictions with the flesh-brush, and the application of heat to the surface by means, of flannels warmed at the fire, and constantly renewed. At the expiration of about five hours there was some effort to vomit, encouraged by tickling the throat, and some bloody mucus was wiped from the mouth. Soon afterwards he could be made to swallow, when some warm brandy and water and some strong coffee were given him. At this time, too, he could be made to answer in monosyllables, and could raise himself on his elbows. He was also perfectly sensible, but looked bewildered. At the end of about six hours he was sufficiently recovered to answer questions, move himself about, and call for lemonade, which he drank freely. The mucous rale had disappeared, the respiration and pulse were still frequent, the pupil was restored to nearly its usual size, and the skin was warm. Being disposed to be quiet, and seeming out of danger, he was left to himself. After a time he complained of fulness at the pit of the stomach, and asked for an emetic, which was given him, with the effect of bringing off" his stomach a large quantity of undigested food. I saw him about fourteen hours after taking the poison, and found him quite well, though weak. He gave the following distinct account of the attempt of the night before: — He was suddenly tempted, as he said, by the devil, to take prussic acid, under a confused idea that it would not hurt him. He swallowed, according to his own account, a mouthful of the acid from the bottle in bed. He then got out of bed, walked round the foot of it to a chest of drawers standing within a few yards of his bed-side, placed the stopper so firmly in the bottle that it could not be removed, and then walked back to bed, intending to get 464 HYDEOCYANIC ACID. in again. He reached the side of his bed, sat down upon it, and then lost all consciousness. During all this time he said that he had no giddiness, and no unpleasant sensation of any kind, no more than if he had talcen so much water. He also assured me, and his manner made me quite confident that he spoke the truth, that the idea of suicide had never before entered his head. The father of the lad has since informed me that the faeces, and, as he believes, the urine too, were expelled as the first effect of the poison. On examining the bottle which had contained the prussic acid, it was found quite empty, so that it was not possible to ascertain the strength of the preparation which the lad had taken. From the statement of the father and apprentice that the bottle contained one or two drachms, and that of the lad himself, who affirmed that he had swallowed a mouthful, it is highly probable that the dose taken was such as to prove fatal had it not been for the prompt application of the cold affusion, the continued use of ammonia, and the assiduous application of warmth to the surface. At the time that I first saw the patient the remedies most strongly indicated, in addition to those already employed, were warmth and friction to the surface, of which the first had been already applied, but to an insufficient extent. The extreme coldness of the suriace rendered such treatment imperative, and the blueness of the skin of the hands and face, the labouring re- spiration, and the abundant collection of mucus in the air-passages, furnished an additional reason for its assiduous application. Friction and warmth to the surface are as strongly indicated, after the patient has been in some degree roused from the' first effect of the poison, as the cold affusion at the onset. This case is especially interesting as showing the interval of perfect consciousness and complete command of the voluntary muscles which may intervene between the swallowing of a large dose of prussic acid and the development of the characteristic effects of the poison ; and it is a very striking example of a large class of cases of suicide in which the impulse to the commission of the act precedes the act itself by a very short interval, and springs up during a temporary excitement of the'mind. I have every reason to believe that the account which the lad gave me of the act itself, and of the sudden impulse which led to it was perfectly correct. His narration had all the appearance of open- ness and truth. Three medico-legal questions which have been raised in cases of poisoning by prussic acid have still to be considered. To two of these questions some importance was attached in the case of Sarah Hart, the victim of Tawell. 1. Is there, in cases of poisoning by prussic acid, any death-cry or scream which would serve to announce the ojieration of the poison ? 2. Are convulsions of common or of universal occur- rence ?3js prussic acid a cumulative poison? 1. In answer to the first question it may be stated that a patient who is conscious of having swallowed the poison may call out for assistance ; but the plaintive cry CYANIDE OF POTASSIUM. 465 ov louder scieam, sometimes heard in animals has not yet been recorded in any case of poisoning in man. 2. It is probable that convulsions are not of more frequent occurrence in poisoning by prussic acid than in other cases of sudden death. The expulsion of the urine and fasces, which has been observed in certain cases, was probably accompanied in those cases by shoit convulsions, and in some instances (as in a case reported by Mr. Hicks) there have been muscular efforts expressive of intense anxiety and urgent want of breath ; but the delibe)-ation which has characterized the few movements of the patient, and the calm and easy attitude of the dead body in almost every instance show that con- vulsions aie either absent altogether or short and transient. 3. The question of the cumulative property of prussic acid is sometimes raised when a patient dies while taking a series of medicinal doses ol the acid at such short intervals of time as a few hours. It is deemed piobable that the previous doses have not been eliminated from the system, or spent their effect upon it, and that the addition of the last dose determines the Altai result. In the case of so volatile a poison, and one so readily eliminated by the lungs as well as by other organs of the body, it seems highly improbable that a medicinal dose, which is geneially but a small fraction of the smallest fatal dose, or even a series of medicinal doses, would leave such a residual effect as to prove fatal to life on the addition of another medicinal dose. But doses that exceed the proper medicinal limit may happen to prove fatal, though similar previous doses have appeared to be hai mless, in conse- quence of a change in the state of the body itself ; for there is no doubt that the line which divides a harmless from a fatal dose is not verv wide. Fortunately this question, so difficult of solution, is not one of great practical importance. POISONING BY THE CYANIDES. The cyanides of potassium and of mercury have proved poisonous, the latter with symptoms allied to those of poisoning by corrosive sub- limate (see p. 419). the former with symptoms of poisoning by the acid itself. Cyanide of Potassium. — This substance is now largely used in tf.e arts, both in the process of electrotyping and in that of photography. It is employed to remove the stains of nitrate of silver from the hands, and to clean tarnished metal and gold and silver lace. Properties. — This salt is sold as a white crystal or crystalline mass, which readily absorbs moisture, gives out a strong odour of prussic acid, and has a characteristic cold, bitter, pungent taste. It is very soluble in water ; and its solution has a strong alkaline reaction. Tests: — a. On the addition of an acid, the vapour of prussic acid is given off, which may be -identified by its odour, and by the tests described at p. 453. 6. It yields with a solution of nitrate of silver the white cyanide of silver, c. A solution of chloride of platinum throws 2h 4:66 HYDROCYANIC ACID. down the base. d. The liquid tests produce with tlie solution the reactions described at p. 452 ; but as the solution already contains potash, ihe addition of liquor potassae is not required. In organic liquids the poison may be detected by neutralizing the base with sulphuric acid, and immediately distilling over the prussic acid. Si/mptoms. — This substance acts neaily with the rapidity and violence of prussic acid itself, and produces symptoms differing so little from those proper to the acid as to require no separate description. Fatal Dose. — Less than five grains. From the composition of the cyanide, which contains nearly forty per cent, of the anhydrous acid, it is probable that about 2^ grains of this salt would destroy life. Post-mortem Appearances. — Those proper to poisoning by prussic acid. Treatment. — That of poisoning by prussic acid itself. As the cyanide of potassium is a strong local irritant, it should be applied to the hands to remove stains with caution, and used with similar care for manufacturing purposes. 3. VEGETABLE SUBSTANCES AND PRODUCTS CONTAINING, OR . YIELDING, HYDROCYANIC ACID. The leaves, seeds, or roots of several plants either contain prussic acid, or they yield it when bruised and moistened. The bitter almond, the kernels of the chei ry, plum, and peach, and the pips of the appie, are examples of poisonous seeds; the leaves of the cheriy- laurel yield the poison on distillation, and the plant which yields tapioca (the latropha manihot, or cassava) contains prussic acid in the juice of the root. The bitter almond, and the oil and water obtained from it, and the distilled water from the cherry laurel, are particularly deserving of notice. The bitter almond is distinguished, as its name implies, by its bitter taste. It forms with water a white emulsion, in which the essential oil blended with prussic acid is rapidly developed by the nuitual action of two of its constituents, emulsine and amygdaline. The A^apour from the emulsion acts characteristically with the tests for prussic acid. As the same change takes place in the stomach, bitter almonds cannot be eaten in large numbers without inducing symptoms of poisoning. The same result follows from eating the hitter almond cake, which remains after the expression of the fixed oil. But the essential oil, its alcoholic solution (almond flavouring), and bitter almond water, are active poisons, and have proved fatal. , Of these three preparations the essential oil is by far the most important, as it is a very active, and has now become a very favourite, poison. Essence or Oil of Bitter Almonds. — This is the product of the distil- lation of the pulp or emulsion of the bitter almond. It contains, in addi- tion to hydrocyanic acid, hydride of benzole, benzoin, and benzoic acid. The hydrocyanic acid, to which it chiefly owes its poisonous properties, may be separated from it, and the essence thus purified, and rendered OIL OF BITTER ALMONDS. 467 comparatively liarailess, is sold for culinary purposes. The essence, or oil, pveAnous to this separation, contains from 8^ to l4j per cent, of the anhydrous acid. It has, therefore, fiom four to seven times the strength of the acid of the Pharmacopoiia. A liquid variously known as almond flavour, spirit of almonds, or essence of peach kernels, consists of the oil dissolved in seven or eight times its quantity of spirit. Properties. — Ordinary specimens of the oil have the colour of amber, a peculiar, pungent odour, due in part to the prussic acid which it contains, and a bitter, aromatic taste. It is heavier than water, which dissolves only a small fraction of it; but it is soluble in alcohol and aether. It produces a greasy stain on paper, and it has a slight acid reaction. Strong sulphuric acid reddens it. Tests. — Those of hydrocyanic acid. Pour a drop of the oil into a series of watch glasses, add a few drops of distilled water, and invert over them discs of glass moistened with the several tests (p. 453), The vapour acts more promptly when the glasses are warmed. Or, place a few drops of the oil in a test-tube, add a drachm of distilled water, mix them well by shaking ; pour the mixture on a wet filter, and test the liquid that passes through as for dilute hydrocyanic acid. The odour of the oil is not a decisive proof, since a chemical compound known as nitro-benzole or nitro-benzine has a very smiilar odour. Symptoms. — Those of poisoning by hydrocyanic acid (p. 457) ; but the symptoms do not appear to commence so soon, and the duration of the poisoning seems to be longer. The recorded cases pi-esent similar variety in the symptoms, and similar acts of volition occupy the inter- val between the swallowing of the poison and the commencement of the symptoms. Post-mortem Appearances.-^-Those of poisoning by hydrocyanic acid (p. 458), the odour of the oil taking the place of the odour of the acid. Treatment. — That of poisoning by hydrocyanic acid (p. 458). Fata! Dose. — About twenty drops. As strong specimens of the oil have from four to seven times the strength of the hydrocyanic acid of the Pharmacopeia, and a less quantity of the acid than fifty minims has proved fatal, it is probable that as small a quantity as ten or twelve drops might destroy the life of an adult. Duration. — From a few minutes to half an hour. It may destroy life as speedily as prussic acid itself. Bitter-almond Water. — This water is distilled from the cake left after expressing the fixed oil from the bitter almond. It is found in the shops of very variable strength, and is quite unfit for medicinal uses. Some specimens are found to contain one per cent., others a quarter per cent. It owes its poisonous property to the prussic acid which it contains ; and responds to the tests for that poison (p. 452). The symptoms, post-mortem appearances, and treatment aie those of poisoning by hydrocyanic acid (p. 457), 468 HYDROCYANIC ACID. Laurel Water. — The leaves of the cherry laurel (Prunus lauro- cerasus) yield both a distilled water and an essential oil which have the same properties as the water and oil of bitter almonds, and wei-o formerly employed for the same purposes. The quantity of the prussic acid in the distilled water is about a quarter per cent., and in the essential oil three and a quarter per cent. Other portions of the plant also yield the poison ; but it is not contained in the pulp of the fruit. The cherry laurel water has proved fatal in more than one case ; but the one which possesses the greatest interest is that of Sir Theodosius Boughton, poisoned by Captain Donellan in 1781. Sir Theodosius Boughton, a healthy young man of twenty years of age, was in the habit of taking a laxative draught from the hands of his mother. On the morning of his death she observed, while giving him his draught, that it had a strong smell of bitter almonds. ♦* Two minutes after he took it she observed a rattling or gurgling in his stomach; in ten minutes more he seemed inclined to dose, and in five minutes afterwards she found him quite insensible, with the eyes fixed upwards, the teeth locked, froth running out of his mouth, and a great heaving at his stomach, and gurgling in his throat. He died within half an hour after swallowing the draught." The body was carelessly inspected ten days after death, but the post-mortem appear- ances threw no light on the cause of death. The odour of the draught, the rapid occurrence of symptoms so closely resembling those present in recorded cases of poisoning by prussic acid, and the speedy death of tlic sufferer at an age when apoplexy is so rare, combine to leave no reason- able doubt of the i eal cause of death. 469 CHAPTER XV. POISONING BY ALCOHOL, iETHER, AND CHLOROFORM. These poisons have the common property of inducing a state of nar- cotism, often preceded by delirious excitement, and followed by indis- position, of which nausea and vomiting are generally the leading symp- toms. In large doses, and in a concentrated form, tliey may destroy life suddenly by shock ; but they generally prove fatal by inducing a state allied to apoplexy, or by paralyzing the heai t. They act as irri- tants to the parts with whiclv they come in contact, producing intense inflammation in the lining membrane of the stomach when swallowed, and in the lining membranes of the air-passages when inhaled. But they do not affect the whole tract of the intestinal canal, as do the poisons grouped under the class of narcotico-irritants, 1. ALCOHOL. Alcohol, or spirit of wine, is the active ingredient of a great variety of intoxicating agents obtained from saccharine juices in a state of fer- mentation. By the distillation of such fluids, followed by rectification with charcoal, and a final distillation from quick-lime, anhydrous or absolute alcohol is obtained. This absolute alcohol, diluted with little more than its weight of water, constitutes proof spirit, which differs little in strength from the various ardent spirits distilled from wine, malt, molasses, or rice, flavoured and coloured with burnt sugar, juniper berries, and peat, and known respectively as brandy, whiskey, hollands or gin, rum, and arrack. The absolute alcohol in these ardent spirits varies from 51 to 54 per cent. Of the stronger wines it constitutes from 12 to 17 per cent. ; of the lighter wines from 7 to 9 per cent., and of the stronger English malt liquors from 5 to 6 per cent. Properties. — Pure alcohol is a colourless, volatile liquid of low specific gravity (0-&15 at 32^), boiling at 173^, and not freezing at the lowest attainable temperature. It has an agreeable odour, and a burning, pungent taste. It is very inflammable, burns \yith a light- blue flame, and yields, as the products of its combustion, carbonic acid and water. Tests. — a. When burned, it leaves no stain of charcoal. 6. The products of combustion render lime-water or the solution of nitrate of baryta white and turbid, c. It dissolves camphor, d. When boiled with a saturated solution of bichromate of potash, mixed with sulphuric 470 ALCOHOL. acid, i he green oxide of chrome is set free. This last test is recom- mended by Dr. Taylor (* On Poisons,' p. 728) as one of great delicacy ; but it doesjiot distinguish pure alcohol from aether or pyroxylic spirit. In Organic Liquids.— The contents of the stomach in prsons dying from the effects of large doses of spirituous liquors generally have the odour of the spirit ; but there are exceptions to this rule. If they contain any spirit it may be separated by submitting them to the same procesvS of distillation as is adopted in order to obtain anhydrous or absolute alcohol from fermenting sacchai-ine substances. If the con- tents of the stomach have an acid reaction, they must first be neu- tralized by potash. The liquid resulting from the distillation may be identified by the tests just enumerated. Alcohol is absorbed, and may be detected by its odour, and by tests apphed to the products of distillation, in the blood and secretions, in the brain, and in other solid viscera. Experiments on Animals. — From Sir Benjamin Brodie's experi- ments on rabbits with large quantities of proof spirits, it appears that symptoms of poisoning set in immediately or in a few minutes, and that death ensues in from about half an hour to an hour and a quarter. In one experiment in which two ounces of proof spirit were injected into the stomach of a rabbit, the injection was scarcely completed when the animal became perfectly insensible. It was apparently dead in twenty-seven minutes, but the heart had not ceased to beat. The symptoms produced in these experiments were complete insen- sibility, dilatation of the pupils, rapid pulse, laborious and stertorous breathing, and slight convulsions. The lining membrane of the stomach bore marks of great inflammation. M SYMPTOMS, MORBID APPEARANCES, AND TREATMENT. Symptoms. — After a period varying from a few minutes to an hour or more, according to the quantity and strength of the alcoholic liquid, the symptoms set in with confusion of thought, giddiness, imperfect or double vision, indistinct and stammering speech, uncertain and abrupt movements of the limbs, and a tottering and stumbling gait. At length the patient becomes speechless, motionless, and insensible, with a bloated and suffused countenance, injected eye, dilated and fixed pupil, livid lip, and slow and stertorous breathing. Recovery may take place after a prolonged sleep, or more abruptly by vomiting ; or death may occur after an interval of several hours with symptoms of collapse, indicated by pallor of the face, cold sweats, quick and feeble pulse, and complete relaxation of the limb>. When very large quantities of ardent spirits are taken death may ensue almost immediately by shock. Sometimes insensibility sets in suddenly ; sometimes as a sudden relapse after apparent recovery. Convulsions are among the occasional symptoms, and delirium tremens and raging incoherence are some- times the result of a single debauch. The symptoms of poisoning by tEther. 471 alcohol nearly resemble, as has been shown by Sir Benjamin Brodie, tliose of concussion of the brain ; they are also difficult to distinguish troni the effects of severe cold and from those of poisoning by opium. In many cases the odour ot spirits will assist the diagnosis. As a -t'lieral rule, the pupils are dilated in poisoning by alcohol, and con- tracted in poisoning by opium, and the countenance which is flushed in the one case is pallid in the other. Morbid Appearances. — The most constant appearance is a deep crimson or dusky red colour of the lining membrane of the stomach, sometimes extending upwards to the gullet and downwards to the com- mencement of the small intestines. In some cases there is dark extra- vasation under the lining membrane. In rare instances the stomach is inflamed only in patches : still less frequently there are no marks of inflammation in any part of the organ. Congestion cf the brain, and of the air-passages, are among the less constant appearances. Treatment.— The stomach-pump s?iould be used without delay, and the cold affusion as a shock. The after treatment will depend on the state of the patient. If there is much congestion of the brain, blood may be drawn from the arm. If great difficulty of breathing, with a cold surfiace and feeble pulse, the treatment proper to apticea may be required. In the last resort, galvanism may be employed. Chronic Poisoning by Alcohol. — Drunkards suffer from functional and organic diseases of all the important organs of the economy : from indigestion, with vomiting and purging through irritation of the stomach and bowels ; from jaundice through irritation of the liver ; ftom albuminous urine, diabetes, and other urinary disorders through irritation of the kidney ; from congestion of the brain, delirium tremens (see p. 159), and insanity; from paralysis, convulsions, and shaking palsy ; as the effect of the poison on the nervous centres. The organic diseases induced by the prolonged abuse of spirituous liquors are fatty degeneration of the liver, kidneys, heart, brain, and spinal cord, scirrhus of the stomach, and pulmonary consumption. Dropsy is a common result of the organic diseases of the drunkard. 2. .ETHER. Several volatile and inflammable liquids are known to the chemist under the general name of CBther, and they are divided into three groups undei' the titles of simple, double, and compound aethers. The liquid known as aether, ordinary aether, vinic ather, or sulphuric asther, belongs to the class of simple aethei-s, and is the poison here spoken of. It is the product of the distillation of a mixture of alcohol and sulphuric acid. Properties. — Pure aether is a colourless liquid, highly volatile and inflammable, with a low specific gravity (0'724 at 55^), boiling at 95'-' and freezing at about — 24<^. It burns with a yellow flame, and deposits charcoal on cooled surfaces, but when burned with a proper proportion 472 .ETHER. of oxygen is resolved (like alcohol) into carbonic acid and water. It yields a \viug appearances : the large veins and the right cavities of the heart are gorged with black blood, and the lungs and lining membrane of the air-passages are congested. The brain and its membranes are injected, ami the veins and sinuses distended. Serum is found in the ventricles, ainl at the base ; and effusions of blood on the surface of the brain or into the ventricles are of occasional occurrence. The base of the tongue IS injected, and ecchymosed patches are sometimes found in the alimen- tary canal. Some of these appearances bear a close resemblance to those present in cases of death by apnoea, but the turgescence of the brain is much more remarkable in cases of poisoning by carbonic acid than in fatal cases of apnoea from other causes ; and it has been proved experimentally that oar i ionic acid gas does not act as a mere asphyxiating agent, but as a . sj)<»oific narcotic poison.* * As the value of some of the post-moriem appearances was a subject of lively controversy in the case of James Trickey, given in tlie text, the follow- iiiu particulars are subjoined from a valuable paper by the late Dr. Gelding l>inl —Q Guy's tlospital Reports,' vol. viil. p. 75.) i'lie expression of countenance in twelve cases in whicli it is described, was pall' and calm in 5 cases; bloated in 7. Vomiting had occurred in 3 cases, and was absent in 5 in which that symptom was noticed. There was froth at the mouth in 6 cases ; it was absent in 4. There was froth and serum at the nos- trils in 4, and they were lined with black mucus in 2. The eyes were injected in 2 ; dilated, prominent, and shining in 3 ; closed and dull in 3. The limbs were rigid in 5 ; flexible in 2. The tongue was protruded and grasped by the teeth in 6 ; drawn in and concealed in 2. There were livid patches on the skin in 10 cases ; they were absent in 2. The abdomen was distended with air in 9 ; not distended in 4. The membranes of the brain were injected with blood in 8, and described as congested in 4 ; there was serous effusion beneath the arachnoid in 3. The vessels and sinuses were turgid in all the cases in which those parts are mentioned. The blood was not always of the same colour. There 478 POISONING BY NARCOTIC GASES. Treatment. — This consists in the prompt removal of the patient pure air, the use of cold affusion as a shock, and, where the count© nance is bloated and livid, of general or local blood-letting. Artifici respiration, galvanism, and the inhalation of oxygen gas may beresorte to in extreme cases. Frictions and warmth to the sui-face are indicated as in cases of apnoea. • Preventive Measures. — The prevention of accidental poisoning b; carbonic acid must rest in a great degree on the possession on the jiar of the public of correct information respecting the nature of combustioi and of its products, and of the situations in which accumulations carboni(! acid gas are most likely to take place. The fact that stove heated by charcoal in the open air of rooms, and giving out carbon! acid into the atmosphere, are still used by persons of education, show how little scientific knowledge such persons may possess. It may b well, when speaking of preventive measures, to correct an error in which even intelligent and educated persons are liable to fell, that it i safe to breathe an atmosphere in which a candle continues to burn It should, on the contrary, be understood that a candle may burn in atmosphere which will speedily prove fatal to life; while, on the othe hand, a man may for a short time breathe with impunity an atmospher in which candles are extinguished. Thus, Mr. Coathupe cites a cas( that occurred in his own neighbourhood, of a man who descended int< an abandoned coal-pit, in which ignited candles were repeatedly extin- guished, and remained in it for several minutes, until he succeeded il bringing to light the body of a child, who had fallen from a part o! the old machinery. In a case mentioned by M. Marye, and quoted by Devergie, a candl< was extinguished in an atmosphere that produced only a slight sensa tion of uneasiness in a gentleman who made an abortive attempt suicide. In another and successful attempt, a candle was found burn ing on the table, whilst he was lying dead on the floor. In the forme instance, the candle was probably below the level of the body, in th< latter it was above it. (' Annales d'Hygiene,' vol. xxiii. p. 190.) Several interesting and practically important questions connecte< with poisoning by carbonic acid require examination. Some of th are set forth in the following case, which, at the time of its occurrence excited a lively interest, and gave rise to much discussion. James Trickey, aged QQ, watchman and steeple-keeper of St was no effusion of serum on the brain in 6 cases. Serous effusions in 3 cases The substance of the brain was injected in 8, Blood was effused on the surfao in 1 ; the brain was in its natural condition in 2. Serum in the ventricles oj the brain in 6 ; absent in 3. Blood was effused into them In one case. Among the post-mortem appearances on whicli the greatest stress has beei laid is the rosy or livid discoloration of the skin. Devergie places great relian« upon this sign. The long continuance of animal heat, and rigidity, and th( slow progress of putrefaction, are also points which have been much Insistec on. (' Annales d'Hygiene,' vol. xvii. p. 225.) CARBONIC ACID GAS. 479 Michael's Church, Comihill, was placed in the church, on the night of Nov. 17, 1838, in charge of a stove heated by charcoal (one of Har- ]ior and Joyce's patent apparatus). He entered the church at eleven ■I'dock' at night, and the next morning he was found dead, lying on his face, with his feet about three feet from the stove, and his head lower than the rest of his body, the trunk resting on a step. A con- r>i(lerable quantity of vomited food was found on the floor near his mouth. The church was so full of some vapour that the respiration ot' the persons who first entered in the morning was considerably af- fected. The principal post-mortem appearances were as follows : The countenance calm and composed, and the eyes lustrous. The vessels of the brain gorged with fluid blood ; considerable serous effusion between the arachnoid and pia mater, and at the base of the brain ; numerous bloody points in the substance of the brain. The lungs ahnost black, the vessels turgid with blood, the trachea containing a frotliy mucus, and the lining membrane injected ; the blood in the large veins dark, but fluid; the stomach nearly full of undigested food. Every other part of the body healthy. At the inquest, considerable difference of opinion existed among the medical witnesses as to the cause of death. They all agreed that he li id died of apoplexy, but some thought this mode of death was suffi- ciently explained by his advanced age, by his apoplectic make, and by the full meal which he had taken before he commenced his watch in the church. Others, on the contrary, though they likewise attributed tlie death to apoplexy, attributed the apoplexy itself to the inhalation of carbonic acid. The question to be decided, therefore, ultimately took this shape : Was there a sufficient quantity of carbonic acid in the church to ac- count for the man's death; and supposing the quantity diffused through the church not to be sufficient to account for the fatal event, might not the part in which he lay (for he was on the floor close to tlie stove) contain a sufficient quantity of the gas to prove fatal? As similar cases, involving similar questions, may again arise, it may be well to say a few words on each of these two points. 1. What is the smallest quantity of carbonic acid diffused through the air that may prove fatal ? 2. Is the carbonic acid produced in the burning of fuel in rooms or buildings equally diffused, or does it accumulate in one part of the apartment more than in another ? 1. In estimating the quantity of carbonic acid required to destroy life, it ought to be borne in mind that when the gas is the product of respiration or combustion it is formed at the expense of the oxygen of Uie air ; so that the air is rendered less fit for the support of life by the withdrawal of a vital element, as well as by the addition of a poison. The different susceptibility of persons of the two sexes and different ages should also be considered (see p. 227). Some light is thrown on this question by the experiments of Allen and Pepys, which 480 POISONING BY NARCOTIC GASES. have shown that air once inspired becomes charged with from 8 to 8 per cent, of carbonic acid, and that, however often it may be respired it never acquires more than 10 per cent. As fatal consequences hav more than once ensued from simple overcrowding, when the pollutio of the air, in all probability, fell far short of this limit, we may safely assume that a quantity of carbonic acid much less considerable would destroy life. Devergie thinks that five per cent, is sutficient, but Mr Coathupe (' Lancet,' vol. xxxi. p. 201) states that he suffered most severely from inhaling an atmosphere containing, at the outside,! according to his own calculation, 2 per cent. In the case of St. Michael's Church, it appears that the contents o: the building were 110,000 cubic feet, and the quantity of carbon! acid which might have arisen from the charcoal employed was 150' cubic feet; so that little more than 1^ per cent, of the gas could hav been diffused through the building, a quantity probably much smaller than that contained in crowded and ill-ventilated looms, especially when lighted by gas, and probably too small to destroy life, though breathed by a sleeping man for several hours in succession. The death of James Trickey could not therefore be attributed to the inhalation of carbonic acid, on the supposition that the gas is uniformly diffused through the air of the building. But if. as some believe, and as the ex- peiiments of Devergie seem to prove,* the carbonic acid is unequally distributed, and, when the temperature of the apaitment has become the same in every part of it, subsides to the floor, the death of James Trickey, who lay on the floor of the church witiiin three feet of the stove, was probably due to the poisonous gas which he inhaled. But in order to explain the death of James Trickey by carbonic acid, it is not necessary to assume this subsidence of the gas to the lower part of the building; for except in those cases in which this heated gas given off from the burning fuel rises in a column of air to escape by a vent in the ceiling directly above it, the gas will doubtless bs, diffused in larger quantity through the air immediately surrounding the stove, whether above it, around it, or beneath it ; and if the air of the apartr ment, instead of being assumed to be still, is subject to drafts, the gas would be carried in the direction of the draft, so as to increase the danger of a person exposed to it. If the draft, however, be strong, it will clear the air of the carbonic acid which it contains, and free those who may happen to be in the cuiTeut from all danger. This circum- stance is illustrated by a case reported by Dr. Golding Bird, which also seems to place, beyond all i-easonable doubt, the greater imme- diate accumulation of air in the proximity of the stove, than in the remoter parts of an apartment. This subject requires, and would well rejiay a careful investigation.! * These experiments deriye some confimiation from a case quoted by Devergie from a work \-' j-esorted to until the stomach has been emptied by emetics or the Ntumach-pump. Hitherto the group of narcotico-acrids has been treated as consisting oi individual poisons having certain characters in common. It is now uGcessaiy to deal with this group, as has been done already with the irritants and narcotics, as consisting of certain subordinate groups characterized by certain symptoms in common. One well-defined class consists of the plants which yield strychnia as their active prin- ciple— a class characterized by the powerful effect produced on the reflex function of the nerves of voluntary motion and sensation, in the shape of tetanic spasm, and heightened sensibility of the surface. The mind is generally unaffected. A second class is characterized by the very geneial occurrence of delirium, and illusions of the senses, asso- ciated with great dilatation of the pupil. This class comprises belladonna, hyoscyamus, stramonium, and camphor. A third class is equally characterized by the general occurrence of syncope or collapse, without delirium. This class comprises aconite, digitalis, tobacco, lobelia inflata, and hemlock ; and in this class, too, the mind is usually unaffected. The remaining members of the class are chiefly remark- able for occasioning violent irritation of the alimentary canal with nervous symptoms not sufficiently defined or ascertained to justify their admission into the three classes just described. The following classification of the narcotico-irritants will be adopted : — 1. Strychnia and the plants which yield it. 2. Belladonna, hyoscyamus, stramonium, and camphor, with the oenanthe crocata, cocculus indicus, lolium temulentum, and poisonous mushrooms. 3. Aconite, digitalis, tobacco, lobelia inflata, and hemlock. 4. The ergot of rye, cicuta virosa, phellandrium aquaticum^thusa ^ . cynapium, cytisus laburnum, and solanum nigrum. /*-A^x»^ ^a^^S^**^ 5. Oil of turpentine, kreasote, oil of tar, and oil of dippel. 488 CHAPTKR XVIII. NUX VOMICA AXD STRYCHNIA. The alkaloid strychnia is the chief active ingredient in several plan' which have the common property of giving rise to symptoms similar to those of tetanus. It is generally found with another alkaloid, brucia possessed of similar, but less active, poisonous properties. Strychnia is ascertained to be the active poisonous principle of five plants — the Strychnos nnx vomica, S. Ignatia, S. tieute', S. toxifera, and S. colubrina. All these plants are natives of hot climates. The Strychnos nux vomica grows as a tree in Coromandel, in other parts of India, and in Ceylon ; the S, Ignatia in the Philippine islands, also as a tree ; the S. tieute in Java, as a large climbing shrub ; the S. toxifera is a native of Guiana ; and the S. colubrina grows as a tree in many parts of Asia. The S. nux vomica yields the poisonous seed and baik in use in this country ; the S. Ignatia produces the seed known as the bean of St.' Ignatius; the S. tieute supplies the bark of which an aqueous extract constitutes theiipas poison ; the S. toxifera was until lately the reputed source of the poison variously designated as woorara, woorali, oorara, cui-ara, and ticunas, and used by the natives of South America in preparing their poisoned arrows. Theie is now reason to believe that this poison is a compound derived from several sources (animal and vegetable). The curara as thus prepared, as well as the upas antiar (from the Japanese tree the Antiaris toxicaria), and the poison nut of Madagascar (the produce of the Tanghinia venenifera) act on the heart and brain, and not on the spinal cord. For more minute details respecting these poisons, the reader is referred to works on Toxicology. There are three vegetable productions more or less common in England which contain strychnia — the bean of St. Ignatius, and the bark and seed of the Strychnos nux vomica. The beans of St. Ignatius are not often met with out of museums. They are the seeds of the pear-shaped fruit of the S. Ignatia, in which they exist to the number of about twenty. They vary in size from that of a nut to that of a large filbert. They have a thin brown outer coat, which is easily detached, and leaves a smooth, black sur- face. They are very hard, and have the appearance of small pebbles with irregular shaped and rounded outline, and two or three unequal flat- tened surfaces. They contain strychnia in the proportion of 12 parts in 1000, and some brucia, and produce the same effects as nux vomica or strychnia. NUX VOMICA. 489 The hark of the Strychnos nux vomica, formerly mistaken for cusparia or angostura bark, and named, accordingly, ' false Angostura bark,' has a very characteristic appearance. It is quilled, or twisted like dried horn, and is thickly covered with white prominent spots bearing some resemblance to a lichen. It yields a light yellow powder, which has an intensely bitter taste, and is reddened by nitric acid, it contains both Ntiychnia and brucia, and acts upon the system in the same manner as the seed or the alkaloid. The nux vomica, or seed of the S. nux vomica, is much more im- portant than the foregoing, and requires to be more minutely tloscribed. NUX VOMICA. This poisonous seed is imported into this country in large quanti- ties ; and the seed itself, a powder prepared from it, and a spirituous extract (the extractum nucis vomicae of the London and Edinburgh Pharmacopoeias), as well as the alkaloid strychnia and its salts, are in common use as a poison for wild animals, rats, and vermin ; and it is prescribed as a medicine in paralytic affections, and in some other diseases to which it would seem less applicable. In the two years 1837-8, nux vomica was the cause of death in three instances. These seeds are enclosed in a rich orange-coloured fruit of the size and shape of a large apple, each fruit containing ft-om three to five seeds. The seeds are circular in outline, vary in size and thickness from that of a shilling to that of a florin, and weigh from less than one scruple to more than two scruples. Their edges are rounded ; one surface is concave, and the other convex, or convex in the centre and deeply grooved near the margin as in fig. 54. A horizontal section has the appearance shown in fig, 55, and a vertical section displays a circular Fig. 54. Fig. 55. Fig. 56. central cavity and heart-shaped embryo, as in fig. 56. By introducing a sharp knife at the projecting point shown in rig. 54, the seed may be easily cleft in two so as to display the embryo. The seeds have an external coating of liglit brown silky hai)'s, radiating from the centre, but the bulk of the seed is white, or of a light slate colour, and has a waxy appearance. The texture of the seeds is so hard that it can only be reduced to powder by rasping or filing. When turned in the 490 NUX VOMICA AND STRYCHNIA. lathe they yield a white shaving like hartshorn. The interior poili of the seeds assumes a rich orange colour when touched with nitrie acid, and is tinged green by the perchloride of iron. The powder of the seeds has the colour of jalap powder, a faint odour, and an intense and persistent bitter taste. The brown silky fibres which tbinm the coating of the nut are seen in large numbers under the microscope, and are very distinctly defined when treated Fig. 57. ^vith a drop of strong nitric acid. They have the appearance shown in fig. 57. Its watery solution is ^ rendered pink by nitric acid, and green by the per- d^f/^DS chloride of iron. The powdt-r contains the alkaloids ^<*^li strychnia and brucia in union with strychnic or igasuric acid. The quantity of the alkaloid strychnia has been variously estimated at 4 and at 10 parts in the 1000. The extract of nux vomica is readily recognized by the rich orange colour imparted by nitric acid, the lake colour developed by sulphuric acid, and the transient blue tint given by sulphuric acid and bichromate of potash. Symptoms. — Those of poisoning by strychnia. Post-mortem Appearances. — Those of poisoning by strychnia. The brown powder often adhei'es to the lining membrane of the stomach. Treatment. — The poison to be removed by emetics or the stomach- pump. The rest of the treatment that of poisoning by strychnia. Fatal Dose. — Thirty grains of the powder, or the weight of a nut of medium size, and three grains of the alcoholic extract, have pioved fatal. Commencement of Symptoms. — From ten to foity minutes, or an hour. Fatal Period. — From fifteen minutes to three hours or more. One hour is a common period. STRYCHNIA. This alkaloid is now in very general use in every part of the world for the destruction of wild animals and veimin. in poisoning wild animals it is usual to insert the strychnia into the stomach of a small animal or bird recently killed ; and in poisoning birds, to steep grains of wheat in a strong solution of the alkaloid, or of one of its salts. A powder known as " Battle's Vermin Killer " contains, according to an analysis by Dr. Letheby, 23 per cent, of the poison mixed with flour, sugar, and Prussian blue. The flesh of animals that have eaten or poisoned meat or grain sometimes proves poisonous to other animals. \ Strychnia and its salts are also used as medicines, and in consequen«? of this twofold use, cases of accidental poisoning occasionally occur. Of late yeai-s, too, the alkaloid has become a formidable instrum.ent of death in the hands of the murderer ; and is believed to have been the immediate cause of death in more than one recent instance, as in the cases of Palmer and Dove. POISONING BY STRYCHNIA. 491 Fi'om the Report of the Registrar-General it appears that on an r.-erage of the five years 1852-56 strychnia and nuxvomicaare credite<^l with 2 out of the 268 deaths by ascertained poisons. Strychnia may have to be examined, 1. in substance, 2. in solution, '!. in organic substances. 1. In Substance. Properties. — Strychnia is found in commerce either as a white powder, or as a colourless crystal. In commercial specimens the form of the crystal is a rectangular prism, either of the exact shape shown in fig. 58, or with the ends replaced by one or two oblique jilanes. The crystals of strychnia, when obtained from solutions of its salts by the addition of liquor am- monia3, or, still better, by exposure to its vapour, present under the lens or microscope three leading forms — the long rectangular prism, the short hexagonal prism, or the regular octahedron. From a group of crystals obtained by exposing a drop of a solution of the acetate of strychnia to tlie vapour of ammonia, the forms shown in figs. 59 and 60 have been selected.* The crystals in fig. 69 are long four-sided Fig. 58. \ \ ^, \; Fig. 59. Fig. 60. prisms, isolated or in stellate groups, with a single octahedron shown in contact with one of the prisms. The crystals in fig. 60 are either regular octahedra or modifications of the same, or short six-sided prisms. One or two of the crystals appear to be dodecahedra. The octahedra will be recognized in the several points of view in which they present themselves, on referring to the account given of the crystals of arscnious acid at p. 372. Strychnia has an intensely bitter and very persistent taste, which is slated to be distinctly perceptible in solutions containing one grain of Acetate of morphia similarly treate yields prismatic forms only. 492 NUX VOMICA AND STRYCHNIA. the alkaloid in a gallon (70,000) grains of water. Strychnia is very insoluble in water. It requires for its solution nearly 7000 times its weight of water at 50° (which is in the proportion of one grain in about fourteen measured ounces) and 2500 times its weight at 212°, But it is very soluble in alcohol, aether, benzole, and chloroform, and in some liquids in less common use. It is stated to be soluble in 350 parts of aether, 250 of benzole, 100 of alcohol, and 10 of chloroform. If pure it undergoes no change of colour when treated with the strong mineral acids ; but as it usually contains some brucia, it is reddened by nitric acid. Tests. — a.. The form of the crystals as above described. 6. The intensely bitter taste, c. The sparing solubility, d. The chemical colour tests, being the succession of rich hues imparted to a mixture of strychnia and strong sulphuric acid by contact with bichromate of potash and ferridcyanide of potassium and their solutions, or with the peroxide of lead and peroxide of manganese, e. The galvanic colour test, being the same coloui's developed by the electric current. The chemical and galvanic colour tests will now be separately described. The Colour Tests. — 1. Chemical colour tests, a. Place the smallest visible crystal or granule of strychnia on a surface of white porcelain, or on the glazed side of a piece of white enamelled glass. Add a drop of strong sulphuric acid, and mix the acid and alkaloid thoroughly with a small glass rod or spatula.* Kear this acid mixture, which is colourless, place a drop of a strong solution of bichromate of potash. Bring the two liquids together with the point of the rod or spatula, having previously placed the porcelain or glass in a favourable light. At the point of contact of the two liquids a deep rich blue colour will make its appearance, and extend wherever the two liquids mix. This colour soon changes to purple, from purple to crimson, and from crimson to a rich red brown. It then gradually fades into a bright red, which colour it retains for several hours, b. Proceed in the same manner with a weak solution of the ferridcyanide of potassium, which yields similar and highly characteristic results, c. Place a drop of strong sulphuric acid on a surface of porcelain or enamelled glass. Add a minute fragment of the peroxide of manganese (not more than will impart to the acid when mixed with it a neutral tint). Draw out a thin line of this acid liquid with the point of the rod or spatula, and bring it into contact with a minute fragment or crystal of strychnia. Similar colours will develop themselves wherever the alkaloid is brought into contact with the mixture, d. Proceed in the same way with the peroxide of lead, substituting for strong sulphuric acid a mix- ture of one part of nitric to thjree of sulphuric acid. The same colours will be developed. Of these tests, the first and last are to be preferred, though they all * The glass spatula consists of a long triangle or spear-head of thin glass, fixed by its short side in a wooden handle. It will le found very conveuient lor this and all similar purposes. POISONING BY STRYCHNIA. 493 give highly satisfactory results. It should be understood that they are equally applicable to spots of strychnia obtained by evaporating solutions of the alkaloid ; as also to its salts. 2. Galvanic Colour Test. — This, like the foregoing tests, is appli- cable either to a crystal or granule of strychnia, or to a deposit of the alkaloid from any of its solutions. It is thus described by Dr. Letheby: " Place a drop of a solution of strychnia (say of one part of the alkaloid in 10,000, or even 20,000 of water) into a cup- shaped depression made in a piece of platinum foil. Allow the liquid to evaporate, and, when dry, moisten the spot with a drop of concen- trated sulphuric acid. Connect the foil with the positive pole of a siugle cell of Grove's or Smee's battery, and then touch the acid with the platinum terminal of the negative pole. In an instant the violet colour will flash out, and on removing the pole from the acid the tint will remain." 2. Tn Solution. Strychnia differs from other poisons in the circumstance that the process now employed for extracting it from organic mixtures presents the poison not as an aqueous solution, but dissolved in one of the four liquids already specified, namely, alcohol, ajther, benzole, and chloro- form. The solution of strychnia in these reagents is allowed to evaporate in a watch-glass or on a disc of glass ; and if the liquid hold sufficient of the poison in solution, a number of deposits are obtained, which should first be examined by the microscope, and then submitted to the action of the various tests. One or more of the stains should be treated with dilute acetic acid, so as to convert the strychnia into the acetate. To this acetate of strychnia, more or less diluted, the several tests to be presently described are to be applied. Assuming this method of procedure to be adopted, the form of the deposits from the solutions of strychnia in the four liquids, alcohol, aither, benzole, and chloroform will be described, and then the effect of certain chemical tests on the solution indicated. Strychnia in alcohol, cether, benzole, and chloroform, a. In alcohol. The deposit from this solution is usually dendritic, but it may assume the shape of octahedra, long four-sided prisms and short six-sided prisms, with two long and four short sides. These forms are all depicted by Dr. Letheby (' Lancet,' June 28, 1856). 6. Tn cether. This crystalline deposit usually assumes similar forms, c. In benzole. The solution of stiychnia in benzole sometimes leaves on evaporation crystals of great brilliancy, distinctness, and permanence, in the form of octahedra, and of short six-sided prisms, the latter crystal consti- tuting the prevailing form. Cubes and dodecahedra are occasionally met with. Generally, however, the deposit, though crystalline, does not put on the form of distinct crystals, even when the stiychnia and benzole are apparently of great purity, d. In chloroform. The alkaloid is deposited from this solution in the forms of rosettes, veineil 494 NUX VOMICA AND STBTCHNIA. leaves, stellate dotted needles, circles with broken radii, and branched and leticulated forms of great delicacy aud beauty. Some of these Fig. 61. forms are shown in the annexed figure. My obsei-vation of these forms coincides with Dr. Letheby's as given in the paper just referred to. Other Chemical Tests. — A con- siderable number of chemical reagents have been recommended as tests for strychnia, among which the most im- portant are: — the solutions of iodine and iodide of potassium ; of the tannic and carbazotic acids ; of the chlorides of mercury (corrosive sublimate), pla- tinum, gold, and iron ; of the bichro- mate and perchlorate of potash ; and of the sulpho-cyanide of potassium. Some of these tests give amorphous precipitates, but the greater number throw down crystals, some of which are highly characteristic, aud sufficiently constant to be con- sidered as subsidiary tests. It may be well to premise that the acetate of strychnia itself, to a weak solution of which the tests are supposed to be applied, crystal- lizes in tufts of needles, as shown in 1, fig. 62, and that when exposed to the vapours of ammonia, it yields the crystals shown in figs. 59 and 60. Fig. 62. 1. 2. 3. a. Iodine and Iodide of Potassium (a solution of these reagents in the proportion of one grain of iodine and three grains of iodide of potassium in a drachm of distilled water) constitutes a valuable test for the alkaloids as a class, and for strychnia in particular. It produces in solutions containing strychnia an abundant yellowish or reddish- Itrown precipitate, partly amorphous, partly crystalline, b. Tannic acid. A solution of this acid yields an abundant white curdy pre- cipitate with the salts of strychnia, but it reacts similarly with other alkaloids, c. Carbazotic acid in solution yields with strychnia a white precipitate, aud stellate and radiating crystals, with notched and PHYSIOLOGICAL TEST. 495 hooked edges, as in 2. fig. 62. d. A solution of corrosive sublimate causes an abundant white precipitate, which assumes the highly cha- racteristic crystalline form depicted in 3, fig. 62. This is one of the best tests for strychnia, e. The bichloride of platinum yields a bright yellow precipitate. /. The terchloride of gold gives an abundant bright yellow precipitate which is dissolved by a few drops of liquor potassae. On boiling this solution, it assumes a deep purple tint, and rapidly deposits a precipitate of the same colour, g. The jjerchloride or permuriate of iron (causes an abundant yellow precipitate, and yellow octahedral crystals of great size and beauty, h. The bichromate of potash yields a bulky canary-yellow precipitate, consisting of abundant dendritic yellow crystals, with isolated colourless octahedra. i. The perchlorate of potash rapidly precipitates strychnia in long four-sided prisms, blended with other crystalline forms, k. The sul- phocyanide of potassium yields an abundant white precipitate. In making use of the foregoing tests it is necessary to bear in mind that some of them (as tests a and 6) give similar reactions with other alkaloids ; and that the crystalline foi-ms described or depicted are not uniform in their occurrence. Differences in temperature, in the strength of the solution of strychnia, and in the strength and purity of the reagents, give rise to modifications in the foi'ms of the crystals. Some of the reagents also (such as the bichloride of platinum) yield similar crystals of great distinctness and beauty. Hence, in all cases in which crystalline forms are examined under the microscope, a comparison should be made between the crystals resulting from the two liquids and those afforded by the reagent itself* The crystals depicted in fig. 62 are not obtained from any other alkaloid in the group of alka- loids to which strychnia belongs ; namely, that which is marked by the common property of not being changed in colour by strong sulphuric acid. The Physiological Test. — This title has been given to a test first pro- posed by the late Dr. Marshall Hall, who alleged that the common frog, properly prepared for experiment, was not less susceptible of the peculiar effects of strychnia than of the convulsive effects of galvanism. He directed that frogs recently taken from the pond should be selected ; that the skin should be well dried with blotting paper, and that the liquid to be tested, being a strong solution of a salt of strychnia, should * Refer to papers by Dr. Letheby in • Lancet,' June 28 and July 12, 1856. Also to two papers by Dr. Wormley in the ' Chemical Gazette,' April, I860. Dr. Letheby's papers present the microscopic forms of strychnia as obtained by means of several reagents, while those by Dr. Wormley give the results of carefully conducted experiments on the chemical reactions of strychnia ; from which it appears that the more important tests described above take rank in point of delicacy as follows:— The iodine test reacts with ^^^ grains of strychnia in a minim of water ; tannic acid with gjjWj ? bichloride of gold _i_ ; carbazotic acid ^ L^ ; bichromate of potash -r-^ ; bichloride of 496 NUX VOMICA AND STRYCHNIA. be dropped on the back of the animal. In a short time the frog thus treated became affected with tetanoid, or epileptoid spasm, or convul- sion, on the appliciition of the slightest cause of excitation. This test, according to Dr. Marshall Hall, detects so small a quantity as the jj^th gi-aiu of the poison ; and he thought that if inserted under the skin, or injected into the stomach, a still less quantity might be detected. The delicacy and certainty of this test have been fully confirmed by Dr. John Traill ('Lancet,' July 12th, 1856), by Di-. Harley, by Dr. Wormley, and others. Dr. Wormley (* Chemical News,' April 28th, 1860) gives an account of some experiments on a small species of frog (the Rana halecina), from which it appears that when a solution of strychnia was introduced into the stomach, quantities of strychnia much less than ^^th grain produced characteristic effects. The experiment is best performed as follows : Introduce the frog into a Powell's flat specimen glass, with the belly of the frog towards the flat surface ; close the opening with a cork perforated to allow the passage of a pipette and glass rod. The skin of the frog should be dried before it is introduced into the vessel. Apply a drop or two of a solution of one of the salts of strychnia, or a sQlution in alcohol of the alkaloid itself, by the point of the pipette to the skin of the back. In a period of time varying from one or two minutes to a quarter of an hour or more, the characteristic tetanic convulsions will show them- selves, and will recur every time the glass is shaken, or the frog touched with the glass rod. In many cases the frog utters a shriek or cry expressive of pain. When the dose is large, the symptoms show themselves almost immediately, and death takes place in a few minutes. When the dose is smaller, the symptoms come on after an interval of a quarter of an hour or half an hour, and the animal may recover. The characteristic symptom is generally ushered in by a state of evident distress, with panting respiration and protruding eye. 3. In Organic Substances. The process which seems best adapted to the detection of strychnia in the contents of the stomach, or in the animal fluids and tissues, is the one originally recommended by Stas, but since modified by the substitution of chloroform or benzole for aether.* The organic matters are first digested with from ten grains to half a drachm of tartaric acid, over a water-bath, till they are reduced to a fluid state. This liquid is then filtered, and the substance remaining on the filter washed with distilled water so long as it has an acid reaction, the washings being added to the filtrate. The liquid is then to be somewhat con- centrated by evaporation, and carbonate of soda is to be added in slight * Messrs. Rodgers and Glrdwood (' Medical Times and Gazette,' June 20th, 1857) treat the organic mixture with dilute hydrochloric acid (cue part acid and ten water), and ultimately resort to chloroform as a solvent of the alkaloid. EXPERIMENTS ON ANIMALS. 497 excess. The liquid is now to be strongly shaken for several minutes in a bottle or long tube with about half an ounce of chloroform (Messrs. Rodgers and Girdwood), or with benzole (Professor Bloxam). The chlo- roform, having been allowed to subside, or the benzole to collect on the surface, is drawn off by a pipette, transferred to an evaporating basin, and expelled over a water-bath. If the residue left in the basin is free from colour, it may be at once tested for strychnia ; but if not, it must be moistened with concentrated sulphuric acid, and exposed for some hours to the temperature of a water-bath, by which procedure all the organic matters except the strychnia is destroyed. The charred mass is then treated with water, and the solution filtered to separate the carbon. Ammonia is added to excess, and the solution again shaken with about a drachm of chloroform. If, on evaporating a small portion of this chloroform solution, and acting on the residue with strong sulphuric acid, any charring takes place, the same pro- cess must be repeated. The chloroform solution ultimately obtained affords strychnia sufficiently pure for the application of the several tests. The colour tests may be applied to the deposit left on a poi-ce- lain slab after repeated evaporations ; the deposit on a slip of glass may be examined under the microscope; and a solution of the de- posited matters in dilute acertic acid may be examined by the several tests just described. By this process very satisfactory results are obtained.* Strychnia has now been detected in the contents of the alimentary canal, in the muscles and viscera, and in the blood and urine. Messrs. Rodgers and Girdwood also state that they detected it in the bones. There is no longer any I'oom for doubt that strychnia, like arsenic, antimony, and mercury, undergoes no change in the alimentary canal, in the vessels of the body, or in the secreting organs ; but that it can be detected in organic fluids and tissues by a proper method of analysis carefully and skilfully conducted. In a medico-legal case lately examined by Professor Bloxam, he substituted benzole for chloroform, and obtained beautiful crystalline forais similar to those just mentioned as characterizing the deposit from a solution of strychnia in benzole. Benzole, though a less perfect solvent than chloroform, has the twofold advantage of being lighter than water, and leaving a crystalline deposit of a more marked character. Experiments on Animals. The effect of strychnia on animals varies with the dose of the poison, and the state in which it is administered. A large dose of a salt of strychnia given in solution may begin to act almost immediately, and prove fatal in a minute and a half. A smaller * See the particulars of a recent analysis by Dr. Letheby, in a case of poison- ing by strychnia, in the ' Chemical News,' September 29, 1860, and ' Br. Med. Journal,' August 4, 1860, in which a similar process was adopted. 2 K 498 NUX VOMICA AND STRYCHNIA. dose may not produce any effect for several minutes, and death may not ensue for twenty minutes or half an hour ; or severe symp- toms may be developed, and yet the animal recover. The symptoms produced by the poison in animals are well shown in the following instance. Dr. Taylor gave to a full-grown healthy rabbit, which had been recently fed, a quarter of a grain of sulphate of strychnia dissolved in a few drops of distilled water. The animal remained active for fifteen minutes, but at that time appeared easily startled, tremulous in its movements, and unsteady on its legs. Soon afterwards it trembled violently, or started when touched ; and slight twitchings occurred in the limbs at intervals on its attempting to move, or on making a noise. After the lapse of eighteen minutes no well-marked convulsion of the trunk had occurred ; but when gently lifted by the ears from the table to the- floor, it was seized with a violent convulsive paroxysm. The hind and fore legs were rigidly stretched out, and there was complete opisthotonos. Its eyes protruded ; its breathing was difficult ; the pulsa- tions of the heart could not be counted ; the head and tall were drawn backwards, as if by a tightened bow-string, with occasional slight intervals of relaxation ; and in this state it died, two minutes after the commencement of the convulsions, and twenty minutes after taking the poison. Immediately after death the whole body was flaccid ; but it speedily stiffened, and the fore limbs altered their position, and became rigidly stretched out. In eight minutes from the death, while the body was still warm, the muscles were rigid over the greater part of the trunk. On inspecting the body, the lungs were found collapsed, and of a bright red colour; the heart contained blood, chiefly coagu- lated, on both sides ; the blood in all other parts of the body was liquid, and dark coloured.* The mode and immediate cause of death in animals poisoned by strychnia are not uniform. From the experimental inquiries Instituted by Dr. Harley, of University College, London, and Mr. Bayldon, of Edinburgh, it may be inferred that death may take place by shock, by apncea, by syncope, or by exhaustion ; and that the poison affects no the nervous centres only, but the muscular tissue of the heart, and o: the voluntary muscles. SYMPTOMS, POST-MORTEM APPEARANCES, AND TREATMENT. Symptoms. — At an interval of from a few minutes to an hour oi more after swallowing a substance which, if in solution, would have i hot and intensely bitter taste, the symptoms of poisoning set in with i feeling of suffocation and difficulty of breathing, the patient complain' ing of want of air. These feelings of distress are soon followed by^ twitchings of the muscles, and jerking movements of the head and * For a minute account of several experiments on animals, and a collection of several cases in the human subject, with an examination of the case of Palmer, see Dr. Taylor's Essay, reprinted from the • Guy's Hospital Reports/ POISONING BY STRYCHNIA. TREATMENT. 499 limbs, which shortly become heightened into tetanic convulsions. The limbs are forcibly extended, the legs widely separated, and the feet often turned either inwards or outwards, the head bent back, and the whole body arched so as to rest on the head and heels. This position is technically designated ' opisthotonos.'' The muscles of the abdomen are rigidly contracted, respiration suspended, the face livid and con- gested, the pupil (in the fit) usually dilated, the eyes prominent and staring, and the features drawn into a grin (the risus sardonicus). The patient complains of a choking sensation, and of thirst and dryness of the throat ; but the effort to drink often occasions rigid and violent spasms of the muscles of the jaw. There is sometimes foaming at the mouth, and the froth is occasionally tinged with blood. The violent contractions of the muscles are accompanied by pain at the pit of the stomach and cramps in the limbs, and by intense suffering and distress. The pulse is very rapid. After the spasms have lasted for one or two minutes there is a remission of short duration, and the patient remains exhausted, and bathed in sweat. The fits sometimes i-eturn without apparent cause, but they may be brought on by the slightest touch, or the least effort of the patient. In the intervals of the fits the patient can converse, and swallow, and the jaw is not always fixed even in the fit. The mind is generally unaffected till towards the fatal termina- tion, and may even continue clear to the last. The patient is generally quite conscious of his danger, and aware of the approach of his paroxysms, which he announces by screams or shrieks, or by calling out that " they are coming ;" and he often asks to be held, moved, or turned over. Towards the fatal termination, the fits become more frequent and severe, and the patient dies exhausted, or suffocated, in most cases within two hours of the commencement of his symptoms. If a patient survive that period there would be fair hope, but not a certainty, of recovery. The post-mortem appearances in death by stiychnia are not highly characteristic, nor are they uniform. As a general rule, the body would seem to be relaxed at the time of death ; but it stiffens soon afterwards, and remains rigid for a long time. The hands are usually clenched, and the feet arched, or turned inwards. In some cases the body retains the posture given to it by the last fatal spasm. There is usually some lividity about the face, trunk, and limbs. The expression of the countenance is sometimes quite natural. The internal appear- ances consist in congestion of the brain and spinal cord, of the lungs and air-passages, and sometimes of the mucous membrane of the stomach. The heart is sometimes contracted, and all its cavities empty; in other cases the right side is full of blood. The blood throughout the body is black and fluid. The urinary bladder is empty. The treatment consists in the prompt evacuation of the stomach by emetics or the stomach-pump, and then in the administration of chloroform, for the relief of the pain attending the spasms. There is no antidote to the poison unless finely-divided charcoal is to be con- 500 NUX VOMICA AND STRYXilHNIA. sidered in that light. Opium, tobacco, and the active principles of tobacco and conium, have been recommended as tending to relieve the patient's sufferings, or relax the muscular contractions. Commencement of Symptoms. — The symptoms may show themselves in fi'om five minutes to an hour or more. Fatal Period. — Death may take place in fifteen minutes, or not till the lapse of two hours and three quarters. These were the limits in eleven cases which I have minutely analyzed. Fatal Dose. — A quarter of a grain of strychnia may destroy life ; but recovery may take place after much more considerable doses. From the account just given of the symptoms of poisoning by strychnia, it will be seen that they are closely allied to those of the dis- ease known as tetanus or locked jaw. In poisoning by strychnia, as in tetanus, there are violent paroxysms of rigid convulsion, with intense suffering ; and in both the mind is little if at all affected ; and when it does suffier, it is apparently as the result of the exquisite tor- tures which the patient has undergone. The differences between the disease, tetanus, and the effect of poison- ing by strychnia are well marked. In this country, and in temperate climates, tetanus is rare, except as the consequence of a wound or severe mechanical injury. In tetanus the symptoms are at first obscure, and develop themselves gradually: in poisoning by strychnia they are strongly marked at the onset, and attain their full development in a few minutes. Tetanus begins with difficulty of swallowing and stiff- ness of the jaws and neck, the trunk, legs, and arms being attacked in succession. In poisoning by strychnia, all, or nearly all, the voluntary muscles are attacked at the same time; and the muscles of the jaw are not only not affected first, but*sometimes wholly escape, or are violently contracted only during efforts to swallow. In tetanus, opisthotonos does not occur till after some hours or days : in poisoning by strychnia, it is among the early symptoms. In tetanus, the symptoms undergo abatement, but there is no perfect intermission: in poisoning by strychnia there are intervals of complete intermission. In tetanus the patient either dies after the lapse of several hours or days, or recovers slowly after several days or weeks : in poisoning by strychnia death happens in from less than a quarter of an hour to less than three hours after the first appearance of the symptoms, or the patient recovers in a f^vf hours. The tetanus occasioned by strychnia is distinguished from that which occurs in the coui'se of poisoning by several of the more active irritants and narcotico-irritants, inasmuch as the tetanus of strychnia-poisoning constitutes the one symptom, whereas the tetanus of irritant and nar- cotico-irritant poisoning occurs after other symptoms of poisoning have shown themselves, or is mixed up with them. To this rule, however, it is possible that the salts of morphia, in certain cases, may form an exception. (See p. 448 ) The tetanic convulsions of hysteric and epileptic seizures ar< BRUCIA. 501 similarly distinguished from the tetanus of strychnia-poisoning, by forming only a part of the fit. These seizures, moreover, are not in themselves fatal. Death from hysteria is unknown, and it very rarely follows immediately or speedily on an epileptic seizure. There is a marked difference, also, in the character of the convulsive movements in the diseases just specified, and in poisoning by strychnia. Strychnia produces a violent rigid tremor, uniformly continuous throughout the paroxysm ; whereas epileptic, epileptiform, or hysteric convulsions are marked by a more or less regular alternation of relaxation and contrac- tion of the muscles. In a word, the tetanic paroxysm is distinguished by uniform iHgid tremor, the epileptic or hysteric fit \>y jactitation. Brucia. This alkaloid derives its importance from its being associated with strychnia in the seed and bark of nux vomica, and in St. Ignatius' bean. It possesses the same poisonous properties as strychnia, but in a less degree of intensity, variously estimated at a sixth or a twelfth. Properties. — Brucia is usually found in the form of a white powder, consisting, in part, of crystals. It is more soluble in water than strychnia, insoluble in aether, but very soluble in alcohol. Its aqueous solution has an intensely bitter taste. With acids it forms salts. Strong and pure sulphuric acid does not discolour it ; but it is de- scribed as giving it at first contact a pale rose tint. Tests. — a. In common with many other alkaloids, brucia is precipi- tated of a red-brown colour by the solution of iodine in iodide of potas- sium, h. It is also precipitated white by tannic acid. c. Nitric acid imparts to brucia and its salts a deep rich red colour. This red solution, if wai-med and then allowed to cool, is changed to a purple hue by protochloride of tin, and bleached by an excess of the solution. d. Strong sulphuric acid, followed by bichromate of potash, ferrid- cyanide of potassium, and peroxide of lead, or peroxide of manganese, develops immediately a red or reddish-brown colour, passing to green and yellow, e. The ferridcyanide and sulphocyanide of potassium, the bichromate of potash, carbazotic acid, the bichloride of platinum, and the terchloi'ide of gold, also yield precipitates. (Consult a paper by Dr. Wormley in the * Chemical News,' July 21, 1860.) It will be seen from what has just been stated that brucia belongs to the same group of alkaloids as strychnia, namely, to the group which is characterized by the absence of colour when treated with strong sul- phuric acid. But it differs from strychnia in giving a more intense red with nitric acid, and in the absence of the rich deep blue tint developed by the contact of bichromate of potash in substance or solu- tion, with the solution of the alkaloid in sulphuric acid. The crystal- line forms yielded by strychnia with the several reagents ai'e also more distinct and characteristic than those afforded by brucia. 502 CHAPTER XIX. 1. Belladonna. 2. Hyoscyamus. 3. Stramonium. 4. Camphor. 5. (Enanthe crocata. 6. cocculus indicus. 7. Lolium temulentum. 8. Poisonous mushrooms. The poisons belonging to this group are characterized by the common leading property of causing delirium, with illusions of the senses. Other poisons of the narcotico-acrid class either do not give rise to delirium, or they produce it only exceptionally. They also share, with other poisons of the narcotico-acrid class, the property of causing dilata- tion of the pupil, but more constantly and in a more remarkable degree. Irritation of the stomach and bowels is present in a sufficient number of cases to justify their being classed with the narcotico-acrid poisons. Dysuria, or suppression of urine, is also not uncommon. The poisons at the head of the group are the most conspicuous of their class ; the others, as being less important, are more briefly noticed. For more ample details respecting them, reference must be made to treatises on toxicology. 1. Belladonna (Atropa Belladonna. Deadly Nightshade). This is a plant of the Linnsean class and order, Pentandi^ia Mono- gynia, and natural order, Solanacece. It is indigenous, and grows in waste shady spots. All parts of the plant are poisonous, and cases of poisoning by the root, leaves, and berries, and by the medicinal extract, are on record, several of which proved fatal. A decoction of the root, given as a clyster, has also caused death, and serious symptoms have followed the external appli- cation of the extract to a blistered surface. The plant owes its poisonous properties mainly to the alkaloid atropia, which has been admitted into the Pharmacopoeia, with one of its salts, the sulphate. The officinal preparations of the plant itself are, the extract, chiefly used externally, but occasionally internally, in doses of gr. ^ to gr. i, cautiously increased ; the tincture (dose from five to ten drops) ; and for external application, the emplastrum and unguentum belladonnas. BELLADONNA. 305 Fig. 63. ejected by the The parts of the plant which have been taken as poisons are readily recognized. The root is thick and fleshy, branched and creeping; its section, white when fresh, and greyish when dried. It has a slightly bitter taste. The leaves, often in pairs of unequal size, ovate and un- divided, smooth and soft, are attached to the stem by short foot-stalks. The berries of the size of a small cherry, furrowed on each side, of a shining violet black colour, and of a sweetish taste, are enclosed in the enlarged calices. They have two cells, which contain several seeds. The seeds are of the small size shown in fig. 63, with circular or oval outline, and rounded surfaces ; sometimes they are kidney-shaped. Their colour is nut-brown. They weigh about ninety to the grain. When viewed by a pocket lens, they look like sultana raisins in miniature, and are stndded closely with equal small round pro- jections. Viewed by leflected light, under a two-inch power of the microscope, they have the appearance shown in fig. 63. As all parts of the berries, and the seeds which they contain, are very indigestible, portions of them will be found, in cases of poisoning, in the matters stomach, or passed from the bowels. The entile plant has a lurid hue, and when bruised, a fetid odour. The extract of belladonna has the property which, however, it shares with that of hyoscyamus and stramonium, of causing dilatation of the pupil when locally applied, or when taken internally. The effects of belladonna on animals are not very characteristic. In them, as in man, it dilates the pupils, and it produces a state allied to intoxication. In the human subject, the symptoms of poisoning by belladonna are the following : dryness of the throat, great difficulty of swallowing, or even total inability to swallow, and intense thirst, followed by delirium, ending in coma, or alternating with it. Convulsions are rare, and when present, generally slight. The pupil is largely dilated, the coun- tenance flashed and swollen, the eyes prominent and sparkling, the vision indistinct, the gait unsteady. Symptoms of irritation in the alimentary canal, beyond dryness and constriction of the throat, are of very rare occurrence ; but nausea and unsuccessful efforts to vomit are recorded in some cases, and aphthous inflammation of the throat, swell- ing of the abdomen, and discharge of blood by stool, in at least one instance. Violent strangury, suppression of urine, and hajmaturia, have also been reported, as also an eruption on the skin, said to resemble that of scarlatina. The symptoms rarely show themselves till two or three hours, or even more, after the swallowing of the poison ; but in some instances they have set in within half an hour. The fatal cases bear but a small proportion to the cases of recovery. Death, when it occurs, takes place within twenty-four hours ; in one case in fifteen hours : in another in twelve hours. Favourable cases often last 504 ATROPIA. for two or three days or more ; and some of the leading symptoms, such as impaired vision, and greatly dilated pupil, survive the recovery of the patient. The delirium is generally a very prominent symptom. It is some- times pleasing, sometimes accompanied by uncontrollable laughter, sometimes by incessant talking, sometimes only by motions of the lips, the voice being lost. Sometimes the state of the patient closely re- sembles somnambulism, at others intoxication. The patient is generally unconscious, and, on recovery, does not recollect what has happened to him. Generally, the delirium precedes the sopor or coma; but some- times the order is reversed, and sometimes the two states alternate. Trismus and subsultus tendinum are i-ecorded among the nervous symptoms of occasional occurience. The vision is affected synchronously with the extreme dilatation of the pupil. Sometimes there is merely indistinctness of vision, some- times double vision, sometimes utter insensibility of the retina. The post-mortem appearances are sometimes quite unimportant; in other instances they have been described as those of narcotico-irritant poisoning. The vessels of the brain are congested, and there are patches of redness in the pharynx and oesophagus, and at the cardiac end of the stomach. The mucous membrane of the stomach has been found dyed of a dark purple colour throughout, or in patches, and portions of the berries and some of the seeds have been detected in the intestinal canal. The treatment consists in the prompt administration of emetics, fol- lowed by animal charcoal diffused through water, and this, after an interval, by a full dose of castor oil. In other respects it will be deter- mined by the symptoms actually present. Bleeding may be practised with advantage. The diagnosis of the poisoning is not free from difficulty. The symptoms are very similar to those present in poisoning by hyoscyamus and stramonium. It is only the discovery of some portion of the plant itself in the substances rejected from the stomach, or passed from the bowels; or, in a fatal event, in the contents of the ahmentary canal, which will enable us to state with confidence what poison has been taken. In many instances the description given of the part of the plant swallowed is quite decisive. The berry is easy to recognize. Atropia (^Atropine). — This alkaloid, with one of its salts (the sul- phate), is admitted into the London Pharmacopoeia, and used medicinally. Properties. — When pure, it is in the form of white silky crystals, which when viewed under the microscope are four-sided prisms. It is sparingly soluble in water, but soluble in alcohol and a;ther. It is also soluble in the dilute acids, with which it forms crystallizable salts. The solution of iodine in iodide of potassium, and tannic acid, throw down respectively a greenish-brown and dirty white precipitate. Tests. — It is dissolved by sulphuric acid, and the solution is changed to a rich brown when heated. This solution also bleaches a solution of the permanganate of potash ; and with a solution of the bichromate HYOSCYAMUS. 505 of potash yields a rich red colour, changing to red-brown and yellow. Nitric acid dissolves it without change of colour. The bichloride of pla- tinum and the terchloride of gold yield yellow precipitates. The solu- tion of the alltaloid, and of its salts, has the property, which, however, it shares with hyoscyamia and daturia, of causing dilatation of the pupil. The alkaloid may be detected in organic mixtures, when it is in sufficient quantity, by the method of Stas — a method which, as it is applicable to the isolation and identification of the alkaloids as a class, may be here conveniently described. This method is founded on the ascertained fact that the salts of the alkaloids are soluble in water and in alcohol ; and that their aqueous and alcoholic solutions, when neu- tralized by an alkali, so as to set free the base, and then shaken with aether, yield the base to the aether. The folio v/ing are the several leading steps of this process. The organic matters cut into small fragments are first mixed with double their weight of strong pure alcohol ; from 8 to 30 grains of tartaric or oxalic acid are added, and the mixture heated over a water- bath. When cold the liquid is filtered, and the matters on the filter are washed with strong alcohol, and the washings added to the filtrate, which is then evaporated in vacuo over sulphuric acid. The residue is now treated with cold anhydrous alcohol, the alcoholic extract evaporated to dryness, and this residue in its turn dissolved in a very small quantity of distilled water. This aqueous solution is mixed with powdered bicarbonate of soda or potash till effervescence ceases, and then shaken up with from four to six times its volume of pure rectified aether. When the aether has collected on the surface, it is with- drawn by the pipette, and evaporated in a watch-glass. The deposit contains the alkaloid. Some parts of this process are repeated in order to insure greater purity in the ultimate result. (For a more detailed account of this process, and the modifications required in the case of the volatile alkaloids, see Otto's * Manual of the Detection of Poisons,' p. 156.) 2. Hyoscvamus (Byoscyamus Niger. Henbane). This, too, is a plant of the Linnaean class and order Pentandria Monogynia,and of the natural order Solanacese. It is indigenous, and grows on waste and poor lands, and on the sea -shore. All parts of the plant are poisonous, and the seeds, root, leaves, and young shoots have severally been taken as poisons. The plant owes its poisonous property to an alkaloid known as hyoscyamia, and a peculiar volatile pi'inciple. The London Pharmacopoeia contains two preparations of henbane — the extract, procured from the fiesh leaves, and the tincture, from the dried leaves. The dose of the extract is from 5 grains to a scruple, and of the tincture from 20 drops to a drachm, a drachm and a half, 01' two drachms. These preparations are of very variable strength. 506 HY08CYAMUS. The several parts of the plant which have been taken as poisons are easily recognized. The seeds are of about the same size and shape as those of bella- donna, but less rounded. They are about an eighteenth of an inch in Fig. 64. diameter, and weigh 120 to the grain. Under the pocket lens they appear dotted over their entire surface by slight projections ; and under the lower powers of the microscope they look very much like pine-apples in miniature, being thickly covered with ridges formed of nipple-like projections separated by distinct furrows, the projections being marked with black lines, as shown in fig. 64, which represents the seeds of their usual size, and as seen by reflected light under a two-inch power of the microscope. The root is spindle-shaped, and bears some resemblance to a small parsnep, for which it has been eaten by mistake. It also somewhat resembles the wild chicory. The leaves are of a pale dull green colour, slightly pubescent, with long hairs upon the midrib, unequally cut at the sides and pointed at the end. They are sessile, and half embrace the stem of the plant. They have, in common with the rest of the plant, a strong and un- pleasant odour, a mucilaginous and slightly acrid taste, and a clammv feel. The different parts of the plant, and its officinal preparations, vary greatly in activity and strength, according to the season of the year and the mode of preparation. Effects of the Poison on Animals. — Purely narcotic ; no local symp- toms. Dilatation of the pupils a very marked symptom. Symptoms in Man. — The symptoms make their appearance in from a few minutes to half an hour. When fully developed, they consist of flushing of the face, giddiness, rapid pulse, weakness, and trembling of the limbs, convulsive or tetanic movements, delirium (commonly of the active or violent kind), incoherence, the delirium tentiinating in coma, or alternating with it, loss of speech, great dilatation of the pupil, and indistinctness of vision, or total loss of sight. Heat and dryness of the throat, vomiting and diarrhoea, are present in a sufficient number of cases to justify us in placing henbane among the narcoti co-acrid poisons ; but those symptoms certainly occur in a minority of cases. A cutaneous rash has been observed. Poisonous effects have been produced by a poultice of the leaves applied to the abdomen, and by a decoction of" the plant used as a clyster. The most characteristic symptoms are delirium, and dilated pupil. This dilatation of the pupil is caused by the application to the eye of the preparations of henbane. The post-mortem appearances are congestion of the brain and lungs. The treatment is that of poisoning by belladonna. STRAMONIUM. 507 In consequence of this poison being generally taken by mistake for some wholesome vegetable (either leaves or root), and cooked as an article of diet, the symptoms have commonly been described as affecting several persons simultaneously. HvoscvAMiA {Hyoscyamine). — This rare alkaloid is sometimes seen in the form of white silky crystals, but generally as an amorphous mass. It is without odour when quite pure ; but, as generally procured, has a very disagreeable odour, like that of tobacco, and an acrid taste. It is not very soluble in water, but more readily dissolved in alcohol and aether. It forms salts with acids. Strong nitric acid dissolves it with- out change of colour, and strong sulphuric acid colours it brown. It is one of the alkaloids which M. Stas succeeded in obtaining by his process, for a description of which see p. 505. 3. Stramonium (Datura Stramonium, Thorn-Apple). This also is a plant of the Linnaan class and order Pentandria Mono- gynia, and natural order Solanaceee ; growing in waste places and on dung-heaps in all parts of Europe. Every part of the plant is poisonous ; but the fruit and seeds are believed to be the most active. The vapour of the flowers is asserted to have produced poisonous effects. In France and Germany, as also in India, and the Eastern Archipelago, the seeds are administered intentionally to facilitate the commission of crime. Cases of poisoning by the leaves, fruit, seeds, and extract are on record. Dangerous symptoms have been occasioned by the external application of the several parts of the plant. The extract of stramonium is in the London Pharmacopoeia, and is given in doses of J gr. to 2 or 3 grains, or it may be applied ex- ternally. It is smoked with tobacco as a remedy for asthma. Stramonium owes its poisonous properties to an alkaloid, known as daturia. The appearance of the plant and of its parts is highly characteristic. The entire plant has a rank odour. The flowers, however, are sweet- scented. The leaves are of a dull green colour : they are large, sharply and irregularly cut at the edges, smooth, ribbed, and veined. ThQ fruity or apple, is as large as a walnut, and has a strong prickly outer coat. The seeds are light brown or black, circular or nearly so, sometimes kiduey-shaped, flattened, with a corrugated surface. They are much larger than the seeds of henbane or belladonna, which they resemble in shape ; for while the seeds of henbane measure about the eighteenth 6f an inch, and the seeds of belladonna about the sixteenth, the stramo- nium seed measures about the eighth of an inch, or from that to the tenth of an inch; and while the seeds of henbane weigh 120 to the grain, and those of belladonna 90 to the grain, there are only about 8 508 CAMPHOR. stramonium seeds in one grain. The size and the microscopic appeal ance of the cuticle of the seeds are shown in the annexed figui*e. Fig. 65. fit* • • The effects of this poison on animals are not very characteristic. In common with henbane and deadly nightshade it causes extreme dilata- tion of the pupil. The symptoms of poisoning by stramonium, in the huma,n subject, nearly resemble those of poisoning by henbane and the deadly night- shade. There are dryness of the throat, flushing of the face, dilatation of the pupils, delirium, accompanied by convulsions and followed by coma, and, in some instances, symptoms of irritation in the alimen- tary canal. The symptoms set in very soon after taking the poison, and seem to be more severe than those of poisoning either by henbane or deadly nightshade. Delirium may be present in as short a space of time as 15 minutes, and death may take place in 7 hours. Post-mx)rtem Appearances. — In some cases congestion of the vessels of the brain has existed, and in one instance redness of the cardiac end of the stomach. The treatment of cases of poisoning by stramonium will consist in the prompt use of emetics, followed by full doses of castor oil ; and where there is much flushing of the face, the abstraction of blood from the arm, or by leeches to the temple. In one case reported in * Rust's Magazine,* bleeding appears to have afforded great relief, and would seem to be applicable in poisoning by henbane and deadly night- shade, as well as the thorn apple, and in cases of poisoning generally where the face is flushed and the eyes prominent and brilliant. Daturia. — This alkaloid is believed to differ very little in its com- position and properties from atropia : like it, it is found in silky crystals, which are four-sided prisms. It produces the same effect on the pupil of the eye as the alkaloids atropia and hyoscyamia. The diagnosis of poisoning by stramonium is only possible by the history of the case, or by the discovery of portions of the plant in the alimentary canal, or in the matters vomited or purged. 4. Camphor. This substance has decidedly poisonous properties, but has only proved fatal in one instance. Properties. — It is a colourless, translucent, and semi-crystalline (ENANTHE CROC ATA. 509 substance of a tough texture, strong and peculiar odour, and pungent and yet cool taste. It floats on water, in which it is sparingly soluble. It evaporates at common temperatures, and is deposited on cool sur- faces (as on the inside of bottles) in crystals. It is readily dissolved by alcohol, aether, and chloroform, and by the volatile and fixed oils. When swallowed it impacts its peculiar odour to the breath. When taken as a poison it is usually in fragments, and being sparingly soluble in the contents of the stomach, would be easily identified in a fatal case. If dissolved in spirits, it may be separated by distillation, and then thrown down by the addition of water. The symptoms of poisoning by camphor begin with languor, giddi- ness, dimness of vision, and confusion of intellect, which are followed by feelings of depression, intoxication, or violent delirium. Convul- sions also occur, especially in children ; and there js much excitement of the circulation, with heat of skin, flushed face, and hurried pulse ; and the pupils are dilated. The post-mortem appearances, as observed in animals, are distinct marks of inflammation in the stomach and bowels, injection of the membranes of the brain, and an inflammatory condition of the urinary passages. Every part of the bodies of the animals had the odour of the poison. The smallest fatal dose has not been ascertained. Two scruples have produced serious symptoms in an adult male. The treatment consists in the prompt use of emetics, followed by castor oil as a purgative. The discharge of the contents of the stomach is generally followed by speedy relief. 5. ffiNANTHE CROCATA [Hemlock Water Dropwort). This is an indigenous umbelliferous plant, which grows on the banks of streams and ditches, and bears some resemblance to celery. All parts of the plant are poisonous ; but the root, from a rough resem- blance to the parsnep, is generally the part eaten by mistake. The plant is so virulent a poison that a very small piece of the root has proved rapidly fatal. The symptoms may set in as soon as twenty minutes after swallow- ing the poison, with convulsions and insensibility. The face livid and bloated, the mouth and nostrils covered with bloody foam, and the respiration stertorous, and death may follow in as little as five minutes from the first seizure. In more protracted cases nervous symptoms of great severity show themselves, consisting of locked jaw, tetanic spasms, and violent mania, or delirium allied to delirium tremens. The pupil is usually dilated. There are also symptoms of violent irritation in the alimentary canal. The post-mortem appearances consist of great congestion of the brain ; an accumulation of dark blood in the lungs, heart, and larp-^ vessels; and signs of irritation in the stomach and bowels. 510 POISONOUS MUSHROOMS. The treatment consists in the prompt discharge of the contents of the stomach by emetics, followed by a full dose of castor oil. Bleeding is indicated by the congested state of the cerebral vessels. The remainder of the treatment will be determined by the symptoms actually present. 6. COCCULUS INDICUS {Levant Nut). This is the berry of a plant known as the Menispermum, or Ana- mirta Cocculus. It is of the size and shape, and exhibits the section Pj gg^ shown in fig. 66. The shell acts as an emetic, while the seed itself contains an active poison (Picrotoxia), in the propor- tion of from 1 to 2 per cent. An extract of the berries is sold for poisoning fish, to which, when used in large quantity, it im- parts a poisonous property, and a decoction or extract is employed to give an intoxi- cating quality to ale, porter, and spirits. It is used, too, with this intent by thieves. In two instances, at least, the poison has proved fatal in the human subject. The symptoms are those of severe irritation in the alimentary canal, and cerebral effects, including delirium, and •* a lethargic stupor, with a consciousness of passing events, but a complete loss of voluntary power." (Taylor.) Picrotoxia {Picrotoxine). — This poison is obtained in the form of colourless crystals, which are long four-sided prisms. Its taste is intensely bitter. The crystals are sparingly soluble in water, but are readily "dissolved by alcohol and fether. It is also sparingly soluble in acids, but soluble in solutions of potash and soda. For this reason, and because it does not contain nitrogen, it is not properly grouped with the alkaloids. (Otto.) Sulphuric acid dissolves it without change of colour, but the acid solution becomes yellowish when it is warmed, and brown when it is heated. On the addition of a solution of bichro- mate of potash to the acid liquid, it assumes a rich yellow tint. Nitric acid dissolves it without change of colour. An alkaline solution, with addition of sulphate of copper, when heated deposits the oxide of copper. 7. LOLIUM TEMULENTUM {Darnel). The seeds of this plant are sometimes mixed with other grains, used for distillation, or ground into flour for making bread. When so used they may produce marked symptoms of narcotico-acrid poi- soning, including headache, giddiness, staggering as if from intoxica- tion, strong tremulous movements of the limbs, impaired vision, symptoms of collapse, and vomiting. 8. Poisonous Mushrooms or Fungi, The fungi constitute a large class of plants, of which some are habi- POISONOUS MUSHROOMS. 511 tually eaten with impunity, except by a few persons of peculiar consti- tution ; while the majority, especially those belonging to the three genera Amanita, Agaricus, and Hypophyllum are poisonous. The poisonous property is sometimes destroyed by heat ; but in other cases, when it is due to an alkaloidal principle known as fungia or fungine, it is permanent. The symptoms of poisoning by this class of substances are very variable in the time at which they appear, sometimes coming on soon after eating them, in other cases not till the lapse of perhaps twenty- four or even thirty-six hours. Cases also ditler fi-om each other in the order in which the symptoms are developed. Sometimes symptoms of irritation of the alimentary canal precede the nervous symptoms, but sometimes they follow them ; and in the same group of cases, some patients will sufler from symptoms of irritation, others from nervous symptoms. The symptoms of irritation consist of vomiting, with or without purging; and the nervous symptoms of headache, giddiness, dimness or confusion of sight, intoxication, delirium, or coma. The post-mortem appearances consist in marks of inflammation in the stomach and bowels, and of congestion in the brain. The treatment consists in the prompt use of emetics, followed by a full dose of castor oil. Precautions. — As a general rule, highly-coloured mushrooms and fungi, and those which grow in damp and shady spots, as well as those which have a disagreeable odour, and astringent taste, are to be re- jected as articles of food. The orange-coloured amanita muscaria, which appears in the autumn, is one of the most poisonous species, and should especially be avoided. ;i2 CHAPTER XX. 1. Aconite. 2. Digitalis. 3. Tobacco. 4. Lobelia inflata. 5. CONIUM. The poisons contained in this chapter are characterized by the effect they produce on the organs of circulation and respiration ; their lead- ing symptom being syncope or asphyxia, while the mental faculties are generally, but not universally, unaffected. The irritation of the ali- mentary canal which characterizes the whole class of narcotico-acrids is, as a general rule, more strongly marked in the case of these poisons than of those contained in the preceding chapter. 1, Aconite (^Aconitum Napellus, Monkshood, Wolfsbane, Blue-rocket). With the exception of the Aconitum ferox, which grows on the Himalayan mountains in India, the Aconitum napellus is the most active poisonous plant of the many which go by the name of aconite. Some of them have no poisonous property whatever. But not only is the Aconitum napellus, with this single exception, the most active poi- sonous plant bearing the name of aconite ; it is also, when compared with other poisonous plants, a very fatal one ; and there is reason to believe that aconitina, the active principle of the plant, is the most deadly poison in existence. Monkshood is a beautiful plant, growing from two to six feet in height, with dark-green leaves, of very characteristic form, and a ter- minal spike of rich blue flowers. It grows on hilly ground in many parts of Europe, is supposed to be indigenous, and is often cultivated as a garden flower. It belongs to the Linnajan class and order, Foly- andria trigynia, and the natural order Ranunculacece, or crowfoots. All parts of the plant are poisonous, but the root is the most active. Both the root and the haves have been several times taken as poisons ; and liie extract and tincture have also proved fatal. The London Pharmacopoeia contains two preparations of monkshood ; an extract from the bruised leaves, and a tincture from the coarsely powdered root. The dose of the extract is from one to two gi'ains, and that of the tincture from three to five drops. ACONITE. 513 The leaves, seeds, and root of the Aconitum uapellus are identified. The leaves are completely divided to the base into five wedge-shaped lobes, which are again divided into three, the segments being linear. They are not liable to be mistaken for the leaves of any other plant. The seeds are numerous, three-sided, iiregularly twisted, and wrinkled, of a black or dark -brown colour, about a sixth of an inch long, and weighing 25 to the grain. Fig. 67 shows their size and shape, and fig. 68 the markings on their surface, as seen under the Fig. -67. Fig. 68. microscope. A single seed contains enough of the active principle of the plant to produce numbness and tingling of the lips, tongue, and throat. The root requires to be more minutely described, since it has, on more than one occasion, been scraped and eaten instead of the horse-radish. This accident occurred in 1836 to a Mr. and Mrs. Prescott and their child, whose cases are minutely described by Dj-. Pereira ; in 1842 to a lady residing at Lambeth (Taylor); so lately as the winter of 1853 to two brothers, of whom one died and the other recovered. Still more recently, in the winter ot 1856, the poison proved fatal to two priests at Dingwall, and to a third person out of five who were affected at a dinner there. In the next year, 1857, a case occurred in London. Besides these accidental cases, the root has been given intentionally in one instance at least. It is not easy to understand how the root of monkshood should have been mistaken for that of the horse-radish, even though the respective plants were not attached to the roots to render the mis- take impossible ; and though the section of both roots is white when fresh, the scrapings of the two roots are distinguishable, the monkshood being friable and succulent, the horse-radish tough ahd stringy, and the first soon acquire a pink colour while the second retain their whiteness. The monkshood-root differs from that of the horse-radish in shape, in colour, and in taste. The root of monkshood is conical, and throws off a large number of curling fibres, and it is not tmusual to find one or more pear-shaped tubers, attached by naiTOW necks to the upper part of the root-stock, as in the specimens shown in the three figures annexed, which, with the single root in fig. 70, were selected out of a large number of freshly-dug roots of Aconitum uapellus, as pre- 2l EXPERIMENTS ON ANIMALS. 515 sentiDg the most characteristic varieties of form. The figures are of the size of the roots themselves. On the other hand, the root, or, as it is commonly called, the stick of the horse-radish (fig. 71) is cylindrical in all its larger branches, and throws off straight rootlets. The colour of the monkshood-root is a dark nut-brown externally, that of the horse-radish is buff-coloured. The root of the monkshood when chewed causes a peculiar tingling and numbing sensation in the lips, with a feeling of enlargement, and a similar sensation in the throat, when swallowed ; and this sensation in the lips and throat con- tinues for several hours : the taste of the horse-radish is pungent and sweet ; causing profuse lacrymation, but not being very persistent. This peculiar property which the root of the monkshood possesses, of causing numbness and tingling of the lips, is shared by the other parts of the plant, such as the leaves and seeds. Experiments on Animals. — Experiments on animals have been made with monkshood, and its active principle aconitina, by Sir B. Brodie, Orfila, Christison, and Pereira, and more recently by Drs. Fleming and Headland. According to Dr. Fleming, aconite, when introduced into the system of one of the lower animals, causes, successively, weakness of the limbs and staggering; accelerated, or slow and labouring respiration ; paralysis ; diminution or total loss of sensibility of the surface ; dim- ness of vision, or actual blindness ; increasing difficulty of breathing ; and, after a few spasmodic twitches, death by asphyxia. On examining the body immediately after death, the heart is found beating with con- siderable strength, which it continues to do for some time ; the peristaltic action of the intestines also continues ; the irritability of the voluntary muscles is impaired but not extinguished; there is general venous con- gestion, with distension of the right side of the heart and large veins, and venous blood is usually found in. the left cavities of the heart, and in the aorta. The venous system of the brain is often gorged with blood. Dr. Fleming adds that in some of his experiments there were decided convulsive movements, and, in two instances, distinct opistho- tonos ; that in general the pupil was more or less contracted ;* that the pulse became weaker and less frequent ; and that the poison did not appear to give rise to any local imtation. From other experiments of Dr. Fleming's it would appear that aconite* proves poisonous to vegetables. From Dr. Fleming's experiments, then, it would seem that aconite occasions muscular debility or actual paralysis, extending from the muscles of the extremities to those of the chest ; that it acts as a sedative to the heart; that it impairs or destroys common sensibility ; and that it proves fatal by inducing asphyxia. Asphyxia, however, is not the only mode of death in poisoning by inonkshood ; for Dr. Fleming dis- tinctly recognizes three possible modes of death. 1. It may prove * This statement is opposed to Dr. Headland's experience. He found that it caused in animals dilatation of the pupil, but in a less degree than belladonna. ('Lancet,' March 29, 1856.) 51G ACONITE. fatiil by a powerfully sedative impression on the nervous system, death tiiking place in a few seconds ; 2. It may prove fatal by suspension of the respiratory function ; and 3. It may prove fatal by syncope. Shock, asphyxia, and syncope, then, are the three modes of death in animals poisoned by aconite. In the human subject, accoi'ding to Dr. Fleming, syncope is the common cause of death. The symptoms of poisoning by monkshood in the human subject are : — numbness, tingling, and burning heat in the mouth, throat, and stomach, followed by nausea and vomiting, with pain and tenderness of the epigastrium. The numbness and tingling speedily become general, with diminished sensibility of the surface, vertigo, dimness of vision, or complete blindness, tinnitus aurium, and occasionally deaf- ness ; frothing at the mouth ; sense of constriction in the throat, with sensations of weight and enlargement of various parts of the body, but especially of the face and ears ; great muscular feebleness, with genei'al trembling ; more or less difficulty of breathing, and speechless- ness ; a distressing sense of sinking at the pit of the stomach, and dread of approaching death. The pulse becomes small, feeble, irregular, and finally imperceptible both at the wrist and heart ; the extremities, and afterwards the whole body, become cold, and a clammy sweat bedews the surface ; finally, the countenance grows blanched, the lips bloodless, and with a few hurried gasps the individual expires. He usually retains perfect possession of his mental faculties till the last, and exhibits no tendency to sleep ; or there may be slight wandering delirium. The fatal result is often sudden. Fost-mortem Appearances. — These are general venous congestion, and, in some cases, engorgement of the brain and its membranes, with considerable sub-arachnoid effusion ; also occasionally signs of gastro- intestinal irritation. Commencement of Symptoms. — The symptoms of poisoning may commence in a few minutes, or not for one or two hours. Fatal Feriod. — The preparations of aconite may destroy life in as little as an hour and a quarter. The extreme limit of survivorship appears to be twenty hours. The average is less than four hours, and the majority of deaths occur within three hours. Fatal Dose. — Of ihe root, it is believed that less than a drachm has proved fatal ; of the alcoholic extract, four grains ; of the tincture, a drachm. But very severe symptoms have been produced by much smaller quantities. Dr. Headland thinks that so little as a tenth of a grain of the alkaloid aconitina would destroy an adult male ; and Dr. Herapath performed an analysis in a case at Bristol, from which he inferred that ^'^th of a grain had proved fatal. Treatment. — There is no antidote to this poison, unless animal char- coal, recom.raended by Dr. Headland, is to be considered in that light. The treatment will therefore consist in the prompt administration of an emetic, followed, after an interval of time, by a full dose of castor-oil. The remote effects of the poison must be met by stimulants, such as DIGITALIS. 517 hot brandy and water, and ammonia. Strong coffee may also be given with advantage. Dr. Fleming also recommends friction along the course of the spine, and on the extremities, with warm cloths and spi- rituous liniments, and sinapisms, or bottles of hot water to the prsecordia and extremities. Convulsions, should they come on, are to be treated by opening the jugular vein ; and great dyspnoea, and extreme feeble- ness of the heart's action, by artificial respiration, and slight galvanic shocks passed through the heart. Diagnosis. — In some instances we are able to identify some portions of the plant itself in the contents of the alimentary canal. An alcoholic extract of the contents of the stomach may be tested by the taste. The numbness and tingling of the lips would serve to prove the pre- sence of aconite. Dr. Headland suggests that we should administer to some of the smaller animals an alcoholic extract of the contents of the stomach previously reduced by evaporation. ACONITINA (aconitine).— This alkaloid is so active a poison that, according to Dr. Headland's experiments, 3^ grain will kill a mouse; •j^, a small bird in a few minutes, and 3L almost instantaneously; g'o of a grain a cat, and j'g of a grain the same animal in twenty minutes or half^ an hour. Dr. Headland is of opinion that jL of a grain would prove fatal to an adult man. This estimate appears to be borne out by Dr. Herapath's case, y;^ grain causes tingling and numbness of the tip of the tongue, and -^ of a grain dissolved in spirit, and rubbed into the skin, causes loss of feeling, lasting for some time. Aconitina may be separated from organic liquids by the method of Stas (p. 505), or by a similar method suggested by Dr. Headland. In the fresh root, the alkaloid is contained in the proportion of a quarter to three quarters of a grain in the ounce, and in the dried root, of twelve to thirty-six grains to the pound. Properties. — Aconitina may be obtained in a crystalline form, but generally it is seen as a white powder. It is sparingly soluble in water, but soluble in alcohol and ather, and in acids. Its salts are not crys- talline. It has an acrid taste, and strong alkaline reaction. It resembles the other alkaloids in melting and depositing carbon when heated by the spirit-lamp, and in being precipitated by the solution of iodine in iodide of potassium, and by tannin. Tests. — a. Strong sulphuric acid dissolves it without change of colour, but when heated, it assumes a deep brown tint. b. A solution of bichromate of potash added to the acid solution colours it yellow, c. A solution of the peimanganate of potash added to the same solu- tion is bleached, d. Nitric acid dissolves it, without change of colour. e. The terchloride of gold gives a yellowish-white precipitate. /. The bichloride of platinum yields no precipitate. 2. Digitalis {Digitalis purpurea — 'Foxglove, purple foxglove). This is an indigenous plant, commonly met with about banks and hedge-rows, and in pastures, on a gravelly or sandy soil. It is also 518 DIGITALIS. cultivated in gardens, and is easily recognized by its purple dotted Howers. It beloncrs to the Linnaean class and order Didynamia angiospermta, and natural order Scrophiilariaccx, or figwoits. All the parts of the plant are believed to be poisonous, and the leaves have more than once destroyed life. The plant owes its poisonous property to the alkaloid digifalia, which exists in the fresh leaves in the proportion of less than one per cent. The leaves of the foxglove are officinal in the London PharmacopoBia. The dried leaves powdered are given in doses of from one to three grains ; an infusion made from the dried leaves is-given in doses of from |ss. to ^i. ; and a tincture, also prepared from the dried leaves, in doses . of from ten drops to half a drachm, cautiously increased. The root of the foxglove consists of numerous long and slender fibres, and is not, therefore, likely to be confounded with any of the common edible roots. The leaves are ovate, narrowed at the base, crenate, rugous, and veined, downy, especially on the under surface. The dried leaves have a dull green colour, a faint odour, and a bitter, nauseous taste. The seeds are of the small size shown in fig. 72, and weigh about 1,126 to a grain. They are of a light browii ^' colour, cylindrical, ovoid or conical in shape, and when viewed by the lens or microscope, present the pitted appearance shown in the figure. They may be mistaken for the seeds of the Lobelia iniflata, ^^f§^^^^ which they resemble in colour and size. They are, ^Mp^B^^y however, larger. BBr -* «^pF Experiine7its on Animals. — In moderate doses ^ZL—1JL1^^ digitalis causes vomiting, giddiness, languor, and death in twenty-four hours. In larger doses, in addition to these symptoms, tremors, convulsions, stupor, and coma. Injected into the veins, it destroys life in a few seconds, by acting on the heart and on the pulmonary circulation. In one of Mr. Blake's experiments, an infusion of three di-achms of the leaves injected into the jugular vein arrested the action of the heart in five seconds, that organ after death being motionless, turgid, inirritable, and its left cavities full of fiorid blood. Symptoms. — In the human subject, a single fatal dose of the poison produces the following symptoms: — Vomiting, purging, and severe colicky pains in the abdomen ; pain in the head, giddiness, and dim- ness of vision, or actual blindness; a dilated and insensible pupil; a slow, weak, and irregular, or intermittent pnlse ; nausea and faintness, with occasional syncope ; the skin is covered with a cold perspiration ; the patient is much worse when he assumes the upright posture. Sali- vation is a common occurrence. The urine is suppressed ; convulsions occasionally occur ; and the patient sometimes continues for a consider- able space of time in a state of stupor. In two fatal cases death took EXPERIMENTS ON ANIMALS. 519 place in twenty-two hours. When the poison does not prove fatal, the recovery occupies several days, and the circulation is slowly restored to its usual state. The post-mortem appearances in cases of poisoning by foxglove are turgescence of the vessels of the brain, and redness of the inner mem- brane of the stomach. In consequence of the frequent use of digitalis in the form of infu- sion or tincture in the practice of medicine, and in consequence, also, of its tendency to accumulate in the system, cases are of frequent occur- rence in which serious symptoms show themselves, without terminating fatally. These symptoms are dryness in the throat, and thirst ; nausea ; headache ; salivation ; giddiness, and dimness of sight, an appearance of sparks before the eyes, and a feeling of pressure on the eyeballs ; with weakness of the limbs, and a weak and rapid pulse. The symptoms arising from the gradual accumulation of the poison in the system are nausea, dryness of the mouth, loss of appetite, and vomiting, and intense thirst ; giddiness, and throbbing of the temples ; restlessness and sleeplessness ; a hot and moist skin ; great languor and depression, with, in most cases, a slow pulse. Sometimes there is diaiThoea, sometimes salivation ; and an increased flow of urine, delirium, spectral illusions, convulsions, and coma, are among the occa- sional symptoms. Fatal Dose. — This has not been accurately ascertained. No poison in common use is more uncertain in its operation ; and in the treat- ment of inflanimatory diseases, as well as in delirium tremens, it is often administered in doses which would have been very unsafe in a state of health. Dr. Pereira cites several cases of disease, both in children and adults, in which the tincture of digitalis was administered in such doses as twenty drops three times a day to an infant, and from ^^ss. to ^i to an adult; but in the cases referred to by him, the natural operation of the poison on the healthy subject was counteracted by disease accompanied by decided febrile action, or by a state ot intoxication attended by great excitement of the circulation. It is also possible that the tincture may not have been, in all these cases, of the best quality. The treatment of poisoning by digitalis will consist in the use of emetics, followed by aperients, and by the free use of vegetable infu- sions containing tannin, such as infusion of nutgalls, or of oak-bark. Substances containing tannin are given with a view of rendering the alkaloid digitalia inert. Green tea or strong coffee may also be given with advantage. Stimulants, such as ammonia, wine, and brandy, should also be administered, and the recumbent posture should be strictly preserved. Friction to the spine, though less indicated than in poisoning by aconite, or when asphyxia is imminent, might be used with advantage ; and, in desperate cases, artificial respiration, and gal- vanic shocks through the heart. Digitalia {digitaline). — Properties. — When pure, this alkaloid is 520 TOBACCO. a white amorphous substance ; when less pure, of a light yellow or brown colour. It is sparingly soluble in cold or hot water, and has an intensely bitter taste. With acids it does not form crystallizable salts. Tests. — a. Sulphuric acid dissolves it, and gives it a deep brown tint, passing to a rich puce colour when heated. After further exposure, it assumes a crimson hue. b. On the addition of a solution of bichro- mate of potash to the recent solution in sulphuric acid, the liquid becomes first yellow, then green, c. A solution of the permanganate of potash added to the solution in sulphuric acid is bleached, d. Nitric and hydrochloric acids dissolve it without change of colour. These reactions were obtained with a specimen of the alkaloid supplied by Mr. Morson. They differ from those given by Dr. Taylor, on the authority of M. Homolle (' On Poisons,' p. 835). The quantity of the alkaloid in the leaves of the plant is less than one per cent. ; and it is believed that a dose of more than one-sixteenth of a grain would produce symptoms of poisoning in the adult. 3. Tobacco (Nicotiana tabacum). The Nicotiana tabacum, or "Virginian tobacco, is a plant which be- longs, as do so many of our chief poisons — hyoscyamus, belladonna, stramonium, and dulcamara— to the artificial class and order Pentan- dria monogynia, and natural order, Solaneae or Solanacea?. Tobacco contains, as the source of its activity, an alkaloid, which, like that contained in conium, is a liquid; and a concrete volatile oil, known as tobacco-camphor. These active ingredients are obtainable from all parts of the plant, and are contained in the infusion and decoction, and in the smoke, blended with carbonate and acetate of ammonia, and several gases. Experiments on Animals. — The effects produced by tobacco on car- nivorous animals (for the herbivora are less affected, and differently) are : nausea, vomiting, sometimes purging, universal tremors, stagger- ing, convulsions, and stupor. In the experiments of Orfila, 3vss. of rappee introduced into a dog's stomach, the gullet being afterwards tied, killed the animal in nine hours; and 3ii applied to a wound killed another animal in an hour. Infusion of tobacco, as appears from the experiments of Sir Benjamin Brodie, paralyses the heart, acting, as other experiments prove, through the nervous system ; but the empyreumatic oil of tobacco does not cause paralysis of the heart, as Sir Benjamin Brodie proved by placing a single drop of it on the tongue of a cat. It caused convulsions and death in two minutes. On opening the body, the heart was found beating with regularity and force. Symptoms. — The effects of tobacco on the human subject are similar to those which it produces in animals. The first symptoms are SYMPTOMS. 521 acceleration and strengthening of the pulse, with very transient excite- ment, sudden giddiness, fainting, and great sickness, accompanied with a weak, quivering pulse. These effects are, for the most part, transient, but occasionally they are more serious, and may even prove fatal. Dr. Marshall Hall relates the case of a young man who smoked two pipes for his first debauch, and was seized, in consequence, with nausea, vomiting, and syncope, then with stupor and stertorous breathing, general spasms, and insensible pupil. Next day the tendency to faint continued, and in the evening the stupor, stertor, and spasms returned, but from that time he recovered steadily. Other authors have reported cases of death from excessive smoking. Fatal results also sometimes follow the use of tobacco infusion or tobacco smoke introduced into the bowels. Severe effects have also followed from the abuse of snuff, from external application of tobacco, and from sleeping surrounded by bales of the weed. Commencement of Symptoms. — The symptoms may show themselves in a few minutes. Fatal Period. — Eighteen minutes is the shortest fatal period. Fatal Dose. — Half a drachm (Copland). Post-mortem Appearances. — These are not very characteristic. Tur- gescence of the vessels of the brain, and marks of inflammation in the stomach have been found. Treatment. — If the tobacco has been taken in substance, and it has not been discharged by spontaneous vomiting, emetics must be first administered. The after treatment must consist of the free use of sti- mulants. NlCOTlNA {Nicotia). — This alkaloid has acted fatally as a poison in two instances: one in Belgium in 1851, when it was administered by Count Bocarme to his brother-in-law, the other in London in 1858, the act being suicidal. The alkaloid acts with the rapidity, and some- what after tlie manner of prussic acid. Dr. Taylor found that a single drop killed a rabbit in three minutes and a half, with tetanic con- vulsions. The victim of Count Bocarme does not seem to have sur- vived five minutes ; and in the suicidal case death was quite as rapid. The patient was observed to stare wildly, and to die without convul- sions, while heaving a deep sigh. The post-mortem appearances in this case were general relaxation of the muscular system, staring eyes, bloated and livid features, the ves- sels of the scalp and membranes of the brain, and those of the lungs, gorged with black blood, and the cjivities of the heart, with the excep- tion of the left auricle, empty. There was intense congestion of the mucous membrane of the stomach, and of the liver. The blood was black and liquid, and, in some parts, had the consistence of treacle. Dr. Taylor detected nicotina in the stomach, liver, and lungs, by a process similar to that of Stas. (See Taylor, * On Poisons,' p. 750.) Properties. — Nicotina resembles conia in being a liquid and volatile 522 LOBEIJA. alkaloid. When quite pure, it is a colourless oily liquid, but becomes of an amber colour on exposure to the air, and deepens in tint by keeping. A drop placed on a white surface of enamelled glass has a green colour, while conia is pink : and the same difference of colour obtains if the liquids are dropped on filtering paper, when they produce a greasy sLain. It has an acrid taste, but a pleasant athereal odour; while conia has a disagreeable odour, which might be mistaken for that of stale tobacco. Otto thus describes the odour of nicotina, and his description is true of two specimens in my possession ; but Dr. Taylor states that a specimen which he examined evolved the odour here described as belonging to conia. Nicotina is soluble in water, in alcohol, and in aether ; and the aqueous solution has a decided alkaline reaction. With acids, the alkaloid forms fixed salts, and with several reagents characteristic crystallizable compounds. Tests. — a. Nicotina resembles conia and the fixed alkaloids in the effect of heat, and in the precipitates which it yields with the solution of iodine in iodine of potassium, and with tannic acid. h. Sulphuric acid combines with it without change of colour, and the mixtuie gives a yellow tinge to a solution of the bichromate of potash, and a pale gi'een to that of the ferridcyanide of potassium, c. Nitric acid also does not change the colour of the alkaloid, d. Terchloride of gold yields an abundant amorphous yellow precipitate, e. Bichloride of platinum yields a yellow crystalline precipitate. /. Bichromate of potash gives a yellow crystalline precipitate, g. Ferridcyanide of po- tassium yields a yellow crystalline precipitate. A. Corrosive sublimate throws down a white deposit, which is found to consist of well-defined groups of transparent plates attached to a darker centre in the form of flowers, winged insects, and bows of ribbon, i. Oxalic acid gives with the alkaloid crystals of oxalate of nicotina. In some of these reactions nicotina resembles ammonia. It is suffi- ciently distinguished from it by the fact, that ammonia reddens tannic acid, and gives with the solution of iodine in iodide of potassium a dark- green precipitate. 4. Lobelia {Lobelia Infiata. Indian Tobacco. Bladder-podded Lobelia). Lobelia infiata belongs to the artificial class and order, Pentandria Monogynia, and natural order Loheliacem. It is a native of North America, and has long been used by the aborigines: it at length became a quack medicine among the American irregular practitioners, was the subject of favourable notice by a clergyman (I))-. Cutler) and of a work by an English physician. Dr. Reece, in the year 1829, in which work it was highly commended as an anti-asthmatic. The herb is usually imported into England by the Shaking Quakers of New Lebanon, North America, compressed into oblong cakes weigh- ing half a pound or a pound each, wrapped in blue paper (Pereira), TREATMENT. 523 Fig. 73. The seeds, and the powder of the seeds, are sold by all the herbalists. Both have proved fatal in several instances in America and in England. The dried herb is of a pale green colour ; it has a nauseous odour, and a burning and acrid taste, closely resembling the taste of tobacco. The taste and odour are believed to be due to a volatile oil, to a resinous alkaloid (lobelin), and to a peculiar acid. The seeds of lobelia are brown grains of the small size shown in fig. 73, and weigh 3176 to a grain. They have the shape and microscopic characters depicted in fig. 73. Lobelia is an active medicine, and a potent poison. In ten grain or scruple doses of the powdered leaves or seeds it is a strong nauseating emetic ; and has, indeed, been termed the emetic weed. A tea-spoonful or a drachm is sufficient to destroy life. The symptoms occasioned by the lobelia are speedy vomiting fol- lowed by distressing nausea, with headache, giddiness, and tremors, copious sweats, and extreme depression. Diarrhoea is sometimes present, and some degree of dysuria is occasionally experienced. Some- times the pulse intermits, as a consequence of its depressant effect on the circulation. The fatal event is ushered in by convulsions. Em- ployed as an enema it acts as tobacco does, causing the same sick- ness and tendency to faint. Fatal Dose. — A case of poisoning by gi of the powdered leaves occurred in England in 1847. Fatal Period. — In this case death happened in about thirty-six hours. Post-mortem Appearances. — The mucous membrane of the stomach is found intensely inflamed, and the vessels of the brain strongly con- gested. The treatment of poisoning by lobelia will consist in promoting vomiting by draughts of warm water, and tickling the throat, follow- ing this up by the free use of stimulants to counteract the depressing effect of the poison. As its effects so closely resemble those of tobacco, it will require the same treatment. ^. CONIUM ( Conium maculatum — HemlocTi. Common or spotted Hemlock). This plant grows abundantly in our hedge-rows all over England, It belongs to the natural order Umbelliferae or parsley tribe, to which tribe also belong the iEthusa cynapium, or fool's parsley, the Cicuta virosa, or water hemlock, the (Enanthe crocata, or water dropwort, and the CEnanthe phellandrium, or fine-leaved water dropwort — all poisonous plants. The plant is readily recognized by its tall, smooth, glossy green 524 LOBELIA. stems, dotted with brownish-purple spots. Its root is tapering, like that of the parsnep, and its leaves have been often mist